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Dr. med. Dr. phil. Urs Fisch

Department of Clinical Research
Profiles & Affiliations

My research interests focus on enhancing diagnostics and treatment for status epilepticus and severe brain damage.

Additionally, I investigate methods how to improve driving evaluation for people with epilepsy.

Selected Publications

Fisch, Urs, Jünger, Anja L., Baumann, Sira M., Semmlack, Saskia, De Marchis, Gian Marco, Rüegg, Stephan J., Hunziker, Sabina, Marsch, Stephan, & Sutter, Raoul. (2024). Association between Dose Escalation of Anesthetics and Outcomes in Patients with Refractory Status Epilepticus. Neurology, 102(2), E207995. https://doi.org/10.1212/WNL.0000000000207995

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Fisch, Urs, Jünger, Anja L., Baumann, Sira M., Semmlack, Saskia, De Marchis, Gian Marco, Hunziker, Sabina, Rüegg, Stephan, Marsch, Stephan, & Sutter, Raoul. (2023). Association Between Induced Burst Suppression and Clinical Outcomes in Patients With Refractory Status Epilepticus: A 9-Year Cohort Study. Neurology, 100(19), E1955–E1966. https://doi.org/10.1212/WNL.0000000000207129

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Fisch, Urs, Jünger, Anja L., Hert, Lisa, Rüegg, Stephan, & Sutter, Raoul. (2022). Therapeutically induced EEG burst-suppression pattern to treat refractory status epilepticus—what is the evidence? [Review]. Zeitschrift fur Epileptologie, 35, 303–309. https://doi.org/10.1007/s10309-022-00539-z

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Fisch, Urs, Baumann, Sira M., Semmlack, Saskia, Marsch, Stephan, Rüegg, Stephan, & Sutter, Raoul. (2021). Accuracy of Calculated Free Valproate Levels in Adult Patients With Status Epilepticus. Neurology, 96(1), e102–e110. https://doi.org/10.1212/wnl.0000000000011000

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Selected Projects & Collaborations

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Pupillometric Evaluation in Patients Declared Brain Dead (INSPECT) - a Prospective Quality Control Study

Research Project  | 4 Project Members

Objectives: The aim of the study is to verify the reliability of the current purely clinical examination of the pupils (without the support of a pupillometer) in the context of clinically suspected brain death, compared to the results of a non-invasive, automated, and highly precise monocular pupillometric examination.


Methods: This prospective quality control study will evaluate the reliability of the clinical exam regarding pupils' reaction to light (as performed by two board certified physicians in Neurology and/or Intensive Care Medicine) as recommended by the SAMW guidelines for brain death diagnosis (SAMW-guidelines) when compared to the results of a noninvasive automated and highly-precise pupillometry in adult patients with clinically suspected brain death. Automated pupillometric measurements will be performed by the PI (RS), or the co-investigator (Dr. Pascale Grzonka) using the NeurOptics® NPi®-200 pupillometer system immediately before and after the standardized diagnostic workup for suspected brain death. In addition, demographics, clinical characteristics , treatment and laboratory data from the patients examined will be anonymously collected.