Prof. Dr. med. Christian Nickel

Benhamou, Jonathan, Nieves-Ortega, Ricardo, Nickel, Christian H., Lampart, Alina, Kuster, Tobias, Balestra, Gianmarco M., Rosin, Christiane, Becker, Christoph, Lippay, Kriemhild, & Bingisser, Roland. (2025). Human neutrophil lipocalin, procalcitonin, c-reactive protein, and leucocyte count for prediction of bacterial sepsis in emergency department patients. Scandinavian Journal of Trauma Resuscitation and Emergency Medicine, 33. https://doi.org/10.1186/s13049-025-01429-9

Raven, Wouter, Candel, Bart G.J., Wali, Nabila, Gaakeer, Menno I., Avest, Ewoud Ter, Sir, Ozcan, Lameijer, Heleen, Hessels, Roger A.P.A., Reijnen, Resi, Nickel, Christian H., de Jonge, Evert, van Zwet, Erik, & de Groot, Bas. (2025). Comparison of Standardized Mortality Ratios in seven Dutch EDs based on presenting complaints. BMC Emergency Medicine, 25. https://doi.org/10.1186/s12873-025-01200-4

Stock, Elisabeth, Vinogradova, Olga, Wangmo, Tenzin, Nickel, Christian H, Martani, Andrea, & Elger, Bernice S. (2025). Ethical perspectives on pre-hospital triage mechanisms among Swiss healthcare stakeholders during times of medical resource scarcity: A qualitative study [Journal-article]. Clinical Ethics. https://doi.org/10.1177/14777509251372983

Brunkert, Thekla, Pfundstein, Isabel, Nickel, Christian H., Lampert, Markus L., Trutschel, Diana, & Mauthner, Oliver. (2025). AdvantAGE: Implementation and Evaluation of an Interprofessional Transitional Care Model for Frail Older Adults—Protocol of an Effectiveness–Implementation Hybrid Study. Journal of Advanced Nursing, 81, 5130–5142. https://doi.org/10.1111/jan.16745

Brabrand, Mikkel, Fløjstrup, Marianne, Bogh, Søren Bie, Cooksley, Tim, & Nickel, Christian Hans. (2025). Utilizing D-dimer levels for predicting survival probability in unplanned hospital admissions: Insights from a 5-year nationwide population-based register study. European Journal of Internal Medicine, 137, 149–151. https://doi.org/10.1016/j.ejim.2025.02.026

Meyer, Jakob, Gosert, Rainer, Bingisser, Roland, Nickel, Christian H., Tschudin-Sutter, Sarah, & Leuzinger, Karoline. (2025). Diagnostic Performance of a Combined Rapid Antigen Test for Detecting SARS-CoV-2, Influenza Virus, and Respiratory Syncytial Virus in Symptomatic Patients in Tertiary Care. Journal of Medical Virology, 97. https://doi.org/10.1002/jmv.70493

Dittrich, Tolga D, Nguyen, Anh, Sporns, Peter B, Toebak, Anna M, Kriemler, Lilian F, Rudin, Salome, Zietz, Annaelle, Wagner, Benjamin, Barinka, Filip, Hänsel, Martin, Gensicke, Henrik, Sutter, Raoul, Nickel, Christian H, Katan, Mira, Peters, Nils, Michels, Lars, Kulcsár, Zsolt, Karwacki, Grzegorz M, Pileggi, Marco, et al. (2025). Large ischemic core defined by visually assessed ASPECTS predicts functional outcomes comparably accurate to automated CT perfusion in the 6–24 h window. European Stroke Journal, 10, 552–559. https://doi.org/10.1177/23969873241286691

Ünlü, Luca, Stephan, Frank-Peter, Riede, Florian N., Mettler, Annette Christine, Dutilh, Gilles, Capoferri, Gioele, Bosia, Tito, Sticherling, Christian, Bingisser, Roland, & Nickel, Christian H. (2025). Diagnostic accuracy of emergency department ECGs in hyperkalemia detection: A cross-sectional study. European Journal of Internal Medicine, 136, 56–62. https://doi.org/10.1016/j.ejim.2025.03.038

Van Oppen, James D., De Groot, Bas, Nickel, Christian H., & Beil, Michael. (2025). ABCDE-Frailty for critical presentations: Summary of the 2025 ESICM expert consensus recommendations. European Journal of Emergency Medicine, 32, 158–159. https://doi.org/10.1097/MEJ.0000000000001227

Ünlü, Luca, Margenfeld, Felix, Zendehdel, Adib, Griese, Johannes A., Poilliot, Amélie, Müller-Gerbl, Magdalena, Nickel, Christian H., & Dedic, Mirza. (2025). Ultrasound-guided Emergency Pericardiocentesis Simulation on Human Cadavers: A Scoping Review. Western Journal of Emergency Medicine, 26(3), 685–691. https://doi.org/10.5811/westjem.39696

Damke, Kristian, Lowinski, Anna, Friederich, Maike, Grosse, Gerrit M., & Nickel, Christian H. (2025). Woman With Unilateral Facial Paleness. Annals of Emergency Medicine, 85, 364–365. https://doi.org/10.1016/j.annemergmed.2024.10.009

Degen, Bojana, Szczesna, Anna, Nickel, Christian H, Bingisser, Roland, Gaab, Jens, & Minotti, Bruno. (2025). Open-label placebo for non-specific pain in the emergency department (OLP EM): study protocol for a mixed-method randomised control feasibility study in Switzerland. BMJ Open, 15. https://doi.org/10.1136/bmjopen-2024-090508

Scotti, Barbara, Szczesna, Anna, Nickel, Christian H, Degen, Bojana, Hugli, Olivier, Jean-Scherb, Sandy, Rovati, Lucrezia, Kirsch, Monika, Sampson, Fiona C, Mayer, Gernot, Thomys, Heike, & Minotti, Bruno. (2025). Defining the need for analgesia in the emergency department: Protocol for an international Delphi process. BMJ Open, 15. https://doi.org/10.1136/bmjopen-2024-089396

Terhalle, L., Arntz, L., Hoffmann, F., Arnold, I., Hafner, L., Picking-Pitasch, L., Zuppinger, J., Delport Lehnen, K., Leuppi, J., Somasundaram, R., Nickel, C. H., & Bingisser, R. (2025). Nonspecific stress biomarkers for mortality prediction in older emergency department patients presenting with falls: a prospective multicenter observational study. Internal and Emergency Medicine, 20(2), 585–595. https://doi.org/10.1007/s11739-024-03693-6

Beil, Michael, Alberto, Laura, Bourne, Richard S., Brummel, Nathan E., de Groot, Bas, de Lange, Dylan W., Elbers, Paul, Emmelot-Vonk, Marielle, Flaatten, Hans, Freund, Yonathan, Galazzi, Alessandro, Garcia-Martinez, Ana, Guidet, Bertrand, Holmerova, Iva, Jacobs, Jeremy M., Joynt, Gavin M., Leaver, Susannah, Leone, Marc, McNicholas, Bairbre, et al. (2025). ESICM consensus-based recommendations for the management of very old patients in intensive care. Intensive Care Medicine, 51, 287–301. https://doi.org/10.1007/s00134-025-07794-4

Benhamou, Jonathan, Espejo, Tanguy, Riedel, Henk B., Dreher-Hummel, Thomas, García-Martínez, Ana, Gubler-Gut, Barbara, Kirchberger, Joris, Overberg, Jan-Arie, Perrot, Guido, Bingisser, Roland, & Nickel, Christian H. (2025). On-site physiotherapy in older emergency department patients following a fall: a randomized controlled trial [Journal-article]. European Geriatric Medicine, 16(1), 205–217. https://doi.org/10.1007/s41999-024-01091-x

Jonathan Benhamou 1 , Tanguy Espejo 1 , Henk B Riedel 1 , Thomas Dreher-Hummel 1 , Ana García-Martínez 2 , Barbara Gubler-Gut 3 , Joris Kirchberger 3 , Jan-Arie Overberg 3 , Guido Perrot 3 , Roland Bingisser 1 , Christian H Nickel 4. (2025). On-site physiotherapy in older emergency department patients following a fall: a randomized controlled trial [Journal-article]. European Geriatric Medicine, 16(1), 205–217. https://doi.org/10.1007/s41999-024-01091-x

Beil, Michael, Alberto, Laura, Bourne, Richard S., Brummel, Nathan E., de Groot, Bas, de Lange, Dylan W., Elbers, Paul, Emmelot-Vonk, Marielle, Flaatten, Hans, Freund, Yonathan, Galazzi, Alessandro, Garcia-Martinez, Ana, Guidet, Bertrand, Holmerova, Iva, Jacobs, Jeremy M., Joynt, Gavin M., Leaver, Susannah, Leone, Marc, McNicholas, Bairbre, et al. (2025). Correction to: ESICM consensus-based recommendations for the management of very old patients in intensive care (Intensive Care Medicine, (2025), 51, 2, (287-301), 10.1007/s00134-025-07794-4). Intensive Care Medicine. https://doi.org/10.1007/s00134-025-07881-6

Espejo, Tanguy, Nieves-Ortega, Ricardo, Amsler, Livia, Riedel, Henk Börje, Balestra, Gianmarco, Rosin, Christiane, Becker, Christoph, Lippay, Kriemhild, Nickel, Christian Hans, & Bingisser, Roland. (2025). Clinical Gestalt to Predict Bacterial Infection and Mortality in Emergency Department Patients: A Prospective Observational Study. Journal of General Internal Medicine. https://doi.org/10.1007/s11606-025-09440-7

Pfundstein, Isabel, Mauthner, Oliver, Gschwind, Cynthia O., Muser, Olga, Nickel, Christian H., Trutschel, Diana, & Brunkert, Thekla. (2025). A Multi-Method Study to Develop and Pilot Test an Interprofessional Transitional Care Model for Frail Older Adults – AdvantAGE. Journal of Advanced Nursing. https://doi.org/10.1111/jan.16822

Stephan, Frank-Peter, Riede, Florian N., Ünlü, Luca, Capoferri, Gioele, Bosia, Tito, Regeniter, Axel, Bingisser, Roland, & Nickel, Christian H. (2025). Hyperkalemia or Not? A Diagnostic Pitfall in the Emergency Department. Western Journal of Emergency Medicine, 26, 176–179. https://doi.org/10.5811/westjem.35286

Szczesna, A.Z., Nissen, S.K., Brabrand, M., Bingisser, R., & Nickel, C.H. (2025). Validation of the Frailty-Adjusted Prognosis Tool for 30-Day Mortality in Older Emergency Department Patients. International Journal of Clinical Practice, 2025. https://doi.org/10.1155/ijcp/2048711

van Oppen, James D, Mooijaart, Simon, Nickel, Christian H, & Conroy, Simon. (2025). Considering frailty and meaningful outcomes in geriatric emergency care. Internal and Emergency Medicine. https://doi.org/10.1007/s11739-025-03940-4

Fehlmann, C. A., Mc Loughlin, K., Cosgriff, E. J., Ferrick, J. F., van Oppen, J., Coats, T., Conroy, S., de Groot, B., Heeren, P., Lim, S., Lucke, J., Mooijaart, S., Nickel, C. H., Penfold, R., Singler, K., Heeren, P., Steenebruggen, F., Sterckx, V., Brdar, I., et al. (2024). Service provision for Frailty in European Emergency Departments (FEED): a survey of operational characteristics. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 32(1). https://doi.org/10.1186/s13049-024-01234-w

García-Martínez, A., García-Rosa, S., Gil-Rodrigo, A., Machado, V. T., Pérez-Fonseca, C., Nickel, C. H., Artajona, L., Jacob, J., Llorens, P., Herrero, P., Canadell, N., Rangel, C., Martín-Sánchez, F. J., del Nogal, M. L., & Miró, Ò. (2024). Prevalence and outcomes of fear of falling in older adults with falls at the emergency department: a multicentric observational study. European Geriatric Medicine, 15(5), 1281–1289. https://doi.org/10.1007/s41999-024-00992-1

Seidenfeld, J., Lee, S., Ragsdale, L., Nickel, C. H., Liu, S. W., & Kennedy, M. (2024). Risk factors and risk stratification approaches for delirium screening: A Geriatric Emergency Department Guidelines 2.0 systematic review. Academic Emergency Medicine, 31(10), 969–984. https://doi.org/10.1111/acem.14939

Espejo, T., Terhalle, L., Malinovska, A., Riedel, H. B., Arntz, L., Hafner, L., Delport-Lehnen, K., Zuppinger, J., Geigy, N., Leuppi, J., Somasundaram, R., Bingisser, R., & Nickel, C. H. (2024). Diagnostic and prognostic value of cardiac troponins in emergency department patients presenting after a fall: A prospective, multicenter study. Academic Emergency Medicine, 31(9), 860–869. https://doi.org/10.1111/acem.14897

Crisman, Elena, Appenzeller-Herzog, Christian, Tabakovic, Senad, Nickel, Christian Hans, & Minotti, Bruno. (2024). Multidimensional versus unidimensional pain scales for the assessment of analgesic requirement in the emergency department: a systematic review. Internal and Emergency Medicine, 19(5), 1463–1471. https://doi.org/10.1007/s11739-024-03608-5

Espejo, T., Wagner, N., Riedel, H. B., Karakoumis, J., Geigy, N., Nickel, C. H., & Bingisser, R. (2024). Prognostic value of cognitive impairment, assessed by the Clock Drawing Test, in emergency department patients presenting with non-specific complaints. European Journal of Internal Medicine, 126, 56–62. https://doi.org/10.1016/j.ejim.2024.03.016

Fumagalli, Riccardo M., Voci, Davide, Bikdeli, Behnood, Bingisser, Roland, Colucci, Giuseppe, Forgo, Gabor, Gerardi, Teresa, Gerber, Bernhard, Grigorean, Alexandru, Klok, Frederikus A., Righini, Marc, Robert-Ebadi, Helia, Stortecky, Stefan, Ulrich, Silvia, Wolf, Simon, Wyss, Dörte, Hobohm, Lukas, Kucher, Nils, Barco, Stefano, et al. (2024). Long-term course of ambulatory patients with COVID-19 initially treated with enoxaparin vs no anticoagulation: final analysis of the OVID (enoxaparin for outpatients with COVID-19) randomized trial. Research and Practice in Thrombosis and Haemostasis, 8. https://doi.org/10.1016/j.rpth.2024.102534

Chrobok, Leon, Espejo, Tanguy, Riedel, Henk B., Kirchberger, Joris, Overberg, Jan-Arie, Felber, Florina, Perrot, Guido, Nickel, Christian H., & Bingisser, Roland. (2024). On-Site Physiotherapy in Emergency Department Patients Presenting with Nonspecific Low Back Pain: A Randomized Controlled Trial. Journal of Clinical Medicine, 13(11). https://doi.org/10.3390/jcm13113149

Mols, Elisabeth Margaretha, Haak, Harm, Holland, Mark, Schouten, Bo, Ibsen, Stine, Merten, Hanneke, Christensen, Erika Frischknecht, Nanayakkara, Prabath W.B., Nickel, Christian Hans, Weichert, Immo, Kellett, John, Subbe, Christian Peter, & Kremers, Marjolein N.T. (2024). Can acutely ill patients predict their outcomes? A scoping review. Emergency Medicine Journal, 41(6), 342–349. https://doi.org/10.1136/emermed-2022-213000

Riedel, H. B., Espejo, T., Dreher-Hummel, T., Bingisser, R., & Nickel, C. H. (2024). Screening for elder mistreatment in a Swiss emergency department: a prospective cohort study. Swiss Medical Weekly, 154(6). https://doi.org/10.57187/s.3775

Espejo, Tanguy, Riedel, Henk B., Messingschlager, Sebastian, Sonnleitner, Wolfram, Kellett, John, Brabrand, Mikkel, Cooksley, Tim, Bingisser, Roland, & Nickel, Christian H. (2024). Predictive value and interrater reliability of mental status and mobility assessment in the emergency department. Clinical Medicine, Journal of the Royal College of Physicians of London, 24(2). https://doi.org/10.1016/j.clinme.2024.100027

Albrecht, Rainer, Espejo, Tanguy, Riedel, Henk B., Nissen, Søren K., Banerjee, Jay, Conroy, Simon P., Dreher-Hummel, Thomas, Brabrand, Mikkel, Bingisser, Roland, & Nickel, Christian H. (2024). Clinical Frailty Scale at presentation to the emergency department: interrater reliability and use of algorithm-assisted assessment. European Geriatric Medicine, 15(1), 105–113. https://doi.org/10.1007/s41999-023-00890-y

Sojak, Lina, Toebak, Anna M., Gallino, Camilla, von Streng, Tennessee, Rudin, Salome, Kriemler, Lilian F., Zietz, Annaelle, Wagner, Benjamin, Gensicke, Henrik, Sutter, Raoul, Nickel, Christian H., Katan, Mira, Bonati, Leo H., Psychogios, Marios, Dittrich, Tolga D., & De Marchis, Gian Marco. (2024). Association between ischaemic stroke aetiology and leptomeningeal collateral status: a retrospective cohort study. Swiss Medical Weekly, 154(7). https://doi.org/10.57187/s.3584

Cuénod, Aline, Agnetti, Jessica, Seth-Smith, Helena M. B., Roloff, Tim, Wälchli, Denise, Shcherbakov, Dimitri, Akbergenov, Rashid, Tschudin-Sutter, Sarah, Bassetti, Stefano, Siegemund, Martin, Nickel, Christian H., Moran-Gilad, Jacob, Keys, Timothy G., Pflüger, Valentin, Thomson, Nicholas R., & Egli, Adrian. (2023). Bacterial genome-wide association study substantiates papGII of Escherichia coli as a major risk factor for urosepsis. Genome Medicine, 15(1). https://doi.org/10.1186/s13073-023-01243-x

Lo, Ronson Sze Long, Lyngholm, Le Elias, Brabrand, Mikkel, Leung, Ling Yan, Hung, Kevin Kei Ching, Laugesen, Sune, Posth, Stefan, Cooksley, Tim, Graham, Colin A, & Nickel, Christian H. (2023). A tale of two continents: The performance of six early warning scores in two emergency departments. Hong Kong Journal of Emergency Medicine, 30(6), 374–380. https://doi.org/10.1177/10249079231153719

Nickel, Christian H., & Kellett, John. (2023). Assessing Physiologic Reserve and Frailty in the Older Emergency Department Patient: Should the Paradigm Change? Clinics in Geriatric Medicine, 39(4), 475–489. https://doi.org/10.1016/j.cger.2023.05.004

Meier, Mario, Boeddinghaus, Jasper, Nestelberger, Thomas, Nestelberger, Thomas, Koechlin, Luca, Lopez-Ayala, Pedro, Wussler, Desiree, Walter, Joan Elias, Zimmermann, Tobias, Badertscher, Patrick, Wildi, Karin, Gimenez, Maria Rubini, Puelacher, Christian, Glarner, Noemi, Magni, Jan, Miró, Òscar, Martin-Sanchez, Francisco Javier, Kawecki, Damian, Keller, Dagmar I, et al. (2023). Comparing the utility of clinical risk scores and integrated clinical judgement in patients with suspected acute coronary syndrome. European Heart Journal: Acute Cardiovascular Care, 12(10), 693–702. https://doi.org/10.1093/ehjacc/zuad081

Miró, Òscar, Gil-Rodrigo, Adriana, García-Martínez, Ana, Aguiló, Sira, Alemany, Xavier, Nickel, Christian H., Jacob, Javier, Llorens, Pere, Herrero, Pablo, Torres-Machado, Victoria, Cenjor, Raquel, Coll-Vinent, Blanca, Martínez-Nadal, Gemma, del Nogal, Montserrat Lázaro, Peacock, Frank, & Martín-Sánchez, Francisco Javier. (2023). Sex differences in mortality of older adults with falls after emergency department consultation: FALL-ER registry. Journal of the American Geriatrics Society, 71(9), 2715–2725. https://doi.org/10.1111/jgs.18401

Polymeris, Alexandros A., Karwacki, Grzegorz M., Siepen, Bernhard M., Schaedelin, Sabine, Tsakiris, Dimitrios A., Stippich, Christoph, Guzman, Raphael, Nickel, Christian H., Sprigg, Nikola, Kägi, Georg, Vehoff, Jochen, Barinka, Filip, Thilemann, Sebastian, Maurer, Marina, Wagner, Benjamin, Traenka, Christopher, Gensicke, Henrik, De Marchis, Gian Marco, Bonati, Leo H., et al. (2023). Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist Oral Anticoagulants (TICH-NOAC): A Multicenter, Randomized, Placebo-Controlled, Phase 2 Trial. Stroke, 54(9), 2223–2234. https://doi.org/10.1161/STROKEAHA.123.042866

Riedel HB, Espejo T, Bingisser R, Kellett J, & Nickel CH. (2023). A fast emergency department triage score based on mobility, mental status and oxygen saturation compared with the emergency severity index: a prospective cohort study. QJM: An International Journal of Medicine , 116(9), 774–780. https://doi.org/10.1093/qjmed/hcad160

Candel BGJ, Nissen SK, Nickel CH, Raven W, Thijssen W, Gaakeer MI, Lassen AT, Brabrand M, Steyerberg EW, de Jonge E, & de Groot B. (2023). Development and External Validation of the International Early Warning Score for Improved Age- and Sex-Adjusted In-Hospital Mortality Prediction in the Emergency Department. Critical Care Medicine, 51(7), 881–891. https://doi.org/10.1097/CCM.0000000000005842

Dittrich, Tolga D, Sporns, Peter B, Kriemler, Lilian F, Rudin, Salome, Nguyen, Anh, Zietz, Annaelle, Polymeris, Alexandros A, Tränka, Christopher, Thilemann, Sebastian, Wagner, Benjamin, Altersberger, Valerian L, Piot, Ines, Barinka, Filip, Hänsel, Martin, Gensicke, Henrik, Engelter, Stefan T, Lyrer, Philippe A, Sutter, Raoul, Nickel, Christian H, et al. (2023). Mechanical thrombectomy for large vessel occlusion between 6 and 24 h: outcome comparison of DEFUSE-3/DAWN eligible versus non-eligible patients. International Journal of Stroke, 18(6), 697–703. https://doi.org/10.1177/17474930221140793

Dittrich, Tolga D, Aujesky, Mara, Rudin, Salome, Zietz, Annaelle, Wagner, Benjamin, Polymeris, Alexandros, Altersberger, Valerian L, Sinnecker, Tim, Gensicke, Henrik, Engelter, Stefan T, Lyrer, Philippe, Hess, Viviane, Sutter, Raoul, Nickel, Christian H, Bonati, Leo H, Fischer, Urs, Psychogios, Marios, Katan, Mira, & De Marchis, Gian Marco. (2023). Apical pulmonary lesions suspected of malignancy visible on neck CT angiography performed for acute stroke: Prevalence, treatment, and clinical implications – the PLEURA study. European Stroke Journal, 8(2), 549–556. https://doi.org/10.1177/23969873231151488

Boeddinghaus Jasper, Boeddinghaus, Jasper, Nestelberger, Thomas, Koechlin, Luca, Lopez-Ayala, Pedro, Wussler, Desiree, Mais, Maximilian, Zwimpfer, Luca, Zimmermann, Tobias, Wildi, Karin, Giménez, Maria Rubini, Strebel, Ivo, Miró, Òscar, Martin-Sanchez, F. Javier, Parenica, Jiri, Keller, Dagmar I., Gualandro, Danielle M., Nickel, Christian H., Bingisser, Roland, et al. (2023). Association of accompanying dyspnoea with diagnosis and outcome of patients presenting with acute chest discomfort. European Heart Journal: Acute Cardiovascular Care, 12(5), 283–295. https://doi.org/10.1093/ehjacc/zuad026

Kabell Nissen S, Rueegg M, Carpenter CR, Kaeppeli T, Busch JM, Fournaise A, Dreher-Hummel T, Bingisser R, Brabrand M, & Nickel CH. (2023). Prognosis for older people at presentation to emergency department based on frailty and aggregated vital signs. Journal of the American Geriatrics Society, 71(4), 1250–1258. https://doi.org/10.1111/jgs.18170

Dittrich, Tolga D., Sporns, Peter B., Kriemler, Lilian F., Rudin, Salome, Nguyen, Anh, Zietz, Annaelle, Polymeris, Alexandros A., Tränka, Christopher, Thilemann, Sebastian, Wagner, Benjamin, Altersberger, Valerian L., Piot, Ines, Barinka, Filip, Müller, Susanne, Hänsel, Martin, Gensicke, Henrik, Engelter, Stefan T., Lyrer, Philippe A., Sutter, Raoul, et al. (2023). Mechanical Thrombectomy Versus Best Medical Treatment in the Late Time Window in Non-DEFUSE-Non-DAWN Patients: A Multicenter Cohort Study. Stroke, 54(3), 722–730. https://doi.org/10.1161/strokeaha.122.039793

Arnold, Isabelle, Busch, Jeannette-Marie, Terhalle, Lukas, Nickel, Christian H., & Bingisser, Roland. (2023). Throughput delays: causes, predictors, and outcomes – observational cohort in a Swiss emergency department. Swiss Medical Weekly, 153(5). https://doi.org/10.57187/smw.2023.40084

Busch, Jeannette-Marie, Arnold, Isabelle, Karakoumis, Julia, Winkel, David J., Segeroth, Martin, Nickel, Christian H., & Bingisser, Roland. (2023). Emergency Presentations for Dizziness - Radiological Findings, Final Diagnoses, and Mortality. International Journal of Clinical Practice, 2023. https://doi.org/10.1155/2023/7450009

Klasen, Jennifer M., Poljo, Adisa, Sortino, Rosita, Bogie, Bryce J. M., Schoenbaechler, Zoe, Meienberg, Andrea, Nickel, Christian, Bingisser, Roland, & LaDonna, Kori A. (2023). Medical students on the COVID-19 frontline: a qualitative investigation of experiences of relief, stress, and mental health. Frontiers in Medicine, 10. https://doi.org/10.3389/fmed.2023.1249618

Thilemann, Sebastian, Traenka, Christoph Kenan, Schaub, Fabian, Nussbaum, Lukas, Bonati, Leo, Peters, Nils, Fladt, Joachim, Nickel, Christian, Hunziker, Patrick, Luethy, Marc, Schädelin, Sabine, Ernst, Axel, Engelter, Stefan, De Marchis, Gian Marco, & Lyrer, Philippe. (2023). Real-time video analysis allows the identification of large vessel occlusion in patients with suspected stroke: feasibility trial of a “telestroke” pathway in Northwestern Switzerland. Frontiers in Neurology, 14. https://doi.org/10.3389/fneur.2023.1232401

Ibsen S, Dam-Huus KB, Nickel CH, Christensen EF, & Søvsø MB. (2022). Diagnoses and mortality among prehospital emergency patients calling 112 with unclear problems: a population-based cohort study from Denmark. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 30(1), 70. https://doi.org/10.1186/s13049-022-01052-y

Fehlmann CA, Nickel CH, Cino E, Al-Najjar Z, Langlois N, & Eagles D. (2022). Frailty assessment in emergency medicine using the Clinical Frailty Scale: a scoping review. Internal and Emergency Medicine, 17(8), 2407–2418. https://doi.org/10.1007/s11739-022-03042-5

Simon NR, Jauslin AS, Bingisser R, & Nickel CH. (2022). Emergency presentations of older patients living with frailty: Presenting symptoms compared with non-frail patients. American Journal of Emergency Medicine, 59, 111–117. https://doi.org/10.1016/j.ajem.2022.06.046

Minotti, Bruno, Mansella, Gregory, Sieber, Robert, Ott, Alexander, Nickel, Christian H., & Bingisser, Roland. (2022). Intravenous acetaminophen does not reduce morphine use for pain relief in emergency department patients: A multicenter, randomized, double-blind, placebo-controlled trial. Academic Emergency Medicine, 29(8), 954–962. https://doi.org/10.1111/acem.14517

Kellett J, Holland M, Alsma J, Nickel CH, Brabrand M, & Lumala A. (2022). Are changes in vital signs, mobility, and mental status while in hospital measures of the quality of care? Clinical Medicine, Journal of the Royal College of Physicians of London, 22(4), 4–320. https://doi.org/10.7861/clinmed.2021-0712

Schweizer, Lisa, Sieber, Robert, Nickel, Christian H., & Minotti, Bruno. (2022). Ability of pain scoring scales to differentiate between patients desiring analgesia and those who do not in the emergency department. American Journal of Emergency Medicine, 57, 107–113. https://doi.org/10.1016/j.ajem.2022.04.046

Rueegg M, Nissen SK, Brabrand M, Kaeppeli T, Dreher T, Carpenter CR, Bingisser R, & Nickel CH. (2022). The clinical frailty scale predicts 1-year mortality in emergency department patients aged 65 years and older. Academic Emergency Medicine, 29(5), 572–580. https://doi.org/10.1111/acem.14460

Lucke JA, Mooijaart SP, Conroy S, Blomaard LC, De Groot B, & Nickel CH. (2022). Mortality risk for different presenting complaints amongst older patients assessed with the Manchester triage system. European Geriatric Medicine, 13(2), 323–328. https://doi.org/10.1007/s41999-021-00568-3

Lucke JA, Mooijaart SP, Heeren P, Singler K, McNamara R, Gilbert T, Nickel CH, Castejon S, Mitchell A, Mezera V, Van der Linden L, Lim SE, Thaur A, Karamercan MA, Blomaard LC, Dundar ZD, Chueng KY, Islam F, de Groot B, & Conroy S. (2022). Providing care for older adults in the Emergency Department: expert clinical recommendations from the European Task Force on Geriatric Emergency Medicine. European Geriatric Medicine, 13(2), 309–317. https://doi.org/10.1007/s41999-021-00578-1

Nickel CH, & Nissen SK. (2022). Still under our radar: Elder mistreatment. European Journal of Emergency Medicine, 29(2), 97–98. https://doi.org/10.1097/MEJ.0000000000000911

Nissen SK, Candel BGJ, Nickel CH, de Jonge E, Ryg J, Bogh SB, de Groot B, & Brabrand M. (2022). The Impact of Age on Predictive Performance of National Early Warning Score at Arrival to Emergency Departments: Development and External Validation. Annals of Emergency Medicine, 79(4), 354–363. https://doi.org/10.1016/j.annemergmed.2021.09.434

de Groot B, Jessen MK, & Nickel CH. (2022). The new 2021 Surviving Sepsis Guidelines: an emergency department perspective may be more effective. European Journal of Emergency Medicine, 29(1), 5–6. https://doi.org/10.1097/MEJ.0000000000000898

Niedermeier S, Wania R, Lampart A, Stahl R, Trumm C, Kammerlander C, Böcker W, Nickel CH, Bingisser R, Armbruster M, & Pedersen V. (2022). Incidental CT Findings in the Elderly with Low-Energy Falls: Prevalence and Implications. Diagnostics, 12(2). https://doi.org/10.3390/diagnostics12020354

Raven W, van den Hoven EMP, Gaakeer MI, Ter Avest E, Sir O, Lameijer H, Hessels RAPA, Reijnen R, van Zwet E, de Jonge E, Nickel CH, & de Groot B. (2022). The association between presenting complaints and clinical outcomes in emergency department patients of different age categories. European Journal of Emergency Medicine, 29(1), 33–41. https://doi.org/10.1097/MEJ.0000000000000860

Busch JM, Arnold I, Kellett J, Brabrand M, Bingisser R, & Nickel CH. (2022). Validation of a Simple Score for Mortality Prediction in a Cohort of Unselected Emergency Patients. International Journal of Clinical Practice, 2022, 7281693. https://doi.org/10.1155/2022/7281693

Guerbaai, Raphaëlle A., Kressig, Reto W., Zeller, Andreas, Tröger, Monika, Nickel, Christian H., Benkert, Brigitte, Wellens, Nathalie I. H., Osińska, Magdalena, Simon, Michael, Zúñiga, Franziska, & Intercare Research Group,. (2022). Identifying Appropriate Nursing Home Resources to Reduce Fall-Related Emergency Department Transfers. Journal of the American Medical Directors Association, 23(8), 1304–1310. https://doi.org/10.1016/j.jamda.2022.01.063

Kellett J, Sikakulya FK, & Nickel CH. (2022). The prediction of early mortality by the ROX index of oxygenation and respiratory rate in diverse Canadian and Ugandan cohorts of unselected patient: a post-hoc retrospective analysis of 80,558 patient observations. Acute Medicine, 21(2), 68–73. https://doi.org/10.52964/AMJA.0900

Kennedy A, Holland M, Sullivan P, Gebril A, Arora N, Vijayakumar V, Hoole A, Nickel C, Hodcroft C, Harrington L, Wheble M, Soong J, Scriven N, Kellett J, Slinger K, Price V, Alsma J, Astbury S, Varia R, et al. (2022). Developing priorities for quality improvement in acute medicine using a modified Delphi method A consensus process hosted by the Society for Acute Medicine Quality Improvement Committee (SAM-QI). Acute Medicine, 21(2), 74–79. https://doi.org/10.52964/AMJA.0901

Klasen JM, Schoenbaechler Z, Bogie BJM, Meienberg A, Nickel C, Bingisser R, & LaDonna K. (2022). Medical students’ perceptions of learning and working on the COVID-19 frontlines: ‘… a confirmation that I am in the right place professionally’. Medical Education Online, 27(1), 2082265. https://doi.org/10.1080/10872981.2022.2082265

Malinovska A, Malinovska L, Nickel CH, & Bingisser R. (2022). Prevalence and prognosis of fever symptoms, hypo-, and hyperthermia in unselected emergency patients. Journal of Clinical Medicine, 11(1). https://doi.org/10.3390/jcm11010024

Shrestha, Samyut, Lopez-Ayala, Pedro, Schaefer, Ibrahim, Nardiello, Svetlana S., Papachristou, Androniki, Aliyeva, Fatima, Simmen, Cornelia, Wussler, Desiree, Belkin, Maria, Gualandro, Danielle M., Puelacher, Christian, Michou, Eleni, Pfister, Otmar, Bingisser, Roland, Nickel, Christian H., Breidthardt, Tobias, & Mueller, Christian. (2022). Efficacy and safety of digoxin in acute heart failure triggered by tachyarrhythmia. Journal of Internal Medicine, 292(6), 969–972. https://doi.org/10.1111/joim.13565

Jauslin AS, Simon NR, Giudici NL, Rueegg M, Zimmermann T, Diebold M, Tschudin-Sutter S, Twerenbold R, Nickel CH, & Bingisser R. (2021). Mimics and chameleons of COVID-19: patient presentation and accuracy of triage during the first wave. Swiss Medical Weekly, 151(49-50), w30103. https://doi.org/10.4414/smw.2021.w30103

Caspar M., Dutilh G., Achermann S., Bingisser R., & Nickel CH. (2021). Contact-Free Monitoring of Pulse Rate For Triage of Patients Presenting to the Emergency Department. Journal of Emergency Medicine, 61(6), 649–657. https://doi.org/10.1016/j.jemermed.2021.07.005

Fournaise A, Nissen SK, Lauridsen JT, Ryg J, Nickel CH, Gudex C, Brabrand M, Poulsen LM, & Andersen-Ranberg K. (2021). Translation of the updated clinical frailty scale 2.0 into Danish and implications for cross-sectoral reliability (Patent No. 1). BMC Geriatrics, 21(1), Article 1. https://doi.org/10.1186/s12877-021-02222-w

Ibsen S, Lindskou TA, Nickel CH, Kløjgård T, Christensen EF, & Søvsø MB. (2021). Which symptoms pose the highest risk in patients calling for an ambulance? A population-based cohort study from Denmark. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 29(1), 59. https://doi.org/10.1186/s13049-021-00874-6

Leuzinger, Karoline, Osthoff, Michael, Dräger, Sarah, Pargger, Hans, Siegemund, Martin, Bassetti, Stefano, Bingisser, Roland, Nickel, Christian H., Tschudin-Sutter, Sarah, Khanna, Nina, Rentsch, Katharina, Battegay, Manuel, Egli, Adrian, & Hirsch, Hans H. (2021). Comparing immunoassays for sars-cov-2 antibody detection in patients with and without laboratory-confirmed sars-cov-2 infection. Journal of Clinical Microbiology, 59(12), e0138121. https://doi.org/10.1128/JCM.01381-21

Nieves-Ortega R, Brabrand M, Dutilh G, Kellett J, Bingisser R, & Nickel CH. (2021). Assessment of patient mobility improves the risk stratification of triage with the Emergency Severity Index: A prospective cohort study. European Journal of Emergency Medicine, 28(6), 456–462. https://doi.org/10.1097/MEJ.0000000000000845

Søgaard KK, Baettig V, Osthoff M, Marsch S, Leuzinger K, Schweitzer M, Meier J, Bassetti S, Bingisser R, Nickel CH, Khanna N, Tschudin-Sutter S, Weisser M, Battegay M, Hirsch HH, Pargger H, Siegemund M, & Egli A. (2021). Community-acquired and hospital-acquired respiratory tract infection and bloodstream infection in patients hospitalized with COVID-19 pneumonia. Journal of Intensive Care, 9(1), 10. https://doi.org/10.1186/s40560-021-00526-y

van den Ende ES, Schouten B, Kremers MNT, Cooksley T, Subbe CP, Weichert I, van Galen LS, Haak HR, Kellett J, Alsma J, Siegrist V, Holland M, Christensen EF, Graham CA, Leung LY, Laugesen LE, Merten H, Mir F, Kidney RM, et al. (2021). Understanding what matters most to patients in acute care in seven countries, using the flash mob study design. BMC Health Services Research, 21(1), 474. https://doi.org/10.1186/s12913-021-06459-4

Jauslin AS, Schultze L, Knuchel D, Simon NR, Nickel CH, & Bingisser R. (2021). Disparities in emergency department access, resource allocation, and outcomes between migrants and the local population. Swiss Medical Weekly, 151(43-44), w30070. https://doi.org/10.4414/smw.2021.w30070

Bingisser R., Simon N.R., & Nickel CH. (2021). Comment to: Non-specific clinical presentations are not prognostic and do not anticipate hospital length of stay or resource utilization. European Journal of Internal Medicine, 91, 85–86. https://doi.org/10.1016/j.ejim.2021.06.011

Brabrand M, Kellett J, & Nickel CH. (2021). The Reply (Patent No. 8). American Journal of Medicine, 134(8), Article 8. https://doi.org/10.1016/j.amjmed.2021.03.019

De Hond A, Raven W, Schinkelshoek L, Gaakeer M, Ter Avest E, Sir O, Lameijer H, Hessels RA, Reijnen R, De Jonge E, Steyerberg E, Nickel CH, & De Groot B. (2021). Machine learning for developing a prediction model of hospital admission of emergency department patients: Hype or hope? International Journal of Medical Informatics, 152, 104496. https://doi.org/10.1016/j.ijmedinf.2021.104496

Möckel M, Nickel CH, Behringer W, & Backus B. (2021). Status of physician education in emergency medicine in four European countries: No primary specialty yet. European Journal of Emergency Medicine, 28(4), 257–259. https://doi.org/10.1097/MEJ.0000000000000837

Schmuelling L, Franzeck F.C., Nickel CH, Mansella G., Bingisser R., Schmidt N, Stieltjes B., Bremerich J, Sauter AW, Weikert T., & Sommer G. (2021). Deep learning-based automated detection of pulmonary embolism on CT pulmonary angiograms: No significant effects on report communication times and patient turnaround in the emergency department nine months after technical implementation. European Journal of Radiology, 141, 109816. https://doi.org/10.1016/j.ejrad.2021.109816

Patzen, Annalea, Simon, Noemi R., Jauslin, Andrea S., Nickel, Christian H., & Bingisser, Roland. (2021). Nonspecific complaints in emergency medicine: Contribution of clinical chemistry and diagnostic imaging to final diagnosis. an observational study. Signa Vitae, 17, 49–54. https://doi.org/10.22514/sv.2021.096

Tsagkas C, Schäfer S, Baumgartner A, Müller J, Sinnecker T, Mehling M, van der Stouwe JG, Felder S, Panagiotou A, Potlukova E, Winzeler B, Scholz MC, Timper K, Blackham K, Nickel CH, Christ-Crain M, Bingisser R, Lyrer P, Kappos L, & Yaldizli Ö. (2021). Syndrome of inappropriate antidiuretic hormone secretion and hypothalamic hypocortisolism in neuromyelitis optica. The Lancet, 397(10290), 2194. https://doi.org/10.1016/S0140-6736(21)00986-7

Lampart M, Rüegg M, Jauslin AS, Simon NR, Zellweger N, Eken C, Tschudin-Sutter S, Bassetti S, Rentsch KM, Siegemund M, Bingisser R, Nickel CH, Osswald S, Kuster GM, & Twerenbold R. (2021). Direct comparison of clinical characteristics, outcomes and risk prediction in patients with covid-19 and controls—a prospective cohort study. Journal of Clinical Medicine, 10(12). https://doi.org/10.3390/jcm10122672

Brabrand M, Bogh SB, Fløjstrup M, Kellett J, Cooksley T, & Nickel CH. (2021). Routine measurement of d-dimers on suspected SARS-CoV2-infected patients does not lead to significant increase in radiological investigations (Patent No. 4). Internal and Emergency Medicine, 16(4), Article 4. https://doi.org/10.1007/s11739-020-02568-w

Lumala A, Kellett J, Alsma J, & Nickel CH. (2021). Is the “beach position” of value during the “eyeball” assessment of patients? [Elsevier B.V.]. European Journal of Internal Medicine, 88, 139–140. https://doi.org/10.1016/j.ejim.2021.02.014

Simon NR, Jauslin AS, Rueegg M, Twerenbold R, Lampart M, Osswald S, Bassetti S, Tschudin-Sutter S, Siegemund M, Nickel CH, & Bingisser R. (2021). Association of frailty with adverse outcomes in patients with suspected covid‐19 infection. Journal of Clinical Medicine, 10(11). https://doi.org/10.3390/jcm10112472

Rueegg M., Nickel CH, & Bingisser R. (2021). Disagreements between emergency patients and physicians regarding chief complaint – Patient factors and prognostic implications. International Journal of Clinical Practice, 75(5). https://doi.org/10.1111/ijcp.14070

Leuzinger K, Gosert R, Søgaard KK, Naegele K, Bielicki J, Roloff T, Bingisser R, Nickel CH, Khanna N, Sutter ST, Widmer AF, Rentsch K, Pargger H, Siegemund M, Stolz D, Tamm M, Bassetti S, Osthoff M, Battegay M, et al. (2021). Epidemiology and precision of SARS-CoV-2 detection following lockdown and relaxation measures. Journal of Medical Virology, 93(4), 2374–2384. https://doi.org/10.1002/jmv.26731

Mooijaart SP, Nickel CH, Conroy SP, Lucke JA, van Tol LS, Olthof M, Blomaard LC, Buurman BM, Dundar ZD, de Groot B, Gasperini B, Heeren P, Karamercan MA, McNamara R, Mitchell A, van Oppen JD, Martin Sanchez FJ, Schoon Y, Singler K, et al. (2021). A European Research Agenda for Geriatric Emergency Medicine: a modified Delphi study. European Geriatric Medicine, 12(2), 413–422. https://doi.org/10.1007/s41999-020-00426-8

Mueller O.S., Rentsch KM, Nickel CH, & Bingisser R. (2021). Disposition decision support by laboratory based outcome prediction. Journal of Clinical Medicine, 10(5), 1–15. https://doi.org/10.3390/jcm10050939

Leuzinger K, Roloff T, Gosert R, Sogaard K, Naegele K, Rentsch K, Bingisser R, Nickel CH, Pargger H, Bassetti S, Bielicki J, Khanna N, Tschudin Sutter S, Widmer A, Hinic V, Battegay M, Egli A, & Hirsch HH. (2021). Corrigendum to: Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2 Emergence Amidst Community-Acquired Respiratory Viruses. The Journal of Infectious Diseases, 223(4), 734–735. https://doi.org/10.1093/infdis/jiaa667

Nickel CH, Kellett J, Cooksley T, Lyngholm LE, Chang S, Imfeld S, Imfeld S, Bingisser R, & Brabrand M. (2021). The Diagnoses and Outcomes of Emergency Patients With an Elevated D-Dimer Over the Next 90 Days. American Journal of Medicine, 134(2), 260–266. https://doi.org/10.1016/j.amjmed.2020.06.009