Faculty of Medicine
Faculty of Medicine
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[FG] Hemkens Lars

Publications

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Boesen, K. et al. (2024) ‘Publicly available continuously updated topic specific databases of randomised clinical trials: A scoping review’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2024.11.18.24317477.

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Elgersma, I.H. et al. (2024) ‘Effect of Wearing Glasses for Prevention of SARS-CoV-2 on Visits to Health Care Providers - Additional Results from a Randomized Controlled Trial’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2024.08.29.24311868.

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Pittelkow, M.-M. et al. (2024) ‘Strength of Statistical Evidence for the Efficacy of Cancer Drugs: A Bayesian Re-Analysis of Randomized Trials Supporting FDA Approval’, Journal of Clinical Epidemiology, p. 111479. Available at: https://doi.org/10.1016/j.jclinepi.2024.111479.

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Boesen, K et al. (2024) ‘Rationale and design of the Cancer Immunotherapy Evidence Living (CIEL) Library: A continuously updated clinical trial database of cancer immunotherapies’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2024.04.26.24306436.

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Woelfle, T. et al. (2024) ‘Benchmarking Human-AI Collaboration for Common Evidence Appraisal Tools’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2024.04.21.24306137.

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Janiaud, Perrine et al. (2024) ‘MultiSCRIPT-Cycle 1- A Pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in Multiple Sclerosis: a study protocol for a randomized clinical trial’, medRxiv [Preprint]. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2024.03.22.24304720.

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Nickolls, B.J. et al. (2024) ‘Randomised trials conducted using cohorts: a scoping review’, BMJ Open, 14(3). Available at: https://doi.org/10.1136/bmjopen-2023-075601.

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Jagoda, F.A. et al. (2024) ‘Involvement of family caregivers in dementia care research: a scoping review protocol’. Research Square Platform LLC. Available at: https://doi.org/10.21203/rs.3.rs-3292528/v1.

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Alonso, Ana Karen Macias et al. (2024) ‘Definitions of digital biomarkers: a systematic mapping of the biomedical literature’, BMJ Health and Care Informatics, 31. Available at: https://doi.org/10.1136/bmjhci-2023-100914.

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Axfors, Cathrine et al. (2024) ‘Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials(Nature Communications, (2021), 12, (1), 10.1038/s41467-021-22446-z)’, Nature Communications, 15. Available at: https://doi.org/10.1038/s41467-024-45360-6.

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Bauernschmidt, Dorothee et al. (2024) ‘The Implementation Success of Technology-Based Counseling in Dementia Care: Scoping Review’, JMIR Aging, 7. Available at: https://doi.org/10.2196/51544.

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Beer, Thomas et al. (2024) ‘Exploring the Experiences of Times Without Care and Encounters in Persons With Dementia in the Swiss and German Nursing Home and Domiciliary Care Settings: Protocol for an Ethnographic Multimethods Study’, JMIR Research Protocols, 13. Available at: https://doi.org/10.2196/58190.

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Djulbegovic, Benjamin et al. (2024) ‘What is the probability that higher versus lower quality of evidence represents true effects estimates?’, Journal of Evaluation in Clinical Practice [Preprint]. Available at: https://doi.org/10.1111/jep.14160.

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Djulbegovic, Benjamin et al. (2024) ‘High certainty evidence is stable and trustworthy, whereas evidence of moderate or lower certainty may be equally prone to being unstable’, Journal of Clinical Epidemiology, 171. Available at: https://doi.org/10.1016/j.jclinepi.2024.111392.

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Eppel-Meichlinger, Jasmin et al. (2024) ‘(How) Do We Theorize?: A Focused Mapping Review and Synthesis of Theoretical Nursing Research in the German-Speaking Area’, Advances in Nursing Science, 47, pp. E58–E74. Available at: https://doi.org/10.1097/ans.0000000000000498.

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Fretheim, Atle, Solberg, Runar Barstad and Hemkens, Lars G. (2024) ‘The polarised discourse around face masks is hindering constructive debate’, BMJ [Preprint]. Available at: https://doi.org/10.1136/bmj.q1661.

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Heinen, Lena et al. (2024) ‘The optimal approach for retrieving systematic reviews was achieved when searching MEDLINE and Epistemonikos in addition to reference checking: a methodological validation study’, BMC Medical Research Methodology, 24. Available at: https://doi.org/10.1186/s12874-024-02384-2.

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Hirt, J. et al. (2024) ‘Recruiting Persons With Dementia: A Systematic Review of Facilitators, Barriers, and Strategies’, American Journal of Alzheimer’s Disease and other Dementias, 39. Available at: https://doi.org/10.1177/15333175241276443.

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Hirt, Julian et al. (2024) ‘Clinical trial evidence of quality-of-life effects of disease-modifying therapies for multiple sclerosis: a systematic analysis’, Journal of Neurology [Preprint]. Available at: https://doi.org/10.1007/s00415-024-12366-5.

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Hirt, Julian et al. (2024) ‘Searching a methods topic: practical challenges and implications for search design’, Journal of Clinical Epidemiology. 30.10.2023, 166. Available at: https://doi.org/10.1016/j.jclinepi.2023.10.017.

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Hirt, Julian et al. (2024) ‘Use of pragmatic randomized trials in multiple sclerosis: A systematic overview’, Multiple Sclerosis Journal, 30, pp. 463–478. Available at: https://doi.org/10.1177/13524585231221938.

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Hirt, Julian et al. (2024) ‘Guidance on terminology, application, and reporting of citation searching: the TARCiS statement’, BMJ. 09.05.2024, 385. Available at: https://doi.org/10.1136/bmj-2023-078384.

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Hirt, Julian et al. (2024) ‘Nurse-led physical activity interventions for people with dementia in nursing homes: A systematic review on intervention characteristics and implementation facilitators/barriers’, International Journal of Nursing Studies, 154. Available at: https://doi.org/10.1016/j.ijnurstu.2024.104756.

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Jäger, Peter et al. (2024) ‘Evidence-based practice in Bachelor of Nursing programmes in Austria, Germany, and Switzerland: A survey of general conditions, teaching content and methods’, Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen [Preprint]. Available at: https://doi.org/10.1016/j.zefq.2024.01.006.

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Jagoda, Franziska Anushi et al. (2024) ‘Involvement of family caregivers in dementia care research: a scoping review protocol’, Systematic Reviews, 13. Available at: https://doi.org/10.1186/s13643-024-02696-w.

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Lüthi, Hualin et al. (2024) ‘Effect of dulaglutide in promoting abstinence during smoking cessation: 12-month follow-up of a single-centre, randomised, double-blind, placebo-controlled, parallel group trial’, eClinicalMedicine, 68. Available at: https://doi.org/10.1016/j.eclinm.2024.102429.

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Muente, Catharina et al. (2024) ‘Validated geographic search filters for bibliographic databases: a scoping review protocol’, JBI Evidence Synthesis, 22, pp. 441–446. Available at: https://doi.org/10.11124/jbies-23-00445.

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Niederberger, Marlen et al. (2024) ‘Delphi studies in social and health sciences—Recommendations for an interdisciplinary standardized reporting (DELPHISTAR). Results of a Delphi study’, PLoS ONE, 19. Available at: https://doi.org/10.1371/journal.pone.0304651.

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Pachanov, Alexander et al. (2024) ‘Development and validation of a geographic search filter for MEDLINE (PubMed) to identify studies about Germany’, Research Synthesis Methods, 15, pp. 1147–1160. Available at: https://doi.org/10.1002/jrsm.1763.

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Puljak, Livia et al. (2024) ‘Methods proposed for monitoring the implementation of evidence-based research: a cross-sectional study’, Journal of Clinical Epidemiology, 168, p. 111247. Available at: https://doi.org/10.1016/j.jclinepi.2024.111247.

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Skudlik, Stefanie et al. (2024) ‘Reply to Commentary to Skudlik et al. (2023): why a scoping review and why only Germany?’, BMC Nursing, 23. Available at: https://doi.org/10.1186/s12912-024-02078-6.

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Solberg, Runar Barstad et al. (2024) ‘Personal protective effect of wearing surgical face masks in public spaces on self-reported respiratory symptoms in adults: pragmatic randomised superiority trial’, BMJ [Preprint]. Available at: https://doi.org/10.1136/bmj-2023-078918.

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Vanmeenen, M. et al. (2024) ‘Comparing different scoping and mapping review methodologies: A practical example using the nursing mobile workstation’, Journal of Nursing Scholarship [Preprint]. Available at: https://doi.org/10.1111/jnu.13005.

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Wei, Lili et al. (2024) ‘Methodological Challenges when Using Routinely Collected Health Data for Research: A scoping review.’ Available at: https://doi.org/10.23889/ijpds.v9i5.2610.

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Woelfle, Tim et al. (2024) ‘Benchmarking Human–AI collaboration for common evidence appraisal tools’, Journal of Clinical Epidemiology, 175. Available at: https://doi.org/10.1016/j.jclinepi.2024.111533.

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Zietz, Annaelle et al. (2024) ‘Enhancement of STroke REhabilitation with Levodopa (ESTREL): Rationale and design of a randomized placebo-controlled, double blind superiority trial’, European Stroke Journal [Preprint]. Available at: https://doi.org/10.1177/23969873241255867.

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Hirt, Julian et al. (2023) The TARCiS statement: Guidance on terminology, application, and reporting of citation searching. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2023.10.25.23297543.

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Holst, M. et al. (2023) ‘Frequency of multiple changes to prespecified primary outcomes of clinical trials completed between 2009 and 2017 in German university medical centers: A meta-research study’, PLoS Medicine, 20(10 October). Available at: https://doi.org/10.1371/journal.pmed.1004306.

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Alonso, A.K.M. et al. (2023) ‘Definitions of digital biomarkers: a systematic mapping of the biomedical literature’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2023.09.01.23294897.

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Dal-Ré R et al. (2023) ‘Using the phases of clinical development of medicines to describe clinical trials assessing other interventions is widespread but not useful.’, Journal of clinical epidemiology [Preprint]. Available at: https://doi.org/10.1016/j.jclinepi.2023.07.011.

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Goldkuhle M et al. (2023) ‘GRADE concept 4: rating the certainty of evidence when study interventions or comparators differ from PICO targets.’, Journal of clinical epidemiology, 159, pp. 40–48. Available at: https://doi.org/10.1016/j.jclinepi.2023.04.018.

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Pittelkow, M.-M. et al. (2023) Strength of Statistical Evidence for the Efficacy of Cancer Drugs: A Bayesian Re-Analysis of Trials Supporting FDA Approval. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2023.06.30.23292074.

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Bauernschmidt, Dorothee et al. (2023) ‘Technology-Based Counselling for People with Dementia and Their Informal Carers: A Systematic Review and Meta-Analysis’, Journal of Alzheimer’s disease : JAD, 93, pp. 891–906. Available at: https://doi.org/10.3233/jad-221194.

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Cobey KD et al. (2023) ‘Community consensus on core open science practices to monitor in biomedicine.’, PLoS biology, 21(1), p. e3001949. Available at: https://doi.org/10.1371/journal.pbio.3001949.

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Ebrahimi, Fahim et al. (2023) ‘Colchicine for the secondary prevention of cardiovascular events’, Cochrane Database of Systematic Reviews. 29.08.2023, 2023(8). Available at: https://doi.org/10.1002/14651858.cd014808.

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Gloy, Viktoria et al. (2023) ‘The evidence base of US Food and Drug Administration approvals of novel cancer therapies from 2000 to 2020’, International Journal of Cancer, 152, pp. 2474–2484. Available at: https://doi.org/10.1002/ijc.34473.

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Goldkuhle, Marius et al. (2023) ‘Meta-epidemiological review identified variable reporting and handling of time-to-event analyses in publications of trials included in meta-analyses of systematic reviews’, Journal of Clinical Epidemiology, 159, pp. 174–189. Available at: https://doi.org/10.1016/j.jclinepi.2023.05.023.

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Hirt, J. et al. (2023) ‘Introducing the Library of Guidance for Health Scientists (LIGHTS): a living database for methods guidance’, JAMA Netw Open, 6(2), p. e2253198. Available at: https://doi.org/10.1001/jamanetworkopen.2022.53198.

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Hirt, Julian et al. (2023) ‘Exploring experiences of times without care and encounters in dementia: protocol for a living and adaptive evidence map’, BMJ Open, 13. Available at: https://doi.org/10.1136/bmjopen-2023-075664.

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Hirt, Julian et al. (2023) ‘Meta-research on pragmatism of randomized trials: rationale and design of the PragMeta database’, Trials, 24. Available at: https://doi.org/10.1186/s13063-023-07474-y.

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Hirt, Julian et al. (2023) ‘Robustness of reported postacute health outcomes in children with SARS-CoV-2 infection: A systematic review’, Archives of Disease in Childhood, 108, pp. 498–505. Available at: https://doi.org/10.1136/archdischild-2022-324455.

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Hirt, Julian et al. (2023) ‘Citation tracking for systematic literature searching: A scoping review’, Research Synthesis Methods, 14(3), pp. 563–579. Available at: https://doi.org/10.1002/jrsm.1635.

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Hirt, J. et al. (2023) ‘Nurse-Led Physical Activity Interventions for People with Dementia in Nursing Homes:A Systematic Review on Intervention Characteristics and Implementation Facilitators/Barriers’. Elsevier BV. Available at: https://doi.org/10.2139/ssrn.4388294.

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Lengsfeld, Sophia et al. (2023) ‘Glucagon-like peptide-1 analogues: a new way to quit smoking? (SKIP)—a structured summary of a study protocol for a randomized controlled study’, Trials, 24. Available at: https://doi.org/10.1186/s13063-023-07164-9.

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Lengsfeld, Sophia et al. (2023) ‘Effect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial’, eClinicalMedicine, 57. Available at: https://doi.org/10.1016/j.eclinm.2023.101865.

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Skudlik, Stefanie et al. (2023) ‘Challenges and care strategies associated with the admission to nursing homes in Germany: a scoping review’, BMC Nursing, 22. Available at: https://doi.org/10.1186/s12912-022-01139-y.

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Eppel-Meichlinger, J. et al. (2022) ‘(How) Do we theorize? A focused mapping review and synthesis of theoretical nursing research in the German-speaking area of Europe’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2022.12.21.22283767.

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Hirt, Julian et al. (2022) ‘Library of Guidance for Health Scientists (LIGHTS): Eine neue Datenbank für methodische Leitlinien in der klinischen Forschung’, GMS Medizin - Bibliothek - Information. 20.12.2022, 22(2). Available at: https://doi.org/10.3205/mbi000546.

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Fretheim A et al. (2022) ‘Effect of Wearing Glasses on Risk of Infection With SARS-CoV-2 in the Community: A Randomized Clinical Trial.’, JAMA network open, 5(12), p. e2244495. Available at: https://doi.org/10.1001/jamanetworkopen.2022.44495.

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Hirt J, Janiaud P and Hemkens LG (2022) ‘Randomized trials on non-pharmaceutical interventions for COVID-19: a scoping review.’, BMJ evidence-based medicine, 27(6), pp. 334–344. Available at: https://doi.org/10.1136/bmjebm-2021-111825.

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Young, K. et al. (2022) ‘Management of Toxicity and Side Effects of Systemic Therapy for Renal Cell Carcinoma’, Société Internationale d’Urologie Journal, 3(6), pp. 484–498. Available at: https://doi.org/10.48083/syab9165.

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Hirt J, Janiaud P and Hemkens LG (2022) ‘Clinical trial research agenda on COVID-19 - the first two years in Germany and beyond.’, Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, 174, pp. 32–42. Available at: https://doi.org/10.1016/j.zefq.2022.08.003.

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Fendler, A. et al. (2022) ‘Functional immune responses against SARS-CoV-2 variants of concern after fourth COVID-19 vaccine dose or infection in patients with blood cancer’, Cell Reports Medicine, 3(10). Available at: https://doi.org/10.1016/j.xcrm.2022.100781.

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Atila C et al. (2022) ‘Central diabetes insipidus from a patient’s perspective: management, psychological co-morbidities, and renaming of the condition: results from an international web-based survey’, The Lancet Diabetes and Endocrinology, 10(10), pp. 700–709. Available at: https://doi.org/10.1016/s2213-8587(22)00219-4.

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Hirt, J. et al. (2022) Citation tracking for systematic literature searching: a scoping review. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2022.09.29.22280494.

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Ewald H et al. (2022) ‘Searching two or more databases decreased the risk of missing relevant studies: a metaresearch study.’, Journal of clinical epidemiology, 149, pp. 154–164. Available at: https://doi.org/10.1016/j.jclinepi.2022.05.022.

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Hirt J et al. (2022) ‘A systematic survey of methods guidance suggests areas for improvement regarding access, development, and transparency.’, Journal of clinical epidemiology, 149, pp. 217–226. Available at: https://doi.org/10.1016/j.jclinepi.2022.05.005.

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Fretheim, A. et al. (2022) ‘Glasses Against transmission of SARS-CoV-2 in the community (GLASSY): a pragmatic randomized trial’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2022.07.31.22278223.

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Hemmig AK et al. (2022) ‘Subclinical giant cell arteritis in new onset polymyalgia rheumatica A systematic review and meta-analysis of individual patient data.’, Seminars in arthritis and rheumatism, 55, p. 152017. Available at: https://doi.org/10.1016/j.semarthrit.2022.152017.

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Hirt J et al. (2022) ‘Staff-to-resident abuse in nursing homes: a scoping review.’, BMC geriatrics, 22(1), p. 563. Available at: https://doi.org/10.1186/s12877-022-03243-9.

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Cobey, K.D. et al. (2022) ‘Establishing a core set of open science practices in biomedicine: a modified Delphi study’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2022.06.27.22276964.

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Djulbegovic B et al. (2022) ‘High quality (certainty) evidence changes less often than low-quality evidence, but the magnitude of effect size does not systematically differ between studies with low versus high-quality evidence.’, Journal of evaluation in clinical practice, 28(3), pp. 353–362. Available at: https://doi.org/10.1111/jep.13657.

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Schmitt AM et al. (2022) ‘Characteristics and survival of patients with cancer with intended off-label use-a cohort study.’, BMJ open, 12(5), p. e060453. Available at: https://doi.org/10.1136/bmjopen-2021-060453.

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Hirt, J. et al. (2022) ‘Validity of reported post-acute health outcomes in children with SARS-CoV-2 infection: a systematic review’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2022.03.18.22272582.

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De Marchis GM et al. (2022) ‘Association of the COVID-19 outbreak with acute stroke care in Switzerland.’, European journal of neurology, 29(3), pp. 724–731. Available at: https://doi.org/10.1111/ene.15209.

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Abraham, Jens et al. (2022) ‘Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings’, Cochrane Database of Systematic Reviews, 2022. Available at: https://doi.org/10.1002/14651858.cd012476.pub2.

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Gryaznov, D. et al. (2022) ‘Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE)’, BMJ Open, 12(5), p. e053417. Available at: https://doi.org/10.1136/bmjopen-2021-053417.

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Hemkens LG, Juszczak E and Thombs BD (2022) ‘Reporting transparency and completeness in trials: Paper 1: Introduction - Better reporting for disruptive clinical trials using routinely collected data’, 141. Available at: https://doi.org/10.1016/j.jclinepi.2021.09.017.

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Imran M et al. (2022) ‘Reporting transparency and completeness in trials: Paper 3 – trials conducted using administrative databases do not adequately report elements related to use of databases’, Journal of Clinical Epidemiology, 141, pp. 187–197. Available at: https://doi.org/10.1016/j.jclinepi.2021.09.010.

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McCall SJ et al. (2022) ‘Reporting transparency and completeness in trials: Paper 4 - reporting of randomised controlled trials conducted using routinely collected electronic records – room for improvement’, Journal of Clinical Epidemiology, 141, pp. 198–209. Available at: https://doi.org/10.1016/j.jclinepi.2021.09.011.

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Mc Cord KA et al. (2022) ‘Reporting transparency and completeness in Trials: Paper 2 - reporting of randomised trials using registries was often inadequate and hindered the interpretation of results’, Journal of Clinical Epidemiology, 141, pp. 175–186. Available at: https://doi.org/10.1016/j.jclinepi.2021.09.012.

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Schwab, Simon et al. (2022) ‘Ten simple rules for good research practice’, PLoS Computational Biology, 18(6), p. e1010139. Available at: https://doi.org/10.1371/journal.pcbi.1010139.

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Speich, B. et al. (2022) ‘Nonregistration, discontinuation, and nonpublication of randomized trials: a repeated metaresearch analysis’, PLoS Med, 19(4), p. e1003980. Available at: https://doi.org/10.1371/journal.pmed.1003980.

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Hirt J., Vetsch J. and Heinrich S. (2021) ‘Facilitators and barriers to implement nurse-led physical activities for people with dementia in nursing homes: A protocol for a mixed-methods systematic review’, BMJ Open, 11(12). Available at: https://doi.org/10.1136/bmjopen-2021-056353.

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Hirt J et al. (2021) ‘Technology-based counselling in dementia (TeCoDem): study protocol of a mixed-methods systematic review with qualitative comparative analysis and meta-analysis.’, BMJ open, 11(12), p. e054157. Available at: https://doi.org/10.1136/bmjopen-2021-054157.

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Hirt, J. et al. (2021) ‘Staff-to-Residence Abuse in Nursing Homes: A Scoping Review’. Research Square Platform LLC. Available at: https://doi.org/10.21203/rs.3.rs-1121281/v1.

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Axfors C et al. (2021) ‘Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials’, BMC Infectious Diseases, 21(1), p. 1170. Available at: https://doi.org/10.1186/s12879-021-06829-7.

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Axfors C et al. (2021) ‘Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials (Nature Communications, (2021), 12, 1, (2349), 10.1038/s41467-021-22446-z)’, 12(1). Available at: https://doi.org/10.1038/s41467-021-23559-1.

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Axfors C et al. (2021) ‘Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials’, Nature Communications, 12(1), p. 2349. Available at: https://doi.org/10.1038/s41467-021-22446-z.

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Janiaud P et al. (2021) ‘Validity of observational evidence on putative risk and protective factors: appraisal of 3744 meta-analyses on 57 topics’, BMC Medicine, 19(1), p. 157. Available at: https://doi.org/10.1186/s12916-021-02020-6.

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Speich B et al. (2021) ‘A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®’, Trials, 22(1), p. 724. Available at: https://doi.org/10.1186/s13063-021-05664-0.

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McLennan, Stuart et al. (2021) ‘Barriers and Facilitating Factors for Conducting Systematic Evidence Assessments in Academic Clinical Trials’, JAMA Network Open, 4(11), p. E2136577. Available at: https://doi.org/10.1001/jamanetworkopen.2021.36577.

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Schwab, S. et al. (2021) ‘Ten simple rules for good research practice’. Center for Open Science. Available at: https://doi.org/10.31219/osf.io/am5ck.

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Taji Heravi A et al. (2021) ‘Evaluation of Planned Subgroup Analysis in Protocols of Randomized Clinical Trials’, JAMA Network Open, 4(10), p. e2131503. Available at: https://doi.org/10.1001/jamanetworkopen.2021.31503.

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Hemkens LG (2021) ‘[Benefit assessment of digital health applications-challenges and opportunities].’, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 64(10), pp. 1269–1277. Available at: https://doi.org/10.1007/s00103-021-03413-x.

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Hemkens LG and Goodman SN (2021) ‘Randomized COVID-19 vaccination rollout can offer direct real-world evidence’, Journal of Clinical Epidemiology, 138, pp. 199–202. Available at: https://doi.org/10.1016/j.jclinepi.2021.05.014.

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Kappos EA et al. (2021) ‘Prepectoral versus subpectoral implant-based breast reconstruction after skin-sparing mastectomy or nipple-sparing mastectomy (OPBC-02/ PREPEC): A pragmatic, multicentre, randomised, superiority trial’, BMJ Open, 11(9), p. e045239. Available at: https://doi.org/10.1136/bmjopen-2020-045239.

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Janiaud P, Hemkens LG and Ioannidis JPA (2021) ‘Challenges and Lessons Learned From COVID-19 Trials: Should We Be Doing Clinical Trials Differently?’, Canadian Journal of Cardiology, 37(9), pp. 1353–1364. Available at: https://doi.org/10.1016/j.cjca.2021.05.009.

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Hirt, J., Janiaud, P. and Hemkens, L.G. (2021) ‘Randomized trials on non-pharmaceutical interventions for COVID-19 as of August 2021: a meta-epidemiological analysis’. Cold Spring Harbor Laboratory. Available at: https://doi.org/10.1101/2021.08.20.21261687.

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Hanf, M., Hirt, J. and Van Den Akker, M. (2021) ‘Primary care professionals” attitudes towards digital health interventions for common mental disorders: Study protocol for a mixed methods systematic review’, BMJ Open, 11(6). Available at: https://doi.org/10.1136/bmjopen-2020-045657.

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URLs