Research Focus

Neurology

Area of Research

Acute ischemic stroke, in particular the interventional treatment of medium vessel occlusions and workflow approaches to optimize patient outcomes.

Hemorrhagic stroke, new interventional approaches for the treatment of intracranial aneurysms and arteriovenous malformations.

Approved Research Projects

DISTAL Study: EnDovascular therapy plus best medical treatment (BMT) versus BMT alone for MedIum VeSsel Occlusion sTroke - a prAgmatic, international, multicentre, randomized trial: Randomized, SNF funded study to investigate the efficacy of endovascular therapy in medium vessel occlusion stroke patients

ICARUS Study: IntraCranial Atherosclerosis Related large-vessel occlusion treated with Urgent Stenting - a pragmatic, international, multicentre, randomized trial, SNF funded study to investigate the efficacy of intracranial stenting in large vessel occlusion stroke patients with failure of reperfusion after conventional therapy due to intracranial artherosclerosis

SPINNERS Study: ProSPective evaluation of the dIagnostic accuracy of siNe spiN non-contrast flat-dEtectoR CT (FDCT) for the detection of intracranial hemorrhage in Stroke patients - an open labelled, multicenter, non-inferiority comparison to multi detector CT (MDCT) with blinded assessment of outcome events

HemEXPLO Study: Detection of an endovascular treatment target in patients with an acute, spontaneous intracerebral Hemorrhage – an EXPLOrative pilot study

Collaborations

National Collaborations

• Prof. Dr. Urs Fischer, Inselspital Bern
• Prof. Dr. Jan Gralla, Inselspital Bern
• PD Dr. Mira Katan, University Hospital Zürich
• Prof. Dr. Paolo Machi, Hôpitaux universitaires de Genève

International Collaborations

• Prof. Dr. David S Liebeskind, University of California LA, USA
• Prof. Dr. Mayank Goyal, University of Calgary, Canada
• Prof. Dr. Alejandro M. Spiotta, Medical University of South Carolina, USA
• Prof. Dr. Jens Fiehler, University Clinic Hamburg Eppendorf, Germany
• Dr. Adam S Arthur, M.D., M.P.H., Semmes Murphy Clinic, Memphis, USA
• Prof. Dr. Martin Dichgans, Ludwig Maximillian University Munich, Germany

Ongoing Research Projects

ASSIST Register: Observational register study evaluating interventional treatment approaches in large vessel occlusion stroke

SURF Study: Observational register study evaluating the SMART coil family for the treatment of intracranial aneurysms

Save ChildS: Observational study evaluating the efficacy and safety of endovascular treatment for large vessel occlusion stroke in children

TENSION Study: Efficacy and safety of ThrombEctomy iN Stroke with extended leSION and extended time window: a randomized controlled trial

SELECT 2 Study: A Randomized Controlled Trial to Optimize Patient’s Selection for Endovascular Treatment in Acute Ischemic Stroke

COATING Study: Prospective, multi-center randomized controlled trial to assess safety and efficacy p64 MW HPC Flow Modulation Device under single antiplatelet therapy compared to p64 MW Flow Modulation Device under dual antiplatelet therapy

ACT in Stroke Study: Anaesthesiological Care for Thrombectomy in Stroke (ACT in Stroke): A Randomized Controlled Multicentre Study