D.D.S, PhD Karol Apaza Alccayhuaman

Guerra Cobian, Orlando, Mainetti, Giacomo, Bengazi, Franco, Mainetti, Tomaso, Apaza Alccayhuaman, Karol Alí, Nonaka, Mie, & Botticelli, Daniele. (2026). Guided Alveolar Ridge Preservation (G-ARP) with a Subperiosteal Cortical Lamina: A Retrospective Observational Case Series. Dentistry Journal, 14(6). https://doi.org/10.3390/dj14060361

Apaza Alccayhuaman, Karol Ali, Heimel, Patrick, Lettner, Stefan, Miron, Richard J., Kampleitner, Carina, Panahipour, Layla, Kuchler, Ulrike, & Gruber, Reinhard. (2026). Plasma-Coated Collagen Membranes Gain Barrier Function Through Heat Treatment. Journal of Functional Biomaterials, 17(2). https://doi.org/10.3390/jfb17020095

Aellos, F., Chang, E., Jeong, E., Liu, B., Yuan, X., Nazari, R., Hermans, F., Torabi, M.M., Ochweri, P.C., Cuevas, P., Rao, S., Alccayhuaman, K.A. Apaza, Sandoval, A., Coyac, B.R., Lambrichts, I., & Helms, J.A. (2026). WNT Signaling Modifies Barrier Functions of Junctional and Pocket Epithelium. Journal of Dental Research. https://doi.org/10.1177/00220345261458716

Apaza Alccayhuaman, Karol Alí, Heimel, Patrick, Dobsak, Toni, Tangl, Stefan, Loo, Geert van, Bosshardt, Dieter D., & Gruber, Reinhard. (2026). Myeloid A20 Regulates Periodontal Tissue Integrity and Temporomandibular Joint Structure. Journal of Periodontal Research. https://doi.org/10.1111/jre.70119

Farshidfar, Nima, Apaza Alccayhuaman, Karol Alí, Estrin, Nathan E., Ahmad, Paras, Sculean, Anton, Zhang, Yufeng, & Miron, Richard J. (2025). Advantages of horizontal centrifugation of platelet-rich fibrin in regenerative medicine and dentistry. Periodontology 2000, 99(1), 216–267. https://doi.org/10.1111/prd.12625

Apaza Alccayhuaman, Karol Ali, Heimel, Patrick, Tangl, Stefan, Lettner, Stefan, Kampleitner, Carina, Panahipour, Layla, Kuchler, Ulrike, & Gruber, Reinhard. (2024). Human versus Rat PRF on Collagen Membranes: A Pilot Study of Mineralization in Rat Calvaria Defect Model. Bioengineering, 11(5). https://doi.org/10.3390/bioengineering11050414

Apaza Alccayhuaman, Karol Ali, Heimel, Patrick, Tangl, Stefan, Lettner, Stefan, Kampleitner, Carina, Panahipour, Layla, Kuchler, Ulrike, & Gruber, Reinhard. (2024). Active and Passive Mineralization of Bio-Gide® Membranes in Rat Calvaria Defects. Journal of Functional Biomaterials, 15(3). https://doi.org/10.3390/jfb15030054

Nakajima, Yasushi, Apaza Alccayhuaman, Karol Alí, Botticelli, Daniele, Lang, Niklaus Peter, De Rossi, Ermenegildo Federico, & Xavier, Samuel Porfirio. (2023). Mucosal adhesion phenomenon after maxillary sinus floor elevation: A preclinical study. Clinical Oral Implants Research, 34(9), 967–978. https://doi.org/10.1111/clr.14123

Apaza Alccayhuaman, Karol Alí, Heimel, Patrick, Lee, Jung Seok, Tangl, Stefan, Kuchler, Ulrike, Marchesan, Julie, Panahipour, Layla, Lettner, Stefan, Matalová, Eva, & Gruber, Reinhard. (2023). FasL is a catabolic factor in alveolar bone homeostasis. Journal of Clinical Periodontology, 50(3), 396–405. https://doi.org/10.1111/jcpe.13750

Shanbhag, Siddharth, Kampleitner, Carina, Al-Sharabi, Niyaz, Mohamed-Ahmed, Samih, Apaza Alccayhuaman, Karol Ali, Heimel, Patrick, Tangl, Stefan, Beinlich, Andreas, Rana, Neha, Sanz, Mariano, Kristoffersen, Einar K., Mustafa, Kamal, & Gruber, Reinhard. (2023). Functionalizing Collagen Membranes with MSC-Conditioned Media Promotes Guided Bone Regeneration in Rat Calvarial Defects. Cells, 12(5). https://doi.org/10.3390/cells12050767

Agabiti, Ivo, Apaza Alccayhuaman, Karol Alí, Nakajima, Yasushi, & Botticelli, Daniele. (2021). An enigmatic soft tissue creeping phenomenon: The spontaneous peri-implant mucosa margin and papilla growth. A retrospective clinical study. Clinical and Experimental Dental Research, 7(4), 474–483. https://doi.org/10.1002/cre2.380

Alccayhuaman, Karol Alí Apaza, Tangl, Stefan, Blouin, Stéphane, Hartmann, Markus A., Heimel, Patrick, Kuchler, Ulrike, Lee, Jung-Seok, & Gruber, Reinhard. (2021). Osteoconductive properties of a volume-stable collagen matrix in rat calvaria defects: A pilot study. Biomedicines, 9(7). https://doi.org/10.3390/biomedicines9070732

Apaza Alccayhuaman, Karol Alí, Heimel, Patrick, Lee, Jung-Seok, Tangl, Stefan, Strauss, Franz J., Stähli, Alexandra, Matalová, Eva, & Gruber, Reinhard. (2021). FasL Is Required for Osseous Healing in Extraction Sockets in Mice. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.678873

Nasirzade, Jila, Alccayhuaman, Karol Alí Apaza, Kargarpour, Zahra, Kuchler, Ulrike, Strauss, Franz Josef, Panahipour, Layla, Kampleitner, Carina, Heimel, Patrick, Schwarz, Frank, & Gruber, Reinhard. (2021). Acid dentin lysate failed to modulate bone formation in rat calvaria defects. Biology, 10(3), 1–10. https://doi.org/10.3390/biology10030196

Favero, Giovanni, Apaza Alccayhuaman, Karol Alí, Silva, Erick Ricardo, Bengazi, Franco, Urbizo, Joaquin, Kotsu, Mitsuo, & Botticelli, Daniele. (2020). Effect of lack of plaque control after the surgical treatment of peri-implantitis at surfaces with different characteristics: an experimental study in dogs. Oral and Maxillofacial Surgery, 24(4), 431–439. https://doi.org/10.1007/s10006-020-00870-7

Strauss, Franz Josef, Stähli, Alexandra, Kobatake, Reiko, Tangl, Stefan, Heimel, Patrick, Apaza Alccayhuaman, Karol Alí, Schosserer, Markus, Hackl, Matthias, Grillari, Johannes, & Gruber, Reinhard. (2020). miRNA-21 deficiency impairs alveolar socket healing in mice. Journal of Periodontology, 91(12), 1664–1672. https://doi.org/10.1002/jper.19-0567

Masuda, Katsuhiko, Silv, Erick Ricardo, Alccayhuaman, Karol All Apaza, Botticelli, Daniele, & Xavier, Samuel Porfirio. (2020). Histologic and micro-CT analyses at implants placed immediately after maxillary sinus elevation using large or small xenograft granules: An experimental study in rabbits. International Journal of Oral and Maxillofacial Implants, 35(4), 739–748. https://doi.org/10.11607/jomi.8067

Tanaka, Kazushige, Iezzi, Giovanna, Piattelli, Adriano, Ferri, Mauro, Mesa, Natalia Fortich, Apaza Alccayhuaman, Karol Alí, & Botticelli, Daniele. (2019). Sinus Floor Elevation and Antrostomy Healing: A Histomorphometric Clinical Study in Humans. Implant Dentistry, 28(6), 537–542. https://doi.org/10.1097/id.0000000000000932

Viganò, Paolo, Apaza Alccayhuaman, Karol A., Sakuma, Shigeru, Amari, Yoshiyuki, Bengazi, Franco, & Botticelli, Daniele. (2019). Use of TiBrush for surface decontamination at peri-implantitis sites in dogs: Radiographic and histological outcomes. Journal of Investigative and Clinical Dentistry, 10(1), e12378. https://doi.org/10.1111/jicd.12378

Kawakami, Shunsuke, Lang, Niklaus P., Ferri, Mauro, Apaza Alccayhuaman, Karol Alí, & Botticelli, Daniele. (2019). Influence of the height of the antrostomy in sinus floor elevation assessed by cone beam computed tomography: A randomized clinical trial. International Journal of Oral and Maxillofacial Implants, 34(1), 223–232. https://doi.org/10.11607/jomi.7112

Masuda, Katsuhiko, Silva, Erick Ricardo, Botticelli, Daniele, Alccayhuaman, Karol Alí Apaza, & Xavier, Samuel P. (2019). Antrostomy preparation for maxillary sinus floor augmentation using drills or a sonic instrument: A microcomputed tomography and histomorphometric study in rabbits. International Journal of Oral and Maxillofacial Implants, 34(4), 819–827. https://doi.org/10.11607/jomi.7350

Iida, Takahisa, Silva, Erick Ricardo, Lang, Niklaus P., Apaza Alccayhuaman, Karol Alí, Botticelli, Daniele, & Xavier, Samuel P. (2018). Histological and micro-computed tomography evaluations of newly formed bone after maxillary sinus augmentation using a xenograft with similar density and mineral content of bone: An experimental study in rabbits. Clinical and Experimental Dental Research, 4(6), 284–290. https://doi.org/10.1002/cre2.146

Kawakami, Shunsuke, Lang, Niklaus P., Iida, Takahisa, Ferri, Mauro, Apaza Alccayhuaman, Karol A., & Botticelli, Daniele. (2018). Influence of the position of the antrostomy in sinus floor elevation assessed with cone-beam computed tomography: A randomized clinical trial. Journal of Investigative and Clinical Dentistry, 9(4), e12362. https://doi.org/10.1111/jicd.12362

Apaza Alccayhuaman, Karol Alí, Soto-Peñaloza, David, Nakajima, Yasushi, Papageorgiou, Spyridon N., Botticelli, Daniele, & Lang, Niklaus P. (2018). Biological and technical complications of tilted implants in comparison with straight implants supporting fixed dental prostheses. A systematic review and meta-analysis. Clinical Oral Implants Research, 29, 295–308. https://doi.org/10.1111/clr.13279

Hämmerle, Christoph H. F., Cordaro, Luca, Alccayhuaman, Karol A. Apaza, Botticelli, Daniele, Esposito, Marco, Colomina, Lino E., Gil, Alfonso, Gulje, Felix L., Ioannidis, Alexis, Meijer, Henny, Papageorgiou, Spyridon, Raghoebar, Gerry, Romeo, Eugenio, Renouard, Franck, Storelli, Stefano, Torsello, Ferruccio, & Wachtel, Hannes. (2018). Biomechanical aspects: Summary and consensus statements of group 4. The 5 th EAO Consensus Conference 2018. Clinical Oral Implants Research, 29, 326–331. https://doi.org/10.1111/clr.13284

Favero, Vittorio, Sakuma, Shigeru, Alccayhuaman, Karol Alí Apaza, Benedetto, Guillermo Alejandro, Bengazi, Franco, & Botticelli, Daniele. (2018). Healing at sites prepared using different drilling protocols. An experimental study in the tibiae of sheep. Plos One, 13(8). https://doi.org/10.1371/journal.pone.0202957

Omori, Yuki, Ricardo Silva, Erick, Botticelli, Daniele, Apaza Alccayhuaman, Karol Alí, Lang, Niklaus P., & Xavier, Samuel P. (2018). Reposition of the bone plate over the antrostomy in maxillary sinus augmentation: A histomorphometric study in rabbits. Clinical Oral Implants Research, 29(8), 821–834. https://doi.org/10.1111/clr.13292

Canullo, Luigi, Tallarico, Marco, Botticelli, Daniele, Alccayhuaman, Karol Alí Apaza, Martins Neto, Evandro Carneiro, & Xavier, Samuel Porfirio. (2018). Hard and soft tissue changes around implants activated using plasma of argon: A histomorphometric study in dog. Clinical Oral Implants Research, 29(4), 389–395. https://doi.org/10.1111/clr.13134

Cesaretti, G., Lang, N.P., Viganò, P., Bengazi, F., Apaza Alccayhuaman, K.A., & Botticelli, D. (2018). Immediate and delayed loading of fixed dental prostheses supported by single or two splinted implants: A histomorphometric study in dogs. Journal of Oral Rehabilitation, 45(4), 308–316. https://doi.org/10.1111/joor.12612

Iida, Takahisa, Carneiro Martins Neto, Evandro, Botticelli, Daniele, Apaza Alccayhuaman, Karol Alí, Lang, Niklaus P., & Xavier, Samuel P. (2017). Influence of a collagen membrane positioned subjacent the sinus mucosa following the elevation of the maxillary sinus. A histomorphometric study in rabbits. Clinical Oral Implants Research, 28(12), 1567–1576. https://doi.org/10.1111/clr.13027

Faggion, Clovis Mariano, Apaza, Karol, Ariza-Fritas, Tania, Malaga, Lilian, Giannakopoulos, Nikolaos Nikitas, & Alarcón, Marco Antonio. (2017). Methodological quality of consensus guidelines in implant dentistry. Plos One, 12(1). https://doi.org/10.1371/journal.pone.0170262

Alccayhuaman, Karol Ali Apaza, Zandinejad, Amirali, Beltrao, Rodrigo, Schick, Fabian, & Rohr, Nadja. (2026). ZrO Summit 2025, Group 4: Biological Complications and Peri-implant Tissue Response of Zirconia Compared with Titanium Dental Implants: A Systematic Review and Meta-analysis of Clinical Evidence [Journal-article]. International Journal of Oral and Maxillofacial Implants, 1–36. https://doi.org/10.11607/jomi.11786

López, Simón Pardiñas, Khouly, Ismael, Aellos, Fabiana, Alccayhuaman, Karol Apaza, & Díaz-Prado, Silvia. (2025). Clinical Efficacy and Patient-Reported Outcomes of Coconut Oil as Adjunctive Periodontitis Treatment: Triple-Blinded Randomized Trial [Posted-content]. In Clinical Efficacy and Patient-Reported Outcomes of Coconut Oil as Adjunctive Periodontitis Treatment: Triple-Blinded Randomized Trial. Springer Science and Business Media LLC. https://doi.org/10.21203/rs.3.rs-6038491/v1

Yonezawa, Daichi, Alccayhuaman, Karol Alí Apaza, Iezzi, Giovanna, Piattelli, Adriano, Ferri, Mauro, & Botticelli, Daniele. (2024). The Influence on Osseointegration of Immediate Functional Loading on Single Crowns: A Randomized, Double-Blind, Split-Mouth Controlled Clinical Trial with Histomorphometric Evaluation. International Journal of Oral and Maxillofacial Implants, 39(5), 669–706. https://doi.org/10.11607/jomi.10759

Feher, Balazs, Apaza Alccayhuaman, Karol Ali, Strauss, Franz Josef, Lee, Jung-Seok, Tangl, Stefan, Kuchler, Ulrike, & Gruber, Reinhard. (2021). Osteoconductive properties of upside-down bilayer collagen membranes in rat calvarial defects [Journal-article]. International Journal of Implant Dentistry, 7(1). https://doi.org/10.1186/s40729-021-00333-y

Amari, Yoshiyuki, Piattelli, Adriano, Apaza Alccayhuaman, Karol Alí, Mesa, Natalia Fortich, Ferri, Mauro, Iezzi, Giovanna, & Botticelli, Daniele. (2019). Bone healing at non-submerged implants installed with different insertion torques: a split-mouth histomorphometric randomized controlled trial [Journal-article]. International Journal of Implant Dentistry, 5(1). https://doi.org/10.1186/s40729-019-0194-2

Hirota, Atsuya, Lang, Niklaus P., Ferri, Mauro, Fortich Mesa, Natalia, Apaza Alccayhuaman, Karol Ali, & Botticelli, Daniele. (2019). Tomographic evaluation of the influence of the placement of a collagen membrane subjacent to the sinus mucosa during maxillary sinus floor augmentation: a randomized clinical trial [Journal-article]. International Journal of Implant Dentistry, 5(1). https://doi.org/10.1186/s40729-019-0183-5

Morelli, Fabrizio, Apaza Alccayhuaman, Karol Alí, Viganò, Paolo, Bengazi, Franco, Urbizo, Joaquin, Cesaretti, Gianfranco, & Botticelli, Daniele. (2019). Peri-implantitis at implants with different diameters: a pilot study in dogs [Journal-article]. International Journal of Implant Dentistry, 5(1). https://doi.org/10.1186/s40729-019-0177-3