PD Dr. med. Julie Refardt

Sailer, Clara O., Vogel, Cyril F., Monnerat, Sophie, Probst, Leila, Christ-Crain, Mirjam, Winzeler, Bettina, & Refardt, Julie. (2026). Changes in fibroblast growth factor 21 levels associated with alcohol consumption and smoking cessation. Endocrine Connections, 15. https://doi.org/10.1530/EC-25-0713

Savelberg, Angelique B.M.C., Hoorn, Ewout J., & Refardt, Julie C. (2026). Management of Chronic Hyponatremia in the Outpatient Setting. American Journal of Kidney Diseases, 87, 87–92. https://doi.org/10.1053/j.ajkd.2025.06.024

Potasso, Laura, Christ-Crain, Mirjam, & Refardt, Julie. (2025). Impact of hyponatremia on bone, a narrative review. European Journal of Endocrinology, 193, R89–R97. https://doi.org/10.1093/ejendo/lvaf241

Potasso, Laura, Refardt, Julie, Monnerat, Sophie, Meier, Christian, & Christ-Crain, Mirjam. (2025). Normalization of hyponatremia in hospitalized patients decreases osteoclast activity. European Journal of Endocrinology, 193, 651–658. https://doi.org/10.1093/ejendo/lvaf242

van der Groef, R., van Zanten, S. V., van Beekveld, D., Mulugeta, E., Refardt, J., & Neggers, S. J. C. M. M. (2025). Long-term antitumour effects of pasireotide in acromegaly. 193. https://doi.org/10.1093/ejendo/lvaf194

Monnerat, S., Christ-Crain, M., & Refardt, J. (2025). Hyponatraemia in ageing. Nature Reviews Endocrinology, 21. https://doi.org/10.1038/s41574-025-01138-4

Hepprich, Matthias, Romberg, Christina, Mudry, Jonathan, Refardt, Julie, Wild, Damian, Antwi, Kwadwo, & Christ, Emanuel. (2025). Exenatide for diagnosing endogenous hyperinsulinemic hypoglycemia: a randomized placebo-controlled, double-blind, cross-over proof-of-principle study. European Journal of Endocrinology, 193(2), 247–254. https://doi.org/10.1093/ejendo/lvaf153

Nikaj, Andi, Atila, Cihan, Chifu, Irina, Ferrante, Emanuele, Erlic, Zoran, Drummond, Juliana B, Indirli, Rita, Drexhage, Roosmarijn, Powlson, Andrew S, Gurnell, Mark, Soares, Beatriz S, Hofland, Johannes, Beuschlein, Felix, Fassnacht, Martin, Winzeler, Bettina, Refardt, Julie, & Christ-Crain, Mirjam. (2025). Disrupted ACTH and cortisol response to osmotic and non-osmotic stress in patients with arginine vasopressin deficiency. European Journal of Endocrinology, 193, 1–9. https://doi.org/10.1093/ejendo/lvaf119

Atila, Cihan, Chifu, Irina, Drummond, Juliana B, Vogt, Deborah R, Nahum, Uri, Fassnacht, Martin, Winzeler, Bettina, Refardt, Julie, & Christ-Crain, Mirjam. (2025). A novel diagnostic score for diagnosing arginine vasopressin deficiency (central diabetes insipidus) or primary polydipsia with basal laboratory and clinical parameters: results from two international multicentre prospective diagnostic studies. Lancet Diabetes and Endocrinology, 13, 505–515. https://doi.org/10.1016/s2213-8587(25)00053-1

Atila, Cihan, Winzeler, Bettina, Chifu, Irina, Fassnacht, Martin, Refardt, Julie, & Christ-Crain, Mirjam. (2025). A post-hoc internal validation of arginine-stimulated copeptin cut-offs for diagnosing AVP deficiency (central diabetes insipidus). Pituitary, 28(3). https://doi.org/10.1007/s11102-025-01523-2

Siebenhüner, A. R., Refardt, J., Nicolas, G. P., Kaderli, R., Walter, M. A., Perren, A., & Christ, E. (2025). Impact of multikinase inhibitors in reshaping the treatment of advanced gastroenteropancreatic neuroendocrine tumors [Journal-article]. Endocrine-Related Cancer, 32(6). https://doi.org/10.1530/erc-25-0052

Atila, Cihan, Lustenberger, Sven, Chifu, Irina, Ferrante, Emanuele, Erlic, Zoran, Drummond, Juliana B., Indirli, Rita, Drexhage, Roosmarijn, Powlson, Andrew S., Gurnell, Mark, Santana Soares, Beatriz, Hofland, Johannes, Beuschlein, Felix, Fassnacht, Martin, Winzeler, Bettina, Refardt, Julie, & Christ-Crain, Mirjam. (2025). Relationship between plasma urea and copeptin in response to arginine stimulation in healthy adults, patients with vasopressin deficiency and primary polydipsia. Pituitary, 28(1). https://doi.org/10.1007/s11102-024-01489-7

Pelouto, A., Monnerat, S., Refardt, J., Zandbergen, A. A. M., Christ-Crain, M., & Hoorn, E. J. (2025). Clinical factors associated with hyponatremia correction during treatment with oral urea [Journal-article]. Nephrology Dialysis Transplantation, 40(2), 283–293. https://doi.org/10.1093/ndt/gfae164

Refardt, Julie. (2025). Special considerations of hyponatremia in the elderly patient. Best Practice and Research Clinical Endocrinology and Metabolism. https://doi.org/10.1016/j.beem.2025.102040

Bizzozero, Chiara Angela, Monnerat, Sophie, Chapman, Fiona A., Dhaun, Neeraj, Refardt, Julie, & Christ-Crain, Mirjam. (2024). Apelin levels in patients with polyuria-polydipsia syndrome upon copeptin stimulation tests. European Journal of Endocrinology, 191(5), 491–498. https://doi.org/10.1093/ejendo/lvae138

Atila, Cihan, Refardt, Julie, & Christ-Crain, Mirjam. (2024). Correction to: Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency (Nature Reviews Endocrinology, (2024), 20, 8, (487-500), 10.1038/s41574-024-00985-x). Nature Reviews Endocrinology, 20(8). https://doi.org/10.1038/s41574-024-00998-6

Atila, Cihan, Refardt, Julie, & Christ-Crain, Mirjam. (2024). Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency. Nature Reviews Endocrinology, 20(8), 487–500. https://doi.org/10.1038/s41574-024-00985-x

Monnerat, Sophie, Drivakos, Nikolaos, Chapman, Fiona A., Dhaun, Neeraj, Refardt, Julie, & Christ-Crain, Mirjam. (2024). Apelin and Copeptin Levels in Patients With Chronic SIAD Treated With Empagliflozin. Journal of the Endocrine Society, 8(7). https://doi.org/10.1210/jendso/bvae106

Refardt, Julie, Atila, Cihan, & Christ-Crain, Mirjam. (2024). New insights on diagnosis and treatment of AVP deficiency. Reviews in Endocrine and Metabolic Disorders, 25(3), 639–649. https://doi.org/10.1007/s11154-023-09862-w

Atila, Cihan, Beck, Julia, Refardt, Julie, Erlic, Zoran, Drummond, Juliana B., Sailer, Clara O., Liechti, Matthias E., Rocha, Beatriz Santana Soares, Beuschlein, Felix, Winzeler, Bettina, & Christ-Crain, Mirjam. (2024). Psychopathological characteristics in patients with arginine vasopressin deficiency (central diabetes insipidus) and primary polydipsia compared to healthy controls. European Journal of Endocrinology, 190(5), 354–362. https://doi.org/10.1093/ejendo/lvae040

Hofland, Johannes, Refardt, Julie C., Feelders, Richard A., Christ, Emanuel, & de Herder, Wouter W. (2024). Approach to the Patient: Insulinoma [Journal-article]. Journal of Clinical Endocrinology and Metabolism, 109(4), 1109–1118. https://doi.org/10.1210/clinem/dgad641

Beck, Julia, Siebenhüner, Alexander, Wild, Damian, Christ, Emanuel, & Refardt, Julie. (2024). Impact of sex on treatment decisions and outcome in patients with neuroendocrine neoplasms. Endocrine-Related Cancer, 31(3). https://doi.org/10.1530/erc-23-0235

Refardt, Julie, Vogt, Deborah R., & Christ-Crain, Mirjam. (2024). Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency. New England Journal of Medicine, 390(3), 288–290. https://doi.org/10.1056/nejmc2314326

Radvanyi, Z., Yoo, E. J., Kandasamy, P., Salas-Bastos, A., Monnerat, S., Refardt, J., Christ-Crain, M., Hayashi, H., Kondo, Y., Jantsch, J., Rubio-Aliaga, I., Sommer, L., Wagner, C. A., Hediger, M. A., Kwon, H. M., Loffing, J., & Pathare, G. (2024). Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation [Journal-article]. Journal of Biological Chemistry, 300(1), 105480. https://doi.org/10.1016/j.jbc.2023.105480

Sterns RH, Rondon-Berrios H, Adrogué HJ, Berl T, Burst V, Cohen DM, Christ-Crain M, Cuesta M, Decaux G, Emmett M, Garrahy A, Gankam-Kengne F, Hix JK, Hoorn EJ, Kamel KS, Madias NE, Peri A, Refardt J, Rosner MH, et al. (2024). Treatment Guidelines for Hyponatremia Stay the Course. Clinical Journal of the American Society of Nephrology, 19(1), 129–135. https://doi.org/10.2215/cjn.0000000000000244

Sailer CO, Kuehne JM, da Conceição I, Refardt J, Christ-Crain M, & Winzeler B. (2023). Hypothalamic–pituitary–adrenal axis activity in patients with primary polydipsia compared to healthy controls. Clinical Endocrinology, 99(6), 535–544. https://doi.org/10.1111/cen.14835

Refardt, Julie, Atila, Cihan, Chifu, Irina, Ferrante, Emanuele, Erlic, Zoran, Drummond, Juliana B., Indirli, Rita, Drexhage, Roosmarijn C., Sailer, Clara O., Widmer, Andrea, Felder, Susan, Powlson, Andrew S., Hutter, Nina, Gurnell, Mark, Soares, Beatriz S., Hofland, Johannes, Beuschlein, Felix, Fassnacht, Martin, Winzeler, Bettina, & Christ-Crain, Mirjam. (2023). Arginine or Hypertonic Saline.Stimulated Copeptin to Diagnose AVP Deficiency [Journal-article]. New England Journal of Medicine, 389(20), 1877–1887. https://doi.org/10.1056/nejmoa2306263

Monnerat S, Christ-Crain M, & Refardt J. (2023). One Liter a Day, Keeps the Doctor Away (Patent No. 11). Journal of Clinical Endocrinology and Metabolism, 108(11), Article 11. https://doi.org/10.1210/clinem/dgad217

Monnerat S, Refardt J, Potasso L, Meier C, & Christ-Crain M. (2023). An Increase in Plasma Sodium Levels Is Associated With an Increase in Osteoblast Function in Chronic SIAD. Journal of Clinical Endocrinology and Metabolism, 108(10), e1027–e1033. https://doi.org/10.1210/clinem/dgad238

Potasso, Laura, Monnerat, Sophie, Refardt, Julie, Lindner, Gregor, Burst, Volker, Winzeler, Bettina, & Christ-Crain, Mirjam. (2023). Chloride and Potassium Assessment Is a Helpful Tool for Differential Diagnosis of Thiazide-Associated Hyponatremia. Journal of Clinical Endocrinology and Metabolism, 108(9), 2248–2254. https://doi.org/10.1210/clinem/dgad133

Monnerat, Sophie, Atila, Cihan, Baur, Fabienne, de Jesus, Joyce Santos, Refardt, Julie, Dickenmann, Michael, & Christ-Crain, Mirjam. (2023). Effect of protein supplementation on plasma sodium levels in the syndrome of inappropriate antidiuresis: a monocentric, open-label, proof-of-concept study—the TREASURE study. European Journal of Endocrinology, 189(2), 252–261. https://doi.org/10.1093/ejendo/lvad108

Radvanyi, Z., Yoo, E. J., Kandasamy, P., Salas-Bastos, A., Monnerat, S., Refardt, J., Christ-Crain, M., Hayashi, H., Kondo, Y., Jantsch, J., Rubio-Aliaga, I., Sommer, L., Wagner, C. A., Hediger, M. A., Kwon, H. M., Loffing, J., & Pathare, G. (2023). Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2023.06.23.546282

Monnerat S, Atila C, Refardt J, & Christ-Crain M. (2023). Prevalence of Admission Hyponatremia in Patients With Diabetes Treated With and Without an SGLT2 inhibitor. Journal of the Endocrine Society, 7(4), bvad011. https://doi.org/10.1210/jendso/bvad011

Schmidlin, Moira, Sadowski, Samira M., Siebenhüner, Alexander, Wild, Damian, Christ, Emanuel, & Refardt, Julie. (2023). Improvement of Lung NET Management through Standardized Care—A Swiss Nationwide Observational Study. Cancers, 15(8). https://doi.org/10.3390/cancers15082270

Pelouto A, Refardt JC, Christ-Crain M, Zandbergen AAM, & Hoorn EJ. (2023). Overcorrection and undercorrection with fixed dosing of bolus hypertonic saline for symptomatic hyponatremia. European Journal of Endocrinology, 188(3), 322–330. https://doi.org/10.1093/ejendo/lvad028

Refardt J, Imber C, Nobbenhuis R, Sailer CO, Haslbauer A, Monnerat S, Bathelt C, Vogt DR, Berres M, Winzeler B, Bridenbaugh SA, & Christ-Crain M. (2023). Treatment Effect of the SGLT2 Inhibitor Empagliflozin on Chronic Syndrome of Inappropriate Antidiuresis: Results of a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial. Journal of the American Society of Nephrology, 34(2), 322–332. https://doi.org/10.1681/asn.2022050623

Klomp MJ, Refardt J, van Koetsveld PM, Campana C, Dalm SU, Dogan F, van Velthuysen MF, Feelders RA, de Herder WW, Hofland J, & Hofland LJ. (2023). Epigenetic regulation of SST2 expression in small intestinal neuroendocrine tumors. Frontiers in Endocrinology, 14, 1184436. https://doi.org/10.3389/fendo.2023.1184436

Rhonheimer, Lena, Refardt, Julie, & Christ, Emanuel. (2023). Epidemiology and management of neuroendocrine neoplasms of unknown origin: an overview. Austrian Journal of Clinical Endocrinology and Metabolism, 16, 138–145. https://doi.org/10.1007/s41969-023-00217-z

Nahum U, Refardt J, Chifu I, Fenske WK, Fassnacht M, Szinnai G, Christ-Crain M, & Pfister M. (2022). Machine learning-based algorithm as an innovative approach for the differentiation between diabetes insipidus and primary polydipsia in clinical practice. European Journal of Endocrinology, 187(6), 777–786. https://doi.org/10.1530/eje-22-0368

Atila C, Loughrey PB, Garrahy A, Winzeler B, Refardt J, Gildroy P, Hamza M., Pal A, Verbalis JG, Thompson CJ, Hemkens L.G., Hunter SJ, Sherlock M, Levy MJ, Karavitaki N., Newell-Price J, Wass JAH, & Christ-Crain M. (2022). Central diabetes insipidus from a patient’s perspective: management, psychological co-morbidities, and renaming of the condition: results from an international web-based survey. The Lancet Diabetes and Endocrinology, 10(10), 700–709. https://doi.org/10.1016/s2213-8587(22)00219-4

Atila C, Monnerat S, Urwyler SA, Refardt J, Winzeler B, & Christ-Crain M. (2022). The effect of glucose dynamics on plasma copeptin levels upon glucagon, arginine, and macimorelin stimulation in healthy adults: Data from: Glucacop, Macicop, and CARGO study. Pituitary, 25(4), 636–644. https://doi.org/10.1007/s11102-022-01240-0

Refardt J, Brabander T, Minczeles NS, Feelders RA, de Herder WW, & Hofland J. (2022). Prognostic value of dysnatremia for survival in neuroendocrine neoplasm patients. European Journal of Endocrinology, 187(1), 209–217. https://doi.org/10.1530/eje-22-0023

Refardt J, Hofland J, Wild D., & Christ E. (2022). Molecular Imaging of Neuroendocrine Neoplasms. Journal of Clinical Endocrinology and Metabolism, 107(7), E2662–E2670. https://doi.org/10.1210/clinem/dgac207

Refardt J, Klomp MJ, van Koetsveld PM, Dogan F, Konijnenberg M, Brabander T, Feelders RA, de Herder WW, Hofland LJ, & Hofland J. (2022). Effect of epigenetic treatment on SST(2) expression in neuroendocrine tumour patients. (Patent No. 7). 12(7), Article 7. https://doi.org/10.1002/ctm2.957

Christ-Crain M, Refardt J, & Winzeler B. (2022). Approach to the Patient: “Utility of the Copeptin Assay”. Journal of Clinical Endocrinology and Metabolism, 107(6), 1727–1738. https://doi.org/10.1210/clinem/dgac070

Christ E, Wild D, & Refardt J. (2022). Molecular Imaging in neuroendocrine neoplasias. Presse Medicale, 51(2), 104115. https://doi.org/10.1016/j.lpm.2022.104115

Atila, C., Monnerat, S., Urwyler, S. A., Refardt, J., Winzeler, B., & Christ-Crain, M. (2022, May 12). The effect of glucose dynamics on plasma copeptin levels upon glucagon, arginine, and macimorelin stimulation in healthy adults [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-1636018/v1

Refardt J, den Hoed CM, Langendonk J, Zandee WT, Charehbili A, Feelders RA, de Herder WW, Brabander T, & Hofland J. (2022). Prognostic significance of hyperammonemia in neuroendocrine neoplasm patients with liver metastases. Endocrine-Related Cancer, 29(5), 241–250. https://doi.org/10.1530/erc-21-0346

Sailer, C. O., Kühne, J. M., Conceição, I. d., Refardt, J., Christ-Crain, M., & Winzeler, B. (2022, March 3). Hypothalamic-pituitary-adrenal axis activity in patients with primary polydipsia compared to healthy volunteers [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-1370576/v1

Potasso, Laura, Refardt, Julie, De Marchis, Gian Marco, Wiencierz, Andrea, Wright, Patrick R, Wagner, Benjamin, Dittrich, Tolga, Polymeris, Alexandros A, Gensicke, Henrik, Bonati, Leo H, & Christ-Crain, Mirjam. (2022). Impact of Sodium Levels on Functional Outcomes in Patients with Stroke - A Swiss Stroke Registry Analysis. Journal of Clinical Endocrinology and Metabolism, 107(2), E672–E680. https://doi.org/10.1210/clinem/dgab650

Potasso L, Refardt J, De Marchis GM, Wiencierz A, Wright PR, Wagner B, Dittrich T, Polymeris AA, Gensicke H, Bonati LH, & Christ-Crain M. (2022). Impact of Sodium Levels on Functional Outcomes in Patients with Stroke - A Swiss Stroke Registry Analysis. Journal of Clinical Endocrinology and Metabolism, 107(2), E672–E680. https://doi.org/10.1210/clinem/dgab650

Potasso L, Potasso L, Refardt J., Meier C, & Christ-Crain M. (2022). Effect of hyponatremia normalization on osteoblast function in patients with SIAD. European Journal of Endocrinology, 186(1), 1–8. https://doi.org/10.1530/eje-21-0604

Refardt J, Hofland J, Wild D, & Christ E. (2021). New Directions in Imaging Neuroendocrine Neoplasms. Current Oncology Reports, 23(12), 143. https://doi.org/10.1007/s11912-021-01139-2

Sailer C.O., Refardt J, Blum CA, Schnyder I, Molina-Tijeras J.A., Fenske W., Christ-Crain M., & Christ-Crain M. (2021). Validity of different copeptin assays in the differential diagnosis of the polyuria-polydipsia syndrome. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-89505-9

Refardt J, Pelouto A, Potasso L, Hoorn EJ, & Christ-Crain M. (2021). Hyponatremia Intervention Trial (HIT): Study Protocol of a Randomized, Controlled, Parallel-Group Trial With Blinded Outcome Assessment. Frontiers in Medicine, 8, 729545. https://doi.org/10.3389/fmed.2021.729545

Refardt J, Hofland J, Kwadwo A, Nicolas GP, Rottenburger C, Fani M, Wild D, & Christ E. (2021). Theranostics in neuroendocrine tumors: an overview of current approaches and future challenges. Reviews in Endocrine and Metabolic Disorders, 22(3), 581–594. https://doi.org/10.1007/s11154-020-09552-x

Sailer C.O., Winzeler B, Urwyler SA, Schnyder I., Refardt J, Eckert A., Varghese N., Fassnacht M., Chifu I., Lawson E.A., Verbalis J.G., Fenske W., & Christ-Crain M. (2021). Oxytocin levels in response to pituitary provocation tests in healthy volunteers. European Journal of Endocrinology, 185(3), 355–364. https://doi.org/10.1530/eje-21-0346

Christ-Crain M, Winzeler B, & Refardt J. (2021). Diagnosis and management of diabetes insipidus for the internist: an update. Journal of Internal Medicine, 290(1), 73–87. https://doi.org/10.1111/joim.13261

Nobbenhuis R, Nobbenhuis R, Refardt J, Vogt D, Sailer CO, Winzeler B, & Christ-Crain M. (2021). Can treatment response to SGLT2-inhibitors in syndrome of inappropriate antidiuresis be predicted by copeptin, natriuretic peptides and inflammatory markers? Biomarkers, 26(7), 647–655. https://doi.org/10.1080/1354750x.2021.1970808

Potasso L, Potasso L, Refardt J., Chifu I., Fassnacht M, Fenske W.K., & Christ-Crain M. (2021). Incidence of hyperkalemia during hypertonic saline test for the diagnosis of diabetes insipidus. Endocrine Connections, 10(4), 401–409. https://doi.org/10.1530/ec-20-0531

Winzeler, Bettina, Sailer, Clara O, Coynel, David, Zanchi, Davide, Vogt, Deborah R, Urwyler, Sandrine A, Refardt, Julie, & Christ-Crain, Mirjam. (2021). A randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia. Journal of Clinical Investigation, 131(20), e151800. https://doi.org/10.1172/jci151800

Winzeler B, Sailer C.O., Coynel D., Zanchi D., Vogt DR, Urwyler SA, Refardt J, & Christ-Crain M. (2021). A randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia. Journal of Clinical Investigation, 131(20). https://doi.org/10.1172/jci151800

Refardt J, Zandee WT, Brabander T, Feelders RA, Franssen GJH, Hofland LJ, Christ E, de Herder WW, & Hofland J. (2020). Inferior outcome of neuroendocrine tumor patients negative on somatostatin receptor imaging. Endocrine-Related Cancer, 27(11), 615–624. https://doi.org/10.1530/erc-20-0340

Winzeler B, da Conceição I, Refardt J, Sailer CO, Dutilh G, & Christ-Crain M. (2020). Effects of glucagon-like peptide-1 receptor agonists on fluid intake in healthy volunteers. Endocrine, 70(2), 292–298. https://doi.org/10.1007/s12020-020-02394-2

Winzeler B, Morin B, Refardt J, Imber C, Fenske W, Sailer CO, Holbro A, & Christ-Crain M. (2020). Low arginine vasopressin levels in patients with diabetes insipidus are not associated with anaemia. Clinical Endocrinology, 93(4), 456–465. https://doi.org/10.1111/cen.14265

Refardt J. (2020). Diagnosis and differential diagnosis of diabetes insipidus: Update. Best Practice and Research: Clinical Endocrinology and Metabolism, 34(5), 101398. https://doi.org/10.1016/j.beem.2020.101398

Refardt J, Winzeler B, & Christ-Crain M. (2020). Diabetes Insipidus: An Update. Endocrinology and Metabolism Clinics of North America, 49(3), 517–531. https://doi.org/10.1016/j.ecl.2020.05.012

Bologna K, Cesana-Nigro N, Refardt J, Imber C, Vogt DR, Christ-Crain M, & Winzeler B. (2020). Effect of arginine on the hypothalamic–pituitary–adrenal axis in individuals with and without vasopressin deficiency. Journal of Clinical Endocrinology and Metabolism, 105(7). https://doi.org/10.1210/clinem/dgaa157

Refardt J, & Christ-Crain M. (2020). Copeptin-based diagnosis of diabetes insipidus. Swiss Medical Weekly, 150(1920), w20237. https://doi.org/10.4414/smw.2020.20237

Sailer CO, Refardt J, Bissig S, Bologna K, Imber C, & Christ-Crain M. (2020). Effects of alcohol consumption on copeptin levels and sodium-water homeostasis. American Journal of Physiology - Renal Physiology, 318(3), F702–F709. https://doi.org/10.1152/ajprenal.00458.2019

Refardt J, Imber C, Sailer CO, Jeanloz N, Potasso L, Kutz A, Widmer A, Urwyler SA, Ebrahimi F, Vogt DR, Winzeler B, & Christ-Crain M. (2020). A randomized trial of empagliflozin to increase plasma sodium levels in patients with the syndrome of inappropriate antidiuresis. Journal of the American Society of Nephrology, 31(3), 615–624. https://doi.org/10.1681/asn.2019090944

Winzeler B, Steinmetz M, Refardt J, Cesana-Nigro N, Popovic M, Fenske W, & Christ-Crain M. (2020). Copeptin is not useful as a marker of malignant disease in the syndrome of inappropriate antidiuresis. Endocrine Connections, 9(1), 20–27. https://doi.org/10.1530/ec-19-0431

Winzeler B, Cesana-Nigro N, Refardt J, Vogt DR, Imber C, Morin B, Popovic M, Steinmetz M, Sailer CO, Szinnai G, Chifu I, Fassnacht M, & Christ-Crain M. (2019). Arginine-stimulated copeptin measurements in the differential diagnosis of diabetes insipidus: a prospective diagnostic study. The Lancet, 394(10198), 587–595. https://doi.org/10.1016/s0140-6736(19)31255-3

Blum, Claudine A., Schuetz, Philipp, Nigro, Nicole, Winzeler, Bettina, Arici, Birsen, Refardt, Julie, Urwyler, Sandrine A., Rodondi, Nicolas, Blum, Manuel R., Briel, Matthias, Müller, Beat, & Christ-Crain, Mirjam. (2019). Cosyntropin testing does not predict response to glucocorticoids in community-acquired pneumonia in a randomized controlled trial. Clinical Endocrinology, 91(3), 374–382. https://doi.org/10.1111/cen.13907

Brown, Peter, Zhou, Yaoqi, Tan, Aik-Choon, El-Esawi, Mohamed A., Liehr, Thomas, Blanck, Oliver, Gladue, Douglas P., Almeida, Gabriel M.F., Cernava, Tomislav, Sorzano, Carlos O., Yeung, Andy W.K., Engel, Michael S., Chandrasekaran, Arun R., Muth, Thilo, Staege, Martin S., Daulatabad, Swapna V., Widera, Darius, Zhang, Junpeng, Meule, Adrian, et al. (2019). Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database, 2019, 1–67. https://doi.org/10.1093/database/baz085

Refardt, Julie, Sailer, Clara O. Odilia, Chifu, Irina, Winzeler, Bettina, Schnyder, Ingeborg, Fassnacht, Martin, Fenske, Wiebke Kristin, & Christ-Crain, Mirjam. (2019). The challenges of sodium measurements - indirect versus direct ion selective method. European Journal of Endocrinology, 181(2), 193–199. https://doi.org/10.1530/eje-19-0101

Refardt, Julie, Winzeler, Bettina, & Christ-Crain, Mirjam. (2019). Copeptin and its role in the diagnosis of diabetes insipidus and the syndrome of inappropriate antidiuresis. Clinical Endocrinology, 91(1), 22–32. https://doi.org/10.1111/cen.13991

Winzeler B, da Conceição I, Refardt J, Sailer CO, Dutilh G, & Christ-Crain M. (2019). Effects of glucagon-like peptide-1 receptor agonists on hypothalamic-pituitary-adrenal axis in healthy volunteers. Journal of Clinical Endocrinology and Metabolism, 104(1), 202–208. https://doi.org/10.1210/jc.2018-01420

Refardt J, & Christ-Crain M. (2018). Diabetes insipidus in pregnancy: How to advice the patient? Minerva Endocrinologica, 43(4), 458–464. https://doi.org/10.23736/s0391-1977.18.02807-9

Refardt J, Kling B, Krausert K, Fassnacht M, von Felten S, Christ-Crain M, & Fenske W. (2018). Impact of chronic hyponatremia on neurocognitive and neuromuscular function. European Journal of Clinical Investigation, 48(11), e13022. https://doi.org/10.1111/eci.13022

Refardt, Julie, Farina, Patricia, Hoesli, Irene, & Meier, Christian. (2018). Hypercalcemic crisis in third trimenon: evaluating the optimal treatment strategy. Gynecological Endocrinology, 34(10), 833–836. https://doi.org/10.1080/09513590.2018.1462314

Fenske W, Refardt J, Chifu I, Schnyder I, Winzeler B, Drummond J, Ribeiro-Oliveira A Jr, Drescher T, Bilz S, Vogt DR, Malzahn U, Kroiss M, Christ E, Henzen C, Fischli S, Tönjes A, Mueller B, Schopohl J, Flitsch J, et al. (2018). A copeptin-based approach in the diagnosis of diabetes insipidus. New England Journal of Medicine, 379(5), 428–439. https://doi.org/10.1056/nejmoa1803760

Nigro N, Winzeler B, Suter-Widmer I, Schuetz P, Arici B, Bally M, Refardt J, Betz M, Gashi G, Urwyler SA, Burget L, Blum CA, Bock A, Huber A, Müller B, & Christ-Crain M. (2018). Copeptin levels and commonly used laboratory parameters in hospitalised patients with severe hypernatraemia - the ‘Co-MED study’. Critical Care, 22(1), 33. https://doi.org/10.1186/s13054-018-1955-7

Fenske, Wiebke, Refardt, Julie, & Christ-Crain, Mirjam. (2018). Copeptin in the Diagnosis of Diabetes Insipidus. The New England Journal of Medicine, 379(18), 1785–1786. https://doi.org/10.1056/nejmc1811694

Hochuli, Michel, Bollhalder, Sandra, Thierer, Carina, Refardt, Julie, Gerber, Philipp, & Baumgartner, Matthias R. (2018). Effects of Inadequate Amino Acid Mixture Intake on Nutrient Supply of Adult Patients with Phenylketonuria. Annals of Nutrition and Metabolism, 71(3-4), 129–135. https://doi.org/10.1159/000479746

Refardt, Julie, Sailer, Clara Odilia, Winzeler, Bettina, Betz, Matthias Johannes, Chifu, Irina, Schnyder, Ingeborg, Fassnacht, Martin, Fenske, Wiebke, & Christ-Crain, Mirjam. (2018). FGF-21 levels in polyuria-polydipsia syndrome. Endocrine Connections, 7(12), 1501–1506. https://doi.org/10.1530/ec-18-0469

Refardt J, Winzeler B, Meienberg F, & Christ-Crain M. (2017). Artificial Syndrome of Inappropriate Antidiuresis Model as Potential Use for Diagnostic and Therapeutic Strategies. Hormone and Metabolic Research, 49(9), 673–679. https://doi.org/10.1055/s-0043-113450

Refardt J, Winzeler B, Meienberg F, Vogt DR, & Christ-Crain M. (2017). Empagliflozin Increases Short-Term Urinary Volume Output in Artificially Induced Syndrome of Inappropriate Antidiuresis. International Journal of Endocrinology, 2017, 7815690. https://doi.org/10.1155/2017/7815690

Blum, C., Nigro, N., Briel, M., Schuetz, P., Ullmer, E., Suter-Widmer, I., Winzeler, B., Bingisser, R., Elsaesser, H., Drozdov, D., Arici, B., Urwyler, S., Refardt, J., Tarr, P., Wirz, S., Thomann, R., Baumgartner, C., Duplain, H., Burki, D., et al. (2015). Adjunct prednisone therapy for patients with community-acquired pneumonia: a randomized, placebo-controlled multicenter trial [Journal-article]. Critical Care, 19(Suppl 1), P125. https://doi.org/10.1186/cc14205