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Taji Heravi, Ala, Gryaznov, Dmitry, Busse, Jason W., Schönenberger, Christof Manuel, von Niederhäusern, Belinda, Hausheer, Lena, Covino, Manuela, Schwenke, Johannes M., Epp, Selina, Griessbach, Alexandra, Chiaborelli, Malena, Agarwal, Arnav, Lohner, Szimonetta, Hirt, Julian, Schandelmaier, Stefan, Egli, Simon B., Makhele, Moshao Amos, Amstutz, Alain, Mertz, Dominik, et al. (2025). Metaresearch on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias. Journal of Clinical Epidemiology, 185. https://doi.org/10.1016/j.jclinepi.2025.111822
Audige, Annette, Amstutz, Alain, Schuurmans, Mace M., Amico, Patrizia, Braun, Dominique L., Stoeckle, Marcel P., Hasse, Barbara, Hage, Rene, Damm, Dominik, Tamm, Michael, Mueller, Nicolas J., Gunthard, Huldrych F., Koller, Michael T., Schonenberger, Christof M., Griessbach, Alexandra, Labhardt, Niklaus D., Kouyos, Roger D., Trkola, Alexandra, Huber, Michael, et al. (2025). Low agreement and frequent invalid controls in two SARS-CoV-2 T-cell assays in people with compromised immune function. PLoS ONE, 20(1 January). https://doi.org/10.1371/journal.pone.0317965
Griessbach, Alexandra, Speich, Benjamin, Amstutz, Alain, Hausheer, Lena, Covino, Manuela, Wnfried Ramirez, Hillary, Schandelmaier, Stefan, Taji Heravi, Ala, Treweek, Shaun, Schwenkglenks, Matthias, Briel, Matthias, , Hemkens, Lars G., Kasenda, Benjamin, Pauli-Magnus, Christiane, & McLennan, Stuart. (2024). Resource use and costs of investigator-sponsored randomized clinical trials in Switzerland, Germany, and the United Kingdom: a metaresearch study. Journal of Clinical Epidemiology, 176. https://doi.org/10.1016/j.jclinepi.2024.111536
Griessbach, Alexandra, , Dutilh, Gilles, Treweek, Shaun, Schwenkglenks, Matthias, & Briel, Matthias. (2024). Design and rationale for an empirical investigation of the resource use and costs of investigator-initiated randomized trials in Switzerland, the UK, and Germany [Journal-article]. Trials, 25(1). https://doi.org/10.1186/s13063-024-08505-y
Amstutz, Alain, Chammartin, Frédérique, Audigé, Annette, Eichenberger, Anna L., Braun, Dominique L., Amico, Patrizia, Stoeckle, Marcel P., Hasse, B., Papadimitriou-Olivgeris, Matthaios, Manuel, Oriol, Bongard, Cédric, Schuurmans, Macé, Hage, René, Damm, Dominik, Tamm, Michael, Mueller, Nicolas J., Rauch, A., Günthard, H.F., Koller, Michael T., et al. (2024). Antibody and T-Cell Response to Bivalent Booster SARS-CoV-2 Vaccines in People With Compromised Immune Function: COVERALL-3 Study. Journal of Infectious Diseases, 230(4), e847–e859. https://doi.org/10.1093/infdis/jiae291
Amstutz, Alain, Schönenberger, Christof M., , Griessbach, Alexandra, Schwenke, Johannes M., Glasstetter, Jan, James, Sophie, Verkooijen, Helena M., Nickolls, Beverley, Relton, Clare, Hemkens, Lars G., Chammartin, Frédérique, Gerber, Felix, Labhardt, Niklaus D., Schandelmaier, Stefan, & Briel, Matthias. (2024). Characteristics, consent patterns, and challenges of randomized trials using the Trials within Cohorts (TwiCs) design - A scoping review. Journal of Clinical Epidemiology, 174. https://doi.org/10.1016/j.jclinepi.2024.111469
Østengaard, Lasse, Barrientos, Ariel, Boutron, Isabelle, Chan, An‐Wen, Collins, Gary, Hopewell, Sally, Moher, David, Nejstgaard, Camilla Hansen, Schulz, Kenneth F., , Tang, Evan, Tunn, Ruth, Watanabe, Nozomi, Xu, Chenchen, & Hróbjartsson, Asbjørn. (2024). Development of a topic‐specific bibliographic database supporting the updates of SPIRIT 2013 and CONSORT 2010. Cochrane Evidence Synthesis and Methods, 2(5). https://doi.org/10.1002/cesm.12057
Griessbach, Alexandra, Schönenberger, Christof Manuel, Taji Heravi, Ala, Gloy, Viktoria, Agarwal, Arnav, Hallenberger, Tim Jonas, Schandelmaier, Stefan, Janiaud, Perrine, Amstutz, Alain, Covino, Manuela, Mall, David, , & Briel, Matthias. (2024). Characteristics, Progression, and Output of Randomized Platform Trials: A Systematic Review [Journal-article]. JAMA Network Open, 7(3), e243109. https://doi.org/10.1001/jamanetworkopen.2024.3109
Chammartin, Frédérique, Griessbach, Alexandra, Kusejko, Katharina, Audigé, Annette, Epp, Selina, Stoeckle, Marcel P., Eichenberger, Anna L., Amstutz, Alain, Schoenenberger, Christof M., Hasse, Barbara, Braun, Dominique L., Rauch, Andri, Trkola, Alexandra, Briel, Matthias, Bucher, Heiner C., Günthard, Huldrych F., , & Abela, Irene A. (2024). Bridging the gap: identifying factors impacting mRNA severe acute respiratory syndrome coronavirus 2 vaccine booster response in people with HIV-1. Aids, 38(2), 217–222. https://doi.org/10.1097/qad.0000000000003751
Lüthi, Hualin, Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Laager, Mirjam, Vogt, Deborah R., Hemkens, Lars G., , Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., et al. (2024). Effect of dulaglutide in promoting abstinence during smoking cessation: 12-month follow-up of a single-centre, randomised, double-blind, placebo-controlled, parallel group trial. eClinicalMedicine, 68. https://doi.org/10.1016/j.eclinm.2024.102429
Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Coynel, David, Vogt, Deborah R., Hemkens, Lars G., , Zanchi, Davide, Erlanger, Tobias E., Christ-Crain, Mirjam, & Winzeler, Bettina. (2023). Glucagon-like peptide-1 analogues: a new way to quit smoking? (SKIP)—a structured summary of a study protocol for a randomized controlled study. Trials, 24(1). https://doi.org/10.1186/s13063-023-07164-9
Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé M., Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas J., Rauch, Andri, Günthard, Huldrych F., Koller, Michael T., Trkola, Alexandra, Epp, Selina, Amstutz, Alain, et al. (2023). Antibody Response After the Third SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients and People Living With HIV (COVERALL-2). Open Forum Infectious Diseases, 10(11). https://doi.org/10.1093/ofid/ofad536
, Schroter, Sara, & Briel, Matthias. (2023). Guidance needed: where should randomized studies which do not assess a health outcome be registered? Journal of Clinical Epidemiology, 161, 183–184. https://doi.org/10.1016/j.jclinepi.2023.07.016
Schlussel MM, Sharp MK, de Beyer JA, Kirtley S, Logullo P, Dhiman P, MacCarthy A, Koroleva A, , Bullock GS, Moher D, & Collins GS. (2023). Reporting guidelines used varying methodology to develop recommendations. Journal of Clinical Epidemiology, 159, 246–256. https://doi.org/10.1016/j.jclinepi.2023.03.018
, Mann, Erika, Schönenberger, Christof M., Mellor, Katie, Griessbach, Alexandra N., Dhiman, Paula, Gandhi, Pooja, Lohner, Szimonetta, Agarwal, Arnav, Odutayo, Ayodele, Puebla, Iratxe, Clark, Alejandra, Chan, An-Wen, Schlussel, Michael M., Ravaud, Philippe, Moher, David, Briel, Matthias, Boutron, Isabelle, Schroter, Sara, & Hopewell, Sally. (2023). Reminding Peer Reviewers of Reporting Guideline Items to Improve Completeness in Published Articles: Primary Results of 2 Randomized Trials. JAMA Network Open, 6(6). https://doi.org/10.1001/jamanetworkopen.2023.17651
Amstutz, Alain, , Mentré, France, Rueegg, Corina Silvia, Belhadi, Drifa, Assoumou, Lambert, Burdet, Charles, Murthy, Srinivas, Dodd, Lori Elizabeth, Wang, Yeming, Tikkinen, Kari A O, Ader, Florence, Hites, Maya, Bouscambert, Maude, Trabaud, Mary Anne, Fralick, Mike, Lee, Todd C, Pinto, Ruxandra, Barratt-Due, Andreas, et al. (2023). Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials. The Lancet Respiratory Medicine, 11(5), 453–464. https://doi.org/10.1016/s2213-2600(22)00528-8
Dhiman P, Ma J, Andaur Navarro CL, , Bullock G, Damen JAA, Hooft L, Kirtley S, Riley RD, Van Calster B, Moons KGM, & Collins GS. (2023). Overinterpretation of findings in machine learning prediction model studies in oncology: a systematic review. Journal of Clinical Epidemiology, 157, 120–133. https://doi.org/10.1016/j.jclinepi.2023.03.012
Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé M., Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas J., Rauch, Andri, Günthard, Huldrych F., Koller, Michael T., Trkola, Alexandra, Epp, Selina, Amstutz, Alain, et al. (2023). Antibody Response After Third Vaccination With mRNA-1273 or BNT162b2: Extension of a Randomized Controlled SARS-CoV-2 Noninferiority Vaccine Trial in Patients With Different Levels of Immunosuppression (COVERALL-2). Open Forum Infectious Diseases, 10(4). https://doi.org/10.1093/ofid/ofad150
Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Vogt, Deborah R., Hemkens, Lars G., , Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., Christ-Crain, Mirjam, & Winzeler, Bettina. (2023). Effect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial. eClinicalMedicine, 57. https://doi.org/10.1016/j.eclinm.2023.101865
Lengsfeld, Sophia, Burkard, Thilo, Meienberg, Andrea, Jeanloz, Nica, Vukajlovic, Tanja, Bologna, Katja, Steinmetz, Michelle, Bathelt, Cemile, Sailer, Clara O., Vogt, Deborah R., Hemkens, Lars G., , Urwyler, Sandrine A., Kühne, Jill, Baur, Fabienne, Lutz, Linda N., Erlanger, Tobias E., Christ-Crain, Mirjam, & Winzeler, Bettina. (2023). Effect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial [Journal-article]. eClinicalMedicine, 57, 101865. https://doi.org/10.1016/j.eclinm.2023.101865
Dhiman P, Ma J, Andaur Navarro CL, , Bullock G, Damen JAA, Hooft L, Kirtley S, Riley RD, Van Calster B, Moons KGM, & Collins GS. (2022). Methodological conduct of prognostic prediction models developed using machine learning in oncology: a systematic review. BMC Medical Research Methodology, 22(1), 101. https://doi.org/10.1186/s12874-022-01577-x
Gloy, Viktoria, , Griessbach, Alexandra, Taji Heravi, Ala, Schulz, Alexandra, Fabbro, Thomas, Magnus, Christiane Pauli, McLennan, Stuart, Bertram, Wendy, & Briel, Matthias. (2022). Scoping review and characteristics of publicly available checklists for assessing clinical trial feasibility [Journal-article]. BMC Medical Research Methodology, 22(1). https://doi.org/10.1186/s12874-022-01617-6
Kusejko, Katharina, Chammartin, Frédérique, Smith, Daniel, Odermatt, Marc, Schuhmacher, Julian, Koller, Michael, Günthard, Huldrych F., Briel, Matthias, Bucher, Heiner C., , Abela, I., Aebi-Popp, K., Anagnostopoulos, A., Battegay, M., Bernasconi, E., Braun, D.L., Bucher, Heiner C., Calmy, A., Cavassini, M., et al. (2022). Developing and testing a Corona VaccinE tRiAL pLatform (COVERALL) to study Covid-19 vaccine response in immunocompromised patients. BMC Infectious Diseases, 22(1). https://doi.org/10.1186/s12879-022-07621-x
, Odutayo A, Peckham N, Ooms A, Stokes JR, Saccilotto R, Gryaznov D, von Niederhäusern B, Copsey B, Altman DG, Briel M, & Hopewell S. (2022). A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study. Trials, 23(1), 601. https://doi.org/10.1186/s13063-022-06516-1
Schönenberger, Christof Manuel, Griessbach, Alexandra, Taji Heravi, Ala, Gryaznov, Dmitry, Gloy, Viktoria L., Lohner, Szimonetta, Klatte, Katharina, Ghosh, Nilabh, Lee, Hopin, Mansouri, Anita, Marian, Ioana R., Saccilotto, Ramon, Nury, Edris, Busse, Jason W., von Niederhäusern, Belinda, Mertz, Dominik, Blümle, Anette, Odutayo, Ayodele, Hopewell, Sally, et al. (2022). A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols [Journal-article]. Journal of Clinical Epidemiology, 149, 45–52. https://doi.org/10.1016/j.jclinepi.2022.05.014
Schönenberger CM, Griessbach A, Taji Heravi A, Gryaznov D, Gloy VL, Lohner S, Klatte K, Ghosh N, Lee H, Mansouri A, Marian IR, Saccilotto R, Nury E, Busse JW, von Niederhäusern B, Mertz D, Blümle A, Odutayo A, Hopewell S, et al. (2022). A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols. Journal of Clinical Epidemiology, 149, 45–52. https://doi.org/10.1016/j.jclinepi.2022.05.014
Chammartin F, Kusejko K, Pasin C, Trkola A, Briel M, Amico P, Stoekle MP, Eichenberger AL, Hasse B, Braun DL, Schuurmans MM, Müller TF, Tamm M, Mueller NJ, Rauch A, Koller MT, Günthard HF, Bucher HC, , et al. (2022). Determinants of antibody response to severe acute respiratory syndrome coronavirus 2 mRNA vaccines in people with HIV. Aids, 36(10), 1465–1468. https://doi.org/10.1097/QAD.0000000000003246
Dhiman P, Ma J, Andaur Navarro CL, , Bullock G, Damen JAA, Hooft L, Kirtley S, Riley RD, Van Calster B, Moons KGM, & Collins GS. (2022). Risk of bias of prognostic models developed using machine learning: a systematic review in oncology. Diagnostic and Prognostic Research, 6(1), 13. https://doi.org/10.1186/s41512-022-00126-w
, Chammartin, Frédérique, Abela, Irene A, Amico, Patrizia, Stoeckle, Marcel P, Eichenberger, Anna L, Hasse, Barbara, Braun, Dominique L, Schuurmans, Macé M, Müller, Thomas F, Tamm, Michael, Audigé, Annette, Mueller, Nicolas J, Rauch, Andri, Günthard, Huldrych F, Koller, Michael T, Trkola, Alexandra, Briel, Matthias, Kusejko, Katharina, et al. (2022). Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial [Journal-article]. Clinical Infectious Diseases, 75(1), E585–E593. https://doi.org/10.1093/cid/ciac169
, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé, Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas, Rauch, Andri, Günthard, Huldrych F., Koller, Michael, Trkola, Alexandra, Briel, Matthias, Kusejko, Katharina, et al. (2022). Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial. Clinical Infectious Diseases, 75(1), E585–E593. https://doi.org/10.1093/cid/ciac169
Gryaznov, D., von Niederhäusern, B., , Kasenda, B., Ojeda-Ruiz, E., Blümle, A., Schandelmaier, S., Mertz, D., Odutayo, A., Tomonaga, Y., Amstutz, A., Pauli-Magnus, C., Gloy, V., Lohner, S., Bischoff, K., Wollmann, K., Rehner, L., Meerpohl, J. J., Nordmann, A., et al. (2022). Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE). BMJ Open, 12(5), e053417. https://doi.org/10.1136/bmjopen-2021-053417
, Gryaznov, Dmitry, Busse, Jason W., Gloy, Viktoria L., Lohner, Szimonetta, Klatte, Katharina, Taji Heravi, Ala, Ghosh, Nilabh, Lee, Hopin, Mansouri, Anita, Marian, Ioana R., Saccilotto, Ramon, Nury, Edris, Kasenda, Benjamin, Ojeda–Ruiz, Elena, Schandelmaier, Stefan, Tomonaga, Yuki, Amstutz, Alain, Pauli–Magnus, Christiane, et al. (2022). Nonregistration, discontinuation, and nonpublication of randomized trials: a repeated metaresearch analysis. PLoS Medicine, 19(4). https://doi.org/10.1371/journal.pmed.1003980
, Chammartin F, Smith D, Stoeckle MP, Amico P, Eichenberger AL, Hasse B, Schuurmans MM, Müller T, Tamm M, Dickenmann M, Abela IA, Trkola A, Hirsch HH, Manuel O, Cavassini M, Hemkens LG, Briel M, Mueller NJ, et al. (2021). A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®. Trials, 22(1), 724. https://doi.org/10.1186/s13063-021-05664-0
Dhiman P, Ma J, Navarro CA, , Bullock G, Damen JA, Kirtley S, Hooft L, Riley RD, Van Calster B, Moons KGM, & Collins GS. (2021). Reporting of prognostic clinical prediction models based on machine learning methods in oncology needs to be improved. Journal of Clinical Epidemiology, 138, 60–72. https://doi.org/10.1016/j.jclinepi.2021.06.024
Lohner, Szimonetta, Gryaznov, Dmitry, von Niederhäusern, Belinda, , Kasenda, Benjamin, Ojeda-Ruiz, Elena, Schandelmaier, Stefan, Mertz, Dominik, Odutayo, Ayodele, Tomonaga, Yuki, Amstutz, Alain, Pauli-Magnus, Christiane, Gloy, Viktoria, Bischoff, Karin, Wollmann, Katharina, Rehner, Laura, Meerpohl, Joerg J., Nordmann, Alain, Klatte, Katharina, et al. (2021). Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: A repeated cross-sectional study. Journal of Clinical Epidemiology, 139, 340–349. https://doi.org/10.1016/j.jclinepi.2021.05.011
, Gloy, V. L., Klatte, K., Gryaznov, D., Taji Heravi, A., Ghosh, N., Marian, I. R., Lee, H., Mansouri, A., Lohner, S., Saccilotto, R., Nury, E., Chan, A. W., Blümle, A., Odutayo, A., Hopewell, S., & Briel, M. (2021). Reliability of trial information across registries for trials with multiple registrations: a systematic review. JAMA Netw Open, 4(11), e2128898. https://doi.org/10.1001/jamanetworkopen.2021.28898
Merlo C, Essig S, Brancati-Badarau DO, Leuppi JD, , Erlanger TE, Hemkens L.G., & Zeller A. (2020). Oral corticosteroids for post-infectious cough in adults: study protocol for a double-blind randomized placebo-controlled trial in Swiss family practices (OSPIC trial). Trials, 21(1), 949. https://doi.org/10.1186/s13063-020-04848-4
. (2020). Adequate reporting of the sample size calculation in surgical randomized controlled trials. Surgery (United States), 167(5), 812–814. https://doi.org/10.1016/j.surg.2019.10.011
, Schroter S, Briel M, Moher D, Puebla I, Clark A, Maia Schlüssel M, Ravaud P, Boutron I, & Hopewell S. (2020). Impact of a short version of the CONSORT checklist for peer reviewers to improve the reporting of randomised controlled trials published in biomedical journals: study protocol for a randomised controlled trial. BMJ Open, 10(3), e035114. https://doi.org/10.1136/bmjopen-2019-035114
Gryaznov, D., Odutayo, A., von Niederhausern, B., , Kasenda, B., Ojeda-Ruiz, E., Blumle, A., Schandelmaier, S., Mertz, D., Tomonaga, Y., Amstutz, A., Pauli-Magnus, C., Gloy, V., Bischoff, K., Wollmann, K., Rehner, L., Lohner, S., Meerpohl, J. J., Nordmann, A., et al. (2020). Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects. Trials, 21(1), 896. https://doi.org/10.1186/s13063-020-04808-y
Janiaud P, Axfors C, Van’t Hooft J, Saccilotto R, Agarwal A, Appenzeller-Herzog C, Contopoulos-Ioannidis DG, Danchev V, Dirnagl U, Ewald H, Gartlehner G, Goodman SN, Haber NA, Ioannidis AD, Ioannidis JPA, Lythgoe MP, Ma W, Macleod M, Malički M, et al. (2020). The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days. F1000Research, 9, 1193. https://doi.org/10.12688/f1000research.26707.1
Kasenda, Benjamin, Liu, Junhao, Jiang, Yu, Gajewski, Byron, Wu, Cen, von Elm, Erik, Schandelmaier, Stefan, Moffa, Giusi, Trelle, Sven, Schmitt, Andreas Michael, Herbrand, Amanda K., Gloy, Viktoria, , Hopewell, Sally, Hemkens, Lars G., Sluka, Constantin, McGill, Kris, Meade, Maureen, Cook, Deborah, et al. (2020). Prediction of RECRUITment In Randomized Clinical Trials (RECRUIT-IT) - Rationale and Design for an International Collaborative Study. Trials, 21(1), 731. https://doi.org/10.1186/s13063-020-04666-8
Ladanie, Aviv, Schmitt, Andreas M., , Naudet, Florian, Agarwal, Arnav, Pereira, Tiago V., Sclafani, Francesco, Herbrand, Amanda K., Briel, Matthias, Martin-Liberal, Juan, Schmid, Thomas, Ewald, Hannah, Ioannidis, John P. A., Bucher, Heiner C., Kasenda, Benjamin, & Hemkens, Lars G. (2020). Clinical trial evidence supporting US Food and Drug Administration approval of novel cancer therapies between 2000 and 2016. Jama Network Open, 3(11), e2024406. https://doi.org/10.1001/jamanetworkopen.2020.24406
Odutayo A, Gryaznov D, Copsey B, Monk P, , Roberts C, Vadher K, Dutton P, Briel M, Hopewell S, Altman D.G., & ASPIRE study group . (2020). Design, analysis and reporting of multi-arm trials and strategies to address multiple testing. International Journal of Epidemiology, 49(3), 968–978. https://doi.org/10.1093/ije/dyaa026
Vazquez-Montes MDLA, Debray TPA, Taylor KS, , Jones N, Collins GS, Hobbs FDRR, Magriplis E, Maruri-Aguilar H, Moons KGM, Parissis J, Perera R, Roberts N, Taylor CJ, Kadoglou NPE, Trivella M, & proBHF group. (2020). UMBRELLA protocol: systematic reviews of multivariable biomarker prognostic models developed to predict clinical outcomes in patients with heart failure. Diagnostic and Prognostic Research, 4, 13. https://doi.org/10.1186/s41512-020-00081-4
Briel M, , von Elm E, & Gloy V. (2019). Comparison of randomized controlled trials discontinued or revised for poor recruitment and completed trials with the same research question: A matched qualitative study. Trials, 20(1), 800. https://doi.org/10.1186/s13063-019-3957-4
Hafner P, Bonati U, Klein A, Rubino D, Gocheva V, Schmidt S, Schroeder J, Bernert G, Laugel V, Steinlin M, Capone A, Gloor M, Bieri O, Hemkens LG, , Zumbrunn T, Gueven N, & Fischer D. (2019). Effect of combination l-citrulline and metformin treatment on motor function in patients with duchenne muscular dystrophy: A randomized clinical Trial. JAMA Network Open, 2(10), e1914171. https://doi.org/10.1001/jamanetworkopen.2019.14171
Engelter, Stefan, Hemkens, Lars G, , & Traenka, Christopher. (2019). Dopaminergic agents versus control for enhancing stroke recovery and rehabilitation. Cochrane Database of Systematic Reviews, 2019(8). https://doi.org/10.1002/14651858.CD013416
Glauser PM, Brosi P, , Käser SA, Heigl A, Rosenberg R, & Maurer CA. (2019). Prophylactic Intraperitoneal Onlay Mesh Following Midline Laparotomy-Long-Term Results of a Randomized Controlled Trial. World Journal of Surgery, 43(7), 1669–1675. https://doi.org/10.1007/s00268-019-04964-6
Glauser PM, Brosi P, , Käser SA, Heigl A, Rosenberg R, & Maurer CA. (2019). Erratum: Correction to: Prophylactic Intraperitoneal Onlay Mesh Following Midline Laparotomy-Long-Term Results of a Randomized Controlled Trial (World journal of surgery (2019) 43 7 (1669-1675)). World Journal of Surgery, 43(7), 1676. https://doi.org/10.1007/s00268-019-04979-z
Ladanie, Aviv, , Briel, Matthias, Sclafani, Francesco, Bucher, Heiner C., Agarwal, Arnav, Ioannidis, John P. A., Pereira, Tiago V., Kasenda, Benjamin, & Hemkens, Lars G. (2019). Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies. Journal of Clinical Epidemiology, 114, 49–59. https://doi.org/10.1016/j.jclinepi.2019.05.033
, Schur, Nadine, Gryaznov, Dmitry, von Niederhäusern, Belinda, Hemkens, Lars G., Schandelmaier, Stefan, Amstutz, Alain, Kasenda, Benjamin, Pauli-Magnus, Christiane, Ojeda-Ruiz, Elena, Tomonaga, Yuki, McCord, Kimberly, Nordmann, Alain, von Elm, Erik, Briel, Matthias, Schwenkglenks, Matthias, & a collaboration of the Marta Aspire Study Groups,. (2019). Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss human research legislation. PLoS ONE, 14(1), e0210669. https://doi.org/10.1371/journal.pone.0210669
Flükiger J, Hollinger A, , Meier V, Tontsch J, Zehnder T, & Siegemund M. (2018). Dexmedetomidine in prevention and treatment of postoperative and intensive care unit delirium: a systematic review and meta-analysis. Annals of Intensive Care, 8(1), 92. https://doi.org/10.1186/s13613-018-0437-z
Brosi P, Glauser PM, , Käser SA, & Maurer CA. (2018). Prophylactic Intraperitoneal Onlay Mesh Reinforcement Reduces the Risk of Incisional Hernia, Two-Year Results of a Randomized Clinical Trial. World Journal of Surgery, 42(6), 1687–1694. https://doi.org/10.1007/s00268-017-4363-2
, von Niederhäusern, Belinda, Schur, Nadine, Hemkens, Lars G., Fürst, Thomas, Bhatnagar, Neera, Alturki, Reem, Agarwal, Arnav, Kasenda, Benjamin, Pauli-Magnus, Christiane, Schwenkglenks, Matthias, Briel, Matthias, & Making Randomized Trials Affordable Group,. (2018). Systematic review on costs and resource use of randomized clinical trials shows a lack of transparent and comprehensive data. Journal of Clinical Epidemiology, 96, 1–11. https://doi.org/10.1016/j.jclinepi.2017.12.018
Mechera R, Schuster T, Rosenberg R, & . (2017). Lymph node yield after rectal resection in patients treated with neoadjuvant radiation for rectal cancer: A systematic review and meta-analysis. European Journal of Cancer, 72, 84–94. https://doi.org/10.1016/j.ejca.2016.10.031
. (2017). Blinding in Surgical Randomized Clinical Trials in 2015. Annals of Surgery, 266(1), 21–22. https://doi.org/10.1097/SLA.0000000000002242
Bogoch, Isaac I., Andrews, Jason R., , Utzinger, Juerg, Ame, Shaali M., Ali, Said M., & Keiser, Jennifer. (2013). Short report: Mobile phone microscopy for the diagnosis of soil-transmitted helminth infections: A proof-of-concept study. American Journal of Tropical Medicine and Hygiene, 88(4), 626–629. https://doi.org/10.4269/ajtmh.12-0742
Bogoch, Isaac I, Andrews, Jason R, , Utzinger, Jürg, Ame, Shaali M, Ali, Said M, & Keiser, Jennifer. (2013). Mobile phone microscopy for the diagnosis of soil-transmitted helminth infections : a Proof-of-Concept Study. American Journal of Tropical Medicine and Hygiene, 88(4), 9–626. https://doi.org/10.4269/ajtmh.12-0742
Other Publications
Griessbach, A., Chiaborelli, M., Ehrlich, K., Grossmann, R., De Medina Redondo, M., Fayet, A., Maier, R., Trelle, S., Gayet-Ageron, A., Ceschi, A., Speich, B., & Briel, M. (2025). Clinical trial budgeting approaches in Switzerland—a meta-research study [Journal-article]. Trials, 26(1). https://doi.org/10.1186/s13063-025-08855-1
Ramirez, H. W., Chiaborelli, M., Schönenberger, C. M., Mellor, K., Griessbach, A. N., Dhiman, P., Gandhi, P., Lohner, S., Agarwal, A., Odutayo, A., Schlussel, M. M., Ravaud, P., Moher, D., Briel, M., Boutron, I., Hopewell, S., Schroter, S., & Speich, B. (2025). Do peer reviewers comment on reporting items as instructed by the journal? A secondary analysis of two randomized trials [Journal-article]. Journal of Clinical Epidemiology, 183, 111818. https://doi.org/10.1016/j.jclinepi.2025.111818
Amstutz, A., Schandelmaier, S., Ewald, H., Speich, B., Schwenke, J. M., Schönenberger, C. M., Schobinger, S., Agoritsas, T., Tomashek, K. M., Nayak, S., Makowski, M., Morales-Ortega, A., Bernal-Bello, D., Pomponio, G., Ferrarini, A., Ghazaeian, M., Hall, F., Bond, S., García-Morales, M. T., et al. (2025). Effects of Janus kinase inhibitors in adults admitted to hospital due to COVID-19: a systematic review and individual participant data meta-analysis of randomised clinical trials [Journal-article]. The Lancet Respiratory Medicine, 13(6), 530–544. https://doi.org/10.1016/S2213-2600(25)00055-4
Gloy, V., , Griessbach, A., Taji Heravi, A., Schulz, A., Fabbro, T., Magnus, C. P., McLennan, S., Bertram, W., & Briel, M. (2022). Scoping review and characteristics of publicly available checklists for assessing clinical trial feasibility. BMC Med Res Methodol, 22(1), 142. https://doi.org/10.1186/s12874-022-01617-6
Amstutz, A., Speich, B., Mentré, F., Rueegg, C. S., Belhadi, D., Assoumou, L., Burdet, C., Murthy, S., Dodd, L. E., Wang, Y., Tikkinen, K., Ader, F., Hites, M., Bouscambert-Duchamp, M., Trabaud, M.-A., Fralick, M., Lee, T. C., Pinto, R., Barratt-Due, A., et al. (2022). Effects of Remdesivir in Hospitalized Patients with COVID-19: Systematic Review and Individual Patient Data Meta-Analysis of Randomized Clinical Trials [Journal-article]. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.4244759
Olliaro, P. L., Vaillant, M. T., Diawara, A., , Albonico, M., Utzinger, J., & Keiser, J. (2022). Egg excretion indicators for the measurement of soil-transmitted helminth response to treatment. PLoS Negl Trop Dis, 16(8), e0010593. https://doi.org/10.1371/journal.pntd.0010593
, Logullo, P., Deuster, S., Marian, I. R., Moschandreas, J., Taji Heravi, A., Gloy, V., Briel, M., Hopewell, S., & Making Randomized Trials Affordable Group. (2021). A meta-research study revealed several challenges in obtaining placebos for investigator-initiated drug trials. J Clin Epidemiol, 131, 70–78. https://doi.org/10.1016/j.jclinepi.2020.11.007
Janiaud, Perrine, Axfors, Cathrine, Van’t Hooft, Janneke, Saccilotto, Ramon, Agarwal, Arnav, Appenzeller-Herzog, Christian, Contopoulos-Ioannidis, Despina G., Danchev, Valentin, Dirnagl, Ulrich, Ewald, Hannah, Gartlehner, Gerald, Goodman, Steven N., Haber, Noah A., Ioannidis, Angeliki Diotima, Ioannidis, John P. A., Lythgoe, Mark P., Ma, Wenyan, Macleod, Malcolm, Malički, Mario, et al. (2020). The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days. F1000Research, 9, 1193. https://doi.org/10.12688/f1000research.26707.1
Moser, Wendelin, Keiser, Jennifer, , Sayasone, Somphou, Knopp, Stefanie, & Hattendorf, Jan. (2020). One mean to rule them all? The arithmetic mean based egg reduction rate can be misleading when estimating anthelminthic drug efficacy in clinical trials. PLoS Neglected Tropical Diseases, 14(4), e0008185. https://doi.org/10.1371/journal.pntd.0008185
, Gloy, Viktoria, Schur, Nadine, Ewald, Hannah, Hemkens, Lars G., Schwenkglenks, Matthias, Briel, Matthias, & MAking Randomized Trials Affordable Group. (2020). A scoping review shows that several nonvalidated budget planning tools for randomized trials are available. Journal of Clinical Epidemiology, 117, 9–19. https://doi.org/10.1016/j.jclinepi.2019.09.009
Bogoch, Isaac I., , Lo, Nathan C., Moser, Wendelin, Croll, David, Ali, Said M., Ame, Shaali M., Utzinger, Jürg, Andrews, Jason R., & Keiser, Jennifer. (2019). Clinical evaluation for morbidity associated with soil-transmitted helminth infection in school-age children on Pemba Island, Tanzania. PLoS Neglected Tropical Diseases, 13(7), e0007581. https://doi.org/10.1371/journal.pntd.0007581
Ewald, Hannah, , Ladanie, Aviv, Bucher, Heiner C., Ioannidis, John P. A., & Hemkens, Lars G. (2019). Marginal structural models and other analyses allow multiple estimates of treatment effects in randomized clinical trials: Meta-epidemiological analysis. Journal of clinical epidemiology, 107, 12–26. https://doi.org/10.1016/j.jclinepi.2018.11.001
Mc Cord, Kimberly A., Ewald, Hannah, Ladanie, Aviv, Briel, Matthias, , Bucher, Heiner C., Hemkens, Lars G., & RCD for RCTs initiative and the Making Randomized Trials More Af. (2019). Current use and costs of electronic health records for clinical trial research : a descriptive study. CMAJ open, 7(1), E23–E32. https://doi.org/10.9778/cmajo.20180096
, , Bausch, Kathrin, Roth, Jan A., Hemkens, Lars G., Ewald, Hannah, Vogt, Deborah R., Bruni, Nicole, Deuster, Stefanie, Seifert, Hans-H., & Widmer, Andreas F. (2019). Single-dose versus 3-day cotrimoxazole prophylaxis in transurethral resection or greenlight laser vaporisation of the prostate: study protocol for a multicentre randomised placebo controlled non-inferiority trial (CITrUS trial). Trials, 20(1), 142. https://doi.org/10.1186/s13063-019-3237-3
, Mc Cord, Kimberly A., Agarwal, Arnav, Gloy, Viktoria, Gryaznov, Dmitry, Moffa, Giusi, Hopewell, Sally, & Briel, Matthias. (2019). Reporting Quality of Journal Abstracts for Surgical Randomized Controlled Trials Before and After the Implementation of the CONSORT Extension for Abstracts. World Journal of Surgery, 43(10), 2371–2378. https://doi.org/10.1007/s00268-019-05064-1
Palmeirim, Marta S., Hürlimann, Eveline, Knopp, Stefanie, , Belizario, Vicente, Joseph, Serene A., Vaillant, Michel, Olliaro, Piero, & Keiser, Jennifer. (2018). Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths : a systematic review, meta-analysis and individual patient data analysis. PLoS Neglected Tropical Diseases, 12(4), e0006458. https://doi.org/10.1371/journal.pntd.0006458
, Thomer, Anja, Aghlmandi, Soheila, Ewald, Hannah, Zeller, Andreas, & Hemkens, Lars G. (2018). Treatments for subacute cough in primary care : systematic review and meta-analyses of randomised clinical trials. The British journal of general practice, 68(675), e694–e702. https://doi.org/10.3399/bjgp18x698885
Barda, Beatrice, Albonico, Marco, Buonfrate, Dora, Ame, Shaali M., Ali, Said, , & Keiser, Jennifer. (2017). Side benefits of mass drug administration for lymphatic filariasis on Strongyloides stercoralis prevalence on Pemba Island, Tanzania. American Journal of Tropical Medicine and Hygiene, 97(3), 681–683. https://doi.org/10.4269/ajtmh.17-0050
, Croll, David, Fürst, Thomas, Utzinger, Jürg, & Keiser, Jennifer. (2016). Effect of sanitation and water treatment on intestinal protozoa infection : a systematic review and meta-analysis. The Lancet Infectious Diseases, 16(1), 87–99. https://doi.org/10.1016/s1473-3099(15)00349-7
, Moser, Wendelin, Ali, Said M, Ame, Shaali M, Albonico, Marco, Hattendorf, Jan, & Keiser, Jennifer. (2016). Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole, albendazole-oxantel pamoate and mebendazole. Parasites and Vectors, 9, 123. https://doi.org/10.1186/s13071-016-1406-8
Barda, Beatrice, Albonico, Marco, Ianniello, Davide, Ame, Shaali M., Keiser, Jennifer, , Rinaldi, Laura, Cringoli, Giuseppe, Burioni, Roberto, Montresor, Antonio, & Utzinger, Juerg. (2015). How long can stool samples be fixed for an accurate diagnosis of soil-transmitted helminth infection using mini-FLOTAC? PLoS neglected tropical diseases, 9(4), e0003698. https://doi.org/10.1371/journal.pntd.0003698
Moser, Wendelin, Ali, Said M, Ame, Shaali M, , Puchkov, Maxim, Huwyler, Jörg, Albonico, Marco, Hattendorf, Jan, & Keiser, Jennifer. (2015). Efficacy and safety of oxantel pamoate in school-aged children infected with Trichuris trichiura on Pemba Island, Tanzania: a parallel, randomised, controlled, dose-ranging study. The Lancet Infectious Diseases, 16(1), 53–60. https://doi.org/10.1016/s1473-3099(15)00271-6
, Ali, Said M, Ame, Shaali M, Albonico, Marco, Utzinger, Jürg, & Keiser, Jennifer. (2015). Quality control in the diagnosis of Trichuris trichiura and Ascaris lumbricoides using the Kato-Katz technique : experience from three randomised controlled trials. Parasites and Vectors, 8(82), 82. https://doi.org/10.1186/s13071-015-0702-z
, Ali, Said M, Ame, Shaali M, Bogoch, Isaac I, Alles, Rainer, Huwyler, Jörg, Albonico, Marco, Hattendorf, Jan, Utzinger, Jürg, & Keiser, Jennifer. (2015). Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infection : a four-arm, randomised controlled trial. The Lancet Infectious Diseases, 15(3), 84–277. https://doi.org/10.1016/s1473-3099(14)71050-3
Bogoch, Isaac I, Andrews, Jason R, , Ame, Shaali M, Ali, Said M, Stothard, J Russell, Utzinger, Jürg, & Keiser, Jennifer. (2014). Quantitative evaluation of a handheld light microscope for field diagnosis of soil-transmitted helminth infection. American Journal of Tropical Medicine and Hygiene, 91(6), 41–1138. https://doi.org/10.4269/ajtmh.14-0253
Bogoch, Isaac I, Coulibaly, Jean T, Andrews, Jason R, , Keiser, Jennifer, Stothard, J Russell, N’goran, Eliézer K, & Utzinger, Jürg. (2014). Evaluation of portable microscopic devices for the diagnosis of Schistosoma and soil-transmitted helminth infection. Parasitology, 141(14), 8–1811. https://doi.org/10.1017/s0031182014000432
Keiser, J., , & Utzinger, J. (2014). The authors reply : Yasukawa K. comment to “Oxantel pamoate-albendazole for Trichuris trichiura infection” [Review of The authors reply : Yasukawa K. comment to “Oxantel pamoate-albendazole for Trichuris trichiura infection”]. The New England Journal of Medicine, 370, Article 20. https://doi.org/10.1056/nejmc1403068
Panic, Gordana, Duthaler, Urs, , & Keiser, Jennifer. (2014). Repurposing drugs for the treatment and control of helminth infections. International Journal of Parasitology : Drugs and Drug Resistance, 4(3), 185–200. https://doi.org/10.1016/j.ijpddr.2014.07.002
, Ame, Shaali M, Ali, Said M, Alles, Rainer, Huwyler, Jörg, Hattendorf, Jan, Utzinger, Jürg, Albonico, Marco, & Keiser, Jennifer. (2014). Oxantel pamoate-albendazole for Trichuris trichiura infection. The New England Journal of Medicine, 370(7), 20–610. https://doi.org/10.1056/nejmoa1301956
, Utzinger, J, Marti, H, Ame, S M, Ali, S M, Albonico, M, & Keiser, J. (2014). Comparison of the Kato-Katz method and ether-concentration technique for the diagnosis of soil-transmitted helminth infections in the framework of a randomised controlled trial. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 33(5), 22–815. https://doi.org/10.1007/s10096-013-2019-1
Alles, R., Puchkov, M., Jablonski, C., , Keiser, J., & Huwyler, J. (2013). Development of oxantel tablets for pediatric clinical studies : a technical note. Journal of Drug Delivery Science and Technology, 23(6), 623–625. https://doi.org/10.1016/s1773-2247(13)50095-5
Keiser, Jennifer, Tritten, Lucienne, Silbereisen, Angelika, , Adelfio, Roberto, & Vargas, Mireille. (2013). Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug. PLoS neglected tropical diseases, 7(3), e2119. https://doi.org/10.1371/journal.pntd.0002119
, Marti, Hanspeter, Ame, Shaali M, Ali, Said M, Bogoch, Isaac I, Utzinger, Jürg, Albonico, Marco, & Keiser, Jennifer. (2013). Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide. Parasites and Vectors, 6(3), 3. https://doi.org/10.1186/1756-3305-6-3
, Ame, Shaali M, Ali, Said M, Alles, Rainer, Hattendorf, Jan, Utzinger, Jürg, Albonico, Marco, & Keiser, Jennifer. (2012). Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection : a randomized controlled trial. PLoS Neglected Tropical Diseases, 6(6), e1685. https://doi.org/10.1371/journal.pntd.0001685
Ziegelbauer, Kathrin, , Mäusezahl, Daniel, Bos, Robert, Keiser, Jennifer, & Utzinger, Jürg. (2012). Effect of sanitation on soil-transmitted helminth infection : systematic review and meta-analysis [Review of Effect of sanitation on soil-transmitted helminth infection : systematic review and meta-analysis]. PLoS Medicine, 9, Article 1. https://doi.org/10.1371/journal.pmed.1001162
Becker, Soeren L., Lohourignon, Laurent K., , Rinaldi, Laura, Knopp, Stefanie, N’Goran, Eliezer K., Cringoli, Giuseppe, & Utzinger, Juerg. (2011). Comparison of the FLOTAC-400 dual technique and the Formalin-Ether Concentration Technique for the diagnosis of human intestinal protozoa infection. Journal of Clinical Microbiology, 49(6), 2183–2190. https://doi.org/10.1128/jcm.01035-10
Knopp, Stefanie, , Hattendorf, Jan, Rinaldi, Laura, Mohammed, Khalfan A, Khamis, I Simba, Mohammed, Alisa S, Albonico, Marco, Rollinson, David, Marti, Hanspeter, Cringoli, Giuseppe, & Utzinger, Jürg. (2011). Diagnostic accuracy of Kato-Katz and FLOTAC for assessing anthelmintic drug efficacy. PLoS Neglected Tropical Diseases, 5(4), e1036. https://doi.org/10.1371/journal.pntd.0001036
Knopp, S., Mohammed, K. A., , Hattendorf, J., Khamis, I. S., Khamis, A. N., Stothard, J. R., Rollinson, D., Marti, H., & Utzinger, J. (2010). Albendazole and mebendazole administered alone or in combination with Ivermectin against Trichuris trichiura: a randomized controlled trial. Clinical Infectious Diseases, 51(12), 8–1420. https://doi.org/10.1086/657310
, Knopp, Stefanie, Mohammed, Khalfan A, Khamis, I Simba, Rinaldi, Laura, Cringoli, Giuseppe, Rollinson, David, & Utzinger, Jürg. (2010). Comparative cost assessment of the Kato-Katz and FLOTAC techniques for soil-transmitted helminth diagnosis in epidemiological surveys. Parasites and Vectors, 3(71), 71. https://doi.org/10.1186/1756-3305-3-71
Supplemental Publications
Olliaro, P., Vaillant, M., Diawara, A., N’Goran, E. K., Ame, S., , Knopp, S., Steinmann, P., Yap, P., Zhou, X-N., Albonico, M., Utzinger, J., & Keiser, J. (2017). Egg excretion indicators for the measurement of soil-transmitted helminth response to treatment. 22, 47–48. WILEY.
Mechera, R., Schuster, T., Rosenberg, R., & (2017). Lymph node yield after rectal resection in patients treated with neoadjuvant radiation for rectal cancer: A systematic review and meta-analysis. 104, 5. WILEY.