HypoGly – Incidence and Risk Factors of Hypoglycaemia in Critically Ill Patients

Retrospective cohort of all adult ICU admissions at USB Basel between January 2019 and January 2026 (approximately 22,510 admissions). Primary outcome: incidence of hypoglycaemia (BG <3.9 mmol/L), two-tier severity classification (Level 1: 3.0–3.8; Level 2: <3.0). Risk-factor analysis (baseline comorbidity, severity scores, 72-h treatment exposures including insulin, total calories, corticosteroids), Cox PH for 30/90-day mortality with hypoglycaemia as time-dependent covariate, Fine–Gray competing-risk model for length of stay. GLMM with each glucose measurement as the unit of analysis to address ascertainment bias.