MD PhD Alain Amstutz

Chiaborelli, Malena, Kopeka, Mamaswatsi, Sekhesa, Pontšo, Sehrt, Madeleine, Mohloanyane, Tsepang, Ballouz, Tala, Menges, Dominik, Brown, Jennifer A., Belus, Jennifer M., Gerber, Felix, Raeber, Fabian, Williams, Andréa, Jackson-Perry, David, Hyöky, Meri, Conserve, Donaldson F., Hampanda, Karen, Amstutz, Alain, Mohale, Itumeleng, Lebakeng, Thabo, et al. (2025). Hair salons as a promising space to provide HIV and sexual and reproductive health services for young women in Lesotho: a citizen scientist mixed-methods study [Journal-article]. BMC Public Health, 25(1). https://doi.org/10.1186/s12889-025-23435-3

Johnson, N. E., Falgas‐Bague, I., Chammartin, F., Gerber, F., Lee, T. T., Gupta, R., Mjadu, R., Nthunya, J., Mokebe, M., Makabateng, R., Sematle, M. P., Letsoela, P., Labhardt, N. D., Amstutz, A., & Belus, J. M. (2025). Mental health and substance use problems among adolescents in Lesotho: Prevalence, access to care, and association with lifestyle factors [Journal-article]. Journal of Research on Adolescence, 35(3). https://doi.org/10.1111/jora.70062

Taji Heravi, Ala, Gryaznov, Dmitry, Busse, Jason W., Schönenberger, Christof Manuel, von Niederhäusern, Belinda, Hausheer, Lena, Covino, Manuela, Schwenke, Johannes M., Epp, Selina, Griessbach, Alexandra, Chiaborelli, Malena, Agarwal, Arnav, Lohner, Szimonetta, Hirt, Julian, Schandelmaier, Stefan, Egli, Simon B., Makhele, Moshao Amos, Amstutz, Alain, Mertz, Dominik, et al. (2025). Metaresearch on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias. Journal of Clinical Epidemiology, 185. https://doi.org/10.1016/j.jclinepi.2025.111822

Gerber, Felix, Sanchez-Samaniego, Giuliana, Tahirsylaj, Thesar, Lejone, Thabo Ishmael, Lee, Tristan, Raeber, Fabian, Chitja, Mamakhala, Mathulise, Malebona, Kabi, Thuso, Mokaeane, Mosoetsi, Maphenchane, Malehloa, Molulela, Manthabiseng, Mota, Mota, Masike, Sesale, Bane, Matumaole, Makabateng, Retselisitsoe, Khomolishoele, Makhebe, Sematle, Mamoronts’Ane, Gupta, Ravi, et al. (2025). Cohort profile: The open, prospective Community-Based chronic Care Lesotho (ComBaCaL) cohort - Design, baseline chronic disease risk factors and hypertension and diabetes care cascades. BMJ Open, 15. https://doi.org/10.1136/bmjopen-2024-093852

Amstutz, A., Schandelmaier, S., Ewald, H., Speich, B., Schwenke, J. M., Schönenberger, C. M., Schobinger, S., Agoritsas, T., Tomashek, K. M., Nayak, S., Makowski, M., Morales-Ortega, A., Bernal-Bello, D., Pomponio, G., Ferrarini, A., Ghazaeian, M., Hall, F., Bond, S., García-Morales, M. T., et al. (2025). Effects of Janus kinase inhibitors in adults admitted to hospital due to COVID-19: a systematic review and individual participant data meta-analysis of randomised clinical trials [Journal-article]. The Lancet Respiratory Medicine, 13(6), 530–544. https://doi.org/10.1016/S2213-2600(25)00055-4

Pesonel, E., Laouénan, C., Guiraud, L., Bourner, J., Hoffmann, I., Molino, D., Tardivon, C., Bachelet, D., Mentré, F., Amstutz, A., Merson, L., Rojek, A., Cervantes Gonzalez, M., Antinori, A., Castagna, A., Nozza, S., Pourcher, V., Libois, A., Dunning, J., et al. (2025). Clinical Characterization and Outcomes of Human Clade IIb Mpox Virus Disease: A European Multicenter Mpox Observational Cohort Study (MOSAIC) [Journal-article]. Clinical Infectious Diseases, 80(5), 1060–1073. https://doi.org/10.1093/cid/ciae657

Mapesi, Herry, Rohacek, Martin, Vanobberghen, Fiona, Gupta, Ravi, Wilson, Herieth Ismael, Lukau, Blaise, Amstutz, Alain, Lyimo, Aza, Muhairwe, Josephine, Senkoro, Elizabeth, Byakuzana, Theonestina, Nkouabi, Jacqueline, Mbunda, Geofrey, Siru, Jamali, Tarr, Ayesha, Ramapepe, Elsie, Mphunyane, Madavida, Oehri, Johanna, Nemtsova, Valeriya, et al. (2025). Treatment Strategies to Control Blood Pressure in People with Hypertension in Tanzania and Lesotho: A Randomized Clinical Trial. JAMA Cardiology, 10(4), 321–333. https://doi.org/10.1001/jamacardio.2024.5124

Brown, Jennifer Anne, Motaboli, Lipontso, Lerotholi, Malebanye, Kohler, Maurus, Haenggi, Kathrin, Mokete, Moliehi, Chakela, Makobefo Gladys, Kao, Mpho, Kopo, Mathebe, Mokebe, Moleboheng, Urda, Lorena, Nsakala, Bienvenu Lengo, Lukau, Blaise, Ayakaka, Irene, Amstutz, Alain, Ehmer, Jochen, Klicpera, Anna, Klimkait, Thomas, Glass, Tracy, et al. (2025). Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2023 – cohort description, test volumes, predictors of viraemia and the road ahead [Journal-article]. BMJ Open, 15(2). https://doi.org/10.1136/bmjopen-2024-085404

Johnson, Natalie E., Belus, Jennifer M., Gerber, Felix, Lee, Tristan T., Ayakaka, Irene, Letsoela, Pearl, Molulela, Manthabiseng, Chammartin, Frédérique, Amstutz, Alain, & Labhardt, Niklaus D. (2025). Prevalence and factors associated with dementia in Lesotho: A cross-sectional, population-based study. Alzheimer’s and Dementia, 21(2). https://doi.org/10.1002/alz.14614

Audige, Annette, Amstutz, Alain, Schuurmans, Mace M., Amico, Patrizia, Braun, Dominique L., Stoeckle, Marcel P., Hasse, Barbara, Hage, Rene, Damm, Dominik, Tamm, Michael, Mueller, Nicolas J., Gunthard, Huldrych F., Koller, Michael T., Schonenberger, Christof M., Griessbach, Alexandra, Labhardt, Niklaus D., Kouyos, Roger D., Trkola, Alexandra, Huber, Michael, et al. (2025). Low agreement and frequent invalid controls in two SARS-CoV-2 T-cell assays in people with compromised immune function. PLoS ONE, 20(1 January). https://doi.org/10.1371/journal.pone.0317965

Jackson-Perry, David, & Amstutz, Alain. (2025). Should we be paying more attention to HIV and adult ADHD? Lancet HIV. https://doi.org/10.1016/S2352-3018(25)00235-8

Spaolonzi, Nicoló, Gupta, Ravi, Sanchez-Samaniego, Giuliana, Carter, Alexander, Tahirsylaj, Thesar, Raeber, Fabian, Mathulise, Malebona, Kabi, Thuso, Mokaeane, Mosoetsi, Maphenchane, Malehloa, Molulela, Manthabiseng, Khomolishoele, Makhebe, Mota, Mota, Masike, Sesale, Bane, Matumaole, Sematle, Mamoronts’ane Pauline, Makabateng, Retselisitsoe, Sao, Lebohang, Tlahali, Mosa, et al. (2025). Costs and Coverage of Community Health Worker-Led Hypertension and Diabetes Screening in Rural Lesotho: A Cohort Study with a Cost-Consequence Analysis. In SSRN. Elsevier. https://doi.org/10.2139/ssrn.5177608

Hampanda, K., Bolt, M., Nayame, L., Hamoonga, T., Sehrt, M., Thorne, J., Harrison, M., Pintye, J., Amstutz, A., Abuogi, L., & Mweemba, O. (2024). HIV Risk and Intention to use PrEP among Sexually Active Female University Students in Zambia: A Cross-Sectional Survey to Understand Influential Factors [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.12.12.24318948

Belus, Jennifer M., Johnson, Natalie E., Yoon, Grace H., Tschumi, Nadine, Lerotholi, Malebanye, Falgas-Bague, Irene, Lee, Tristan T., Letsoela, Pearl, Magidson, Jessica F., Amstutz, Alain, & Labhardt, Niklaus D. (2024). SMSs as an alternative to provider-delivered care for unhealthy alcohol use: study protocol for Leseli, an open-label randomised controlled trial of mhGAP-Remote vs mhGAP-Standard in Lesotho [Journal-article]. Trials, 25(1). https://doi.org/10.1186/s13063-024-08411-3

Gerber, Felix, Gupta, Ravi, Lejone, Thabo Ishmael, Tahirsylaj, Thesar, Lee, Tristan, Sanchez-Samaniego, Giuliana, Kohler, Maurus, Haldemann, Maria-Inés, Raeber, Fabian, Chitja, Mamakhala, Mathulise, Malebona, Kabi, Thuso, Mokaeane, Mosoetsi, Maphenchane, Malehloa, Molulela, Manthabiseng, Khomolishoele, Makhebe, Mota, Mota, Masike, Sesale, Bane, Matumaole, et al. (2024). Community-based management of arterial hypertension and cardiovascular risk factors by lay village health workers for people with controlled and uncontrolled blood pressure in rural Lesotho: joint protocol for two cluster-randomized trials within the ComBaCaL cohort study (ComBaCaL aHT Twic 1 and ComBaCaL aHT TwiC 2). Trials, 25(1). https://doi.org/10.1186/s13063-024-08226-2

Griessbach, Alexandra, Speich, Benjamin, Amstutz, Alain, Hausheer, Lena, Covino, Manuela, Wnfried Ramirez, Hillary, Schandelmaier, Stefan, Taji Heravi, Ala, Treweek, Shaun, Schwenkglenks, Matthias, Briel, Matthias, von Niederhäusern, Belinda, Hemkens, Lars G., Kasenda, Benjamin, Pauli-Magnus, Christiane, & McLennan, Stuart. (2024). Resource use and costs of investigator-sponsored randomized clinical trials in Switzerland, Germany, and the United Kingdom: a metaresearch study. Journal of Clinical Epidemiology, 176. https://doi.org/10.1016/j.jclinepi.2024.111536

Schönenberger, Christof M., Gerber, Felix, & Amstutz, Alain. (2024). Trials within cohorts (TwiCs): A novel design to efficiently embed pragmatic randomised trials into cohort studies [Journal-article]. Regulatory Affairs Watch, 9, 34–39. https://doi.org/10.54920/scto.2024.rawatch.9.34

Firima, Emmanuel, Ntsoaki, Rameno, Lukau, Blaise, Tlahali, Mosa, Gonzalez Fernandez, Lucia, Manthabiseng, Molulela, Sematle, Mamoronts’ane P, Bane, Matumaole, Khomolishoele, Makhebe, Ikhetheleng, Leisa, Retselisitsoe, Lefokosane, Gupta, Ravi, McCrosky, Stephen, Lee, Tristan, Chammartin, Frederique, Weisser, Maja, Labhardt, Niklaus D, & Amstutz, Alain. (2024). Prevalence of hepatitis B virus infection and treatment eligibility in Lesotho, Southern Africa: a population-based cross-sectional study with case-based follow-up [Journal-article]. BMJ Public Health, 2(2), e001195. https://doi.org/10.1136/bmjph-2024-001195

Jackson-Perry, David, Cart-Richter, Ellen, Haerry, David, Ahmeti, Lindrit, Bieri, Annatina, Calmy, Alexandra, Ballif, Marie, Pasin, Chloé, Notter, Julia, & Amstutz, Alain. (2024). Patient and public involvement in HIV research: a mapping review and development of an online evidence map [Short Report]. Journal of the International AIDS Society, 27(11). https://doi.org/10.1002/jia2.26385

Amstutz, Alain, Chammartin, Frédérique, Audigé, Annette, Eichenberger, Anna L., Braun, Dominique L., Amico, Patrizia, Stoeckle, Marcel P., Hasse, B., Papadimitriou-Olivgeris, Matthaios, Manuel, Oriol, Bongard, Cédric, Schuurmans, Macé, Hage, René, Damm, Dominik, Tamm, Michael, Mueller, Nicolas J., Rauch, A., Günthard, H.F., Koller, Michael T., et al. (2024). Antibody and T-Cell Response to Bivalent Booster SARS-CoV-2 Vaccines in People With Compromised Immune Function: COVERALL-3 Study. Journal of Infectious Diseases, 230(4), e847–e859. https://doi.org/10.1093/infdis/jiae291

Amstutz, Alain, Schönenberger, Christof M., Speich, Benjamin, Griessbach, Alexandra, Schwenke, Johannes M., Glasstetter, Jan, James, Sophie, Verkooijen, Helena M., Nickolls, Beverley, Relton, Clare, Hemkens, Lars G., Chammartin, Frédérique, Gerber, Felix, Labhardt, Niklaus D., Schandelmaier, Stefan, & Briel, Matthias. (2024). Characteristics, consent patterns, and challenges of randomized trials using the Trials within Cohorts (TwiCs) design - A scoping review. Journal of Clinical Epidemiology, 174. https://doi.org/10.1016/j.jclinepi.2024.111469

Fernández, Lucia González, Firima, Emmanuel, Gupta, Ravi, Sematle, Mamoronts’ane Pauline, Khomolishoele, Makhebe, Molulela, Manthabiseng, Bane, Matumaole, Tlahali, Mosa, McCrosky, Stephen, Lee, Tristan, Chammartin, Frédérique, Seelig, Eleonora, Gerber, Felix, Lejone, Thabo Ishmael, Ayakaka, Irene, Labhardt, Niklaus Daniel, & Amstutz, Alain. (2024). Awareness, treatment, and control among adults living with arterial hypertension or diabetes mellitus in two rural districts in Lesotho. PLOS Global Public Health, 4(9). https://doi.org/10.1371/journal.pgph.0003721

Gerber, F., Sanchez-Samaniego, G., Tahirsylaj, T., Lejone, T. I., Lee, T., Raeber, F., Chitja, M., Mathulise, M., Kabi, T., Mokaeane, M., Maphenchane, M., Khomolishoele, M., Mota, M., Masike, S., Bane, M., Sematle, M. P., Molulela, M., Makabateng, R., Gupta, R., et al. (2024). Cohort profile: design, sociodemographic characteristics, chronic disease risk factors, and baseline hypertension and diabetes care cascades of the open, prospective Community-Based chronic disease Care Lesotho (ComBaCaL) cohort [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.09.18.24313892

Abela, Irene A, Chammartin, Frédérique, Amstutz, Alain, Surial, Bernard, Ballif, Marie, Marzolini, Catia, Aebi-Popp, Karoline, Notter, Julia, Segeral, Olivier, Stoeckle, Marcel, Cavassini, Matthias, Bernasconi, Enos, Günthard, Huldrych F, Kouyos, Roger D, & Pasin, Chloé. (2024). Gender Disparities in Statin Prescriptions in People With HIV With Low/Moderate to High Cardiovascular Risk. Open Forum Infectious Diseases, 11(9). https://doi.org/10.1093/ofid/ofae502

Brown, Jennifer Anne, Ringera, Isaac Kaumbuthu, Luoga, Ezekiel, Bresser, Moniek, Mothobi, Buoang, Kabundi, Lorraine, Ilunga, Mulume, Mokhele, Kuena, Isaac, Andreas Boy, Tsoaeli, Ntsepiseng, Mbaya, Thomas, Simba, Brenda, Mayogu, Kasasi, Mabula, Elizabeth, Cheleboi, Molisana, Molatelle, Mamello, Kimera, Namvua, Mollel, Getrud Joseph, Sando, David, et al. (2024). Resistance-informed versus empirical management of viraemia in children and adolescents with HIV in Lesotho and Tanzania (GIVE MOVE trial): a multisite, open-label randomised controlled trial [Journal-article]. The Lancet Global Health, 12(8), e1312–e1322. https://doi.org/10.1016/s2214-109x(24)00183-9

González Fernández, Lucia, Firima, Emmanuel, Gupta, Ravi, Sematle, Mamoronts’ane Pauline, Khomolishoele, Makhebe, Molulela, Manthabiseng, Bane, Matumaole, Meli, Raphaela, Tlahali, Mosa, Lee, Tristan, Chammartin, Frederique, Gerber, Felix, Lejone, Thabo Ishmael, Ayakaka, Irene, Weisser, Maja, Amstutz, Alain, & Labhardt, Niklaus Daniel. (2024). Prevalence and determinants of cardiovascular risk factors in Lesotho: a population-based survey. International Health, 16(3), 313–324. https://doi.org/10.1093/inthealth/ihad058

González Fernández, Lucia, Firima, Emmanuel, Gupta, Ravi, Sematle, Mamoronts’ane Pauline, Khomolishoele, Makhebe, Molulela, Manthabiseng, Bane, Matumaole, Meli, Raphaela, Tlahali, Mosa, Lee, Tristan, Chammartin, Frédérique, Gerber, Felix, Lejone, Thabo Ishmael, Ayakaka, Irene, Weisser, Maja, Amstutz, Alain, & Labhardt, Niklaus Daniel. (2024). Prevalence and determinants of cardiovascular risk factors in Lesotho: a population-based survey [Journal-article]. International Health, 16(3), 313–324. https://doi.org/10.1093/inthealth/ihad058

Gerber, F., Gupta, R., Lejone, T. I., Tahirsylaj, T., Lee, T., Sanchez-Samaniego, G., Kohler, M., Haldemann, M.-I., Raeber, F., Chitja, M., Mathulise, M., Khabi, T., Mokaeane, M., Maphenchane, M., Molulela, M., Khomolishoele, M., Mota, M., Masike, S., Bane, M., et al. (2024, April 9). Community-based management of arterial hypertension and cardiovascular risk factors by lay village health workers for people with controlled and uncontrolled blood pressure in rural Lesotho: Joint protocol for two cluster-randomized trials within the ComBaCaL cohort study (ComBaCaL aHT Twic 1 & ComBaCaL aHT TwiC 2) [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-3805346/v1

Griessbach, Alexandra, Schönenberger, Christof Manuel, Taji Heravi, Ala, Gloy, Viktoria, Agarwal, Arnav, Hallenberger, Tim Jonas, Schandelmaier, Stefan, Janiaud, Perrine, Amstutz, Alain, Covino, Manuela, Mall, David, Speich, Benjamin, & Briel, Matthias. (2024). Characteristics, Progression, and Output of Randomized Platform Trials: A Systematic Review. JAMA Network Open, 7, E243109. https://doi.org/10.1001/jamanetworkopen.2024.3109

Brown, Jennifer A., Motaboli, Lipontso, Lerotholi, Malebanye, Kohler, Maurus, Hänggi, Kathrin, Mokete, Moliehi, Chakely, Makobefo G., Kao, Mpho, Kopo, Mathebe, Mokebe, Moleboheng, Nsakala, Bienvenu L., Lukau, Blaise, Ayakaka, Irene, Amstutz, Alain, Ehmer, Jochen, Klimkait, Thomas, Glass, Tracy R., Muhairwe, Josephine, Chammartin, Frédérique, et al. (2024). Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2022 - cohort description, test volumes, predictors of viraemia, and the road ahead [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.03.12.24304025

Firima, E., Gonzalez, L., Manthabiseng, M., Bane, M., Lukau, B., Leigh, B., Kaufmann, B. A., Weisser, M., Amstutz, A., Tromp, J., Labhardt, N. D., & Burkard, T. (2024). Implementing focused echocardiography and AI-supported analysis in a population-based survey in Lesotho: implications for community-based cardiovascular disease care models. Hypertension Research, 47(3), 708–713. https://doi.org/10.1038/s41440-023-01559-6

Bresser, Moniek, Erhardt, Rahel Milena, Shanaube, Kwame, Simwinga, Musonda, Mahlatsi, Palesa Agnes, Belus, Jennifer, Schaap, Albertus, Amstutz, Alain, Gachie, Thomas, Glass, Tracy Renée, Kangololo, Bxyn, John’Mota, Floyd, Sian, Katende, Bulemba, Klinkenberg, Eveline, Ayles, Helen, Reither, Klaus, & Ruperez, Maria. (2024). Evaluation of COVID-19 antigen rapid diagnostic tests for self-testing in Lesotho and Zambia. PLoS ONE, 19(2 February). https://doi.org/10.1371/journal.pone.0280105

Chammartin, Frédérique, Griessbach, Alexandra, Kusejko, Katharina, Audigé, Annette, Epp, Selina, Stoeckle, Marcel P., Eichenberger, Anna L., Amstutz, Alain, Schoenenberger, Christof M., Hasse, Barbara, Braun, Dominique L., Rauch, Andri, Trkola, Alexandra, Briel, Matthias, Bucher, Heiner C., Günthard, Huldrych F., Speich, Benjamin, & Abela, Irene A. (2024). Bridging the gap: identifying factors impacting mRNA severe acute respiratory syndrome coronavirus 2 vaccine booster response in people with HIV-1. Aids, 38(2), 217–222. https://doi.org/10.1097/qad.0000000000003751

Gerber, Felix, Semphere, Robina, Lukau, Blaise, Mahlatsi, Palesa, Mtenga, Timeo, Lee, Tristan, Kohler, Maurus, Glass, Tracy Renée, Amstutz, Alain, Molatelle, Mamello, MacPherson, Peter, Marake, Nthuseng Bridgett, Nliwasa, Marriot, Ayakaka, Irene, Burke, Rachael, & Labhardt, Niklaus. (2024). Same-day versus rapid ART initiation in HIV-positive individuals presenting with symptoms of tuberculosis: Protocol for an open-label randomized non-inferiority trial in Lesotho and Malawi. PLoS ONE, 19(2 Febuary). https://doi.org/10.1371/journal.pone.0288944

Amstutz, A., Schandelmaier, S., Ewald, H., Speich, B., Schwenke, J. M., Schönenberger, C., Schobinger, S., Agoritsas, T., Tomashek, K. M., Nayak, S. U., Makowski, M., Morales-Ortega, A., Bernal-Bello, D., Pomponio, G., Ferrarini, A., Ghazaeian, M., Hall, F., Bond, S., García-Morales, M. T., et al. (2024). Effects of Jak Inhibitors in Adults Hospitalized Due to Covid-19: A Systematic Review and Individual Participant Data Meta-Analysis of Randomized Clinical Trials [Posted-content]. Elsevier BV. https://doi.org/10.2139/ssrn.4974193

Fernández, Lucia González, Yoon, Grace H., Firima, Emmanuel, Gupta, Ravi, Sematle, Mamoronts’ane Pauline, Khomolishoele, Makhebe, Molulela, Manthabiseng, Bane, Matumaole, Tlahani, Mosa, Lee, Tristan T., Chammartin, Frédérique, Gerber, Felix, Lejone, Thabo, Ayakaka, Irene, Labhardt, Niklaus Daniel, Amstutz, Alain, & Belus, Jennifer M. (2024). Prevalence of Mental Health and Substance use Problems and Awareness of Need for Services in Lesotho: Results from a Population-Based Survey. International Journal of Mental Health and Addiction. https://doi.org/10.1007/s11469-024-01309-w

Gerber, Felix, Tahirsylaj, Thesar, Lejone, Thabo Ishmael, Lee, Tristan, Sanchez-Samaniego, Giuliana, Raeber, Fabian, Masike, Sesale, Gupta, Ravi, Molulela, Manthabiseng, Khomolishoele, Makhebe, Mota, Mota, Bane, Matumaole, Sematle, Mamoronts’ane Pauline, Makabateng, Retselisitsoe, Browne, Jason Immanuel, Wittwer, Jonas, Basler, Dave Brian, Kindler, Kevin, Labhardt, Niklaus Daniel, & Amstutz, Alain. (2024). eConsent administered by Community Health Workers in a study using the Trials within Cohorts (TwiCs) design—Experiences from the Community-Based chronic Care Lesotho (ComBaCaL) project. Digital Health, 10. https://doi.org/10.1177/20552076241288757

Manyara, Anthony Muchai, Davies, Philippa, Stewart, Derek, Weir, Christopher J, Young, Amber E, Blazeby, Jane, Butcher, Nancy J, Bujkiewicz, Sylwia, Chan, An-Wen, Dawoud, Dalia, Offringa, Martin, Ouwens, Mario, Hróbjartssson, Asbjørn, Amstutz, Alain, Bertolaccini, Luca, Bruno, Vito Domenico, Devane, Declan, Faria, Christina D C M, Gilbert, Peter B, et al. (2024). Reporting of surrogate endpoints in randomised controlled trial protocols (SPIRIT-Surrogate): extension checklist with explanation and elaboration. Bmj, 386, 19. https://doi.org/10.1136/bmj-2023-078525

Manyara, Anthony Muchai, Davies, Philippa, Stewart, Derek, Weir, Christopher J, Young, Amber E, Blazeby, Jane, Butcher, Nancy J, Bujkiewicz, Sylwia, Chan, An-Wen, Dawoud, Dalia, Offringa, Martin, Ouwens, Mario, Hróbjartssson, Asbjørn, Amstutz, Alain, Bertolaccini, Luca, Bruno, Vito Domenico, Devane, Declan, Faria, Christina D C M, Gilbert, Peter B, et al. (2024). Reporting of surrogate endpoints in randomised controlled trial reports (CONSORT-Surrogate): Extension checklist with explanation and elaboration. Bmj, 386, 18. https://doi.org/10.1136/bmj-2023-078524

Raeber, Fabian, Haldemann, Maria-Inés, Ray, Somidha, Huber, Jacqueline, Firima, Emmanuel, Fernandez, Lucia Gonzalez, Amstutz, Alain, Gerber, Felix, Labhardt, Niklaus D., & Belus, Jennifer M. (2024). Community-based models of care for adolescent and adult depression, suicidal behavior, anxiety, trauma, and substance use in Africa: a scoping review. Frontiers in Psychology, 15. https://doi.org/10.3389/fpsyg.2024.1241403

Firima, Emmanuel, Gonzalez, Lucia, Khan, Moazziz Ali, Manthabiseng, Molulela, Sematle, Mamoronts’sane P., Bane, Matumaole, Khomolishoele, Makhebe, Leisa, Ikhetheleng, Retselisitsoe, Lefokotsane, Burkard, Thilo, Seelig, Eleonara, Lee, Tristan, Chammartin, Frédérique, Gupta, Ravi, Leigh, Bailah, Weisser, Maja, Amstutz, Alain, Amstutz, Alain, & Labhardt, Niklaus Daniel. (2023). High Rates of Undiagnosed Target Organ Damage Among Adults with Elevated Blood Pressure or Diabetes Mellitus in a Community-Based Survey in Lesotho. Journal of Epidemiology and Global Health, 13(4), 857–869. https://doi.org/10.1007/s44197-023-00158-5

Gerber, Felix, Gupta, Ravi, Lejone, Thabo Ishmael, Tahirsylaj, Thesar, Lee, Tristan, Kohler, Maurus, Haldemann, Maria Ines, Räber, Fabian, Chitja, Mamakhala, Manthabiseng, Molulela, Khomolishoele, Makhebe, Mota, Mota, Bane, Matumaole, Sematle, Pauline Mamorontsane, Makabateng, Retselisitsoe, Mphunyane, Madavida, Phaaroe, Sejojo, Basler, Dave, Kindler, Kevin, et al. (2023). Community-based type 2 diabetes care by lay village health workers in rural Lesotho: protocol for a cluster-randomized trial within the ComBaCaL cohort study (ComBaCaL T2D TwiC). Trials, 24(1). https://doi.org/10.1186/s13063-023-07729-8

Troseid M., Arribas J.R., Assoumou L., Holten A.R., Poissy J., Terzic V., Mazzaferri F., Bano J.R., Eustace J., Hites M., Joannidis M., Paiva J.-A., Reuter J., Puntmann I., Patrick-Brown T.D.J.H., Westerheim E., Nezvalova-Henriksen K., Beniguel L., Dahl T.B., et al. (2023). Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial. Critical Care, 27(1). https://doi.org/10.1186/s13054-022-04205-8

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Firima, Emmanuel, Gonzalez, Lucia, Ursprung, Fabiola, Robinson, Elena, Huber, Jacqueline, Belus, Jennifer M., Raeber, Fabian, Gupta, Ravi, Deen, Gibrilla F., Amstutz, Alain, Leigh, Bailah, Weisser, Maja, Weisser, Maja, & Labhardt, Niklaus Daniel. (2023). Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: A scoping review. PLoS ONE, 18(11 November). https://doi.org/10.1371/journal.pone.0278353

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Simwinga, Musonda, Mahlatsi, Palesa A., Molale, Masemote, Witola, Gracious, Mshanga, Isaac, Katende, Bulemba, Amstutz, Alain, Reither, Klaus, Shanaube, Kwame, Motlomelo, Masetsibi, Bond, Virginia, & Belus, Jennifer M. (2023). Facilitators and barriers to COVID-19 testing in community and clinical settings: Lessons learned from Lesotho and Zambia [Journal-article]. PLOS Global Public Health, 3(10), e0002430. https://doi.org/10.1371/journal.pgph.0002430

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Fernández, Lucia González, Firima, Emmanuel, Gupta, Ravi, Sematle, Mamoronts’ane, Khomolishoele, Makhebe, Molulela, Manthabiseng, Bane, Matumaole, Tlahali, Mosa, McCrosky, Stephen, Lee, Tristan, Chammartin, Frédérique, Seelig, Eleonora, Gerber, Felix, Lejone, Thabo Ishmael, Ayakaka, Irene, Labhardt, Niklaus Daniel, & Amstutz, Alain. (2023). Awareness, treatment, and control among adults living with arterial hypertension or diabetes mellitus in two rural districts in Lesotho [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-3189573/v1

Gerber, F., Semphere, R., Lukau, B., Mahlatsi, P., Mtenga, T., Lee, T., Kohler, M., Glass, T. R., Amstutz, A., Molatelle, M., MacPherson, P., Marake, N. B., Nliwasa, M., Ayakaka, I., Burke, R., & Labhardt, N. (2023, July 12). Same-day versus rapid ART initiation in HIV-positive individuals presenting with symptoms of tuberculosis: protocol for an open-label randomized non-inferiority trial in Lesotho and Malawi [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2023.07.10.23292457

Amstutz, Alain, Speich, Benjamin, Mentré, France, Rueegg, Corina Silvia, Belhadi, Drifa, Assoumou, Lambert, Burdet, Charles, Murthy, Srinivas, Dodd, Lori Elizabeth, Wang, Yeming, Tikkinen, Kari A O, Ader, Florence, Hites, Maya, Bouscambert, Maude, Trabaud, Mary Anne, Fralick, Mike, Lee, Todd C, Pinto, Ruxandra, Barratt-Due, Andreas, et al. (2023). Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials. The Lancet Respiratory Medicine, 11(5), 453–464. https://doi.org/10.1016/S2213-2600(22)00528-8

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Firima, E., Retselisitsoe, L., Leisa, I., Manthabiseng, M., Sematle, M. P., Bane, M., Khomolishoele, M., Gonzalez, L., Gupta, R., McCrosky, S., Lee, T., Chammartin, F., Leigh, B., Weisser, M., Amstutz, A., Burkard, T., & Labhardt, N. D. (2023). Head-to-head comparison of the WHO STEPwise approach with immediate unattended and delayed unattended automated blood pressure measurements during household-based screening: a diagnostic accuracy study in Lesotho. EClinicalMedicine, 63, 102197. https://doi.org/10.1016/j.eclinm.2023.102197

Katende, B., Bresser, M., Kamele, M., Chere, L., Tlahali, M., Erhardt, R. M., Muhairwe, J., Ayakaka, I., Glass, T. R., Ruhwald, M., van Ginneken, B., Murphy, K., de Vos, M., Amstutz, A., Mareka, M., Mooko, S. M., Reither, K., & González Fernández, L. (2023). Impact of a multi-disease integrated screening and diagnostic model for COVID-19, TB, and HIV in Lesotho. PLOS Glob Public Health, 3(8), e0001488. https://doi.org/10.1371/journal.pgph.0001488

Kopo, M., Lejone, T. I., Tschumi, N., Glass, T. R., Kao, M., Brown, J. A., Seiler, O., Muhairwe, J., Moletsane, N., Labhardt, N. D., & Amstutz, A. (2023). Effectiveness of a peer educator-coordinated preference-based differentiated service delivery model on viral suppression among young people living with HIV in Lesotho: the PEBRA cluster-randomized trial. PLOS Medicine, 20(1), e1004150. https://doi.org/10.1371/journal.pmed.1004150

Labhardt, N. D., González Fernández, L., Katende, B., Muhairwe, J., Bresser, M., Amstutz, A., Glass, T. R., Ruhwald, M., Sacks, J. A., Escadafal, C., Mareka, M., Mooko, S. M., de Vos, M., & Reither, K. (2023). Head-to-head comparison of nasal and nasopharyngeal sampling using SARS-CoV-2 rapid antigen testing in Lesotho. PLoS One, 18(3), e0278653. https://doi.org/10.1371/journal.pone.0278653

Seiler, O., Kopo, M., Kao, M., Lejone, T. I., Tschumi, N., Glass, T. G., Brown, J. A., Labhardt, N. D., & Amstutz, A. (2023). HIV care preferences among young people living with HIV in Lesotho: a secondary data analysis of the PEBRA cluster randomized trial. AIDS Research and Treatment, 2023, 8124192. https://doi.org/10.1155/2023/8124192

Bresser, M., Erhardt, R. M., Shanaube, K., Simwinga, M., Mahlatsi, P. A., Belus, J., Schaap, A., Amstutz, A., Gachie, T., Glass, T. R., Kangolo, B., ’Mota, M. J., Floyd, S., Katende, B., Klinkenberg, E., Ayles, H., Reither, K., & Ruperez, M. (2022, December 23). Evaluation of Covid-19 Ag-RDTs self-testing in Lesotho and Zambia [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.12.21.22283827

Katende, B., Bresser, M., Kamele, M., Chere, L., Tlahali, M., Erhardt, R. M., Muhairwe, J., Ayakaka, I., Glass, T. R., Ruhwald, M., van Ginneken, B., Murphy, K., de Vos, M., Amstutz, A., Mareka, M., Mooko, S. M., Labhardt, N. D., Reither, K., & González Fernández, L. (2022, December 22). Impact of a multi-disease integrated screening and diagnostic model for COVID-19, TB, and HIV in Lesotho [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.12.20.22283748

Ndongala NJ, Maepa C, Nyondo E, Amstutz A, & du Reau de la Gaignonnière B. (2022). Etiology, characteristics and occurrence of heart diseases in rural Lesotho (ECHOLesotho): A retrospective echocardiography cohort study. PLoS ONE, 17(12 December), e0278406. https://doi.org/10.1371/journal.pone.0278406

Firima, E., Gonzalez, L., Ursprung, F., Robinson, E., Huber, J., Belus, J. M., Raeber, F., Gupta, R., Deen, G. F., Amstutz, A., Leigh, B., Weisser, M., & Labhardt, N. D. (2022, November 17). Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: a scoping review [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.11.17.22282376

Mohloanyane T, Olivier D, Labhardt ND, & Amstutz A. (2022). Recent HIV infections among newly diagnosed individuals living with HIV in rural Lesotho: Secondary data from the VIBRA cluster-randomized trial. PLoS ONE, 17(11 November), e0277812. https://doi.org/10.1371/journal.pone.0277812

Seiler, Olivia, Kopo, Mathebe, Kao, Mpho, Lejone, Thabo Ishmael, Tschumi, Nadine, Glass, Tracy Renée, Brown, Jennifer Anne, Labhardt, Niklaus Daniel, & Amstutz, Alain. (2022). HIV care preferences among young people living with HIV in Lesotho: A secondary data analysis of the PEBRA cluster randomized trial [Posted-content]. In medRxiv. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.07.29.22278205

Brown, J. A., Nsakala, B. L., Mokhele, K., Rakuoane, I., Muhairwe, J., Glass, T. R., Amstutz, A., Tschumi, N., Belus, J. M., Klimkait, T., & Labhardt, N. D. (2022). Dolutegravir in real life: self-reported mental and physical health outcomes after transitioning from efavirenz- to dolutegravir-based antiretroviral therapy in a prospective cohort study in Lesotho. HIV Medicine, 24(2), 153–162. https://doi.org/10.1111/hiv.13352

Brown, Jennifer A., Nsakala, Bienvenu L., Mokhele, Kuena, Rakuoane, Itumeleng, Muhairwe, Josephine, Urda, Lorena, Amstutz, Alain, Tschumi , Nadine, Klimkait, Thomas, & Labhardt, Niklaus D. (2022). Viral suppression after transition from nonnucleoside reverse transcriptase inhibitor- to dolutegravir-based antiretroviral therapy: a prospective cohort study in Lesotho (DO-REAL study). HIV medicine, 23(3), 287–293. https://doi.org/10.1111/hiv.13189

Fernández, L. G., Firima, E., RObinson, E., Ursprung, F., Huber, J., Amstutz, A., Gupta, R., Gerber, F., Mokhohlane, J., Lejone, T., Ayakaka, I., Xu, H., & Labhardt, N. D. (2022). Correction: Community-based care models for arterial hypertension management in non-pregnant adults in sub-Saharan Africa: a literature scoping review and framework for designing chronic services. BMC Public Health, 22(1), 1640. https://doi.org/10.1186/s12889-022-13988-y

Firima, Emmanuel, Gonzalez, Lucia, Huber, Jacqueline, Belus, Jennifer M., Raeber, Fabian, Gupta, Ravi, Mokhohlane, Joalane, Mphunyane, Madavida, Amstutz, Alain, & Labhardt, Niklaus Daniel. (2022). Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: a scoping review protocol. F1000Research, 10, 535. https://doi.org/10.12688/f1000research.52114.2

González Fernández, L., Firima, E., Robinson, E., Ursprung, F., Huber, J., Amstutz, A., Gupta, R., Gerber, F., Mokhohlane, J., Lejone, T., Ayakaka, I., Xu, H., & Labhardt, N. D. (2022). Community-based care models for arterial hypertension management in non-pregnant adults in sub-Saharan Africa: a literature scoping review and framework for designing chronic services. BMC Public Health, 22, 1126. https://doi.org/10.1186/s12889-022-13467-4

Gryaznov, D., von Niederhäusern, B., Speich, B., Kasenda, B., Ojeda-Ruiz, E., Blümle, A., Schandelmaier, S., Mertz, D., Odutayo, A., Tomonaga, Y., Amstutz, A., Pauli-Magnus, C., Gloy, V., Lohner, S., Bischoff, K., Wollmann, K., Rehner, L., Meerpohl, J. J., Nordmann, A., et al. (2022). Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE). BMJ Open, 12(5), e053417. https://doi.org/10.1136/bmjopen-2021-053417

Labhardt, N. D., Fernández, L. G., Katende, B., Muhairwe, J., Bresser, M., Amstutz, A., Glass, T. R., Ruhwald, M., Sacks, J. A., Escadafal, C., Mareka, M., Mookho, M. S., de Vos, M., & Reither, K. (2022, January 1). Head-to-head comparison of nasal and nasopharyngeal sampling using SARS-CoV-2 rapid antigen testing in Lesotho [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2021.12.29.21268505

Kopo, Mathebe, Lejone, Thabo Ishmael, Tschumi, Nadine, Glass, Tracy Renée, Kao, Mpho, Brown, Jennifer Anne, Seiler, Olivia, Muhairwe, Josephine, Moletsane, Ntoli, Labhardt, Niklaus Daniel, & Amstutz, Alain. (2022). Effectiveness of a Peer Educator-Coordinated Preference-Based Differentiated Delivery Model on Viral Suppression Among Young People Living with HIV in Lesotho: The PEBRA Cluster Randomized Trial [Journal-article]. In SSRN Electronic Journal. RELX Group (Netherlands). https://doi.org/10.2139/ssrn.4019324

Muhairwe, J. A., Brown, J. A., Motaboli, L., Nsakala, B. L., Lerotholi, M., Amstutz, A., Klimkait, T., Glass, T. R., & Labhardt, N. D. (2022). The suboptimal pediatric HIV viral load cascade: multidistrict cohort study among children taking antiretroviral therapy in Lesotho, Southern Africa. Pediatric Infectious Disease Journal, 41(3), e75–e80. https://doi.org/10.1097/inf.0000000000003415

Scherrer, R., Tschumi, N., Lejone, T. I., Kopo, M., Motaboli, L., Mothobi, B., Amstutz, A., Deml, M. J., Lerotholi, M., & Labhardt, N. D. (2022). eHealth supported multi-months dispensing of antiretroviral therapy: a mixed-methods preference assessment in rural Lesotho. Pilot Feasibility Stud, 8(1), 61. https://doi.org/10.1186/s40814-022-01019-x

Speich, Benjamin, Gryaznov, Dmitry, Busse, Jason W., Gloy, Viktoria L., Lohner, Szimonetta, Klatte, Katharina, Taji Heravi, Ala, Ghosh, Nilabh, Lee, Hopin, Mansouri, Anita, Marian, Ioana R., Saccilotto, Ramon, Nury, Edris, Kasenda, Benjamin, Ojeda–Ruiz, Elena, Schandelmaier, Stefan, Tomonaga, Yuki, Amstutz, Alain, Pauli–Magnus, Christiane, et al. (2022). Nonregistration, discontinuation, and nonpublication of randomized trials: a repeated metaresearch analysis. PLoS Medicine, 19(4). https://doi.org/10.1371/journal.pmed.1003980

Tschumi, N., Lerotholi, M., Kopo, M., Kao, M., Lukau, B., Nsakala, B., Chejane, N., Motaboli, L., Lee, T., Barnabas, R., Shapiro, A. E., van Heerden, A., Lejone, T. I., Amstutz, A., Brown, J. A., Heitner, J., Belus, J. M., Chammartin, F., & Labhardt, N. D. (2022). Assessment of a viral load result-triggered automated differentiated service delivery model for people taking ART in Lesotho (the VITAL study): study protocol of a cluster-randomized trial. Plos One, 17(5), e0268100. https://doi.org/10.1371/journal.pone.0268100

Gonzalez Fernandez L., Firima E., Huber J., Raeber F., Amstutz A., Gupta R., Mokhohlane J., Belus J.M., & Labhardt N.D. (2021). Community-based care models for arterial hypertension management in non-pregnant adults in sub-Saharan Africa: A scoping review protocol. F1000Research, 10. https://doi.org/10.12688/f1000research.51929.1

Firima, E., Gonzalez, L., Huber, J., Belus, J. M., Raeber, F., Gupta, R., Mokhohlane, J., Mphunyane, M., Amstutz, A., & Labhardt, N. D. (2021). Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: a scoping review protocol [Journal-article]. F1000Research, 10, 535. https://doi.org/10.12688/f1000research.52114.1

Amstutz, A., Lejone, T. I., Khesa, L., Kopo, M., Kao, M., Muhairwe, J., Bresser, M., Räber, F., Klimkait, T., Battegay, M., Glass, T. R., & Labhardt, N. D. (2021). Offering ART refill through community health workers versus clinic-based follow-up after home-based same-day ART initiation in rural Lesotho: the VIBRA cluster-randomized clinical trial. PLoS Medicine, 18(10), e1003839. https://doi.org/10.1371/journal.pmed.1003839

Amstutz, A., Matsela, L., Lejone, T. I., Kopo, M., Glass, T. R., & Labhardt, N. D. (2021). Reaching absent and refusing individuals during home-based HIV testing through self-testing-at what cost? Front Med, 8, 653677. https://doi.org/10.3389/fmed.2021.653677

Brown, J. A., Amstutz, A., Nsakala, B. L., Seeburg, U., Vanobberghen, F., Muhairwe, J., Klimkait, T., Daniel Labhardt, N., & Daniel Labhardt, N. (2021). Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in resource-limited settings: a pre-planned analysis from the SESOTHO trial. Journal of Antimicrobial Chemotherapy, 76(5), 1294–1298. https://doi.org/10.1093/jac/dkab025

Lohner, Szimonetta, Gryaznov, Dmitry, von Niederhäusern, Belinda, Speich, Benjamin, Kasenda, Benjamin, Ojeda-Ruiz, Elena, Schandelmaier, Stefan, Mertz, Dominik, Odutayo, Ayodele, Tomonaga, Yuki, Amstutz, Alain, Pauli-Magnus, Christiane, Gloy, Viktoria, Bischoff, Karin, Wollmann, Katharina, Rehner, Laura, Meerpohl, Joerg J., Nordmann, Alain, Klatte, Katharina, et al. (2021). Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: A repeated cross-sectional study. Journal of Clinical Epidemiology, 139, 340–349. https://doi.org/10.1016/j.jclinepi.2021.05.011

Mapesi, H., Gupta, R., Wilson, H. I., Lukau, B., Amstutz, A., Lyimo, A., Muhairwe, J., Senkoro, E., Byakuzana, T., Mphunyane, M., Bresser, M., Glass, T. R., Lambiris, M., Fink, G., Gingo, W., Battegay, M., Paris, D. H., Rohacek, M., Vanobberghen, F., et al. (2021). The coArtHA trial-identifying the most effective treatment strategies to control arterial hypertension in sub-Saharan Africa: study protocol for a randomized controlled trial. Trials, 22(1), 77. https://doi.org/10.1186/s13063-021-05023-z

Amstutz, Alain, Kopo, Mathebe, Lejone, Thabo I., Khesa, Lefu, Kao, Mpho, Muhairwe, Josephine, Glass, Tracy R., & Labhardt, Niklaus D. (2020). “If it is left, it becomes easy for me to get tested”: use of oral self-tests and community health workers to maximize the potential of home-based HIV testing among adolescents in Lesoth. Journal of the International AIDS Society, 23(Suppl 5), e25563. https://doi.org/10.1002/jia2.25563

Amstutz, Alain, Lejone, Thabo Ishmael, Khesa, Lefu, Muhairwe, Josephine, Bresser, Moniek, Vanobberghen, Fiona, Kopo, Mathebe, Kao, Mpho, Nsakala, Bienvenu Lengo, Tlali, Katleho, Klimkait, Thomas, Battegay, Manuel, Labhardt, Niklaus Daniel, & Glass, Tracy Renée. (2020). Home-based oral self-testing for absent and declining individuals during a door-to-door HIV testing campaign in rural Lesotho (HOSENG): a cluster-randomised trial. The Lancet. HIV, 7(11), e752–e761. https://doi.org/10.1016/s2352-3018(20)30233-2

Amstutz, Alain, Nsakala, Bienvenu L., Cheleboi, Molisana, Lejone, Thabo I., Hobbins, Michael A., Battegay, Manuel, Klimkait, Thomas, & Labhardt, Niklaus D. (2020). Low rates of active hepatitis B and C infections among adults and children living with HIV and taking antiretroviral therapy: a multicenter screening study in Lesotho. Journal of Medical Virology, 92(12), 3857–3861. https://doi.org/10.1002/jmv.25970

Amstutz, Alain, Nsakala, Bienvenu Lengo, Vanobberghen, Fiona, Muhairwe, Josephine, Glass, Tracy Renée, Namane, Tilo, Mpholo, Tlali, Battegay, Manuel, Klimkait, Thomas, & Labhardt, Niklaus Daniel. (2020). Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho. PLoS medicine, 17(9), e1003325. https://doi.org/10.1371/journal.pmed.1003325

Brown, Jennifer Anne, Ringera, Isaac, Luoga, Ezekiel, Cheleboi, Molisana, Kimera, Namvua, Muhairwe, Josephine, Kayembe, Buntshi Paulin, Molapo Hlasoa, Mosa, Kabundi, Lorraine, Yav, Ching Wey David, Mothobi, Buoang, Thahane, Lineo, Amstutz, Alain, Bachmann, Nadine, Mollel, Getrud Joseph, Bresser, Moniek, Glass, Tracy Renée, Paris, Daniel Henry, Klimkait, Thomas, et al. (2020). Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania. BMC Infectious Diseases, 20(1), 773. https://doi.org/10.1186/s12879-020-05491-9

Gryaznov, D., Odutayo, A., von Niederhausern, B., Speich, B., Kasenda, B., Ojeda-Ruiz, E., Blumle, A., Schandelmaier, S., Mertz, D., Tomonaga, Y., Amstutz, A., Pauli-Magnus, C., Gloy, V., Bischoff, K., Wollmann, K., Rehner, L., Lohner, S., Meerpohl, J. J., Nordmann, A., et al. (2020). Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects. Trials, 21(1), 896. https://doi.org/10.1186/s13063-020-04808-y

Lejone, Thabo Ishmael, Kopo, Mathebe, Bachmann, Nadine, Brown, Jennifer Anne, Glass, Tracy Renée, Muhairwe, Josephine, Matsela, Tebatso, Scherrer, Ramona, Chere, Lebohang, Namane, Tilo, Labhardt, Niklaus Daniel, & Amstutz, Alain. (2020). PEBRA trial - effect of a peer-educator coordinated preference-based ART service delivery model on viral suppression among adolescents and young adults living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho. BMC Public Health, 20(1), 425. https://doi.org/10.1186/s12889-020-08535-6

Amstutz, Alain, Brown, Jennifer Anne, Ringera, Isaac, Muhairwe, Josephine, Lejone, Thabo Ishmael, Klimkait, Thomas, Glass, Tracy Renée, & Labhardt, Niklaus Daniel. (2019). Engagement in care, viral suppression, drug resistance and reasons for non-engagement after home-based same-day ART initiation in Lesotho: a two-year follow-up of the CASCADE trial. Clinical Infectious Diseases, 71(10), 2608–2614. https://doi.org/10.1093/cid/ciz1126

Amstutz, Alain, Lejone, Thabo Ishmael, Khesa, Lefu, Muhairwe, Josephine, Nsakala, Bienvenu Lengo, Tlali, Katleho, Bresser, Moniek, Tediosi, Fabrizio, Kopo, Mathebe, Kao, Mpho, Klimkait, Thomas, Battegay, Manuel, Glass, Tracy Renée, & Labhardt, Niklaus Daniel. (2019). VIBRA trial - Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV : protocol of a cluster-randomized clinical trial in rural Lesotho. Trials, 20(1), 522. https://doi.org/10.1186/s13063-019-3510-5

Amstutz, Alain, Lejone, Thabo Ishmael, Khesa, Lefu, Muhairwe, Josephine, Nsakala, Bienvenu Lengo, Tlali, Katleho, Bresser, Moniek, Vanobberghen, Fiona, Kopo, Mathebe, Kao, Mpho, Klimkait, Thomas, Battegay, Manuel, Labhardt, Niklaus Daniel, & Glass, Tracy Renée. (2019). The HOSENG trial - effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage : protocol of a cluster-randomized clinical trial in rural Lesotho. Trials, 20(1), 496. https://doi.org/10.1186/s13063-019-3469-2

Glass, Tracy Renee, Motaboli, Lipontso, Nsakala, Bienvenu, Lerotholi, Malebanye, Vanobberghen, Fiona, Amstutz, Alain, Lejone, Thabo Ishmael, Muhairwe, Josephine, Klimkait, Thomas, & Labhardt, Niklaus Daniel. (2019). The viral load monitoring cascade in a resource-limited setting : a prospective multicentre cohort study after introduction of routine viral load monitoring in rural Lesotho. PLoS ONE, 14(8), e0220337. https://doi.org/10.1371/journal.pone.0220337

Labhardt, Niklaus Daniel, Ringera, Isaac, Lejone, Thabo Ishmael, Amstutz, Alain, Klimkait, Thomas, Muhairwe, Josephine, & Glass, Tracy Renee. (2019). Effect and cost of two successive home visits to increase HIV testing coverage: a prospective study in Lesotho, Southern Africa. BMC Public Health, 19(1), 1441. https://doi.org/10.1186/s12889-019-7784-z

Speich, Benjamin, Schur, Nadine, Gryaznov, Dmitry, von Niederhäusern, Belinda, Hemkens, Lars G., Schandelmaier, Stefan, Amstutz, Alain, Kasenda, Benjamin, Pauli-Magnus, Christiane, Ojeda-Ruiz, Elena, Tomonaga, Yuki, McCord, Kimberly, Nordmann, Alain, von Elm, Erik, Briel, Matthias, Schwenkglenks, Matthias, & a collaboration of the Marta Aspire Study Groups,. (2019). Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss human research legislation. PLoS ONE, 14(1), e0210669. https://doi.org/10.1371/journal.pone.0210669

Amstutz A, Schandelmaier S, Frei R, Surina J, Agarwal A, Alturki R, von Niederhäusern B, von Elm E, Briel M, & On Behalf Of The MAking Randomized Trials Affordable Marta Group. (2018). Funding characteristics of randomised clinical trials supported by the Swiss National Science Foundation: A retrospective cohort study. Swiss Medical Weekly, 148(3-4), w14587. https://doi.org/10.4414/smw.2018.14587

Amstutz, Alain, Nsakala, Bienvenu Lengo, Vanobberghen, Fiona, Muhairwe, Josephine, Glass, Tracy Renée, Achieng, Beatrice, Sepeka, Mamorena, Tlali, Katleho, Sao, Lebohang, Thin, Kyaw, Klimkait, Thomas, Battegay, Manuel, & Labhardt, Niklaus Daniel. (2018). SESOTHO trial (“Switch Either near Suppression Or THOusand”) - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa. BMC infectious diseases, 18(1), 76. https://doi.org/10.1186/s12879-018-2979-y

Labhardt, N. D., Ringera, I., Lejone, T. I., Klimkait, T., Muhairwe, J., Amstutz, A., & Glass, T. R. (2018). Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in Lesotho : the CASCADE randomized clinical trial. JAMA : The Journal of the American Medical Association, 319(11), 1103–1112. https://doi.org/10.1001/jama.2018.1818

Amstutz A, Schandelmaier S, Frei R, Surina J, Agarwal A, Olu KK, Alturki R, Von Niederhäusern B, Von Elm E, & Briel M. (2017). Discontinuation and non-publication of randomised clinical trials supported by the main public funding body in Switzerland: A retrospective cohort study. BMJ Open, 7(7), e016216. https://doi.org/10.1136/bmjopen-2017-016216