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Prof. Dr. med. Ulrich A. Walker

Department of Clinical Research
Profiles & Affiliations

Publications

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Deibel, Elisabeth, Carreira, Patricia E., Vonk, Madelon, del Papa, Nicoletta, Bečvář, Radim, Guillén-Del-Castillo, Alfredo, Campochiaro, Corrado, Poormoghim, Hadi, Liem, Sophie, Lazzaroni, Maria-Grazia, Giollo, Alessandro, Mekinian, Arsène, de Vries-Bouwstra, Jeska, De Santis, Maria, Balbir-Gurman, Alexandra, Mihai, Carina, De Luca, Giacomo, Moiseev, Sergey, Zanatta, Elisabetta, et al. (2024). Does the Impact of COVID-19 on Patients With Systemic Sclerosis Change Over Time? Arthritis Care and Research, 76, 88–97. https://doi.org/10.1002/acr.25226

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Giaglis, Stavros, Daoudlarian, Douglas, Thiel, Jens, Rizzi, Marta, Kyburz, Diego, Venhoff, Nils, & Walker, Ulrich A. (2023). Mitochondrial DNA: A novel indicator of active inflammation in ANCA-Associated vasculitides. Rheumatology (United Kingdom), 62, 2930–2937. https://doi.org/10.1093/rheumatology/kead015

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Guler, Sabina, Sarbu, Adela-Cristina, Stalder, Odile, Allanore, Yannick, Bernardino, Vera, Distler, Joerg, Gabrielli, Armando, Hoffmann-Vold, Anna-Maria, Matucci-Cerinic, Marco, Müller-Ladner, Ulf, Ortiz-Santamaria, Vera, Rednic, Simona, Riccieri, Valeria, Smith, Vanessa, Ullman, Susanne, Walker, Ulrich A., Geiser, Thomas K., Distler, Oliver, Maurer, Britta, & Kollert, Florian. (2023). Phenotyping by persistent inflammation in systemic sclerosis associated interstitial lung disease: A EUSTAR database analysis. Thorax, 78, 1188–1196. https://doi.org/10.1136/thorax-2023-220541

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Lepri, Gemma, Airò, Paolo, Distler, Oliver, Andréasson, Kristofer, Braun-Moscovici, Yolanda, Hachulla, Eric, Balbir-Gurman, Alexandra, De Langhe, Ellen, Rednic, Simona, Ingegnoli, Francesca, Rosato, Edoardo, Groseanu, Laura, Ionescu, Ruxandra, Bellando-Randone, Silvia, Garzanova, Liudmila, Beretta, Lorenzo, Bellocchi, Chiara, Moiseev, Sergey, Novikov, Pavel, et al. (2023). Systemic sclerosis and primary biliary cholangitis: Longitudinal data to determine the outcomes. Journal of Scleroderma and Related Disorders, 8, 210–220. https://doi.org/10.1177/23971983231155948

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Bruni C, Heidenreich S, Duenas A, Hoffmann-Vold AM, Gabrielli A, Allanore Y, Chatelus E, Distler JHW, Hachulla E, Hsu VM, Hunzelmann N, Khanna D, Truchetet ME, Walker UA, Alves M, Schoof N, Saketkoo LA, & Distler O. (2022). Patient preferences for the treatment of systemic sclerosis-associated interstitial lung disease: a discrete choice experiment. Rheumatology (Oxford, England), 61(10), 4035–4046. https://doi.org/10.1093/rheumatology/keac126

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Iudici M., Jarlborg M., Lauper K., Muller-Ladner U., Smith V., Allanore Y., Balbir-Gurman A., Doria A., Airo P., Walker U.A., Riccieri V., Vonk M.C., Gabrielli A., Hoffmann-Vold A.-M., Szucs G., Martin T., Distler O., & Courvoisier D.S. (2022). Representativeness of systemic sclerosis patients in interventional randomized trials: An analysis of the EUSTAR database. Rheumatology (United Kingdom), 61(2), 743–755. https://doi.org/10.1093/rheumatology/keab437

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Arnold S., Jaeger V.K., Scherer A., Ciurea A, Walker U.A., & Kyburz D. (2022). Discontinuation of biologic DMARDs in a real-world population of patients with rheumatoid arthritis in remission: outcome and risk factors. Rheumatology (United Kingdom), 61(1), 131–138. https://doi.org/10.1093/rheumatology/keab343

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Mischlinger, J., Jaeger, V. K., Ciurea, A., Gabay, C., Hasler, P., Müller, R. B., Siegrist, C. A., Villiger, P., Walker, U. A., Hatz, C., & Bühler, S. (2022). Long-term persistence of antibodies after diphtheria/tetanus vaccination in immunosuppressed patients with inflammatory rheumatic diseases and healthy controls. Vaccine, 40(33), 4897–4904. https://doi.org/10.1016/j.vaccine.2022.06.013

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Ritter, Fabian, Franzeck, Fabian, Geisshardt, Julian, Walker, Ulrich A., & Osthoff, Michael. (2022). Gout Arthritis During Admission for Decompensated Heart Failure—A Descriptive Analysis of Risk Factors, Treatment and Prognosis. Frontiers in Medicine, 9. https://doi.org/10.3389/fmed.2022.789414

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Roessinger, Olivier, Hügle, Thomas, Walker, Ulrich A., & Geurts, Jeroen. (2022). Polg mtDNA mutator mice reveal limited involvement of vertebral bone loss in premature aging-related thoracolumbar hyperkyphosis [Journal-article]. Bone Reports, 17, 101618. https://doi.org/10.1016/j.bonr.2022.101618

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Giaglis S, Daoudlarian D, Voll RE, Kyburz D, Venhoff N, & Walker UA. (2021). Circulating mitochondrial DNA copy numbers represent a sensitive marker for diagnosis and monitoring of disease activity in systemic lupus erythematosus. RMD Open, 7(3). https://doi.org/10.1136/rmdopen-2021-002010

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Lechtenboehmer C.A., Burkard T., Reichenbach S., Walker U.A., Burden A.M., & Hugle T. (2021). Increased radiographic progression of distal hand osteoarthritis occurring during biologic DMARD monotherapy for concomitant rheumatoid arthritis. Arthritis Research and Therapy, 23(1). https://doi.org/10.1186/s13075-021-02654-0

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Manoil D., Courvoisier D.S., Gilbert B., Moller B., Walker U.A., Von Muehlenen I., Rubbert-Roth A., Finckh A., & Bostanci N. (2021). Associations between serum antibodies to periodontal pathogens and preclinical phases of rheumatoid arthritis. Rheumatology (United Kingdom), 60(10), 4755–4764. https://doi.org/10.1093/rheumatology/keab097

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Saketkoo L.A., Frech T., Varju C., Domsic R., Farrell J., Gordon J.K., Mihai C., Sandorfi N., Shapiro L., Poole J., Volkmann E.R., Lammi M., McAnally K., Alexanderson H., Pettersson H., Hant F., Kuwana M., Shah A.A., Smith V., et al. (2021). A comprehensive framework for navigating patient care in systemic sclerosis: A global response to the need for improving the practice of diagnostic and preventive strategies in SSc. Best Practice and Research: Clinical Rheumatology, 35(3). https://doi.org/10.1016/j.berh.2021.101707

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Hernández J, Jordan S, Dobrota R, Iudici M, Hasler P, Ribi C, Villiger P, Vlachoyiannopoulos P, Vacca A, Garzanova L, Giollo A, Rosato E, Kötter I, Carreira PE, Doria A, Henes J, Müller-Ladner U, Smith V, Distler J, et al. (2021). The burden of systemic sclerosis in Switzerland - the Swiss systemic sclerosis EUSTAR cohort. Swiss Medical Weekly, 151, w20528. https://doi.org/10.4414/smw.2021.20528

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Kalweit M., Walker U.A., Finckh A., Muller R., Kalweit G., Scherer A., Boedecker J., & Hugle T. (2021). Personalized prediction of disease activity in patients with rheumatoid arthritis using an adaptive deep neural network. PLoS ONE, 16(6 June). https://doi.org/10.1371/journal.pone.0252289

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Walker U.A., Tilson H.H., Hawkins P.N., Van Der Poll T., Noviello S., Levy J., Vritzali E., Hoffman H.M., & Kuemmerle-Deschner J.B. (2021). Long-term safety and effectiveness of canakinumab therapy in patients with cryopyrin-associated periodic syndrome: Results from the β-Confident Registry. RMD Open, 7(2). https://doi.org/10.1136/rmdopen-2021-001663

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Shaw Y., Courvoisier D.S., Scherer A., Ciurea A., Lehmann T., Jaeger V.K., Walker U.A., & Finckh A. (2021). Impact of assessing patient-reported outcomes with mobile apps on patient-provider interaction. RMD Open, 7(1). https://doi.org/10.1136/rmdopen-2021-001566

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Vonk M.C., Walker U.A., Volkmann E.R., Kreuter M., Johnson S.R., & Allanore Y. (2021). Natural variability in the disease course of SSC-ILD: Implications for treatment. European Respiratory Review, 30(159). https://doi.org/10.1183/16000617.0340-2020

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Spierings J., Van Rhenen A., Welsing P.M.W., Marijnissen A.C.A., De Langhe E., Del Papa N., Dierickx D., Gheorghe K.R., Henes J., Hesselstrand R., Kerre T., Ljungman P., Van De Loosdrecht A.A., Marijt E.W.A.F., Mayer M., Schmalzing M., Schroers R., Smith V., Voll R.E., et al. (2021). A randomised, open-label trial to assess the optimal treatment strategy in early diffuse cutaneous systemic sclerosis: The UPSIDE study protocol. BMJ Open, 11(3). https://doi.org/10.1136/bmjopen-2020-044483

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Giaglis, Stavros, Chowdhury, Chanchal Sur, van Breda, Shane Vontelin, Stoikou, Maria, Tiaden, André N., Daoudlarian, Douglas, Schaefer, Guenther, Buser, Andreas, Walker, Ulrich A., Lapaire, Olav, Hoesli, Irene, Hasler, Paul, & Hahn, Sinuhe. (2021). Circulatory neutrophils exhibit enhanced neutrophil extracellular trap formation in early puerperium: NETs at the nexus of thrombosis and immunity. International Journal of Molecular Sciences, 22. https://doi.org/10.3390/ijms222413646

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Kocher, Agnes, Ndosi, Mwidimi, Denhaerynck, Kris, Simon, Michael, Dwyer, Andrew A., Distler, Oliver, Hoeper, Kirsten, Künzler-Heule, Patrizia, Redmond, Anthony C., Villiger, Peter M., Walker, Ulrich A., & Nicca, Dunja. (2021). A rare disease patient-reported outcome measure: revision and validation of the German version of the Systemic Sclerosis Quality of Life Questionnaire (SScQoL) using the Rasch model. Orphanet Journal of Rare Diseases, 16(1), 356. https://doi.org/10.1186/s13023-021-01944-9

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Kocher, Agnes, Simon, Michael, Dwyer, Andrew A., Blatter, Catherine, Bogdanovic, Jasmina, Künzler-Heule, Patrizia, Villiger, Peter M., Dan, Diana, Distler, Oliver, Walker, Ulrich A., & Nicca, Dunja. (2021). Patient and healthcare professional eHealth literacy and needs for systemic sclerosis support: a mixed methods study. RMD Open, 7(3), e001783. https://doi.org/10.1136/rmdopen-2021-001783

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Geurts J, Nasi S., Distel P., Müller-Gerbl M, Prolla T.A., Kujoth G.C., Walker U.A., & Hügle T. (2020). Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis features. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-58385-w

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Fallet B., & Walker U.A. (2020). Current immunosuppressive and antifibrotic therapies of systemic sclerosis and emerging therapeutic strategies. Expert Review of Clinical Pharmacology, 13(11), 1203–1218. https://doi.org/10.1080/17512433.2020.1832466

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Erzer J.N., Jaeger V.K., Tikly M., & Walker U.A. (2020). Systemic sclerosis in sub-saharan Africa: A systematic review. Pan African Medical Journal, 37, 1–18. https://doi.org/10.11604/pamj.2020.37.176.22557

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Fallet B, Kyburz D, & Walker U.A. (2020). Mild Course of COVID-19 and Spontaneous Virus Clearance in a Patient With Depleted Peripheral Blood B Cells Due to Rituximab Treatment. Arthritis and Rheumatology, 72(9), 1581–1582. https://doi.org/10.1002/art.41380

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Jaeger V.K., Tikly M., Xu D., Siegert E., Hachulla E., Airo P., Valentini G., Matucci Cerinic M., Distler O., Cozzi F., Carreira P., Allanore Y., Muller-Ladner U., Ananieva L.P., Balbir-Gurman A., Distler J.H.W., Czirjak L., Li M., Henes J., et al. (2020). Racial differences in systemic sclerosis disease presentation: A European Scleroderma Trials and Research group study. Rheumatology (United Kingdom), 59(7), 1684–1694. https://doi.org/10.1093/rheumatology/kez486

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Hoffmann-Vold A.-M., Maher T.M., Philpot E.E., Ashrafzadeh A., Barake R., Barsotti S., Bruni C., Carducci P., Carreira P.E., Castellvi I., Del Galdo F., Distler J.H.W., Foeldvari I., Fraticelli P., George P.M., Griffiths B., Guillen-Del-Castillo A., Hamid A.M., Horvath R., et al. (2020). The identification and management of interstitial lung disease in systemic sclerosis: evidence-based European consensus statements. The Lancet Rheumatology, 2(2), e71–e83. https://doi.org/10.1016/s2665-9913(19)30144-4

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Blagojevic J., Abignano G., Avouac J., Cometi L., Frerix M., Bellando-Randone S., Guiducci S., Bruni C., Huscher D., Jaeger V.K., Lorand V., Maurer B., Nihtyanova S., Riemekasten G., Siegert E., Tarner I.H., Vettori S., Walker U.A., Czirjak L., et al. (2020). Use of vasoactive/vasodilating drugs for systemic sclerosis (SSc)-related digital ulcers (DUs) in expert tertiary centres: results from the analysis of the observational real-life DeSScipher study. Clinical Rheumatology, 39(1), 27–36. https://doi.org/10.1007/s10067-019-04564-8

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Burkhard, J., Ciurea, A., Gabay, C., Hasler, P., Müller, R., Niedrig, M., Fehr, J., Villiger, P., Visser, L. G., de Visser, A. W., Walker, U. A., Hatz, C., & Bühler, S. (2020). Long-term immunogenicity after yellow fever vaccination in immunosuppressed and healthy individuals. Vaccine, 38(19), 3610–3617. https://doi.org/10.1016/j.vaccine.2019.12.042

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Kingston C., Zech G., Pauli C., & Walker U. (2020). Lumbar Radiculitis as a Complication of Vaccination against Tick-Borne Encephalitis: A Differential Diagnosis of Low Back Pain and Nerve Root Compression. Case Reports in Medicine, 2020. https://doi.org/10.1155/2020/6130364

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Schmid, N., Ciurea, A., Gabay, C., Hasler, P., Fehr, J., Müller, R., Villiger, P., Walker, U., Hatz, C., & Bühler, S. (2020). Travel patterns, risk behaviour and health problems of travellers with rheumatic diseases compared to controls: a multi-centre, observational study. Travel Med Infect Dis, 38, 101818. https://doi.org/10.1016/j.tmaid.2020.101818

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Fasano S., Riccardi A., Messiniti V., Caramaschi P., Rosato E., Maurer B., Smith V., Siegert E., De Langhe E., Riccieri V., Airo P., Mihai C., Avouac J., Zanatta E., Walker U.A., Iannone F., Garcia De La Pena Lefebvre P., Distler J.H.W., Vacca A., et al. (2019). Revised European Scleroderma Trials and Research Group Activity Index is the best predictor of short-term severity accrual. Annals of the Rheumatic Diseases, 78(12), 1681–1685. https://doi.org/10.1136/annrheumdis-2019-215787

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Jaeger VK, Lebrecht D, Nicholson AG, Wells A, Bhayani H, Gazdhar A, Tamm M., Venhoff N., Geiser T., & Walker U.A. (2019). Mitochondrial DNA mutations and respiratory chain dysfunction in idiopathic and connective tissue disease-related lung fibrosis. Scientific Reports, 9(1). https://doi.org/10.1038/s41598-019-41933-4

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Jaeger V.K., & Walker U.A. (2019). Raynaud’s phenomenon: no net effects of vasodilators in a network analysis. The Lancet Rheumatology, 1(4), e200–e202. https://doi.org/10.1016/s2665-9913(19)30109-2

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Smith V., Vanhaecke A., Herrick A.L., Distler O., Guerra M.G., Denton C.P., Deschepper E., Foeldvari I., Gutierrez M., Hachulla E., Ingegnoli F., Kubo S., Muller-Ladner U., Riccieri V., Sulli A., van Laar J.M., Vonk M.C., Walker U.A., & Cutolo M. (2019). Fast track algorithm: How to differentiate a “scleroderma pattern” from a “non-scleroderma pattern”. Autoimmunity Reviews, 18(11). https://doi.org/10.1016/j.autrev.2019.102394

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Valentini G., Huscher D., Riccardi A., Fasano S., Irace R., Messiniti V., Matucci-Cerinic M., Guiducci S., Distler O., Maurer B., Avouac J., Tarner I.H., Frerix M., Riemekasten G., Siegert E., Czirjak L., Lorand V., Denton C.P., Nihtyanova S., et al. (2019). Vasodilators and low-dose acetylsalicylic acid are associated with a lower incidence of distinct primary myocardial disease manifestations in systemic sclerosis: results of the DeSScipher inception cohort study. Annals of the Rheumatic Diseases, 78(11), 1576–1582. https://doi.org/10.1136/annrheumdis-2019-215486

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Becker M., Graf N., Sauter R., Allanore Y., Curram J., Denton C.P., Khanna D., Matucci-Cerinic M., de Oliveira Pena J., Pope J.E., Distler O., Guiducci S., Walker U., Jaeger V., Bannert B., Lapadula G., Becvarare R., Cutolo M., Valentini G., et al. (2019). Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: A European Scleroderma Trials and Research (EUSTAR) analysis. Annals of the Rheumatic Diseases, 78(9), 1242–1248. https://doi.org/10.1136/annrheumdis-2019-215145

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Bratu VA, Häusermann P, Walker UA, Daikeler T, Zubler V, Jaeger VK, Weber U, & Studler U. (2019). Do Patients With Skin Psoriasis Show Subclinical Axial Inflammation on Magnetic Resonance Imaging of the Sacroiliac Joints and Entire Spine? Arthritis Care and Research, 71(8), 1109–1118. https://doi.org/10.1002/acr.23767

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Wu W., Jordan S., Graf N., de Oliveira Pena J., Curram J., Allanore Y., Matucci-Cerinic M., Pope J.E., Denton C.P., Khanna D., Distler O., Guiducci S., Walker U., Jaeger V., Bannert B., Lapadula G., Becvarare R., Cutolo M., Valentini G., et al. (2019). Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the european scleroderma trials and research (eustar) cohort. Annals of the Rheumatic Diseases, 78(5), 648–656. https://doi.org/10.1136/annrheumdis-2018-213455

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Osthoff M, Jaeger VK, Heijnen IAFM, Trendelenburg M, Jordan S, Distler O, & Walker U.A. (2019). Role of lectin pathway complement proteins and genetic variants in organ damage and disease severity of systemic sclerosis: A cross-sectional study. Arthritis Research and Therapy, 21(1). https://doi.org/10.1186/s13075-019-1859-1

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Blagojevic J., Bellando-Randone S., Abignano G., Avouac J., Cometi L., Czirjak L., Denton C.P., Distler O., Frerix M., Guiducci S., Huscher D., Jaeger V.K., Lorand V., Maurer B., Nihtyanova S., Riemekasten G., Siegert E., Tarner I.H., Vettori S., et al. (2019). Classification, categorization and essential items for digital ulcer evaluation in systemic sclerosis: A DeSScipher/European Scleroderma Trials and Research group (EUSTAR) survey. Arthritis Research and Therapy, 21(1). https://doi.org/10.1186/s13075-019-1822-1

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Carreira PE, Carmona L, Joven BE, Loza E, Andréu JL, Riemekasten G, Vettori S, Balbir-Gurman A, Airò P, Walker U, Damjanov N, Matucci-Cerinic M, Ananieva LP, Rednic S, Czirják L, Distler O, Farge D, Hesselstrand R, Corrado A, et al. (2019). Differences associated with age at onset in early systemic sclerosis patients: a report from the EULAR Scleroderma Trials and Research Group (EUSTAR) database. Scandinavian Journal of Rheumatology, 48(1), 42–51. https://doi.org/10.1080/03009742.2018.1459830

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Bühler, Silja, Jaeger, Veronika Katharina, Adler, Sabine, Bannert, Bettina, Brümmerhoff, Carolin, Ciurea, Adrian, Distler, Oliver, Franz, Juliane, Gabay, Cem, Hagenbuch, Niels, Herzog, Christian, Hasler, Paul, Kling, Kerstin, Kyburz, Diego, Müller, Rüdiger, Nissen, Michael John, Siegrist, Claire-Anne, Villiger, Peter Matthias, Walker, Ulrich A., & Hatz, Christoph. (2019). Safety and immunogenicity of tetanus/diphtheria vaccination in patients with rheumatic diseases-a prospective multi-centre cohort study. Rheumatology, 58(9), 1585–1596. https://doi.org/10.1093/rheumatology/kez045

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Lechtenboehmer CA, Jaeger VK, Kyburz D, Walker UA, & Hügle T. (2019). Brief Report: Influence of Disease Activity in Rheumatoid Arthritis on Radiographic Progression of Concomitant Interphalangeal Joint Osteoarthritis. Arthritis and Rheumatology, 71(1), 43–49. https://doi.org/10.1002/art.40684

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Jaeger VK, Valentini G, Hachulla E, Cozzi F, Distler O, Airó P, Czirják L, Allanore Y, Siegert E, Rosato E, Matucci-Cerinic M, Caimmi C, Henes J, Carreira PE, Smith V, Del Galdo F, Denton CP, Ullman S, De Langhe E, et al. (2018). Brief Report: Smoking in Systemic Sclerosis: A Longitudinal European Scleroderma Trials and Research Group Study. Arthritis & rheumatology (Hoboken, N.J.), 70(11), 1829–1834. https://doi.org/10.1002/art.40557

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Walker UA, Jaeger VK, Bruppacher KM, Dobrota R, Arlettaz L, Banyai M, Beron J, Chizzolini C, Groechenig E, Mueller RB, Spertini F, Villiger PM, & Distler O. (2018). Prospective evaluation of the capillaroscopic skin ulcer risk index in systemic sclerosis patients in clinical practice: a longitudinal, multicentre study. Arthritis research & therapy, 20(1), 239. https://doi.org/10.1186/s13075-018-1733-6

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Carreira PE, Carmona L, Joven BE, Loza E, Andreu JL, Riemekasten G, Vettori S, Balbir-Gurman A, Airò P, Walker UA, Damjanov N, Matucci-Cerinic M, Ananieva LP, Rednic S, Czirják L, Distler O, Farge D, Hesselstrand R, Corrado A, et al. (2018). Gender differences in early systemic sclerosis patients: a report from the EULAR scleroderma trials and research group (EUSTAR) database. Clinical and experimental rheumatology, 36 Suppl 113(4), 68–75.

Walker UA, Luetke Volksbeck S, & Kuemmerle-Deschner J. (2018). Flare of a Cryopyrin-associated Periodic Syndrome Following Vaccination with Neisseria Meningitidis Polysaccharides. (Patent No. 6). 45(6), Article 6. https://doi.org/10.3899/jrheum.171037

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Beyer C, Huscher D, Ramming A, Bergmann C, Avouac J, Guiducci S, Meier F, Vettori S, Siegert E, Jaeger VK, Maurer B, Riemekasten G, Walker U, Müller-Ladner U, Valentini G, Matucci-Cerinic M, Allanore Y, Distler O, Schett G, & Distler JHW. (2018). Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis. Annals of the rheumatic diseases, 77(4), 626–628. https://doi.org/10.1136/annrheumdis-2016-210834

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Jaeger VK, Distler O, Maurer B, Czirják L, Lóránd V, Valentini G, Vettori S, Del Galdo F, Abignano G, Denton C, Nihtyanova S, Allanore Y, Avouac J, Riemekasten G, Siegert E, Huscher D, Matucci-Cerinic M, Guiducci S, Frerix M, et al. (2018). Functional disability and its predictors in systemic sclerosis: a study from the DeSScipher project within the EUSTAR group. Rheumatology (Oxford, England), 57(3), 441–450. https://doi.org/10.1093/rheumatology/kex182

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Adler S, Huscher D, Siegert E, Allanore Y, Czirják L, DelGaldo F, Denton CP, Distler O, Frerix M, Matucci-Cerinic M, Mueller-Ladner U, Tarner IH, Valentini G, Walker UA, Villiger PM, Riemekasten G, & EUSTAR co-workers on behalf of the DeSScipher project research group within the EUSTAR network. (2018). Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group. Arthritis research & therapy, 20(1), 17. https://doi.org/10.1186/s13075-018-1517-z

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Johnson SR, Soowamber ML, Fransen J, Khanna D, Van Den Hoogen F, Baron M, Matucci-Cerinic M, Denton CP, Medsger TA Jr, Carreira PE, Riemekasten G, Distler J, Gabrielli A, Steen V, Chung L, Silver R, Varga J, Müller-Ladner U, Vonk MC, et al. (2018). There is a need for new systemic sclerosis subset criteria. A content analytic approach. Scandinavian journal of rheumatology, 47(1), 62–70. https://doi.org/10.1080/03009742.2017.1299793

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Walker UA, Saketkoo LA, & Distler O. (2018). Haematopoietic stem cell transplantation in systemic sclerosis. RMD open, 4(1), e000533. https://doi.org/10.1136/rmdopen-2017-000533

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Elhai M, Meune C, Boubaya M, Avouac J, Hachulla E, Balbir-Gurman A, Riemekasten G, Airò P, Joven B, Vettori S, Cozzi F, Ullman S, Czirják L, Tikly M, Müller-Ladner U, Caramaschi P, Distler O, Iannone F, Ananieva LP, et al. (2017). Mapping and predicting mortality from systemic sclerosis. Annals of the rheumatic diseases, 76(11), 1897–1905. https://doi.org/10.1136/annrheumdis-2017-211448

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Walker UA. (2017). Trial of Tocilizumab in Giant-Cell Arteritis. (Patent No. 15). 377(15), Article 15. https://doi.org/10.1056/nejmc1711031

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Jaeger, Veronika K., Barmet, Anna, Schiffer, Pia, Zufferey, Pascal, Badaracco, Andrea, Walder, Marcel, Dudler, Jean, Frey, Dieter, Mueller, Franziska, Pichler, Lilian, Voss, Peter, Bosia, Lorenzo, & Walker, Ulrich A. (2017). Patient’s Self-Monitoring of Disease Activity of Rheumatic Diseases Via Webapp - Study Design, Patient’s Perspective and Recruitment in the First 16 Months of a Swiss Multicentre, Longitudinal Study. 69. WILEY.

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Jaeger, Veronika K., Lebrecht, Dirk, Nicholson, Andrew G., Wells, Athol U., George, Suresh, Gazdhar, Amiq, Tamm, Michael, Venhoff, Nils, Geiser, Thomas, & Walker, Ulrich A. (2017). Mitochondrial DNA Mutations and Respiratory Chain Dysfunction in Lung Fibrosis of Systemic Sclerosis. 69. WILEY.

Walker UA, Mueller RB, Jaeger VK, Theiler R, Forster A, Dufner P, Ganz F, & Kyburz D. (2017). Disease activity dynamics in rheumatoid arthritis: patients’ self-assessment of disease activity via WebApp. Rheumatology (Oxford, England), 56(10), 1707–1712. https://doi.org/10.1093/rheumatology/kex229

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Allanore Y, Distler O, Walker UA, Khanna D, Furst DE, & Meune C. (2017). Points to consider when doing a trial primarily involving the heart. Rheumatology (Oxford, England), 56(suppl_5), v12–v16. https://doi.org/10.1093/rheumatology/kex198

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Alpizar-Rodriguez D, Mueller RB, Möller B, Dudler J, Ciurea A, Zufferey P, Kyburz D, Walker UA, von Mühlenen I, Roux-Lombard P, Mahler M, Lamacchia C, Courvoisier DS, Gabay C, & Finckh A. (2017). Female hormonal factors and the development of anti-citrullinated protein antibodies in women at risk of rheumatoid arthritis. Rheumatology (Oxford, England), 56(9), 1579–1585. https://doi.org/10.1093/rheumatology/kex239

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Carreira PE, Carmona L, Joven BE, Loza E, Andreu JL, Riemekasten G, Vettori S, Allanore Y, Balbir-Gurman A, Airò P, Walker UA, Damjanov N, Ananieva LP, Rednic S, Czirják L, Distler O, Farge D, Hesselstrand R, Corrado A, et al. (2017). Clinical determinants of elevated systolic pulmonary artery pressure measured by transthoracic Doppler echocardiography in early systemic sclerosis. Clinical and experimental rheumatology, 35 Suppl 106(4), 114–121.

Jaeger VK, Hoffman HM, van der Poll T, Tilson H, Seibert J, Speziale A, Junge G, Franke K, Vritzali E, Hawkins PN, Kuemmerle-Deschner J, & Walker UA. (2017). Safety of vaccinations in patients with cryopyrin-associated periodic syndromes: a prospective registry based study. (Patent No. 9). 56(9), Article 9. https://doi.org/10.1093/rheumatology/kex185

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Walker UA, Clements PJ, Allanore Y, Distler O, Oddis CV, Khanna D, & Furst DE. (2017). Muscle involvement in systemic sclerosis: points to consider in clinical trials. Rheumatology (Oxford, England), 56(suppl_5), v38–v44. https://doi.org/10.1093/rheumatology/kex196

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Keck, A. D., Jaeger, V. K., & Walker, U. A. (2017). Myositis in Systemic Sclerosis, Lupus Erythematosus and Sjogren’s Syndrome. AKTUELLE RHEUMATOLOGIE, 42, 310–315. https://doi.org/10.1055/s-0042-112361

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Landmann EC, & Walker UA. (2017). Pharmacological treatment options for cryopyrin-associated periodic syndromes. Expert review of clinical pharmacology, 10(8), 855–864. https://doi.org/10.1080/17512433.2017.1338946

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Blagojevic, J., Cometi, L., Abignano, G., Guiducci, S., Bellando-Randone, S., Huscher, D., Avouac, J., Czirjak, L., Denton, C., Distler, O., Frerix, M., Jaeger, V. K., Lorand, V., Maurer, B., Nihtyanova, S., Riemekasten, G., Siegert, E., Valentini, G., Vettori, S., et al. (2017). CLASSIFICATION, CATEGORISATION AND ESSENTIAL ITEMS FOR DIGITAL ULCER (DU) EVALUATION IN SYSTEMIC SCLEROSIS (SSC): A DESSCIPHER/EUSTAR SURVEY [BMJ PUBLISHING GROUP]. 76, 915. https://doi.org/10.1136/annrheumdis-2017-eular.6815

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Jaeger, V. K., Hoffmann, H. M., van der Poll, T., Tilson, H., Seibert, J., Speziale, A., Junge, G., Franke, K., Vritzali, E., Hawkins, P. N., Kuemmerle-Deschner, J., & Walker, U. A. (2017). FREQUENT, UNUSUALLY SEVERE, LONG LASTING, LOCAL AND SYSTEMIC PNEUMOCOCCAL VACCINE REACTIONS IN PATIENTS WITH CRYOPYRIN-ASSOCIATED PERIODIC SYNDROMES (CAPS): RESULTS OF A PROSPECTIVE REGISTRY BASED STUDY [BMJ PUBLISHING GROUP]. 76, 710–711. https://doi.org/10.1136/annrheumdis-2017-eular.1513

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Jaeger, V. K., Valentini, G., Hachulla, E., Czirjak, L., Siegert, E., Distler, O., Bambara, L. M., Rosato, E., Allanore, Y., Matucci-Cerinic, M., Airo, P., & Walker, U. (2017). SMOKING BEHAVIOUR AND THE PROGRESSION OF ORGAN MANIFESTATIONS IN SYSTEMIC SCLEROSIS: A LONGITUDINAL EUROPEAN SCLERODERMA TRIALS AND RESEARCH GROUP STUDY [BMJ PUBLISHING GROUP]. 76, 909–910. https://doi.org/10.1136/annrheumdis-2017-eular.2729

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Walker, U. A., Jaeger, V. K., Arlettaz, L., Banyai, M., Beron, J., Chizzolini, C., Groechenig, E., Mueller, R. B., Spertini, F., Villiger, P., & Distler, O. (2017). PROSPECTIVE EVALUATION OF THE CAPILLAROSCOPIC SKIN ULCER INDEX (CSURI) IN CLINICAL PRACTICE [BMJ PUBLISHING GROUP]. 76, 626–627. https://doi.org/10.1136/annrheumdis-2017-eular.1827

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Alpizar-Rodriguez D, Brulhart L, Mueller RB, Möller B, Dudler J, Ciurea A, Walker UA, Von Mühlenen I, Kyburz D, Zufferey P, Mahler M, Bas S, Gascon D, Lamacchia C, Roux-Lombard P, Lauper K, Nissen MJ, Courvoisier DS, Gabay C, & Finckh A. (2017). The prevalence of anticitrullinated protein antibodies increases with age in healthy individuals at risk for rheumatoid arthritis. Clinical rheumatology, 36(3), 677–682. https://doi.org/10.1007/s10067-017-3547-3

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Kowal-Bielecka, Otylia, Fransen, Jaap, Avouac, Jerome, Becker, Mike, Kulak, Agnieszka, Allanore, Yannick, Distler, Oliver, Clements, Philip, Cutolo, Maurizio, Czirjak, Laszlo, Damjanov, Nemanja, Del Galdo, Francesco, Denton, Christopher P., Distler, Jörg H. W., Foeldvari, Ivan, Figelstone, Kim, Frerix, Marc, Furst, Daniel E., Guiducci, Serena, et al. (2017). Update of EULAR recommendations for the treatment of systemic sclerosis. Annals of the Rheumatic Diseases, 76(8), 1327–1339. https://doi.org/10.1136/annrheumdis-2016-209909

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Valentini G, Iudici M, Walker UA, Jaeger VK, Baron M, Carreira P, Czirják L, Denton CP, Distler O, Hachulla E, Herrick AL, Kowal-Bielecka O, Pope J, Müller-Ladner U, Riemekasten G, Avouac J, Frerix M, Jordan S, Minier T, et al. (2017). The European Scleroderma Trials and Research group (EUSTAR) task force for the development of revised activity criteria for systemic sclerosis: derivation and validation of a preliminarily revised EUSTAR activity index. (Patent No. 1). 76(1), Article 1. https://doi.org/10.1136/annrheumdis-2016-209768

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Loetscher J, Fistarol S, & Walker UA. (2016). Pyoderma Gangrenosum and Erythema Nodosum Revealing Takayasu’s Arteritis. (No. 3; Vol. 8, pp. 354–357). https://doi.org/10.1159/000452829

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Jaeger VK, & Walker UA. (2016). Erectile Dysfunction in Systemic Sclerosis. Current rheumatology reports, 18(8), 49. https://doi.org/10.1007/s11926-016-0597-5

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Wirz EG, Jaeger VK, Allanore Y, Riemekasten G, Hachulla E, Distler O, Airò P, Carreira PE, Tikly M, Vettori S, Balbir Gurman A, Damjanov N, Müller-Ladner U, Distler J, Li M, Häusermann P, Walker UA, & EUSTAR coauthors. (2016). Incidence and predictors of cutaneous manifestations during the early course of systemic sclerosis: a 10-year longitudinal study from the EUSTAR database. Annals of the rheumatic diseases, 75(7), 1285–1292. https://doi.org/10.1136/annrheumdis-2015-207271

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Mihai C, Landewé R, van der Heijde D, Walker UA, Constantin PI, Gherghe AM, Ionescu R, Rednic S, Allanore Y, Avouac J, Czirják L, Hachulla E, Riemekasten G, Cozzi F, Airò P, Cutolo M, Mueller-Ladner U, Matucci-Cerinic M, & EUSTAR co-authors. (2016). Digital ulcers predict a worse disease course in patients with systemic sclerosis. Annals of the rheumatic diseases, 75(4), 681–686. https://doi.org/10.1136/annrheumdis-2014-205897

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Walker UA. (2016). Immunomodulation of rheumatologic disorders with non-biologic disease modifying antirheumtic drugs. Seminars in hematology, 53 Suppl 1, S58–60. https://doi.org/10.1053/j.seminhematol.2016.04.017

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Walker UA, Hoffman HM, Williams R, Kuemmerle-Deschner J, & Hawkins PN. (2016). Brief Report: Severe Inflammation Following Vaccination Against Streptococcus pneumoniae in Patients With Cryopyrin-Associated Periodic Syndromes. (Patent No. 2). 68(2), Article 2. https://doi.org/10.1002/art.39482

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Walker UA, Jaeger VK, Chatzidionysiou K, Hetland ML, Hauge EM, Pavelka K, Nordström DC, Canhão H, Tomšič M, van Vollenhoven R, & Gabay C. (2016). Rituximab done: what’s next in rheumatoid arthritis? A European observational longitudinal study assessing the effectiveness of biologics after rituximab treatment in rheumatoid arthritis. (Patent No. 2). 55(2), Article 2. https://doi.org/10.1093/rheumatology/kev297

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Avouac J, Walker UA, Hachulla E, Riemekasten G, Cuomo G, Carreira PE, Caramaschi P, Ananieva LP, Matucci-Cerinic M, Czirjak L, Denton C, Ladner UM, Allanore Y, EUSTAR collaborators*, & EUSTAR collaborators. (2016). Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study. Annals of the rheumatic diseases, 75(1), 103–109. https://doi.org/10.1136/annrheumdis-2014-205295

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Elhai M, Avouac J, Walker UA, Matucci-Cerinic M, Riemekasten G, Airò P, Hachulla E, Valentini G, Carreira PE, Cozzi F, Balbir Gurman A, Braun-Moscovici Y, Damjanov N, Ananieva LP, Scorza R, Jimenez S, Busquets J, Li M, Müller-Ladner U, et al. (2016). A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study. Annals of the rheumatic diseases, 75(1), 163–169. https://doi.org/10.1136/annrheumdis-2014-206386

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Jaeger VK, Wirz EG, Allanore Y, Rossbach P, Riemekasten G, Hachulla E, Distler O, Airò P, Carreira PE, Balbir Gurman A, Tikly M, Vettori S, Damjanov N, Müller-Ladner U, Distler JH, Li M, Walker UA, & EUSTAR co-authors. (2016). Incidences and Risk Factors of Organ Manifestations in the Early Course of Systemic Sclerosis: A Longitudinal EUSTAR Study. PloS one, 11(10), e0163894. https://doi.org/10.1371/journal.pone.0163894

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Jordan S., Distler J., Maurer B., Walker U.A., Huscher D., Allanore Y., Riemekasten G., & Distler O. (2016). Effect of endothelin-1 receptor antagonists on skin fibrosis in scleroderma patients from the EUSTAR database. Journal of Scleroderma and Related Disorders, 1(2), 220–225. https://doi.org/10.5301/jsrd.5000204

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Partovi S, Kaspar M, Aschwanden M, Robbin MR, Bilecen D, Walker UA, & Staub D. (2016). Quantitative dynamic contrast-enhanced ultrasound for the functional evaluation of the skeletal muscle microcirculation in systemic sclerosis. Clinical Hemorheology and Microcirculation, 62(1), 35–44. https://doi.org/10.3233/ch-151929

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Ingegnoli F., Boracchi P., Gualtierotti R., Smith V., Cutolo M., Foeldvari I., Airo P., Alegre-Sancho J.J., Allanore Y., Ananieva L.P., Ancuta C., Andrade L.E., Aringer M., Becvar R., Bojinca M., Butrimiene I., Cantatore F.P., Caporali R., Caramaschi P., et al. (2015). A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis: A EUSTAR exploratory study. Microvascular Research, 102, 19–24. https://doi.org/10.1016/j.mvr.2015.07.007

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Maurer B, & Walker UA. (2015). Role of MRI in diagnosis and management of idiopathic inflammatory myopathies. Current rheumatology reports, 17(11), 67. https://doi.org/10.1007/s11926-015-0544-x

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Brand M, Hollaender R, Rosenberg D, Scott M, Hunsche E, Tyndall A, Denaro V, Carreira P, Varju C, Gabrielli B, Zingarelli S, Caramaschi P, Simic-Pasalic K, Müller-Ladner U, Vasile M, Mihai C, Rosato E, Vacca A, Zenone T, et al. (2015). An observational cohort study of patients with newly diagnosed digital ulcer disease secondary to systemic sclerosis registered in the EUSTAR database. Clinical and experimental rheumatology, 33(4 Suppl 91), S47–54.

Hachulla E, Clerson P, Airò P, Cuomo G, Allanore Y, Caramaschi P, Rosato E, Carreira PE, Riccieri V, Sarraco M, Denton CP, Riemekasten G, Pozzi MR, Zeni S, Mihai CM, Ullman S, Distler O, Rednic S, Smith V, et al. (2015). Value of systolic pulmonary arterial pressure as a prognostic factor of death in the systemic sclerosis EUSTAR population. Rheumatology (Oxford, England), 54(7), 1262–1269. https://doi.org/10.1093/rheumatology/keu450

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Nemec M, Pradella M, Jahn K, Tamm M, & Walker UA. (2015). Magnetic Resonance Imaging-Confirmed Pleuritis in Systemic Lupus Erythematosus-Associated Shrinking Lung Syndrome. Arthritis & Rheumatology (Hoboken, N.J.), 67(7), 1880. https://doi.org/10.1002/art.39141

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Jordan S., Distler J.H.W., Maurer B., Huscher D., Van Laar J.M., Allanore Y., Distler O., Kvien T.K., Airo P., Sancho J.J.A., Ananjeva L., Ancuta C.M., Aringer M., Balbir-Gurman A., Cantatore F.P., Caramaschi P., Chatelus E., Codullo V., Farge-Bancel D., et al. (2015). Effects and safety of rituximab in systemic sclerosis: An analysis from the European Scleroderma Trial and Research (EUSTAR) group. Annals of the Rheumatic Diseases, 74(6), 1188–1194. https://doi.org/10.1136/annrheumdis-2013-204522

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Aringer M, Müller-Ladner U, Burkhardt H, Distler JH, Distler O, Graninger WB, Günther C, Hunzelmann N, Kiener H, Sticherling M, Sunderkötter C, Walker UA, & Riemekasten G. (2015). [Common German language nomenclature for systemic sclerosis]. Zeitschrift fur Rheumatologie, 74(2), 100–103. https://doi.org/10.1007/s00393-014-1550-5

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Aschwanden M, Imfeld S, Staub D, Baldi T, Walker UA, Berger CT, Hess C, & Daikeler T. (2015). The ultrasound compression sign to diagnose temporal giant cell arteritis shows an excellent interobserver agreement. Clinical and experimental rheumatology, 33(2 Suppl 89), S–113.

Broz P., Aschwanden M, Partovi S., Schulte A.-C., Benz D., Takes M., Walker U.A., Bilecen D, Jaeger K.A., & Imfeld S. (2015). Assessment of cutaneous microcirculation in unaffected skin regions by transcutaneous oxygen saturation monitoring and Laser Doppler flowmetry in systemic sclerosis. Clinical Hemorheology and Microcirculation, 60(3), 263–271. https://doi.org/10.3233/ch-131676

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Khanna D, Furst DE, Allanore Y, Bae S, Bodukam V, Clements PJ, Cutolo M, Czirjak L, Denton CP, Distler O, Walker UA, Matucci-Cerinic M, Müller-Ladner U, Seibold JR, Singh M, & Tyndall A. (2015). Twenty-two points to consider for clinical trials in systemic sclerosis, based on EULAR standards. Rheumatology (Oxford, England), 54(1), 144–151. https://doi.org/10.1093/rheumatology/keu288

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Maurer B., Graf N., Michel B.A., Muller-Ladner U., Czirjak L., Denton C.P., Tyndall A., Metzig C., Lanius V., Khanna D., Distler O., Tarner I.H., Cerinic M.M., Guiducci S., Walker U., Lapadula G., Iannone F., Becvar R., Sierakowsky S., et al. (2015). Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database. Annals of the Rheumatic Diseases, 74(6), 1124–1131. https://doi.org/10.1136/annrheumdis-2014-205226

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Sandmeier, B., Jaeger, V. K., Nagy, G., Carreira, P. E., Tzankov, A., Widuchowska, M., Antic, M., Distler, O., Reichert, H., Distler, J. H. W., Walker, U. A., & Huegle, T. (2015). Autopsy versus clinical findings in patients with systemic sclerosis in a case series from patients of the EUSTAR database. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 33, S75–S79.

Minier T, Guiducci S, Bellando-Randone S, Bruni C, Lepri G, Czirják L, Distler O, Walker UA, Fransen J, Allanore Y, Denton C, Cutolo M, Tyndall A, Müller-Ladner U, Matucci-Cerinic M, EUSTAR co-workers, & EUSTAR co-workers. (2014). Preliminary analysis of the very early diagnosis of systemic sclerosis (VEDOSS) EUSTAR multicentre study: evidence for puffy fingers as a pivotal sign for suspicion of systemic sclerosis. (Patent No. 12). 73(12), Article 12. https://doi.org/10.1136/annrheumdis-2013-203716

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Partovi S, Schulte AC, Staub D, Jacobi B, Aschwanden M, Walker U.A., Imfeld S, Broz P, Benz D, Zipp L, Takes M, Jäger KA, Huegli RW, & Bilecen D. (2014). Correlation of skeletal muscle blood oxygenation level-dependent MRI and skin laser Doppler flowmetry in patients with systemic sclerosis. Journal of Magnetic Resonance Imaging : JMRI, 40(6), 1408–1413. https://doi.org/10.1002/jmri.24503

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