Faculty of Medicine
Faculty of Medicine
UNIverse - Public Research Portal
Head of Research Unit
profile pictureMALE
Prof. Dr. med.
Alexander Navarini
Research Group Alexander Navarini

Research Focus

Immunology & Infectious Diseases


Area of Research

Genetics and pathophysiology of inflammatory skin diseases, especially neutrophilic dermatoses; Image-based classification of dermatoses using machine learning


Approved Research Projects

Investigator-initiated trials:

• IRASPEN Registry

• APRESCALP Study

• SDNTT Registry

• MELVEC Study

• Computer-based Skin Aging Simulation for Skin Cancer Prevention

• AcneDect Study

• Skin biopsies and blood for epigenetics

• Cutaneous surgery disfigurement trial

• Skinobi: Skin moisture and pigmentation levels

• The Color of Itch; Itch Modification by Color Viewing

Industry-sponsored trials:

• POSITIVE

• MEASURE-UP1

• VALUE Registry

• Serena Registry

• BI 1368-0016: moderate to severe Palmoplantar Pustulosis (PPP)

• BI 1368-0013: Generalized Pustular Psoriasis (GPP)


Collaborations

National Collaborations

  • Swiss Dermatology Network for Targeted Therapies (PI Navarini)

International Collaborations

  • International Rare and Severe Psoriasis Expert Network (PI Navarini)


Ongoing Research Projects

Investigator-initiated trials:

  • International Rare And Severe Psoriasis Expert Network (IRASPEN) Study: NCT04359394
  • Apremilast Treatment for Pruritus and Quality of Life in Scalp Psoriasis (APRESCALP): NCT03553433
  • Swiss Dermatology Network of Targeted Therapies (SDNTT) Registry: NCT01706692
  • Acne Detection Software (AcneDect) (AcneDect) NCT04060160
  • Clinical performance of the new artificial intelligence-powered 3D total body photography system VECTRA® in early melanoma detection and its impact on patients’ burden of disease: A prospective cohort study in a real-world setting (Short title: Melanoma Detection in Switzerland With VECTRA (Acronym: MELVEC)): NCT04605822
  • A prospective observational multicenter study to evaluate the performance and patient acceptance of the ATBM master device for automated total body mapping (Acronym: ATBM-MASTER international study): NCT04605822
  • Total body dermoscopic evaluation of pregnancy-related changes in melanocytic nevi using the FotoFinder ATBM master system and the impact of artificial intelligence assisted examinations on the patients’ skin cancer screening experience: A prospective two-arm controlled observational study. (Acronym: PREM = Pregnancy-related changes in melanocytic nevi) (EKNZ: 2020-02494)
  • Computer-based Skin Aging Simulation for Skin Cancer Prevention: NCT04532437
  • Acceptance of teledermatology compared to face-to-face consultation from the providers’ and users’ perspectives: NCT04495036
  • German-speaking Melanoma Patients willingness to tolerate toxicity during adjuvant treatment (GERMELATOX-A)
  • Skin biopsies and blood for epigenetics
  • Skinobi: Skin moisture and pigmentation levels
  • Patient Reported Outcome Measures After Treatment of Skin Cancers on the Face: NCT04485442 (gemeinsames Projekt mit Plastischer Chirurgie)

Industry-sponsored trials:

  • POSITIVE
  • MEASURE-UP1
  • VALUE