[FG] Schlaeger Regina

Research Focus

Neurology

Area of Research

Development of quantitative MR and electrophysiological markers for the characterization of neurodegenerative diseases (motor neuron diseases, progressive MS)

Approved Research Projects

2017 - Spinal Cord Imaging in Post Polio Syndrome. Sub-study to the Citrulline Study (EKNZ 2015-221).

2018 - Spinal cord gray matter imaging in Amyotrophic Lateral Sclerosis (EKNZ:2018-0032).

2019 - Spinal cord gray matter imaging - a novel biomarker for Spinal Muscular Atrophy (EKNZ 2019-01228).

2020 - Quantitative Spinal Cord Gray and White Matter Imaging in Amyotrophic Lateral Sclerosis – a post mortem validation study (2020-02179)

2022 - Quantitative Spinal Cord Gray Matter lmaging - a Novel Biomarker for Post-Polio Syndrome, a 5 year follow-up study (2022-01502)

2024 - 2028 Advancing Neuromuscular Disease Evaluation: Developing Novel Multiparametric MRI Methods for Myotonic Dystrophy Assessment and Management (collaboration with PD Dr. Francesco Santini) (SNF, Projektnummer 219674)

Collaborations

National Collaborations

• Prof. Oliver Bieri, Department of Biomedical Engineering, University of Basel
• Prof. Philippe Cattin, Department of Biomedical Engineering, University of Basel
• Prof. Marco Düring, MIAC AG, Basel
• Prof. Dirk Fischer, UKBB, Basel
• Prof. Cristina Granziera, ThINK, Department of Biomedical Engineering
• Prof. Jens Kuhle, Department of Biomedicine, University of Basel
• Prof. Eva Scheuer, PD Dr. Claudia Lenz, Institut für Rechtsmedizin, Basel
• PD Dr. Mark Sollberger, Memory Clinic, Basel
• Prof. Markus Weber, Kantonsspital St.Gallen, Muskelzentrum/ALS Clinic
• PD Dr. Francesco Santini, Radiologische Physik, Universitaetsspital Basel 
• PD Dr. Netzer, Spinale Chirurgie, Universitaetsspital Basel 

International Collaborations

• Prof. Roland Henry, UCSF, San Francisco, USA
• PD Thorsten Langer, Universitätskinderklinik, Freiburg i. B.

Ongoing Research Projects

• Spinal cord gray matter imaging in ALS (EKNZ:2018-0032). Active recruiting.
• Quantitative Spinal Cord Gray and White Matter Imaging in Amyotrophic Lateral Sclerosis – a post mortem validation study (2020-02179). Active recruiting. 
• Quantitative Spinal Cord Gray Matter lmaging - a Novel Biomarker for Post-Polio Syndrome, a 6 year follow-up study (2022-01502). Active recruiting.
• Spinal cord gray matter imaging - a novel biomarker for Spinal Muscular Atrophy. (EKNZ 2019-01228). Completed.
• Brainstem Atrophy in Multiple Sclerosis and Neurodegenerative diseases. Substudy to the Gene-MSA Study (EKNZ 285/11).
• Advancing Neuromuscular Disease Evaluation: Developing Novel Multiparametric MRI Methods for Myotonic Dystrophy Assessment and Management (not yet recruiting)