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Dr.
Valentin Köhler
Department of Chemistry
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34 found
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Hua, Yong, Zou, Zhi, Prescimone, Alessandro, Ward, Thomas R, Mayor, Marcel, & Köhler, Valentin. (2024). NSPs: chromogenic linkers for fast, selective, and irreversible cysteine modification [Journal-article]. Chemical Science, 15(28), 10997–11004. https://doi.org/10.1039/d4sc01710b
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Strauß, Marcel, Shayeghi, Armin, Mauser, Martin F. X., Geyer, Philipp, Kostersitz, Tim, Salapa, Julia, Dobrovolskiy, Oleksandr, Daly, Steven, Commandeur, Jan, Hua, Yong, Köhler, Valentin, Mayor, Marcel, Benserhir, Jad, Bruschini, Claudio, Charbon, Edoardo, Castaneda, Mario, Gevers, Monique, Gourgues, Ronan, Kalhor, Nima, et al. (2023). Highly sensitive single-molecule detection of macromolecule ion beams [Journal-article]. Science Advances, 9(48). https://doi.org/10.1126/sciadv.adj2801
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Hua, Yong, Strauss, Marcel, Fisher, Sergey, Mauser, Martin F. X., Manchet, Pierre, Smacchia, Martina, Geyer, Philipp, Shayeghi, Armin, Pfeffer, Michael, Eggenweiler, Tim Henri, Daly, Steven, Commandeur, Jan, Mayor, Marcel, Arndt, Markus, Šolomek, Tomáš, & Köhler, Valentin. (2023). Giving the Green Light to Photochemical Uncaging of Large Biomolecules in High Vacuum [Journal-article]. JACS Au, 3(10), 2790–2799. https://doi.org/10.1021/jacsau.3c00351
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Hua, Yong, Zou, Zhi, Prescimone, Alessandro, Ward, Thomas R., Mayor, Marcel, & Köhler, Valentin. (2023). Click, Lock & Dye: a chromogenic handle for selective cysteine modification [Posted-content]. In Chemrxiv. Cambridge University Press. https://doi.org/10.26434/chemrxiv-2023-83gph
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Yu, Kun, Zou, Zhi, Igareta, Nico V., Tachibana, Ryo, Bechter, Julia, Köhler, Valentin, Chen, Dongping, & Ward, Thomas R. (2023). Artificial Metalloenzyme-Catalyzed Enantioselective Amidation via Nitrene Insertion in Unactivated C( sp 3 )–H Bonds [Journal-article]. Journal of the American Chemical Society, 145(30), 16621–16629. https://doi.org/10.1021/jacs.3c03969
Zaitseva, Snizhana, Prescimone, Alessandro, & Köhler, Valentin. (2023). Enantioselective Allylation of Stereogenic Nitrogen Centers. Organic Letters, 25(10), 1649–1654. https://doi.org/10.1021/acs.orglett.3c00195
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Strauß, Marcel, Shayeghi, Armin, Mauser, Martin, Manchet, Pierre, Smacchia, Martina, Salapa, Julia, Kostersitz, Tim, Geyer, Philipp, Daly, Steven, Commandeur, Jan, Hua, Yong, di Silvestro, Alfredo, Mayor, Marcel, Köhler, Valentin, Benserhir, Jad, Bruschini, Claudio, Charbon, Edoardo, Castaneda, Mario, Gevers, Monique, et al. (2023). Superconducting quantum detectors and single photon charge control for mass spectrometry [Proceedings-article]. In Shahriar, Selim M.;Scheuer, Jacob (Ed.), SPIE Quantum West (Vol. 12447). SPIE. https://doi.org/10.1117/12.2657258
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Gerlich, Stefan, Fein, Yaakov Y., Shayeghi, Armin, Köhler, Valentin, Mayor, Marcel, & Arndt, Markus. (2021). Otto Stern’s Legacy in Quantum Optics: Matter Waves and Deflectometry. In Molecular Beams in Physics and Chemistry (pp. 547–573). Springer International Publishing. https://doi.org/10.1007/978-3-030-63963-1_24
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Schätti, Jonas, Köhler, Valentin, Mayor, Marcel, Fein, Yaakov Y., Geyer, Philipp, Mairhofer, Lukas, Gerlich, Stefan, & Arndt, Markus. (2020). Matter-wave interference and deflection of tripeptides decorated with fluorinated alkyl chains. Journal of Mass Spectrometry, 55(6), e4514. https://doi.org/10.1002/jms.4514
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Schätti, Jonas, Kriegleder, Moritz, Debiossac, Maxime, Kerschbaum, Michael, Geyer, Philipp, Mayor, Marcel, Arndt, Markus, & Köhler, Valentin. (2019). Neutralization of insulin by photocleavage under high vacuum. Chemical Communications, 55(83), 12507–12510. https://doi.org/10.1039/c9cc05712a
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Debiossac, M., Schätti, J., Kriegleder, M., Geyer, P., Shayeghi, A., Mayor, M., Arndt, M., & Köhler, V. (2018). Tailored photocleavable peptides: fragmentation and neutralization pathways in high vacuum. Physical Chemistry Chemical Physics, 20(16), 11412–11417. https://doi.org/10.1039/c8cp01058g
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Schätti, Jonas, Rieser, Philipp Rieser, Sezer, Ugur, Richter, Georg, Geyer, Philipp, Rondina, Gustavo G., Häussinger, Daniel, Mayor, Marcel, Shayeghi, Armin, Köhler, Valentin, & Arndt, Markus. (2018). Pushing the mass limit for intact launch and photoionization of large neutral biopolymers. Communications Chemistry, 1, 93. https://doi.org/10.1038/s42004-018-0095-y
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Schwizer, Fabian, Okamoto, Yasunori, Heinisch, Tillmann, Gu, Yifan, Pellizzoni, Michela M., Lebrun, Vincent, Reuter, Raphael, Köhler, Valentin, Lewis, Jared C., & Ward, Thomas R. (2018). Artificial Metalloenzymes: Reaction Scope and Optimization Strategies. Chemical Reviews, 118(1), 142–231. https://doi.org/10.1021/acs.chemrev.7b00014
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Schatti, J., Sezer, U., Pedalino, S., Cotter, J. P., Arndt, M., Mayor, M., & Kohler, V. (2017). Tailoring the volatility and stability of oligopeptides. Journal of Mass Spectrometry, 52(8), 550–556. https://doi.org/10.1002/jms.3959
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Liu, Zhe, Lebrun, Vincent, Kitanosono, Taku, Mallin, Hendrik, Köhler, Valentin, Häussinger, Daniel, Hilvert, Donald, Kobayashi, Shu, & Ward, Thomas R. (2016). Upregulation of an Artificial Zymogen by Proteolysis. Angewandte Chemie International Edition, 55(38), 11587–11590. https://doi.org/10.1002/anie.201605010
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Okamoto, Yasunori, Köhler, Valentin, Paul, Caroline E., Hollmann, Frank, & Ward, Thomas R. (2016). Efficient In Situ Regeneration of NADH Mimics by an Artificial Metalloenzyme. ACS Catalysis, 6(6), 3553–3557. https://doi.org/10.1021/acscatal.6b00258
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Okamoto, Yasunori, Köhler, Valentin, & Ward, Thomas R. (2016). An NAD(P)H-Dependent Artificial Transfer Hydrogenase for Multienzymatic Cascades. Journal of the American Chemical Society, 138(18), 5782–5784. https://doi.org/10.1021/jacs.6b02470
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Heinisch, Tillmann, Pellizzoni, Michaela, Dürrenberger, Marc, Tinberg, Christine E., Köhler, Valentin, Häussinger, Daniel, Klehr, Juliane, Baker, David, & Ward, Thomas R. (2015). Improving the catalytic performance of an artificial metalloenzyme by computational design. Journal of the American Chemical Society, 137(32), 10414–10419. https://doi.org/10.1021/jacs.5b06622
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Köhler, Valentin, & Turner, Nicholas J. (2015). Artificial concurrent catalytic processes involving enzymes. Chemical Communications, 51(3), 450–464. https://doi.org/10.1039/c4cc07277d
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Quinto, Tommaso, Köhler, Valentin, Häussinger, Daniel, & Ward, Thomas R. (2015). Artificial metalloenzymes for the diastereoselective reduction of NAD+ to NAD2H. Organic and Biomolecular Chemistry, 13, 357–360. https://doi.org/10.1039/c4ob02071e
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Ward, Thomas R., & Koehler, Valentin. (2015). Editorial overview: Biocatalysis and biotransformation: Bio-inspired, bio-based and bio-linked catalys. Current Opinion in Chemical Biology, 25, v–vi. https://doi.org/10.1016/j.cbpa.2015.02.022
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Genz, Maika, Köhler, Valentin, Krauss, Michael, Singer, David, Hoffmann, Ralf, Ward, Thomas R., & Sträter, Norbert. (2014). An Artificial Imine Reductase based on the Ribonuclease S Scaffold. ChemCatChem, 6(3), 736–740. https://doi.org/10.1002/cctc.201300995
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Koehler, Valentin, & Ward, Thomas R. (2014). Concurrent Cross Metathesis and Enzymatic Oxidation: Enabling Off-Equilibrium Transformations. ChemCatChem, 6(8), 2191–2193. https://doi.org/10.1002/cctc.201402150
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Quinto, Tommaso, Köhler, Valentin, & Ward, Thomas R. (2014). Recent Trends in Biomimetic NADH Regeneration. Topics in Catalysis, 57(5), 321–331. https://doi.org/10.1007/s11244-013-0187-y
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Quinto, Tommaso, Schwizer, Fabian, Zimbron, Jeremy M., Morina, Albert, Köhler, Valentin, & Ward, Thomas R. (2014). Expanding the Chemical Diversity in Artificial Imine Reductases Based on the Biotin-Streptavidin Technology. ChemCatChem, 6(4), 1010–1014. https://doi.org/10.1002/cctc.201300825
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Koehler, V., Wilson, Y. M., Duerrenberger, M., Ghislieri, D., Churakova, E., Quinto, T., Knoerr, L., Haeussinger, D., Hollmann, F., Turner, N. J., & Ward, Thomas R. (2013). Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes. Nature Chemistry, 5(2), 93–99. https://doi.org/10.1038/nchem.1498
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Schwizer, Fabian, Köhler, Valentin, Dürrenberger, Marc, Knörr, Livia, & Ward, Thomas R. (2013). Genetic Optimization of the Catalytic Efficiency of Artificial Imine Reductases Based on the Biotin-Streptavidin Technology. ACS Catalysis, 3(8), 1752–1755. https://doi.org/10.1021/cs400428r
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Köhler, Valentin, Mao, Jincheng, Heinisch, Tillmann, Pordea, Anca, Sardo, Alessia, Wilson, Yvonne, Knörr, Livia, Creus, Marc, Prost, Jean-Christophe, Schirmer, Tilman, & Ward, Thomas R. (2011). OsO4⋅Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis-Dihydroxylation of Olefins. Angewandte Chemie International Edition, 50(46), 10863–10866. https://doi.org/10.1002/anie.201103632
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O’Reilly, Elaine, Köhler, Valentin, Flitsch, Sabine L., & Turner, Nicholas J. (2011). Cytochromes P450 as useful biocatalysts: addressing the limitations. Chemical Communications, 47(9), 2490–2501. https://doi.org/10.1039/c0cc03165h
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Köhler, Valentin, & Ward, Thomas R. (2010). Design of a Functional Nitric Oxide Reductase within a Myoglobin Scaffold. Chembiochem : a European journal of chemical biology, 11(8), 1049–1051. https://doi.org/10.1002/cbic.201000093
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Köhler, Valentin, Wilson, Yvonne M., Lo, Cheikh, Sardo, Alessia, & Ward, Thomas R. (2010). Protein-based hybrid catalysts-design and evolution. Current Opinion in Biotechnology, 21(6), 744–752. https://doi.org/10.1016/j.copbio.2010.09.004
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Köhler, Valentin, Mazet, Clément, Toussaint, Aurélie, Kulicke, Klaus, Häussinger, Daniel, Neuburger, Markus, Schaffner, Silvia, Kaiser, Stefan, & Pfaltz, Andreas. (2008). Chiral Boron-Bridged Bisoxazoline (Borabox) Ligands: Structures and Reactivities of Pd and Cu Complexes. Chemistry - A European Journal, 14(28), 8530–8539. https://doi.org/10.1002/chem.200800822
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Mazet, Clément, Roseblade, Stephen, Köhler, Valentin, & Pfaltz, Andreas. (2006). Kinetic Resolution of Diols and Pyridyl Alcohols by Cu(II)(borabox)-Catalyzed Acylation. Organic Letters, 8(9), 1879–1882. https://doi.org/10.1021/ol060443t
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Mazet, Clément, Köhler, Valentin, & Pfaltz, Andreas. (2005). Chiral Boron-Bridged Bisoxazolines: Readily Available Anionic Ligands for Asymmetric Catalysis. Angewandte Chemie International Edition, 44(31), 4888–4891. https://doi.org/10.1002/anie.200501111
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