Prof. Dr. med. Ludwig Kappos

Oechtering, Johanna, Schaedelin, Sabine Anna, Stein, Kerstin, Maleska Maceski, Aleksandra, Melie-Garcia, Lester, Benkert, Pascal, Cagol, Alessandro, Leber, Selina, Galbusera, Riccardo, Ruberte, Esther, Hu, Wayne, Qureshi, Ferhan, Orleth, Annette, Demuth, Lilian, Willemse, Eline, Heijnen, Ingmar, Regeniter, Axel, Derfuss, Tobias J., Fischer-Barnicol, Bettina, et al. (2025). Aberrant Complement Activation Is Associated With Structural Brain Damage in Multiple Sclerosis [Journal-article]. Neurology Neuroimmunology & Neuroinflammation, 12(2). https://doi.org/10.1212/nxi.0000000000200361

Pontillo, G., Prados, F., Wink, A. M., Kanber, B., Bisecco, A., Broeders, T. A. A., Brunetti, A., Cagol, A., Calabrese, M., Castellaro, M., Cocozza, S., Colato, E., Collorone, S., Cortese, R., De Stefano, N., Douw, L., Enzinger, C., Filippi, M., Foster, M. A., et al. (2025). More Than the Sum of Its Parts: Disrupted Core Periphery of Multiplex Brain Networks in Multiple Sclerosis. Human Brain Mapping, 46(1). https://doi.org/10.1002/hbm.70107

Oh, J., Capezzuto, L., Kriara, L., Schjodt-Eriksen, J., van Beek, J., Bernasconi, C., Montalban, X., Butzkueven, H., Kappos, L., Giovannoni, G., Bove, R., Julian, L., Baker, M., Gossens, C., & Lindemann, M. (2024). Use of smartphone-based remote assessments of multiple sclerosis in Floodlight Open, a global, prospective, open-access study. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-023-49299-4

Woelfle, Tim, Hirt, Julian, Janiaud, Perrine, Kappos, Ludwig, Ioannidis, John P.A., & Hemkens, Lars G. (2024). Benchmarking Human–AI collaboration for common evidence appraisal tools. Journal of Clinical Epidemiology, 175. https://doi.org/10.1016/j.jclinepi.2024.111533

Geraldes, R., Arrambide, G., Banwell, B., Rovira, À., Cortese, R., Lassmann, H., Messina, S., Rocca, M. A., Waters, P., Chard, D., Gasperini, C., Hacohen, Y., Mariano, R., Paul, F., DeLuca, G. C., Enzinger, C., Kappos, L., Leite, M. I., Sastre-Garriga, J., et al. (2024). The influence of MOGAD on diagnosis of multiple sclerosis using MRI. Nature Reviews Neurology, 20(10), 620–635. https://doi.org/10.1038/s41582-024-01005-2

Sastre-Garriga, J., Vidal-Jordana, A., Toosy, A. T., Enzinger, C., Granziera, C., Frederiksen, J., Ciccarelli, O., Filippi, M., Montalban, X., Tintore, M., Pareto, D., Rovira, À., Rocca, M. A., De Stefano, N., Gasperini, C., Kappos, L., Palace, J., Vrenken, H., Barkhofghi, F., & Yousry, T. A. (2024). Value of Optic Nerve MRI in Multiple Sclerosis Clinical Management: A MAGNIMS Position Paper and Future Perspectives. Neurology, 103(3). https://doi.org/10.1212/WNL.0000000000209677

Ciccarelli, O., Barkhof, F., Calabrese, M., De Stefano, N., Eshaghi, A., Filippi, M., Gasperini, C., Granziera, C., Kappos, L., Rocca, M. A., Rovira, À., Sastre-Garriga, J., Sormani, M. P., Tur, C., & Toosy, A. T. (2024). Using the Progression Independent of Relapse Activity Framework to Unveil the Pathobiological Foundations of Multiple Sclerosis [Journal-article]. Neurology, 103(1). https://doi.org/10.1212/wnl.0000000000209444

Chitnis, T., Banwell, B., Kappos, L., Arnold, D. L., Gücüyener, K., Deiva, K., Saubadu, S., Hu, W., Benamor, M., Le-Halpere, A., Truffinet, P., & Tardieu, M. (2024). Teriflunomide in pediatric patients with relapsing multiple sclerosis: Open-label extension of TERIKIDS. Multiple Sclerosis Journal, 30(7), 833–842. https://doi.org/10.1177/13524585241242050

Wendebourg, Maria Janina, Weigel, Matthias, Weidensteiner, Claudia, Sander, Laura, Kesenheimer, Eva, Naumann, Nicole, Haas, Tanja, Madoerin, Philipp, Braun, Nathalie, Neuwirth, Christoph, Weber, Markus, Jahn, Kathleen, Kappos, Ludwig, Granziera, Cristina, Schweikert, Kathi, Sinnreich, Michael, Bieri, Oliver, & Schlaeger, Regina. (2024). Cervical and thoracic spinal cord gray matter atrophy is associated with disability in patients with amyotrophic lateral sclerosis [Journal-article]. European Journal of Neurology, 31(6). https://doi.org/10.1111/ene.16268

Fox, R. J., Cree, B. A. C., de Sèze, J., Gold, R., Hartung, H.-P., Jeffery, D., Kappos, L., Montalban, X., Weinstock-Guttman, B., Singh, C. M., Altincatal, A., Belviso, N., Avila, R. L., Ho, P.-R., Su, R., Engle, R., Sangurdekar, D., de Moor, C., Fisher, E., et al. (2024). Temporal Relationship Between Serum Neurofilament Light Chain and Radiologic Disease Activity in Patients With Multiple Sclerosis. Neurology, 102(9). https://doi.org/10.1212/wnl.0000000000209357

Woelfle, Tim, Hirt, Julian, Janiaud, Perrine, Kappos, Ludwig, Ioannidis, John P. A., & Hemkens, Lars G. (2024). Benchmarking Human-AI Collaboration for Common Evidence Appraisal Tools [Posted-content]. In medRxiv. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.04.21.24306137

Weigel, M., Dechent, P., Galbusera, R., Bahn, E., Lu, P.-J., Kappos, L., Brück, W., Stadelmann, C., & Granziera, C. (2024). Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.04.18.589707

Lazzarotto, A., Hamzaoui, M., Tonietto, M., Dubessy, A.-L., Khalil, M., Pirpamer, L., Ropele, S., Enzinger, C., Battaglini, M., Stromillo, M. L., De Stefano, N., Filippi, M., Rocca, M. A., Gallo, P., Gasperini, C., Stankoff, B., Bodini, B., Barkhof, F., Sastre-Garriga, J., et al. (2024). Time is myelin: early cortical myelin repair prevents atrophy and clinical progression in multiple sclerosis. Brain, 147(4), 1331–1343. https://doi.org/10.1093/brain/awae024

Janiaud, Perrine, Zecca, Chiara, Salmen, Anke, Benkert, Pascal, Schädelin, Sabine, Orleth, Annette, Demuth, Lilian, Maceski, Aleksandra Maleska, Granziera, Cristina, Oechtering, Johanna, Leppert, David, Derfuss, Tobias, Achtnichts, Lutz, Findling, Oliver, Roth, Patrick, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, et al. (2024). MultiSCRIPT-Cycle 1- A Pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in Multiple Sclerosis: a study protocol for a randomized clinical trial [Posted-content]. In medRxiv. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.03.22.24304720

Cagol, Alessandro, Cortese, Rosa, Barakovic, Muhamed, Schaedelin, Sabine, Ruberte, Esther, Absinta, Martina, Barkhof, Frederik, Calabrese, Massimiliano, Castellaro, Marco, Ciccarelli, Olga, Cocozza, Sirio, De Stefano, Nicola, Enzinger, Christian, Filippi, Massimo, Jurynczyk, Maciej, Maggi, Pietro, Mahmoudi, Nima, Messina, Silvia, Montalban, Xavier, et al. (2024). Diagnostic Performance of Cortical Lesions and the Central Vein Sign in Multiple Sclerosis [Journal-article]. JAMA Neurology, 81(2), 143. https://doi.org/10.1001/jamaneurol.2023.4737

Barakovic, Muhamed, Weigel, Matthias, Cagol, Alessandro, Schaedelin, Sabine, Galbusera, Riccardo, Lu, Po-Jui, Chen, Xinjie, Melie-Garcia, Lester, Ocampo-Pineda, Mario, Bahn, Erik, Stadelmann, Christine, Palombo, Marco, Kappos, Ludwig, Kuhle, Jens, Magon, Stefano, & Granziera, Cristina. (2024). A novel imaging marker of cortical “cellularity” in multiple sclerosis patients [Journal-article]. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-60497-6

Benkert, Pascal, Maleska Maceski, Aleksandra, Schaedelin, Sabine, Oechtering, Johanna, Zadic, Amar, Vilchez Gomez, Juan Francisco, Melie-Garcia, Lester, Cagol, Alessandro, Galbusera, Riccardo, Subramaniam, Suvitha, Lorscheider, Johannes, Galli, Edoardo, Mueller, Jannis, Fischer-Barnicol, Bettina, Achtnichts, Lutz, Findling, Oliver, Lalive, Patrice H., Bridel, Claire, Uginet, Marjolaine, et al. (2024). Serum Glial Fibrillary Acidic Protein and Neurofilament Light Chain Levels Reflect Different Mechanisms of Disease Progression under B-Cell Depleting Treatment in Multiple Sclerosis. Annals of Neurology. https://doi.org/10.1002/ana.27096

Cagol, Alessandro, Benkert, Pascal, Melie-Garcia, Lester, Schaedelin, Sabine A., Leber, Selina, Tsagkas, Charidimos, Barakovic, Muhamed, Galbusera, Riccardo, Lu, Po-Jui, Weigel, Matthias, Ruberte, Esther, Radue, Ernst-Wilhelm, Yaldizli, Özgür, Oechtering, Johanna, Lorscheider, Johannes, D’Souza, Marcus, Fischer-Barnicol, Bettina, Muller, Stefanie, Achtnichts, Lutz, et al. (2024). Association of Spinal Cord Atrophy and Brain Paramagnetic Rim Lesions With Progression Independent of Relapse Activity in People With MS. Neurology, 102. https://doi.org/10.1212/wnl.0000000000207768

Cagol, Alessandro, Ocampo-Pineda, Mario, Lu, Po-Jui, Weigel, Matthias, Barakovic, Muhamed, Melie-Garcia, Lester, Chen, Xinjie, Lutti, Antoine, Calabrese, Pasquale, Kuhle, Jens, Kappos, Ludwig, Sormani, Maria Pia, & Granziera, Cristina. (2024). Advanced Quantitative MRI Unveils Microstructural Thalamic Changes Reflecting Disease Progression in Multiple Sclerosis [Journal-article]. Neurology: Neuroimmunology and NeuroInflammation, 11(6). https://doi.org/10.1212/NXI.0000000000200299

Callegari, Ilaria, Oechtering, Johanna, Schneider, Mika, Perriot, Sylvain, Mathias, Amandine, Voortman, Margarete M., Cagol, Alessandro, Lanner, Ulrike, Diebold, Martin, Holdermann, Sebastian, Kreiner, Victor, Becher, Burkhard, Granziera, Cristina, Junker, Andreas, Pasquier, Renaud Du, Khalil, Michael, Kuhle, Jens, Kappos, Ludwig, Sanderson, Nicholas S.R., & Derfuss, Tobias. (2024). Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5. Brain, 147, 839–848. https://doi.org/10.1093/brain/awad424

Cortese, Rosa, Battaglini, Marco, Prados, Ferran, Gentile, Giordano, Luchetti, Ludovico, Bianchi, Alessia, Haider, Lukas, Jacob, Anu, Palace, Jacqueline, Messina, Silvia, Paul, Friedemann, Marignier, Romain, Durand-Dubief, Françoise, de Medeiros Rimkus, Carolina, Apostolos Pereira, Samira Luisa, Sato, Douglas Kazutoshi, Filippi, Massimo, Rocca, M.A., Cacciaguerra, Laura, et al. (2024). Grey Matter Atrophy and its Relationship with White Matter Lesions in Patients with Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder, and Multiple Sclerosis. Annals of Neurology, 96, 276–288. https://doi.org/10.1002/ana.26951

Derfuss, T., Bermel, R., Lin, C.-J., Hauser, S. L., Kappos, L., Vollmer, T., Comi, G., Giovannoni, G., Hartung, H.-P., Weber, M. S., Wang, J., Jessop, N., Chognot, C., Craveiro, L., & Bar-Or, A. (2024). Long-term analysis of infections and associated risk factors in patients with multiple sclerosis treated with ocrelizumab: pooled analysis of 13 interventional clinical trials [Journal-article]. Therapeutic Advances in Neurological Disorders, 17. https://doi.org/10.1177/17562864241277736

Galbusera, Riccardo, Bahn, Erik, Weigel, Matthias, Cagol, Alessandro, Lu, Po-Jui, Schaedelin, Sabine A., Franz, Jonas, Barakovic, Muhamed, Rahmanzadeh, Reza, Dechent, Peter, Nair, Govind, Brück, Wolfgang, Kuhle, Jens, Kappos, Ludwig, Stadelmann, Christine, & Granziera, Cristina. (2024). Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple Sclerosis. Neurology, 102, e207966. https://doi.org/10.1212/wnl.0000000000207966

Gloor M, Andelova M, Gaetano L, Papadopoulou A, Burguet Villena F, Sprenger T, Radue EW, Kappos L, Bieri O, & Garcia M. (2024). Longitudinal analysis of new multiple sclerosis lesions with magnetization transfer and diffusion tensor imaging. European Society of Radiology. https://doi.org/10.1007/s00330-023-10173-6

Gomes, Ana Beatriz Ayroza Galvão Ribeiro, Kim, Su-Hyun, Pretzsch, Roxanne, Kulsvehagen, Laila, Schaedelin, Sabine, Lerner, Jasmine, Wetzel, Nora Sandrine, Benkert, Pascal, Maceski, Aleksandra Maleska, Hyun, Jae-Won, Lecourt, Anne-Catherine, Lipps, Patrick, Schoeps, Vinicius Andreoli, De Moura Brasil Matos, Aline, Mendes, Natalia Trombini, Apóstolos-Pereira, Samira Luisa, Mehling, Matthias, Derfuss, Tobias, Kappos, Ludwig, et al. (2024). Neurofilament Light Chain as a Discriminator of Disease Activity Status in MOG Antibody-Associated Disease [Journal-article]. Neurology: Neuroimmunology and NeuroInflammation, 12(1). https://doi.org/10.1212/NXI.0000000000200347

Greselin, Martina, Lu, Po-Jui, Melie-Garcia, Lester, Ocampo-Pineda, Mario, Galbusera, Riccardo, Cagol, Alessandro, Weigel, Matthias, de Oliveira Siebenborn, Nina, Ruberte, Esther, Benkert, Pascal, Müller, Stefanie, Finkener, Sebastian, Vehoff, Jochen, Disanto, Giulio, Findling, Oliver, Chan, Andrew, Salmen, Anke, Pot, Caroline, Bridel, Claire, et al. (2024). Contrast-Enhancing Lesion Segmentation in Multiple Sclerosis: A Deep Learning Approach Validated in a Multicentric Cohort [Journal-article]. Bioengineering, 11(8), 858. https://doi.org/10.3390/bioengineering11080858

Hirt, Julian, Dembowska, Kinga, Woelfle, Tim, Axfors, Cathrine, Granziera, Cristina, Kuhle, Jens, Kappos, Ludwig, Hemkens, Lars G., & Janiaud, Perrine. (2024). Clinical trial evidence of quality-of-life effects of disease-modifying therapies for multiple sclerosis: a systematic analysis. Journal of Neurology. https://doi.org/10.1007/s00415-024-12366-5

Hirt, Julian, Janiaud, Perrine, Düblin, Pascal, Nicoletti, Giovanni Jacopo, Dembowska, Kinga, Nguyen, Thao Vy Thi, Woelfle, Tim, Axfors, Cathrine, Yaldizli, Özgür, Granziera, Cristina, Kuhle, Jens, Kappos, Ludwig, & Hemkens, Lars G. (2024). Use of pragmatic randomized trials in multiple sclerosis: A systematic overview. Multiple Sclerosis Journal, 30, 463–478. https://doi.org/10.1177/13524585231221938

Janiaud, Perrine, Zecca, Chiara, Salmen, Anke, Benkert, Pascal, Schädelin, Sabine, Orleth, Annette, Demuth, Lilian, Maceski, Aleksandra Maleska, Granziera, Cristina, Oechtering, Johanna, Leppert, David, Derfuss, Tobias, Achtnichts, Lutz, Findling, Oliver, Roth, Patrick, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, et al. (2024). MultiSCRIPT-Cycle 1—a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial. Trials, 25. https://doi.org/10.1186/s13063-024-08454-6

Kappos, L., Edan, G., Freedman, M. S., Hartung, H.-P., Montalbán, X., Barkhof, F., Koelbach, R., MacManus, D. G., & Wicklein, E.-M. (2024). Long-term clinical outcomes in patients with CIS treated with interferon beta-1b: results from the 15-year follow up of the BENEFIT trial. Journal of Neurology. https://doi.org/10.1007/s00415-024-12417-x

Kappos, Ludwig, Traboulsee, Anthony, Li, David K. B., Bar-Or, Amit, Barkhof, Frederik, Montalban, Xavier, Leppert, David, Baldinotti, Anna, Schneble, Hans-Martin, Koendgen, Harold, Sauter, Annette, Wang, Qing, & Hauser, Stephen L. (2024). Ocrelizumab exposure in relapsing–remitting multiple sclerosis: 10-year analysis of the phase 2 randomized clinical trial and its extension. Journal of Neurology, 271, 642–657. https://doi.org/10.1007/s00415-023-11943-4

Khalil, Michael, Teunissen, Charlotte E., Lehmann, Sylvain, Otto, Markus, Piehl, Fredrik, Ziemssen, Tjalf, Bittner, Stefan, Sormani, Maria Pia, Gattringer, Thomas, Abu-Rumeileh, Samir, Thebault, Simon, Abdelhak, Ahmed, Green, Ari, Benkert, Pascal, Kappos, Ludwig, Comabella, Manuel, Tumani, Hayrettin, Freedman, Mark S., Petzold, Axel, et al. (2024). Neurofilaments as biomarkers in neurological disorders — towards clinical application. Nature Reviews Neurology, 20, 269–287. https://doi.org/10.1038/s41582-024-00955-x

Mallucci, Giulia, Zimmer, Andrea, Sfikas, Nikolaos, Cerdá-Fuertes, Nuria, Wunderlin, Simon, Athanasopoulou, Ioanna, Mroczek, Magdalena, Phavanh, Vanny, Sanak, Lisa, Suter, Jolanda, Friedli, Bernadette, Kel, Jakob, Trouillet, Thomas, Simmen, Sarah, Ocampo, Alex, Wei, Wenjia, Kieseier, Bernd, Kamm, Christian P, Kappos, Ludwig, & D’Souza, Marcus. (2024). Neurostatus-SMARTCARE clinical trial: Enabling health care professionals to assess EDSS for decentralized trials in multiple sclerosis. Multiple Sclerosis Journal. https://doi.org/10.1177/13524585241305966

Müller, Jannis, Lu, Po-Jui, Cagol, Alessandro, Ruberte, Esther, Shin, Hyeong-Geol, Ocampo-Pineda, Mario, Chen, Xinjie, Tsagkas, Charidimos, Barakovic, Muhamed, Galbusera, Riccardo, Weigel, Matthias, Schaedelin, Sabine A., Wang, Yi, Nguyen, Thanh D., Spincemaille, Pascal, Kappos, Ludwig, Kuhle, Jens, Lee, Jongho, & Granziera, Cristina. (2024). Quantifying Remyelination Using χ-Separation in White Matter and Cortical Multiple Sclerosis Lesions [Journal-article]. Neurology, 103(6). https://doi.org/10.1212/WNL.0000000000209604

Oechtering, Johanna, Stein, Kerstin, Schaedelin, Sabine A., Maceski, Aleksandra M., Orleth, Annette, Meier, Stephanie, Willemse, Eline, Qureshi, Ferhan, Heijnen, Ingmar, Regeniter, Axel, Derfuss, Tobias, Benkert, Pascal, D’Souza, Marcus, Limberg, Marguerite, Fischer-Barnicol, Bettina, Achtnichts, Lutz, Mueller, Stefanie, Salmen, Anke, Lalive, Patrice H., et al. (2024). Complement Activation Is Associated With Disease Severity in Multiple Sclerosis [Journal-article]. Neurology: Neuroimmunology and NeuroInflammation, 11(2). https://doi.org/10.1212/NXI.0000000000200212

Papadopoulou, A., Pfister, A., Tsagkas, C., Gaetano, L., Sellathurai, S., D’Souza, M., Cerdá-Fuertes, N., Gugleta, K., Descoteaux, M., Chakravarty, M. M., Fuhr, P., Kappos, L., Granziera, C., Magon, S., Sprenger, T., & Hardmeier, M. (2024). Visual evoked potentials in multiple sclerosis: P100 latency and visual pathway damage including the lateral geniculate nucleus. Clinical Neurophysiology, 161, 122–132. https://doi.org/10.1016/j.clinph.2024.02.020

Pontillo, Giuseppe, Prados, Ferran, Colman, Jordan, Kanber, Baris, Abdel-Mannan, Omar, Al-Araji, Sarmad, Bellenberg, Barbara, Bianchi, Alessia, Bisecco, Alvino, Brownlee, Wallace J., Brunetti, Arturo, Cagol, Alessandro, Calabrese, Massimiliano, Castellaro, Marco, Christensen, Ronja, Cocozza, Sirio, Colato, Elisa, Collorone, Sara, Cortese, Rosa, et al. (2024). Disentangling Neurodegeneration From Aging in Multiple Sclerosis Using Deep Learning: The Brain-Predicted Disease Duration Gap. Neurology, 103. https://doi.org/10.1212/WNL.0000000000209976

Sanabria-Diaz, Gretel, Cagol, Alessandro, Lu, Po-Jui, Barakovic, Muhamed, Ocampo-Pineda, Mario, Chen, Xinjie, Weigel, Matthias, Ruberte, Esther, Siebenborn, Nina de Oliveira S., Galbusera, Riccardo, Schädelin, Sabine, Benkert, Pascal, Kuhle, Jens, Kappos, Ludwig, Melie-Garcia, Lester, & Granziera, Cristina. (2024). Advanced MRI Measures of Myelin and Axon Volume Identify Repair in Multiple Sclerosis. Annals of Neurology. https://doi.org/10.1002/ana.27102

Steinegger, L., Nierobisch, N., De Vere-Tyndall, A., Schreiner, B., Roth, P., Kappos, L., Kana, V., & Herwerth, M. (2024). Acute leukoencephalopathy associated with daratumumab treatment in POEMS syndrome: a case report. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1451693

Diouf I, Malpas CB, Sharmin S, Roos I, Horakova D, Kubala Havrdova E, Patti F, Shaygannejad V, Ozakbas S, Eichau S, Onofrj M, Lugaresi A, Alroughani R, Prat A, Duquette P, Terzi M, Boz C, Grand’Maison F, Sola P, et al. (2023). Effectiveness of multiple disease-modifying therapies in relapsing-remitting multiple sclerosis: Causal inference to emulate a multiarm randomised trial. Journal of Neurology, Neurosurgery and Psychiatry, 94(12), 1004–1011. https://doi.org/10.1136/jnnp-2023-331499

Hauser, S. L., Kappos, L., Montalban, X., Chognot, C., Jessop, N., Kadner, K., Pradhan, A., Incera, E., & Wolinsky, J. (2023). Safety of Ocrelizumab in Multiple Sclerosis: Updated Analysis in Patients with Relapsing and Primary Progressive Multiple Sclerosis. 80. https://doi.org/10.1016/j.msard.2023.105308

Montalban, X., Vermersch, P., Arnold, D. L., Bar-Or, A., Cree, B. A. C., Cross, A., Havrdova, E. K., Kappos, L., Stuve, O., Wiendl, H., Wolinsky, J., Bolay, C. L., Hyvert, Y., Javor, A., Guehring, H., Tenenbaum, N., & Tomic, D. (2023). Design and Baseline Characteristics of Phase 3, Double-Blind, Randomised Trials Evaluating the Efficacy and Safety of Evobrutinib Versus Teriflunomide in Relapsing Multiple Sclerosis (evolutionRMS 1 and 2) [Elsevier B.V.]. 80. https://doi.org/10.1016/j.msard.2023.105328

Galbusera, Riccardo, Bahn, Erik, Weigel, Matthias, Schaedelin, Sabine, Franz, Jonas, Lu, Po-Jui, Barakovic, Muhamed, Melie-Garcia, Lester, Dechent, Peter, Lutti, Antoine, Sati, Pascal, Reich, Daniel S., Nair, Govind, Brück, Wolfgang, Kappos, Ludwig, Stadelmann, Christine, & Granziera, Cristina. (2023). Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis. Brain Pathology, 33(6). https://doi.org/10.1111/bpa.13136

Callegari, I., Oechtering, J., Schneider, M., Perriot, S., Mathias, A., Voortman, M. M., Cagol, A., Lanner, U., Diebold, M., Holdermann, S., Kreiner, V., Becher, B., Granziera, C., Junker, A., Du Pasquier, R., Khalil, M., Kuhle, J., Kappos, L., Sanderson, N., & Derfuss, T. (2023). Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5 [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2023.09.29.560121

Hauser S.L., Kappos L., Bar-Or A., Wiendl H., Paling D., Williams M., Gold R., Chan A., Milo R., Das Gupta A., Karlsson G., Sullivan R., Graham G., Merschhemke M., Haring D.A., & Vermersch P. (2023). The Development of Ofatumumab, a Fully Human Anti-CD20 Monoclonal Antibody for Practical Use in Relapsing Multiple Sclerosis Treatment. Neurology and Therapy, 12(5), 1491–1515. https://doi.org/10.1007/s40120-023-00518-0

Hauser, S. L., Zielman, R., Das Gupta, A., Xi, J., Stoneman, D., Karlsson, G., Robertson, D., Cohen, J. A., & Kappos, L. (2023). Efficacy and safety of four-year ofatumumab treatment in relapsing multiple sclerosis: The ALITHIOS open-label extension. Multiple Sclerosis Journal, 29(11-12), 1452–1464. https://doi.org/10.1177/13524585231195346

Harding-Forrester, Sam, Roos, Izanne, Nguyen, Ai-Lan, Malpas, Charles B, Diouf, Ibrahima, Moradi, Nahid, Sharmin, Sifat, Izquierdo, Guillermo, Eichau, Sara, Patti, Francesco, Horakova, Dana, Kubala Havrdova, Eva, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grand’Maison, Francois, Onofrj, Marco, Lugaresi, Alessandra, Grammond, Pierre, et al. (2023). Disability accrual in primary and secondary progressive multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 94(9), 707–717. https://doi.org/10.1136/jnnp-2022-330726

Bar-Or, Amit, Thanei, Gian-Andrea, Harp, Christopher, Bernasconi, Corrado, Bonati, Ulrike, Cross, Anne H., Fischer, Saloumeh, Gaetano, Laura, Hauser, Stephen L., Hendricks, Robert, Kappos, Ludwig, Kuhle, Jens, Leppert, David, Model, Fabian, Sauter, Annette, Koendgen, Harold, Jia, Xiaoming, & Herman, Ann E. (2023). Blood neurofilament light levels predict non-relapsing progression following anti-CD20 therapy in relapsing and primary progressive multiple sclerosis: findings from the ocrelizumab randomised, double-blind phase 3 clinical trials. eBioMedicine, 93. https://doi.org/10.1016/j.ebiom.2023.104662

Pless S, Woelfle T, Naegelin Y, Lorscheider J, Wiencierz A, Reyes Ó, Calabrese P, & Kappos L. (2023). Assessment of cognitive performance in multiple sclerosis using smartphone-based training games: a feasibility study. Journal of Neurology, 270(7), 3451–3463. https://doi.org/10.1007/s00415-023-11671-9

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