[FG] Hutter Gregor
Head of Research Unit
Prof. Dr.Gregor Hutter
Research Group Gregor Hutter
Research Focus
Oncology & Hematology
Area of Research
We are working on novel immunotherapies for malignant brain tumors, in particular glioblastoma. On the one hand, we have developed innovative preclinical models to modulate the innate immune system in the tumor, on the other hand, we would like to further develop these therapies translationally in first-in-human clinical trials.
Approved Research Projects
- Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery. Science Advances, 2022 – DOI: 10.1126/sciadv.abn9440
- Microglia-Centered Combinatorial Strategies Against Glioblastoma. Frontiers Immunology, 2020 – https://doi.org/10.3389/fimmu.2020.571951
- Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma PNAS, 2019 – https://doi.org/10.1073/pnas.1721434116
Collaborations
National Collaborations
- DBM Collaborations: Prof. Heinz Läubli, Prof. Alfred Zippelius, Prof. Bentires-Alj, Prof. Guzman, Prof. L. Jeker, PD Dr. Matthias Matter, Prof. Tzankov, Prof. Ivan Martin, Prof. AK Proebstel, Prof. Kuhle
- UZH: Dr. Tobias Weiss, Dr. Johannes vom Berg
- Incephalo AG
- Idorsia Pharmaceuticals
International Collaborations
- Prof. Christian Schuerch, D
- Prof. Gary Nolan, USA