Dr. Tolga Daniel Dittrich

Kliem, Paulina S. C., Tisljar, Kai, Grzonka, Pascale, Berger, Sebastian, Amacher, Simon A., De Marchis, Gian Marco, Dittrich, Tolga D., Hunziker, Sabina, Rüegg, Stephan, Bassetti, Stefano, Bingisser, Roland, Marsch, Stephan, & Sutter, Raoul. (2025). Effects of a scoring aid on glasgow coma score assessment and physicians’ comprehension: a simulator-based randomized clinical trial. Journal of Neurology, 272. https://doi.org/10.1007/s00415-024-12825-z

Dittrich, Tolga D., Schneider, Thomas, Katan, Mira, Luft, Andreas R., Mono, Marie-Luise, Bolognese, Manuel, Nedeltchev, Krassen, Kahles, Timo, Arnold, Marcel, Heldner, Mirjam, Michel, Patrik, Carrera, Emmanuel, Rodic, Biljana, Cereda, Carlo W., Peters, Nils, Bonati, Leo H., Renaud, Susanne, Humm, Andrea M., Medlin, Friedrich, et al. (2024). Risk Factors, Treatments, and Outcomes of Adults Aged <55 Years With Acute Ischemic Stroke With Undetermined Versus Determined Pathogenesis: A Nationwide Swiss Cohort Study. Journal of the American Heart Association, 13. https://doi.org/10.1161/JAHA.124.036761

Dittrich, Tolga D., Vock, Dominik, Fisch, Urs, Hert, Lisa, Baumann, Sira M., Kliem, Paulina S.C., Rüegg, Stephan, Marsch, Stephan, De Marchis, Gian Marco, & Sutter, Raoul. (2024). Efficacy and Tolerability of Intranasal Midazolam Administration for Antiseizure Treatment in Adults: A Systematic Review. Neurocritical Care, 41(2), 632–650. https://doi.org/10.1007/s12028-024-01971-x

Dittrich, Tolga D, von Streng, Tennessee, Toebak, Anna M, Zietz, Annaelle, Wagner, Benjamin, Hänsel, Martin, Sutter, Raoul, Katan, Mira, Peters, Nils, Michels, Lars, Kulcsár, Zsolt, Karwacki, Grzegorz M, Pileggi, Marco, Cereda, Carlo W, Wegener, Susanne, Bonati, Leo H, Psychogios, Marios, & De Marchis, Gian Marco. (2024). Absent leptomeningeal collateralization is associated with greatest benefit from mechanical thrombectomy in the 6-24 hour time window. European Stroke Journal, 9, 592–599. https://doi.org/10.1177/23969873241239208

Kriemler, Lilian, Rudin, Salome, Gawinecka, Joanna, Gross, Felix, Arnold, Markus, Schweizer, Juliane, Westphal, Laura, Inauen, Corinne, Pokorny, Thomas, Dittrich, Tolga, Toebak, Anna, Arnold, Marcel, Christ-Crain, Mirjam, von Eckardstein, Arnold, Rentsch, Katharina, Katan, Mira, & De Marchis, Gian Marco. (2024). Discordance between LDL-C and apolipoprotein B is associated with large-artery-atherosclerosis ischemic stroke in patients ⩽70 years of age. European Stroke Journal, 9(2), 494–500. https://doi.org/10.1177/23969873231221619

Marvardi, M., Ferrante, M., Paciaroni, M., Abdul-Rahim, A., Tsivgoulis, G., Seiffge, D. J., Engelter, S. T., Lyrer, P., Polymeris, A. A., Dittrich, T., Cancelloni, V., Zietz, A., De Marchis, G. M., Putaala, J., Strbian, D., Tomppo, L., Michel, P., Strambo, D., Salerno, A., et al. (2024). Statin Therapy in Ischemic Stroke Patients with Atrial Fibrillation: Efficacy and Safety Outcomes [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.04.19.24306111

Dittrich, Tolga D, Nguyen, Anh, Sporns, Peter B, Toebak, Anna M, Kriemler, Lilian F, Rudin, Salome, Zietz, Annaelle, Wagner, Benjamin, Barinka, Filip, Hänsel, Martin, Gensicke, Henrik, Sutter, Raoul, Nickel, Christian H, Katan, Mira, Peters, Nils, Michels, Lars, Kulcsár, Zsolt, Karwacki, Grzegorz M, Pileggi, Marco, et al. (2024). Large ischemic core defined by visually assessed ASPECTS predicts functional outcomes comparably accurate to automated CT perfusion in the 6–24 h window. European Stroke Journal. https://doi.org/10.1177/23969873241286691

Rudin, Salome, Kriemler, Lilian, Dittrich, Tolga D., Zietz, Annaelle, Schweizer, Juliane, Arnold, Markus, Peters, Nils, Barinka, Filip, Jung, Simon, Arnold, Marcel, Fischer, Urs, Rentsch, Katharina, Christ-Crain, Mirjam, Katan, Mira, & De Marchis, Gian Marco. (2024). Lipoprotein(a) as a blood marker for large artery atherosclerosis stroke etiology: validation in a prospective cohort from a swiss stroke center. Swiss Medical Weekly, 154. https://doi.org/10.57187/s.3633

Sojak, Lina, Toebak, Anna M., Gallino, Camilla, von Streng, Tennessee, Rudin, Salome, Kriemler, Lilian F., Zietz, Annaelle, Wagner, Benjamin, Gensicke, Henrik, Sutter, Raoul, Nickel, Christian H., Katan, Mira, Bonati, Leo H., Psychogios, Marios, Dittrich, Tolga D., & De Marchis, Gian Marco. (2024). Association between ischaemic stroke aetiology and leptomeningeal collateral status: a retrospective cohort study. Swiss Medical Weekly, 154. https://doi.org/10.57187/s.3584

Baumann, Sira M., Kruse, Natalie J., Kliem, Paulina S. C., Amacher, Simon A., Hunziker, Sabina, Dittrich, Tolga D., Renetseder, Fabienne, Grzonka, Pascale, & Sutter, Raoul. (2023). Translation of patients’ advance directives in intensive care units: are we there yet? Journal of Intensive Care, 11(1). https://doi.org/10.1186/s40560-023-00705-z

Bakradze, Ekaterina, Shu, Liqi, Henninger, Nils, Prabhakaran, Shyam, Siegler, James E., De Marchis, Gian Marco, Giles, James A., Dittrich, Tolga, Heldner, Mirjam R., Antonenko, Kateryna, Kam, Wayneho, Liebeskind, David S., Simpkins, Alexis N., Nguyen, Thanh N., Yaghi, Shadi, & Liberman, Ava L. (2023). Delayed Diagnosis in Cerebral Venous Thrombosis: Associated Factors and Clinical Outcomes. Journal of the American Heart Association, 12(19). https://doi.org/10.1161/JAHA.123.030421

De Marchis, Gian Marco, Krisai, Philipp, Werlen, Laura, Sinnecker, Tim, Aeschbacher, Stefanie, Dittrich, Tolga D., Polymeris, Alexandros A., Coslovksy, Michael, Blum, Manuel R., Rodondi, Nicolas, Reichlin, Tobias, Moschovitis, Giorgio, Wuerfel, Jens, Lyrer, Philippe A., Fischer, Urs, Conen, David, Kastner, Peter, Ziegler, André, Osswald, Stefan, et al. (2023). Biomarker, Imaging, and Clinical Factors Associated with Overt and Covert Stroke in Patients with Atrial Fibrillation. Stroke, 54, 2542–2551. https://doi.org/10.1161/STROKEAHA.123.043302

Kubacka, Marta, Zietz, Annaelle, Schaedelin, Sabine, Polymeris, Alexandros A., Hert, Lisa, Lieb, Johanna, Wagner, Benjamin, Seiffge, David, Traenka, Christopher, Altersberger, Valerian L., Dittrich, Tolga, Fladt, Joachim, Fisch, Urs, Thilemann, Sebastian, De Marchis, Gian Marco, Gensicke, Henrik, Bonati, Leo H., Lyrer, Philippe, Engelter, Stefan T., & Peters, Nils. (2023). Global Cortical Atrophy Is Associated with an Unfavorable Outcome in Stroke Patients on Oral Anticoagulation. Cerebrovascular Diseases, 52(5), 495–502. https://doi.org/10.1159/000527739

Caliandro, P., Cancelloni, V., Marco, M., Reale, G., Zauli, A., Agnelli, G., Caso, V., Becattini, C., Calabresi, P., Giulia Mosconi, M., Giustozzi, M., Tsivgoulis, G., Julian Seiffge, D., Engelter, S. T., Lyrer, P., Polymeris, A. A., Dittrich, T., Zietz, A., Marco De Marchis, G., et al. (2023). Risk of recurrent stroke in patients with atrial fibrillation treated with oral anticoagulants alone or in combination with anti-platelet therapy. European Stroke Journal, 8(3), 722–730. https://doi.org/10.1177/23969873231183211

Polymeris, Alexandros A., Karwacki, Grzegorz M., Siepen, Bernhard M., Schaedelin, Sabine, Tsakiris, Dimitrios A., Stippich, Christoph, Guzman, Raphael, Nickel, Christian H., Sprigg, Nikola, Kägi, Georg, Vehoff, Jochen, Barinka, Filip, Thilemann, Sebastian, Maurer, Marina, Wagner, Benjamin, Traenka, Christopher, Gensicke, Henrik, De Marchis, Gian Marco, Bonati, Leo H., et al. (2023). Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial. Stroke, 54, 2223–2234. https://doi.org/10.1161/STROKEAHA.123.042866

Zietz, Annaelle, Polymeris, Alexandros A, Helfenstein, Fabrice, Schaedelin, Sabine, Hert, Lisa, Wagner, Benjamin, Seiffge, David J, Traenka, Christopher, Altersberger, Valerian L, Dittrich, Tolga, Kaufmann, Josefin, Ravanelli, Flavia, Fladt, Joachim, Fisch, Urs, Thilemann, Sebastian, De Marchis, Gian Marco, Gensicke, Henrik, Bonati, Leo H, Katan, Mira, et al. (2023). The impact of competing stroke etiologies in patients with atrial fibrillation. European Stroke Journal, 8, 703–711. https://doi.org/10.1177/23969873231185220

Dittrich, Tolga D, Sporns, Peter B, Kriemler, Lilian F, Rudin, Salome, Nguyen, Anh, Zietz, Annaelle, Polymeris, Alexandros A, Tränka, Christopher, Thilemann, Sebastian, Wagner, Benjamin, Altersberger, Valerian L, Piot, Ines, Barinka, Filip, Hänsel, Martin, Gensicke, Henrik, Engelter, Stefan T, Lyrer, Philippe A, Sutter, Raoul, Nickel, Christian H, et al. (2023). Mechanical thrombectomy for large vessel occlusion between 6 and 24 h: outcome comparison of DEFUSE-3/DAWN eligible versus non-eligible patients. International Journal of Stroke, 18, 697–703. https://doi.org/10.1177/17474930221140793

Lyrer, Flurina, Zietz, Annaelle, Seiffge, David J., Koga, Masatoshi, Volbers, Bastian, Wilson, Duncan, Bonetti, Bruno, Schaedelin, Sabine, Gensicke, Henrik, Yoshimura, Sohei, Macha, Kosmas, Ambler, Gareth, Thilemann, Sebastian, Dittrich, Tolga, Inoue, Manabu, Miwa, Kaori, Wang, Ruihao, Siedler, Gabriela, Biburger, Luise, et al. (2023). Atrial Fibrillation Detected before or after Stroke: Role of Anticoagulation. Annals of Neurology, 94, 43–54. https://doi.org/10.1002/ana.26654

Dittrich, Tolga D, Aujesky, Mara, Rudin, Salome, Zietz, Annaelle, Wagner, Benjamin, Polymeris, Alexandros, Altersberger, Valerian L, Sinnecker, Tim, Gensicke, Henrik, Engelter, Stefan T, Lyrer, Philippe, Hess, Viviane, Sutter, Raoul, Nickel, Christian H, Bonati, Leo H, Fischer, Urs, Psychogios, Marios, Katan, Mira, & De Marchis, Gian Marco. (2023). Apical pulmonary lesions suspected of malignancy visible on neck CT angiography performed for acute stroke: Prevalence, treatment, and clinical implications – the PLEURA study. European Stroke Journal, 8(2), 549–556. https://doi.org/10.1177/23969873231151488

Dittrich, Tolga D., Sporns, Peter B., Kriemler, Lilian F., Rudin, Salome, Nguyen, Anh, Zietz, Annaelle, Polymeris, Alexandros A., Tränka, Christopher, Thilemann, Sebastian, Wagner, Benjamin, Altersberger, Valerian L., Piot, Ines, Barinka, Filip, Müller, Susanne, Hänsel, Martin, Gensicke, Henrik, Engelter, Stefan T., Lyrer, Philippe A., Sutter, Raoul, et al. (2023). Mechanical Thrombectomy Versus Best Medical Treatment in the Late Time Window in Non-DEFUSE-Non-DAWN Patients: A Multicenter Cohort Study. Stroke, 54(3), 722–730. https://doi.org/10.1161/STROKEAHA.122.039793

Roaldsen, Melinda B, Eltoft, Agnethe, Wilsgaard, Tom, Christensen, Hanne, Engelter, Stefan T, Indredavik, Bent, Jatužis, Dalius, Karelis, Guntis, Kõrv, Janika, Lundström, Erik, Petersson, Jesper, Putaala, Jukka, Søyland, Mary-Helen, Tveiten, Arnstein, Bivard, Andrew, Johnsen, Stein Harald, Mazya, Michael V, Werring, David J, Wu, Teddy Y, et al. (2023). Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial. The Lancet Neurology, 22(2), 117–126. https://doi.org/10.1016/S1474-4422(22)00484-7

Shu L, Bakradze E, Omran SS, Giles J, Amar J, Henninger N, Elnazeir M, Liberman A, Moncrieffe K, Rotblat J, Sharma R, Cheng Y, Zubair AS, Simpkins A, Li G, Kung J, Perez D, Heldner MR, Scutelnic A, et al. (2022). Predictors of Recurrent Venous Thrombosis after Cerebral Venous Thrombosis: Analysis of the ACTION-CVT Study. Neurology, 99(21), E2368–E2377. https://doi.org/10.1212/WNL.0000000000201122

De Marchis GM, Dittrich TD, Malik R, Zietz AV, Kriemler LF, Ference BA, Dichgans M, & Georgakis MK. (2022). Genetic proxies for PCSK9 inhibition associate with lipoprotein(a): Effects on coronary artery disease and ischemic stroke. Atherosclerosis, 361, 41–46. https://doi.org/10.1016/j.atherosclerosis.2022.09.007

Wagner, Benjamin, Hert, Lisa, Polymeris, Alexandros A., Schaedelin, Sabine, Lieb, Johanna M., Seiffge, David J., Traenka, Christopher, Thilemann, Sebastian, Fladt, Joachim, Altersberger, Valerian L., Zietz, Annaelle, Dittrich, Tolga D., Fisch, Urs, Gensicke, Henrik, De Marchis, Gian Marco, Bonati, Leo H., Lyrer, Philippe A., Engelter, Stefan T., & Peters, Nils. (2022). Impact of type of oral anticoagulants in patients with cerebral microbleeds after atrial fibrillation-related ischemic stroke or TIA: Results of the NOACISP-LONGTERM registry. Frontiers in Neurology, 13. https://doi.org/10.3389/fneur.2022.964723

Polymeris, Alexandros A, Zietz, Annaelle, Schaub, Fabian, Meya, Louisa, Traenka, Christopher, Thilemann, Sebastian, Wagner, Benjamin, Hert, Lisa, Altersberger, Valerian L, Seiffge, David J, Lyrer, Flurina, Dittrich, Tolga, Piot, Ines, Kaufmann, Josefin, Barone, Lea, Dahlheim, Ludvig, Flammer, Sophie, Avramiotis, Nikolaos S, Peters, Nils, et al. (2022). Once versus twice daily direct oral anticoagulants in patients with recent stroke and atrial fibrillation. European Stroke Journal, 7(3), 221–229. https://doi.org/10.1177/23969873221099477

Yaghi S, Shu L, Bakradze E, Salehi Omran S, Giles JA, Amar JY, Henninger N, Elnazeir M, Liberman AL, Moncrieffe K, Lu J, Sharma R, Cheng Y, Zubair AS, Simpkins AN, Li GT, Kung JC, Perez D, Heldner M, et al. (2022). Direct Oral Anticoagulants Versus Warfarin in the Treatment of Cerebral Venous Thrombosis (ACTION-CVT): A Multicenter International Study. Stroke, 29(2), 728–738. https://doi.org/10.1161/STROKEAHA.121.037541

Potasso L, Refardt J, De Marchis GM, Wiencierz A, Wright PR, Wagner B, Dittrich T, Polymeris AA, Gensicke H, Bonati LH, & Christ-Crain M. (2022). Impact of Sodium Levels on Functional Outcomes in Patients with Stroke - A Swiss Stroke Registry Analysis. Journal of Clinical Endocrinology and Metabolism, 107(2), E672–E680. https://doi.org/10.1210/clinem/dgab650

Chun HY, Dittrich T, Øygarden H, & Li L. (2022). European Stroke Organisation Conference 2021 Plenary Highlights. Stroke, 53(1), E21–E22. https://doi.org/10.1161/STROKEAHA.121.037634

Polymeris, Alexandros A, Macha, Kosmas, Paciaroni, Maurizio, Wilson, Duncan, Koga, Masatoshi, Cappellari, Manuel, Schaedelin, Sabine, Zietz, Annaelle, Peters, Nils, Seiffge, David J, Haupenthal, David, Gassmann, Luise, De Marchis, Gian Marco, Wang, Ruihao, Gensicke, Henrik, Stoll, Svenja, Thilemann, Sebastian, Avramiotis, Nikolaos S, Bonetti, Bruno, et al. (2022). Oral Anticoagulants in the Oldest Old with Recent Stroke and Atrial Fibrillation. Annals of Neurology, 91(1), 78–88. https://doi.org/10.1002/ana.26267

Meya, Louisa, Polymeris, Alexandros A., Schaedelin, Sabine, Schaub, Fabian, Altersberger, Valerian L., Traenka, Christopher, Thilemann, Sebastian, Wagner, Benjamin, Fladt, Joachim, Hert, Lisa, Yoshimura, Sohei, Koga, Masatoshi, Zietz, Annaelle, Dittrich, Tolga, Fisch, Urs, Toyoda, Kazunori, Seiffge, David J., Peters, Nils, De Marchis, Gian Marco, et al. (2021). Oral Anticoagulants in Atrial Fibrillation Patients with Recent Stroke Who Are Dependent on the Daily Help of Others. Stroke, 52(11), 3472–3481. https://doi.org/10.1161/STROKEAHA.120.033862

De Marchis, Gian Marco, & Dittrich, Tolga D. (2021). Blood biomarkers in the diagnosis of acute stroke (pp. 163–189). Springer International Publishing. https://doi.org/10.1007/978-3-030-70761-3_8

De Marchis GM, Sposato L.A., Kuhne M., Dittrich TD, Bonati LH, Fischer U, & Chaturvedi S. (2021). New Avenues for Optimal Treatment of Atrial Fibrillation and Stroke Prevention. Stroke, 52(4), 1490–1499. https://doi.org/10.1161/STROKEAHA.120.032060

Dittrich, Tolga D., Baumann, Sira M., Semmlack, Saskia, De Marchis, Gian Marco, Hunziker, Sabina, Rüegg, Stephan, Marsch, Stephan, Tschudin-Sutter, Sarah, & Sutter, Raoul. (2021). Diagnostic yield of cerebrospinal fluid analysis in status epilepticus: an 8-year cohort study. Journal of Neurology, 268(9), 3325–3336. https://doi.org/10.1007/s00415-021-10447-3

Dittrich, Tolga, Marsch, Stephan, Rüegg, Stephan, De Marchis, Gian Marco, Tschudin-Sutter, Sarah, & Sutter, Raoul. (2021). Delirium in Meningitis and Encephalitis: Emergence and Prediction in a 6-Year Cohort. Journal of Intensive Care Medicine, 36(5), 566–575. https://doi.org/10.1177/0885066620913004

Dittrich, Tolga, Polymeris, Alexandros, & De Marchis, Gian Marco. (2021). Challenges of treatment adherence with direct oral anticoagulants in pandemic. Current Opinion in Neurology, 34(1), 38–44. https://doi.org/10.1097/wco.0000000000000888

Dittrich, Tolga, Marsch, Stephan, Egli, Adrian, Rüegg, Stephan, De Marchis, Gian Marco, Tschudin-Sutter, Sarah, & Sutter, Raoul. (2020). Predictors of infectious meningitis or encephalitis: the yield of cerebrospinal fluid in a cross-sectional study. BMC Infectious Diseases, 20(1), 304. https://doi.org/10.1186/s12879-020-05022-6

Sutter, Raoul, Dittrich, Tolga, Semmlack, Saskia, Rüegg, Stephan, Marsch, Stephan, & Kaplan, Peter W. (2018). Acute Systemic Complications of Convulsive Status Epilepticus-A Systematic Review. Critical Care Medicine, 46(1), 138–145. https://doi.org/10.1097/ccm.0000000000002843

Sutter R, Dittrich TD, & Kaplan PW. (2018). Causes, Manifestations, and Complications of Generalized Convulsive Status Epilepticus in Adults. In Drislane FW; Kaplan MBBS PW (Ed.), Status Epilepticus: A Clinical Perspective (pp. 73–85). Springer International Publishing.

Rakic, Milenko, Dittrich, Tolga, Elger, Bernice S., & Shaw, David. (2017). Enhancing patients’ autonomy by involving them in research ethics committees. International Journal for Quality in Health Care, 29(7), 896–900. https://doi.org/10.1093/intqhc/mzx128

Sutter, Raoul, Dittrich, Tolga D., & Kaplan, Peter W. (2017). Causes, manifestations, and complications of generalized convulsive status epilepticus in adults. In Drislane, F. W.; Kaplan, P. W. (Ed.), Status epilepticus - clinical perspective (pp. 73–86). Springer. https://doi.org/10.1007/978-3-319-58200-9_7

Dittrich, Tolga, Tschudin-Sutter, Sarah, Widmer, Andreas F., Rüegg, Stephan, Marsch, Stephan, & Sutter, Raoul. (2016). Risk factors for new-onset delirium in patients with bloodstream infections: independent and quantitative effect of catheters and drainages-a four-year cohort study. Annals of Intensive Care, 6(1), 104. https://doi.org/10.1186/s13613-016-0205-x