Research Focus

Neurology

Area of Research

Development of quantitative MR and electrophysiological markers for the characterization of neurodegenerative diseases (motor neuron diseases, progressive MS)

Approved Research Projects

2017 - Spinal Cord Imaging in Post Polio Syndrome. Sub-study to the Citrulline Study (EKNZ 2015-221).

2018 - Spinal cord gray matter imaging in Amyotrophic Lateral Sclerosis (EKNZ:2018-0032).

2019 - Spinal cord gray matter imaging - a novel biomarker for Spinal Muscular Atrophy (EKNZ 2019-01228).

2020 - Quantitative Spinal Cord Gray and White Matter Imaging in Amyotrophic Lateral Sclerosis – a post mortem validation study (2020-02179)

2022 - Quantitative Spinal Cord Gray Matter lmaging - a Novel Biomarker for Post-Polio Syndrome, a 5 year follow-up study (2022-01502)

2024 - 2028 Advancing Neuromuscular Disease Evaluation: Developing Novel Multiparametric MRI Methods for Myotonic Dystrophy Assessment and Management (collaboration with PD Dr. Francesco Santini) (SNF, Projektnummer 219674)

Collaborations

National Collaborations

Prof. Oliver Bieri, Department of Biomedical Engineering, University of Basel
Prof. Philippe Cattin, Department of Biomedical Engineering, University of Basel
Prof. Marco Düring, MIAC AG, Basel
Prof. Dirk Fischer, UKBB, Basel
Prof. Cristina Granziera, ThINK, Department of Biomedical Engineering
Prof. Jens Kuhle, Department of Biomedicine, University of Basel
Prof. Eva Scheuer, PD Dr. Claudia Lenz, Institut für Rechtsmedizin, Basel
PD Dr. Mark Sollberger, Memory Clinic, Basel
Prof. Markus Weber, Kantonsspital St.Gallen, Muskelzentrum/ALS Clinic
PD Dr. Francesco Santini, Radiologische Physik, Universitaetsspital Basel
PD Dr. Netzer, Spinale Chirurgie, Universitaetsspital Basel

International Collaborations

Prof. Roland Henry, UCSF, San Francisco, USA
PD Thorsten Langer, Universitätskinderklinik, Freiburg i. B.

Ongoing Research Projects

Spinal cord gray matter imaging in ALS (EKNZ:2018-0032). Active recruiting.
Quantitative Spinal Cord Gray and White Matter Imaging in Amyotrophic Lateral Sclerosis – a post mortem validation study (2020-02179). Active recruiting.
Quantitative Spinal Cord Gray Matter lmaging - a Novel Biomarker for Post-Polio Syndrome, a 6 year follow-up study (2022-01502). Active recruiting.
Spinal cord gray matter imaging - a novel biomarker for Spinal Muscular Atrophy. (EKNZ 2019-01228). Completed.
Brainstem Atrophy in Multiple Sclerosis and Neurodegenerative diseases. Substudy to the Gene-MSA Study (EKNZ 285/11).
Advancing Neuromuscular Disease Evaluation: Developing Novel Multiparametric MRI Methods for Myotonic Dystrophy Assessment and Management (not yet recruiting)

[FG] Schlaeger Regina

Head of Research Unit

Prof. Dr. med. Regina Maria Marga Schläger

Projects & Collaborations

Advancing Neuromuscular Disease Evaluation: Developing Novel Multiparametric MRI Methods for Myotonic Dystrophy Assessment and Management

Research Project | 2 Project Members

No Description available

Characterization and early prognostic markers of autonomic dysfunction in patients with transthyretin amyloidosis and asymptomatic carriers

Research Project | 1 Project Members

No Description available