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Dr. med. Javier Ruperti

Department of Clinical Research
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Ruperti-Repilado, Francisco Javier, Ladrón, Raquel, Lopez-Ayala, Pedro, Gabra, Beshoy, González-Fernández, Victor, Engele, Leo J, Manso, Begoña, Bouma, Berto J, Gabriel, Harald, Schwitz, Fabienne, Possner, Mathias, Schwerzmann, Markus, Rueda, Joaquín, Buendía-Fuentes, Francisco, Bouchardy, Judith, Ladouceur, Magalie, Dos-Subirà, Laura, Greutmann, Matthias, Tobler, Daniel, & Gallego, Pastora. (2025). Aortic coarctation and long-term morbidity after arterial switch operation: a multicentre international cohort study. Heart, heartjnl–hear2024. https://doi.org/10.1136/heartjnl-2024-325634

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Ruperti-Repilado, Francisco Javier, Wals-Rodriguez, Amadeo, Japon, Miguel Angel, Gonzalez-Calle, Antonio, & Gallego, Pastora. (2025). A calcified, eroded, and thrombosed Mustard: recurrent embolic strokes in a patient with dextro-transpostion of the great arteries corrected by atrial switch - case report. European Heart Journal - Case Reports, 9(4). https://doi.org/10.1093/ehjcr/ytaf150

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Ruperti-Repilado FJ, Coserria-Sánchez F, Wals-Rodríguez A, Guisado A, Díaz-Fernández J, & Gallego P. (2025). Venous congestion in a d-TGA patient after Mustard procedure. REC Interv Cardiol. https://doi.org/doi:10.24875/RECICE.M24000360

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Tran, Fabian, Ruperti-Repilado, Francisco Javier, Haaf, Philip, Lopez-Ayala, Pedro, Greutmann, Matthias, Schwerzmann, Markus, Bouchardy, Judith, Gabriel, Harald, Stambach, Dominik, Schwitter, Juerg, Wustmann, Kerstin, Freese, Michael, Mueller, Christian, & Tobler, Daniel. (2025). NT-proBNP en el ventrículo derecho sistémico, ¿un nuevo valor de corte para la estratificación del riesgo? Revista Espanola De Cardiologia, 78(2), 107–116. https://doi.org/10.1016/j.recesp.2024.05.013

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Tran, Fabian, Ruperti-Repilado, Francisco Javier, Haaf, Philip, Lopez-Ayala, Pedro, Greutmann, Matthias, Schwerzmann, Markus, Bouchardy, Judith, Gabriel, Harald, Stambach, Dominik, Schwitter, Juerg, Wustmann, Kerstin, Freese, Michael, Mueller, Christian, & Tobler, Daniel. (2025). NT-proBNP in systemic right ventricles: a new cutoff level for risk stratification? [Journal-article]. Revista Española de Cardiología (English Edition), 78(2), 107–116. https://doi.org/10.1016/j.rec.2024.05.006

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Ruperti-Repilado, Francisco Javier, Gómez Ciriz, Gorka, & Manso-García, Begoña. (2025). Interrupted Inferior Vena Cava, Partial Anomalous Pulmonary Venous Return and Extra-Mediastinal Superior Vena Cava: A Rare Case of Multilevel Congenital Anomalous Venous Return. Circulation: Cardiovascular Imaging. https://doi.org/10.1161/CIRCIMAGING.124.017917

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Engele, Leo J., González-Fernández, Víctor, Mulder, Barbara J.M., Ruperti-Repilado, Francisco Javier, Abia, Raquel Ladrón, van der Vlist, Kim, Buendía, Francisco, Rueda, Joaquin, Gabriel, Harald, Schrutka, Lore, Bouchardy, Judith, Schwerzmann, Markus, Possner, Mathias, Greutmann, Matthias, Gallego, Pastora, Ladouceur, Magalie, Jongbloed, Monique R.M., Tobler, Daniel, Dos, Laura, & Bouma, Berto J. (2024). Decreased clinical performance in TGA-ASO patients after RVOT interventions; a multicenter European collaboration. International Journal of Cardiology, 407. https://doi.org/10.1016/j.ijcard.2024.132027

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Ruperti-Repilado, Francisco Javier, Tran, Fabian, Haaf, Philip, Lopez-Ayala, Pedro, Greutmann, Matthias, Schwerzmann, Markus, Bouchardy, Judith, Gabriel, Harald, Stambach, Dominik, Rutz, Tobias, Schwitter, Juerg, Wustmann, Kerstin, Freese, Michael, Mueller, Christian, & Tobler, Daniel. (2024). Prognostic Value and Determinants of High-Sensitivity Cardiac Troponin T in Patients With a Systemic Right Ventricle: Insights From the SERVE Trial. Journal of the American Heart Association, 13(10). https://doi.org/10.1161/JAHA.123.034776

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Ruperti-Repilado, Francisco Javier, Haag, Nora, Fischer, Thomas, Santos Lopes, Bruno, Meier, Lukas, Wustmann, Kerstin, Bonassin, Francesca, Attenhofer Jost, Christine, Schwitz, Fabienne, Schwerzmann, Markus, Tobler, Daniel, von Felten, Stefanie, & Greutmann, Matthias. (2024). Impact of pulmonary valve replacement on ventricular function and cardiac events in patients with tetralogy of Fallot. A retrospective cohort study. Revista Espanola de Cardiologia, 77, 408–417. https://doi.org/10.1016/j.recesp.2023.11.010

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Ruperti-Repilado, Francisco Javier, Haag, Nora, Fischer, Thomas, Santos Lopes, Bruno, Meier, Lukas, Wustmann, Kerstin, Bonassin, Francesca, Attenhofer Jost, Christine, Schwitz, Fabienne, Schwerzmann, Markus, Tobler, Daniel, von Felten, Stefanie, & Greutmann, Matthias. (2024). Impact of pulmonary valve replacement on ventricular function and cardiac events in patients with tetralogy of Fallot. A retrospective cohort study [Journal-article]. Revista Española de Cardiología (English Edition), 77(5), 408–417. https://doi.org/10.1016/j.rec.2023.11.007

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Daelman, B., Van Bulck, L., Luyckx, K., Kovacs, A., Van De Bruaene, A., Ladouceur, M., Yang, H.-L., Moon, J. R., Schmidt, A., Lykkeberg, B., Callus, E., De Hosson, M., Sandberg, C., Johansson, B., Hlebowicz, J., Areias, M. E., Amedro, P., Coats, L., Mandalenakis, Z., et al. (2024). Frailty and Cognitive Function in Middle-Aged and Older Adults With Congenital Heart Disease. Journal of the American College of Cardiology, 83(12), 1149–1159. https://doi.org/10.1016/j.jacc.2024.01.021

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Ladouceur, M., Ruperti-Repilado, F. J., & Rutz, T. (2024). Arterial switch operation: A surgical triumph with long-term management challenges. International Journal of Cardiology Congenital Heart Disease, 15. https://doi.org/10.1016/j.ijcchd.2023.100487

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Fusco, Flavia, Krasuski, Richard A., Sadeghi, Soraya, Rosenbaum, Marlon S., Lewis, Matthew J., Carazo, Matthew R., Rodriguez, Fred H., Halpern, Dan G., Feinberg, Jodi L., Galilea, Francisca A., Baraona, Fernando, Cedars, Ari M., Ko, Jong M., Porayette, Prashob, Maldonado, Jennifer R., Frogoudaki, Alexandra A., Nir, Amiram, Chaudhry, Anisa, John, Anitha S., et al. (2023). COVID-19–Related Thrombotic and Bleeding Events in Adults With Congenital Heart Disease. JACC: Advances, 2(10). https://doi.org/10.1016/j.jacadv.2023.100701

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Greutmann, Matthias, Tobler, Daniel, Engel, Reto, Heg, Dik, Mueller, Christian, Frenk, André, Gabriel, Harald, Rutz, Tobias, Buechel, Ronny R., Willhelm, Matthias, Trachsel, Lukas, Freese, Michael, Ruperti-Repilado, Francisco Javier, Valsangiacomo Buechel, Emanuela, Beitzke, Dietrich, Haaf, Philip, Wustmann, Kerstin, Schwitz, Fabienne, Possner, Mathias, et al. (2023). Effect of phosphodiesterase-5 inhibition on SystEmic Right VEntricular size and function. A multicentre, double-blind, randomized, placebo-controlled trial: SERVE. European Journal of Heart Failure, 25(7), 1105–1114. https://doi.org/10.1002/ejhf.2924

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Ruperti-Repilado FJ, Baumgartner H, Bouma B, Bouchardy J, Budts W, Campens L, Chessa M, Jesús Del Cerro Marin M, Gabriel H, Gallego P, González EA, Jensen AS, Ladouceur M, Lockhart C, Miranda-Barrio B, Morissens M, Escobar EM, Pasquet A, Soriano JR, et al. (2023). The coronavirus disease pandemic among adult congenital heart disease patients and the lessons learnt – results of a prospective multicenter european registry. International Journal of Cardiology Congenital Heart Disease, 11, 100428. https://doi.org/10.1016/j.ijcchd.2022.100428

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Ruperti-Repilado, Francisco Javier, Van Der Stouwe, Jan Gerrit, Haaf, Philip, Mueller, Christian, Läubli, Heinz, Pfister, Otmar, Rothschild, Sacha I, & Kuster, Gabriela M. (2022). Case report of elevation of high-sensitivity cardiac troponin T in the absence of cardiac involvement in immune checkpoint inhibitor-associated myositis. European Heart Journal - Case Reports, 6(9), ytac353. https://doi.org/10.1093/ehjcr/ytac353

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Lu, C.-W., Wang, J.-K., Yang, H.-L., Kovacs, A. H., Luyckx, K., Ruperti-Repilado, F. J., Van De Bruaene, A., Enomoto, J., Sluman, M. A., Jackson, J. L., Khairy, P., Cook, S. C., Chidambarathanu, S., Alday, L., Oechslin, E., Eriksen, K., Dellborg, M., Berghammer, M., Johansson, B., et al. (2022). Heart Failure and Patient-Reported Outcomes in Adults With Congenital Heart Disease from 15 Countries. Journal of the American Heart Association, 11(9). https://doi.org/10.1161/JAHA.121.024993

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Greutmann M, Ruperti J, Schwitz F, Haag N, Santos Lopes B, Meier L, Babic D, Valsangiacomo Buechel E, Kellenberger C, Bonassin F, Attenhofer Jost C, Schwerzmann M, Wustmann K, & Tobler D. (2022). High Variability of Right Ventricular Volumes and Function in Adults with Severe Pulmonary Regurgitation Late After Tetralogy of Fallot Repair. American Journal of Cardiology, 166, 88–96. https://doi.org/10.1016/j.amjcard.2021.11.022

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Ruperti-Repilado FJ, Affolter J, Bouchardy J, Gabriel H, Stämpfli SF, Engel R, Schwerzmann M, Greutmann M, & Tobler D. (2022). Young adults after arterial switch operation for transposition of the great arteries in Switzerland: a growing population. Swiss Medical Weekly, 152, w30114. https://doi.org/10.4414/smw.2022.w30114

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Schwerzmann, M., & Ruperti-Repilado, F. J. (2022). Adult congenital heart disease and the coronavirus disease 2019: How to deal with uncertainty. Kardiologia Polska, 80(2), 123–125. https://doi.org/10.33963/KP.a2022.0023

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Schwerzmann M, Ruperti-Repilado FJ, Baumgartner H, Bouma B, Bouchardy J, Budts W, Campens L, Chessa M, Del Cerro Marin MJ, Gabriel H, Gallego P, Garcia-Orta R, Gonzalez AE, Jensen AS, Ladouceur M, Miranda-Barrio B, Morissens M, Pasquet A, Rueda J, et al. (2021). Clinical outcome of COVID-19 in patients with adult congenital heart disease. Heart, 107(15), 1226–1232. https://doi.org/10.1136/heartjnl-2020-318467

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Ruperti-Repilado FJ, Tobler D, Greutmann M, Bouchardy J, Ladouceur M, Dos-Subira L, Gallego P, Gabriel H, Bouma B, Schwerzmann M, & EPOCH. (2021). Risk stratification of adults with congenital heart disease during the COVID-19 pandemic: Insights from a multinational survey among European experts. Open Heart, 8(1). https://doi.org/10.1136/openhrt-2020-001455

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Broberg CS, Kovacs AH, Sadeghi S, Rosenbaum MS, Lewis MJ, Carazo MR, Rodriguez FH 3rd, Halpern DG, Feinberg J, Galilea FA, Baraona F, Cedars AM, Ko JM, Porayette P, Maldonado J, Sarubbi B, Fusco F, Frogoudaki AA, Nir A, et al. (2021). COVID-19 in Adults With Congenital Heart Disease. Journal of the American College of Cardiology, 77(13), 1644–1655. https://doi.org/10.1016/j.jacc.2021.02.023

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Ruperti-Repilado, F. J., Thomet, C., & Schwerzmann, M. (2021). 2020 ESC guidelines on treatment of adult congenital heart disease (ACHD) ESC-Leitlinie 2020 zur Behandlung von Erwachsenen mit angeborenem Herzfehler (ACHD). Herz, 46(1), 14–27. https://doi.org/10.1007/s00059-020-05003-0

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Gallego, P., Ruperti-Repilado, F. J., & Schwerzmann, M. (2020). Adults with congenital heart disease during the coronavirus disease 2019 (COVID-19) pandemic: are they at risk? Adultos con cardiopatía congénita durante la pandemia de COVID-19: ¿población de riesgo? Revista Espanola de Cardiologia, 73(10), 795–798. https://doi.org/10.1016/j.recesp.2020.06.026

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Gallego, P., Ruperti-Repilado, F. J., & Schwerzmann, M. (2020). Adults with congenital heart disease during the coronavirus disease 2019 (COVID-19) pandemic: are they at risk? [Journal-article]. Revista Española de Cardiología (English Edition), 73(10), 795–798. https://doi.org/10.1016/j.rec.2020.06.016

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Ruperti-Repilado FJ, Ladouceur M, Gallego P, Dos L, Rueda Soriano J, Bouma B, Gabriel H, Schwerzmann M, Bouchardy J, Tobler D, & Greutmann M. (2020). Comprehensive Long-Term Follow up of Adults with Arterial Switch Operation– European Collaboration for Prospective Outcome Research in Congenital Heart Disease (EPOCH-ASO)–Study Design and Protocols. Congenital Heart Disease, 15(5), 338. https://doi.org/ https://doi.org/10.32604/CHD.2020.012599

Ruperti-Repilado, Francisco Javier, Haefliger, Simon, Rehm, Sophia, Zweier, Markus, Rentsch, Katharina M., Rentsch, Katharina M., Blum, Johannes, Jetter, Alexander, Heim, Markus, Leuppi-Taegtmeyer, Anne, Terracciano, Luigi, & Bernsmeier, Christine. (2019). Danger of Herbal Tea: A Case of Acute Cholestatic Hepatitis Due to; Artemisia annua; Tea. Frontiers in medicine, 6, 221. https://doi.org/10.3389/fmed.2019.00221

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Ruperti Repilado FJ, Doerig L, Blum S, Aeschbacher S, Krisai P, Ammann P, Erne P, Moschovitis G, di Valentino M, Shah D, Schläpfer J, Stempfel S, Kühne M, Sticherling C, Osswald S, & Conen D. (2018). Prevalence and predictors of atrial fibrillation type among individuals with recent onset of atrial fibrillation. Swiss Medical Weekly, 148(37-38), w14652. https://doi.org/10.4414/smw.2018.14652

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Krisai P, Aeschbacher S, Ruperti Repilado FJ, Schoen T, Reusser A, Meier M, Todd J, Estis J, Risch M, Risch L, & Conen D. (2017). Healthy lifestyle and glucagon-like peptide-1 in young and healthy adults: A population-based study. Preventive Medicine, 101, 72–76. https://doi.org/10.1016/j.ypmed.2017.05.025

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Ruperti Repilado FJ, Aeschbacher S, Bossard M, Schoen T, Gugganig R, van der Stouwe JG, Krisai P, Kofler T, Buser A, Risch M, Risch L, Mueller C, & Conen D. (2016). Relationship of N-Terminal fragment of Pro-B-Type Natriuretic Peptide and copeptin with erythrocytes-related parameters: A population-based study. Clinical Biochemistry, 49(9), 651–656. https://doi.org/10.1016/j.clinbiochem.2016.01.021

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Aeschbacher, Stefanie, Bossard, Matthias, Ruperti Repilado, Francisco Javier, Good, Nathalie, Schoen, Tobias, Zimny, Matylda, Probst-Hensch, Nicole M., Schmidt-Trucksäss, Arno, Risch, Martin, Risch, Lorenz, & Conen, David. (2016). Healthy lifestyle and heart rate variability in young adults. European Journal of Preventive Cardiology, 23(10), 44–1037. https://doi.org/10.1177/2047487315623708

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