Thrombolysis in Ischemic Stroke Patients (TRISP): a multicentre research collaboration
Research Project | 01.01.2010
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01.01.2010
TRISP is an open, investigator-driven collaborative research initiative of European stroke centres with expertise in treatment with revascularisation therapies and maintenance of hospital-based registries. All participating centres made a commitment to prospectively collect data on consecutive patients with stroke treated with IVT using standardised definitions of variables and outcomes, to assure accuracy and completeness of the data and to adapt their local databases to answer novel research questions. TRISP aims to address clinically relevant questions about safety and outcomes of intravenous thrombolysis (IVT) and endovascular thrombectomy. The findings can provide observational information on treatment of patients derived from everyday clinical practice.
Publications
Seystahl K et al. (2023) ‘IV Thrombolysis With or Without Endovascular Treatment for Suspected Ischemic Stroke in Patients With Intracranial Tumors.’, Neurology, 101(12), pp. e1241–e1255. Available at: https://doi.org/10.1212/wnl.0000000000207624.
Seystahl K et al. (2023) ‘IV Thrombolysis With or Without Endovascular Treatment for Suspected Ischemic Stroke in Patients With Intracranial Tumors.’, Neurology, 101(12), pp. e1241–e1255. Available at: https://doi.org/10.1212/wnl.0000000000207624.
Baumgartner P et al. (2023) ‘Safety and effectiveness of IV Thrombolysis in retinal artery occlusion: A multicenter retrospective cohort study.’, European stroke journal, p. 23969873231185895. Available at: https://doi.org/10.1177/23969873231185895.
Baumgartner P et al. (2023) ‘Safety and effectiveness of IV Thrombolysis in retinal artery occlusion: A multicenter retrospective cohort study.’, European stroke journal, p. 23969873231185895. Available at: https://doi.org/10.1177/23969873231185895.
Altersberger, Valerian L. et al. (2023) ‘Intravenous Thrombolysis 4.5–9 Hours After Stroke Onset: A Cohort Study from the TRISP Collaboration’, Annals of Neurology. 28.04.2023, 94(2), pp. 309–320. Available at: https://doi.org/10.1002/ana.26669.
Altersberger, Valerian L. et al. (2023) ‘Intravenous Thrombolysis 4.5–9 Hours After Stroke Onset: A Cohort Study from the TRISP Collaboration’, Annals of Neurology. 28.04.2023, 94(2), pp. 309–320. Available at: https://doi.org/10.1002/ana.26669.
Meinel, Thomas R. et al. (2023) ‘Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants’, JAMA Neurology, 80, pp. 233–243. Available at: https://doi.org/10.1001/jamaneurol.2022.4782.
Meinel, Thomas R. et al. (2023) ‘Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants’, JAMA Neurology, 80, pp. 233–243. Available at: https://doi.org/10.1001/jamaneurol.2022.4782.
Altersberger VL et al. (2022) ‘Thrombolysis in stroke patients with elevated inflammatory markers.’, Journal of neurology, 269(10), pp. 5405–5419. Available at: https://doi.org/10.1007/s00415-022-11173-0.
Altersberger VL et al. (2022) ‘Thrombolysis in stroke patients with elevated inflammatory markers.’, Journal of neurology, 269(10), pp. 5405–5419. Available at: https://doi.org/10.1007/s00415-022-11173-0.
Altersberger, Valerian L. et al. (2022) ‘Intravenous Thrombolysis in Patients With Ischemic Stroke Aged ≥90 Years: A Cohort Study From the TRISP Collaboration’, Stroke, 53, pp. 3557–3563. Available at: https://doi.org/10.1161/strokeaha.122.039426.
Altersberger, Valerian L. et al. (2022) ‘Intravenous Thrombolysis in Patients With Ischemic Stroke Aged ≥90 Years: A Cohort Study From the TRISP Collaboration’, Stroke, 53, pp. 3557–3563. Available at: https://doi.org/10.1161/strokeaha.122.039426.
Altersberger, Valerian L. et al. (2021) ‘Maintenance of Acute Stroke Care Service During the COVID-19 Pandemic Lockdown.’, Stroke. 01.04.2021, 52(5), pp. 1693–1701. Available at: https://doi.org/10.1161/strokeaha.120.032176.
Altersberger, Valerian L. et al. (2021) ‘Maintenance of Acute Stroke Care Service During the COVID-19 Pandemic Lockdown.’, Stroke. 01.04.2021, 52(5), pp. 1693–1701. Available at: https://doi.org/10.1161/strokeaha.120.032176.
Altersberger, V.L. et al. (2020) ‘Effect of haemoglobin levels on outcome in intravenous thrombolysis-treated stroke patients’, European Stroke Journal, 5(2), pp. 138–147. Available at: https://doi.org/10.1177/2396987319889468.
Altersberger, V.L. et al. (2020) ‘Effect of haemoglobin levels on outcome in intravenous thrombolysis-treated stroke patients’, European Stroke Journal, 5(2), pp. 138–147. Available at: https://doi.org/10.1177/2396987319889468.
Altersberger, Valerian L. et al. (2020) ‘Prior Dual Antiplatelet Therapy and Thrombolysis in Acute Stroke’, Annals of Neurology. 19.07.2020, 88(4), pp. 857–859. Available at: https://doi.org/10.1002/ana.25850.
Altersberger, Valerian L. et al. (2020) ‘Prior Dual Antiplatelet Therapy and Thrombolysis in Acute Stroke’, Annals of Neurology. 19.07.2020, 88(4), pp. 857–859. Available at: https://doi.org/10.1002/ana.25850.
Westphal, Laura P. et al. (2020) ‘Association of prestroke metformin use, stroke severity, and thrombolysis outcome’, Neurology, 95(4), pp. e362–e373. Available at: https://doi.org/10.1212/wnl.0000000000009951.
Westphal, Laura P. et al. (2020) ‘Association of prestroke metformin use, stroke severity, and thrombolysis outcome’, Neurology, 95(4), pp. e362–e373. Available at: https://doi.org/10.1212/wnl.0000000000009951.
Polymeris AA et al. (2019) ‘Intravenous thrombolysis for suspected ischemic stroke with seizure at onset.’, Annals of neurology, 86(5), pp. 770–779. Available at: https://doi.org/10.1002/ana.25582.
Polymeris AA et al. (2019) ‘Intravenous thrombolysis for suspected ischemic stroke with seizure at onset.’, Annals of neurology, 86(5), pp. 770–779. Available at: https://doi.org/10.1002/ana.25582.
Zonneveld TP et al. (2018) ‘Non-office-hours admission affects intravenous thrombolysis treatment times and clinical outcome.’, 89(9). Available at: https://doi.org/10.1136/jnnp-2017-316791.
Zonneveld TP et al. (2018) ‘Non-office-hours admission affects intravenous thrombolysis treatment times and clinical outcome.’, 89(9). Available at: https://doi.org/10.1136/jnnp-2017-316791.
Gensicke H et al. (2018) ‘Intravenous thrombolysis and platelet count.’, Neurology, 90(8), pp. e690–e697. Available at: https://doi.org/10.1212/wnl.0000000000004982.
Gensicke H et al. (2018) ‘Intravenous thrombolysis and platelet count.’, Neurology, 90(8), pp. e690–e697. Available at: https://doi.org/10.1212/wnl.0000000000004982.
Scheitz, Jan F. et al. (2018) ‘Cohort profile: Thrombolysis in Ischemic Stroke Patients (TRISP): a multicentre research collaboration’, BMJ Open, 8. Available at: https://doi.org/10.1136/bmjopen-2018-023265.
Scheitz, Jan F. et al. (2018) ‘Cohort profile: Thrombolysis in Ischemic Stroke Patients (TRISP): a multicentre research collaboration’, BMJ Open, 8. Available at: https://doi.org/10.1136/bmjopen-2018-023265.
Scheitz JF et al. (2017) ‘Intracerebral Hemorrhage and Outcome After Thrombolysis in Stroke Patients Using Selective Serotonin-Reuptake Inhibitors.’, Stroke, 48(12), pp. 3239–3244. Available at: https://doi.org/10.1161/strokeaha.117.018377.
Scheitz JF et al. (2017) ‘Intracerebral Hemorrhage and Outcome After Thrombolysis in Stroke Patients Using Selective Serotonin-Reuptake Inhibitors.’, Stroke, 48(12), pp. 3239–3244. Available at: https://doi.org/10.1161/strokeaha.117.018377.
Spaander FH et al. (2017) ‘Sex Differences and Functional Outcome After Intravenous Thrombolysis.’, Stroke, 48(3), pp. 699–703. Available at: https://doi.org/10.1161/strokeaha.116.014739.
Spaander FH et al. (2017) ‘Sex Differences and Functional Outcome After Intravenous Thrombolysis.’, Stroke, 48(3), pp. 699–703. Available at: https://doi.org/10.1161/strokeaha.116.014739.
Gensicke H et al. (2017) ‘Prognostic significance of proteinuria in stroke patients treated with intravenous thrombolysis.’, European journal of neurology, 24(2), pp. 262–269. Available at: https://doi.org/10.1111/ene.13179.
Gensicke H et al. (2017) ‘Prognostic significance of proteinuria in stroke patients treated with intravenous thrombolysis.’, European journal of neurology, 24(2), pp. 262–269. Available at: https://doi.org/10.1111/ene.13179.
Gensicke H et al. (2016) ‘Impact of body mass index on outcome in stroke patients treated with intravenous thrombolysis.’, European journal of neurology, 23(12), pp. 1705–1712. Available at: https://doi.org/10.1111/ene.13071.
Gensicke H et al. (2016) ‘Impact of body mass index on outcome in stroke patients treated with intravenous thrombolysis.’, European journal of neurology, 23(12), pp. 1705–1712. Available at: https://doi.org/10.1111/ene.13071.
Gensicke H et al. (2016) ‘Intravenous Thrombolysis in Patients Dependent on the Daily Help of Others Before Stroke.’, Stroke, 47(2), pp. 450–6. Available at: https://doi.org/10.1161/strokeaha.115.011674.
Gensicke H et al. (2016) ‘Intravenous Thrombolysis in Patients Dependent on the Daily Help of Others Before Stroke.’, Stroke, 47(2), pp. 450–6. Available at: https://doi.org/10.1161/strokeaha.115.011674.
Gensicke, Henrik et al. (2013) ‘IV thrombolysis and renal function’, Neurology : journal of the American Academy of Neurology, 81(20), pp. 1780–8. Available at: https://doi.org/10.1212/01.wnl.0000435550.83200.9e.
Gensicke, Henrik et al. (2013) ‘IV thrombolysis and renal function’, Neurology : journal of the American Academy of Neurology, 81(20), pp. 1780–8. Available at: https://doi.org/10.1212/01.wnl.0000435550.83200.9e.
Members (2)
Stefan Engelter
Co-PI, Founder