Prof. Dr. Felix Mahfoud

Boeddinghaus, Jasper, Bima, Paolo, Crisanti, Luca, Keller, Dagmar I, Slankamenac, Ksenija, Christ, Michael, Schuetz, Philipp, Wiencierz, Andrea, Strebel, Ivo, Reinhardt, Julia, Vyshnevska, Iryna, Tsao, Tzu-Ying, Mahfoud, Felix, Ruggieri, Maria Pia, Steuer, Stephan, Miró, Òscar, Harjola, Veli-Pekka, Morello, Fulvio, Nazerian, Peiman, et al. (2026). PRospective evaluation of the European Society of Cardiology 0/1h-algorithm`s safety and efficacy for triage of patients with suspected myocardial infarction (PRESC1SE-MI): Rationale and design of a prospective international multicenter stepped-wedge cluster randomized controlled trial. American Heart Journal, 292. https://doi.org/10.1016/j.ahj.2025.107299

Rubini Giménez, María, Koechlin, Luca, López-Ayala, Pedro, Spagnuolo, Carlos, Boeddinghaus, Jasper, Wildi, Karin, Nestelberger, Thomas, Tkachenko, Hanna, Basic, Daniel, Kaplan, Emel, Formambuh, Jude, Bima, Paolo, Glaeser, Jonas, Crisanti, Luca, Miró, Óscar, Martín-Sánchez, F. Javier, Christ, Michael, Keller, Dagmar I., Gualandro, Danielle M., et al. (2025). Clinical implications of sex-specific upper reference limits for high-sensitivity cardiac troponin I in myocardial infarction diagnosis. Revista Espanola de Cardiologia, 78, 1064–1075. https://doi.org/10.1016/j.recesp.2025.05.001

Meier, Vincent, Aeschbacher, Stefanie, Coslovsky, Michael, Gasser, Andreas, Paladini, Rebecca E, Reichlin, Tobias, Rodondi, Nicolas, Müller, Andreas, Beer, Jürg, Conte, Giulio, Moschovitis, Giorgio, Bardoczi, Julia, Bernheim, Alain, Rigamonti, Elia, Möri, Laura, Zuern, Christine S, Mahfoud, Felix, Sticherling, Christian, Conen, David, et al. (2025). Adverse Outcomes in Patients with Atrial Fibrillation and a Pacemaker: A Cohort Study. Europace. https://doi.org/10.1093/europace/euaf275

Runge, Florine, Brügger, Jonas, Ruperti-Repilado, Francisco Javier, Subin, Behnam, Jordan, Fabian, Isenegger, Corinne, Sticherling, Christian, Kühne, Michael, Mahfoud, Felix, Tobler, Daniel, & Badertscher, Patrick. (2025). Feasibility and accuracy of wearable electrocardiogram monitoring in adult congenital heart disease. Europace, 27(10). https://doi.org/10.1093/europace/euaf247

Sticherling, Christian, Hasenfuss, Gerd, & Mahfoud, Felix. (2025). Pacing beyond rhythm – improving myocardial function by tickling the heart electrically? European Journal of Heart Failure, 27, 1850–1852. https://doi.org/10.1002/ejhf.70009

Frey, Simon M., Schneider, Igor, Otto, Ann-Sophie, Geiser, Florian, Wild, Damian, Haaf, Philip, Mahfoud, Felix, Mueller, Christian, & Zellweger, Michael J. (2025). Evaluation of the 2024 European Society of Cardiology risk-factor and calcium score-weighted clinical likelihoods as gatekeeper for patients with suspected chronic coronary syndrome referred for PET (Patent No. Suppl. 1). European Heart Journal, 46(Suppl. 1), Article Suppl. 1. https://doi.org/10.1093/eurheartj/ehaf784.307

Frey, Simon M., Schneider, Igor, Otto, Ann-Sophie, Geiser, Florian, Wild, Damian, Tsirkin, Andrew, Gyoergy, Caroline, Ruff, Peter, Haaf, Philip, Mahfoud, Felix, Mueller, Christian, & Zellweger, Michael J. (2025). Comparison of the 2024 ESC risk-factor clinical likelihood model and an artificial intelligence-based tool for ischemia detection in patients with suspected chronic coronary syndrome referred for PET (Patent No. Suppl. 1). European Heart Journal, 46(Suppl. 1), Article Suppl. 1. https://doi.org/10.1093/eurheartj/ehaf784.1692

Badertscher, Patrick, Du Fay De Lavallaz, Jeanne, Reichlin, Tobias, Roten, Laurent, Kueffer, Thomas, Jordan, Fabian, Knecht, Sven, Mahfoud, Felix, Sticherling, Christian, & Kühne, Michael. (2025). Pulsed-field ablation vs. thermal ablation for paroxysmal atrial fibrillation: A systematic review and meta-analysis of randomized controlled trials. Europace, 27. https://doi.org/10.1093/europace/euaf179

Kunz, M., Wagmann, L., Schuster, M., Götzinger, F., Link, A., & Mahfoud, F. (2025). Unveiling Cardiac Complications: A Case of Amisulpride Overdose Leading to Bradycardia, QT-Prolongation, and Torsade de Pointes Tachycardia. Therapeutic Drug Monitoring, 47(4), 462–465. https://doi.org/10.1097/ftd.0000000000001318

Subin, Behnam, Isenegger, Corinne, Mahfoud, Felix, Kühne, Michael, Knecht, Sven, Krisai, Philipp, Schaerli, Nicolas, Wahab, Merwan, Wenzel, Jan Per, Eitel, Charlotte, Heeger, Christian-Hendrik, Kuck, Karl-Heinz, Sticherling, Christian, Tilz, Roland, & Badertscher, Patrick. (2025). Comparative analysis of newest-generation variable-diameter cryoballoon with pulsed-field ablation for the treatment of atrial fibrillation: The CRYO-PULSE Study. Europace, 27. https://doi.org/10.1093/europace/euaf166

Ochoa‐Espinosa, Amanda, Genty, Lucile, Xu, Lifen, Akin, Asli, Glatz, Katharina, Decembrini, Sarah, Mueller, Christian, Neutzner, Albert, Jayachandran, Rajesh, Mahfoud, Felix, Pieters, Jean, & Kaufmann, Beat A. (2025). Coronin 1 deficiency protects from the development of autoimmune myocarditis by reducing CD4+ T cells. ESC Heart Failure, 3524–3536. https://doi.org/10.1002/ehf2.15384

Kandzari, D. E., Mahfoud, F., Townsend, R. R., Kario, K., Weber, M. A., Schmieder, R. E., Tsioufis, K., Pocock, S., Liu, M., DeBruin, V., Brar, S., & Böhm, M. (2025). Long-Term Safety and Efficacy of Renal Denervation: 24-Month Results From the SPYRAL HTN-ON MED Trial. Circulation: Cardiovascular Interventions, 18(7). https://doi.org/10.1161/circinterventions.125.015194

Thommen, Kathrin, Frey, Simon M., Kammerer, Daniel, Wild, Damian, Haaf, Philip, Mahfoud, Felix, Zellweger, Michael J, & on behalf of , the BARDOT investigators. (2025). Prognostic value of myocardial perfusion imaging in asymptomatic high-risk diabetic patients: 10-year follow-up of the prospective multicentre BARDOT trial. European Heart Journal Cardiovascular Imaging, 26(7), 1130–1139. https://doi.org/10.1093/ehjci/jeaf126

Stolte, Thorald, Sathananthan, Janarthanan, Reichl, Jakob Johannes, Boeddinghaus, Jasper, Wagener, Max, Schöpflin, Christian, Kaiser, Christoph, Leibundgut, Gregor, Mahfoud, Felix, Wood, David, Webb, John G., & Nestelberger, Thomas. (2025). Non-Invasive Hemodynamic Monitoring in Transcatheter Aortic Valve Implantation. Journal of Clinical Medicine, 14. https://doi.org/10.3390/jcm14113794

Fezzi, Simone, Giacoppo, Daniele, Fahrni, Gregor, Latib, Azeem, Alfonso, Fernando, Colombo, Antonio, Mahfoud, Felix, Scheller, Bruno, Jeger, Raban, & Cortese, Bernardo. (2025). Individual patient data meta-analysis of paclitaxel-coated balloons vs. drug-eluting stents for small-vessel coronary artery disease: the ANDROMEDA study. European Heart Journal, 46, 1586–1599. https://doi.org/10.1093/eurheartj/ehaf002

Böhm, M., Butler, J., Coats, A., Lauder, L., Mahfoud, F., Filippatos, G., Ferreira, J. P., Pocock, S. J., Brueckmann, M., Hauske, S. J., Schueler, E., Wanner, C., Verma, S., Zannad, F., Packer, M., & Anker, S. D. (2025). Empagliflozin in resistant hypertension and heart failure with preserved ejection fraction: the EMPEROR-Preserved trial. European Heart Journal, 46(14), 1304–1317. https://doi.org/10.1093/eurheartj/ehae938

Pfenniger, Anna, Stolte, Thorald, Reichl, Jakob Johannes, Leibundgut, Gregor, Wagener, Max, Kaiser, Christoph, Boeddinghaus, Jasper, Mahfoud, Felix, & Nestelberger, Thomas. (2025). Comparison of invasive and non-invasive gradients before and after TAVI and their implications on clinical outcomes. Cardiovascular Intervention and Therapeutics, 40(2), 362–377. https://doi.org/10.1007/s12928-024-01074-6

Koechlin, Luca, Boeddinghaus, Jasper, Lopez-Ayala, Pedro, Bianchi, Chiara L., Nestelberger, Thomas, Wildi, Karin, Miró, Òscar, Christ, Michael, Rentsch, Katharina, Mahfoud, Felix, & Mueller, Christian. (2025). Impact of Food and Drug Administration Regulations on the Performance of Guideline-Recommended Pathways With an Approved Point-of-Care High-Sensitivity Cardiac Troponin I Assay. Journal of the American Heart Association, 14. https://doi.org/10.1161/jaha.124.039164

Cheng, R., Alvarez Villela, M., Masoumi, A., Esposito, M. L., Baran, D. A., Rommel, K.-P., Fudim, M., Mahfoud, F., Lansky, A., Burkhoff, D., & Kapur, N. K. (2025). Charting the Course for Careers in Interventional Heart Failure: Training, Challenges, and Future Directions. Journal of the Society for Cardiovascular Angiography and Interventions, 4(3). https://doi.org/10.1016/j.jscai.2025.102569

Kuster, Gabriela M., Assmus, Birgit, & Mahfoud, Felix. (2025). Myeloperoxidase: Reviving an old ally for immunomodulation in heart failure? European Journal of Heart Failure, 27(3), 555–557. https://doi.org/10.1002/ejhf.3468

Reichl, Jakob J., Stolte, Thorald, Boeddinghaus, Jasper, Leibundgut, Gregor, Badertscher, Patrick, Sticherling, Christian, Kühne, Michael, Kaiser, Christoph, Mahfoud, Felix, & Nestelberger, Thomas. (2025). Prognostic impact of atrial fibrillation in patients undergoing transcatheter aortic valve implantation. Heart Rhythm O2, 6(3), 273–279. https://doi.org/10.1016/j.hroo.2024.12.016

Lauder, Lucas, Pfister, Otmar, & Mahfoud, Felix. (2025). Contextualizing heart rate: Visit-to-visit fluctuations and their impact on prognosis in heart failure. European Journal of Heart Failure, 27(1), 69–71. https://doi.org/10.1002/ejhf.3513

Schlaich, M. P., Mahfoud, F., Böhm, M., Narkiewicz, K., Ruilope, L., Williams, B., Mancia, G., Sharif, F., Ribichini, F., Lung, T.-H., Shetty, S., & Schmieder, R. E. (2025). Renal Denervation in Patients With Moderate to Severe Chronic Kidney Disease. 82. https://doi.org/10.1161/hypertensionaha.125.25470

Kario, K., Kandzari, D. E., Mahfoud, F., Weber, M. A., Schmieder, R. E., Tsioufis, K., Liu, M., Böhm, M., & Townsend, R. R. (2024). Renal Denervation Lowers Nighttime Blood Pressure in True Resistant Hypertension. Hypertension, 81(12), e200–e202. https://doi.org/10.1161/hypertensionaha.124.23848

Jiang, Xiongjing, Mahfoud, Felix, Li, Wei, Dong, Hui, Yu, Jing, Yu, Shuhua, Chen, Xiaoping, Wang, Peijian, Li, Zhiqiang, Lauder, Lucas, Wang, Zhifang, Ji, Zheng, Dong, Yifei, Han, Bing, Zhu, Zhiming, Chen, Yulin, Xu, Jianzhong, Zhao, Xingsheng, Fan, Weidong, et al. (2024). Efficacy and Safety of Catheter-Based Radiofrequency Renal Denervation in Chinese Patients with Uncontrolled Hypertension: The Randomized, Sham-Controlled, Multi-Center Iberis-HTN Trial. Circulation, 150(20), 1588–1598. https://doi.org/10.1161/circulationaha.124.069215

Vukadinović, Davor, Lauder, Lucas, Kandzari, David E., Bhatt, Deepak L., Kirtane, Ajay J., Edelman, Elazer R., Schmieder, Roland E., Azizi, Michel, Böhm, Michael, & Mahfoud, Felix. (2024). Effects of Catheter-Based Renal Denervation in Hypertension: A Systematic Review and Meta-Analysis. Circulation, 150(20), 1599–1611. https://doi.org/10.1161/circulationaha.124.069709

Lellig, M., Rodríguez, M., López-Baltanás, R., Hermann, J., Wollenhaupt, J., Noels, H., Zidek, W., Tepel, M., Mahfoud, F., Jankowski, J., Muñoz-Castañeda, J. R., & Jankowski, V. (2024). Pyridoxal-5′-phosphate: A cost-effective treatment candidate for hypertensive patients? Journal of Internal Medicine, 296(5), 435–448. https://doi.org/10.1111/joim.20015

Tokcan, Mert, Lauder, Lucas, Götzinger, Felix, Böhm, Michael, & Mahfoud, Felix. (2024). Arterial hypertension—clinical trials update 2024. Hypertension Research, 47(11), 3114–3125. https://doi.org/10.1038/s41440-024-01900-7

Al Ghorani, Hussam, Kulenthiran, Saarraaken, Lauder, Lucas, Recktenwald, Michael Johannes Maria, Dederer, Juliane, Kunz, Michael, Götzinger, Felix, Ewen, Sebastian, Ukena, Christian, Böhm, Michael, & Mahfoud, Felix. (2024). Ultra-long-term efficacy and safety of catheter-based renal denervation in resistant hypertension: 10-year follow-up outcomes. Clinical Research in Cardiology, 113(10), 1384–1392. https://doi.org/10.1007/s00392-024-02417-2

Gottlieb, L. A., Mahfoud, F., Stavrakis, S., Jespersen, T., & Linz, D. (2024). Autonomic Nervous System: A Therapeutic Target for Cardiac End-Organ Damage in Hypertension. Hypertension, 81(10), 2027–2037. https://doi.org/10.1161/hypertensionaha.123.19460

Lauder, Lucas, Burkard, Thilo, & Mahfoud, Felix. (2024). Balancing Affordability and Need: Should We Use Renal Denervation in Hypertension Management? Journal of the Society for Cardiovascular Angiography and Interventions, 3(10). https://doi.org/10.1016/j.jscai.2024.102248

Mahfoud, F., Azizi, M., Daemen, J., Sharp, A. S. P., Patak, A., Iglesias, J. F., Kirtane, A., Fisher, N. D. L., Scicli, A., & Lobo, M. D. (2024). Real-world experience with ultrasound renal denervation utilizing home blood pressure monitoring: the Global Paradise System registry study design. Clinical Research in Cardiology, 113(10), 1375–1383. https://doi.org/10.1007/s00392-023-02325-x

Struthoff, Helge, Lauder, Lucas, Federspiel, Jan M., Hohl, Mathias, Böhm, Michael, Tschernig, Thomas, & Mahfoud, Felix. (2024). Human nerve distribution and density around the carotid artery bifurcation. Clinical Research in Cardiology, 113(10), 1508–1513. https://doi.org/10.1007/s00392-024-02419-0

Maalouli Schaar, J., Kunz, M., Wagmann, L., Beck, O., Mahfoud, F., & Meyer, M. R. (2024). Studying drug excretion into exhaled breath aerosol – A workflow based on an impaction sampling device and LC-HRMS/MS analysis. Analytica Chimica Acta, 1323. https://doi.org/10.1016/j.aca.2024.342991

Fezzi, S., Ding, D., Mahfoud, F., Huang, J., Lansky, A. J., Tu, S., & Wijns, W. (2024). Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention? Nature Reviews Cardiology, 21(9), 652–662. https://doi.org/10.1038/s41569-024-01014-0

Götzinger, Felix, Kunz, Michael, Lauder, Lucas, Böhm, Michael, & Mahfoud, Felix. (2024). New ways of mitigating aldosterone in cardiorenal disease. European Heart Journal - Cardiovascular Pharmacotherapy, 10(6), 557–565. https://doi.org/10.1093/ehjcvp/pvae049

Böhm, Michael, de la Sierra, Alejandro, Mahfoud, Felix, Schwantke, Igor, Lauder, Lucas, Haring, Bernhard, Vinyoles, Ernest, Gorostidi, Manuel, Segura, Julián, Williams, Bryan, Staplin, Natalie, & Ruilope, Luis M. (2024). Office measurement vs. ambulatory blood pressure monitoring: associations with mortality in patients with or without diabetes. European Heart Journal, 45(31), 2851–2861. https://doi.org/10.1093/eurheartj/ehae337

Sharp, A., & Mahfoud, F. (2024). Contemporary outcomes in patients hospitalized with pulmonary embolism: what can we learn from observational data? European Heart Journal, 45(22), 1999–2001. https://doi.org/10.1093/eurheartj/ehae263

Giri, J., Mahfoud, F., Gebauer, B., Andersen, A., Friedman, O., Gandhi, R. T., Jaber, W. A., Pereira, K., & West, F. M. (2024). PEERLESS II: A Randomized Controlled Trial of Large-Bore Thrombectomy Versus Anticoagulation in Intermediate-Risk Pulmonary Embolism. Journal of the Society for Cardiovascular Angiography and Interventions, 3(6). https://doi.org/10.1016/j.jscai.2024.101982

Lauder, Lucas, Siwy, Justyna, Mavrogeorgis, Emmanouil, Keller, Felix, Kunz, Michael, Wachter, Angelika, Emrich, Insa E., Böhm, Michael, Mischak, Harald, & Mahfoud, Felix. (2024). Impact of Renal Denervation on Urinary Peptide-Based Biomarkers in Hypertension. Hypertension, 81(6), 1374–1382. https://doi.org/10.1161/hypertensionaha.124.22819

Zifkos, K., Bochenek, M. L., Gogiraju, R., Robert, S., Pedrosa, D., Kiouptsi, K., Moiko, K., Wagner, M., Mahfoud, F., Poncelet, P., Münzel, T., Ruf, W., Reinhardt, C., Panicot-Dubois, L., Dubois, C., & Schäfer, K. (2024). Endothelial PTP1B Deletion Promotes VWF Exocytosis and Venous Thromboinflammation. Circulation Research, 134(10), E93–E111. https://doi.org/10.1161/circresaha.124.324214

Townsend, R. R., Ferdinand, K. C., Kandzari, D. E., Kario, K., Mahfoud, F., Weber, M. A., Schmieder, R. E., Pocock, S., Tsioufis, K., David, S., Steigerwalt, S., Walton, A., Hopper, I., Bertolet, B., Sharif, F., Fengler, K., Fahy, M., Hettrick, D. A., Brar, S., & Böhm, M. (2024). Impact of Antihypertensive Medication Changes after Renal Denervation among Different Patient Groups: SPYRAL HTN-ON MED. Hypertension, 81(5), 1095–1105. https://doi.org/10.1161/hypertensionaha.123.22251

Al-Terki, Hani, Lauder, Lucas, Mügge, Andreas, Götzinger, Felix, Elhakim, Abdelrahman, & Mahfoud, Felix. (2024). Ultrasound-assisted endovascular thrombolysis versus large-bore thrombectomy in acute intermediate-high risk pulmonary embolism: The propensity-matched EKNARI cohort study. Catheterization and Cardiovascular Interventions, 103(5), 758–765. https://doi.org/10.1002/ccd.30998

Azizi, M., Sharp, A. S. P., Fisher, N. D. L., Weber, M. A., Lobo, M. D., Daemen, J., Lurz, P., Mahfoud, F., Schmieder, R. E., Basile, J., Bloch, M. J., Saxena, M., Wang, Y., Sanghvi, K., Jenkins, J. S., Devireddy, C., Rader, F., Gosse, P., Claude, L., et al. (2024). Patient-Level Pooled Analysis of Endovascular Ultrasound Renal Denervation or a Sham Procedure 6 Months After Medication Escalation: The RADIANCE Clinical Trial Program. Circulation, 149(10), 747–759. https://doi.org/10.1161/circulationaha.123.066941

Abdin, Amr, Lauder, Lucas, Fudim, Marat, Abraham, William T., Anker, Stefan D., Böhm, Michael, & Mahfoud, Felix. (2024). Neuromodulation interventions in the management of heart failure. European Journal of Heart Failure, 26(2), 502–510. https://doi.org/10.1002/ejhf.3147

Emrich, Insa E., Pickering, John W., Götzinger, Felix, Kramann, Rafael, Kunz, Michael, Lauder, Lucas, Papademetriou, Vasilios, Böhm, Michael, Heine, Gunnar H., & Mahfoud, Felix. (2024). Comparison of three creatinine-based equations to predict adverse outcome in a cardiovascular high-risk cohort: an investigation using the SPRINT research materials. Clinical Kidney Journal, 17(2). https://doi.org/10.1093/ckj/sfae011

Haring, B., Schumacher, H., Mancia, G., Teo, K. K., Lonn, E. M., Mahfoud, F., Schmieder, R., Mann, J. F. E., Sliwa, K., Yusuf, S., & Böhm, M. (2024). Triglyceride-glucose index, low-density lipoprotein levels, and cardiovascular outcomes in chronic stable cardiovascular disease: results from the ONTARGET and TRANSCEND trials. European Journal of Preventive Cardiology, 31(3), 311–319. https://doi.org/10.1093/eurjpc/zwad340

Lauder, Lucas, Mahfoud, Felix, & Böhm, Michael. (2024). Management of Resistant Hypertension. Annual Review of Medicine, 75, 443–457. https://doi.org/10.1146/annurev-med-050922-052605

Mahfoud, F., Wang, J., & Ray, S. (2024). The current position of β-blockers in hypertension: guidelines and clinical practice. Current Medical Research and Opinion, 40(sup1), 25–32. https://doi.org/10.1080/03007995.2024.2318003

Wintrich, J., Pavlicek, V., Brachmann, J., Bosch, R., Butter, C., Oswald, H., Rybak, K., Millenaar, D., Mahfoud, F., Böhm, M., & Ukena, C. (2024). Differences in management of telemedicine alerts on weekdays and public holidays: Results from the OptiLink heart failure trial. Journal of Telemedicine and Telecare, 30(1), 173–179. https://doi.org/10.1177/1357633x211039398

Lauder, L., Pérez Navarro, P., Götzinger, F., Ewen, S., Al Ghorani, H., Haring, B., Lepper, P. M., Kulenthiran, S., Böhm, M., Link, A., Scheller, B., & Mahfoud, F. (2023). Mechanical thrombectomy in intermediate- and high-risk acute pulmonary embolism: hemodynamic outcomes at three months. Respiratory Research, 24(1). https://doi.org/10.1186/s12931-023-02552-w

Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A., Muiesan, M. L., Tsioufis, K., Agabiti-Rosei, E., Algharably, E. A. E., Azizi, M., Benetos, A., Borghi, C., Hitij, J. B., Cifkova, R., Coca, A., Cornelissen, V., Cruickshank, J. K., Cunha, P. G., et al. (2023). 2023 ESH Guidelines for the management of arterial hypertension the Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA). Journal of Hypertension, 41(12), 1874–2071. https://doi.org/10.1097/hjh.0000000000003480

Kunz, M., Götzinger, F., Jacobs, C. M., Lauder, L., Ukena, C., Meyer, M. R., Laufs, U., Schulz, M., Böhm, M., & Mahfoud, F. (2023). Hidden sodium in effervescent-tablet dietary supplements and over-the-counter drugs: A comparative cross-sectional study. BMJ Open, 13(11). https://doi.org/10.1136/bmjopen-2023-076302

Kandzari, D. E., Townsend, R. R., Kario, K., Mahfoud, F., Weber, M. A., Schmieder, R., Pocock, S., Tsioufis, K., Konstantinidis, D., Choi, J., East, C., Lauder, L., Cohen, D., Kobayashi, T., Schmid, A., Lee, D. P., Ma, A., Weil, J., Agdirlioglu, T., et al. (2023). Safety and Efficacy of Renal Denervation in Patients Taking Antihypertensive Medications. Journal of the American College of Cardiology, 82(19), 1809–1823. https://doi.org/10.1016/j.jacc.2023.08.045

Buder, F., Mahfoud, F., Böhm, M., & Haring, B. (2023). What Is the Relevance of Low Standing Blood Pressure? American Journal of Hypertension, 36(11), 586–587. https://doi.org/10.1093/ajh/hpad074

Götzinger, F., Hohl, M., Lauder, L., Millenaar, D., Kunz, M., Meyer, M. R., Ukena, C., Lerche, C. M., Philipsen, P. A., Reichrath, J., Böhm, M., & Mahfoud, F. (2023). A randomized, placebo-controlled, trial to assess the photosensitizing, phototoxic and carcinogenic potential of hydrochlorothiazide in healthy volunteers. Journal of Hypertension, 41(11), 1853–1862. https://doi.org/10.1097/hjh.0000000000003558

Lauder, L., & Mahfoud, F. (2023). Adherence to antihypertensive medication in renal denervation trials: new studies, old problems? Hypertension Research, 46(11), 2543–2544. https://doi.org/10.1038/s41440-023-01389-6

Mahfoud, F., Kunz, M., & Götzinger, F. (2023). Renal denervation trials in hypertension – what we wait for in 2023/2024. European Journal of Internal Medicine, 117, 55–56. https://doi.org/10.1016/j.ejim.2023.09.014

Mahfoud, F., & Wijns, W. (2023). Renal Denervation for Treatment of Hypertension: From High-Level Quality Evidence to Implementation in Clinical Practice. Journal of the Society for Cardiovascular Angiography and Interventions, 2(6). https://doi.org/10.1016/j.jscai.2023.101130

Abdin, A., Komajda, M., Borer, J. S., Ford, I., Tavazzi, L., Batailler, C., Swedberg, K., Rosano, G. M. C., Mahfoud, F., & Böhm, M. (2023). Efficacy of ivabradine in heart failure patients with a high-risk profile (analysis from the SHIFT trial). ESC Heart Failure, 10(5), 2895–2902. https://doi.org/10.1002/ehf2.14455

Götzinger, F., Lauder, L., Sharp, A. S. P., Lang, I. M., Rosenkranz, S., Konstantinides, S., Edelman, E. R., Böhm, M., Jaber, W., & Mahfoud, F. (2023). Interventional therapies for pulmonary embolism. Nature Reviews Cardiology, 20(10), 670–684. https://doi.org/10.1038/s41569-023-00876-0

Mahfoud, F., & Götzinger, F. (2023). Pulmonary artery denervation – the suspense continues? EuroIntervention, 19(8), 623–624. https://doi.org/10.4244/eij-e-23-00033

Wintrich, J., Pavlicek, V., Brachmann, J., Bosch, R., Butter, C., Oswald, H., Rybak, K., Mahfoud, F., Böhm, M., & Ukena, C. (2023). Impedance-based remote monitoring in patients with heart failure and concomitant chronic kidney disease. ESC Heart Failure, 10(5), 3011–3018. https://doi.org/10.1002/ehf2.14387

Emrich, I. E., Böhm, M., & Mahfoud, F. (2023). Radial pseudoaneurysm following coronary angiography in a patient with autosomal dominant polycystic kidney disease. Clinical Research in Cardiology, 112(9), 1343–1345. https://doi.org/10.1007/s00392-023-02159-7

Götzinger, Felix, Kunz, Michael, Lauder, Lucas, Böhm, Michael, & Mahfoud, Felix. (2023). Arterial Hypertension—clinical trials update 2023. Hypertension Research, 46(9), 2159–2167. https://doi.org/10.1038/s41440-023-01359-y

Schmieder, R. E., Mahfoud, F., Mancia, G., Narkiewicz, K., Ruilope, L., Hutton, D. W. 3., Cao, K. N., Hettrick, D. A., Fahy, M., Schlaich, M. P., Böhm, M., & Pietzsch, J. B. (2023). Clinical event reductions in high-risk patients after renal denervation projected from the global SYMPLICITY registry. European Heart Journal - Quality of Care and Clinical Outcomes, 9(6), 575–582. https://doi.org/10.1093/ehjqcco/qcac056

Böhm, M., Abdin, A., Slawik, J., Mahfoud, F., Borer, J., Ford, I., Swedberg, K., Tavazzi, L., Batailler, C., & Komajda, M. (2023). Time to benefit of heart rate reduction with ivabradine in patients with heart failure and reduced ejection fraction. European Journal of Heart Failure, 25(8), 1429–1435. https://doi.org/10.1002/ejhf.2870

Böhm, M., Butler, J., Krawczyk, M., Mahfoud, F., Haring, B., Filippatos, G., Ferreira, J. P., Pocock, S. J., Brueckmann, M., Ofstad, A. P., Schüler, E., Wanner, C., Verma, S., Packer, M., & Anker, S. D. (2023). Liver tests, cardiovascular outcomes and effects of empagliflozin in patients with heart failure and preserved ejection fraction: The EMPEROR-Preserved trial. European Journal of Heart Failure, 25(8), 1375–1383. https://doi.org/10.1002/ejhf.2922

Lauder, L., Bergmann, M. W., Paitazoglou, C., Özdemir, R., Iliadis, C., Bartunek, J., Lauten, A., Keller, T., Weber, S., Sievert, H., Anker, S. D., & Mahfoud, F. (2023). Predicted impact of atrial flow regulator on survival in heart failure with reduced and preserved ejection fraction. ESC Heart Failure, 10(4), 2559–2566. https://doi.org/10.1002/ehf2.14384

Mahfoud, F., Mancia, G., Schmieder, R. E., Ruilope, L., Narkiewicz, K., Schlaich, M., Williams, B., Ribichini, F., Weil, J., Almerri, K., Sharif, F., Lauder, L., Wanten, M., Fahy, M., & Böhm, M. (2023). Outcomes Following Radiofrequency Renal Denervation According to Antihypertensive Medications: Subgroup Analysis of the Global SYMPLICITY Registry DEFINE. Hypertension, 80(8), 1759–1770. https://doi.org/10.1161/hypertensionaha.123.21283

Götzinger, F., Kunz, M., Lauder, L., Mahfoud, F., & Böhm, M. (2023). Radio frequency-based renal denervation: a story of simplicity? Future Cardiology, 19(9), 431–440. https://doi.org/10.2217/fca-2023-0059

Lauder, L., Mahfoud, F., Azizi, M., Bhatt, D. L., Ewen, S., Kario, K., Parati, G., Rossignol, P., Schlaich, M. P., Teo, K. K., Townsend, R. R., Tsioufis, C., Weber, M. A., Weber, T., & Böhm, M. (2023). Hypertension management in patients with cardiovascular comorbidities. European Heart Journal, 44(23), 2066–2077. https://doi.org/10.1093/eurheartj/ehac395

Al-Terki, H., Gotzmann, M., Mahfoud, F., Lauder, L., & Mügge, A. (2023). Urokinase versus Alteplase in Patients with Intermediate–High-Risk Pulmonary Embolism Treated with Ultrasound-Accelerated Endovascular Thrombolysis. Journal of Clinical Medicine, 12(12). https://doi.org/10.3390/jcm12124006

Götzinger, F., Wilke, T., Hardtstock, F., Krieger, J., Maywald, U., Kunz, M., Lauder, L., Schulz, M., Mahfoud, F., & Böhm, M. (2023). Association of hydrochlorothiazide treatment compared with alternative diuretics with overall and skin cancer risk: A propensity-matched cohort study. Journal of Hypertension, 41(6), 926–933. https://doi.org/10.1097/hjh.0000000000003414

Hohl, M., Lauder, L., Sevimli, Ö., Tokcan, M., Wagmann, L., Götzinger, F., Schneider, C., Hübner, U., Lehnert, U., Meyer, M. R., Böhm, M., & Mahfoud, F. (2023). Efficacy of Antihypertensive Drugs of Different Classes after Renal Denervation in Spontaneously Hypertensive Rats. Hypertension, 80(6), E90–E100. https://doi.org/10.1161/hypertensionaha.122.20756

Kirtane, A. J., Sharp, A. S. P., Mahfoud, F., Fisher, N. D. L., Schmieder, R. E., Daemen, J., Lobo, M. D., Lurz, P., Basile, J., Bloch, M. J., Weber, M. A., Saxena, M., Wang, Y., Sanghvi, K., Jenkins, J. S., Devireddy, C., Rader, F., Gosse, P., Sapoval, M., et al. (2023). Patient-Level Pooled Analysis of Ultrasound Renal Denervation in the Sham-Controlled RADIANCE II, RADIANCE-HTN SOLO, and RADIANCE-HTN TRIO Trials. JAMA Cardiology, 8(5). https://doi.org/10.1001/jamacardio.2023.0338

A. Prado, G. F., Blanco, P. J., Bulant, C. A., Ares, G. D., Mariani, J., Caixeta, A., Almeida, B. O., Garzon, S., Pinton, F. A., Barbato, E., Ribichini, F. L., Toth, G. G., Mahfoud, F., Wijns, W., Garcia-Garcia, H. M., & Lemos, P. A. (2023). Quantitative coronary three-dimensional geometry and its association with atherosclerotic disease burden and composition. Catheterization and Cardiovascular Interventions, 101(6), 1036–1044. https://doi.org/10.1002/ccd.30639

Pavlicek, V., Mahfoud, F., Bubel, K., Fries, P., Ewen, S., Böhm, M., Scheller, B., & Ukena, C. (2023). Prediction of conduction disturbances in patients undergoing transcatheter aortic valve replacement. Clinical Research in Cardiology, 112(5), 677–690. https://doi.org/10.1007/s00392-023-02160-0

Barbato, Emanuele, Azizi, Michel, Schmieder, Roland E., Lauder, Lucas, Böhm, Michael, Brouwers, Sofie, Bruno, Rosa Maria, Dudek, Dariusz, Kahan, Thomas, Kandzari, David E., Lüscher, Thomas F., Parati, Gianfranco, Pathak, Atul, Ribichini, Flavio L., Schlaich, Markus P., Sharp, Andrew S.P., Sudano, Isabella, Volpe, Massimo, Tsioufis, Costas, et al. (2023). Renal denervation in the management of hypertension in adults. A clinical consensus statement of the ESC Council on Hypertension and the European Association of Percutaneous Cardiovascular Interventions (EAPCI). European Heart Journal, 44(15), 1313–1330. https://doi.org/10.1093/eurheartj/ehad054

Barbato, Emanuele, Azizi, Michel, Schmieder, Roland E., Lauder, Lucas, Böhm, Michael, Brouwers, Sofie, Bruno, Rosa Maria, Dudek, Dariusz, Kahan, Thomas, Kandzari, David E., Lüscher, Thomas F., Parati, Gianfranco, Pathak, Atul, Ribichini, Flavio L., Schlaich, Markus P., Sharp, Andrew S.P., Sudano, Isabella, Volpe, Massimo, Tsioufis, Costas, et al. (2023). Renal denervation in the management of hypertension in adults. A clinical consensus statement of the ESC Council on Hypertension and the European Association of Percutaneous Cardiovascular Interventions (EAPCI). EuroIntervention, 18(15), 1227–1243. https://doi.org/10.4244/eij-d-22-00723

Azizi, M., Saxena, M., Wang, Y., Jenkins, J. S., Devireddy, C., Rader, F., Fisher, N. D. L., Schmieder, R. E., Mahfoud, F., Lindsey, J., Sanghvi, K., Todoran, T. M., Pacella, J., Flack, J., Daemen, J., Sharp, A. S. P., Lurz, P., Bloch, M. J., Weber, M. A., et al. (2023). Endovascular Ultrasound Renal Denervation to Treat Hypertension: The RADIANCE II Randomized Clinical Trial. Jama, 329(8), 651–661. https://doi.org/10.1001/jama.2023.0713

Al Ghorani, H., Kulenthiran, S., Recktenwald, M. J. M., Lauder, L., Kunz, M., Götzinger, F., Ewen, S., Ukena, C., Böhm, M., & Mahfoud, F. (2023). 10-Year Outcomes of Catheter-Based Renal Denervation in Patients With Resistant Hypertension. Journal of the American College of Cardiology, 81(5), 517–519. https://doi.org/10.1016/j.jacc.2022.11.038

Noubiap, J. J., Millenaar, D., Ojji, D., Wafford, Q. E., Ukena, C., Böhm, M., Sliwa, K., Huffman, M. D., & Mahfoud, F. (2023). Fifty Years of Global Cardiovascular Research in Africa: A Scientometric Analysis, 1971 to 2021. Journal of the American Heart Association, 12(3). https://doi.org/10.1161/jaha.122.027670

Sato, Y., Sharp, A. S. P., Mahfoud, F., Tunev, S., Forster, A., Ellis, M., Gomez, A., Dhingra, R., Ullman, J., Schlaich, M., Lee, D., Trudel, J., Hettrick, D. A., Kandzari, D. E., Virmani, R., & Finn, A. V. (2023). Translational value of preclinical models for renal denervation: a histological comparison of human versus porcine renal nerve anatomy. EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 18(13), e1120–e1128. https://doi.org/10.4244/eij-d-22-00369

Böhm, M., Anker, S., Mahfoud, F., Lauder, L., Filippatos, G., Ferreira, J. P., Pocock, S. J., Brueckmann, M., Saloustros, I., Schüler, E., Wanner, C., Zannad, F., Packer, M., & Butler, J. (2023). Empagliflozin, irrespective of blood pressure, improves outcomes in heart failure with preserved ejection fraction: the EMPEROR-Preserved trial. European Heart Journal, 44(5), 396–407. https://doi.org/10.1093/eurheartj/ehac693

Mahfoud, F., Kieble, M., Enners, S., Kintscher, U., Laufs, U., Böhm, M., & Schulz, M. (2023). Use of fixed-dose combination antihypertensives in Germany between 2016 and 2020: an example of guideline inertia. Clinical Research in Cardiology, 112(2), 197–202. https://doi.org/10.1007/s00392-022-01993-5

Fisher, N. D. L., & Mahfoud, F. (2023). Medication adherence in hypertension: lessons learned from renal denervation trials. European Journal of Preventive Cardiology, 30(1), 34–36. https://doi.org/10.1093/eurjpc/zwac159

Jacobs, C. M., Kunz, M., Mahfoud, F., Wagmann, L., & Meyer, M. R. (2023). Closing the gap — development of an analytical methodology using volumetric absorptive microsampling of finger prick blood followed by LC-HRMS/MS for adherence monitoring of antihypertensive drugs. Analytical and Bioanalytical Chemistry, 415(1), 167–177. https://doi.org/10.1007/s00216-022-04394-9

Kario, K., Mahfoud, F., Kandzari, D. E., Townsend, R. R., Weber, M. A., Schmieder, R. E., Tsioufis, K., Pocock, S., Brar, S., Hettrick, D. A., Fahy, M., & Böhm, M. (2023). Long-term reduction in morning and nighttime blood pressure after renal denervation: 36-month results from SPYRAL HTN-ON MED trial. Hypertension Research, 46(1), 280–288. https://doi.org/10.1038/s41440-022-01042-8

Parati, G., Goncalves, A., Soergel, D., Bruno, R. M., Caiani, E. G., Gerdts, E., Mahfoud, F., Mantovani, L., Mcmanus, R. J., Santalucia, P., & Kahan, T. (2023). New perspectives for hypertension management: progress in methodological and technological developments. European Journal of Preventive Cardiology, 30(1), 48–60. https://doi.org/10.1093/eurjpc/zwac203

Pathak, A., Rudolph, U. M., Saxena, M., Zeller, T., Müller-Ehmsen, J., Lipsic, E., Schmieder, R. E., Sievert, H., Halbach, M., Sharif, F., Parise, H., Fischell, T. A., Weber, M. A., Kandzari, D. E., & Mahfoud, F. (2023). Alcohol-mediated renal denervation in patients with hypertension in the absence of antihypertensive medications. EuroIntervention, 19(7), 602–611. https://doi.org/10.4244/eij-d-23-00088

Struthoff, H., Lauder, L., Hohl, M., Hermens, A., Tzafriri, A. R., Edelman, E. R., Kunz, M., Böhm, M., Tschernig, T., & Mahfoud, F. (2023). Histological examination of renal nerve distribution, density, and function in humans. EuroIntervention, 19(7), 612–620. https://doi.org/10.4244/eij-d-23-00264

Azizi, M., Mahfoud, F., Weber, M. A., Sharp, A. S. P., Schmieder, R. E., Lurz, P., Lobo, M. D., Fisher, N. D. L., Daemen, J., Bloch, M. J., Basile, J., Sanghvi, K., Saxena, M., Gosse, P., Jenkins, J. S., Levy, T., Persu, A., Kably, B., Claude, L., et al. (2022). Effects of Renal Denervation vs Sham in Resistant Hypertension after Medication Escalation: Prespecified Analysis at 6 Months of the RADIANCE-HTN TRIO Randomized Clinical Trial. JAMA Cardiology, 7(12), 1244–1252. https://doi.org/10.1001/jamacardio.2022.3904

Gerdts, E., Sudano, I., Brouwers, S., Borghi, C., Bruno, R. M., Ceconi, C., Cornelissen, V., Diévart, F., Ferrini, M., Kahan, T., Løchen, M.-L., Maas, A. H. E. M., Mahfoud, F., Mihailidou, A. S., Moholdt, T., Parati, G., & De Simone, G. (2022). Sex differences in arterial hypertension. European Heart Journal, 43(46), 4777–4788. https://doi.org/10.1093/eurheartj/ehac470

Schlaich, M. P., Bellet, M., Weber, M. A., Danaietash, P., Bakris, G. L., Flack, J., Dreier, R. F., Sassi-Sayadi, M., Haskell, L. P., Narkiewicz, K., Wang, J.-G., Reid, C., Katz, I., Ajani, A., Biswas, S., Esler, M., Elder, G., Roger, S., Colquhoun, D., et al. (2022). Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial. The Lancet, 400(10367), 1927–1937. https://doi.org/10.1016/s0140-6736(22)02034-7

Böhm, M., Schumacher, H., Werner, C., Teo, K. K., Lonn, E. M., Mahfoud, F., Speer, T., Mancia, G., Redon, J., Schmieder, R. E., Sliwa, K., Marx, N., Weber, M. A., Laufs, U., Williams, B., Yusuf, S., & Mann, J. F. E. (2022). Association between exercise frequency with renal and cardiovascular outcomes in diabetic and non-diabetic individuals at high cardiovascular risk. Cardiovascular Diabetology, 21(1). https://doi.org/10.1186/s12933-021-01429-w

Selejan, S.-R., Linz, D., Mauz, M., Hohl, M., Huynh, A. K. D., Speer, T., Wintrich, J., Kazakov, A., Werner, C., Mahfoud, F., & Böhm, M. (2022). Renal denervation reduces atrial remodeling in hypertensive rats with metabolic syndrome. Basic Research in Cardiology, 117(1). https://doi.org/10.1007/s00395-022-00943-6

Tzafriri, A. R., Garcia-Polite, F., Keating, J., Melidone, R., Knutson, J., Markham, P., Edelman, E. R., & Mahfoud, F. (2022). Morphometric analysis of the human common hepatic artery reveals a rich and accessible target for sympathetic liver denervation. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-05475-6

Mahfoud, F., Mancia, G., Schmieder, R. E., Ruilope, L., Narkiewicz, K., Schlaich, M., Williams, B., Ribichini, F., Weil, J., Kao, H.-L., Rodriguez-Leor, O., Noory, E., Ong, T. K., Unterseeh, T., de Araújo Gonçalves, P., Zirlik, A., Almerri, K., Sharif, F., Lauder, L., et al. (2022). Cardiovascular Risk Reduction After Renal Denervation According to Time in Therapeutic Systolic Blood Pressure Range. Journal of the American College of Cardiology, 80(20), 1871–1880. https://doi.org/10.1016/j.jacc.2022.08.802

Heradien, M., Mahfoud, F., Greyling, C., Lauder, L., van der Bijl, P., Hettrick, D. A., Stilwaney, W., Sibeko, S., Jansen van Rensburg, R., Peterson, D., Khwinani, B., Goosen, A., Saaiman, J. A., Ukena, C., Böhm, M., & Brink, P. A. (2022). Renal denervation prevents subclinical atrial fibrillation in patients with hypertensive heart disease: Randomized, sham-controlled trial. Heart Rhythm, 19(11), 1765–1773. https://doi.org/10.1016/j.hrthm.2022.06.031