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Preclinical in vivo proof of mechanism study of selective mTORC1 inhibitors

Research Project
 | 
01.07.2022
 - 30.06.2024

Laufzeit 01.04.2022-31.01.2024 Increased activity of mammalian target of rapamycin complex 1(mTORC1) is linked to multiple disorders. We identified ten small compounds that selectively and efficiently inhibit mTORC1 in vitro with an innovative mode of action. We now aim to achieve precinlincal proof of mechanism in mice.

Funding

Preclinical in vivo proof of mechanism study of selective mTORC1 inhibitors

Innosuisse Projekt (GrantsTool), 07.2022-06.2024 (24)
PI : Hall, Michael N.,Maier, Timm.

Members (2)

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Michael N. Hall

Principal Investigator
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Timm Maier

Principal Investigator