Research Group Regina Schläger
Research Focus
Neurology
Area of Research
Development of quantitative MR and electrophysiological markers for the characterization of neurodegenerative diseases (motor neuron diseases, progressive MS)
Approved Research Projects
2017 - Spinal Cord Imaging in Post Polio Syndrome. Sub-study to the Citrulline Study (EKNZ 2015-221).
2018 - Spinal cord gray matter imaging in Amyotrophic Lateral Sclerosis (EKNZ:2018-0032).
2019 - Spinal cord gray matter imaging - a novel biomarker for Spinal Muscular Atrophy (EKNZ 2019-01228).
2020 - Quantitative Spinal Cord Gray and White Matter Imaging in Amyotrophic Lateral Sclerosis – a post mortem validation study (2020-02179)
2022 - Quantitative Spinal Cord Gray Matter lmaging - a Novel Biomarker for Post-Polio Syndrome, a 5 year follow-up study (2022-01502)
2024 - 2028 Advancing Neuromuscular Disease Evaluation: Developing Novel Multiparametric MRI Methods for Myotonic Dystrophy Assessment and Management (collaboration with PD Dr. Francesco Santini) (SNF, Projektnummer 219674)
Collaborations
National Collaborations
- Prof. Oliver Bieri, Department of Biomedical Engineering, University of Basel
- Prof. Philippe Cattin, Department of Biomedical Engineering, University of Basel
- Prof. Marco Düring, MIAC AG, Basel
- Prof. Dirk Fischer, UKBB, Basel
- Prof. Cristina Granziera, ThINK, Department of Biomedical Engineering
- Prof. Jens Kuhle, Department of Biomedicine, University of Basel
- Prof. Eva Scheuer, PD Dr. Claudia Lenz, Institut für Rechtsmedizin, Basel
- PD Dr. Mark Sollberger, Memory Clinic, Basel
- Prof. Markus Weber, Kantonsspital St.Gallen, Muskelzentrum/ALS Clinic
- PD Dr. Francesco Santini, Radiologische Physik, Universitaetsspital Basel
- PD Dr. Netzer, Spinale Chirurgie, Universitaetsspital Basel
International Collaborations
- Prof. Roland Henry, UCSF, San Francisco, USA
- PD Thorsten Langer, Universitätskinderklinik, Freiburg i. B.
Ongoing Research Projects
- Spinal cord gray matter imaging in ALS (EKNZ:2018-0032). Active recruiting.
- Quantitative Spinal Cord Gray and White Matter Imaging in Amyotrophic Lateral Sclerosis – a post mortem validation study (2020-02179). Active recruiting.
- Quantitative Spinal Cord Gray Matter lmaging - a Novel Biomarker for Post-Polio Syndrome, a 6 year follow-up study (2022-01502). Active recruiting.
- Spinal cord gray matter imaging - a novel biomarker for Spinal Muscular Atrophy. (EKNZ 2019-01228). Completed.
- Brainstem Atrophy in Multiple Sclerosis and Neurodegenerative diseases. Substudy to the Gene-MSA Study (EKNZ 285/11).
- Advancing Neuromuscular Disease Evaluation: Developing Novel Multiparametric MRI Methods for Myotonic Dystrophy Assessment and Management (not yet recruiting)