Publications
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Tsitopoulou, Maria et al. (2024) ‘1,4-Pd Migration-Enabled Synthesis of Fused 4-Membered Rings’, Journal of the American Chemical Society. 05.07.2024, 146(28), pp. 18811–18816. Available at: https://doi.org/10.1021/jacs.4c04701.
Geraci, Andrea and Baudoin, Olivier (2024) ‘Fe-Catalyzed α-C(sp 3 )−H Amination of N-Heterocycles’, Angewandte Chemie - International Edition [Preprint]. Available at: https://doi.org/10.1002/anie.202417414.
Miyakoshi, Takeru et al. (2024) ‘Studies towards the Enantioselective Synthesis of Cryptowolinol via Pd<sup>0</sup>-Catalyzed C(sp<sup>3</sup>)-H Arylation/Parallel Kinetic Resolution’, Organic Letters, null. Available at: https://doi.org/10.1021/acs.orglett.4c00386.
Vyhivskyi, Oleksandr and Baudoin, Olivier (2024) ‘Total Synthesis of the Diterpenes (+)-Randainin D and (+)-Barekoxide via Photoredox-Catalyzed Deoxygenative Allylation’, Journal of the American Chemical Society [Preprint]. Available at: https://doi.org/10.1021/jacs.4c02224.
Kudashev, Anton et al. (2023) ‘Methylene C(sp³)−H Arylation Enables the Stereoselective Synthesis and Structure Revision of Indidene Natural Products’, Angewandte Chemie International Edition. 23.11.2023, 63(1). Available at: https://doi.org/10.1002/anie.202316103.
Geraci, Andrea et al. (2023) ‘Iridium(III)-Catalyzed Intermolecular C(sp³)-H Amidation for the Synthesis of Chiral 1,2-Diamines’, Angewandte Chemie International Edition, 62(42), p. e202309263. Available at: https://doi.org/10.1002/anie.202309263.
Guo, Shu-Min et al. (2023) ‘A C-H activation-based enantioselective synthesis of lower carbo[n]helicenes’, Nature chemistry, 15, pp. 872–880. Available at: https://doi.org/10.1038/s41557-023-01174-5.
Martynova, Ekaterina A. et al. (2023) ‘Simple synthetic access to [Au(IBiox)Cl] complexes’, Dalton Transactions, 52(22), pp. 7558–7563. Available at: https://doi.org/10.1039/d3dt01357j.
Salameh, Nihad et al. (2023) ‘A General Enantioselective C-H Arylation Using an Immobilized Recoverable Palladium Catalyst.’, ChemSusChem. 24.07.2023, 16(23). Available at: https://doi.org/10.1002/cssc.202300609.
Wheatley, Matthew et al. (2023) ‘Effect of α-Substitution on the Reactivity of C(sp³)-H Bonds in Pd⁰-Catalyzed C-H Arylation’, ACS Catalysis, 13, pp. 12563–12570. Available at: https://doi.org/10.1021/acscatal.3c03806.
Ferlin, Francesco et al. (2022) ‘C(sp³)−H Arylation Promoted by a Heterogeneous Palladium-N-Heterocyclic Carbene Complex in Batch and Continuous Flow’, ChemSusChem, 15(6), p. e202102736. Available at: https://doi.org/10.1002/cssc.202102736.
Miyakoshi, Takeru, Niggli, Nadja E. and Baudoin, Olivier (2022) ‘Remote Construction of N-Heterocycles via 1,4-Palladium Shift-Mediated Double C-H Activation’, Angewandte Chemie International Edition, 61(17), p. e202116101. Available at: https://doi.org/10.1002/anie.202116101.
Antien, Kevin et al. (2021) ‘A New Dioxazolone for the Synthesis of 1,2-Aminoalcohols via Iridium(III)-Catalyzed C(sp; 3; )-H Amidation’, Angewandte Chemie International Edition, 60(42), pp. 22948–22955. Available at: https://doi.org/10.1002/anie.202110019.
Baudoin, Olivier (2021) ‘A Personal Account on Industrial Collaborations in the Field of C-H Activation’, Chimia, 75(11), pp. 967–971. Available at: https://doi.org/10.2533/chimia.2021.967.
Kudashev, Anton and Baudoin, Olivier (2021) ‘Site-Selective Pd-Catalyzed C(sp3)-H Arylation of Heteroaromatic Ketones’, Chemistry - A European Journal, 27(70), pp. 17688–17694. Available at: https://doi.org/10.1002/chem.202103467.
Melot, Romain et al. (2021) ‘Palladium(0)-Catalyzed Enantioselective Intramolecular Arylation of Enantiotopic Secondary C-H Bonds’, Angewandte Chemie International Edition, 60(13), pp. 7245–7250. Available at: https://doi.org/10.1002/anie.202014605.
Niggli, Nadja E. and Baudoin, Olivier (2021) ‘Design of Chiral NHC-Carboxylates as Potential Ligands for Pd-Catalyzed Enantioselective C-H Activation’, Helvetica Chimica Acta, 104(3), p. e2100015. Available at: https://doi.org/10.1002/hlca.202100015.
Savary, David and Baudoin, Olivier (2021) ‘Enantioselective Pd0-Catalyzed C(sp2)-H Arylation for the Synthesis of Chiral Warped Molecules’, Angewandte Chemie International Edition, p. 10.1002/anie.202013303. Available at: https://doi.org/10.1002/anie.202013303.
Vyhivskyi, Oleksandr et al. (2021) ‘Chiral Catalysts for Pd-0-Catalyzed Enantioselective C-H Activation’, Chemistry - A European Journal, 27(4), pp. 1231–1257. Available at: https://doi.org/10.1002/chem.202003225.
Baudoin, Olivier (2020) ‘Multiple Catalytic C-H Bond Functionalization for Natural Product Synthesis’, Angewandte Chemie (International ed. in English), p. 10.1002/anie.202001224. Available at: https://doi.org/10.1002/anie.202001224.
Baumgartner, Yann and Baudoin, Olivier (2020) ‘One-Pot Alkene Hydroboration/Palladium-Catalyzed Migratory Suzuki−Miyaura Cross-Coupling’, ACS Catalysis, 10, pp. 10508–10515. Available at: https://doi.org/10.1021/acscatal.0c02755.
Carny, Tomas et al. (2020) ‘Synthesis of Amides and Esters by Palladium(0)-Catalyzed Carbonylative C(sp3)-H Activation’, Angewandte Chemie International Edition, 59(43), pp. 18980–18984. Available at: https://doi.org/10.1002/anie.202007922.
Clemenceau, Antonin et al. (2020) ‘Direct Synthesis of Cyclopropanes from gem-Dialkyl Groups through Double C-H Activation’, Journal of the American Chemical Society, 142(36), pp. 15355–15361. Available at: https://doi.org/10.1021/jacs.0c05887.
Nguyen, Qui-Hien et al. (2020) ‘Intermolecular Palladium(0)-Catalyzed Atropo-enantioselective C-H Arylation of Heteroarenes’, Journal of American Chemical Society, 142(5), pp. 2161–2167. Available at: https://doi.org/10.1021/jacs.9b12299.
Thesmar, Pierre et al. (2020) ‘Divergent Synthesis of Bioactive Dithiodiketopiperazine Natural Products Based on a Double C(sp3)−H Activation Strategy’, Chemistry - A European Journal, 26. Available at: https://doi.org/10.1002/chem.202003683.
Lin, Weilong, Zhang, Ke-Feng and Baudoin, Olivier (2019) ‘Regiodivergent enantioselective C-H functionalization of Boc-1,3-oxazinanes for the synthesis of beta(2)- and beta(3)-amino acids’, Nature Catalysis, 2(10), pp. 882–888. Available at: https://doi.org/10.1038/s41929-019-0336-1.
Melot, Romain, Craveiro, Marcus V. and Baudoin, Olivier (2019) ‘Total Synthesis of (Nor)illudalane Sesquiterpenes Based on a C(sp3)-H Activation Strategy’, Journal of Organic Chemistry, 84(20), pp. 12933–12945. Available at: https://doi.org/10.1021/acs.joc.9b01669.
Melot, Romain et al. (2019) ‘Divergent Enantioselective Synthesis of (Nor)illudalane Sesquiterpenes via Pd-0-Catalyzed Asymmetric C(sp(3))-H Activation’, Organic Letters, 21(3), pp. 812–815. Available at: https://doi.org/10.1021/acs.orglett.8b04086.
Rocaboy, Ronan, Anastasiou, Ioannis and Baudoin, Olivier (2019) ‘Redox-Neutral Coupling between Two C(sp3)-H Bonds Enabled by 1,4-Palladium Shift for the Synthesis of Fused Heterocycles’, Angewandte Chemie International Edition, 58(41), pp. 14625–14628. Available at: https://doi.org/10.1002/anie.201908460.
Rocaboy, Ronan and Baudoin, Olivier (2019) ‘1,4-Palladium Shift/C(sp(3))-H Activation Strategy for the Remote Construction of Five-Membered Rings’, Organic Letters, 21(5), pp. 1434–1437. Available at: https://doi.org/10.1021/acs.orglett.9b00187.
Royal, Titouan and Baudoin, Olivier (2019) ‘Pd-catalyzed gamma-arylation of gamma,delta-unsaturated O-carbamates via an unusual haptotropic rearrangement’, Chemical Science, 10(8), pp. 2331–2335. Available at: https://doi.org/10.1039/c8sc05058a.
Thesmar, Pierre and Baudoin, Olivier (2019) ‘Efficient and Divergent Total Synthesis of (-)-Epicoccin G and (-)-Rostratin A Enabled by Double C(sp; 3; )-H Activation’, Journal of the American Chemical Society, 141, pp. 15779–15783. Available at: https://doi.org/10.1021/jacs.9b09359.
Rocaboy, Ronan, Dailler, David and Baudoin, Olivier (2018) ‘A Four-Step Synthesis of (±)-γ-Lycorane via Pd0-Catalyzed Double C(sp2)-H/C(sp3)-H Arylation’, Organic Letters, 20(3), pp. 772–775. Available at: https://doi.org/10.1021/acs.orglett.7b03909.
Rocaboy, Ronan et al. (2018) ‘Domino Pd0-Catalyzed C(sp3)-H Arylation/Electrocyclic Reactions via Benzazetidine Intermediates’, Angewandte Chemie International Edition, 57(37), pp. 12131–12135. Available at: https://doi.org/10.1002/anie.201807097.
Yang, Lei, Neuburger, Markus and Baudoin, Olivier (2018) ‘Chiral Bifunctional Phosphine-Carboxylate Ligands for Palladium(0)-Catalyzed Enantioselective C-H Arylation’, Angewandte Chemie International Edition, 57(5), pp. 1394–1398. Available at: https://doi.org/10.1002/anie.201712061.
Zhang, Ke-Feng, Christoffel, Fadri and Baudoin, Olivier (2018) ‘Barbier-Negishi Coupling of Secondary Alkyl Bromides with Aryl and Alkenyl Triflates and Nonaflates’, Angewandte Chemie International Edition, 57(7), pp. 1982–1986. Available at: https://doi.org/10.1002/anie.201711990.
Baudoin, Olivier (2017) ‘Ring Construction by Palladium(0)-Catalyzed C(sp(3))-H Activation’, Accounts of Chemical Research, 50(4), pp. 1114–1123. Available at: https://doi.org/10.1021/acs.accounts.7b00099.
Dailler, David, Rocaboy, Ronan and Baudoin, Olivier (2017) ‘Synthesis of β-Lactams by Palladium(0)-Catalyzed C(sp3)−H Carbamoylation’, Angewandte Chemie International Edition, 56(25), pp. 7218–7222. Available at: https://doi.org/10.1002/anie.201703109.
Goutierre, Anne-Sophie et al. (2017) ‘Comparative Structural Analysis of Biarylphosphine Ligands in Arylpalladium Bromide and Malonate Complexes’, Organometallics, 36(1), pp. 129–135. Available at: https://doi.org/10.1021/acs.organomet.6b00535.
Holstein, Philipp M. et al. (2017) ‘Ferrocene derivatives of liquid chiral molecules allow assignment of absolute configuration by X-ray crystallography’, Tetrahedron: Asymmetry, 28(10), pp. 1321–1329. Available at: https://doi.org/10.1016/j.tetasy.2017.09.002.
Royal, Titouan, Baumgartner, Yann and Baudoin, Olivier (2017) ‘Enantioselective α-Arylation of O-Carbamates via Sparteine-Mediated Lithiation and Negishi Cross-Coupling’, Organic Letters, 19(1), pp. 166–169. Available at: https://doi.org/10.1021/acs.orglett.6b03472.
Yang, Lei et al. (2017) ‘Palladium(0)-catalyzed asymmetric C(sp3)-H arylation using a chiral binol-derived phosphate and an achiral ligand’, Chemical Science, 8(2), pp. 1344–1349. Available at: https://doi.org/10.1039/c6sc04006c.
Holstein, P.M. et al. (2016) ‘Synthesis of Strained γ-Lactams by Palladium(0)-Catalyzed C(sp3)-H Alkenylation and Application to Alkaloid Synthesis’, Angewandte Chemie - International Edition, 55(8), pp. 2805–2809. Available at: https://doi.org/10.1002/anie.201511457.
Baudoin, Olivier (2016) ‘Selectivity Control in the Palladium-catalyzed Cross-coupling of Alkyl Nucleophiles’, Chimia, 70(11), pp. 768–772. Available at: https://doi.org/10.2533/chimia.2016.768.
Dupuy, Stéphanie et al. (2016) ‘Terminal-Selective Functionalization of Alkyl Chains by Regioconvergent Cross-Coupling’, Angewandte Chemie International Edition, 55(47), pp. 14793–14797. Available at: https://doi.org/10.1002/anie.201608535.
Holstein, Philipp M. et al. (2016) ‘Synthesis of Strained γ-Lactams by Palladium(0)-Catalyzed C(sp3)−H Alkenylation and Application to Alkaloid Synthesis’, Angewandte Chemie, 128(8), pp. 2855–2859. Available at: https://doi.org/10.1002/ange.201511457.
Martin, Anthony, Vors, Jean-Pierre and Baudoin, Olivier (2016) ‘Synthesis of Conformationally Constrained Esters and Amines by Pd-Catalyzed α-Arylation of Hindered Substrates’, ACS Catalysis, 6(6), pp. 3941–3945. Available at: https://doi.org/10.1021/acscatal.6b00943.
Millet, A. and Baudoin, O. (2016) ‘Palladium-catalyzed β-Selective C(sp3)-H arylation of N-boc-piperidines’, Organic Syntheses, 92, pp. 76–90. Available at: https://doi.org/10.15227/orgsyn.92.0076.
Prieto, Alexis et al. (2016) ‘Electrophilic trifluoromethylation of carbonyl compounds and their nitrogen derivatives under copper catalysis’, Chemical Communications, 52(5), pp. 869–81. Available at: https://doi.org/10.1039/c5cc05954b.
Dailler, David, Danoun, Grégory and Baudoin, Olivier (2016) ‘Applications of Catalytic Organometallic C(sp3)-H Bond Functionalization’, in Dix-neuf, Pierre H.; Doucet, Henri (ed.) C-H bond activation and catalytic functionalization II. Cham: Springer International Publishing (Topics in Organometallic Chemistry), pp. 133–154. Available at: https://doi.org/10.1007/3418_2015_122.
Prieto, A. et al. (2015) ‘Copper-Catalyzed Trifluoromethylation of Aliphatic N-Arylhydrazones: A Concise Synthetic Entry to 2-Trifluoromethylindoles from Simple Aldehydes’, Advanced Synthesis and Catalysis, 357(13), pp. 2939–2943. Available at: https://doi.org/10.1002/adsc.201500237.
Holstein, P.M. et al. (2015) ‘Efficient Pd0-Catalyzed Asymmetric Activation of Primary and Secondary C-H Bonds Enabled by Modular Binepine Ligands and Carbonate Bases’, ACS Catalysis, 5(7), pp. 4300–4308. Available at: https://doi.org/10.1021/acscatal.5b00898.
Dailler, D. et al. (2015) ‘Divergent Synthesis of Aeruginosins Based on a C(sp3)£H Activation Strategy’, Chemistry - A European Journal, 21(26), pp. 9370–9379. Available at: https://doi.org/10.1002/chem.201501370.
Dailler, D., Danoun, G. and Baudoin, O. (2015) ‘A General and Scalable Synthesis of Aeruginosin Marine Natural Products Based on Two Strategic C(sp3)-H Activation Reactions’, Angewandte Chemie - International Edition, 54(16), pp. 4919–4922. Available at: https://doi.org/10.1002/anie.201500066.