Real-time Evolutionary Tracking for Pathogen Surveillance and Epidemiological Investigation
Research Project
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01.04.2017
- 31.03.2020
Genome sequences of viral pathogens have the capacity to provide valuable insight into epidemic transmission patterns and viral evolution. But to inform public health interventions in acute public health crises, genomic data has to be analyzed and results diseminated in near real-time. The goal of this project is to promote open sharing of viral genomic data and harness this data to make epidemiologically actionable inferences. For this project, we are developing an integrated framework for real-time molecular epidemiology and evolutionary analysis of emerging epidemics, such as Ebola virus, MERS-CoV and Zika virus. This framework includes an online visualization platform deployed to the website nextstrain.org that is continually updated as new data becomes available. This platform pools data from across research groups thereby synthesizing disparate datasets and serves to promote open science in the face of public health crises. All source code is publicly available at github.com/nextstrain.