Dr. Jennifer Brown

Brown, Jennifer Anne, Ringera, Isaac Kaumbuthu, Luoga, Ezekiel, Bresser, Moniek, Mothobi, Buoang, Kabundi, Lorraine, Ilunga, Mulume, Mokhele, Kuena, Isaac, Andreas Boy, Tsoaeli, Ntsepiseng, Mbaya, Thomas, Simba, Brenda, Mayogu, Kasasi, Mabula, Elizabeth, Cheleboi, Molisana, Molatelle, Mamello, Kimera, Namvua, Mollel, Getrud Joseph, Sando, David, et al. (2024). Resistance-informed versus empirical management of viraemia in children and adolescents with HIV in Lesotho and Tanzania (GIVE MOVE trial): a multisite, open-label randomised controlled trial [Journal-article]. The Lancet Global Health, 12(8), e1312–e1322. https://doi.org/10.1016/s2214-109x(24)00183-9

Tschumi, Nadine, Lukau, Blaise, Tlali, Katleho, Motaboli, Lipontso, Kao, Mpho, Kopo, Mathebe, Hänggi, Kathrin, Mokebe, Moleboheng, Naegele, Klaudia, Ayakaka, Irene, Leuzinger, Karoline, Brown, Jennifer A, & Labhardt, Niklaus D. (2024). Emergence of acquired dolutegravir resistance in treatment-experienced people with HIV in Lesotho [Journal-article]. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciae185

Devendra, Akash, Kohler, Maurus, Letsika, Motlatsi, Khooa, Hape, Motaboli, Lipontso, Lerotholi, Malebanye, Tschumi, Nadine, Labhardt, Niklaus D., & Brown, Jennifer A. (2024). HIV viral suppression in children and adolescents 2 years after transition to dolutegravir: a multicentre cohort study [Journal-article]. AIDS (London, England), 38, 1013–1023. https://doi.org/10.1097/qad.0000000000003835

Kohler, Maurus, Brown, Jennifer A., Tschumi, Nadine, Lerotholi, Malebanye, Motaboli, Lipontso, Mokete, Moliehi, Chammartin, Frédérique, & Labhardt, Niklaus D. (2024). Clinical Relevance of Human Immunodeficiency Virus Low-level Viremia in the Dolutegravir era: Data From the Viral Load Cohort North-East Lesotho (VICONEL). Open Forum Infectious Diseases, 11. https://doi.org/10.1093/ofid/ofae013

Brown JA, Hauser A, Abela IA, Pasin C, Epp S, Mohloanyane T, Nsakala BL, Trkola A, Labhardt ND, Kouyos RD, & Günthard HF. (2023). Seroprofiling of Antibodies Against Endemic Human Coronaviruses and Severe Acute Respiratory Syndrome Coronavirus 2 in a Human Immunodeficiency Virus Cohort in Lesotho: Correlates of Antibody Response and Seropositivity. The Journal of Infectious Diseases, 228(8), 1042–1054. https://doi.org/10.1093/infdis/jiad197

Labhardt ND, Brown JA, Sass N, Ford N, & Rosen S. (2023). Treatment Outcomes After Offering Same-Day Initiation of Human Immunodeficiency Virus Treatment-How to Interpret Discrepancies Between Different Studies. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 77(8), 1176–1184. https://doi.org/10.1093/cid/ciad317

Tschumi N, Lerotholi M, Motaboli L, Mokete M, Labhardt ND, & Brown JA. (2023). Two-year outcomes of treatment-experienced adults after programmatic transitioning to dolutegravir: longitudinal data from the VICONEL HIV cohort in Lesotho. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. https://doi.org/10.1093/cid/ciad390

Brown, Jennifer A., Nsakala, Bienvenu L., Mokhele, Kuena, Rakuoane, Itumeleng, Muhairwe, Josephine, Urda, Lorena, Amstutz, Alain, Tschumi , Nadine, Klimkait, Thomas, & Labhardt, Niklaus D. (2022). Viral suppression after transition from nonnucleoside reverse transcriptase inhibitor- to dolutegravir-based antiretroviral therapy: a prospective cohort study in Lesotho (DO-REAL study). HIV medicine, 23(3), 287–293. https://doi.org/10.1111/hiv.13189

Jawaid A, Brown JA, & Schulz PE. (2015). Diabetes mellitus in amyotrophic lateral sclerosis: Dr. Jekyll or Mr. Hyde? (Patent No. 11). 22(11), Article 11. https://doi.org/10.1111/ene.12660

Brown, Jennifer A., Motaboli, Lipontso, Lerotholi, Malebanye, Kohler, Maurus, Hänggi, Kathrin, Mokete, Moliehi, Chakely, Makobefo G., Kao, Mpho, Kopo, Mathebe, Mokebe, Moleboheng, Nsakala, Bienvenu L., Lukau, Blaise, Ayakaka, Irene, Amstutz, Alain, Ehmer, Jochen, Klimkait, Thomas, Glass, Tracy R., Muhairwe, Josephine, Chammartin, Frédérique, et al. (2024). Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2022 - cohort description, test volumes, predictors of viraemia, and the road ahead [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.03.12.24304025

Tschumi, Nadine, Lukau, Blaise, Tlali, Katleho, Motaboli, Lipontso, Kao, Mpho, Kopo, Mathebe, Hänggi, Kathrin, Mokebe, Moleboheng, Naegele, Klaudia, Ayakaka, Irene, Leuzinger, Karoline, Brown, Jennifer A., & Labhardt, Niklaus Daniel. (2024). Emergence of Acquired Dolutegravir Resistance in Treatment-Experienced People with HIV in Lesotho [Posted-content]. Elsevier BV. https://doi.org/10.2139/ssrn.4683840

Kopo, M., Lejone, T. I., Tschumi, N., Glass, T. R., Kao, M., Brown, J. A., Seiler, O., Muhairwe, J., Moletsane, N., Labhardt, N. D., & Amstutz, A. (2023). Effectiveness of a peer educator-coordinated preference-based differentiated service delivery model on viral suppression among young people living with HIV in Lesotho: the PEBRA cluster-randomized trial. PLoS Med, 20(1), e1004150. https://doi.org/10.1371/journal.pmed.1004150

Seiler, O., Kopo, M., Kao, M., Lejone, T. I., Tschumi, N., Glass, T. G., Brown, J. A., Labhardt, N. D., & Amstutz, A. (2023). HIV care preferences among young people living with HIV in Lesotho: a secondary data analysis of the PEBRA cluster randomized trial. AIDS Res Treat, 2023, 8124192. https://doi.org/10.1155/2023/8124192

Seiler, O., Kopo, M., Kao, M., Lejone, T. I., Tschumi, N., Glass, T. R., Brown, J. A., Labhardt, N. D., & Amstutz, A. (2022). HIV care preferences among young people living with HIV in Lesotho: A secondary data analysis of the PEBRA cluster randomized trial [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.07.29.22278205

Brown, J. A., Nsakala, B. L., Mokhele, K., Rakuoane, I., Muhairwe, J., Glass, T. R., Amstutz, A., Tschumi, N., Belus, J. M., Klimkait, T., & Labhardt, N. D. (2022). Dolutegravir in real life: self-reported mental and physical health outcomes after transitioning from efavirenz- to dolutegravir-based antiretroviral therapy in a prospective cohort study in Lesotho. HIV Med, 24(2), 153–162. https://doi.org/10.1111/hiv.13352

Kopo, M., Lejone, T. I., Tschumi, N., Glass, T. R., Kao, M., Brown, J. A., Seiler, O., Muhairwe, J., Moletsane, N., Labhardt, N. D., & Amstutz, A. (2022). Effectiveness of a Peer Educator-Coordinated Preference-Based Differentiated Delivery Model on Viral Suppression Among Young People Living with HIV in Lesotho: The PEBRA Cluster Randomized Trial [Journal-article]. In SSRN Electronic Journal. https://doi.org/10.2139/ssrn.4019324

Muhairwe, J. A., Brown, J. A., Motaboli, L., Nsakala, B. L., Lerotholi, M., Amstutz, A., Klimkait, T., Glass, T. R., & Labhardt, N. D. (2022). The suboptimal pediatric HIV viral load cascade: multidistrict cohort study among children taking antiretroviral therapy in Lesotho, Southern Africa. Pediatr Infect Dis J, 41(3), e75–e80. https://doi.org/10.1097/inf.0000000000003415

Tschumi, N., Lerotholi, M., Kopo, M., Kao, M., Lukau, B., Nsakala, B., Chejane, N., Motaboli, L., Lee, T., Barnabas, R., Shapiro, A. E., van Heerden, A., Lejone, T. I., Amstutz, A., Brown, J. A., Heitner, J., Belus, J. M., Chammartin, F., & Labhardt, N. D. (2022). Assessment of a viral load result-triggered automated differentiated service delivery model for people taking ART in Lesotho (the VITAL study): study protocol of a cluster-randomized trial. PLoS One, 17(5), e0268100. https://doi.org/10.1371/journal.pone.0268100

Brown, J. A., Amstutz, A., Nsakala, B. L., Seeburg, U., Vanobberghen, F., Muhairwe, J., Klimkait, T., Daniel Labhardt, N., & Daniel Labhardt, N. (2021). Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in resource-limited settings: a pre-planned analysis from the SESOTHO trial. The Journal of Antimicrobial Chemotherapy, 76(5), 1294–1298. https://doi.org/10.1093/jac/dkab025

Brown, J. A., Mbunkah, H. A., Lejone, T. I., Ringera, I., Cheleboi, M., Klimkait, T., Metzner, K. J., Gunthard, H. F., Labhardt, N. D., Kouyos, R. D., & Tschumi, N. (2021). Emergence of human immunodeficiency virus-1 drug resistance during the 3-month World Health Organization-recommended enhanced adherence counseling period in the CART-1 cohort study. Open Forum Infect Dis, 8(5), ofab046. https://doi.org/10.1093/ofid/ofab046

Brown, Jennifer Anne, Ringera, Isaac, Luoga, Ezekiel, Cheleboi, Molisana, Kimera, Namvua, Muhairwe, Josephine, Kayembe, Buntshi Paulin, Molapo Hlasoa, Mosa, Kabundi, Lorraine, Yav, Ching Wey David, Mothobi, Buoang, Thahane, Lineo, Amstutz, Alain, Bachmann, Nadine, Mollel, Getrud Joseph, Bresser, Moniek, Glass, Tracy Renée, Paris, Daniel Henry, Klimkait, Thomas, et al. (2020). Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania. BMC infectious diseases, 20(1), 773. https://doi.org/10.1186/s12879-020-05491-9

Lejone, Thabo Ishmael, Kopo, Mathebe, Bachmann, Nadine, Brown, Jennifer Anne, Glass, Tracy Renée, Muhairwe, Josephine, Matsela, Tebatso, Scherrer, Ramona, Chere, Lebohang, Namane, Tilo, Labhardt, Niklaus Daniel, & Amstutz, Alain. (2020). PEBRA trial - effect of a peer-educator coordinated preference-based ART service delivery model on viral suppression among adolescents and young adults living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho. BMC Public Health, 20(1), 425. https://doi.org/10.1186/s12889-020-08535-6

Amstutz, Alain, Brown, Jennifer Anne, Ringera, Isaac, Muhairwe, Josephine, Lejone, Thabo Ishmael, Klimkait, Thomas, Glass, Tracy Renée, & Labhardt, Niklaus Daniel. (2019). Engagement in care, viral suppression, drug resistance and reasons for non-engagement after home-based same-day ART initiation in Lesotho: a two-year follow-up of the CASCADE trial. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 71(10), 2608–2614. https://doi.org/10.1093/cid/ciz1126

Courlet, Perrine, Decosterd, Laurent Arthur, Brown, Jennifer Anne, Alves Saldanha, Susana, Marzolini, Catia, Cavassini, Matthias, Stoeckle, Marcel, Csajka, Chantal, Labhardt, Niklaus Daniel, Calmy, Alexandra, & Swiss HIV Cohort Study,. (2019). Emtricitabine and lamivudine concentrations in saliva : a simple suitable test for treatment adherence. Journal of Antimicrobial Chemotherapy, 74(8), 2468–2470. https://doi.org/10.1093/jac/dkz181