Dr. Ricardo Jorge Bouça-Nova Coelho

Lischetti, U., Liang, C.-Y., Carrara, M., Coelho, R., Hanns, A., Lombardo, F., Dondi, A., Goetze, S., Hensler, M., Kurzeder, C., Montavon, C., Fucikova, J., Singer, F., Beerenwinkel, N., Beisel, C., Heinzelmann-Schwarz, V., & Jacob, F. (2025). Ovarian cancer metastasis to the human omentum disrupts organ homeostasis and induces fundamental tissue reprogramming [Journal-article]. Nature Communications. https://doi.org/10.1038/s41467-025-67557-z

Bollhagen, Alina, Whipman, James, Coelho, Ricardo, Heinzelmann-Schwarz, Viola, Jacob, Francis, & Bodenmiller, Bernd. (2025). High-resolution imaging mass cytometry to map subcellular structures. Nature Methods. https://doi.org/10.1038/s41592-025-02889-8

Miglino, Nicola, Toussaint, Nora C., Ring, Alexander, Bonilla, Ximena, Tusup, Marina, Gosztonyi, Benedict, Mehra, Tarun, Gut, Gabriele, Jacob, Francis, Chevrier, Stephane, Lehmann, Kjong-Van, Casanova, Ruben, Jacobs, Andrea, Sivapatham, Sujana, Boos, Laura, Rahimzadeh, Parisa, Schuerch, Manuel, Sobottka, Bettina, Chicherova, Natalia, et al. (2025). Feasibility of multiomics tumor profiling for guiding treatment of melanoma. Nature Medicine, 31, 2430–2441. https://doi.org/10.1038/s41591-025-03715-6

Casanova, Ruben, Xu, Shuhan, Bost, Pierre, Sivapatham, Sujana, Jacobs, Andrea, Engler, Stefanie, Aebersold, Rudolf, Ak, Melike, Al-Quaddoomi, Faisal S, Silvana, I Albert, Albinus, Jonas, Alborelli, Ilaria, Andani, Sonali, Attinger, Per-Olof, Bacac, Marina, Baumhoer, Daniel, Beck-Schimmer, Beatrice, Beerenwinkel, Niko, Beisel, Christian, et al. (2025). Standardization of Suspension and Imaging Mass Cytometry Single-Cell Readouts for Clinical Decision Making. Cytometry Part A, 107, 390–403. https://doi.org/10.1002/cyto.a.24940

Todorov, Tihomir Zh, Coelho, Ricardo, Jacob, Francis, Heinzelmann-Schwarz, Viola, Schibli, Roger, Béhé, Martin, Grünberg, Jürgen, & Grzmil, Michal. (2025). Phosphoproteomics Reveals L1CAM-Associated Signaling Networks in High-Grade Serous Ovarian Carcinoma: Implications for Radioresistance and Tumorigenesis. International Journal of Molecular Sciences, 26. https://doi.org/10.3390/ijms26104585

Zwimpfer, Tibor A., Heidinger, Martin, Coelho, Ricardo, Stiegeler, Nadja, Schwab, Fabienne D., Montavon, Céline, Eller, Ruth S., Maggi, Nadia, Loesch, Julie M., Vetter, Marcus, Lambertini, Matteo, Weber, Walter P., Kurzeder, Christian, & Heinzelmann-Schwarz, Viola. (2025). TP53 Mutations and Phosphatidylinositol 3-Kinase/AKT Pathway Alterations Are Key Determinants of Breast Cancer Outcome Independent of Subtype and Stage. JCO Precision Oncology, 9. https://doi.org/10.1200/PO-24-00767

Canário, Rita, Ribeiro, Ana Sofia, Morgado, Inês, Peixoto, Ana, Barbosa, Ana, Santos, Catarina, Mendes, Nuno, Lopes, Paula, Monteiro, Paula, Coelho, Ricardo, Jacob, Francis, Heinzelmann-Schwarz, Viola, Ricardo, Sara, Teixeira, Manuel R., Bartosch, Carla, & Paredes, Joana. (2025). P-cadherin overexpression is associated with early transformation of the Fallopian tube epithelium and aggressiveness of tubo-ovarian high-grade serous carcinoma. Virchows Archiv. https://doi.org/10.1007/s00428-025-04104-7

Wegmann, Rebekka, Bonilla, Ximena, Casanova, Ruben, Chevrier, Stéphane, Coelho, Ricardo, Esposito, Cinzia, Ficek-Pascual, Joanna, Goetze, Sandra, Gut, Gabriele, Jacob, Francis, Jacobs, Andrea, Kuipers, Jack, Lischetti, Ulrike, Mena, Julien, Milani, Emanuela S., Prummer, Michael, Del Castillo, Jacobo Sarabia, Singer, Franziska, Sivapatham, Sujana, et al. (2024). Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia [Journal-article]. Nature Communications , 15(1). https://doi.org/10.1038/s41467-024-53535-4

Labrosse, Kathrin B., Lombardo, Flavio C., Rimmer, Natalie, Núñez López, Mónica, Fedier, André, Heinzelmann-Schwarz, Viola, Coelho, Ricardo, & Jacob, Francis. (2024). Protocol for quantifying drug sensitivity in 3D patient-derived ovarian cancer models. STAR Protocols, 5(3). https://doi.org/10.1016/j.xpro.2024.103274

Coelho, Ricardo, Seashore-Ludlow, Brinton, Schütz, Sarah, Lombardo Christopher, Flavio, Moussaud-Lamodière, Elisabeth, Casanova, Ruben, Ficek-Pascual, Joanna, Labrosse Brunhilde, Kathrin, Lopez-Nunez, Monica, Rimmer, Natalie, Fedier, Andre, Lima, Renata, Montavon Sartorius, Céline, Kurzeder, Christian, Singer, Franziska, Bertolini, Anne, Rätsch, Gunnar, Bodenmiller, Bernd, Kallioniemi, Olli, et al. (2024). SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.01.24.576987

Rimmer, Natalie, Liang, Ching-Yeu, Coelho, Ricardo, Lopez, Monica Nunez, & Jacob, Francis. (2023). Generation of endogenously tagged E-cadherin cells using gene editing via non-homologous end joining. STAR Protocols, 4(2). https://doi.org/10.1016/j.xpro.2023.102305

Estermann, Manuela, Coelho, Ricardo, Jacob, Francis, Huang, Yen-Lin, Liang, Ching-Yeu, Faia-Torres, Ana Bela, Septiadi, Dedy, Drasler, Barbara, Karakocak, Bedia Begum, Dijkhoff, Irini Magdelina, Petri-Fink, Alke, Heinzelmann-Schwarz, Viola, & Rothen-Rutishauser, Barbara. (2023). A 3D multi-cellular tissue model of the human omentum to study the formation of ovarian cancer metastasis. Biomaterials, 294. https://doi.org/10.1016/j.biomaterials.2023.121996

Zwimpfer, Tibor A., Tal, Ori, Geissler, Franziska, Coelho, Ricardo, Rimmer, Natalie, Jacob, Francis, & Heinzelmann-Schwarz, Viola. (2023). Low grade serous ovarian cancer – A rare disease with increasing therapeutic options. Cancer Treatment Reviews, 112, 102497. https://doi.org/10.1016/j.ctrv.2022.102497

Dondi, A., Lischetti, U., Jacob, F., Singer, F., Borgsmüller, N., Coelho, R., Heinzelmann-Schwarz, V., Beisel, C., & Beerenwinkel, N. (2022, December 14). Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2022.12.12.520051

Coelho, Ricardo, Tozzi, Alessandra, Disler, Muriel, Lombardo, Flavio, Fedier, André, López, Mónica Núñez, Freuler, Florian, Jacob, Francis, & Heinzelmann-Schwarz, Viola. (2022). Overlapping gene dependencies for PARP inhibitors and carboplatin response identified by functional CRISPR-Cas9 screening in ovarian cancer. Cell Death and Disease, 13(10), 909. https://doi.org/10.1038/s41419-022-05347-x

Nunes, M., Silva, P. M. A., Coelho, R., Pinto, C., Resende, A., Bousbaa, H., Almeida, G. M., & Ricardo, S. (2022). Corrigendum: Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein(Front. Oncol., (2021), 11, (752127), 10.3389/fonc.2021.752127). Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.853608

Nunes, M., Pacheco, F., Coelho, R., Leitão, D., Ricardo, S., & David, L. (2022). Mesothelin Expression Is Not Associated with the Presence of Cancer Stem Cell Markers SOX2 and ALDH1 in Ovarian Cancer. International Journal of Molecular Sciences, 23(3). https://doi.org/10.3390/ijms23031016

Huang, Yen-Lin, Liang, Ching-Yeu, Ritz, Danilo, Coelho, Ricardo, Septiadi, Dedy, Estermann, Manuela, Cumin, Cécile, Rimmer, Natalie, Schötzau, Andreas, Núñez López, Mónica, Fedier, André, Konantz, Martina, Vlajnic, Tatjana, Calabrese, Diego, Lengerke, Claudia, David, Leonor, Rothen-Rutishauser, Barbara, Jacob, Francis, & Heinzelmann-Schwarz, Viola. (2020). Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis. eLife, 9, e59442. https://doi.org/10.7554/elife.59442

Coelho, R., Marcos-Silva, L., Ricardo, S., Ponte, F., Costa, A., Lopes, J. M., & David, L. (2018). Peritoneal dissemination of ovarian cancer: Role of MUC16-mesothelin interaction and implications for treatment. Expert Review of Anticancer Therapy, 18(2), 177–186. https://doi.org/10.1080/14737140.2018.1418326

Pereira, S. S., Máximo, V., Coelho, R., Batista, R., Soares, P., Guerreiro, S. G., Sobrinho-Simões, M., Monteiro, M. P., & Pignatelli, D. (2017). Telomerase and N-Cadherin Differential Importance in Adrenocortical Cancers and Adenomas. Journal of Cellular Biochemistry, 118(8), 2064–2071. https://doi.org/10.1002/jcb.25811

Ricardo, S., Marcos-Silva, L., Valente, C., Coelho, R., Gomes, R., & David, L. (2016). Mucins MUC16 and MUC1 are major carriers of SLea and SLex in borderline and malignant serous ovarian tumors. Virchows Archiv, 468(6), 715–722. https://doi.org/10.1007/s00428-016-1929-6

Pertega-Gomes, N., Felisbino, S., Massie, C. E., Vizcaino, J. R., Coelho, R., Sandi, C., Simoes-Sousa, S., Jurmeister, S., Ramos-Montoya, A., Asim, M., Tran, M., Oliveira, E., Lobo Da Cunha, A., Maximo, V., Baltazar, F., Neal, D. E., & Fryer, L. G. D. (2015). A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: A role for monocarboxylate transporters as metabolic targets for therapy. Journal of Pathology, 236(4), 517–530. https://doi.org/10.1002/path.4547

Vinagre, J., Almeida, A., Pópulo, H., Batista, R., Lyra, J., Pinto, V., Coelho, R., Celestino, R., Prazeres, H., Lima, L., Melo, M., Rocha, A. G. D., Preto, A., Castro, P., Castro, L., Pardal, F., Lopes, J. M., Santos, L. L., Reis, R. M., et al. (2013). Frequency of TERT promoter mutations in human cancers. Nature Communications, 4. https://doi.org/10.1038/ncomms3185