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Dr. med. Dr. phil. Urs Fisch

Department of Clinical Research
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Peer-Reviewed Publication Types

Fisch, U. (2024). From Brain Function to Breathing: Examining the Impact of Atypical Sleep Patterns on Ventilator Weaning in Post-Critical Care. Chest, 165(5), 1031–1032. https://doi.org/10.1016/j.chest.2024.02.039
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Fisch, Urs, Kliem, Paulina, Grzonka, Pascale, & Sutter, Raoul. (2024). Performance of large language models on advocating the management of meningitis: a comparative qualitative study [Journal-article]. BMJ Health & Care Informatics, 31(1), e100978. https://doi.org/10.1136/bmjhci-2023-100978
Fisch, Urs, Kliem, Paulina, Grzonka, Pascale, & Sutter, Raoul. (2024). Performance of large language models on advocating the management of meningitis: a comparative qualitative study [Journal-article]. BMJ Health & Care Informatics, 31(1), e100978. https://doi.org/10.1136/bmjhci-2023-100978
Dittrich, Tolga D., Vock, Dominik, Fisch, Urs, Hert, Lisa, Baumann, Sira M., Kliem, Paulina S.C., Rüegg, Stephan, Marsch, Stephan, De Marchis, Gian Marco, & Sutter, Raoul. (2024). Efficacy and Tolerability of Intranasal Midazolam Administration for Antiseizure Treatment in Adults: A Systematic Review. Neurocritical Care. https://doi.org/10.1007/s12028-024-01971-x
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Fisch, Urs, Jünger, Anja L., Baumann, Sira M., Semmlack, Saskia, De Marchis, Gian Marco, Rüegg, Stephan J., Hunziker, Sabina, Marsch, Stephan, & Sutter, Raoul. (2024). Association between Dose Escalation of Anesthetics and Outcomes in Patients with Refractory Status Epilepticus. Neurology, 102, E207995. https://doi.org/10.1212/wnl.0000000000207995
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Fisch, U., Kliem, P., Grzonka, P., & Sutter, R. (2024). Performance of large language models on advocating the management of meningitis: a comparative qualitative stud [Journal-article]. BMJ health & care informatics, 31(1), e100978. https://doi.org/10.1136/bmjhci-2023-100978
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Berger, Sebastian, Kuster, Tobias, Sutter, Raoul, & Fisch, Urs. (2023). Neurological evolution of severe baclofen intoxication: From brain death mimic to recovered brain function. BMJ Case Reports, 16. https://doi.org/10.1136/bcr-2023-257391
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Brégère C, Fisch U, Halbeisen FS, Schneider C, Dittmar T, Stricker S, Aghlmandi S, & Guzman R. (2023). Doublecortin and Glypican-2 concentrations in the cerebrospinal fluid from infants are developmentally downregulated. PloS One, 18(2), e0279343. https://doi.org/10.1371/journal.pone.0279343
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Fisch, Urs, Jünger, Anja L, Baumann, Sira M, Semmlack, Saskia, De Marchis, Gian Marco, Hunziker, Sabina, RüeggFAES, Stephan, Marsch, Stephan, & Sutter, Raoul. (2023). Association Between Induced Burst-Suppression and Clinical Outcomes in Patients With Refractory Status Epilepticus: A 9-Year Cohort Study. Neurology, Ahead of print. https://doi.org/10.1212/wnl.0000000000207129
Fisch, Urs, Jünger, Anja L., Baumann, Sira M., Semmlack, Saskia, De Marchis, Gian Marco, Hunziker, Sabina, Rüegg, Stephan, Marsch, Stephan, & Sutter, Raoul. (2023). Association Between Induced Burst Suppression and Clinical Outcomes in Patients With Refractory Status Epilepticus: A 9-Year Cohort Study. Neurology, 100, E1955–E1966. https://doi.org/10.1212/wnl.0000000000207129
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Fisch Urs, & Sutter Raoul. (2023). Author Response: Association between Induced Burst Suppression and Clinical Outcomes in Patients with Refractory Status Epilepticus: A 9-Year Cohort Study. Neurology, 101, 283. https://doi.org/10.1212/wnl.0000000000207719
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Fisch, Urs, & Sutter, Raoul. (2023). Author Response: Association Between Induced Burst Suppression and Clinical Outcomes in Patients With Refractory Status Epilepticus: A 9-Year Cohort Study. Neurology, 101(6), 283. https://doi.org/10.1212/wnl.0000000000207719
Kubacka, Marta, Zietz, Annaelle, Schaedelin, Sabine, Polymeris, Alexandros A., Hert, Lisa, Lieb, Johanna, Wagner, Benjamin, Seiffge, David, Traenka, Christopher, Altersberger, Valerian L., Dittrich, Tolga, Fladt, Joachim, Fisch, Urs, Thilemann, Sebastian, De Marchis, Gian Marco, Gensicke, Henrik, Bonati, Leo H., Lyrer, Philippe, Engelter, Stefan T., & Peters, Nils. (2023). Global Cortical Atrophy Is Associated with an Unfavorable Outcome in Stroke Patients on Oral Anticoagulation. Cerebrovascular Diseases, 52, 495–502. https://doi.org/10.1159/000527739
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Maulucci, F., Disanto, G., Bianco, G., Pileggi, M., Fischer, U., Padlina, G., Strambo, D., Michel, P., Kahles, T., Nedeltchev, K., Fisch, U., Bonati, L., Kägi, G., Escribano Paredes, J.B., Carrera, E., Nyffeler, T., Bolognese, M., Wegener, S., Luft, A., et al. (2023). Endovascular therapy outcome in isolated posterior cerebral artery occlusion strokes: A multicenter analysis of the Swiss Stroke Registry. European Stroke Journal, 8, 575–580. https://doi.org/10.1177/23969873221150125
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Polymeris, Alexandros A., Karwacki, Grzegorz M., Siepen, Bernhard M., Schaedelin, Sabine, Tsakiris, Dimitrios A., Stippich, Christoph, Guzman, Raphael, Nickel, Christian H., Sprigg, Nikola, Kägi, Georg, Vehoff, Jochen, Barinka, Filip, Thilemann, Sebastian, Maurer, Marina, Wagner, Benjamin, Traenka, Christopher, Gensicke, Henrik, De Marchis, Gian Marco, Bonati, Leo H., et al. (2023). Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial. Stroke, 54, 2223–2234. https://doi.org/10.1161/strokeaha.123.042866
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Sutter, Raoul, Jünger, Anja L., Baumann, Sira M., Grzonka, Pascale, De Stefano, Pia, & Fisch, Urs. (2023). Balancing the risks and benefits of anesthetics in status epilepticus [Journal-article]. Epilepsy & Behavior, 138, 109027. https://doi.org/10.1016/j.yebeh.2022.109027
Sutter R, Jünger AL, Baumann SM, Grzonka P, De Stefano P, & Fisch U. (2023). Balancing the risks and benefits of anesthetics in status epilepticus. Epilepsy & Behavior : E&B, 138, 109027. https://doi.org/10.1016/j.yebeh.2022.109027
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Urs Fisch. (2023). Wenn das Hirn das Herz zum Stoppen bringt. Praxis. Schweizerische Rundschau Für Medizin, 112(10), 530.
Zietz, Annaelle, Polymeris, Alexandros A, Helfenstein, Fabrice, Schaedelin, Sabine, Hert, Lisa, Wagner, Benjamin, Seiffge, David J, Traenka, Christopher, Altersberger, Valerian L, Dittrich, Tolga, Kaufmann, Josefin, Ravanelli, Flavia, Fladt, Joachim, Fisch, Urs, Thilemann, Sebastian, De Marchis, Gian Marco, Gensicke, Henrik, Bonati, Leo H, Katan, Mira, et al. (2023). The impact of competing stroke etiologies in patients with atrial fibrillation. European Stroke Journal, 8, 703–711. https://doi.org/10.1177/23969873231185220
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Fisch, Urs, Jünger, Anja Lena, Hert, Lisa, Rüegg, Stephan, & Sutter, Raoul. (2022). Therapeutically induced EEG burst-suppression pattern to treat refractory status epilepticus-what is the evidence? Zeitschrift Für Epileptologie, ahead of print. https://doi.org/10.1007/s10309-022-00539-z
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Fisch, Urs, Jünger, Anja L., Hert, Lisa, Rüegg, Stephan, & Sutter, Raoul. (2022). Therapeutically induced EEG burst-suppression pattern to treat refractory status epilepticus—what is the evidence? [Review]. Zeitschrift fur Epileptologie, 35, 303–309. https://doi.org/10.1007/s10309-022-00539-z
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Polymeris, Alexandros A, Macha, Kosmas, Paciaroni, Maurizio, Wilson, Duncan, Koga, Masatoshi, Cappellari, Manuel, Schaedelin, Sabine, Zietz, Annaelle, Peters, Nils, Seiffge, David J, Haupenthal, David, Gassmann, Luise, De Marchis, Gian Marco, Wang, Ruihao, Gensicke, Henrik, Stoll, Svenja, Thilemann, Sebastian, Avramiotis, Nikolaos S, Bonetti, Bruno, et al. (2022). Oral Anticoagulants in the Oldest Old with Recent Stroke and Atrial Fibrillation. Annals of Neurology, 91, 78–88. https://doi.org/10.1002/ana.26267
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Sutter, Raoul, Jünger, Anja L, Baumann, Sira M, Grzonka, Pascale, De Stefano, Pia, & Fisch, Urs. (2022). Balancing the risks and benefits of anesthetics in status epilepticus. Epilepsy & Behavior : E&B, 109027. https://doi.org/10.1016/j.yebeh.2022.109027
Wagner, Benjamin, Hert, Lisa, Polymeris, Alexandros A., Schaedelin, Sabine, Lieb, Johanna M., Seiffge, David J., Traenka, Christopher, Thilemann, Sebastian, Fladt, Joachim, Altersberger, Valerian L., Zietz, Annaelle, Dittrich, Tolga D., Fisch, Urs, Gensicke, Henrik, De Marchis, Gian Marco, Bonati, Leo H., Lyrer, Philippe A., Engelter, Stefan T., & Peters, Nils. (2022). Impact of type of oral anticoagulants in patients with cerebral microbleeds after atrial fibrillation-related ischemic stroke or TIA: Results of the NOACISP-LONGTERM registry. Frontiers in Neurology, 13. https://doi.org/10.3389/fneur.2022.964723
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Fisch U, & Bonati L. (2021). Response to ‘Re. Risk of Stroke before Revascularisation in Patients with Symptomatic Carotid Stenosis: A Pooled Analysis of Randomised Controlled Trials’. (Patent No. 5). 62(5), Article 5. https://doi.org/10.1016/j.ejvs.2021.08.014
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Fisch U, von Felten S, Wiencierz A, Jansen O, Howard G, Hendrikse J, Halliday A, Fraedrich G, Eckstein HH, Calvet D, Bulbulia R, Becquemin JP, Algra A, Rothwell P, Ringleb P, Mas JL, Brown MM, Brott TG, Bonati LH, & Carotid Stenosis Trialists’ Collaboration. (2021). Editor’s Choice - Risk of Stroke before Revascularisation in Patients with Symptomatic Carotid Stenosis: A Pooled Analysis of Randomised Controlled Trials. European Journal of Vascular and Endovascular Surgery : The Official Journal of the European Society for Vascular Surgery, 61(6), 881–887. https://doi.org/10.1016/j.ejvs.2021.02.024
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Engelter, Stefan T, Traenka, Christopher, Gensicke, Henrik, Schaedelin, Sabine A, Luft, Andreas R, Simonetti, Barbara Goeggel, Fischer, Urs, Michel, Patrik, Sirimarco, Gaia, Kägi, Georg, Vehoff, Jochen, Nedeltchev, Krassen, Kahles, Timo, Kellert, Lars, Rosenbaum, Sverre, von Rennenberg, Regina, Sztajzel, Roman, Leib, Stephen L, Jung, Simon, et al. (2021). Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial. The Lancet. Neurology, 20(5), 341–350. https://doi.org/10.1016/s1474-4422(21)00044-2
Engelter, Stefan T, Traenka, Christopher, Gensicke, Henrik, Schaedelin, Sabine, Luft, Andreas R, Simonetti, Barbara Goeggel, Fischer, Urs, Fischer, Urs, Michel, Patrik, Sirimarco, Gaia, Kägi, Georg, Vehoff, Jochen, Nedeltchev, Krassen, Kahles, Timo, Kellert, Lars, Rosenbaum, Sverre, von Rennenberg, Regina, Sztajzel, Roman, Leib, Stephen L, et al. (2021). Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial. The Lancet Neurology, 20, 341–350. https://doi.org/10.1016/s1474-4422(21)00044-2
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Meya, Louisa, Polymeris, Alexandros A, Schaedelin, Sabine, Schaub, Fabian, Altersberger, Valerian L, Traenka, Christopher, Thilemann, Sebastian, Wagner, Benjamin, Fladt, Joachim, Hert, Lisa, Yoshimura, Sohei, Koga, Masatoshi, Zietz, Annaelle, Dittrich, Tolga, Fisch, Urs, Toyoda, Kazunori, Seiffge, David J, Peters, Nils, De Marchis, Gian Marco, et al. (2021). Oral Anticoagulants in Atrial Fibrillation Patients With Recent Stroke Who Are Dependent on the Daily Help of Others. Stroke, STROKEAHA120033862. https://doi.org/10.1161/strokeaha.120.033862
Meya, Louisa, Polymeris, Alexandros A., Schaedelin, Sabine, Schaub, Fabian, Altersberger, Valerian L., Traenka, Christopher, Thilemann, Sebastian, Wagner, Benjamin, Fladt, Joachim, Hert, Lisa, Yoshimura, Sohei, Koga, Masatoshi, Zietz, Annaelle, Dittrich, Tolga, Fisch, Urs, Toyoda, Kazunori, Seiffge, David J., Peters, Nils, De Marchis, Gian Marco, et al. (2021). Oral Anticoagulants in Atrial Fibrillation Patients with Recent Stroke Who Are Dependent on the Daily Help of Others. Stroke, 52, 3472–3481. https://doi.org/10.1161/strokeaha.120.033862
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Fisch U, Brégère C, Geier F, Chicha L, & Guzman R. (2020). Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia. Journal of Neuroinflammation, 17(1), 26. https://doi.org/10.1186/s12974-020-1706-y
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Evers KS, Huhn EA, Fouzas S, Barro C, Kuhle J, Fisch U, Bernasconi L, Lapaire O, & Wellmann S. (2019). Impact of parturition on maternal cardiovascular and neuronal integrity in a high risk cohort - a prospective cohort study. BMC Pregnancy and Childbirth, 19(1), 403. https://doi.org/10.1186/s12884-019-2570-6
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Roethlisberger M, Gut L, Zumofen DW, Fisch U, Boss O, Maldaner N, Croci DM, Taub E, Corti N, Burkhardt JK, Guzman R, Bozinov O, & Mariani L. (2018). Cerebral venous thrombosis requiring invasive treatment for elevated intracranial pressure in women with combined hormonal contraceptive intake: risk factors, anatomical distribution, and clinical presentation. Neurosurgical Focus, 45(1), E12. https://doi.org/10.3171/2018.4.focus1891
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Evers, Katrina Suzanne, Atkinson, Andrew, Barro, Christian, Fisch U, Pfister, Marc, Huhn, Evelyn A, Lapaire, Olav, Kuhle, Jens, & Wellmann, Sven. (2018). Neurofilament as Neuronal Injury Blood Marker in Preeclampsia. Hypertension (Dallas, Tex. : 1979), 71(6), 1178–1184. https://doi.org/10.1161/hypertensionaha.117.10314
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Depoorter A, Neumann RP, Barro C, Fisch U, Weber P, Kuhle J, & Wellmann S. (2018). Neurofilament Light Chain: Blood Biomarker of Neonatal Neuronal Injury. Frontiers in Neurology, 9, 984. https://doi.org/10.3389/fneur.2018.00984
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Brégère C, Fisch U, Sailer MH, Lieb WS, Chicha L, Goepfert F., Kremer T, & Guzman R. (2017). Neonatal hypoxia-ischemia in rat increases doublecortin concentration in the cerebrospinal fluid. The European Journal of Neuroscience, 46(2), 1758–1767. https://doi.org/10.1111/ejn.13612
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Seiffge, David J., Traenka, Christopher, Polymeris, Alexandros, Hert, Lisa, Fisch, Urs, Peters, Nils, De Marchis, Gian Marco, Guzman, Raphael, Nickel, Christian H., Lyrer, Philipp A., Bonati, Leo H., Tsakiris, Dimitrios, & Engelter, Stefan. (2017). Feasibility of rapid measurement of Rivaroxaban plasma levels in patients with acute stroke. Journal of Thrombosis and Thrombolysis, 43, 112–116. https://doi.org/10.1007/s11239-016-1431-7
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Rossi-Mossuti F, Fisch U, Schoettker P, Gugliotta M, Morard M, Schucht P, Schatlo B, Levivier M, Walder B, & Fandino J. (2016). Surgical Treatment of Severe Traumatic Brain Injury in Switzerland: Results from a Multicenter Study. Journal of Neurological Surgery. Part A, Central European Neurosurgery, 77(1), 36–45. https://doi.org/10.1055/s-0035-1563556
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Fisch U, Zehnder A, Hirt A, Niggli F, Simon A, Ozsahin H, Schlapbach L, & Ammann R. (2011). Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer. Swiss Medical Weekly, 141, w13191. https://doi.org/10.4414/smw.2011.13191
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Zehnder A, Fisch U, Hirt A, Niggli FK, Simon A, Ozsahin H, Schlapbach LJ, & Ammann RA. (2009). Prognosis in pediatric hematologic malignancies is associated with serum concentration of mannose-binding lectin-associated serine protease-2 (MASP-2). Pediatric Blood & Cancer, 53(1), 53–57. https://doi.org/10.1002/pbc.22028
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Schlapbach LJ, Aebi C, Fisch U, Ammann RA, Otth M, Bigler S, Nelle M, Berger S, & Kessler U. (2008). Higher cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis. Pediatric Research, 64(5), 562–566. https://doi.org/10.1203/pdr.0b013e3181841335
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Other Publications

Spöndlin, L., Hardmeier, M., Sutter, R., Lee, J. W., Rüegg, S., & Fisch, U. (2024). Electroencephalographic compatibility with fitness to drive: A nationwide survey among Swiss neurologists [Journal-article]. Epilepsia Open. https://doi.org/10.1002/epi4.13041
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Fisch, U., Juenger, A., Baumann, S. M., Marsch, S., Rüegg, S., & Sutter, R. (2022). WE-103. Burst suppression and intravenous anesthetic antiseizure drugs in patients with refractory status epilepticus in a tertiary medical care center [Journal-article]. Clinical Neurophysiology, 141, S56. https://doi.org/10.1016/j.clinph.2022.07.147
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Fisch Urs, Juenger Anja, Hert Lisa, Rüegg Stephan, & Sutter Raoul. (2022). Therapeutically induced EEG burst-suppression pattern to treat refractory status epilepticus – what is the evidence. Z. Epileptol. , 35(4), 303–309. https://doi.org/10.1007/s10309-022-00539-z
Fisch, Urs. (2021). Anspruch an die integrale Ausbildung zum Humanmediziner [Journal-article]. Schweizerische Ärztezeitung. https://doi.org/10.4414/saez.2021.20133
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Fisch, U., von Felten, S., Wiencierz, A., Jansen, O., Howard, G., Hendrikse, J., Halliday, A., Fraedrich, G., Eckstein, H.-H., Calvet, D., Bulbulia, R., Becquemin, J.-P., Algra, A., Rothwell, P., Ringleb, P., Mas, J.-L., Brown, M. M., Brott, T. G., & Bonati, L. H. (2021). Risk of Stroke before Revascularisation in Patients with Symptomatic Carotid Stenosis: A Pooled Analysis of Randomised Controlled Trials [Journal-article]. Journal of Vascular Surgery, 74(1), 338. https://doi.org/10.1016/j.jvs.2021.05.016
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Fisch, Urs, Baumann, Sira M., Semmlack, Saskia, Marsch, Stephan, Rüegg, Stephan, & Sutter, Raoul. (2021). Accuracy of Calculated Free Valproate Levels in Adult Patients With Status Epilepticus. Neurology, 96(1), e102–e110. https://doi.org/10.1212/wnl.0000000000011000
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Roethlisberger, Michel, Moffa, Giusi, Fisch, Urs, Wiggli, Benedikt, Schoen, Stephan, Kelly, Christopher, Leu, Severina, Croci, Davide, Zumofen, Daniel W., Cueni, Nadine, Nogarth, Danica, Schulz, Marianne, Bucher, Heiner C., Weisser-Rohacek, Maja, Wasner, Morten-Goetz, Widmer, Andreas F., & Mariani, Luigi. (2018). Effectiveness of a Chlorhexidine Dressing on Silver-coated External Ventricular Drain-associated Colonization and Infection: A Prospective Single-blinded Randomized Controlled Clinical Trial. Clinical Infectious Diseases, 67(12), 1868–1877. https://doi.org/10.1093/cid/ciy393
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Seiffge, David J., Traenka, Christopher, Polymeris, Alexandros A., Thilemann, Sebastian, Wagner, Benjamin, Hert, Lisa, Müller, Mandy D., Gensicke, Henrik, Peters, Nils, Nickel, Christian H., Stippich, Christoph, Sutter, Raoul, Marsch, Stephan, Fisch, Urs, Guzman, Raphael, Marchis, Gian Marco De, Lyrer, Philippe A., Bonati, Leo H., Tsakiris, Dimitrios A., & Engelter, Stefan T. (2017). Intravenous Thrombolysis in Patients with Stroke Taking Rivaroxaban Using Drug Specific Plasma Levels: Experience with a Standard Operation Procedure in Clinical Practice. Journal of Stroke, 19(3), 347–355. https://doi.org/10.5853/jos.2017.00395
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Sailer, Martin H., Sarvepalli, Durga, Bregere, Catherine, Fisch, Urs, Guentchev, Marin, Weller, Michael, Guzman, Raphael, Bettler, Bernhard, Ghosh, Arkasubhra, & Hutter, Gregor. (2016). An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery. Jove-Journal of Visualized Experiments, 114, 54018. https://doi.org/10.3791/54018
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Supplemental Publications

Rusche, Thilo, Yaldizli, Özgür, Galbusera, Riccardo, Mutke, Matthias, Halter, Jörg P, Lieb, Johanna, Matteazzi, Francesca, Stelmes, Anne, Bittner, Jan, Grzonka, Pascale, Frank, Nicole, Cordier, Dominik, Hench, Jürgen, Frank, Stephan, Hirsch, Hans H, Fischer, Urs, Kuhle, Jens, Sutter, Raoul, Rüegg, Stephan, & Fisch, Urs. (2024). Anti-GABA A receptor encephalitis 14 months after allogeneic haematopoietic stem-cell transplant for acute myeloid leukaemia. The Lancet, 403, 469–470. https://doi.org/10.1016/s0140-6736(23)02831-3
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