Pediatric Pharmacometrics (PMX)-AI Research Group
The Pediatric PMX-AI Research Group at UKBB, DKF, University of Basel is inventing, translating, evaluating, and implementing intelligent digital health solutions and child-friendly formulations to improve and save lives of pediatric patients worldwide.
UKBB level – As a result of a strong partnership with pediatric endocrinology (Prof. Gabor Szinnai) the digital health project OptiThyDose was granted ~1.0M by BRCCH to develop and clinically evaluate clinical decision support tools for children with a thyroid disease (https://brc.ch/research/optithydose/).
University of Basel level – While mentoring several master students and six PhD students we have published more than 100 peer-reviewed papers in 2-3 years. We have strengthened our partnerships with the Department of Pharmaceutical Sciences (Prof. Joerg Huwyler, Prof. Christoph Meier) and Swiss TPH (Prof. Jennifer Keiser). The latest joint research project with Swiss TPH was granted ~0.8M by the Bill & Melina Gates Foundation.
National level – We lead SwissPedPha, serve in the SwissPedNet board and contribute to expert teams of SwissPedDose and PEDeDose. We partner with several Swiss research centers such as the SwissPedNet hub in Lucerne (Dr. Michael Buettcher).
International level – A joint project with the University of Oxford/MORU Tropical Health Network was launched to evaluate the novel, child-friendly formulation of ivermectin CHILD-IVITAB in children <15 kg (EPIC-15). EPIC-15 was granted ~0.5M by the Thrasher Research Fund.
Start-up companies – NeoPrediX AG was established to facilitate implementation of PMX-AI based digital health solutions in perinatal medicine (www.neopredix.com). Galvita AG was founded to bring child-friendly formulations such as CHILD-IVITAB to pediatric patients not just in Switzerland but worldwide, including low- and middle-income countries (www.galvita.com). Further, EqVita AG was recently founded to develop PMX-AI based decision support tools to facilitate personalized care of pediatric and adult patients worldwide.
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