[FG] Liechti Matthias

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Klaiber, A. et al. (2024) ‘Acute dose-dependent effects of mescaline in a double-blind placebo-controlled study in healthy subjects’, Translational Psychiatry, 14(1). Available at: https://doi.org/10.1038/s41398-024-03116-2.

Calder, A.E. et al. (2024) ‘Naturalistic psychedelic therapy: The role of relaxation and subjective drug effects in antidepressant response’, Journal of Psychopharmacology [Preprint]. Available at: https://doi.org/10.1177/02698811241278873.

Avram, M. et al. (2024) ‘Large-scale brain connectivity changes following the administration of lysergic acid diethylamide, d-amphetamine, and 3,4-methylenedioxyamphetamine’, Molecular Psychiatry [Preprint]. Available at: https://doi.org/10.1038/s41380-024-02734-y.

Straumann, I. et al. (2024) ‘Acute effects of R-MDMA, S-MDMA, and racemic MDMA in a randomized double-blind cross-over trial in healthy participants’, Neuropsychopharmacology [Preprint]. Available at: https://doi.org/10.1038/s41386-024-01972-6.

Arias, H.R. et al. (2024) ‘Non-hallucinogenic compounds derived from iboga alkaloids alleviate neuropathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation’, Biomedicine and Pharmacotherapy, 177. Available at: https://doi.org/10.1016/j.biopha.2024.116867.

Stocker, K. and Liechti, M.E. (2024) ‘Methylenedioxymethamphetamine is a connectogen with empathogenic, entactogenic, and still further connective properties: It is time to reconcile “the great entactogen—empathogen debate”’, Journal of Psychopharmacology, 38(8), pp. 685–689. Available at: https://doi.org/10.1177/02698811241265352.

Holze, F. et al. (2024) ‘LSD-assisted therapy in patients with anxiety: open-label prospective 12-month follow-up’, The British Journal of Psychiatry, pp. 1–9. Available at: https://doi.org/10.1192/bjp.2024.99.

Hutten, N.R.P.W. et al. (2024) ‘Inter-individual variability in neural response to low doses of LSD’, Translational Psychiatry, 14(1). Available at: https://doi.org/10.1038/s41398-024-03013-8.

Müller-Durovic, Bojana et al. (2024) ‘A metabolic dependency of EBV can be targeted to hinder B cell transformation’, Science, 385(6704). Available at: https://doi.org/10.1126/science.adk4898.

Anliker‐Ort, Marion et al. (2024) ‘Pharmacokinetics‐Based Pediatric Dose Evaluation and Optimization Using Saliva – A Case Study’, The Journal of Clinical Pharmacology, 64(7), pp. 810–819. Available at: https://doi.org/10.1002/jcph.2428.

Waters, Mitchell L. et al. (2024) ‘Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020’, Clinical Toxicology, 62(6), pp. 378–384. Available at: https://doi.org/10.1080/15563650.2024.2346125.

Dao, Kim et al. (2024) ‘Novel Patient‐Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use’, The Journal of Clinical Pharmacology. 30.05.2024, 64(10), pp. 1295–1303. Available at: https://doi.org/10.1002/jcph.2462.

Blukacz, L. et al. (2024) ‘Inhibition of the transmembrane transporter ABCB1 overcomes resistance to doxorubicin in patient-derived organoid models of HCC’, Hepatology Communications, 8(5). Available at: https://doi.org/10.1097/hc9.0000000000000437.

Thomann, Jan et al. (2024) ‘In vitro and in vivo metabolism of psilocybin’s active metabolite psilocin’, Frontiers in Pharmacology, 15. Available at: https://doi.org/10.3389/fphar.2024.1391689.

Thomann, Jan et al. (2024) ‘Development and validation of an LC-MS/MS method for quantifying diamorphine and its major metabolites 6-monoacetylmorphine, morphine, morphine-3-glucuronide, and morphine-6-glucuronide in human plasma’, Journal of Chromatography B, 1237, p. 124104. Available at: https://doi.org/10.1016/j.jchromb.2024.124104.

Abegg, Vanessa Fabienne et al. (2024) ‘Mechanisms of hepatocellular toxicity associated with the components of St. John’s Wort extract hypericin and hyperforin in HepG2 and HepaRG cells’, Toxicology Letters, 393, pp. 1–13. Available at: https://doi.org/10.1016/j.toxlet.2024.01.008.

Anliker-Ort, Marion et al. (2024) ‘Pharmacokinetics-Based Pediatric Dose Evaluation and Optimization Using Saliva – A Case Study’, Journal of Clinical Pharmacology, 64, pp. 810–819. Available at: https://doi.org/10.1002/jcph.2428.

Arias, Hugo R. et al. (2024) ‘The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative- and anxiolytic-like activity in mice by a mechanism involving 5-HT 2A receptor activation’, European Journal of Pharmacology, 966. Available at: https://doi.org/10.1016/j.ejphar.2024.176329.

Atila, Cihan et al. (2024) ‘Psychopathological characteristics in patients with arginine vasopressin deficiency (central diabetes insipidus) and primary polydipsia compared to healthy controls’, European Journal of Endocrinology, 190, pp. 354–362. Available at: https://doi.org/10.1093/ejendo/lvae040.

Atila, C. et al. (2024) ‘Oxytocin, Not Vasopressin, Mediates High Incidence of MDMA-Induced Hyponatremia - A Complication Preventable by Fluid Restriction’. Elsevier BV. Available at: https://doi.org/10.2139/ssrn.4819307.

Holze, F., Liechti, M.E. and Müller, F. (2024) ‘Pharmacological Properties of Psychedelics with a Special Focus on Potential Harms’, in Current Topics in Behavioral Neurosciences. Berlin, Heidelberg: Springer Berlin Heidelberg (Current Topics in Behavioral Neurosciences). Available at: https://doi.org/10.1007/7854_2024_510.

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Liechti, Matthias E. (2024) ‘Psychedelics as medication?’, Revue Medicale Suisse, 20, pp. 118–119. Available at: https://doi.org/10.53738/revmed.2024.20.858.118.

Luethi, Dino et al. (2024) ‘Derivatization-free determination of chiral plasma pharmacokinetics of MDMA and its enantiomers’, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1238. Available at: https://doi.org/10.1016/j.jchromb.2024.124123.

Straumann, I. et al. (2024) ‘Safety pharmacology of acute psilocybin administration in healthy participants’, Neuroscience Applied, 3, p. 104060. Available at: https://doi.org/10.1016/j.nsa.2024.104060.

Thomann, Jan et al. (2024) ‘In vitro and in vivo metabolism of psilocybin’s active metabolite psilocin’, Frontiers in Pharmacology, 15. Available at: https://doi.org/10.3389/fphar.2024.1391689.

Thomann, Jan et al. (2024) ‘Development and validation of an LC-MS/MS method for quantifying diamorphine and its major metabolites 6-monoacetylmorphine, morphine, morphine-3-glucuronide, and morphine-6-glucuronide in human plasma’, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1237. Available at: https://doi.org/10.1016/j.jchromb.2024.124104.

Waters, M.L. et al. (2024) ‘Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020’, Clinical Toxicology, 62(6), pp. 378–384. Available at: https://doi.org/10.1080/15563650.2024.2346125.

Ley, Laura et al. (2023) ‘Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants’, Neuropsychopharmacology, 48(11), pp. 1659–1667. Available at: https://doi.org/10.1038/s41386-023-01607-2.

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Angerer, V. et al. (2023) ‘Acute psychotropic, autonomic, and endocrine effects of 5,6-methylenedioxy-2-aminoindane (MDAI) compared with 3,4-methylenedioxymethamphetamine (MDMA) in human volunteers: A self-administration study’, Drug Testing and Analysis, null. Available at: https://doi.org/10.1002/dta.3622.

Halberstadt, Adam L. et al. (2023) ‘Use of the head-twitch response to investigate the structure–activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines’, Psychopharmacology, 240, pp. 115–126. Available at: https://doi.org/10.1007/s00213-022-06279-2.

Ley, Laura et al. (2023) ‘Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants’, Neuropsychopharmacology, 48, pp. 1659–1667. Available at: https://doi.org/10.1038/s41386-023-01607-2.

Miró, Òscar et al. (2023) ‘Severity of emergency department presentations due to acute drug toxicity in Europe: A longitudinal analysis over a 6-year period (2014-2019) stratified by sex’, European Journal of Emergency Medicine, 30, pp. 21–31. Available at: https://doi.org/10.1097/mej.0000000000000978.

Noseda, Roberta et al. (2023) ‘Determinants of Admission to Critical Care Following Acute Recreational Drug Toxicity: A Euro-DEN Plus Study’, Journal of Clinical Medicine, 12. Available at: https://doi.org/10.3390/jcm12185970.

Reissmann, Steffen et al. (2023) ‘Case report: Maintaining altered states of consciousness over repeated ketamine infusions may be key to facilitate long-lasting antidepressant effects: some initial lessons from a personalized-dosing single-case study’, Frontiers in Psychiatry, 14. Available at: https://doi.org/10.3389/fpsyt.2023.1197697.

Rudin, Deborah et al. (2023) ‘Classic psychedelics do not affect T cell and monocyte immune responses’, Frontiers in Psychiatry, 14, p. 1042440. Available at: https://doi.org/10.3389/fpsyt.2023.1042440.

Vallersnes, O.M. et al. (2023) ‘Self-discharge during treatment for acute recreational drug toxicity: an observational study from emergency departments in seven European countries’, International Journal of Emergency Medicine, 16. Available at: https://doi.org/10.1186/s12245-023-00566-1.

Vogt, Severin B. et al. (2023) ‘Acute effects of intravenous DMT in a randomized placebo-controlled study in healthy participants’, Translational Psychiatry, 13. Available at: https://doi.org/10.1038/s41398-023-02477-4.

Luethi, Dino et al. (2022) ‘Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux’, Communications Biology, 5(1). Available at: https://doi.org/10.1038/s42003-022-04210-1.

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Stocker K. et al. (2022) ‘Buddhist-like opposite diminishing and non-judging during ketamine infusion are associated with antidepressant response: an open-label personalized-dosing study’, Frontiers in Pharmacology, 13. Available at: https://doi.org/10.3389/fphar.2022.916641.

Kolaczynska K.E. et al. (2022) ‘Pharmacological characterization of 3,4-methylenedioxamphetamine (MDA) analogs and two amphetamine-based compounds: N,α-DEPEA and DPIA’, European Neuropsychopharmacology, 59, pp. 9–22. Available at: https://doi.org/10.1016/j.euroneuro.2022.03.006.

Luethi D. and Liechti M.E. (2022) ‘Correction to: Designer drugs: mechanism of action and adverse effects (Archives of Toxicology, (2020), 94, 4, (1085-1133), 10.1007/s00204-020-02693-7)’, Archives of Toxicology, 96(5), p. 1489. Available at: https://doi.org/10.1007/s00204-022-03244-y.

Rudin, Deborah et al. (2022) ‘(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice’, Neuropsychopharmacology, 47(4), pp. 914–923. Available at: https://doi.org/10.1038/s41386-021-01221-0.

Rudin D et al. (2022) ‘(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice.’, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 47(4), pp. 914–923. Available at: https://doi.org/10.1038/s41386-021-01221-0.

Kleer JS et al. (2022) ‘Epitope-Specific Anti-C1q Autoantibodies in Systemic Lupus Erythematosus’, Frontiers in Immunology, 12, p. 761395. Available at: https://doi.org/10.3389/fimmu.2021.761395.

Becker, Anna M. et al. (2022) ‘Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects’, Clinical Pharmacology & Therapeutics, 111(4), pp. 886–895. Available at: https://doi.org/10.1002/cpt.2487.

Crulli, B. et al. (2022) ‘Novel psychoactive substances-related presentations to the emergency departments of the European drug emergencies network plus (Euro-DEN plus) over the six-year period 2014–2019’, Clinical Toxicology, 60, pp. 1318–1327. Available at: https://doi.org/10.1080/15563650.2022.2137524.

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Holze, Friederike et al. (2022) ‘Safety pharmacology of acute LSD administration in healthy subjects’, Psychopharmacology, 239(6), pp. 1893–1905. Available at: https://doi.org/10.1007/s00213-021-05978-6.

Holze, Friederike et al. (2022) ‘Correction to: Safety pharmacology of acute LSD administration in healthy subjects’, Psychopharmacology, 239(2), p. 661. Available at: https://doi.org/10.1007/s00213-021-05988-4.

Holze, Friederike et al. (2022) ‘Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects’, Neuropsychopharmacology, 47(6), pp. 1180–1187. Available at: https://doi.org/10.1038/s41386-022-01297-2.

Kolaczynska, Karolina E. et al. (2022) ‘Receptor Interaction Profiles of 4-Alkoxy-3,5-Dimethoxy-Phenethylamines (Mescaline Derivatives) and Related Amphetamines’, Frontiers in Pharmacology, 12, p. 794254. Available at: https://doi.org/10.3389/fphar.2021.794254.

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Luethi, Dino et al. (2022) ‘Liquid chromatography–tandem mass spectrometry method for the bioanalysis of N,N-dimethyltryptamine (DMT) and its metabolites DMT-N-oxide and indole-3-acetic acid in human plasma’, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1213. Available at: https://doi.org/10.1016/j.jchromb.2022.123534.

Müller, Felix et al. (2022) ‘Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants’, Psychopharmacology, 239(6), pp. 1933–1943. Available at: https://doi.org/10.1007/s00213-022-06066-z.

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Kolaczynska KE, Liechti ME and Duthaler U (2021) ‘Development and validation of an LC-MS/MS method for the bioanalysis of psilocybin’s main metabolites, psilocin and 4-hydroxyindole-3-acetic acid, in human plasma’, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1164, p. 122486. Available at: https://doi.org/10.1016/j.jchromb.2020.122486.

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Dolder, Patrick C., Liechti, Matthias E. and Rentsch, Katharina M. (2021) ‘Development and validation of a rapid turboflow LC-MS/MS method for the quantification of LSD and 2-oxo-3-hydroxy LSD in serum and urine samples of emergency toxicological cases’, Analytical and Bioanalytical Chemistry, 407, pp. 1577–1584. Available at: https://doi.org/10.1007/s00216-014-8388-1.

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