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Dissecting the formation, dynamics and interaction of coiled doils at atomic detail: Intermediate filaments, the stalk domain of a heterodimeric kinesin and the unusual leucine zipper of the Nek2 kinase

Research Project
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01.04.2003
 - 31.03.2009

bonus-of-excellence, keratins, vimentin, Protein coiled coils, nuclear lamins, protein oligomerization, intermediate filaments

Publications

Kapinos, Larisa E et al. (2010) ‘Characterization of the head-to-tail overlap complexes formed by human lamin A, B1 and B2 ‘half-minilamin’ dimers’, Journal of molecular biology, 396(3), pp. 719–31. Available at: https://doi.org/10.1016/j.jmb.2009.12.001.

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Nicolet, Stefan et al. (2010) ‘Atomic structure of vimentin coil 2’, Journal of structural biology, 170(2), pp. 369–76. Available at: https://doi.org/10.1016/j.jsb.2010.02.012.

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Bär, Harald et al. (2009) ‘Interference of amino-terminal desmin fragments with desmin filament formation’, Cell motility and the cytoskeleton, 66(11), pp. 986–99. Available at: https://doi.org/10.1002/cm.20396.

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Ben-Harush, Kfir et al. (2009) ‘The supramolecular organization of the C. elegans nuclear lamin filament’, Journal of molecular biology, 386(5), pp. 1392–402. Available at: https://doi.org/10.1016/j.jmb.2008.12.024.

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Georgakopoulou, Sofia et al. (2009) ‘Near-UV circular dichroism reveals structural transitions of vimentin subunits during intermediate filament assembly’, Journal of molecular biology, 386(2), pp. 544–53. Available at: https://doi.org/10.1016/j.jmb.2008.12.053.

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Meier, Markus et al. (2009) ‘Vimentin Coil 1A : a molecular switch involved in the initiation of filament elongation’, Journal of molecular biology, 390(2), pp. 245–61. Available at: https://doi.org/10.1016/j.jmb.2009.04.067.

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Members (2)

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Ueli Aebi

Principal Investigator
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Peter Burkhard

Co-Investigator