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Dr. Clémentine Le Magnen

Department of Biomedicine
Profiles & Affiliations

Selected Publications

Parmentier, R., Dolgos, R., Servant, R., Wang, J., Roma, L., Mevel, R., Bossi, D., Pueschel, H., Diamantopoulou, Z., Vlajnic, T., Stenner, F., Templeton, A. J., Seifert, H., Aceto, N., Theurillat, J.-P., Rentsch, C. A., Bubendorf, L., & Le Magnen, C. (2026). A modular patient-derived organoid–xenograft platform reveals molecular and clinical trajectories of prostate cancer progression [Posted-content]. openRxiv. https://doi.org/10.64898/2026.01.05.697006

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Dolgos, Robin, Parmentier, Romuald, Wang, Jing, Servant, Raphaëlle, Templeton, Arnoud J., Zellweger, Tobias, Lamb, Alastair D., Mertz, Kirsten D., Subotic, Svetozar, Vlajnic, Tatjana, Seifert, Helge, Mortezavi, Ashkan, Rentsch, Cyrill A., Bubendorf, Lukas, & Le Magnen, Clémentine. (2025). Single-cell analysis uncovers preserved prostate cancer lineages and universally altered pathways in Matrigel-free patient-derived organoids. Cell Reports, 44(10). https://doi.org/10.1016/j.celrep.2025.116352

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Garioni, Michele, Tschan, Viviane J., Blukacz, Lauriane, Nuciforo, Sandro, Parmentier, Romuald, Roma, Luca, Coto-Llerena, Mairene, Pueschel, Heike, Piscuoglio, Salvatore, Vlajnic, Tatjana, Stenner, Frank, Seifert, Hans-Helge, Rentsch, Cyrill A., Bubendorf, Lukas, & Le Magnen, Clémentine. (2023). Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer. Npj Precision Oncology, 7(1). https://doi.org/10.1038/s41698-023-00466-w

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Servant R, Garioni M, Vlajnic T, Blind M, Pueschel H, Müller DC, Zellweger T, Templeton AJ, Garofoli A, Maletti S, Piscuoglio S, Rubin MA, Seifert H, Rentsch CA, Bubendorf L, & Le Magnen C. (2021). Prostate cancer patient-derived organoids: detailed outcome from a prospective cohort of 81 clinical specimens. Journal of Pathology, 254(5), 543–555. https://doi.org/10.1002/path.5698

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Dutta, A., Le Magnen, C., Mitrofanova, A., Ouyang, X., Califano, A., & Abate-Shen, C. (2016). Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science, 352(6293), 1576–1580. https://doi.org/10.1126/science.aad9512

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