Prof. Dr. med. Marten Trendelenburg

Potlukova, Eliska, Dubs, Lynn, Huwendiek, Sören, Kassi, Elianne, von Rotz, Matthias, Nehring, Josephine, Etienne, Samuel, Müller, Olivia, Thies, Katharina, Boss, Oliver, Schuenemann, Max, Rohacek, Martin, Bassetti, Stefano, Trendelenburg, Marten, Wilde, Michael, Voigt, Gabriele, Seelmann, Sonja, & Meienberg, Andrea. (2025). A multifaceted early clinical experience course in internal medicine fosters motivation and professional growth from the perspective of first-year medical students. BMC Medical Education, 25. https://doi.org/10.1186/s12909-025-07792-6

Kleer, J. S., Kieninger-Gräfitsch, A., Chizzolini, C., Huynh-Do, U., Ribi, C., & Trendelenburg, M. (2025). Evaluation of the Impact of Anti-C1q Autoantibodies on Cardiovascular Outcomes in Systemic Lupus Erythematosus. Scandinavian Journal of Immunology, 101(5). https://doi.org/10.1111/sji.70028

Oechtering, Johanna, Schaedelin, Sabine Anna, Stein, Kerstin, Maceski, Aleksandra Maleska, Melie-Garcia, Lester, Benkert, Pascal, Cagol, Alessandro, Leber, Selina, Galbusera, Riccardo, Ruberte, Esther, Hu, Wayne, Qureshi, Ferhan, Orleth, Annette, Demuth, Lilian, Willemse, Eline, Heijnen, Ingmar, Regeniter, Axel, Derfuss, Tobias J., Fischer-Barnicol, Bettina, et al. (2025). Aberrant Complement Activation Is Associated With Structural Brain Damage in Multiple Sclerosis. Neurology: Neuroimmunology and NeuroInflammation, 12(2). https://doi.org/10.1212/nxi.0000000000200361

Fritz, A.-S., Trendelenburg, M., & Mutke, M. (2025). Piperacillin/Tazobactam Induced Immune-Mediated Anaemia and Thrombocytopenia [Journal-article]. European Journal of Case Reports in Internal Medicine, 12. https://doi.org/10.12890/2025_005460

Kruta, Jan, Carapito, Raphael, Trendelenburg, Marten, Martin, Thierry, Rizzi, Marta, Voll, Reinhard E., Cavalli, Andrea, Natali, Eriberto, Meier, Patrick, Stawiski, Marc, Mosbacher, Johannes, Mollet, Annette, Santoro, Aurelia, Capri, Miriam, Giampieri, Enrico, Schkommodau, Erik, & Miho, Enkelejda. (2024). Machine learning for precision diagnostics of autoimmunity. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-76093-7

Moser, Stephan, Araschmid, Laura, Panagiotou, Anneza, Bonati, Leo H., Breidthardt, Tobias, Fahrni, Gregor, Kaiser, Christoph, Jeger, Raban, Trendelenburg, Marten, & Osthoff, Michael. (2024). Association of Endothelial Cell Activation with Acute Kidney Injury during Coronary Angiography and the Influence of Recombinant Human C1 Inhibitor—A Secondary Analysis of a Randomized, Placebo-Controlled, Double-Blind Trial. Biomedicines, 12(9). https://doi.org/10.3390/biomedicines12091956

Eckardt, Henrik, Bless, Nicolas, Heijnen, Ingmar, Morgenstern, Mario, Nehring, Josephine, Kieninger-Gräfitsch, Andrea, Bouchenaki, Martine, Durandin, Vanessa, Purschke, Silke, Schmidt, Ina, Kouba, Loraine Pascale, Trendelenburg, Marten, & Potlukova, Eliska. (2024). Major low-energy trauma results in non-specific immunoglobulin generation without evidence for specific autoantibody production: A prospective cohort study. Scandinavian Journal of Immunology, 99(6). https://doi.org/10.1111/sji.13368

Isayeva, Ganna, Potlukova, Eliska, Rumora, Klara, Schäfer, Ibrahim, Trendelenburg, Marten, Korsgaard, T., Hansen, A.G., Thiel, Steffen, & Mueller, Christian. (2024). Diagnostic and Prognostic Value of Complement Lectin Pathway Components (H-ficolin, Mannose-Binding Lectin, and Map19) in Functionally Relevant Coronary Artery Disease (Patent No. 5, Suppl. 276). Swiss Medical Weekly, 154(5, Suppl. 276), Article 5, Suppl. 276. SMW supporting association.

Isayeva, Ganna, Rumora, Klara, Potlukova, Eliska, Leibfarth, Jan-Philipp, Schäfer, Ibrahim, Bartha, Zsofia, Zellweger, Michael J., Trendelenburg, Marten, Hejlesen, Trine Korsgaard, Hansen, Annette Gudmann, Thiel, Steffen, & Mueller, Christian. (2024). Diagnostic and prognostic value of mannan-binding lectin associated protein (MAp19) for functionally relevant coronary artery disease. Clinica Chimica Acta, 558. https://doi.org/10.1016/j.cca.2024.119668

Oechtering, Johanna, Stein, Kerstin, Schaedelin, Sabine A., Maceski, Aleksandra M., Orleth, Annette, Meier, Stephanie, Willemse, Eline, Qureshi, Ferhan, Heijnen, Ingmar, Regeniter, Axel, Derfuss, Tobias, Benkert, Pascal, D’Souza, Marcus, Limberg, Marguerite, Fischer-Barnicol, Bettina, Achtnichts, Lutz, Mueller, Stefanie, Salmen, Anke, Lalive, Patrice H., et al. (2024). Complement Activation Is Associated With Disease Severity in Multiple Sclerosis [Journal-article]. Neurology: Neuroimmunology and NeuroInflammation, 11(2). https://doi.org/10.1212/nxi.0000000000200212

Kleer, Jessica S., Klehr, Juliane, Dubler, Denise, Infanti, Laura, Chizzolini, Carlo, Huynh-Do, Uyen, Ribi, Camillo, & Trendelenburg, Marten. (2024). Factor H-related protein 1 in systemic lupus erythematosus [Journal-article]. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1447991

Mihailovic, Jelena, Ribi, Camillo, Chizzolini, Carlo, Trendelenburg, Marten, Von Kempis, Johannes, Dahdal, Suzan, Huynh-Do, Uyen, Comte, Denis, Eisenberger, Ute, Hauser, Thomas, Roux-Lombard, Pascale, Rubbert-Roth, Andrea, & Steiner, Urs. (2023). Worse cardiovascular and renal outcome in male SLE patients. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-45171-7

Isayeva, Ganna, Potlukova, Eliska, Rumora, Klara, Lopez Ayala, Pedro, Kurun, Atakan, Leibfarth, Jan-Philipp, Schäfer, Ibrahim, Michel, Evita, Pesen, Kaan, Zellweger, Michael J., Trendelenburg, Marten, Hejlesen, Trine Korsgaard, Hansen, Annette Gudmann, Thiel, Steffen, & Mueller, Christian. (2023). Diagnostic and prognostic value of H-ficolin for functionally relevant coronary artery disease. Clinica Chimica Acta, 551. https://doi.org/10.1016/j.cca.2023.117582

Gross, Sebastian, Becker, Christoph, Beck, Katharina, Memma, Valentina, Gaab, Jens, Schütz, Philipp, Leuppi, Jörg D., Schaefert, Rainer, Langewitz, Wolf, Trendelenburg, Marten, Breidthardt, Tobias, Eckstein, Jens, Osthoff, Michael, Bassetti, Stefano, & Hunziker, Sabina. (2023). Occurrence of sensitive topics during ward round: An ancillary analysis of the BEDSIDE-OUTSIDE trial. BMJ Open, 13(9). https://doi.org/10.1136/bmjopen-2023-073584

Breillat P, Jachiet M, Ditchi Y, Lenormand C, Costedoat-Chalumeau N, Mathian A, Moguelet P, Duriez P, Trendelenburg M, Huynh-Do U, Chizzolini C, Beuvon C, Roy-Peaud F, Bouaziz JD, Barbaud A, Francès C, Mékinian A, Fain O, Amoura Z, et al. (2023). Cutaneous vasculitis occurring in the setting of systemic lupus erythematosus: a multicentre cohort study. Rheumatology (United Kingdom), 62(6), 2189–2196. https://doi.org/10.1093/rheumatology/keac566

Isayeva, Anna, Potlukova,Eliska, Rumora,Klara, Kurun, Atakan, Leibfarth, Jan-Philipp, Schafer, Ibrahim, Zellweger, Michael, Trendelenburg, Marten, Thiel, Steffen, & Mueller, Christian. (2023). Diagnostic and Prognostic Value of H-ficolin and Mannose-Binding Lectin for Functionally Relevant Coronary Artery Disease. Swiss Medicalf Weekly, 153, 110S–110S.

Kleer, Jessica S., Skattum, Lillemor, Dubler, Denise, Fischer, Ingeborg, Zgraggen, Armin, Mundwiler, Esther, Kim, Min Jeong, & Trendelenburg, Marten. (2023). Complement C1s deficiency in a male Caucasian patient with systemic lupus erythematosus: a case report. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1257525

Schulz, Kristina, Donat, Claudia, Punjabi, Mukesh, Glatz, Katharina, Kaufmann, Beat, & Trendelenburg, Marten. (2023). Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1265387

Schulz, Kristina, Donat, Claudia, Punjabi, Mukesh, Glatz, Katharina, Kaufmann, Beat, & Trendelenburg, Marten. (2023). Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery [Journal-article]. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1265387

Urwyler, Pascal, Leimbacher, Marina, Charitos, Panteleimon, Moser, Stephan, Heijnen, Ingmar A. F. M., Trendelenburg, Marten, Thoma, Reto, Sumer, Johannes, Camacho-Ortiz, Adrián, Bacci, Marcelo R., Huber, Lars C., Stüssi-Helbling, Melina, Albrich, Werner C., Sendi, Parham, & Osthoff, Michael. (2023). Recombinant C1 inhibitor in the prevention of severe COVID-19: a randomized, open-label, multi-center phase IIa trial. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1255292

Urwyler, Pascal, Moser, Stephan, Trendelenburg, Marten, Sendi, Parham, & Osthoff, Michael. (2022). Targeting thromboinflammation in COVID-19 – A narrative review of the potential of C1 inhibitor to prevent disease progression. Molecular Immunology, 150, 99–113. https://doi.org/10.1016/j.molimm.2022.08.008

Bruni F, Charitos P, Lampart M, Moser S, Siegemund M, Bingisser R, Osswald S, Bassetti S, Twerenbold R, Trendelenburg M, Rentsch KM, & Osthoff M. (2022). Complement and endothelial cell activation in COVID-19 patients compared to controls with suspected SARS-CoV-2 infection: A prospective cohort study. Frontiers in Immunology, 13, 941742. https://doi.org/10.3389/fimmu.2022.941742

Schulz K., & Trendelenburg M. (2022). C1q as a target molecule to treat human disease: What do mouse studies teach us? Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.958273

Capoferri G, Daikeler T, Mühleisen B, Trendelenburg M, & Müller S. (2022). Cutaneous leukocytoclastic vasculitis secondary to COVID-19 infection leading to extensive skin necrosis. Clinics in Dermatology, 40(4), 397–401. https://doi.org/10.1016/j.clindermatol.2022.02.013

Costa A.E., Bernasconi N.S., Trendelenburg M., & Schunemann M.J. (2022). Severe myopathy complicating multisystem inflammatory syndrome in adults (MIS-A) in a young man. BMJ Case Reports, 15(7). https://doi.org/10.1136/bcr-2022-250054

Huebner, Simona Tabea, Henny, Simona, Giezendanner, Stéphanie, Brack, Thomas, Brutsche, Martin, Chhajed, Prashant, Clarenbach, Christian, Dieterle, Thomas, Egli, Adrian, Frey, Martin, Heijnen, Ingmar, Irani, Sarosh, Sievi, Noriane Andrina, Thurnheer, Robert, Trendelenburg, Marten, Kohler, Malcolm, Leuppi-Taegtmeyer, Anne Barbara, & Leuppi, Joerg Daniel. (2022). Prediction of Acute COPD Exacerbation in the Swiss Multicenter COPD Cohort Study (TOPDOCS) by Clinical Parameters, Medication Use, and Immunological Biomarkers. Respiration, 101(5), 441–454. https://doi.org/10.1159/000520196

Gross S., Beck K., Becker C., Gamp M., Mueller J., Loretz N., Amacher S.A., Bohren C., Gaab J., Schuetz P., Mueller B., Fux C.A., Leuppi J.D., Schaefert R., Langewitz W., Trendelenburg M., Breidthardt T., Eckstein J., Osthoff M., et al. (2022). Perception of physicians and nursing staff members regarding outside versus bedside ward rounds: Ancillary analysis of the randomised BEDSIDE-OUTSIDE trial. Swiss Medical Weekly, 152(3-4). https://doi.org/10.4414/smw.2022.w30112

Kleer JS, Rabatscher PA, Weiss J., Leonardi J, Vogt SB, Kieninger-Grafitsch A., Chizzolini C., Huynh-Do U., Ribi C., & Trendelenburg M. (2022). Epitope-Specific Anti-C1q Autoantibodies in Systemic Lupus Erythematosus. Frontiers in Immunology, 12, 761395. https://doi.org/10.3389/fimmu.2021.761395

Chasset F., Mathian A., Dorgham K., Ribi C., Trendelenburg M., Huynh-Do U., Roux-Lombard P., Courvoisier D.S., Amoura Z., Gorochov G., & Chizzolini C. (2022). Serum interferon-α levels and IFN type I-stimulated genes score perform equally to assess systemic lupus erythematosus disease activity. Annals of the Rheumatic Diseases, 81(6), 901–903. https://doi.org/10.1136/annrheumdis-2021-221835

Potlukova, Eliska, Seelmann,Sonja, Meienberg,Andrea, Kassi,Elianne, von Rotz,Matthias, Wilde,Michael, Voigt,Gabriele, Thies,Katharina, Schünemann,Max, Popescu,Codruta, Nehring,Josephine, Müller,Olivia, Boss,Oliver, Etienne,Samuel, Rohacek,Martin, Reichenstein,David, Krähenbühl,Martin, Trendelenburg,Marten, & Bassetti,Stefano. (2022). First-year medical students at the patient bed – early clinical exposure through a project-based learning tool in internal medicine. AMEE 2022 – Lyon, France, Abstract ID: 3679.

Rabatscher P.A., & Trendelenburg M. (2022). Anti-C1q autoantibodies from systemic lupus erythematosus patients enhance CD40–CD154-mediated inflammation in peripheral blood mononuclear cells in vitro. Clinical and Translational Immunology, 11(8). https://doi.org/10.1002/cti2.1408

Seelmann,Sonja, Meienberg,Andrea, Kassi,Elianne, von Rotz,Matthias, Wilde,Michael, Voigt, Gabriele, Thies,Katharina, Schünemann,Max, Popescu,Codruta, Nehring,Josephine, Müller,Olivia, Boss,Oliver, Etienne,Samuel, Rohacek,Martin, Reichenstein,David, Krähenbühl,Martin, Bassetti,Stefano, Trendelenburg,Marten, & Potlukova,Eliska. (2022, January 1). First-year medical students at the patient bed – early clinical exposure through a project-based learning tool in internal medicine. SGAIM Frühjahrskongress.

Urwyler, Pascal, Charitos, Panteleimon, Moser, Stephan, Heijnen, Ingmar A. F. M., Trendelenburg, Marten, Thoma, Reto, Sumer, Johannes, Camacho-Ortiz, Adrián, Bacci, Marcelo R., Huber, Lars C., Stüssi-Helbling, Melina, Albrich, Werner C., Sendi, Parham, & Osthoff, Michael. (2021). Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of severe SARS-CoV-2 infection in hospitalized patients with COVID-19: A structured summary of a study protocol for a randomized, parallel-group, open-label, multi-center pilot trial (PROTECT-COVID-19). Trials, 22(1). https://doi.org/10.1186/s13063-020-04976-x

Vogt S, Leuppi JD, Schuetz P, Mueller B, Volken C, Dräger S, Trendelenburg M, Rutishauser J, Rutishauser J, & Osthoff M. (2021). Association of mannose-binding lectin, ficolin-2 and immunoglobulin concentrations with future exacerbations in patients with chronic obstructive pulmonary disease: secondary analysis of the randomized controlled REDUCE trial. Respiratory Research, 22(1), 227. https://doi.org/10.1186/s12931-021-01822-9

Charitos P., Heijnen IAFM, Egli A, Bassetti S., Trendelenburg M., & Osthoff M. (2021). Functional Activity of the Complement System in Hospitalized COVID-19 Patients: A Prospective Cohort Study. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.765330

Becker C, Gamp M., Schuetz P., Beck K., Vincent A, Hochstrasser S., Metzger K., Widmer M., Thommen E, Mueller B, Fux CA, Leuppi JD, Schaefert R, Langewitz W., Trendelenburg M., Breidthardt T, Eckstein J, Osthoff M, Bassetti S., & Hunziker S. (2021). Effect of bedside compared with outside the room patient case presentation on patients’ knowledge about their medical care: A randomized, controlled, multicenter trial. Annals of Internal Medicine, 174(9), 1282–1292. https://doi.org/10.7326/m21-0909

Kiener S., Ribi C., Keller I., Chizzolini C., Trendelenburg M., Huynh-Do U., von Kempis J., & Leeb T. (2021). Variants affecting the C-terminal tail of UNC93B1 are not a common risk factor for systemic lupus erythematosus. Genes, 12(8). https://doi.org/10.3390/genes12081268

Mihailovic, J., Ribi, C., Chizzolini, C., Trendelenburg, M., Von Kempis, J., Huynh-Do, U., & Dahdal, S. (2021). Worse Cardiovascular and Renal Outcome in Male SLE Patients: First Gender Study From the Swiss SLE Cohort Study [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-645732/v1

Csorba K., Schirmbeck L., Dubler D., & Trendelenburg M. (2021). Anti-C1q Autoantibodies: Standard Quantification and Innovative ELISA. In Methods in Molecular Biology (Vol. 2227, pp. 107–114). Humana Press Inc. https://doi.org/10.1007/978-1-0716-1016-9_10

Trendelenburg M. (2021). Autoantibodies against complement component C1q in systemic lupus erythematosus. Clinical and Translational Immunology, 10(4). https://doi.org/10.1002/cti2.1279

Kieninger-Gräfitsch A, Vogt S, Ribi C, Dubler D, Chizzolini C, Huynh-Do U, Osthoff M, & Trendelenburg M. (2020). No association of complement mannose-binding lectin deficiency with cardiovascular disease in patients with Systemic Lupus Erythematosus. Scientific Reports, 10(1), 3693. https://doi.org/10.1038/s41598-020-60523-3

Chasset F, Ribi C, Trendelenburg M, Huynh-Do U, Roux-Lombard P, Courvoisier DS, Chizzolini C, & Swiss SLE Cohort Study (SSCS. (2020). Identification of highly active systemic lupus erythematosus by combined type I interferon and neutrophil gene scores vs classical serologic markers. Rheumatology (United Kingdom), 59(11), 3468–3478. https://doi.org/10.1093/rheumatology/keaa167

Strasser DS, Froidevaux S, Sippel V, Gerossier E, Grieder U, Pierlot GM, Kieninger-Graefitsch A, Vezzali E, Stalder AK, Renault B, Ryge J, Hart A, Mentzel U, Groenen PMA, Keller MP, Trendelenburg M, Martinic MM, & Murphy MJ. (2020). Preclinical to clinical translation of cenerimod, a novel S1P 1 receptor modulator, in systemic lupus erythematosus. RMD Open, 6(2). https://doi.org/10.1136/rmdopen-2020-001261

Urwyler, Pascal, Moser, Stephan, Charitos, Panteleimon, Heijnen, Ingmar A. F. M., Rudin, Melanie, Sommer, Gregor, Giannetti, Bruno M., Bassetti, Stefano, Sendi, Parham, Trendelenburg, Marten, & Osthoff, Michael. (2020). Treatment of COVID-19 With Conestat Alfa, a Regulator of the Complement, Contact Activation and Kallikrein-Kinin System. Frontiers in Immunology, 11. https://doi.org/10.3389/fimmu.2020.02072

Donat C, Kölm R, Csorba K, Tuncer E, Tsakiris DA, & Trendelenburg M. (2020). Complement C1q Enhances Primary Hemostasis. Frontiers in Immunology, 11, 1522. https://doi.org/10.3389/fimmu.2020.01522

Sarcevic J, Cavelti-Weder C, Berger CT, & Trendelenburg M. (2020). Case Report—Secondary Antibody Deficiency Due to Endogenous Hypercortisolism [Frontiers Media S.A.]. Frontiers in Immunology, 11, 1435. https://doi.org/10.3389/fimmu.2020.01435

Panagiotou A, Trendelenburg M, Heijnen IAFM, Moser S, Bonati LH, Breidthardt T, Fahrni G, Kaiser C, Jeger R, & Osthoff M. (2020). A Randomized Trial of Recombinant Human C1-Esterase-Inhibitor in the Prevention of Contrast-Induced Kidney Injury. JACC: Cardiovascular Interventions, 13(7), 833–842. https://doi.org/10.1016/j.jcin.2019.11.021

Nigolian H, Ribi C, Courvoisier DS, Pagano S, Alvarez M, Trendelenburg M, Huynh-Do U, Vuilleumier N, Dayer JM, Chizzolini C, & Roux-Lombard P. (2020). Anti-apolipoprotein A-1 autoantibodies correlate with disease activity in systemic lupus erythematosus. Rheumatology (United Kingdom), 59(3), 534–544. https://doi.org/10.1093/rheumatology/kez306

Sarcevic, Jelena, Cavelti-Weder, Claudia, Berger, T. Christoph, & Trendelenburg, Marten. (2020). Secondary Antibody Deficiency Due to Endogenous Hypercortisolism. Frontiers in Immunology, 11, 1435. https://doi.org/10.3389/fimmu.2020.01435

Vogt, Severin, Trendelenburg, Marten, Tamm, Michael, Stolz , Daiana, Hostettler, Katrin Esther, & Osthoff, Michael. (2020). Local and Systemic Concentration of Pattern Recognition Receptors of the Lectin Pathway of Complement in a Cohort of Patients With Interstitial Lung Diseases. Frontiers in Immunology, 11, 562564. https://doi.org/10.3389/fimmu.2020.562564

von Rotz, M., Grimm, K., Arranto, C., Burkhalter, F., Erb, S., Trendelenburg, M., & Breidthardt, T. (2019). Aussergewöhnliche Ursache von Rückenschmerzen [Journal-article]. Swiss Medical Forum ‒ Schweizerisches Medizin-Forum. https://doi.org/10.4414/smf.2019.08340

Donat C, Thanei S, & Trendelenburg M. (2019). Binding of von Willebrand Factor to Complement C1q Decreases the Phagocytosis of Cholesterol Crystals and Subsequent IL-1 Secretion in Macrophages. Frontiers in Immunology, 10, 2712. https://doi.org/10.3389/fimmu.2019.02712

Friebus-Kardash J, Trendelenburg M, Eisenberger U, Ribi C, Chizzolini C, Huynh-Do U, Lang KS, Wilde B, Kribben A, Witzke O, Dolff S, & Hardt C. (2019). Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis. BMC Nephrology, 20(1), 430. https://doi.org/10.1186/s12882-019-1623-4

Csorba K, Schirmbeck LA, Tuncer E, Ribi C, Roux-Lombard P, Chizzolini C, Huynh-Do U, Vanhecke D, & Trendelenburg M. (2019). Anti-C1q Antibodies as Occurring in Systemic Lupus Erythematosus Could Be Induced by an Epstein-Barr Virus-Derived Antigenic Site. Frontiers in Immunology, 10, 2619. https://doi.org/10.3389/fimmu.2019.02619

Troldborg A, Steffensen R, Trendelenburg M, Hauser T, Winther KG, Hansen AG, Stengaard-Pedersen K, Voss A, & Thiel S. (2019). Ficolin-3 Deficiency Is Associated with Disease and an Increased Risk of Systemic Lupus Erythematosus. Journal of Clinical Immunology, 39(4), 421–429. https://doi.org/10.1007/s10875-019-00627-2

Pröbstel AK, Thanei M, Erni B, Lecourt AC, Branco L, André R, Roux-Lombard P, Koenig KF, Huynh-Do U, Ribi C, Chizzolini C, Kappos L, Trendelenburg M, Derfuss T, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2019). Association of antibodies against myelin and neuronal antigens with neuroinflammation in systemic lupus erythematosus. Rheumatology (United Kingdom), 58(5), 908–913. https://doi.org/10.1093/rheumatology/key282

Osthoff M, Jaeger VK, Heijnen IAFM, Trendelenburg M, Jordan S, Distler O, & Walker U.A. (2019). Role of lectin pathway complement proteins and genetic variants in organ damage and disease severity of systemic sclerosis: A cross-sectional study. Arthritis Research and Therapy, 21(1). https://doi.org/10.1186/s13075-019-1859-1

Nehring J, Schirmbeck LA, Friebus-Kardash J, Dubler D, Huynh-Do U, Chizzolini C, Ribi C, & Trendelenburg M. (2018). Autoantibodies against Albumin in patients with systemic lupus erythematosus. Frontiers in Immunology, 9(OCT), 2090. https://doi.org/10.3389/fimmu.2018.02090

Burkard T, Trendelenburg M, Daikeler T, Hess C, Bremerich J, Haaf P, Buser P, & Zellweger MJ. (2018). The heart in systemic lupus erythematosus – A comprehensive approach by cardiovascular magnetic resonance tomography. PLoS ONE, 13(10), e0202105. https://doi.org/10.1371/journal.pone.0202105

Marchetti T, Ribi C, Perneger T, Trendelenburg M, Huynh-Do U, de Moerloose P, & Chizzolini C. (2018). Prevalence, persistence and clinical correlations of classic and novel antiphospholipid antibodies in systemic lupus erythematosus. Rheumatology (United Kingdom), 57(8), 1350–1357. https://doi.org/10.1093/rheumatology/key095

Troldborg A, Thiel S, Trendelenburg M, Friebus-Kardash J, Nehring J, Steffensen R, Hansen SWK, Laska MJ, Deleuran B, Jensenius JC, Voss A, & Stengaard-Pedersen K. (2018). The lectin pathway of complement activation in patients with systemic lupus erythematosus. Journal of Rheumatology, 45(8), 1136–1144. https://doi.org/10.3899/jrheum.171033

Panagiotou A, Trendelenburg M, & Osthoff M. (2018). The Lectin pathway of complement in myocardial ischemia/reperfusion injury-review of its significance and the potential impact of therapeutic interference by C1 esterase inhibitor. Frontiers in Immunology, 9(MAY), 1151. https://doi.org/10.3389/fimmu.2018.01151

Dahdal S, Devetzis V, Chalikias G, Tziakas D, Chizzolini C, Ribi C, Trendelenburg M, Eisenberger U, Hauser T, Pasch A, Huynh-Do U, Arampatzis S, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2018). Serum calcification propensity is independently associated with disease activity in systemic lupus erythematosus. PLoS ONE, 13(1), e0188695. https://doi.org/10.1371/journal.pone.0188695

Friebus-Kardash J, Branco L, Ribi C, Chizzolini C, Huynh-Do U, Dubler D, Roux-Lombard P, Dolff S, Kribben A, Eisenberger U, & Trendelenburg M. (2018). Immune complexes containing serum B-cell activating factor and immunoglobulin G correlate with disease activity in systemic lupus erythematosus. Nephrology Dialysis Transplantation, 33(1), 54–64. https://doi.org/10.1093/ndt/gfx220

Trendelenburg, Marten, Stallone, Fabio, Pershyna, Kateryna, Eisenhut, Timo, Twerenbold, Raphael, Wildi, Karin, Dubler, Denise, Schirmbeck, Lucia, Puelacher, Christian, Rubini Gimenez, Maria, Sabti, Zaid, Osswald, Luca, Breidthardt, Tobias, & Müller, Christian. (2018). Complement activation products in acute heart failure: Potential role in pathophysiology, responses to treatment and impacts on long-term survival. European heart journal. Acute cardiovascular care, 7(4), 348–357. https://doi.org/10.1177/2048872617694674

Thanei S, Theron M, Silva AP, Reis B, Branco L, Schirmbeck L, Kolb FA, Haap W, Schindler T, & Trendelenburg M. (2017). Cathepsin S inhibition suppresses autoimmune-triggered inflammatory responses in macrophages. Biochemical Pharmacology, 146, 151–164. https://doi.org/10.1016/j.bcp.2017.10.001

Osthoff M, Walder B, Delhumeau C, Trendelenburg M, & Turck N. (2017). Association of Lectin Pathway Protein Levels and Genetic Variants Early after Injury with Outcomes after Severe Traumatic Brain Injury: A Prospective Cohort Study. Journal of Neurotrauma, 34(17), 2560–2566. https://doi.org/10.1089/neu.2016.4941

Huber, Xaver, Degen, Lukas, Muenst, Simone, & Trendelenburg, Marten. (2017). Primary intestinal lymphangiectasia in an elderly female patient: A case report on a rare cause of secondary immunodeficiency. Medicine, 96(31), e7729. https://doi.org/10.1097/md.0000000000007729

Kofler T, Yueksel F, Dirnhofer S, Donath MY, & Trendelenburg M. (2017). [Abdominal pain and hypertension in a 55-year-old male patient]. Der Internist, 58(4), 397–401. https://doi.org/10.1007/s00108-016-0170-3

Chaigne B, Chizzolini C, Perneger T, Trendelenburg M, Huynh-Do U, Dayer E, Stoll T, von Kempis J, Ribi C, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2017). Impact of disease activity on health-related quality of life in systemic lupus erythematosus - a cross-sectional analysis of the Swiss Systemic Lupus Erythematosus Cohort Study (SSCS). BMC Immunology, 18(1), 17. https://doi.org/10.1186/s12865-017-0200-5

Thanei S, & Trendelenburg M. (2017). Anti-C1q autoantibodies from patients with systemic lupus erythematosus induce C1q production by macrophages. Journal of Leukocyte Biology, 101(2), 481–491. https://doi.org/10.1189/jlb.3A1215-535R

Kolm, R., Schaller, M., Roumenina, L. T., Niemiec, I., Kremer Hovinga, J. A., Khanicheh, E., Kaufmann, B. A., Hopfer, H., & Trendelenburg, M. (2016). Von Willebrand Factor Interacts with Surface-Bound C1q and Induces Platelet Rolling. J Immunol, 197(9), 3669–3679. https://doi.org/10.4049/jimmunol.1501876

Osthoff, Michael, Osthoff, Michael, Wojtowicz, Agnieszka, Tissot, Frederic, Jørgensen, Clara, Thiel, Steffen, Zimmerli, Stephan, Marchetti, Oscar, Khanna, Nina, Bochud, Pierre-Yves, Trendelenburg, Marten, Fungal Infection Network of Switzerland, & Fungal Infection Network of Switzerland Funginos. (2016). Association of lectin pathway proteins with intra-abdominal Candida infection in high-risk surgical intensive-care unit patients. A prospective cohort study within the fungal infection network of Switzerland. The Journal of Infection, 72(3), 85–377. https://doi.org/10.1016/j.jinf.2015.12.011

Thanei, S., & Trendelenburg, M. (2016). Anti-C1q Autoantibodies from Systemic Lupus Erythematosus Patients Induce a Proinflammatory Phenotype in Macrophages. J Immunol, 196(5), 74–2063. https://doi.org/10.4049/jimmunol.1501659

Vitkova, H., Jiskra, J., Springer, D., Limanova, Z., Telicka, Z., Bartakova, J., Trendelenburg, M., & Potlukova, E. (2016). Anti-C1q autoantibodies are linked to autoimmune thyroid disorders in pregnant women. Clin Exp Immunol, 186(1), 7–10. https://doi.org/10.1111/cei.12813

Stegert M, Bock M, & Trendelenburg M. (2015). Clinical presentation of human C1q deficiency: How much of a lupus? Molecular Immunology, 67(1), 3–11. https://doi.org/10.1016/j.molimm.2015.03.007

Bock, Merete, Heijnen, Ingmar, & Trendelenburg, Marten. (2015). Anti-C1q antibodies as a follow-up marker in SLE patients. PLoS ONE, 10(4), e0123572. https://doi.org/10.1371/journal.pone.0123572

Koenig, K. F., Ribi, C., Radosavac, M., Zulewski, H., Trendelenburg, Marten, & Swiss, S. L. E. cohort study. (2015). Prevalence of vascular disease in systemic lupus erythematosus compared with type-1 diabetes mellitus: a cross-sectional study of two cohorts. Lupus, 24(1), 58–65. https://doi.org/10.1177/0961203314550223

Mandal, Jyotshna, Malla, Bijaya, Steffensen, Rudi, Costa, Luigi, Egli, Adrian, Trendelenburg, Marten, Blasi, Francesco, Kostikas, Kostantinos, Welte, Tobias, Torres, Antoni, Louis, Renaud, Boersma, Wim, Milenkovic, Branislava, Aerts, Joachim, Rohde, Gernot G., Lacoma, Alicia, Rentsch, Katharina, Roth, Michael, Tamm, Michael, & Stolz, Daiana. (2015). Mannose-binding lectin protein and its association to clinical outcomes in COPD: a longitudinal study. Respir Res, 16, 150. https://doi.org/10.1186/s12931-015-0306-3

Pesickova, Satu Sinikka, Rysava, Romana, Lenicek, Martin, Vitek, Libor, Potlukova, Eliska, Hruskova, Zdenka, Jancova, Eva, Honsova, Eva, Zavada, Jakub, Trendelenburg, Marten, & Tesar, Vladimir. (2015). Prognostic value of anti-CRP antibodies in lupus nephritis in long-term follow-up. Arthritis Research & Therapy, 17, 371. https://doi.org/10.1186/s13075-015-0879-8

Thanei, Sophia, Vanhecke, Dominique, & Trendelenburg, Marten. (2015). Anti-C1q autoantibodies from systemic lupus erythematosus patients activate the complement system via both the classical and lectin pathways. Clinical Immunology, 160(2), 7–180. https://doi.org/10.1016/j.clim.2015.06.014

Ribi C, Trendelenburg M, Gayet-Ageron A, Cohen C, Dayer E, Eisenberger U, Hauser T, Hunziker T, Leimgruber A, Lindner G, Koenig K, Otto P, Spertini F, Stoll T, Von Kempis J, Chizzolini C, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2014). The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - Cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland. Swiss Medical Weekly, 144, w13990. https://doi.org/10.4414/smw.2014.13990

Schifferli J.A., & Trendelenburg M. (2014). Cryoglobulinemia and chronic HCV infection: An evolving story. In HCV Infection and Cryoglobulinemia (pp. 79–83). Springer-Verlag Italia s.r.l. https://doi.org/10.1007/978-88-470-1705-4_9

Nytrova, Petra, Potlukova, Eliska, Kemlink, David, Woodhall, Mark, Horakova, Dana, Waters, Patrick, Havrdova, Eva, Zivorova, Dana, Vincent, Angela, & Trendelenburg, Marten. (2014). Complement activation in patients with neuromyelitis optica. Journal of Neuroimmunology, 274(1-2), 91–185. https://doi.org/10.1016/j.jneuroim.2014.07.001

Potlukova E, Freiberger T, Limanova Z, Jiskra J, Telicka Z, Bartakova J, Springer D, Vitkova H, & Trendelenburg M. (2013). Association between low levels of mannan-binding lectin and markers of autoimmune thyroid disease in pregnancy. PLoS ONE, 8(12), e81755. https://doi.org/10.1371/journal.pone.0081755

Osthoff M, & Trendelenburg M. (2013). Impact of mannose-binding lectin deficiency on radiocontrast-induced renal dysfunction. BioMed Research International, 2013(1), 962695. https://doi.org/10.1155/2013/962695

Scharein P, & Trendelenburg M. (2013). Critical incidents in a tertiary care clinic for internal medicine. BMC Research Notes, 6(1), 276. https://doi.org/10.1186/1756-0500-6-276

Trendelenburg, M., & Ribi, C. (2013). Systemischer Lupus Erythematodes – die «Swiss SLE Cohort Study (SSCS)» [Journal-article]. Swiss Medical Forum ‒ Schweizerisches Medizin-Forum, 13(22). https://doi.org/10.4414/smf.2013.01532

Egli, A., Schafer, J., Osthoff, M., Thiel, S., Mikkelsen, C., Rauch, A., Hirsch, H. H., Bucher, H. C., Young, J., Jensenius, J. C., Battegay, M., & Trendelenburg, M. (2013). Low levels of mannan-binding lectin or ficolins are not associated with an increased risk of cytomegalovirus disease in HIV-infected patients. PLoS ONE, 8(1), e51983. https://doi.org/10.1371/journal.pone.0051983

Vanhecke D., Roumenina, Lubka T., Wan H., Osthoff, Michael, Schaller M., & Trendelenburg M. (2012). Identification of a major linear C1q epitope allows detection of systemic lupus erythematosus anti-C1q antibodies by a specific peptide-based enzyme-linked immunosorbent assay. Arthritis and Rheumatism, 64(11), 3706–3714. https://doi.org/10.1002/art.34605

Osthoff M, Piezzi V, Klima T, Christ A, Marana I, Hartwiger S, Breidthardt T, Marenzi G, Trendelenburg M, & Mueller C. (2012). Impact of mannose-binding lectin deficiency on radiocontrast-induced renal dysfunction: A post-hoc analysis of a multicenter randomized controlled trial. BMC Nephrology, 13(1), 99. https://doi.org/10.1186/1471-2369-13-99

Trendelenburg M. (2012). The complement system in cryoglobulinemia. In HCV Infection and Cryoglobulinemia (Vol. 9788847017054, pp. 85–89). Springer-Verlag Italia s.r.l. https://doi.org/10.1007/978-88-470-1705-4_10

Hirt-Minkowski, P., Trendelenburg, M., Groschl, I., Fischer, A., Heijnen, I., & Schifferli, J. A. (2012). A trial of complement inhibition in a patient with cryoglobulin-induced glomerulonephritis. Case Reports in Nephrology and Urology, 2(1), 38–45. https://doi.org/10.1159/000339403

Koenig, Katrin Franzika, Groeschl, Isabel, Pesickova, Satu Sinikka, Tesar, Vladimir, Eisenberger, Ute, & Trendelenburg, Marten. (2012). Serum cytokine profile in patients with active lupus nephritis. Cytokine, 60(2), 6–410. https://doi.org/10.1016/j.cyto.2012.07.004

Koenig, K. F., Potlukova, E., Müller, B., Christ-Crain, M., & Trendelenburg, M. (2012). MBL serum levels in patients with sepsis correlate with thyroid function but not with outcome. Clinical Immunology, 144(1), 2–80. https://doi.org/10.1016/j.clim.2012.05.002

Trendelenburg M. (2012). Anti-C1q antibodies as a diagnostic marker of proliferative lupus nephritis: Comment on the article by Katsumata et al (Patent No. 1). Arthritis and Rheumatism, 64(1), Article 1. https://doi.org/10.1002/art.33384

Osthoff M, Katan M., Fluri F., Schuetz P, Bingisser R, Kappos L, Steck AJ, Engelter ST, Mueller B, Christ-Crain M, & Trendelenburg M. (2011). Mannose-binding lectin deficiency is associated with smaller infarction size and favorable outcome in ischemic stroke patients. PLoS ONE, 6(6). https://doi.org/10.1371/journal.pone.0021338

Benz, Nadja, Daikeler, Thomas, Frank, Stephan, Mehling, Matthias, Tyndall, Alan, & Trendelenburg, Marten. (2011). Three cases of primary small vessel vasculitis of the skeletal muscle-an own entity. BMJ Case Reports, 2011, Nov 8. https://doi.org/10.1136/bcr.08.2011.4631

Bigler, Cornelia, Hopfer, Helmut, Danner, Doris, Schaller, Monica, Mihatsch, Michael J, & Trendelenburg, Marten. (2011). Anti-C1q autoantibodies do not correlate with the occurrence or severity of experimental lupus nephritis. Nephrology, Dialysis, Transplantation, 26(4), 8–1220. https://doi.org/10.1093/ndt/gfq558

Osthoff, Michael, Trendelenburg, George, Eisen, Damon P, & Trendelenburg, Marten. (2011). Mannose-binding lectin - the forgotten molecule? Nature Medicine, 17(12), 1547–8; author reply 1548. https://doi.org/10.1038/nm.2588