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X-Fold StereoGen: Catalyst Control over X-Fold Stereogenicity

Research Project
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01.02.2021
 - 31.01.2026

Stereoisomers are molecular entities with identical atomic connections existing in separate forms due to the different arrangements of their atoms in space. Most stereogenic units encode two configurations, describing distinct three-dimensional molecular structures. These strongly impact molecular properties, which prompts preparative methods with control over configuration, ideally using catalysts that enable selective transformations. The catalysts differentiate competing reaction pathways towards the desired stereoisomer and remain intact throughout the process. The aim of the EU-funded X-Fold StereoGen project is now to catalytically control stereogenic units that encode more than two configurations. Besides the larger stereochemical space addressable by stereoselective synthesis, the conceptual interconnection between higher-order stereogenicity and conformational space is endeavored.

Funding

X-Fold StereoGen: Catalyst Control over X-Fold Stereogenicity

Horizon 2020 ERC (GrantsTool), 02.2021-01.2026 (60)
PI : Sparr, Christof.

Members (1)

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Christof Sparr

Principal Investigator