Faculty of Medicine
Faculty of Medicine
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[FG] Betz Matthias

Research Group Matthias Betz

Area of Research

Our research is focused on the endocrine factors involved in human thermogenesis and energy metabolism. Specifically, we investigate human brown adipose tissue and cold induced thermogenesis.


Approved Research Projects

2015 – 2018 Research grant, Goldschmid-Jacobson Foundation / Medical Faculty, University of Basel

2015 Young Independent Investigator Grant of the Swiss Society for Endocrinology and Diabetes (SGED)

2016 SNSF ambizione SCORE grant for research project on influence of glucocorticoids on human brown adipose tissue

2017 Grant from Bangerter-Rhyner foundation for research project on brown adipose tissue 

2021 – 2025 SNSF Project grant: Therapeutic Targeting of the cAMP and cGMP Pathway to Increase Brown Adipose Tissue Activity in Humans


Collaborations

National Collaborations

- Prof. Christian Wolfrum, Department of Health Sciences and Technology, ETH-Zürich

- Prof. Nicola Zamboni, Institute of Systems Biology, ETH-Zürich

- Prof. Dr. Irene Burger, Dept. of Nuclear Medicine, University Hospital Zurich

- Prof. Ender Konukoglu, ETH Zurich, Biomedical Image Computing

- Prof. Bart Deplancke, EPFL, Lausanne

International Collaborations

- Prof. Sven Enerbäck, University of Gothenburg, Sahlgrenska Akademin

- Prof. Dr. Jörg Heeren, University Hospital Eppendorf, Hamburg, Germany


Ongoing Research Projects

NEXT Trial: Effect of Glyceroltrinitrate on Human Energy Expenditure and Brown Adipose Tissue Thermogenesis (NCT05711199)

BANDIT Trial: Brown Adipose Tissue as Nutrient Buffer Through Diet Induced Thermogenesis (NCT06078345)

 

Completed Research Projects

ASCENT Trial: Beta 2 Adrenergic Stimulation vs Cold Exposure to Activate Human Brown Adipose Tissue (Clinical trials NCT05294965)

InoBAT Trial: Inosine Energy Expenditure Study (Clinical trials NCT04476238)

GlucoBAT Trial: Influence of short-term high dose glucocorticoid administration on brown adipose tissue function (NCT03269747)

HEAT Trial: Influence of anti-adrenergic therapy on energy metabolism in patients with primary hyperthyroidism (NCT03379181)

MATCH-Study: Metabolomics of Thyroid Hormones in Humans

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