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PD Dr. sc. nat. Francis Jacob

Department of Biomedicine
Profiles & Affiliations

Selected Publications

Cumin, Cécile, Gee, Lindsay, Litfin, Thomas, Muchabaiwa, Ropafadzo, Martin, Gael, Cooper, Oren, Heinzelmann-Schwarz, Viola, Lange, Tobias, von Itzstein, Mark, Jacob, Francis, & Everest-Dass, Arun. (2024). Highly Sensitive Spatial Glycomics at Near-Cellular Resolution by On-Slide Derivatization and Mass Spectrometry Imaging. Analytical Chemistry, 96(28), 11163–11171. https://doi.org/10.1021/acs.analchem.3c05984

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Coelho, Ricardo, Tozzi, Alessandra, Disler, Muriel, Lombardo, Flavio, Fedier, André, López, Mónica Núñez, Freuler, Florian, Jacob, Francis, & Heinzelmann-Schwarz, Viola. (2022). Overlapping gene dependencies for PARP inhibitors and carboplatin response identified by functional CRISPR-Cas9 screening in ovarian cancer. Cell Death and Disease, 13(10), 909. https://doi.org/10.1038/s41419-022-05347-x

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Cumin C, Huang YL, Rossdam C, Ruoff F, Céspedes SP, Liang CY, Lombardo FC, Coelho R, Rimmer N, Konantz M, López MN, Alam S, Schmidt A, Calabrese D, Fedier A, Vlajnic T, von Itzstein M, Templin M, Buettner FFR, et al. (2022). Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways. Cell Reports, 40(7), 111181. https://doi.org/10.1016/j.celrep.2022.111181

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Stark, Stefan G., Ficek, Joanna, Locatello, Francesco, Bonilla, Ximena, Chevrier, Stéphane, Singer, Franziska, Rätsch, Gunnar, Lehmann, Kjong-Van, Rudolf, Aebersold, Al-Quaddoomi Faisal, S., Jonas, Albinus, Ilaria, Alborelli, Sonali, Andani, Per-Olof, Attinger, Marina, Bacac, Daniel, Baumhoer, Beatrice, Beck-Schimmer, Niko, Beerenwinkel, Christian, Beisel, et al. (2020). SCIM: Universal single-cell matching with unpaired feature sets. Bioinformatics, 36, I919–I927. https://doi.org/10.1093/bioinformatics/btaa843

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Jacob, Francis, Alam, Shahidul, Konantz, Martina, Liang, Ching-Yeu, Kohler, Reto S., Everest-Dass, Arun V., Huang, Yen-Lin, Rimmer, Natalie, Fedier, Andre, Schötzau, Andreas, Lopez, Monica Nunez, Packer, Nicolle H., Lengerke, Claudia, & Heinzelmann-Schwarz, Viola. (2018). Transition of Mesenchymal and Epithelial Cancer Cells Depends on α1-4 Galactosyltransferase-Mediated Glycosphingolipids. Cancer Research, 78(11), 2952–2965. https://doi.org/10.1158/0008-5472.can-17-2223

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