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[FG] Busche Marc Aurel

Publications

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Dietsche, Sebastian et al. (2026) ‘Assessing DSM-5 criteria of somatic symptom disorder in medically hospitalized inpatients: A cross-sectional analysis’, General Hospital Psychiatry. 01.01.2026, 99, pp. 6–15. Available at: https://doi.org/10.1016/j.genhosppsych.2025.12.023.

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Fabi, Adriano et al. (2026) ‘Neurolymphatic clearance in neurodegenerative disease: Emerging mechanisms and potential translational strategies’, JPRAS Open, 48, pp. 438–449. Available at: https://doi.org/10.1016/j.jpra.2025.12.013.

Semenkova, Anna et al. (2025) ‘Reference-Group Adjusted Behavioural Dysfunction Questionnaire Score Discriminates Highly Behavioural-Variant Frontotemporal Dementia From Major Depressive Disorder and Alzheimer’s Disease Dementia’, European Journal of Neurology, 32(11). Available at: https://doi.org/10.1111/ene.70424.

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Jafree, D.J. et al. (2025) ‘Organ-specific features of human kidney lymphatics are disrupted in chronic transplant rejection’, Journal of Clinical Investigation, 135(18). Available at: https://doi.org/10.1172/jci168962.

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Cerami, Chiara et al. (2025) ‘Understanding barriers and optimizing socio‐cognitive assessment in the diagnosis of neurocognitive disorders’, Journal of Neuropsychology. 14.05.2025, 19(3), pp. 603–618. Available at: https://doi.org/10.1111/jnp.12431.

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Papanikolaou, A. et al. (2025) ‘Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer’s disease models in vivo’, 113(14), pp. 2265–2279.e7. Available at: https://doi.org/10.1016/j.neuron.2025.04.010.

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Harris, S.S. et al. (2025) ‘Alzheimer’s disease patient-derived high-molecular-weight tau impairs bursting in hippocampal neurons’, 188(14), pp. 3775–3788.e21. Available at: https://doi.org/10.1016/j.cell.2025.04.006.

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Harris, S.S. et al. (2025) ‘The amyloid precursor family of proteins in excitatory neurons are essential for regulating cortico-hippocampal circuit dynamics in vivo’, 44(6). Available at: https://doi.org/10.1016/j.celrep.2025.115801.

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Felbecker, Ansgar et al. (2025) ‘Anti-Amyloid Monoclonal Antibodies for the Treatment of Alzheimer Disease: Intersocietal Recommendations for Their Appropriate Use in Switzerland’, Neurodegenerative Diseases. 14.04.2025, 25(3), pp. 114–125. Available at: https://doi.org/10.1159/000545799.

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Dodich, Alessandra et al. (2025) ‘International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative’, Alzheimer’s Research and Therapy. 06.12.2025, 18(1). Available at: https://doi.org/10.1186/s13195-025-01908-2.

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Zott, B. et al. (2024) ‘β-amyloid monomer scavenging by an anticalin protein prevents neuronal hyperactivity in mouse models of Alzheimer’s Disease’, 15(1). Available at: https://doi.org/10.1038/s41467-024-50153-y.

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Chen, Z. et al. (2024) ‘Interpreting Sleep Activity Through Neural Contrastive Learning’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2024.09.25.615100.

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Rajani, R.M. et al. (2024) ‘Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s Disease’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2024.06.21.600003.

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Milioto, C. et al. (2024) ‘PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons’, 27(4), pp. 643–655. Available at: https://doi.org/10.1038/s41593-024-01589-4.

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Milioto, C. et al. (2023) ‘PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2023.07.17.549331.

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Jafree, D.J. et al. (2022) ‘Three-dimensional imaging and single-cell transcriptomics of the human kidney implicate perturbation of lymphatics in alloimmunity’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2022.10.28.514222.

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Ong-Pålsson, E. et al. (2022) ‘The β-Secretase Substrate Seizure 6–Like Protein (SEZ6L) Controls Motor Functions in Mice’, 59(2), pp. 1183–1198. Available at: https://doi.org/10.1007/s12035-021-02660-y.

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Mensch, M. et al. (2021) ‘Aη-α and Aη-β peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo’, 13(1). Available at: https://doi.org/10.1186/s13195-021-00860-1.

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Maestú, F. et al. (2021) ‘Neuronal excitation/inhibition imbalance: core element of a translational perspective on Alzheimer pathophysiology’, 69. Available at: https://doi.org/10.1016/j.arr.2021.101372.

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Harris, S.S. et al. (2021) ‘The Reciprocal Interaction Between Sleep and Alzheimer’s Disease’, in Advances in Experimental Medicine and Biology. Springer (Advances in Experimental Medicine and Biology), pp. 169–188. Available at: https://doi.org/10.1007/978-3-030-81147-1_10.

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Busche, M.A. and Hyman, B.T. (2020) ‘Synergy between amyloid-β and tau in Alzheimer’s disease’, 23(10), pp. 1183–1193. Available at: https://doi.org/10.1038/s41593-020-0687-6.

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Harris, S.S. et al. (2020) ‘Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer’s Disease’, 107(3), pp. 417–435. Available at: https://doi.org/10.1016/j.neuron.2020.06.005.

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Pigoni, M. et al. (2020) ‘Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3’, 39(15). Available at: https://doi.org/10.15252/embj.2019103457.

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Busche, M.A. (2019) ‘Tau suppresses neuronal activity in vivo, even before tangles form’, 142(4), pp. 843–846. Available at: https://doi.org/10.1093/brain/awz060.

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Busche, M.A. et al. (2019) ‘Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo’, 22(1), pp. 57–64. Available at: https://doi.org/10.1038/s41593-018-0289-8.

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Zott, B. et al. (2018) ‘What happens with the circuit in Alzheimer’s disease in mice and humans?’, 41, pp. 277–297. Available at: https://doi.org/10.1146/annurev-neuro-080317-061725.

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Busche, M.A. (2018) ‘In vivo two-photon calcium imaging of hippocampal neurons in Alzheimer mouse models’, in Methods in Molecular Biology. Humana Press Inc.humana@humanapr.com (Methods in Molecular Biology), pp. 341–351. Available at: https://doi.org/10.1007/978-1-4939-7704-8_23.

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Schweyer, K. et al. (2018) ‘Pearls & Oy-sters: Ocular motor apraxia as essential differential diagnosis to supranuclear gaze palsy’, 90(10), pp. 482–485. Available at: https://doi.org/10.1212/wnl.0000000000005069.

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Keskin, A.D. et al. (2017) ‘BACE inhibition-dependent repair of Alzheimer’s pathophysiology’, 114(32), pp. 8631–8636. Available at: https://doi.org/10.1073/pnas.1708106114.

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Busche, M.A., Kekuš, M. and Förstl, H. (2017) ‘Connections between sleep and Alzheimerʼs disease: Insomnia, amnesia and amyloid Wie Schlaf und Alzheimer-Krankheit zusammenhängen: Insomnie, Amnesie und Amyloid’, 88(3), pp. 215–221. Available at: https://doi.org/10.1007/s00115-016-0122-0.

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Busche, M.A. and Konnerth, A. (2016) ‘Impairments of neural circuit function in Alzheimer’s disease’, 371(1700). Available at: https://doi.org/10.1098/rstb.2015.0429.

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Grimmer, T. et al. (2015) ‘Trends of patient referral to a memory clinic and towards earlier diagnosis from 1985-2009’, 27(12), pp. 1939–1944. Available at: https://doi.org/10.1017/s104161021500157x.

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Busche, M.A. et al. (2015) ‘Decreased amyloid-β and increased neuronal hyperactivity by immunotherapy in Alzheimer’s models’, 18(12), pp. 1725–1727. Available at: https://doi.org/10.1038/nn.4163.

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Busche, M.A. et al. (2015) ‘Rescue of long-range circuit dysfunction in Alzheimer’s disease models’, 18(11), pp. 1623–1630. Available at: https://doi.org/10.1038/nn.4137.

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Willem, M. et al. (2015) ‘σ-Secretase processing of APP inhibits neuronal activity in the hippocampus’, 526(7573), pp. 443–447. Available at: https://doi.org/10.1038/nature14864.

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Busche, M.A. and Konnerth, A. (2015) ‘Neuronal hyperactivity - A key defect in Alzheimer’s disease?’, 37(6), pp. 624–632. Available at: https://doi.org/10.1002/bies.201500004.

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Busche, M.A. et al. (2012) ‘Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer’s disease’, 109(22), pp. 8740–8745. Available at: https://doi.org/10.1073/pnas.1206171109.

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Busche, M.A. et al. (2008) ‘Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer’s disease’, 321(5896), pp. 1686–1689. Available at: https://doi.org/10.1126/science.1162844.

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Eichhoff, G., Busche, M.A. and Garaschuk, O. (2008) ‘In vivo calcium imaging of the aging and diseased brain’, 35(SUPPL. 1). Available at: https://doi.org/10.1007/s00259-007-0709-6.

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