Prof. Dr. med. Christine Bernsmeier

Schaeffer, S., Bogdanovic, A., Hildebrandt, T., Flint, E., Geng, A., Pecenko, S., Lussier, P., Strumberger, M. A., Meyer, M., Weber, J., Heim, M. H., Cajochen, C., & Bernsmeier, C. (2024). Significant nocturnal wakefulness after sleep onset in metabolic dysfunction–associated steatotic liver disease [Journal-article]. Frontiers in Network Physiology, 4. https://doi.org/10.3389/fnetp.2024.1458665

Woelfel, S., Junker, D., Bergamin, I., Meyer-Herbon, P., Stillhard, R., Graf, N., Leinenkugel, G., Dütschler, J., König, M., Kammerlander, L., Häuptle, R., Zwyssig, S., Krieger, C., Truniger, S., Koller, S., Metzger-Peter, K., Frei, N., Albrich, W. C., Friedrich, M., et al. (2024). STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease [Journal-article]. Vaccines, 12(11), 1241. https://doi.org/10.3390/vaccines12111241

Moschouri, Eleni, Salemme, Gloria, Baserga, Adriana, Cerny, Andreas, Deibel, Ansgar, Müllhaupt, Beat, Meier, Marie-Anne, Bernsmeier, Christine, Ongaro, Marie, Negro, Francesco, Grosjean, Marielle, Clerc, Olivier, Künzler-Heule, Patrizia, Semela, David, Hobi, Gabriel, Stickel, Felix, Mathieu, Adeline, Mdawar-Bailly, Elise, Faouzi, Mohamed, et al. (2024). Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis [Journal-article]. Swiss Medical Weekly, 154(6), 3698. https://doi.org/10.57187/s.3698

Moschouri, Eleni, Salemme, Gloria, Baserga, Adriana, Cerny, Andreas, Deibel, Ansgar, Müllhaupt, Beat, Meier, Marie-Anne, Bernsmeier, Christine, Ongaro, Marie, Negro, Francesco, Grosjean, Marielle, Clerc, Olivier, Künzler-Heule, Patrizia, Semela, David, Hobi, Gabriel, Stickel, Felix, Mathieu, Adeline, Mdawar-Bailly, Elise, Faouzi, Mohamed, et al. (2024). Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis [Journal-article]. Swiss Medical Weekly, 154(6), 3698. https://doi.org/10.57187/s.3698

Moschouri, E., Salemme, G., Baserga, A., Cerny, A., Deibel, A., Müllhaupt, B., Meier, M.-A., Bernsmeier, C., Ongaro, M., Negro, F., Grosjean, M., Clerc, O., Künzler-Heule, P., Semela, D., Hobi, G., Stickel, F., Mathieu, A., Mdawar-Bailly, E., Faouzi, M., et al. (2024). Real-life experience of chronic hepatitis C treatment in Switzerland: a retrospective analysis [Journal-article]. Swiss Medical Weekly, 154(6), 3698. https://doi.org/10.57187/s.3698

Flint, E., Ercan, C., Mitchell, E., Pop, O. T., Geng, A., Jorzik, P. O., Possamai, L., Brenig, R. G., Morel, S., Sieber, P., Singanayagam, A., Matter, M. S., Semela, D., Heim, M. H., Demougin, P., Roux, J., Terracciano, L. M., Triantafyllou, E., & Bernsmeier, C. (2024). Targeting the expansion of myeloid-derived suppressor cells in liver cirrhosis [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.03.29.587228

Efe, Cumali, Lytvyak, Ellina, Eşkazan, Tuğçe, Liberal, Rodrigo, Androutsakos, Theodoros, Gökçe, Dilara Turan, Beretta-Piccoli, Benedetta Terziroli, Janik, Maciej, Bernsmeier, Christine, Arvaniti, Pinelopi, Milkiewicz, Piotr, Batıbay, Ersin, Yüksekyayla, Osman, Ergenç, Ilkay, Arıkan, Çiğdem, Stättermayer, Albert Friedrich, Barutçu, Sezgin, Cengiz, Mustafa, Gül, Özlem, et al. (2024). Efficacy and Safety of Infliximab in Patients with Autoimmune Hepatitis. Hepatology. https://doi.org/10.1097/HEP.0000000000001089

Ludz, Christine, Stirnimann, Guido, Semela, David, Mertens, Joachim, Kremer, Andreas E., Filipowicz Sinnreich, Magdalena, Sokollik, Christiane, Bernsmeier, Christine, Bresson-Hadni, Solange, McLin, Valérie, Rock, Nathalie, Braegger, Christian, Posovszky, Carsten, Müller, Pascal, Cremer, Matthias, De Gottardi, Andrea, Galante, Antonio, Furlano, Raoul, Righini-Grunder, Franziska, et al. (2023). Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study [Journal-article]. Swiss Medical Weekly, 153(8), 40102. https://doi.org/10.57187/smw.2023.40102

Ludz, Christine, Stirnimann, Guido, Semela, David, Mertens, Joachim, Kremer, Andreas E., Filipowicz Sinnreich, Magdalena, Sokollik, Christiane, Bernsmeier, Christine, Bresson-Hadni, Solange, McLin, Valérie, Rock, Nathalie, Braegger, Christian, Posovszky, Carsten, Müller, Pascal, Cremer, Matthias, De Gottardi, Andrea, Galante, Antonio, Furlano, Raoul, Righini-Grunder, Franziska, et al. (2023). Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study [Journal-article]. Swiss Medical Weekly, 153(8), 40102. https://doi.org/10.57187/smw.2023.40102

Flint, E., Ercan, C., Possamai, L., Triantafyllou, E., Bernsmeier, C., Flint, E., Ercan, C., Possamai, L., Triantafyllou, E., & Bernsmeier, C. (2023). Targeting myeloid-derived suppressor cells in a carbon tetrachloride-induced murine model of chronic liver injury [Journal-article]. Journal of Hepatology, 78, S214. https://doi.org/10.1016/s0168-8278(23)00758-4

Patseas, D., Mitchell, E., Flint, E., Liu, T., Mukherjee, S., Possamai, L., McPhail, M. J. W., Bernsmeier, C., & Triantafyllou, E. (2023). Investigating the PD-1/PD-L pathway and macrophage responses in acute-on-chronic liver failure [Journal-article]. Journal of Hepatology, 78, S84–S85. https://doi.org/10.1016/s0168-8278(23)00561-5

Roth, S., Bogdanovic, A., Hildebrandt, T., Geng, A., Flint, E., Strumberger, M., Meyer, M., Heim, M., Cajochen, C., & Bernsmeier, C. (2023). Circadian sleep-wake rhythms in non-alcoholic fatty liver disease [Journal-article]. Journal of Hepatology, 78, S754–S755. https://doi.org/10.1016/s0168-8278(23)02166-9

Trovato FM, Zia R, Artru F, Mujib S, Jerome E, Cavazza A, Coen M, Wilson I, Holmes E, Morgan P, Singanayagam A, Bernsmeier C, Napoli S, Bernal W, Wendon J, Miquel R, Menon K, Patel VC, Smith J, et al. (2023). Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver failure. Journal of Hepatology, 78(3), 558–573. https://doi.org/10.1016/j.jhep.2022.10.031

Etienne S, Vosbeck J, Bernsmeier C, & Osthoff M. (2023). Prevention of Hepatitis B Reactivation in Patients Receiving Immunosuppressive Therapy: a Case Series and Appraisal of Society Guidelines. Journal of General Internal Medicine, 38(2), 490–501. https://doi.org/10.1007/s11606-022-07806-9

Brenig, R., & Bernsmeier, C. (2023). Liver Cirrhosis. Praxis, 112, 554–561.

Bütikofer, Simon, Greutmann-Yantiri, Mehtap, Gubler, Christoph, Reiner, Cecilia, Alkadhi, Hatem, Pfammatter, Thomas, Puippe, Gilbert, Santos Lopes, Bruno, Possner, Mathias, Bonassin, Francesca, Meier, Lukas, Babic, Daniela, Attenhofer Jost, Christine, Jüngst, Christoph, Müllhaupt, Beat, Bernsmeier, Christine, Schwerzmann, Markus, Tobler, Daniel, Lenggenhager, Daniela, et al. (2023). Determinants of Advanced Liver Fibrosis in Adult Patients After Fontan Palliation: Usefulness of Ultrasound Transient Elastography. Canadian Journal of Cardiology, 39, 1338–1345. https://doi.org/10.1016/j.cjca.2023.04.019

Codoni, G., Kirchner, T., Engel, B., Villamil, A. M., Efe, C., Stättermayer, A. F., Weltzsch, J. P., Sebode, M., Bernsmeier, C., Lleo, A., Gevers, T. JG., Kupčinskas, L., Castiella, A., Pinazo, J., De Martin, E., Bobis, I., Sandahl, T. D., Pedica, F., Invernizzi, F., et al. (2023). Histological and serological features of acute liver injury after SARS-CoV-2 vaccination. JHEP Reports, 5(1). https://doi.org/10.1016/j.jhepr.2022.100605

Ludz, C., Stirnimann, G., Semela, D., Mertens, J., Kremer, A. E., Sinnreich, M. F., Sokollik, C., Bernsmeier, C., Bresson-Hadni, S., McLin, V., Rock, N., Braegger, C., Posovszky, C., Müller, P., Cremer, M., De Gottardi, A., Galante, A., Furlano, R., Righini-Grunder, F., et al. (2023). Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study. Swiss Medical Weekly, 153. https://doi.org/10.57187/smw.2023.40102

Pop, Oltin-Tiberiu, Geng, Anne, Flint, Emilio, Singanayagam, Arjuna, Ercan, Caner, Possamai, Lucia, Patel, Vishal C., Kuenzler, Patrizia, Meier, Marie-Anne, Soysal, Savas, Hruz, Petr, Kollmar, Otto, Tatham, Kate C., Ward, Josie K., Müllhaupt, Beat, Weber, Achim, Wendon, Julia, Niess, Jan Hendrik, Heim, Markus, et al. (2023). AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells. Cellular and Molecular Gastroenterology and Hepatology, 16, 17–37. https://doi.org/10.1016/j.jcmgh.2023.03.007

Pop, Oltin-Tiberiu, Geng, Anne, Flint, Emilio, Singanayagam, Arjuna, Ercan, Caner, Possamai, Lucia, Patel, Vishal C., Kuenzler, Patrizia, Meier, Marie-Anne, Soysal, Savas, Hruz, Petr, Kollmar, Otto, Tatham, Kate C., Ward, Josie K., Müllhaupt, Beat, Weber, Achim, Wendon, Julia, Niess, Jan Hendrik, Heim, Markus, et al. (2023). AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells [Journal-article]. Cellular and Molecular Gastroenterology and Hepatology, 16(1), 17–37. https://doi.org/10.1016/j.jcmgh.2023.03.007

Roth, Sofia, Flint, Emilio, Ghataore, Lea, Patel, Vishal C., Singanayagam, Arjuna, Vincent, Royce P., Triantafyllou, Evangelos, Ma, Yun, Bernal, William, Auzinger, Georg, Heneghan, Michael, Antoniades, Charalambos, Christ-Crain, Mirjam, McPhail, Mark J.W., Taylor, David R., Wendon, Julia, & Bernsmeier, Christine. (2023). Low Baseline but Not Delta Cortisol Relates to 28-Day Transplant-Free Survival in Acute and Acute-on-Chronic Liver Failure. Gastro Hep Advances, 2, 72–82. https://doi.org/10.1016/j.gastha.2022.08.006

Schaeffer, Sofia, Lutz, Christian, Dobbie, Michael, Terracciano, Luigi M., Matter, Matthias, Vosbeck, Jürg, Heim, Markus H., & Bernsmeier, Christine. (2023). Ribociclib-induced liver injury: a case report. Frontiers in Oncology, 13. https://doi.org/10.3389/fonc.2023.1256783

Uzun, Sarp, Zinner, Carl P., Beenen, Amke C., Alborelli, Ilaria, Bartoszek, Ewelina M., Bartoszek, Ewelina M., Yeung, Jason, Calgua, Byron, Reinscheid, Matthias, Bronsert, Peter, Stalder, Anna K., Haslbauer, Jasmin D., Vosbeck, Juerg, Mazzucchelli, Luca, Hoffmann, Tobias, Terracciano, Luigi M., Hutter, Gregor, Manz, Michael, Panne, Isabelle, et al. (2023). Morphologic and molecular analysis of liver injury after SARS-CoV-2 vaccination reveals distinct characteristics. Journal of Hepatology, 79, 666–676. https://doi.org/10.1016/j.jhep.2023.05.020

Efe C, Kulkarni AV, Terziroli Beretta-Piccoli B, Magro B, Stättermayer A, Cengiz M, Clayton-Chubb D, Lammert C, Bernsmeier C, Gül Ö, la Tijera FH, Anders M, Lytvyak E, Akın M, Purnak T, Liberal R, Peralta M, Ebik B, Duman S, et al. (2022). Liver injury after SARS-CoV-2 vaccination: Features of immune-mediated hepatitis, role of corticosteroid therapy and outcome. Hepatology (Baltimore, Md.), 76(6), 1576–1586. https://doi.org/10.1002/hep.32572

Guri Y, Vosbeck J, Dickenmann M, Jetter A, & Bernsmeier C. (2022). Exacerbation of familial intrahepatic cholestasis in conjunction with COVID-19 vaccination. (Patent No. 3). 77(3), Article 3. https://doi.org/10.1016/j.jhep.2022.05.003

Geng, A., Brenig, R. G., Lütge, M., Roux, J., Cheng, H.-W., Kuenzler, P., Semela, D., Heim, M., Ludewig, B., & Bernsmeier, C. (2022). Heterogeneity of peripheral blood monocytes in patients with cirrhosis [Journal-article]. Journal of Hepatology, 77, S192–S193. https://doi.org/10.1016/s0168-8278(22)00759-0

Khamri W, Gudd C, Liu T, Nathwani R, Krasniqi M, Azam S, Barbera T, Trovato FM, Possamai L, Triantafyllou E, Seoane RC, Lebosse F, Singanayagam A, Kumar N, Bernsmeier C, Mukherjee S, McPhail M, Weston CJ, Antoniades CG, & Thursz MR. (2022). Suppressor CD4(+) T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis. Gut, 71(6), 1192–1202. https://doi.org/10.1136/gutjnl-2021-324071

Flint, E., Triantafyllou, E., & Bernsmeier, C. (2022). TAM Receptors in the Pathophysiology of Liver Disease. Livers, 2, 15–29. https://doi.org/10.3390/livers2010002

Geng, Anne, Flint, Emilio, & Bernsmeier, Christine. (2022). Plasticity of monocytes and macrophages in cirrhosis of the liver. Frontiers in Network Physiology, 2. https://doi.org/10.3389/fnetp.2022.937739

Sofia Roth, Emilio Flint, Lea Ghataore, Vishal C. Patel, Arjuna Singanayagam, Royce P. Vincent, Evangelos Triantafyllou, Yun Ma, William Bernal, Georg Auzinger, Michael Heneghan, Charalambos Antoniades, Mirjam Christ-Crain, Mark J.W. McPhail, David R. Taylor, Julia Wendon, & Christine Bernsmeier. (2022). Low Baseline but Not Delta Cortisol Relates to 28-Day Transplant-Free Survival in Acute and Acute-on-Chronic Liver Failure. Gastro Hep Advances, 1(2), 72–82. https://doi.org/10.1016/j.gastha.2022.08.006

Van der Merwe S., Chokshi S., Bernsmeier C., & Albillos A. (2021). The multifactorial mechanisms of bacterial infection in decompensated cirrhosis. Journal of Hepatology, 75, S82–S100. https://doi.org/10.1016/j.jhep.2020.11.029

Triantafyllou E, Gudd CL, Mawhin MA, Husbyn HC, Trovato FM, Siggins MK, O’Connor T, Kudo H, Mukherjee SK, Wendon JA, Bernsmeier C, Goldin RD, Botto M, Khamri W, McPhail MJ, Possamai LA, Woollard KJ, Antoniades CG, & Thursz MR. (2021). PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury. The Journal of Clinical Investigation, 131(4). https://doi.org/10.1172/jci140196

Kronlage C, Hardmeier M, Bally S, Scholz MC, Bucher HC, Müller OK, Winterhalder C., Mongiat M, Müller J, Polymeris A, Weber M, Lausberg C, Kassi E, Kuhle J, Kappos L, Hermann W, Bernsmeier C, & Yaldizli Ö. (2020). Muscle stiffness, gait instability, and liver cirrhosis in Wilson’s disease. Lancet (London, England), 396(10256), 990. https://doi.org/10.1016/s0140-6736(20)31963-2

Bernsmeier C, & McPhail MJW. (2020). Editorial: outcome prediction in patients with cirrhosis and acute-on-chronic liver failure-authors’ reply. (Patent No. 7). 52(7), Article 7. https://doi.org/10.1111/apt.16053

Bernsmeier C, Cavazza A, Fatourou EM, Theocharidou E, Akintimehin A, Baumgartner B, Dhar A, Auzinger G, Thursz M, Bernal W, Wendon JA, Karvellas CJ, Antoniades CG, & McPhail MJW. (2020). Leucocyte ratios are biomarkers of mortality in patients with acute decompensation of cirrhosis and acute-on-chronic liver failure. Alimentary Pharmacology & Therapeutics, 52(5), 855–865. https://doi.org/10.1111/apt.15932

Pop, O.-T., Brenig, R. G., Triantafyllou, E., Geng, A., Singanayagam, A., Kuenzler, P., Hruz, P., Wendon, J., Niess, J. H., Heim, M., Semela, D., Antoniades, H., Possamai, L., Terracciano, L. M., & Bernsmeier, C. (2020). AXL-expressing homeostatic liver macrophages are reduced in patients with progression of cirrhosis [Journal-article]. Journal of Hepatology, 73, S30–S31. https://doi.org/10.1016/s0168-8278(20)30615-2

Bernsmeier C, van der Merwe S, & Périanin A. (2020). Innate immune cells in cirrhosis. Journal of Hepatology, 73(1), 186–201. https://doi.org/10.1016/j.jhep.2020.03.027

Leuenberger, A. B., Bernsmeier, C., Bingisser, R., & Mansella, G. (2020). Die junge ikterische Patientin [Journal-article]. Swiss Medical Forum ‒ Schweizerisches Medizin-Forum. https://doi.org/10.4414/smf.2020.08389

Brenig R, Pop OT, Triantafyllou E, Geng A, Singanayagam A, Perez-Shibayama C, Besse L, Cupovic J, Künzler P, Boldanova T, Brand S, Semela D, Duong FH, Weston CJ, Ludewig B, Heim MH, Wendon J, Antoniades CG, & Bernsmeier C. (2020). Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis. Life Science Alliance, 3(1). https://doi.org/10.26508/lsa.201900465

Keerl C, & Bernsmeier C. (2020). [Elevated liver function tests - as incidental finding in general practice]. Therapeutische Umschau. Revue Therapeutique, 77(8), 371–378. https://doi.org/10.1024/0040-5930/a001206

Kronlage, Cornelius, Hardmeier, Martin, Bally, Seraina, Scholz, Marleen Carina, Bucher, Heiner C, Müller, Olivia Katharina, Winterhalder, Clemens, Mongiat, Michel, Müller, Jannis, Polymeris, Alexandros, Weber, Martin, Lausberg, Christina, Kassi, Elianne, Kuhle, Jens, Kappos, Ludwig, Hermann, Wieland, Bernsmeier, Christine, & Yaldizli, Özgür. (2020). Muscle stiffness, gait instability, and liver cirrhosis in Wilson’s disease. Lancet (London, England), 396(10256), 990. https://doi.org/10.1016/s0140-6736(20)31963-2

Triantafyllou, E., Gudd, C., Nathwani, R., Trovato, F., Possamai, L., Morrison, R., Bernsmeier, C., Patel, V., Khamri, W., Goldin, R., Wendon, J., McPhail, M., Woollard, K., Thursz, M., & Antoniades, C. (2019). FRI-099-PD-1+ monocytes and macrophages contribute to impaired microbial clearance following acute liver failure [Journal-article]. Journal of Hepatology, 70(1), e430–e431. https://doi.org/10.1016/s0618-8278(19)30846-1

Singanayagam, A., Erminelli, D., Triantafyllou, E., Bernsmeier, C., Tunc, E., Krasniqi, M., Patel, V., Lebossé, F., Nathwani, R., Atkinson, A., Dhar, A., Heneghan, M., Auzinger, G., Khamri, W., Adams, D., Wendon, J., Thursz, M., McPhail, M. J. W., & Antoniades, H. (2019). THU-052-Immunometabolic profiling of ascites from patients with acute-on-chronic liver failure reveals increased MerTK+ immunosuppressive myeloid cells and cell death markers with preferential lipid metabolism compared to cirrhosis without organ failure [Journal-article]. Journal of Hepatology, 70(1), e183. https://doi.org/10.1016/s0618-8278(19)30335-4

Ruperti-Repilado, Francisco Javier, Haefliger, Simon, Rehm, Sophia, Zweier, Markus, Rentsch, Katharina M., Rentsch, Katharina M., Blum, Johannes, Jetter, Alexander, Heim, Markus, Leuppi-Taegtmeyer, Anne, Terracciano, Luigi, & Bernsmeier, Christine. (2019). Danger of Herbal Tea: A Case of Acute Cholestatic Hepatitis Due to; Artemisia annua; Tea. Frontiers in medicine, 6, 221. https://doi.org/10.3389/fmed.2019.00221

Bernsmeier, C., & De Gottardi, A. (2018). Hepatologie: Die Leberzirrhose ist nicht mehr die Leberzirrhose! [Journal-article]. Swiss Medical Forum ‒ Schweizerisches Medizin-Forum. https://doi.org/10.4414/smf.2018.08015

Mensing B, Nowak A, Zweifel S, Terracciano L, Bernsmeier C, & Filipowicz Sinnreich M. (2018). [Wilson’s disease or hepatolenticular degeneration]. Therapeutische Umschau. Revue therapeutique, 75(4), 241–248. https://doi.org/10.1024/0040-5930/a000995

Bernsmeier C, Triantafyllou E, Brenig R, Lebosse FJ, Singanayagam A, Patel VC, Pop OT, Khamri W, Nathwani R, Tidswell R, Weston CJ, Adams DH, Thursz MR, Wendon JA, & Antoniades CG. (2018). CD14(+) CD15(-) HLA-DR(-) myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure. Gut, 67(6), 1155–1167. https://doi.org/10.1136/gutjnl-2017-314184

Triantafyllou E, Pop OT, Possamai LA, Wilhelm A, Liaskou E, Singanayagam A, Bernsmeier C, Khamri W, Petts G, Dargue R, Davies SP, Tickle J, Yuksel M, Patel VC, Abeles RD, Stamataki Z, Curbishley SM, Ma Y, Wilson ID, et al. (2018). MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. Gut, 67(2), 333–347. https://doi.org/10.1136/gutjnl-2016-313615

Khamri W, Abeles RD, Hou TZ, Anderson AE, El-Masry A, Triantafyllou E, Bernsmeier C, Larsen FS, Singanayagam A, Kudo N, Possamai LA, Lebosse F, Auzinger G, Bernal W, Willars C, Weston CJ, Lombardi G, Wendon J, Thursz M, & Antoniades CG. (2017). Increased Expression of Cytotoxic T-Lymphocyte-Associated Protein 4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure. Gastroenterology, 153(1), 263–276. https://doi.org/10.1053/j.gastro.2017.03.023

Bernsmeier C, & Albano E. (2017). Liver dendritic cells and NAFLD evolution: A remaining open issue. (Patent No. 6). 66(6), Article 6. https://doi.org/10.1016/j.jhep.2017.02.018

Vergis N, Khamri W, Beale K, Sadiq F, Aletrari MO, Moore C, Atkinson SR, Bernsmeier C, Possamai LA, Petts G, Ryan JM, Abeles RD, James S, Foxton M, Hogan B, Foster GR, O’Brien AJ, Ma Y, Shawcross DL, et al. (2017). Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase. Gut, 66(3), 519–529. https://doi.org/10.1136/gutjnl-2015-310378

Bernsmeier, Christine, Dill, Michael T., Provenzano, Angela, Makowska, Zuzanna, Krol, Ilona, Muscogiuri, Giovanna, Semela, David, Tornillo, Luigi, Marra, Fabio, Heim, Markus H., & Duong, François H. T. (2016). Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation. Laboratory Investigation, 96(9), 972–980. https://doi.org/10.1038/labinvest.2016.75

Khamri, W., Abeles, D., Hou, T., Anderson, A., Bernsmeier, C., Vergis, N., Auzinger, G., Bernal, W., Willars, C., Robinson, J., Lombardi, G., Sansom, D., Wendon, J., Thursz, M., & Antoniades, C. (2016). CTLA-4 IS A NEGATIVE REGULATOR OF T CELL ACTIVATION IN ACUTE LIVER FAILURE. 64, S152–S152. ELSEVIER SCIENCE BV.

Larsen FS, Schmidt LE, Bernsmeier C, Rasmussen A, Isoniemi H, Patel VC, Triantafyllou E, Bernal W, Auzinger G, Shawcross D, Eefsen M, Bjerring PN, Clemmesen JO, Hockerstedt K, Frederiksen HJ, Hansen BA, Antoniades CG, & Wendon J. (2016). High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial. Journal of hepatology, 64(1), 69–78. https://doi.org/10.1016/j.jhep.2015.08.018

Manakkat Vijay GK, Ryan JM, Abeles RD, Ramage S, Patel V, Bernsmeier C, Riva A, McPhail MJ, Tranah TH, Markwick LJ, Taylor NJ, Bernal W, Auzinger G, Willars C, Chokshi S, Wendon JA, Ma Y, & Shawcross DL. (2016). Neutrophil Toll-Like Receptor 9 Expression and the Systemic Inflammatory Response in Acetaminophen-Induced Acute Liver Failure. Critical care medicine, 44(1), 43–53. https://doi.org/10.1097/ccm.0000000000001309

Mukherjee, S. K., Pop, O. T., Triantafyllou, E., Khamri, W., Bernsmeier, C., Li, K. -K., Suddle, A., Weston, C., Curbishley, S., Thursz, M., Adams, D., Heaton, N., Quaglia, A., & Antoniades, C. G. (2016). MER TYROSINE KINASE POSITIVE TUMOUR ASSOCIATED MACROPHAGES ARE A NOVEL THERAPEUTIC TARGET IN HEPATOCELLULAR CARCINOMA. 64, S574–S575. ELSEVIER SCIENCE BV.

Patel, V. C., Leong, L. E. X., Koller, G., Knapp, S., Lai, G., Singanayagam, A., Bernsmeier, C., McPhail, M. J. W., Shawcross, D. L., Antoniades, C. G., Thursz, M., Wendon, J. A., Rogers, G. B., & Bruce, K. D. (2016). ALTERED GUT MICROBIAL PROFILE IS A PROPONENTOF BACTERIAL TRANSLOCATION IN ACUTE- ON- CHRONIC LIVER FAILURE. 64, S453–S454. ELSEVIER SCIENCE BV.

Singanayagam, A., Triantafyllou, E., Patel, V. C., Bernsmeier, C., Weston, C., Curbishley, S., Willars, C., Bernal, W., Auzinger, G., Heneghan, M., Dhar, A., Adams, D., Thursz, M., Wendon, J., & Antoniades, C. G. (2016). MER TYROSINE KINASE REGULATES THE ACTIVATION OF MYELOID CELLS AND INNATE IMMUNE RESPONSES IN ACUTE-ON-CHRONIC LIVER FAILURE. 64, S143–S143. ELSEVIER SCIENCE BV.

Triantafyllou, E., Wilhelm, A., Possamai, L., Pop, O., Liaskou, E., Bernsmeier, C., Khamri, W., Petts, G., Davies, S., Abeles, R., Stamataki, Z., Woollard, K., Ma, Y., Quaglia, A., Wendon, J., Thursz, M., Adams, D., Curbishley, S., Weston, C., & Antoniades, C. (2016). SECRETORY LEUKOCYTE PROTEASE INHIBITOR DRIVES HEPATIC RESOLUTION RESPONSES IN ACUTE LIVER FAILURE THROUGH MODULATION OF THE MER TYROSINE KINASE PATHWAY. 64, S512–S512. ELSEVIER SCIENCE BV.

Bernsmeier, C., Patel, V. C., Singanayagam, A., Yuksel, M., Huang, X., Willars, C., Bernal, W., Auzinger, G., Ma, Y., Larsen, F. S., Wendon, J. A., & Antoniades, C. G. (2015). THERAPEUTIC PLASMA EXCHANGE MODULATES INNATE IMMUNE ACTIVATION AND IMPROVES OUTCOME IN PATIENTS WITH ACUTE LIVER FAILURE. 62, S246–S247. ELSEVIER SCIENCE BV.

Bernsmeier, C., Tidswell, R., Ghataore, L., Patel, V. C., Singanayagam, A., Triantafyllou, E., Khamri, W., Heneghan, M., Willars, C., Bernal, W., Auzinger, G., Taylor, D. R., Vincent, R. P., Ma, Y., Thursz, M. R., Wendon, J. A., & Antoniades, C. G. (2015). PROOF-OF-PRINCIPLE EVALUATION OF IMMUNOMODULATORY DRUGS IN PROMOTING PHAGOCYTOSIS CAPACITY IN PATIENTS WITH LIVER FAILURE. 62, S324–S324. ELSEVIER SCIENCE BV.

McPhail, M. J., Bernsmeier, C., Fatourou, E., Dhar, A., Auzinger, G., Willars, C., Bernal, W., Thursz, M., Antoniades, C., & Wendon, J. A. (2015). DIFFERENTIAL LEUKOCYTE COUNT AS AN ADJUNCTIVE BIOMARKER OF OUTCOME IN PATIENTS WITH ACUTE-ON-CHRONIC LIVER FAILURE. 62, S360–S360. ELSEVIER SCIENCE BV.

Triantafyllou, E., Liaskou, E., Khamri, W., Pop, O. T., Davies, S., Bernsmeier, C., Stamataki, Z., Goldin, R. D., Ma, Y., Quaglia, A., Thursz, M. R., Wendon, J., Curbishley, S. M., Weston, C. J., Adams, D. H., & Antoniades, C. G. (2015). SECRETORY LEUKOCYTE PROTEASE INHIBITOR (SLPI) SUPPRESSES INNATE IMMUNE RESPONSES AND PROMOTES RESOLUTION OF INFLAMMATION IN AN AUTO/PARACRINE MANNER DURING ACUTE LIVER FAILURE (ALF). 62, S500–S501. ELSEVIER SCIENCE BV.

Bernsmeier C, Pop OT, Singanayagam A, Triantafyllou E, Patel VC, Weston CJ, Curbishley S, Sadiq F, Vergis N, Khamri W, Bernal W, Auzinger G, Heneghan M, Ma Y, Jassem W, Heaton ND, Adams DH, Quaglia A, Thursz MR, et al. (2015). Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK. Gastroenterology, 148(3), 603–615. https://doi.org/10.1053/j.gastro.2014.11.045

Bernsmeier, Christine, Weisskopf, Diego M., Pflueger, Marlon O., Mosimann, Jan, Campana, Benedetta, Terracciano, Luigi, Beglinger, Christoph, Heim, Markus H., & Cajochen, Christian. (2015). Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls. PLoS ONE, 10(11), e0143293. https://doi.org/10.1371/journal.pone.0143293

Bernsmeier C, Singanayagam A, Patel VC, Wendon J, & Antoniades CG. (2015). Immunotherapy in the treatment and prevention of infection in acute-on-chronic liver failure. Immunotherapy, 7(6), 641–654. https://doi.org/10.2217/imt.15.27

Bernsmeier C, Antoniades CG, & Wendon J. (2014). What’s new in acute liver failure? Intensive care medicine, 40(10), 1545–1548. https://doi.org/10.1007/s00134-014-3350-4

Bernsmeier, C., Patel, V., Singanayagam, A., Willars, C., Bernal, W., Auzinger, G., Antoniades, C. G., & Wendon, J. (2014). EARLY PLASMA EXCHANGE ALLEVIATES PRO-INFLAMMATORY CYTOKINE SECRETION OF PERIPHERAL MONOCYTES IN PATIENTS WITH ACUTE LIVER FAILURE. 40, S30–S30. SPRINGER.

Antoniades CG, Khamri W, Abeles RD, Taams LS, Triantafyllou E, Possamai LA, Bernsmeier C, Mitry RR, O’Brien A, Gilroy D, Goldin R, Heneghan M, Heaton N, Jassem W, Bernal W, Vergani D, Ma Y, Quaglia A, Wendon J, & Thursz M. (2014). Secretory leukocyte protease inhibitor: a pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure. Hepatology (Baltimore, Md.), 59(4), 1564–1576. https://doi.org/10.1002/hep.26933

Bernsmeier, C., Patel, V., Tidswell, R., Triantafyllou, E., Singanayagam, A., Khamri, W., Agarwal, K., Heneghan, M., Willars, C., Bernal, W., Auzinger, G., Ma, Y., Thursz, M., Wendon, J., & Antoniades, C. G. (2014). MONOCYTE EXHAUSTION: A MECHANISTIC EXPLANATION FOR SUSCEPTIBILITY TO INFECTION IN LIVER FAILURE. 60, S120–S121. ELSEVIER SCIENCE BV.

Bernsmeier, C., Weisskopf, D. M., Mosimann, J., Campana, B., Meyer-Gerspach, A. C., Steinert, R. E., Blaser, L., Jeker, L., Terracciano, L., Beglinger, C., Heim, M. H., & Cajochen, C. (2014). DAYTIME SLEEPINESS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE IS LINKED TO INSULIN RESISTANCE, ELEVATED LIVER FUNCTION TESTS AND FIBROSIS. 60, S354–S354. ELSEVIER SCIENCE BV.

Vergis, N., Khamri, W., Atkinson, S., Tidswell, R., Gill, U., Ryan, J., Bernsmeier, C., Triantafyllou, E., Blackmore, L., Moore, C., Marcinkowski, H., Possamai, L., Mullish, B., Khan, S., Dhar, A., Foxton, M., Shawcross, D., Ma, Y., Antoniades, C. G., & Thursz, M. R. (2014). MONOCYTE OXIDATIVE BURST DEFECT PREDICTS RISK OF INFECTION IN ALCOHOLIC HEPATITIS. 60, S168–S168. ELSEVIER SCIENCE BV.

Balmer, Maria L., Slack, Emma, de Gottardi, Andrea, Lawson, Melissa A. E., Hapfelmeier, Siegfried, Miele, Luca, Grieco, Antonio, Van Vlierberghe, Hans, Fahrner, René, Patuto, Nicola, Bernsmeier, Christine, Ronchi, Francesca, Wyss, Madeleine, Stroka, Deborah, Dickgreber, Nina, Heim, Markus H., McCoy, Kathy D., & Macpherson, Andrew J. (2014). The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota. Science Translational Medicine, 6(237), 237ra66. https://doi.org/10.1126/scitranslmed.3008618

Bernsmeier, Christine, Calabrese, Diego, Heim, Markus H., & Duong, H. T. F. (2014). Hepatitis C virus dysregulates glucose homeostasis by a dual mechanism involving induction of PGC1α and dephosphorylation of FoxO1. Journal of Viral Hepatitis, 21(1), 9–18. https://doi.org/10.1111/jvh.12208

Bernsmeier, Christine, Pop, Oltin T., Triantafyllou, Evangelos, Weston, Chris J., Curbishley, Stuart M., Patel, Vishal C., Singanayagam, Arjuna, Khamri, Wafa, Willars, Christopher, Bernal, William, Auzinger, Georg, Heneghan, Michael A., Ma, Yun, Jassem, Wayel, Heaton, Nigel, Adams, David H., Thursz, Mark R., Quaglia, Alberto, Wendon, Julia, & Antoniades, Charalambos G. (2014). Inhibition of MER receptor tyrosine kinase in patients with acute on chronic liver failure: a potential target for immunotherapy? HEPATOLOGY, 60, 489A–489A.

Bernsmeier C, Meyer-Gerspach AC, Blaser LS, Jeker L, Steinert RE, Heim MH, & Beglinger C. (2014). Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic fatty liver disease. PloS one, 9(1), e87488. https://doi.org/10.1371/journal.pone.0087488

Patel, Vishal C., Knapp, Susanne, Lai, Glory Y., Bernsmeier, Christine, Singanayagam, Arjuna, McPhail, Mark J., Willars, Christopher, Bernal, William, Auzinger, Georg, Heneghan, Michael A., Menon, Krishna, Jassem, Wayel, Srinivasan, Parthi, Prachalias, Andreas, Vilca-Melendez, Hector, Heaton, Nigel, Thursz, Mark R., Wendon, Julia, & Antoniades, Charalambos G. (2014). Bacterial translocation in liver failure: a possible mechanism of impaired innate immune responses and immuneparesis? HEPATOLOGY, 60, 493A–493A.

Triantafyllou, Evangelos, Pop, Oltin T., Liaskou, Evaggelia, Bernsmeier, Christine, Khamri, Wafa, Stamataki, Zania, Ma, Yun, Thursz, Mark R., Wendon, Julia, Quaglia, Alberto, Weston, Chris J., Curbishley, Stuart M., Adams, David H., & Antoniades, Charalambos G. (2014). Secretory Leukocyte Protease Inhibitor (SLPI) promotes hepatic resolution responses in acute liver failure (ALF). 60, 560A–560A. WILEY-BLACKWELL.

Vijay, Godhev K. Manakkat, Vizcay-Barrena, Gema, Tranah, Thomas, Glover, Leanne, Patel, Vishal C., Bernsmeier, Christine, Ryan, Jennifer M., Blackmore, Laura J., Huang, Xiaohong, Kronsten, Victoria T., Taylor, Nicholas J., Bernal, William, Auzinger, Georg, Willars, Christopher, Wendon, Julia, Ma, Yun, Bain, Barbara, Warley, Alice, & Shawcross, Debbie. (2014). Increased neutrophil actin production and translocation of myeloperoxidase in patients with acetaminophen-induced acute liver failure may contribute to multiorgan failure. 60, 558A–559A. WILEY-BLACKWELL.

Huber X, Droeser RA, Bernsmeier C, & Kirchhoff P. (2013). When a colonoscopy becomes a duodenoscopy: a palliative treatment of a malignant sigmoidoduodenal fistula. BMJ Case Reports, 2013. https://doi.org/10.1136/bcr-2012-008241

Bernsmeier, C., Meyer-Gerspach, A. C., Blaser, L. S., Jeker, L., Steinert, R. E., Heim, M. H., & Beglinger, C. (2013). GLUCOSE-INDUCED GLUCAGON-LIKE PEPTIDE 1 SECRETION IS DEFICIENT IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE. 58, S531–S531. ELSEVIER SCIENCE BV.

Bernsmeier, C., Dill, M. T., Provenzano, A., Makowska, Z., Huser, K., Semela, D., Tornillo, L., Marra, F., & Heim, M. H. (2012). NOTCH1 DELETION IN HEPATOCYTES PREDISPOSES TO DIABETES AND LIVER STEATOSIS THROUGH DYSREGULATION OF GENES INVOLVED IN GLUCOSE AND LIPID HOMEOSTASIS. 56, S42–S42. ELSEVIER SCIENCE BV.

Rosin C, Bernsmeier C, Entenza JM, Moreillon P, Frei R, Weisser M, & Flückiger U. (2012). Daptomycin for highly resistant Enterococcus faecium infection. Swiss medical weekly, 142, w13603. https://doi.org/10.4414/smw.2012.13603

Bernsmeier, C., & Heim, M. (2011). Nicht-alkoholische Fettleber und Steatohepatitis [Journal-article]. Swiss Medical Forum ‒ Schweizerisches Medizin-Forum, 11(04). https://doi.org/10.4414/smf.2011.07418

Bernsmeier,C, & Heim,MH. (2011). Non-alcoholic fatty liver disease and steatohepatitis: Hepatic manifestations of the metabolic syndrome. 11(5), 53–57.

Bernsmeier C., Nickel C., Bingisser R., & Kim M.J. (2010). Urinary tract infection presenting with nonspecific complaints and normal urinalysis in 84-year-old woman. American Journal of Case Reports, 11, 116–118.

Filipowicz, Magdalena, Bernsmeier, Christine, Terracciano, Luigi, Duong, Francois H. T., & Heim, Markus H. (2010). S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse. PLoS ONE, 5(11), e15492. https://doi.org/10.1371/journal.pone.0015492

Osthoff M, Bernsmeier C, Marsch SC, & Hunziker PR. (2010). Levosimendan as treatment option in severe verapamil intoxication: a case report and review of the literature. 2010. https://doi.org/10.1155/2010/546904

Bernsmeier C, & Heim MH. (2009). Insulin resistance in chronic hepatitis C: mechanisms and clinical relevance. Swiss medical weekly, 139(47-48), 678–684. https://doi.org/10.4414/smw.2009.12765

Bernsmeier C., & Heim M.H. (2009). Insulin resistance in chronic hepatitis C: Mechanisms and clinical relevance. Swiss Medical Weekly, 139(47-48), 678–684.

Bernsmeier, Christine, Keller, Ulrich, Terracciano, Luigi, & Heim, Markus. (2009). NAFLD or NASH - insights from a longitudinal cohort study. 139, 20S–20S. E M H SWISS MEDICAL PUBLISHERS LTD.

Heim, M. H., Sarasin-Filipowicz, M., Bernsmeier, C., & Duong, F. (2009). 614 S-ADENOSYL-METHIONINE (SAME) IMPROVES EARLY VIROLOGICAL RESPONSE IN CHRONIC HEPATITIS C PATIENTS WITH PREVIOUS NON-RESPONSE [Journal-article]. Journal of Hepatology, 50, S226. https://doi.org/10.1016/s0168-8278(09)60616-4

Bernsmeier, C., Duong, F. H. T., Lin, S., & Heim, M. H. (2009). DYSREGULATION OF GLUCONEOGENESIS IN CHRONIC HEPATITIS C: THE ROLE OF PROTEIN PHOSPHATASE 2A. 50, S123–S124. ELSEVIER SCIENCE BV.

Heim, M. H., Sarasin-Filipowicz, M., Bernsmeier, C., & Duong, F. (2009). S-ADENOSYL-METHIONINE (SAME) IMPROVES EARLY VIROLOGICAL RESPONSE IN CHRONIC HEPATITIS C PATIENTS WITH PREVIOUS NON-RESPONSE. JOURNAL OF HEPATOLOGY, 50, S226–S226.

Bernsmeier, Christine, Duong, Francois H T, Christen, Verena, Pugnale, Paolo, Negro, Francesco, Terracciano, Luigi, & Heim, Markus H. (2008). Virus-induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C. Journal of Hepatology, 49(3), 429–440. https://doi.org/10.1016/j.jhep.2008.04.007

Bernsmeier, Christine, Duong, Francois, Christen, Verena, Terracciano, Luigi, & Heim, Markus. (2007). PP2A overexpression in chronic hepatitis C inhibits insulin signaling in the liver. 46, 239A–240A. JOHN WILEY & SONS INC.

Christen V, Duong F, Bernsmeier C, Sun D, Nassal M, & Heim MH. (2007). Inhibition of alpha interferon signaling by hepatitis B virus. Journal of virology, 81(1), 159–165. https://doi.org/10.1128/jvi.01292-06

von Wagner,Michael, Huber,Miriam, Berg,Thomas, Hinrichsen,Holger, Rasenack,Jens, Heintges,Tobias, Bergk,Alexandra, Bernsmeier,Christine, Häussinger,Dieter, Herrmann,Eva, & Zeuzem,Stefan. (2005). Peginterferon-alpha-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C. Gastroenterology (Print-Ausgabe), 129(6), 522–527.

von Wagner, M, Huber, M, Berg, T, Hinrichsen, H, Rasenack, J, Heintges, T, Bergk, A, Bernsmeier, C, & Zeuzem, S. (2004). Randomized multicenter study comparing 16 vs. 24 weeks of combination therapy with peginterferon alfa-2a plus ribavirin in patients chronically infected with HCV genotype 2 or 3. HEPATOLOGY, 40, 725A–725A.