Prof. Dr. Srinivas Madduri

Mehta, Viraj, Vilikkathala Sudhakaran, Sukanya, Nellore, Vijaykumar, Madduri, Srinivas, & Rath, Subha Narayan. (2024). 3D stem-like spheroids-on-a-chip for personalized combinatorial drug testing in oral cancer [Journal-article]. Journal of Nanobiotechnology, 22(1). https://doi.org/10.1186/s12951-024-02625-y

Dogny, Clelia, André-Lévigne, Dominik, Kalbermatten, Daniel F., & Madduri, Srinivas. (2024). Therapeutic Potential and Challenges of Mesenchymal Stem Cell-Derived Exosomes for Peripheral Nerve Regeneration: A Systematic Review [Journal-article]. International Journal of Molecular Sciences, 25(12), 6489. https://doi.org/10.3390/ijms25126489

Eseme, Ebai A., Remy, Katya, Mené, Blandine L., Walz, Solange N., Madduri, Srinivas, Oranges, Carlo M., & Kalbermatten, Daniel F. (2024). Sensory and pain outcomes of neurotized skin-grafted free gracilis muscle flaps for lower extremity reconstruction [Journal-article]. Journal of Plastic, Reconstructive and Aesthetic Surgery, 92, 216–224. https://doi.org/10.1016/j.bjps.2024.02.071

André-Lévigne, Dominik, Pignel, Rodrigue, Boet, Sylvain, Jaquet, Vincent, Kalbermatten, Daniel F., & Madduri, Srinivas. (2024). Role of Oxygen and Its Radicals in Peripheral Nerve Regeneration: From Hypoxia to Physoxia to Hyperoxia [Journal-article]. International Journal of Molecular Sciences, 25(4), 2030. https://doi.org/10.3390/ijms25042030

WALZ, SOLANGE N., MARTINEAU, JEROME, SCAMPA, MATTEO, MADDURI, SRINIVAS, KALBERMATTEN, DANIEL F., & ORANGES, CARLO M. (2024). Incidence Trends of Melanoma of the Lower Limbs and Hips in the United States: A Surveillance, Epidemiology, and End Results Analysis 2000-2019 [Journal-article]. Anticancer Research, 44(1), 239–247. https://doi.org/10.21873/anticanres.16807

Fenelon, Mathilde, Galvez, Paul, Kalbermatten, Daniel, Scolozzi, Paolo, & Madduri, Srinivas. (2023). Emerging Strategies for the Biofabrication of Multilayer Composite Amniotic Membranes for Biomedical Applications [Journal-article]. International Journal of Molecular Sciences, 24(19), 14424. https://doi.org/10.3390/ijms241914424

Solomevich, Sergey O., Oranges, Carlo M., Kalbermatten, Daniel F., Schwendeman, Anna, & Madduri, Srinivas. (2023). Natural polysaccharides and their derivatives as potential medical materials and drug delivery systems for the treatment of peripheral nerve injuries [Journal-article]. Carbohydrate Polymers, 315, 120934. https://doi.org/10.1016/j.carbpol.2023.120934

WALZ, SOLANGE N., MARTINEAU, JÉRÔME, SCAMPA, MATTEO, MADDURI, SRINIVAS, KALBERMATTEN, DANIEL F., & ORANGES, CARLO M. (2023). Melanoma of the Lower Limbs and Hips: A Surveillance, Epidemiology, and End Results Analysis of Epidemiology and Survival 2000-2019 [Journal-article]. Anticancer Research, 43(9), 4105–4113. https://doi.org/10.21873/anticanres.16600

Lischer, Mirko, di Summa, Pietro G., Petrou, Ilias G., Schaefer, Dirk J., Guzman, Raphael, Kalbermatten, Daniel F., & Madduri, Srinivas. (2023). Mesenchymal Stem Cells in Nerve Tissue Engineering: Bridging Nerve Gap Injuries in Large Animals. International Journal of Molecular Sciences, 24(9). https://doi.org/10.3390/ijms24097800

Madappura, Alakananda Parassini, & Madduri, Srinivas. (2023). A comprehensive review of silk-fibroin hydrogels for cell and drug delivery applications in tissue engineering and regenerative medicine [Journal-article]. Computational and Structural Biotechnology Journal, 21, 4868–4886. https://doi.org/10.1016/j.csbj.2023.10.012

Petrou IG, Nikou S, Madduri S, Nifora M, Bravou V, & Kalbermatten DF. (2022). The Role of Hippo Signaling Pathway and ILK in the Pathophysiology of Human Hypertrophic Scars and Keloids: An Immunohistochemical Investigation. Cells, 11(21). https://doi.org/10.3390/cells11213426

di Summa PG, & Madduri S. (2022). Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells. Neural Regeneration Research, 17(10), 2200–2202. https://doi.org/10.4103/1673-5374.335797

Rasineni GK, Panigrahy N, Rath SN, Chinnaboina M, Konanki R, Chirla DK, & Madduri S. (2022). Diagnostic and Therapeutic Roles of the “Omics” in Hypoxic–Ischemic Encephalopathy in Neonates. Bioengineering, 9(10). https://doi.org/10.3390/bioengineering9100498

Hopf A, Al-Bayati L, Schaefer DJ, Kalbermatten DF, Guzman R, & Madduri S. (2022). Optimized Decellularization Protocol for Large Peripheral Nerve Segments: Towards Personalized Nerve Bioengineering. Bioengineering, 9(9). https://doi.org/10.3390/bioengineering9090412

Salgado A, Navarro X, & Madduri S. (2022). Editorial: Emerging Therapeutic Approaches for Repair and Regeneration of Injuries in the Peripheral Nervous System [Frontiers Media S.A.]. Frontiers in Bioengineering and Biotechnology, 10, 891459. https://doi.org/10.3389/fbioe.2022.891459

Migga, Alexandra, Schulz, Georg, Rodgers, Griffin, Osterwalder, Melissa, Tanner, Christine, Blank, Holger, Jerjen, Iwan, Salmon, Phil, Twengström, William, Scheel, Mario, Weitkamp, Timm, Schlepütz, Christian M., Bolten, Jan S., Huwyler, Jörg, Hotz, Gerhard, Madduri, Srinivas, & Müller, Bert. (2022). Comparative hard x-ray tomography for virtual histology of zebrafish larva, human tooth cementum, and porcine nerve. Journal of Medical Imaging, 9(3), 31507. https://doi.org/10.1117/1.jmi.9.3.031507

Degrugillier L, Prautsch KM, Schaefer DJ, Guzman R, Kalbermatten DF, Schären S, & Madduri S. (2021). Systematic investigation and comparison of US FDA-approved immunosuppressive drugs FK506, cyclosporine and rapamycin for neuromuscular regeneration following chronic nerve compression injury. Regenerative Medicine, 16(11), 989–1003. https://doi.org/10.2217/rme-2020-0130

Degrugillier L, Prautsch KM, Schaefer DJ, Guzman R, Schären S, Kalbermatten DF, & Madduri S. (2021). A new model of chronic peripheral nerve compression for basic research and pharmaceutical drug testing. Regenerative Medicine, 16(10), 931–947. https://doi.org/10.2217/rme-2020-0129

Hostettler IC, Jayashankar N, Bikis C, Wanderer S, Nevzati E, Karuppiah R, Waran V, Kalbermatten D, Mariani L, Marbacher S, Guzman R, Madduri S, & Roethlisberger M. (2021). Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery–A Systematic Review and Future Perspectives [Frontiers Media S.A.]. Frontiers in Bioengineering and Biotechnology, 9, 659413. https://doi.org/10.3389/fbioe.2021.659413

Oranges CM, Madduri S, Kalbermatten DF, & Schaefer DJ. (2021). Increasing Fat Graft Retention in Irradiated Tissue after Preconditioning with External Volume Expansion (Patent No. 1). Plastic and Reconstructive Surgery, 147(1), Article 1. https://doi.org/10.1097/prs.0000000000007445

Hopf A., Schaefer DJ, Kalbermatten DF, Guzman R., & Madduri S. (2020). Schwann cell-like cells: Origin and usability for repair and regeneration of the peripheral and central nervous system. Cells, 9(9), 1–31. https://doi.org/10.3390/cells9091990

Prautsch KM, Degrugillier L, Dirk J Schaefer, Guzman R., Kalbermatten DF, & Madduri S. (2020). Ex-vivo stimulation of adipose stem cells by growth factors and fibrin-hydrogel assisted delivery strategies for treating nerve gap-injuries. Bioengineering, 7(2). https://doi.org/10.3390/bioengineering7020042

Lischer M., Di Summa P.G., Oranges CM, Schaefer DJ, Kalbermatten DF, Guzman R., & Madduri S. (2020). Human platelet lysate stimulated adipose stem cells exhibit strong neurotrophic potency for nerve tissue engineering applications. Regenerative Medicine, 15(3), 1399–1408. https://doi.org/10.2217/rme-2020-0031

Oranges CM, di Summa PG, Madduri S., Haug M, Kalbermatten DF, & Schaefer DJ. (2020). Fat grafting into younger recipients improves volume retention in an animal model (Patent No. 3). Plastic and Reconstructive Surgery, 145(3), Article 3. https://doi.org/10.1097/prs.0000000000006574

Ghosh N, Kalbermatten D, Madduri S., & Guzman R. (2020). Fibrosis and regulation of nerve regeneration in the peripheral and central nervous systems. CNS and Neurological Disorders - Drug Targets, 19(8), 560–571. https://doi.org/10.2174/1871527319666200726222558

Prautsch, Katharina M., Schmidt, Alexander, Paradiso, Viola, Schaefer, Dirk J., Guzman, Raphael, Kalbermatten, Daniel F., & Madduri, Srinivas. (2020). Modulation of Human Adipose Stem Cells’ Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro. Cells, 9(9), 1–21. https://doi.org/10.3390/cells9091939

Broguiere N, Husch A, Palazzolo G, Bradke F, Madduri S, & Zenobi-Wong M. (2019). Macroporous hydrogels derived from aqueous dynamic phase separation. Biomaterials, 200, 56–65. https://doi.org/10.1016/j.biomaterials.2019.01.047

Eswaramoorthy SD, Dhiman N, Korra G, Oranges CM, Schaefer DJ, Rath SN, & Madduri S. (2019). Isogenic-induced endothelial cells enhance osteogenic differentiation of mesenchymal stem cells on silk fibroin scaffold. Regenerative Medicine, 14(7), 647–661. https://doi.org/10.2217/rme-2018-0166

Oranges, Carlo M., Madduri, Srinivas, Brantner, Philipp, Msallem, Bilal, Giordano, Salvatore, Benitez, Benito, Kalbermatten, Daniel F., Schaefer, Dirk J., & Thieringer, Florian M. (2019). Three-dimensional Assessment of the Breast: Validation of a Novel, Simple and Inexpensive Scanning Process. In Vivo, 33(3), 839–842. https://doi.org/10.21873/invivo.11548

Oranges CM, Striebel J, Tremp M, Madduri S, Kalbermatten DF, Harder Y, & Schaefer DJ. (2019). The preparation of the recipient site in fat grafting: A comprehensive review of the preclinical evidence. Plastic and Reconstructive Surgery, 143(4), 1099–1107. https://doi.org/10.1097/PRS.0000000000005403

Oranges,Carlo, Tremp,Mathias , Madduri,Srinivas, Schaefer,Dirk Johannes, & Kalbermatten,Daniel. (2018). The Preparation of the Recipient Site in Fat Grafting: A Comprehensive Review of the Pre-Clinical Evidence. Plastic and Reconstructive Surgery .

Di Summa PG, Schiraldi L, Cherubino M, Oranges CM, Kalbermatten DF, Raffoul W, & Madduri S. (2018). Adipose Derived Stem Cells Reduce Fibrosis and Promote Nerve Regeneration in Rats. Anatomical Record, 301(10), 1714–1721. https://doi.org/10.1002/ar.23841

Tremp M, Sprenger L., Degrugillier L., Schaefer DJ, Madduri S, Schaeren S., & Kalbermatten DF. (2018). Regeneration of nerve crush injury using adipose-derived stem cells: A multimodal comparison. Muscle and Nerve, 58(4), 566–572. https://doi.org/10.1002/mus.26188

Wang W, Degrugillier L, Tremp M, Prautsch K, Sottaz L, Schaefer DJ, Madduri S, & Kalbermatten D. (2018). Nerve Repair With Fibrin Nerve Conduit and Modified Suture Placement. Anatomical Record, 301(10), 1690–1696. https://doi.org/10.1002/ar.23921

Kappos EA, Kappos EA, Engels PE, Tremp M, Sieber PK, von Felten S, Madduri S, Meyer Zu Schwabedissen M, Fischmann A, Schaefer DJ, & Kalbermatten DF. (2018). Denervation leads to volume regression in breast cancer. Journal of Plastic, Reconstructive and Aesthetic Surgery, 71(6), 833–839. https://doi.org/10.1016/j.bjps.2018.03.012

Oranges CM, Tremp M, Wang W, Madduri S, DI Summa PG, Wettstein R, Schaefer DJ, & Kalbermatten DF. (2018). Patient height, weight, BMI and age as predictors of gracilis muscle free-flap mass in lower extremity reconstruction. In Vivo, 32(3), 591–595. https://doi.org/10.21873/invivo.11280

Schiraldi L, Sottaz L, Madduri S, Campisi C, Oranges CM, Raffoul W, Kalbermatten DF, & di Summa PG. (2018). Split-sciatic nerve surgery: A new microsurgical model in experimental nerve repair. Journal of Plastic, Reconstructive and Aesthetic Surgery, 71(4), 557–565. https://doi.org/10.1016/j.bjps.2017.11.007

Bikis, Christos, Degrugillier, Lucas, Thalmann, Peter, Schulz, Georg, Müller, Bert, Hieber, Simone E., Kalbermatten, Daniel F., & Madduri, Srinivas. (2018). Three-dimensional imaging and analysis of entire peripheral nerves after repair and reconstruction. Journal of Neuroscience Methods, 295, 37–44. https://doi.org/10.1016/j.jneumeth.2017.11.015

Bikis C., Thalmann P., Degrugillier L., Schulz G., Muller B., Kalbermatten D.F., Madduri S., & Hieber S.E. (2018). Three-dimensional and non-destructive characterization of nerves inside conduits using laboratory-based micro computed tomography. Journal of Neuroscience Methods, 294, 59–66. https://doi.org/10.1016/j.jneumeth.2017.11.005

Oranges CM, Striebel J, Tremp M, Madduri S, Kalbermatten DF, & Schaefer DJ. (2018). The impact of recipient site external expansion in fat grafting surgical outcomes. Plastic and Reconstructive Surgery - Global Open, 6(2), 1–8. https://doi.org/10.1097/GOX.0000000000001649

Horst M, Milleret V, Nötzli S, Madduri S, Sulser T, Gobet R, & Eberli D. (2014). Increased porosity of electrospun hybrid scaffolds improved bladder tissue regeneration. Journal of Biomedical Materials Research - Part A, 102(7), 2116–2124. https://doi.org/10.1002/jbm.a.34889

Catrina S, Gander B, & Madduri S. (2013). Nerve conduit scaffolds for discrete delivery of two neurotrophic factors. European Journal of Pharmaceutics and Biopharmaceutics, 85(1), 139–142. https://doi.org/10.1016/j.ejpb.2013.03.030

Horst M, Madduri S, Milleret V, Sulser T, Gobet R, & Eberli D. (2013). A bilayered hybrid microfibrous PLGA-Acellular matrix scaffold for hollow organ tissue engineering. Biomaterials, 34(5), 1537–1545. https://doi.org/10.1016/j.biomaterials.2012.10.075

Horst M, Madduri S, Gobet R, Sulser T, Milleret V, Hall H, Atala A, & Eberli D. (2013). Engineering functional bladder tissues. Journal of Tissue Engineering and Regenerative Medicine, 7(7), 515–522. https://doi.org/10.1002/term.547

Madduri S, & Gander B. (2012). Growth factor delivery systems and repair strategies for damaged peripheral nerves. Journal of Controlled Release, 161(2), 274–282. https://doi.org/10.1016/j.jconrel.2011.11.036

Horst M., Madduri S., Gobet R., Sulser T., Hall H., & Eberli D. (2010). Scaffold Characteristics for functional hollow organ regeneration. Materials, 3(1), 241–263. https://doi.org/10.3390/ma3010241

Madduri S, & Gander B. (2010). Schwann cell delivery of neurotrophic factors for peripheral nerve regeneration. Journal of the Peripheral Nervous System, 15(2), 93–103. https://doi.org/10.1111/j.1529-8027.2010.00257.x

Madduri S, Feldman K, Tervoort T, Papaloïzos M, & Gander B. (2010). Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF. Journal of Controlled Release, 143(2), 168–174. https://doi.org/10.1016/j.jconrel.2009.12.017

Madduri S, Papaloïzos M, & Gander B. (2010). Trophically and topographically functionalized silk fibroin nerve conduits for guided peripheral nerve regeneration. Biomaterials, 31(8), 2323–2334. https://doi.org/10.1016/j.biomaterials.2009.11.073

Madduri, Srinivas, di Summa, Pietro, Papaloïzos, Michaël, Kalbermatten, Daniel, & Gander, Bruno. (2010). Effect of controlled co-delivery of synergistic neurotrophic factors on early nerve regeneration in rats. Biomaterials, 31(32), 9–8402. https://doi.org/10.1016/j.biomaterials.2010.07.052

Madduri S, Papaloïzos M, & Gander B. (2009). Synergistic effect of GDNF and NGF on axonal branching and elongation in vitro. Neuroscience Research, 65(1), 88–97. https://doi.org/10.1016/j.neures.2009.06.003

Srinivas, Madduri, Rajakumari, Sona, Narayana, Yeddula, Joshi, Beenu, Katoch, V. M., Rajasekharan, Ram, & Balaji, Kithiganahalli N. (2008). Functional characterization of the phospholipase C activity of Rv3487c and its localization on the cell wall of Mycobacterium tuberculosis. JOURNAL OF BIOSCIENCES, 33, 221–230. https://doi.org/10.1007/s12038-008-0039-2

Balaji, Kithiganahalli N, Goyal, Girija, Narayana, Yeddula, Srinivas, Madduri, Chaturvedi, Rashmi, & Mohammad, Saleemulla. (2007). Apoptosis triggered by Rv1818c, a PE family gene from Mycobacterium tuberculosis is regulated by mitochondrial intermediates in T cells. Microbes and Infection, 9(3), 271–281. https://doi.org/10.1016/j.micinf.2006.11.013

Pushpalatha T, Srinivas M, & Sreenivasula Reddy P. (2005). Exposure to high fluoride concentration in drinking water will affect spermatogenesis and steroidogenesis in male albino rats. BioMetals, 18(3), 207–212. https://doi.org/10.1007/s10534-005-0336-2