[FG] Hemkens Lars

Research Focus: Clinical Epidemiology, Public Health & Health Systems

PRAGMATIC EVIDENCE LAB

OUR LABORATORY

… works at the intersection of clinical research, evidence-based medicine, and digital health.

• We focus on pragmatic trials providing randomized real-world evidence, facilitated by digital biomarkers and routinely collected data.
• We apply our work across the full spectrum of clinical medicine and public health, with a focus on complex, rapidly evolving areas such as neuroscience.

OUR MISSION

… is to make evidence most useful for healthcare.

• We investigate the nature and physiology of pragmatic evidence.
• We analyze the processes and functions that determine pragmatism.
• We explore novel methods and study designs that better integrate research in routine care.

OUR PROJECTS

… fall within four main themes:

• Pragmatic trials and real-world evidence – designing studies to generate evidence that is most useful for patient care.
• Evidence-based decision making – providing evidence to inform healthcare decisions and regulatory science.
• Digital health – integrating research into routine care through innovative tools.
• Meta-research – promoting and exploring good research practices, Open Science and how research is being conducted, reported and interpreted.

Beyond these

…. we are teaching concepts of pragmatic trials, real-world evidence, comparative effectiveness research, good research practices, evidence syntheses, and evidence-based practice.

@ RC2NB

• We are part of the “Pragmatic Trials and Real-World Evidence” workstream, dedicated to translating innovation into research and care.
• We leverage RC2NB’s interdisciplinary clinical, technological and methodological expertise to develop, evaluate, and apply novel approaches to pragmatic, decentralized, and remote trials using real-world data.
• We aim to establish a learning research and care system to rapidly integrate and continually evaluate research findings in routine care.