[FG] Liechti Matthias

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Atila, C. et al. (2025) ‘Neurophysin I: A Reliable, Novel, and Robust Biomarker for Oxytocin’, European Journal of Endocrinology [Preprint]. Available at: https://doi.org/10.1093/ejendo/lvaf078.

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Gasser, P., Liechti, M.E. and Holze, F. (2025) ‘Treatment of neuropathic pain with repeated low-dose MDMA: a case report’, Frontiers in Psychiatry, 16. Available at: https://doi.org/10.3389/fpsyt.2025.1513022.

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Thomann, J. (2025) Bioanalysis and metabolic investigation of psychoactive substances. Doctoral Thesis.

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Straumann, I. et al. (2024) ‘Acute effects of R-MDMA, S-MDMA, and racemic MDMA in a randomized double-blind cross-over trial in healthy participants’, Neuropsychopharmacology, 50(2), pp. 362–371. Available at: https://doi.org/10.1038/s41386-024-01972-6.

Atila, Cihan et al. (2024) ‘Oxytocin and the Role of Fluid Restriction in MDMA-Induced Hyponatremia: A Secondary Analysis of 4 Randomized Clinical Trials’, JAMA network open, 7(11). Available at: https://doi.org/10.1001/jamanetworkopen.2024.45278.

Holze, F. et al. (2024) ‘Ketanserin exhibits dose- and concentration-proportional serotonin 2A receptor occupancy in healthy individuals: Relevance for psychedelic research’, European Neuropsychopharmacology, 88, pp. 43–48. Available at: https://doi.org/10.1016/j.euroneuro.2024.07.003.

Kamau, Yvonne et al. (2024) ‘Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial’, International Journal of Infectious Diseases, 148, p. 107236. Available at: https://doi.org/10.1016/j.ijid.2024.107236.

Calder, A.E. et al. (2024) ‘Naturalistic psychedelic therapy: The role of relaxation and subjective drug effects in antidepressant response’, Journal of Psychopharmacology, 38(10), pp. 873–886. Available at: https://doi.org/10.1177/02698811241278873.

Angerer, Verena et al. (2024) ‘Acute psychotropic, autonomic, and endocrine effects of 5,6-methylenedioxy-2-aminoindane (MDAI) compared with 3,4-methylenedioxymethamphetamine (MDMA) in human volunteers: A self-administration study’, Drug Testing and Analysis, 16(9), pp. 1002–1011. Available at: https://doi.org/10.1002/dta.3622.

Holze, F. et al. (2024) ‘LSD-assisted therapy in patients with anxiety: open-label prospective 12-month follow-up’, British Journal of Psychiatry, 225(3), pp. 362–370. Available at: https://doi.org/10.1192/bjp.2024.99.

Arias, H.R. et al. (2024) ‘Non-hallucinogenic compounds derived from iboga alkaloids alleviate neuropathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation’, Biomedicine and Pharmacotherapy, 177. Available at: https://doi.org/10.1016/j.biopha.2024.116867.

Stocker, K. and Liechti, M.E. (2024) ‘Methylenedioxymethamphetamine is a connectogen with empathogenic, entactogenic, and still further connective properties: It is time to reconcile “the great entactogen—empathogen debate”’, Journal of Psychopharmacology, 38(8), pp. 685–689. Available at: https://doi.org/10.1177/02698811241265352.

Müller-Durovic, Bojana et al. (2024) ‘A metabolic dependency of EBV can be targeted to hinder B cell transformation’, Science (New York, N.Y.), 385(6704). Available at: https://doi.org/10.1126/science.adk4898.

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Anliker‐Ort, Marion et al. (2024) ‘Pharmacokinetics-Based Pediatric Dose Evaluation and Optimization Using Saliva – A Case Study’, Journal of Clinical Pharmacology, 64(7), pp. 810–819. Available at: https://doi.org/10.1002/jcph.2428.

Walz, Annabelle et al. (2024) ‘In vivo antimalarial efficacy of Artemisia afra powder suspensions’, Phytomedicine, 129. Available at: https://doi.org/10.1016/j.phymed.2024.155644.

Dao, Kim et al. (2024) ‘Novel Patient‐Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use’, The Journal of Clinical Pharmacology. 30.05.2024, 64(10), pp. 1295–1303. Available at: https://doi.org/10.1002/jcph.2462.

Blukacz, Lauriane et al. (2024) ‘Inhibition of the transmembrane transporter ABCB1 overcomes resistance to doxorubicin in patient-derived organoid models of HCC’, Hepatology Communications, 8(5). Available at: https://doi.org/10.1097/HC9.0000000000000437.

Atila, Cihan et al. (2024) ‘Psychopathological characteristics in patients with arginine vasopressin deficiency (central diabetes insipidus) and primary polydipsia compared to healthy controls’, European Journal of Endocrinology, 190(5), pp. 354–362. Available at: https://doi.org/10.1093/ejendo/lvae040.

Luethi, Dino et al. (2024) ‘Derivatization-free determination of chiral plasma pharmacokinetics of MDMA and its enantiomers’, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1238. Available at: https://doi.org/10.1016/j.jchromb.2024.124123.

Thomann, Jan et al. (2024) ‘Development and validation of an LC-MS/MS method for quantifying diamorphine and its major metabolites 6-monoacetylmorphine, morphine, morphine-3-glucuronide, and morphine-6-glucuronide in human plasma’, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1237, p. 124104. Available at: https://doi.org/10.1016/j.jchromb.2024.124104.

Thomann, Jan et al. (2024) ‘Development and validation of an LC-MS/MS method for quantifying diamorphine and its major metabolites 6-monoacetylmorphine, morphine, morphine-3-glucuronide, and morphine-6-glucuronide in human plasma’, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1237. Available at: https://doi.org/10.1016/j.jchromb.2024.124104.

Arias, Hugo R. et al. (2024) ‘The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative- and anxiolytic-like activity in mice by a mechanism involving 5-HT2A receptor activation’, European Journal of Pharmacology, 966. Available at: https://doi.org/10.1016/j.ejphar.2024.176329.

Abegg, Vanessa Fabienne et al. (2024) ‘Mechanisms of hepatocellular toxicity associated with the components of St. John’s Wort extract hypericin and hyperforin in HepG2 and HepaRG cells’, Toxicology Letters, 393, pp. 1–13. Available at: https://doi.org/10.1016/j.toxlet.2024.01.008.

Atila, C. et al. (2024) ‘Oxytocin, Not Vasopressin, Mediates High Incidence of MDMA-Induced Hyponatremia - A Complication Preventable by Fluid Restriction’. Elsevier BV. Available at: https://doi.org/10.2139/ssrn.4819307.

Holze, Friederike et al. (2024) ‘Pharmacokinetics, pharmacodynamics and urinary recovery of oral lysergic acid diethylamide administration in healthy participants’, British Journal of Clinical Pharmacology, 90(1), pp. 200–208. Available at: https://doi.org/10.1111/bcp.15887.

Holze, F., Liechti, M.E. and Müller, F. (2024) ‘Pharmacological Properties of Psychedelics with a Special Focus on Potential Harms’, in Current Topics in Behavioral Neurosciences. Berlin, Heidelberg: Springer Berlin Heidelberg (Current Topics in Behavioral Neurosciences). Available at: https://doi.org/10.1007/7854_2024_510.

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Liechti, Matthias E. (2024) ‘Psychedelics as medication?’, Revue Medicale Suisse, 20, pp. 118–119. Available at: https://doi.org/10.53738/revmed.2024.20.858.118.

Straumann, I. et al. (2024) ‘Safety pharmacology of acute psilocybin administration in healthy participants’, Neuroscience Applied, 3, p. 104060. Available at: https://doi.org/10.1016/j.nsa.2024.104060.

Thomann, Jan et al. (2024) ‘In vitro and in vivo metabolism of psilocybin’s active metabolite psilocin’, Frontiers in Pharmacology, 15. Available at: https://doi.org/10.3389/fphar.2024.1391689.

Thomann, Jan et al. (2024) ‘In vitro and in vivo metabolism of psilocybin’s active metabolite psilocin’, Frontiers in Pharmacology, 15. Available at: https://doi.org/10.3389/fphar.2024.1391689.

Waters, M.L. et al. (2024) ‘Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020’, Clinical Toxicology, 62(6), pp. 378–384. Available at: https://doi.org/10.1080/15563650.2024.2346125.

Waters, Mitchell L. et al. (2024) ‘Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020’, Clinical Toxicology, 62(6), pp. 378–384. Available at: https://doi.org/10.1080/15563650.2024.2346125.

Vallersnes, O.M. et al. (2023) ‘Self-discharge during treatment for acute recreational drug toxicity: an observational study from emergency departments in seven European countries’, International Journal of Emergency Medicine, 16(1). Available at: https://doi.org/10.1186/s12245-023-00566-1.

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Ley, Laura et al. (2023) ‘Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants’, Neuropsychopharmacology, 48(11), pp. 1659–1667. Available at: https://doi.org/10.1038/s41386-023-01607-2.

Ley, Laura et al. (2023) ‘Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants’, Neuropsychopharmacology, 48(11), pp. 1659–1667. Available at: https://doi.org/10.1038/s41386-023-01607-2.

Noseda, Roberta et al. (2023) ‘Determinants of Admission to Critical Care Following Acute Recreational Drug Toxicity: A Euro-DEN Plus Study’, Journal of Clinical Medicine, 12(18). Available at: https://doi.org/10.3390/jcm12185970.

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Reissmann, Steffen et al. (2023) ‘Case report: Maintaining altered states of consciousness over repeated ketamine infusions may be key to facilitate long-lasting antidepressant effects: some initial lessons from a personalized-dosing single-case study’, Frontiers in Psychiatry, 14. Available at: https://doi.org/10.3389/fpsyt.2023.1197697.

Rudin, Deborah et al. (2023) ‘Classic psychedelics do not affect T cell and monocyte immune responses’, Frontiers in Psychiatry, 14, p. 1042440. Available at: https://doi.org/10.3389/fpsyt.2023.1042440.

Luethi, Dino et al. (2022) ‘Liquid chromatography–tandem mass spectrometry method for the bioanalysis of N,N-dimethyltryptamine (DMT) and its metabolites DMT-N-oxide and indole-3-acetic acid in human plasma’, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1213. Available at: https://doi.org/10.1016/j.jchromb.2022.123534.

Luethi, Dino et al. (2022) ‘Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux’, Communications Biology, 5(1). Available at: https://doi.org/10.1038/s42003-022-04210-1.

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Luethi D. and Liechti M.E. (2022) ‘Correction to: Designer drugs: mechanism of action and adverse effects (Archives of Toxicology, (2020), 94, 4, (1085-1133), 10.1007/s00204-020-02693-7)’, Archives of Toxicology, 96(5), p. 1489. Available at: https://doi.org/10.1007/s00204-022-03244-y.

Rudin, Deborah et al. (2022) ‘(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice’, Neuropsychopharmacology, 47(4), pp. 914–923. Available at: https://doi.org/10.1038/s41386-021-01221-0.

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Becker, Anna M. et al. (2022) ‘Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects’, Clinical Pharmacology & Therapeutics, 111(4), pp. 886–895. Available at: https://doi.org/10.1002/cpt.2487.

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