Dr. rer. nat. Christoph Schultheiss

Paschold, L., Schultheiss, C., Schmidt-Barbo, P., Klinghammer, K., Hahn, D., Tometten, M., Schafhausen, P., Blaurock, M., Brandt, A., Westgaard, I., Kowoll, S., Stein, A., Hinke, A., & Binder, M. (2024). Inflammatory signature and restriction of adaptive immunity are associated with unfavorable outcomes on immune checkpoint blockade in patients with advanced head and neck squamous cell carcinoma [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.11.29.24317276

Tintelnot, J., Paschold, L., Goekkurt, E., Schultheiss, C., Matschl, U., Santos Cruz, M., Bauer, M., Wickenhauser, C., Thuss-Patience, P., Lorenzen, S., Ettrich, T. J., Riera-Knorrenschild, J., Jacobasch, L., Kretzschmar, A., Kubicka, S., Al-Batran, S.-E., Reinacher-Schick, A., Pink, D., Bokemeyer, C., et al. (2024). Inflammatory stress determines the need for chemotherapy in patients with HER2-positive esophagogastric adenocarcinoma receiving targeted and immunotherapy [Journal-article]. Cancer Immunology Research. https://doi.org/10.1158/2326-6066.cir-24-0561

Willscher, E., Schultheiß, C., Paschold, L., Lea Schümann, F., Schmidt-Barbo, P., Thiele, B., Bauer, M., Wickenhauser, C., Weber, T., & Binder, M. (2024). T-cell receptor architecture and clonal tiding provide insight into the transformation trajectory of peripheral T-cell lymphomas [Journal-article]. Haematologica. https://doi.org/10.3324/haematol.2024.285395

Schultheiß, C., Paschold, L., Mohebiany, A. N., Escher, M., Kattimani, Y. M., Müller, M., Schmidt-Barbo, P., Mensa-Vilaró, A., Aróstegui, J. I., Boursier, G., de Moreuil, C., Hautala, T., Willscher, E., Jonas, H., Chinchuluun, N., Grosser, B., Märkl, B., Klapper, W., Oommen, P. T., et al. (2024). A20 haploinsufficiency disturbs immune homeostasis and drives the transformation of lymphocytes with permissive antigen receptors [Journal-article]. Science Advances, 10(34). https://doi.org/10.1126/sciadv.adl3975

Schultheiß, C., Willscher, E., Paschold, L., Ackermann, C., Escher, M., Scholz, R., Knapp, M., Lützkendorf, J., Müller, L. P., Schulze zur Wiesch, J., & Binder, M. (2024). B cells expressing mutated IGHV1-69–encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection [Journal-article]. Hepatology Communications, 8(8). https://doi.org/10.1097/hc9.0000000000000503

Schmidt-Barbo, P., Kalweit, G., Naouar, M., Paschold, L., Willscher, E., Schultheiß, C., Märkl, B., Dirnhofer, S., Tzankov, A., Binder, M., & Kalweit, M. (2024). Detection of disease-specific signatures in B cell repertoires of lymphomas using machine learning [Journal-article]. PLOS Computational Biology, 20(7), e1011570. https://doi.org/10.1371/journal.pcbi.1011570

Thiele, B., Stein, A., Schultheiß, C., Paschold, L., Jonas, H., Goekkurt, E., Rüssel, J., Schuch, G., Wierecky, J., Sinn, M., Tintelnot, J., Petersen, C., Rothkamm, K., Vettorazzi, E., & Binder, M. (2024). Trifluridine/tipiracil based chemoradiation in locally advanced rectal cancer - The phase I/II TARC trial [Journal-article]. Clinical Colorectal Cancer. https://doi.org/10.1016/j.clcc.2024.06.003

Cardon, A., Guinebretière, T., Dong, C., Gil, L., Ado, S., Gavlovsky, P.-j., Braud, M., Danger, R., Schultheiß, C., Doméné, A., Paul-Gilloteaux, P., Chevalier, C., Bernier, L., Judor, J.-P., Fourgeux, C., Imbert, A., Khaldi, M., Bardou-Jacquet, E., Elkrief, L., et al. (2024). The immune profile of circulating autoreactive CD4 T cells is imprinted through tissue activation during autoimmune liver diseases [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.03.26.586770

Thuss-Patience, Peter, Högner, Anica, Goekkurt, Eray, Stahl, Michael, Kretzschmar, Albrecht, Götze, Thorsten, Stocker, Gertraud, Reichardt, Peter, Kullmann, Frank, Pink, Daniel, Bartels, Prisca, Jarosch, Armin, Hinke, Axel, Schultheiß, Christoph, Paschold, Lisa, Stein, Alexander, & Binder, Mascha. (2024). Ramucirumab, Avelumab, and Paclitaxel as Second-Line Treatment in Esophagogastric Adenocarcinoma [Journal-article]. JAMA Network Open, 7(1), e2352830. https://doi.org/10.1001/jamanetworkopen.2023.52830

Brandt, Anna, Schultheiss, Christoph, Klinghammer, Konrad, Schafhausen, Philippe, Busch, Chia-Jung, Blaurock, Markus, Hinke, Axel, Tometten, Mareike, Dietz, Andreas, Müller-Richter, Urs, Hahn, Dennis, Alt, Jürgen, Stein, Alexander, & Binder, Mascha. (2024). Tolerability and efficacy of the cancer vaccine UV1 in patients with recurrent or metastatic PD-L1 positive head and neck squamous cell carcinoma planned for first-line treatment with pembrolizumab – the randomized phase 2 FOCUS trial. Frontiers in Oncology, 14. https://doi.org/10.3389/fonc.2024.1283266

Fischer, Claudia, Willscher, Edith, Paschold, Lisa, Gottschick, Cornelia, Klee, Bianca, Diexer, Sophie, Bosurgi, Lidia, Dutzmann, Jochen, Sedding, Daniel, Frese, Thomas, Girndt, Matthias, Hoell, Jessica I., Gekle, Michael, Addo, Marylyn M., Schulze zur Wiesch, Julian, Mikolajczyk, Rafael, Binder, Mascha, & Schultheiß, Christoph. (2024). SARS-CoV-2 vaccination may mitigate dysregulation of IL-1/IL-18 and gastrointestinal symptoms of the post-COVID-19 condition [Journal-article]. npj Vaccines, 9(1). https://doi.org/10.1038/s41541-024-00815-1

Märkl, Florian, Schultheiß, Christoph, Ali, Murtaza, Chen, Shih-Shih, Zintchenko, Marina, Egli, Lukas, Mietz, Juliane, Chijioke, Obinna, Paschold, Lisa, Spajic, Sebastijan, Holtermann, Anne, Dörr, Janina, Stock, Sophia, Zingg, Andreas, Läubli, Heinz, Piseddu, Ignazio, Anz, David, Minden, Marcus Dühren-von, Zhang, Tianjiao, et al. (2024). Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature Communications, 15. https://doi.org/10.1038/s41467-024-45378-w

Mohme, Malte, Schultheiß, Christoph, Piffko, Andras, Fitzek, Antonia, Paschold, Lisa, Thiele, Benjamin, Püschel, Klaus, Glatzel, Markus, Westphal, Manfred, Lamszus, Katrin, Matschke, Jakob, & Binder, Mascha. (2024). SARS-CoV-2-associated T-cell infiltration in the central nervous system [Journal-article]. Clinical and Translational Immunology, 13(2). https://doi.org/10.1002/cti2.1487

Padoan, Benedetta, Casar, Christian, Krause, Jenny, Schultheiss, Christoph, Baumdick, Martin E., Niehrs, Annika, Zecher, Britta F., Pujantell, Maria, Yuki, Yuko, Martin, Maureen, Remmerswaal, Ester B.M., Dekker, Tamara, van der Bom-Baylon, Nelly D., Noble, Janelle A., Carrington, Mary, Bemelman, Frederike J., van Lier, Rene A.W., Binder, Mascha, Gagliani, Nicola, et al. (2024). NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells. Cell Reports, 43. https://doi.org/10.1016/j.celrep.2024.114089

Schmidt-Barbo, P., Kalweit, G., Naouar, M., Paschold, L., Willscher, E., Schultheiß, C., Märkl, B., Dirnhofer, S., Tzankov, A., Binder, M., & Kalweit, M. (2023, October 10). Detection of disease-specific signatures in B cell repertoires of lymphomas using machine learning [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2023.10.05.561150

Märkl, F., Schultheiß, C., Ali, M., Chen, S.-S., Egli, L., Mietz, J., Chijioke, O., Paschold, L., Spajic, S., Holtermann, A., Dörr, J., Stock, S., Piseddu, I., Anz, D., Minden, M. D.-v., Zhang, T., Nerreter, T., Hudecek, M., Chiorazzi, N., et al. (2023, October 2). Mutation-specific CAR T cells as precision therapy for IGLV3-21^R110expressing high-risk chronic lymphocytic leukemia [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2023.09.29.560075

Schultheiß, C., Steinmann, S., Willscher, E., Paschold, L., Lohse, A. W., & Binder, M. (2023). Immune signatures in variant syndromes of primary biliary cholangitis and autoimmune hepatitis [Journal-article]. Hepatology Communications, 7(5). https://doi.org/10.1097/HC9.0000000000000123

Tintelnot, J., Baum, N., Schultheiß, C., Braig, F., Trentmann, M., Finter, J., Fumey, W., Bannas, P., Fehse, B., Riecken, K., Schuetze, K., Bokemeyer, C., Rösner, T., Valerius, T., Peipp, M., Koch-Nolte, F., & Binder, M. (2023, April 3). Data from Nanobody Targeting of Epidermal Growth Factor Receptor (EGFR) Ectodomain Variants Overcomes Resistance to Therapeutic EGFR Antibodies [Posted-content]. American Association for Cancer Research (AACR). https://doi.org/10.1158/1535-7163.c.6538192.v1

Schultheiß, C., Willscher, E., Paschold, L., Ackermann, C., Escher, M., Scholz, R., Knapp, M., Lützkendorf, J., Müller, L., Wiesch, J. S. z., & Binder, M. (2023, March 29). IGHV1-69 BCRs with virus-neutralizing mutations show lymphoma-like transcriptomes in patients with chronic HCV infection [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-2719495/v1

Brandt, Anna, Thiele, Benjamin, Schultheiß, Christoph, Daetwyler, Eveline, & Binder, Mascha. (2023). Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma. Cancers, 15. https://doi.org/10.3390/cancers15072051

Lübbering, D., Preti, M., Schlott, L., Schultheiß, C., Weidemann, S., Lohse, A. W., Binder, M., Carambia, A., & Herkel, J. (2023). Autoantigen-selected B cells are bystanders in spontaneous T cell-driven experimental autoimmune hepatitis. Immunology, 170, 214–229. https://doi.org/10.1111/imm.13665

Marcinkevics, Ricards, Silva, Pamuditha N., Hankele, Anna-Katharina, Dörnte, Charlyn, Kadelka, Sarah, Csik, Katharina, Godbersen, Svenja, Goga, Algera, Hasenöhrl, Lynn, Hirschi, Pascale, Kabakci, Hasan, LaPierre, Mary P., Mayrhofer, Johanna, Title, Alexandra C., Shu, Xuan, Baiioud, Nouell, Bernal, Sandra, Dassisti, Laura, Saenz-de-Juano, Mara D., et al. (2023). Machine learning analysis of humoral and cellular responses to SARS-CoV-2 infection in young adults [Journal-article]. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1158905

Paschold, Lisa, Gottschick, Cornelia, Langer, Susan, Klee, Bianca, Diexer, Sophie, Aksentijevich, Ivona, Schultheiß, Christoph, Purschke, Oliver, Riese, Peggy, Trittel, Stephanie, Haase, Roland, Dressler, Frank, Eberl, Wolfgang, Hübner, Johannes, Strowig, Till, Guzman, Carlos A., Mikolajczyk, Rafael, & Binder, Mascha. (2023). T cell repertoire breadth is associated with the number of acute respiratory infections in the LoewenKIDS birth cohort. Scientific Reports, 13. https://doi.org/10.1038/s41598-023-36144-x

Paschold, Lisa, Stein, Alexander, Thiele, Benjamin, Tintelnot, Joseph, Henkes, Svenja-Sibylla, Coith, Cornelia, Schultheiß, Christoph, Pantel, Klaus, Riethdorf, Sabine, & Binder, Mascha. (2023). First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial. Journal for ImmunoTherapy of Cancer, 11. https://doi.org/10.1136/jitc-2023-006678

Schultheiß, C., Willscher, E., Paschold, L., Gottschick, C., Klee, B., Bosurgi, L., Dutzmann, J., Sedding, D., Frese, T., Girndt, M., Höll, J. I., Gekle, M., Mikolajczyk, R., & Binder, M. (2023). Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post-acute sequelae of COVID-19. Journal of Medical Virology, 95. https://doi.org/10.1002/jmv.28364

Schultheiß, C., Willscher, E., Paschold, L., Gottschick, C., Klee, B., Bosurgi, L., Dutzmann, J., Sedding, D., Frese, T., Girndt, M., Höll, J. I., Gekle, M., Mikolajczyk, R., & Binder, M. (2022, September 19). Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post-acute sequelae of COVID-19 [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.09.18.22280022

Claaß, L. V., Schultheiß, C., Scholz, R., Paschold, L., Simnica, D., Heinemann, V., Stintzing, S., & Binder, M. (2022). PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.941666

Paschold, L., Klee, B., Gottschick, C., Willscher, E., Diexer, S., Schultheiß, C., Simnica, D., Sedding, D., Girndt, M., Gekle, M., Mikolajczyk, R., & Binder, M. (2022). Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.876306

Paschold, L., Simnica, D., Brito, R. B., Zhang, T., Schultheiß, C., Dierks, C., & Binder, M. (2022). Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21^R110 chronic lymphocytic leukemia. Blood Cancer Journal, 12. https://doi.org/10.1038/s41408-022-00650-4

Schultheiß, C., & Binder, M. (2022). Overcoming unintended immunogenicity in immunocompetent mouse models of metastasis: the case of GFP. Signal Transduction and Targeted Therapy, 7. https://doi.org/10.1038/s41392-022-00929-9

Schultheiß, C., Steinmann, S., Lohse, A. W., & Binder, M. (2022). B cells in autoimmune hepatitis: bystanders or central players? Seminars in Immunopathology, 44, 411–427. https://doi.org/10.1007/s00281-022-00937-5

Schultheiß, C., Willscher, E., Paschold, L., Gottschick, C., Klee, B., Henkes, S.-S., Bosurgi, L., Dutzmann, J., Sedding, D., Frese, T., Girndt, M., Höll, J. I., Gekle, M., Mikolajczyk, R., & Binder, M. (2022). The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19. Cell Reports Medicine, 3. https://doi.org/10.1016/j.xcrm.2022.100663

Stein, A., Paschold, L., Tintelnot, J., Goekkurt, E., Henkes, S.-S., Simnica, D., Schultheiss, C., Willscher, E., Bauer, M., Wickenhauser, C., Thuss-Patience, P., Lorenzen, S., Ettrich, T., Riera-Knorrenschild, J., Jacobasch, L., Kretzschmar, A., Kubicka, S., Al-Batran, S.-E., Reinacher-Schick, A., et al. (2022). Efficacy of Ipilimumab vs FOLFOX in Combination with Nivolumab and Trastuzumab in Patients with Previously Untreated ERBB2-Positive Esophagogastric Adenocarcinoma: The AIO INTEGA Randomized Clinical Trial. 8, 1150–1158. https://doi.org/10.1001/jamaoncol.2022.2228

Tintelnot, J., Ristow, I., Sauer, M., Simnica, D., Schultheiß, C., Scholz, R., Goekkurt, E., von Wenserski, L., Willscher, E., Paschold, L., Lorenzen, S., Riera-Knorrenschild, J., Depenbusch, R., Ettrich, T. J., Dörfel, S., Al-Batran, S.-E., Karthaus, M., Pelzer, U., Hinke, A., et al. (2022). Translational analysis and final efficacy of the AVETUX trial – Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.993611

Schultheiß, C., Willscher, E., Paschold, L., Gottschick, C., Klee, B., Henkes, S.-S., Bosurgi, L., Dutzmann, J., Sedding, D., Frese, T., Girndt, M., Höll, J. I., Gekle, M., Mikolajczyk, R., & Binder, M. (2021, November 16). From online data collection to identification of disease mechanisms: The IL-1ß, IL-6 and TNF-α cytokine triad is associated with post-acute sequelae of COVID-19 in a digital research cohort [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2021.11.16.21266391

Chernyakov, D., Groß, A., Fischer, A., Bornkessel, N., Schultheiss, C., Gerloff, D., & Edemir, B. (2021). Loss of RANBP3L leads to transformation of renal epithelial cells towards a renal clear cell carcinoma like phenotype. Journal of Experimental and Clinical Cancer Research, 40. https://doi.org/10.1186/s13046-021-01982-y

Grehl, C., Schultheiß, C., Hoffmann, K., Binder, M., Altmann, T., Grosse, I., & Kuhlmann, M. (2021). Detection of sars‐cov‐2 derived small rnas and changes in circulating small rnas associated with covid‐19. Viruses, 13. https://doi.org/10.3390/v13081593

Grehl, C., Schultheiß, C., Hoffmann, K., Binder, M., Altmann, T., Grosse, I., & Kuhlmann, M. (2021). Severe Cases of COVID-19 Are Associated with Changes in Circulating Small RNA [Journal-article]. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.3844793

Paschold, L., Simnica, D., Willscher, E., Vehreschild, M. J. G. T., Dutzmann, J., Sedding, D. G., Schultheiß, C., & Binder, M. (2021). SARS-CoV-2-specific antibody rearrangements in prepandemic immune repertoires of risk cohorts and patients with COVID-19. Journal of Clinical Investigation, 131. https://doi.org/10.1172/jci142966

Porritt, R. A., Paschold, L., Rivas, M. N., Cheng, M. H., Yonker, L. M., Chandnani, H., Lopez, M., Simnica, D., Schultheiß, C., Santiskulvong, C., Van Eyk, J., McCormick, J. K., Fasano, A., Bahar, I., Binder, M., & Arditi, M. (2021). HLA class I–associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children. Journal of Clinical Investigation, 131. https://doi.org/10.1172/jci146614

Schultheiß, C., Paschold, L., Willscher, E., Simnica, D., Wöstemeier, A., Muscate, F., Wass, M., Eisenmann, S., Dutzmann, J., Keyßer, G., Gagliani, N., & Binder, M. (2021). Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19. iScience, 24. https://doi.org/10.1016/j.isci.2021.103325

Schultheiß, C., Simnica, D., Willscher, E., Oberle, A., Fanchi, L., Bonzanni, N., Wildner, N. H., Schulze Zur Wiesch, J., Weiler-Normann, C., Lohse, A. W., & Binder, M. (2021). Next-Generation Immunosequencing Reveals Pathological T-Cell Architecture in Autoimmune Hepatitis. Hepatology, 73, 1436–1448. https://doi.org/10.1002/hep.31473

Simnica, D., Schultheiß, C., Mohme, M., Paschold, L., Willscher, E., Fitzek, A., Püschel, K., Matschke, J., Ciesek, S., Sedding, D. G., Zhao, Y., Gagliani, N., Maringer, Y., Walz, J. S., Heide, J., Schulze-zur-Wiesch, J., & Binder, M. (2021). Landscape of T-cell repertoires with public COVID-19-associated T-cell receptors in pre-pandemic risk cohorts. Clinical and Translational Immunology, 10. https://doi.org/10.1002/cti2.1340

Stein, A., Simnica, D., Schultheiß, C., Scholz, R., Tintelnot, J., Gökkurt, E., Von Wenserski, L., Willscher, E., Paschold, L., Sauer, M., Lorenzen, S., Riera-Knorrenschild, J., Depenbusch, R., Ettrich, T. J., Dörfel, S., Al-Batran, S.-E., Karthaus, M., Pelzer, U., Waberer, L., et al. (2021). PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer. Journal for ImmunoTherapy of Cancer, 9. https://doi.org/10.1136/jitc-2021-002844

von Wenserski, L., Schultheiß, C., Bolz, S., Schliffke, S., Simnica, D., Willscher, E., Gerull, H., Wolters-Eisfeld, G., Riecken, K., Fehse, B., Altfeld, M., Nollau, P., & Binder, M. (2021). SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2. Leukemia, 35, 1073–1086. https://doi.org/10.1038/s41375-020-01025-z

Schultheiß, C., Willscher, E., Paschold, L., Gottschick, C., Klee, B., Glasauer, S., Henkes, S.-S., Bosurgi, L., Dutzmann, J., Sedding, D. G., Frese, T., Girndt, M., Höll, J. I., Gekle, M., Mikolajczyk, R., & Binder, M. (2021). From Online Data Collection to Identification of Disease Mechanisms: The IL-1ß, IL-6 and TNF-α Cytokine Triad Is Associated With Post-Acute Sequelae of COVID-19 in a Digital Research Cohort [Journal-article]. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.3963839

Zhao, Y., Kilian, C., Turner, J.-E., Bosurgi, L., Roedl, K., Bartsch, P., Gnirck, A.-C., Cortesi, F., Schultheiß, C., Hellmig, M., Enk, L. U. B., Hausmann, F., Borchers, A., Wong, M. N., Paust, H.-J., Siracusa, F., Scheibel, N., Herrmann, M., Rosati, E., et al. (2021). Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients. Science Immunology, 6. https://doi.org/10.1126/sciimmunol.abf6692

Porritt, R. A., Paschold, L., Rivas, M. N., Cheng, M. H., Yonker, L. M., Chandnani, H., Lopez, M., Simnica, D., Schultheiß, C., Santiskulvong, C., Van Eyk, J., Fasano, A., Bahar, I., Binder, M., & Arditi, M. (2020, November 9). Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2020.11.09.372169

Schultheiß, C., Paschold, L., Simnica, D., Mohme, M., Willscher, E., von Wenserski, L., Scholz, R., Wieters, I., Dahlke, C., Tolosa, E., Sedding, D. G., Ciesek, S., Addo, M., & Binder, M. (2020). Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease. Immunity, 53, 442–455. https://doi.org/10.1016/j.immuni.2020.06.024

Simnica, D., Paschold, L., Willscher, E., Ciesek, S., Sedding, D. G., Schultheiß, C., & Binder, M. (2020). Landscape of Public T Cell Receptors Associated with Recovery from COVID-19 [Journal-article]. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.3682253

Tintelnot, J., Metz, S., Trentmann, M., Oberle, A., von Wenserski, L., Schultheiß, C., Braig, F., Kriegs, M., Fehse, B., Riecken, K., Bokemeyer, C., Stein, A., & Binder, M. (2020). Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling. Frontiers in Oncology, 9. https://doi.org/10.3389/fonc.2019.01559

Schultheiß, C., Paschold, L., Simnica, D., Mohme, M., Willscher, E., von Wenserski, L., Scholz, R., Wieters, I., Dahlke, C., Tolosa, E., Sedding, D. G., Ciesek, S., Addo, M., & Binder, M. (2020). Living Repository of Millions of T and B Cell Receptor Sequences from Patients with COVID-19 [Journal-article]. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.3624431

Simnica, D., Schliffke, S., Schultheiß, C., Bonzanni, N., Fanchi, L. F., Akyüz, N., Gösch, B., Casar, C., Thiele, B., Schlüter, J., Lohse, A. W., & Binder, M. (2019). High-throughput immunogenetics reveals a lack of physiological T cell clusters in patients with autoimmune cytopenias. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.01897

Tintelnot, Joseph, Baum, Natalie, Schultheiß, Christoph, Braig, Friederike, Trentmann, Marie, Finter, Johannes, Fumey, William, Bannas, Peter, Fehse, Boris, Riecken, Kristoffer, Schuetze, Kerstin, Bokemeyer, Carsten, Rosner, Thies, Valerius, Thomas, Peipp, Matthias, Koch-Nolte, Friedrich, & Binder, Mascha. (2019). Nanobody targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies. Molecular Cancer Therapeutics, 18, 823–833. https://doi.org/10.1158/1535-7163.mct-18-0849

Hacker, B., Schultheiß, C., Döring, M., & Kurzik-Dumke, U. (2018). Molecular partners of hNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, suggest its involvement in distinct cellular processes relevant to congenital disorders of glycosylation, cancer, neurodegeneration and a variety of further pathologies. Human Molecular Genetics, 27, 1858–1878. https://doi.org/10.1093/hmg/ddy087

Hacker, B., Schultheiß, C., & Kurzik-Dumke, U. (2018). Sequential cleavage of the proteins encoded by HNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, results in products acting in distinct cellular compartments. Human Molecular Genetics, 27, 4231–4248. https://doi.org/10.1093/hmg/ddy315