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Prof. Dr. med. Marten Trendelenburg

Department of Biomedicine
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Kleer, Jessica S., Klehr, Juliane, Dubler, Denise, Infanti, Laura, Chizzolini, Carlo, Huynh-Do, Uyen, Ribi, Camillo, & Trendelenburg, Marten. (2024). Factor H-related protein 1 in systemic lupus erythematosus [Journal-article]. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1447991
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Eckardt, Henrik, Bless, Nicolas, Heijnen, Ingmar, Morgenstern, Mario, Nehring, Josephine, Kieninger-Gräfitsch, Andrea, Bouchenaki, Martine, Durandin, Vanessa, Purschke, Silke, Schmidt, Ina, Kouba, Loraine Pascale, Trendelenburg, Marten, & Potlukova, Eliska. (2024). Major low-energy trauma results in non-specific immunoglobulin generation without evidence for specific autoantibody production: A prospective cohort study [Journal-article]. Scandinavian Journal of Immunology, 99. https://doi.org/10.1111/sji.13368
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Isayeva, Ganna, Rumora, Klara, Potlukova, Eliska, Leibfarth, Jan-Philipp, Schäfer, Ibrahim, Bartha, Zsofia, Zellweger, Michael J., Trendelenburg, Marten, Hejlesen, Trine Korsgaard, Hansen, Annette Gudmann, Thiel, Steffen, & Mueller, Christian. (2024). Diagnostic and prognostic value of mannan-binding lectin associated protein (MAp19) for functionally relevant coronary artery disease. Clinica Chimica Acta, 558. https://doi.org/10.1016/j.cca.2024.119668
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Moser, Stephan, Araschmid, Laura, Panagiotou, Anneza, Bonati, Leo H., Breidthardt, Tobias, Fahrni, Gregor, Kaiser, Christoph, Jeger, Raban, Trendelenburg, Marten, & Osthoff, Michael. (2024). Association of Endothelial Cell Activation with Acute Kidney Injury during Coronary Angiography and the Influence of Recombinant Human C1 Inhibitor—A Secondary Analysis of a Randomized, Placebo-Controlled, Double-Blind Trial. Biomedicines, 12. https://doi.org/10.3390/biomedicines12091956
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Oechtering, Johanna, Stein, Kerstin, Schaedelin, Sabine A., Maceski, Aleksandra M., Orleth, Annette, Meier, Stephanie, Willemse, Eline, Qureshi, Ferhan, Heijnen, Ingmar, Regeniter, Axel, Derfuss, Tobias, Benkert, Pascal, D’Souza, Marcus, Limberg, Marguerite, Fischer-Barnicol, Bettina, Achtnichts, Lutz, Mueller, Stefanie, Salmen, Anke, Lalive, Patrice H., et al. (2024). Complement Activation Is Associated With Disease Severity in Multiple Sclerosis [Journal-article]. Neurology: Neuroimmunology and NeuroInflammation, 11(2). https://doi.org/10.1212/NXI.0000000000200212
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Schulz, Kristina, Donat, Claudia, Punjabi, Mukesh, Glatz, Katharina, Kaufmann, Beat, & Trendelenburg, Marten. (2023). Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery [Journal-article]. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1265387
Breillat P, Jachiet M, Ditchi Y, Lenormand C, Costedoat-Chalumeau N, Mathian A, Moguelet P, Duriez P, Trendelenburg M, Huynh-Do U, Chizzolini C, Beuvon C, Roy-Peaud F, Bouaziz JD, Barbaud A, Francès C, Mékinian A, Fain O, Amoura Z, et al. (2023). Cutaneous vasculitis occurring in the setting of systemic lupus erythematosus: a multicentre cohort study. Rheumatology (United Kingdom), 62(6), 2189–2196. https://doi.org/10.1093/rheumatology/keac566
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Gross, Sebastian, Becker, Christoph, Beck, Katharina, Memma, Valentina, Gaab, Jens, Schütz, Philipp, Leuppi, Jörg D., Schaefert, Rainer, Langewitz, Wolf, Trendelenburg, Marten, Breidthardt, Tobias, Eckstein, Jens, Osthoff, Michael, Bassetti, Stefano, & Hunziker, Sabina. (2023). Occurrence of sensitive topics during ward round: An ancillary analysis of the BEDSIDE-OUTSIDE trial. BMJ Open, 13. https://doi.org/10.1136/bmjopen-2023-073584
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Isayeva, Ganna, Potlukova, Eliska, Rumora, Klara, Lopez Ayala, Pedro, Kurun, Atakan, Leibfarth, Jan-Philipp, Schäfer, Ibrahim, Michel, Evita, Pesen, Kaan, Zellweger, Michael J., Trendelenburg, Marten, Hejlesen, Trine Korsgaard, Hansen, Annette Gudmann, Thiel, Steffen, & Mueller, Christian. (2023). Diagnostic and prognostic value of H-ficolin for functionally relevant coronary artery disease. Clinica Chimica Acta, 551. https://doi.org/10.1016/j.cca.2023.117582
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Kleer, Jessica S., Skattum, Lillemor, Dubler, Denise, Fischer, Ingeborg, Zgraggen, Armin, Mundwiler, Esther, Kim, Min Jeong, & Trendelenburg, Marten. (2023). Complement C1s deficiency in a male Caucasian patient with systemic lupus erythematosus: a case report. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1257525
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Mihailovic, Jelena, Ribi, Camillo, Chizzolini, Carlo, Trendelenburg, Marten, Von Kempis, Johannes, Dahdal, Suzan, Huynh-Do, Uyen, Comte, Denis, Eisenberger, Ute, Hauser, Thomas, Roux-Lombard, Pascale, Rubbert-Roth, Andrea, & Steiner, Urs. (2023). Worse cardiovascular and renal outcome in male SLE patients. Scientific Reports, 13. https://doi.org/10.1038/s41598-023-45171-7
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Schulz, Kristina, Donat, Claudia, Punjabi, Mukesh, Glatz, Katharina, Kaufmann, Beat, & Trendelenburg, Marten. (2023). Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1265387
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Urwyler, Pascal, Leimbacher, Marina, Charitos, Panteleimon, Moser, Stephan, Heijnen, Ingmar A. F. M., Trendelenburg, Marten, Thoma, Reto, Sumer, Johannes, Camacho-Ortiz, Adrián, Bacci, Marcelo R., Huber, Lars C., Stüssi-Helbling, Melina, Albrich, Werner C., Sendi, Parham, & Osthoff, Michael. (2023). Recombinant C1 inhibitor in the prevention of severe COVID-19: a randomized, open-label, multi-center phase IIa trial. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1255292
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Bruni F, Charitos P, Lampart M, Moser S, Siegemund M, Bingisser R, Osswald S, Bassetti S, Twerenbold R, Trendelenburg M, Rentsch KM, & Osthoff M. (2022). Complement and endothelial cell activation in COVID-19 patients compared to controls with suspected SARS-CoV-2 infection: A prospective cohort study. Frontiers in Immunology, 13, 941742. https://doi.org/10.3389/fimmu.2022.941742
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Schulz K., & Trendelenburg M. (2022). C1q as a target molecule to treat human disease: What do mouse studies teach us? Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.958273
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Capoferri G, Daikeler T, Mühleisen B, Trendelenburg M, & Müller S. (2022). Cutaneous leukocytoclastic vasculitis secondary to COVID-19 infection leading to extensive skin necrosis. Clinics in Dermatology, 40(4), 397–401. https://doi.org/10.1016/j.clindermatol.2022.02.013
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Costa A.E., Bernasconi N.S., Trendelenburg M., & Schunemann M.J. (2022). Severe myopathy complicating multisystem inflammatory syndrome in adults (MIS-A) in a young man. BMJ Case Reports, 15(7). https://doi.org/10.1136/bcr-2022-250054
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Gross S, Beck K., Becker C, Gamp M, Mueller J, Loretz N., Amacher SA, Bohren C, Gaab J, Schuetz P, Mueller B, Fux C.A., Leuppi J.D., Schaefert R, Langewitz W, Trendelenburg M, Breidthardt T, Eckstein J, Osthoff M, et al. (2022). Perception of physicians and nursing staff members regarding outside versus bedside ward rounds: Ancillary analysis of the randomised BEDSIDE-OUTSIDE trial. Swiss Medical Weekly, 152(3-4). https://doi.org/10.4414/smw.2022.w30112
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Kleer JS, Rabatscher PA, Weiss J., Leonardi J, Vogt SB, Kieninger-Grafitsch A., Chizzolini C., Huynh-Do U., Ribi C., & Trendelenburg M. (2022). Epitope-Specific Anti-C1q Autoantibodies in Systemic Lupus Erythematosus. Frontiers in Immunology, 12, 761395. https://doi.org/10.3389/fimmu.2021.761395
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Chasset F., Mathian A., Dorgham K., Ribi C., Trendelenburg M., Huynh-Do U., Roux-Lombard P., Courvoisier D.S., Amoura Z., Gorochov G., & Chizzolini C. (2022). Serum interferon-α levels and IFN type I-stimulated genes score perform equally to assess systemic lupus erythematosus disease activity. Annals of the Rheumatic Diseases, 81(6), 901–903. https://doi.org/10.1136/annrheumdis-2021-221835
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Huebner, Simona Tabea, Henny, Simona, Giezendanner, Stéphanie, Brack, Thomas, Brutsche, Martin, Chhajed, Prashant, Clarenbach, Christian, Dieterle, Thomas, Egli, Adrian, Frey, Martin, Heijnen, Ingmar, Irani, Sarosh, Sievi, Noriane Andrina, Thurnheer, Robert, Trendelenburg, Marten, Kohler, Malcolm, Leuppi-Taegtmeyer, Anne Barbara, & Leuppi, Joerg Daniel. (2022). Prediction of Acute COPD Exacerbation in the Swiss Multicenter COPD Cohort Study (TOPDOCS) by Clinical Parameters, Medication Use, and Immunological Biomarkers. Respiration, 101, 441–454. https://doi.org/10.1159/000520196
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Rabatscher P.A., & Trendelenburg M. (2022). Anti-C1q autoantibodies from systemic lupus erythematosus patients enhance CD40–CD154-mediated inflammation in peripheral blood mononuclear cells in vitro. Clinical and Translational Immunology, 11(8). https://doi.org/10.1002/cti2.1408
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Urwyler, Pascal, Moser, Stephan, Trendelenburg, Marten, Sendi, Parham, & Osthoff, Michael. (2022). Targeting thromboinflammation in COVID-19 – A narrative review of the potential of C1 inhibitor to prevent disease progression. Molecular Immunology, 150, 99–113. https://doi.org/10.1016/j.molimm.2022.08.008
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Vogt S, Leuppi JD, Schuetz P, Mueller B, Volken C, Dräger S, Trendelenburg M, Rutishauser J, Rutishauser J, & Osthoff M. (2021). Association of mannose-binding lectin, ficolin-2 and immunoglobulin concentrations with future exacerbations in patients with chronic obstructive pulmonary disease: secondary analysis of the randomized controlled REDUCE trial. Respiratory Research, 22(1), 227. https://doi.org/10.1186/s12931-021-01822-9
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Charitos P., Heijnen IAFM, Egli A, Bassetti S., Trendelenburg M., & Osthoff M. (2021). Functional Activity of the Complement System in Hospitalized COVID-19 Patients: A Prospective Cohort Study. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.765330
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Becker C, Gamp M., Schuetz P., Beck K., Vincent A, Hochstrasser S., Metzger K., Widmer M., Thommen E, Mueller B, Fux CA, Leuppi JD, Schaefert R, Langewitz W., Trendelenburg M., Breidthardt T, Eckstein J, Osthoff M, Bassetti S., & Hunziker S. (2021). Effect of bedside compared with outside the room patient case presentation on patients’ knowledge about their medical care: A randomized, controlled, multicenter trial. Annals of Internal Medicine, 174(9), 1282–1292. https://doi.org/10.7326/m21-0909
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Kiener S., Ribi C., Keller I., Chizzolini C., Trendelenburg M., Huynh-Do U., von Kempis J., & Leeb T. (2021). Variants affecting the C-terminal tail of UNC93B1 are not a common risk factor for systemic lupus erythematosus. Genes, 12(8). https://doi.org/10.3390/genes12081268
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Trendelenburg M. (2021). Autoantibodies against complement component C1q in systemic lupus erythematosus. Clinical and Translational Immunology, 10(4). https://doi.org/10.1002/cti2.1279
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Urwyler, Pascal, Charitos, Panteleimon, Moser, Stephan, Heijnen, Ingmar A. F. M., Trendelenburg, Marten, Thoma, Reto, Sumer, Johannes, Camacho-Ortiz, Adrián, Bacci, Marcelo R., Huber, Lars C., Stüssi-Helbling, Melina, Albrich, Werner C., Sendi, Parham, & Osthoff, Michael. (2021). Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of severe SARS-CoV-2 infection in hospitalized patients with COVID-19: A structured summary of a study protocol for a randomized, parallel-group, open-label, multi-center pilot trial (PROTECT-COVID-19). Trials, 22(1). https://doi.org/10.1186/s13063-020-04976-x
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Kieninger-Gräfitsch A, Vogt S, Ribi C, Dubler D, Chizzolini C, Huynh-Do U, Osthoff M, & Trendelenburg M. (2020). No association of complement mannose-binding lectin deficiency with cardiovascular disease in patients with Systemic Lupus Erythematosus. Scientific Reports, 10(1), 3693. https://doi.org/10.1038/s41598-020-60523-3
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Chasset F, Ribi C, Trendelenburg M, Huynh-Do U, Roux-Lombard P, Courvoisier DS, Chizzolini C, & Swiss SLE Cohort Study (SSCS. (2020). Identification of highly active systemic lupus erythematosus by combined type I interferon and neutrophil gene scores vs classical serologic markers. Rheumatology (United Kingdom), 59(11), 3468–3478. https://doi.org/10.1093/rheumatology/keaa167
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Strasser DS, Froidevaux S, Sippel V, Gerossier E, Grieder U, Pierlot GM, Kieninger-Graefitsch A, Vezzali E, Stalder AK, Renault B, Ryge J, Hart A, Mentzel U, Groenen PMA, Keller MP, Trendelenburg M, Martinic MM, & Murphy MJ. (2020). Preclinical to clinical translation of cenerimod, a novel S1P 1 receptor modulator, in systemic lupus erythematosus. RMD Open, 6(2). https://doi.org/10.1136/rmdopen-2020-001261
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Donat C, Kölm R, Csorba K, Tuncer E, Tsakiris DA, & Trendelenburg M. (2020). Complement C1q Enhances Primary Hemostasis. Frontiers in Immunology, 11, 1522. https://doi.org/10.3389/fimmu.2020.01522
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Panagiotou A, Trendelenburg M, Heijnen IAFM, Moser S, Bonati LH, Breidthardt T, Fahrni G, Kaiser C, Jeger R, & Osthoff M. (2020). A Randomized Trial of Recombinant Human C1-Esterase-Inhibitor in the Prevention of Contrast-Induced Kidney Injury. JACC: Cardiovascular Interventions, 13(7), 833–842. https://doi.org/10.1016/j.jcin.2019.11.021
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Nigolian H, Ribi C, Courvoisier DS, Pagano S, Alvarez M, Trendelenburg M, Huynh-Do U, Vuilleumier N, Dayer JM, Chizzolini C, & Roux-Lombard P. (2020). Anti-apolipoprotein A-1 autoantibodies correlate with disease activity in systemic lupus erythematosus. Rheumatology (United Kingdom), 59(3), 534–544. https://doi.org/10.1093/rheumatology/kez306
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Sarcevic, Jelena, Cavelti-Weder, Claudia, Berger, T. Christoph, & Trendelenburg, Marten. (2020). Secondary Antibody Deficiency Due to Endogenous Hypercortisolism. Frontiers in Immunology, 11, 1435. https://doi.org/10.3389/fimmu.2020.01435
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Urwyler, Pascal, Moser, Stephan, Charitos, Panteleimon, Heijnen, Ingmar A. F. M., Rudin, Melanie, Sommer, Gregor, Giannetti, Bruno M., Bassetti, Stefano, Sendi, Parham, Trendelenburg, Marten, & Osthoff, Michael. (2020). Treatment of COVID-19 With Conestat Alfa, a Regulator of the Complement, Contact Activation and Kallikrein-Kinin System. Frontiers in Immunology, 11. https://doi.org/10.3389/fimmu.2020.02072
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Vogt, Severin, Trendelenburg, Marten, Tamm, Michael, Stolz , Daiana, Hostettler, Katrin Esther, & Osthoff, Michael. (2020). Local and Systemic Concentration of Pattern Recognition Receptors of the Lectin Pathway of Complement in a Cohort of Patients With Interstitial Lung Diseases. Frontiers in Immunology, 11, 562564. https://doi.org/10.3389/fimmu.2020.562564
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Donat C, Thanei S, & Trendelenburg M. (2019). Binding of von Willebrand Factor to Complement C1q Decreases the Phagocytosis of Cholesterol Crystals and Subsequent IL-1 Secretion in Macrophages. Frontiers in Immunology, 10, 2712. https://doi.org/10.3389/fimmu.2019.02712
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Friebus-Kardash J, Trendelenburg M, Eisenberger U, Ribi C, Chizzolini C, Huynh-Do U, Lang KS, Wilde B, Kribben A, Witzke O, Dolff S, & Hardt C. (2019). Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis. BMC Nephrology, 20(1), 430. https://doi.org/10.1186/s12882-019-1623-4
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Csorba K, Schirmbeck LA, Tuncer E, Ribi C, Roux-Lombard P, Chizzolini C, Huynh-Do U, Vanhecke D, & Trendelenburg M. (2019). Anti-C1q Antibodies as Occurring in Systemic Lupus Erythematosus Could Be Induced by an Epstein-Barr Virus-Derived Antigenic Site. Frontiers in Immunology, 10, 2619. https://doi.org/10.3389/fimmu.2019.02619
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Troldborg A, Steffensen R, Trendelenburg M, Hauser T, Winther KG, Hansen AG, Stengaard-Pedersen K, Voss A, & Thiel S. (2019). Ficolin-3 Deficiency Is Associated with Disease and an Increased Risk of Systemic Lupus Erythematosus. Journal of Clinical Immunology, 39(4), 421–429. https://doi.org/10.1007/s10875-019-00627-2
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Pröbstel AK, Thanei M, Erni B, Lecourt AC, Branco L, André R, Roux-Lombard P, Koenig KF, Huynh-Do U, Ribi C, Chizzolini C, Kappos L, Trendelenburg M, Derfuss T, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2019). Association of antibodies against myelin and neuronal antigens with neuroinflammation in systemic lupus erythematosus. Rheumatology (United Kingdom), 58(5), 908–913. https://doi.org/10.1093/rheumatology/key282
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Osthoff M, Jaeger VK, Heijnen IAFM, Trendelenburg M, Jordan S, Distler O, & Walker U.A. (2019). Role of lectin pathway complement proteins and genetic variants in organ damage and disease severity of systemic sclerosis: A cross-sectional study. Arthritis Research and Therapy, 21(1). https://doi.org/10.1186/s13075-019-1859-1
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Marchetti T, Ribi C, Perneger T, Trendelenburg M, Huynh-Do U, de Moerloose P, & Chizzolini C. (2018). Prevalence, persistence and clinical correlations of classic and novel antiphospholipid antibodies in systemic lupus erythematosus. Rheumatology (Oxford, England), 57(8), 1350–1357. https://doi.org/10.1093/rheumatology/key095
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Troldborg A, Thiel S, Trendelenburg M, Friebus-Kardash J, Nehring J, Steffensen R, Hansen SWK, Laska MJ, Deleuran B, Jensenius JC, Voss A, & Stengaard-Pedersen K. (2018). The Lectin Pathway of Complement Activation in Patients with Systemic Lupus Erythematosus. The Journal of rheumatology, 45(8), 1136–1144. https://doi.org/10.3899/jrheum.171033
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Burkard T, Trendelenburg M, Daikeler T, Hess C, Bremerich J, Haaf P, Buser P, & Zellweger MJ. (2018). The heart in systemic lupus erythematosus - A comprehensive approach by cardiovascular magnetic resonance tomography. PloS One, 13(10), e0202105. https://doi.org/10.1371/journal.pone.0202105
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Dahdal S, Devetzis V, Chalikias G, Tziakas D, Chizzolini C, Ribi C, Trendelenburg M, Eisenberger U, Hauser T, Pasch A, Huynh-Do U, Arampatzis S, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2018). Serum calcification propensity is independently associated with disease activity in systemic lupus erythematosus. PloS one, 13(1), e0188695. https://doi.org/10.1371/journal.pone.0188695
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Friebus-Kardash J, Branco L, Ribi C, Chizzolini C, Huynh-Do U, Dubler D, Roux-Lombard P, Dolff S, Kribben A, Eisenberger U, & Trendelenburg M. (2018). Immune complexes containing serum B-cell activating factor and immunoglobulin G correlate with disease activity in systemic lupus erythematosus. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 33(1), 54–64. https://doi.org/10.1093/ndt/gfx220
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Panagiotou A, Trendelenburg M, & Osthoff M. (2018). The Lectin Pathway of Complement in Myocardial Ischemia/Reperfusion Injury-Review of Its Significance and the Potential Impact of Therapeutic Interference by C1 Esterase Inhibitor. Frontiers in immunology, 9, 1151. https://doi.org/10.3389/fimmu.2018.01151
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Thanei S, Theron M, Silva AP, Reis B, Branco L, Schirmbeck L, Kolb FA, Haap W, Schindler T, & Trendelenburg M. (2017). Cathepsin S inhibition suppresses autoimmune-triggered inflammatory responses in macrophages. Biochemical pharmacology, 146, 151–164. https://doi.org/10.1016/j.bcp.2017.10.001
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Osthoff M, Walder B, Delhumeau C, Trendelenburg M, & Turck N. (2017). Association of Lectin Pathway Protein Levels and Genetic Variants Early after Injury with Outcomes after Severe Traumatic Brain Injury: A Prospective Cohort Study. Journal of Neurotrauma, 34(17), 2560–2566. https://doi.org/10.1089/neu.2016.4941
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Huber, Xaver, Degen, Lukas, Muenst, Simone, & Trendelenburg, Marten. (2017). Primary intestinal lymphangiectasia in an elderly female patient: A case report on a rare cause of secondary immunodeficiency. Medicine, 96(31), e7729. https://doi.org/10.1097/md.0000000000007729
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Kofler T, Yueksel F, Dirnhofer S, Donath MY, & Trendelenburg M. (2017). [Abdominal pain and hypertension in a 55-year-old male patient]. Der Internist, 58(4), 397–401. https://doi.org/10.1007/s00108-016-0170-3
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Chaigne B, Chizzolini C, Perneger T, Trendelenburg M, Huynh-Do U, Dayer E, Stoll T, von Kempis J, Ribi C, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2017). Impact of disease activity on health-related quality of life in systemic lupus erythematosus - a cross-sectional analysis of the Swiss Systemic Lupus Erythematosus Cohort Study (SSCS). BMC immunology, 18(1), 17. https://doi.org/10.1186/s12865-017-0200-5
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Thanei S, & Trendelenburg M. (2017). Anti-C1q autoantibodies from patients with systemic lupus erythematosus induce C1q production by macrophages. Journal of leukocyte biology, 101(2), 481–491. https://doi.org/10.1189/jlb.3a1215-535r
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Stegert M, Bock M, & Trendelenburg M. (2015). Clinical presentation of human C1q deficiency: How much of a lupus? Molecular immunology, 67(1), 3–11. https://doi.org/10.1016/j.molimm.2015.03.007
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Ribi C, Trendelenburg M, Gayet-Ageron A, Cohen C, Dayer E, Eisenberger U, Hauser T, Hunziker T, Leimgruber A, Lindner G, Koenig K, Otto P, Spertini F, Stoll T, Von Kempis J, Chizzolini C, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2014). The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - Cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland. Swiss Medical Weekly, 144, w13990. https://doi.org/10.4414/smw.2014.13990
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Scharein P, & Trendelenburg M. (2013). Critical incidents in a tertiary care clinic for internal medicine. BMC research notes, 6, 276. https://doi.org/10.1186/1756-0500-6-276
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Osthoff M, & Trendelenburg M. (2013). Impact of mannose-binding lectin deficiency on radiocontrast-induced renal dysfunction. BioMed Research International, 2013(1), 962695. https://doi.org/10.1155/2013/962695
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Vanhecke D., Roumenina, Lubka T., Wan H., Osthoff, Michael, Schaller M., & Trendelenburg M. (2012). Identification of a major linear C1q epitope allows detection of systemic lupus erythematosus anti-C1q antibodies by a specific peptide-based enzyme-linked immunosorbent assay. Arthritis and Rheumatism, 64(11), 3706–3714. https://doi.org/10.1002/art.34605
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Osthoff M, Piezzi V, Klima T, Christ A, Marana I, Hartwiger S, Breidthardt T, Marenzi G, Trendelenburg M, & Mueller C. (2012). Impact of mannose-binding lectin deficiency on radiocontrast-induced renal dysfunction: a post-hoc analysis of a multicenter randomized controlled trial. BMC nephrology, 13, 99. https://doi.org/10.1186/1471-2369-13-99
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Trendelenburg M. (2012). Anti-C1q antibodies as a diagnostic marker of proliferative lupus nephritis: comment on the article by Katsumata et al. (Patent No. 1). 64(1), Article 1. https://doi.org/10.1002/art.33384
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Osthoff M, Katan M., Fluri F., Schuetz P, Bingisser R, Kappos L, Steck AJ, Engelter ST, Mueller B, Christ-Crain M, & Trendelenburg M. (2011). Mannose-binding lectin deficiency is associated with smaller infarction size and favorable outcome in ischemic stroke patients. PLoS ONE, 6(6). https://doi.org/10.1371/journal.pone.0021338
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Osthoff, M., Katan, M., Fluri, F., Schuetz, P., Bingisser, R., Kappos, L., Steck, A. J., Engelter, S. T., Müller, B., Christ-Crain, M., & Trendelenburg, M. (2011). Mannose-binding lectin deficiency is associated with smaller infarction size and favorable outcome in ischemic stroke patients. PLoS ONE, 6(6), e21338. https://doi.org/10.3410/f.717949101.793454250
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Chizzolini C, Cohen CD, Eisenberger U, Hauser T, Hunziker T, Leimgruber A, Pechula M, Ribi C, Stoll T, Trendelenburg M, & Groupe de travail de la SSCS. (2009). [Towards the Swiss systemic lupus erythematosus cohort study (SSCS)]. Revue medicale suisse, 5(199), 808–811.
Chizzolini, Carlo, Cohen, Clemens D, Eisenberger, Ute, Hauser, Thomas, Hunziker, Thomas, Leimgruber, Annette, Pechula, Martina, Ribi, Camillo, Stoll, Thomas, Trendelenburg, Marten, & Groupe de travail de la SSCS. (2009). Création d’unecohorte suisse de patients lupiques : the Swiss systemic lupus erythematosus cohort study (SSCS). Revue Médicale Suisse : Revue Officielle de La Société Médicale de La Suisse Romande ... [Et Al.], 5(199), 808–811.
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Arici B., & Trendelenburg M. (2008). Successful treatment of thrombotic thrombocytopenic purpura (TTP) with Rituximab Erfolgreiche behandlung einer thrombotisch thrombozytopenischen purpura mit rituximab. Therapeutische Umschau, 65(12), 710–712. https://doi.org/10.1024/0040-930.65.12.710
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Trendelenburg M. (2008). From smolder to blaze - Pathogenesis and mechanisms of inflammation Vom glimmen zur glut - Pathogenese und mechanismen entzündlicher prozesse. Aktuelle Ernahrungsmedizin, 33(SUPPL. 1). https://doi.org/10.1055/s-2007-986416
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Ottl T, & Trendelenburg M. (2008). [Cryoglobulinemia]. Therapeutische Umschau. Revue therapeutique, 65(5), 253–258. https://doi.org/10.1024/0040-5930.65.5.253
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Ottl,T, & Trendelenburg,M. (2008). [Cryoglobulinemia]. Therapeutische Umschau, 65(5), 253–258. https://doi.org/10.1024/0040-5930.65.5.253
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Krähenbuhl S, Brauchli Y, Kummer O, Bodmer M, Trendelenburg M, Drewe J, & Haschke M. (2007). Acute liver failure in two patients with regular alcohol consumption ingesting paracetamol at therapeutic dosage. Digestion, 75(4), 232–237. https://doi.org/10.1159/000111032
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Manuel O, Tarr PE, Venetz JP, Trendelenburg M, Meylan PR, & Pascual M. (2007). Meningococcal disease in a kidney transplant recipient with mannose-binding lectin deficiency. Transplant infectious disease : an official journal of the Transplantation Society, 9(3), 214–218. https://doi.org/10.1111/j.1399-3062.2006.00191.x
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Trendelenburg M. (2007). Complement inhibition by anti-C5 antibodies - From bench to bedside and back again. Swiss Medical Weekly, 137(29-30), 413–417. https://doi.org/10.4414/smw.2007.11792
Trendelenburg M. (2007). Complement inhibition by anti-C5 antibodies - From bench to bedside and back again. Swiss Medical Weekly, 137(29-30), 413–417.
Trendelenburg M, & Schifferli JA. (2007). Rituximab in a patient with Hyper-IgE syndrome. Archives of dermatology, 143(6), 807–808. https://doi.org/10.1001/archderm.143.6.807
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Trendelenburg M. (2007). [Autoantibodies--physiological phenomenon or manifestation of disease?]. Praxis, 96(10), 379–382. https://doi.org/10.1024/1661-8157.96.10.379
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Manuel O, Pascual M, Trendelenburg M, & Meylan PR. (2007). Association between mannose-binding lectin deficiency and cytomegalovirus infection after kidney transplantation. Transplantation, 83(3), 359–362. https://doi.org/10.1097/01.tp.0000251721.90688.c2
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Trendelenburg M, Lopez-Trascasa M, Potlukova E, Moll S, Regenass S, Frémeaux-Bacchi V, Martinez-Ara J, Jancova E, Picazo ML, Honsova E, Tesar V, Sadallah S, & Schifferli J. (2006). High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 21(11), 3115–3121. https://doi.org/10.1093/ndt/gfl436
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Schirinzi R, Lantin JP, Frémeaux-Bacchi V, Schifferli JA, & Trendelenburg M. (2006). [Combined-heterozygous deficiency of complement C7 in a patient with recurrent meningitis]. Medizinische Klinik (Munich, Germany : 1983), 101(8), 655–658. https://doi.org/10.1007/s00063-006-1070-4
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Kozyro I, Perahud I, Sadallah S, Sukalo A, Titov L, Schifferli J, & Trendelenburg M. (2006). Clinical value of autoantibodies against C1q in children with glomerulonephritis. Pediatrics, 117(5), 1663–1668. https://doi.org/10.1542/peds.2005-1148
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Saadoun D, Sadallah S, Trendelenburg M, Limal N, Sene D, Piette JC, Schifferli JA, & Cacoub P. (2006). Anti-C1q antibodies in hepatitis C virus infection. Clinical and Experimental Immunology, 145(2), 308–312. https://doi.org/10.1111/j.1365-2249.2006.03153.x
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Trendelenburg M, Fossati-Jimack L, Cortes-Hernandez J, Turnberg D, Lewis M, Izui S, Cook HT, & Botto M. (2005). The role of complement in cryoglobulin-induced immune complex glomerulonephritis. Journal of Immunology, 175(10), 6909–6914. https://doi.org/10.4049/jimmunol.175.10.6909
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Trendelenburg M. (2005). [Pathogenesis of systemic lupus erythematosus (SLE)--the central role of complement]. Therapeutische Umschau. Revue therapeutique, 62(5), 285–291. https://doi.org/10.1024/0040-5930.62.5.285
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Trendelenburg M, Manderson AP, Fossati-Jimack L, Walport MJ, & Botto M. (2004). Monocytosis and accelerated activation of lymphocytes in C1q-deficient autoimmune-prone mice. Immunology, 113(1), 80–88. https://doi.org/10.1111/j.1365-2567.2004.01940.x
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Sadallah S, Hess C., Trendelenburg M., Vedeler C, Lopez-Trascasa M, & Schifferli JA. (2003). Autoantibodies against complement receptor 1 (CD35) in SLE, liver cirrhosis and HIV-infected patients. Clinical and Experimental Immunology, 131(1), 174–181. https://doi.org/10.1046/j.1365-2249.2003.02045.x
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Trendelenburg M, Lutz HU, Tissot JD, Moll S, Hoffmann T, & Schifferli JA. (2003). Cryoglobulin/albumin complexes in a patient with severe autoimmune syndrome. Scandinavian journal of rheumatology, 32(6), 367–373. https://doi.org/10.1080/03009740410005043
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Trendelenburg M, Gregor M, Passweg J, Tichelli A, Tyndall A, & Gratwohl A. (2001). “Altered immunity syndrome”, a distinct entity in long-term bone marrow transplantation survivors? (Patent No. 12). 28(12), Article 12. https://doi.org/10.1038/sj.bmt.1703300
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Moroni G, Trendelenburg M, Del Papa N, Quaglini S, Raschi E, Panzeri P, Testoni C, Tincani A, Banfi G, Balestrieri G, Schifferli JA, Meroni PL, & Ponticelli C. (2001). Anti-C1q antibodies may help in diagnosing a renal flare in lupus nephritis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 37(3), 490–498. https://doi.org/10.1053/ajkd.2001.22071
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Trendelenburg M, Büchner S, Passweg J, Rätz Bravo AR, & Gratwohl A. (2001). Disseminated scabies evolving in a patient undergoing induction chemotherapy for acute myeloblastic leukaemia. Annals of Hematology, 80(2), 116–118. https://doi.org/10.1007/s002770000242
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Trendelenburg M, & Schifferli JA. (2000). [New physiopathological findings in paraproteinemias]. Schweizerische medizinische Wochenschrift, 130(44), 1639–1642.
Trendelenburg M, & Schifferli JA. (2000). [Apoptosis and C1q: possible explanations for the pathogenesis of systemic lupus erythematosus]. Zeitschrift fur Rheumatologie, 59(3), 172–175. https://doi.org/10.1007/s003930070077
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Trendelenburg M, Courvoisier S, Späth PJ, Moll S, Mihatsch M, Itin P, & Schifferli JA. (1999). Hypocomplementemic urticarial vasculitis or systemic lupus erythematosus? American journal of kidney diseases : the official journal of the National Kidney Foundation, 34(4), 745–751. https://doi.org/10.1016/s0272-6386(99)70402-6
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Breitschwerdt B., Goeser T., Tissot J.D., Trendelenburg M., Sis-Kluzik J.M., & Andrassy K. (1999). Hepatitis virus-related and ethanol-induced chronic liver disease with or without cryoglobulins - Is there a difference concerning clinical or laboratory manifestation? Infection, 27(4-5), 248–251. https://doi.org/10.1007/s150100050021
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Trendelenburg M, Hess C, Kondo-Oestreicher M, Tissot JD, Späth P, & Schifferli JA. (1999). Monomeric complement-activating IgG paraproteins. Journal of Immunology, 163(12), 6924–6932. https://doi.org/10.4049/jimmunol.163.12.6924
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Trendelenburg M, Marfurt J, Gerber I, Tyndall A, & Schifferli JA. (1999). Lack of occurrence of severe lupus nephritis among anti-C1q autoantibody-negative patients. Arthritis and rheumatism, 42(1), 187–188. https://doi.org/10.1002/1529-0131(199901)42:1<187::aid-anr24>3.0.co;2-u
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Trendelenburg M, & Schifferli JA. (1998). [Is autoantibody determination in patients with systemic lupus erythematosus useful? Anti-C1q-autoantibody as an example]. Praxis, 87(51-52), 1811–1813.
Infanti L, Spengeler V, Hoffmann T, Favre G, Passweg J, Trendelenburg M, & Tichelli A. (1998). Correction of spurious blood cell counts in a patient with cryoglobulinemia reversed by the use of citrate-anticoagulated blood. Schweizerische Medizinische Wochenschrift, 128(42), 1608–1610.
Trendelenburg M., & Schifferli J.A. (1998). Are measurements of autoantibodies useful in patients with systemic lupus erythematosus? Anti-C1q as an example. Praxis, 87, 1811–1813.
Trendelenburg M, & Schifferli JA. (1998). Cryoglobulins are not essential. Annals of the rheumatic diseases, 57(1), 3–5. https://doi.org/10.1136/ard.57.1.3
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