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PD Dr. Srinivas Madduri

Department of Biomedical Engineering
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Mehta, Viraj, Vilikkathala Sudhakaran, Sukanya, Nellore, Vijaykumar, Madduri, Srinivas, & Rath, Subha Narayan. (2024). 3D stem-like spheroids-on-a-chip for personalized combinatorial drug testing in oral cancer [Journal-article]. Journal of Nanobiotechnology, 22(1). https://doi.org/10.1186/s12951-024-02625-y

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Dogny, Clelia, André-Lévigne, Dominik, Kalbermatten, Daniel F., & Madduri, Srinivas. (2024). Therapeutic Potential and Challenges of Mesenchymal Stem Cell-Derived Exosomes for Peripheral Nerve Regeneration: A Systematic Review [Journal-article]. International Journal of Molecular Sciences, 25(12), 6489. https://doi.org/10.3390/ijms25126489

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Eseme, Ebai A., Remy, Katya, Mené, Blandine L., Walz, Solange N., Madduri, Srinivas, Oranges, Carlo M., & Kalbermatten, Daniel F. (2024). Sensory and pain outcomes of neurotized skin-grafted free gracilis muscle flaps for lower extremity reconstruction [Journal-article]. Journal of Plastic, Reconstructive & Aesthetic Surgery, 92, 216–224. https://doi.org/10.1016/j.bjps.2024.02.071

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André-Lévigne, Dominik, Pignel, Rodrigue, Boet, Sylvain, Jaquet, Vincent, Kalbermatten, Daniel F., & Madduri, Srinivas. (2024). Role of Oxygen and Its Radicals in Peripheral Nerve Regeneration: From Hypoxia to Physoxia to Hyperoxia [Journal-article]. International Journal of Molecular Sciences, 25(4), 2030. https://doi.org/10.3390/ijms25042030

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WALZ, SOLANGE N., MARTINEAU, JEROME, SCAMPA, MATTEO, MADDURI, SRINIVAS, KALBERMATTEN, DANIEL F., & ORANGES, CARLO M. (2024). Incidence Trends of Melanoma of the Lower Limbs and Hips in the United States: A Surveillance, Epidemiology, and End Results Analysis 2000-2019 [Journal-article]. Anticancer Research, 44(1), 239–247. https://doi.org/10.21873/anticanres.16807

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Fenelon, Mathilde, Galvez, Paul, Kalbermatten, Daniel, Scolozzi, Paolo, & Madduri, Srinivas. (2023). Emerging Strategies for the Biofabrication of Multilayer Composite Amniotic Membranes for Biomedical Applications [Journal-article]. International Journal of Molecular Sciences, 24(19), 14424. https://doi.org/10.3390/ijms241914424

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Solomevich, Sergey O., Oranges, Carlo M., Kalbermatten, Daniel F., Schwendeman, Anna, & Madduri, Srinivas. (2023). Natural polysaccharides and their derivatives as potential medical materials and drug delivery systems for the treatment of peripheral nerve injuries [Journal-article]. Carbohydrate Polymers, 315, 120934. https://doi.org/10.1016/j.carbpol.2023.120934

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WALZ, SOLANGE N., MARTINEAU, JÉRÔME, SCAMPA, MATTEO, MADDURI, SRINIVAS, KALBERMATTEN, DANIEL F., & ORANGES, CARLO M. (2023). Melanoma of the Lower Limbs and Hips: A Surveillance, Epidemiology, and End Results Analysis of Epidemiology and Survival 2000-2019 [Journal-article]. Anticancer Research, 43(9), 4105–4113. https://doi.org/10.21873/anticanres.16600

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Lischer M, di Summa PG, Petrou IG, Schaefer DJ, Guzman R, Kalbermatten DF, & Madduri S. (2023). Mesenchymal Stem Cells in Nerve Tissue Engineering: Bridging Nerve Gap Injuries in Large Animals. International Journal of Molecular Sciences, 24(9). https://doi.org/10.3390/ijms24097800

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Madappura, Alakananda Parassini, & Madduri, Srinivas. (2023). A comprehensive review of silk-fibroin hydrogels for cell and drug delivery applications in tissue engineering and regenerative medicine [Journal-article]. Computational and Structural Biotechnology Journal, 21, 4868–4886. https://doi.org/10.1016/j.csbj.2023.10.012

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Petrou IG, Nikou S, Madduri S, Nifora M, Bravou V, & Kalbermatten DF. (2022). The Role of Hippo Signaling Pathway and ILK in the Pathophysiology of Human Hypertrophic Scars and Keloids: An Immunohistochemical Investigation. Cells, 11(21). https://doi.org/10.3390/cells11213426

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di Summa PG, & Madduri S. (2022). Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells. Neural Regeneration Research, 17(10), 2200–2202. https://doi.org/10.4103/1673-5374.335797

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Rasineni GK, Panigrahy N, Rath SN, Chinnaboina M, Konanki R, Chirla DK, & Madduri S. (2022). Diagnostic and Therapeutic Roles of the “Omics” in Hypoxic-Ischemic Encephalopathy in Neonates. Bioengineering (Basel, Switzerland), 9(10). https://doi.org/10.3390/bioengineering9100498

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Hopf A, Al-Bayati L, Schaefer DJ, Kalbermatten DF, Guzman R, & Madduri S. (2022). Optimized Decellularization Protocol for Large Peripheral Nerve Segments: Towards Personalized Nerve Bioengineering. Bioengineering (Basel, Switzerland), 9(9). https://doi.org/10.3390/bioengineering9090412

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Migga, Alexandra, Schulz, Georg, Rodgers, Griffin, Osterwalder, Melissa, Tanner, Christine, Blank, Holger, Jerjen, Iwan, Salmon, Phil, Twengström, William, Scheel, Mario, Weitkamp, Timm, Schlepütz, Christian M., Bolten, Jan S., Huwyler, Jörg, Hotz, Gerhard, Madduri, Srinivas, & Müller, Bert. (2022). Comparative hard x-ray tomography for virtual histology of zebrafish larva, human tooth cementum, and porcine nerve. Journal of Medical Imaging, 9(3), 31507. https://doi.org/10.1117/1.jmi.9.3.031507

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Salgado A, Navarro X, & Madduri S. (2022). Editorial: Emerging Therapeutic Approaches for Repair and Regeneration of Injuries in the Peripheral Nervous System. 10, 891459. https://doi.org/10.3389/fbioe.2022.891459

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Degrugillier L, Prautsch KM, Schaefer DJ, Guzman R, Kalbermatten DF, Schären S, & Madduri S. (2021). Systematic investigation and comparison of US FDA-approved immunosuppressive drugs FK506, cyclosporine and rapamycin for neuromuscular regeneration following chronic nerve compression injury. Regenerative Medicine, 16(11), 989–1003. https://doi.org/10.2217/rme-2020-0130

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Degrugillier L, Prautsch KM, Schaefer DJ, Guzman R, Schären S, Kalbermatten DF, & Madduri S. (2021). A new model of chronic peripheral nerve compression for basic research and pharmaceutical drug testing. Regenerative Medicine, 16(10), 931–947. https://doi.org/10.2217/rme-2020-0129

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Hostettler IC, Jayashankar N, Bikis C, Wanderer S, Nevzati E, Karuppiah R, Waran V, Kalbermatten D, Mariani L, Marbacher S, Guzman R, Madduri S, & Roethlisberger M. (2021). Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery–A Systematic Review and Future Perspectives. 9, 659413. https://doi.org/10.3389/fbioe.2021.659413

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Oranges CM, Madduri S, Kalbermatten DF, & Schaefer DJ. (2021). Increasing Fat Graft Retention in Irradiated Tissue after Preconditioning with External Volume Expansion (Patent No. 1). 147(1), Article 1. https://doi.org/10.1097/PRS.0000000000007445

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Hopf A., Schaefer DJ, Kalbermatten DF, Guzman R., & Madduri S. (2020). Schwann cell-like cells: Origin and usability for repair and regeneration of the peripheral and central nervous system. Cells, 9(9), 1–31. https://doi.org/10.3390/cells9091990

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Prautsch KM, Degrugillier L, Dirk J Schaefer, Guzman R., Kalbermatten DF, & Madduri S. (2020). Ex-vivo stimulation of adipose stem cells by growth factors and fibrin-hydrogel assisted delivery strategies for treating nerve gap-injuries. Bioengineering, 7(2). https://doi.org/10.3390/bioengineering7020042

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Lischer M., Di Summa P.G., Oranges CM, Schaefer DJ, Kalbermatten DF, Guzman R., & Madduri S. (2020). Human platelet lysate stimulated adipose stem cells exhibit strong neurotrophic potency for nerve tissue engineering applications. Regenerative Medicine, 15(3), 1399–1408. https://doi.org/10.2217/rme-2020-0031

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Oranges CM, di Summa PG, Madduri S., Haug M, Kalbermatten DF, & Schaefer DJ. (2020). Fat grafting into younger recipients improves volume retention in an animal model (Patent No. 3). 145(3), Article 3. https://doi.org/10.1097/PRS.0000000000006574

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Ghosh N, Kalbermatten D, Madduri S., & Guzman R. (2020). Fibrosis and regulation of nerve regeneration in the peripheral and central nervous systems. CNS and Neurological Disorders - Drug Targets, 19(8), 560–571. https://doi.org/10.2174/1871527319666200726222558

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Prautsch, Katharina M., Schmidt, Alexander, Paradiso, Viola, Schaefer, Dirk J., Guzman, Raphael, Kalbermatten, Daniel F., & Madduri, Srinivas. (2020). Modulation of Human Adipose Stem Cells’ Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro. Cells, 9(9), 1–21. https://doi.org/10.3390/cells9091939

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Broguiere N, Husch A, Palazzolo G, Bradke F, Madduri S, & Zenobi-Wong M. (2019). Macroporous hydrogels derived from aqueous dynamic phase separation. Biomaterials, 200, 56–65. https://doi.org/10.1016/j.biomaterials.2019.01.047

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Eswaramoorthy SD, Dhiman N, Korra G, Oranges CM, Schaefer DJ, Rath SN, & Madduri S. (2019). Isogenic-induced endothelial cells enhance osteogenic differentiation of mesenchymal stem cells on silk fibroin scaffold. Regenerative Medicine, 14(7), 647–661. https://doi.org/10.2217/rme-2018-0166

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Oranges, Carlo M., Madduri, Srinivas, Brantner, Philipp, Msallem, Bilal, Giordano, Salvatore, Benitez, Benito, Kalbermatten, Daniel F., Schaefer, Dirk J., & Thieringer, Florian M. (2019). Three-dimensional Assessment of the Breast: Validation of a Novel, Simple and Inexpensive Scanning Process. In Vivo, 33(3), 839–842. https://doi.org/10.21873/invivo.11548

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Oranges CM, Striebel J, Tremp M, Madduri S, Kalbermatten DF, Harder Y, & Schaefer DJ. (2019). The preparation of the recipient site in fat grafting: A comprehensive review of the preclinical evidence. Plastic and Reconstructive Surgery, 143(4), 1099–1107. https://doi.org/10.1097/prs.0000000000005403

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Di Summa PG, Schiraldi L, Cherubino M, Oranges CM, Kalbermatten DF, Raffoul W, & Madduri S. (2018). Adipose Derived Stem Cells Reduce Fibrosis and Promote Nerve Regeneration in Rats. Anatomical record (Hoboken, N.J. : 2007), 301(10), 1714–1721. https://doi.org/10.1002/ar.23841

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Tremp M, Sprenger L., Degrugillier L., Schaefer DJ, Madduri S, Schaeren S., & Kalbermatten DF. (2018). Regeneration of nerve crush injury using adipose-derived stem cells: A multimodal comparison. Muscle and Nerve, 58(4), 566–572. https://doi.org/10.1002/mus.26188

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Wang W, Degrugillier L, Tremp M, Prautsch K, Sottaz L, Schaefer DJ, Madduri S, & Kalbermatten D. (2018). Nerve Repair With Fibrin Nerve Conduit and Modified Suture Placement. Anatomical record (Hoboken, N.J. : 2007), 301(10), 1690–1696. https://doi.org/10.1002/ar.23921

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Kappos EA, Kappos EA, Engels PE, Tremp M, Sieber PK, von Felten S, Madduri S, Meyer Zu Schwabedissen M, Fischmann A, Schaefer DJ, & Kalbermatten DF. (2018). Denervation leads to volume regression in breast cancer. Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS, 71(6), 833–839. https://doi.org/10.1016/j.bjps.2018.03.012

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Oranges CM, Tremp M, Wang W, Madduri S, DI Summa PG, Wettstein R, Schaefer DJ, & Kalbermatten DF. (2018). Patient Height, Weight, BMI and Age as Predictors of Gracilis Muscle Free-Flap Mass in Lower Extremity Reconstruction. In Vivo (Athens, Greece), 32(3), 591–595. https://doi.org/10.21873/invivo.11280

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Schiraldi L, Sottaz L, Madduri S, Campisi C, Oranges CM, Raffoul W, Kalbermatten DF, & di Summa PG. (2018). Split-sciatic nerve surgery: A new microsurgical model in experimental nerve repair. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 71(4), 557–565. https://doi.org/10.1016/j.bjps.2017.11.007

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Oranges CM, Striebel J, Tremp M, Madduri S, Kalbermatten DF, & Schaefer DJ. (2018). The Impact of Recipient Site External Expansion in Fat Grafting Surgical Outcomes. Plastic and reconstructive surgery. Global open, 6(2), e1649. https://doi.org/10.1097/gox.0000000000001649

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Bikis C., Thalmann P., Degrugillier L., Schulz G., Muller B., Kalbermatten D.F., Madduri S., & Hieber S.E. (2018). Three-dimensional and non-destructive characterization of nerves inside conduits using laboratory-based micro computed tomography. Journal of Neuroscience Methods, 294, 59–66. https://doi.org/10.1016/j.jneumeth.2017.11.005

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Bikis, Christos, Degrugillier, Lucas, Thalmann, Peter, Schulz, Georg, Müller, Bert, Hieber, Simone E., Kalbermatten, Daniel F., & Madduri, Srinivas. (2018). Three-dimensional imaging and analysis of entire peripheral nerves after repair and reconstruction. Journal of Neuroscience Methods, 295, 37–44. https://doi.org/10.1016/j.jneumeth.2017.11.015

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Oranges,Carlo, Tremp,Mathias , Madduri,Srinivas, Schaefer,Dirk Johannes, & Kalbermatten,Daniel. (2018). The Preparation of the Recipient Site in Fat Grafting: A Comprehensive Review of the Pre-Clinical Evidence. Plastic and Reconstructive Surgery .

Horst M, Milleret V, Nötzli S, Madduri S, Sulser T, Gobet R, & Eberli D. (2014). Increased porosity of electrospun hybrid scaffolds improved bladder tissue regeneration. Journal of biomedical materials research. Part A, 102(7), 2116–2124. https://doi.org/10.1002/jbm.a.34889

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Catrina S, Gander B, & Madduri S. (2013). Nerve conduit scaffolds for discrete delivery of two neurotrophic factors. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 85(1), 139–142. https://doi.org/10.1016/j.ejpb.2013.03.030

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Horst M, Madduri S, Gobet R, Sulser T, Milleret V, Hall H, Atala A, & Eberli D. (2013). Engineering functional bladder tissues. Journal of tissue engineering and regenerative medicine, 7(7), 515–522. https://doi.org/10.1002/term.547

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Horst M, Madduri S, Milleret V, Sulser T, Gobet R, & Eberli D. (2013). A bilayered hybrid microfibrous PLGA--acellular matrix scaffold for hollow organ tissue engineering. Biomaterials, 34(5), 1537–1545. https://doi.org/10.1016/j.biomaterials.2012.10.075

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Madduri S, & Gander B. (2012). Growth factor delivery systems and repair strategies for damaged peripheral nerves. Journal of controlled release : official journal of the Controlled Release Society, 161(2), 274–282. https://doi.org/10.1016/j.jconrel.2011.11.036

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Madduri S, & Gander B. (2010). Schwann cell delivery of neurotrophic factors for peripheral nerve regeneration. Journal of the peripheral nervous system : JPNS, 15(2), 93–103. https://doi.org/10.1111/j.1529-8027.2010.00257.x

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Madduri S, Feldman K, Tervoort T, Papaloïzos M, & Gander B. (2010). Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF. Journal of controlled release : official journal of the Controlled Release Society, 143(2), 168–174. https://doi.org/10.1016/j.jconrel.2009.12.017

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Madduri S, Papaloïzos M, & Gander B. (2010). Trophically and topographically functionalized silk fibroin nerve conduits for guided peripheral nerve regeneration. Biomaterials, 31(8), 2323–2334. https://doi.org/10.1016/j.biomaterials.2009.11.073

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Horst M., Madduri S., Gobet R., Sulser T., Hall H., & Eberli D. (2010). Scaffold Characteristics for functional hollow organ regeneration. Materials, 3(1), 241–263. https://doi.org/10.3390/ma3010241

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Madduri, Srinivas, di Summa, Pietro, Papaloïzos, Michaël, Kalbermatten, Daniel, & Gander, Bruno. (2010). Effect of controlled co-delivery of synergistic neurotrophic factors on early nerve regeneration in rats. Biomaterials, 31(32), 8402–8409. https://doi.org/10.1016/j.biomaterials.2010.07.052

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Madduri S, Papaloïzos M, & Gander B. (2009). Synergistic effect of GDNF and NGF on axonal branching and elongation in vitro. Neuroscience research, 65(1), 88–97. https://doi.org/10.1016/j.neures.2009.06.003

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Srinivas, Madduri, Rajakumari, Sona, Narayana, Yeddula, Joshi, Beenu, Katoch, V. M., Rajasekharan, Ram, & Balaji, Kithiganahalli N. (2008). Functional characterization of the phospholipase C activity of Rv3487c and its localization on the cell wall of Mycobacterium tuberculosis. JOURNAL OF BIOSCIENCES, 33, 221–230.

Balaji, Kithiganahalli N, Goyal, Girija, Narayana, Yeddula, Srinivas, Madduri, Chaturvedi, Rashmi, & Mohammad, Saleemulla. (2007). Apoptosis triggered by Rv1818c, a PE family gene from Mycobacterium tuberculosis is regulated by mitochondrial intermediates in T cells. Microbes and infection, 9(3), 271–281. https://doi.org/10.1016/j.micinf.2006.11.013

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Pushpalatha T, Srinivas M, & Sreenivasula Reddy P. (2005). Exposure to high fluoride concentration in drinking water will affect spermatogenesis and steroidogenesis in male albino rats. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 18(3), 207–212. https://doi.org/10.1007/s10534-005-0336-2

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