Prof. Dr. med. Urs Frey

Nahum, Uri, Gorlanova, Olga, Decrue, Fabienne, Oller, Heide, Delgado-Eckert, Edgar, Böck, Andreas, Schulzke, Sven, Latzin, Philipp, Schaub, Bianca, Karvonen, Anne M, Lauener, Roger, Divaret-Chauveau, Amandine, Illi, Sabina, Roduit, Caroline, von Mutius, Erika, & Frey, Urs. (2024). Symptom trajectories in infancy for the prediction of subsequent wheeze and asthma in the BILD and PASTURE cohorts: a dynamic network analysis [Journal-article]. The Lancet Digital Health, 6(10), e718–e728. https://doi.org/10.1016/s2589-7500(24)00147-x

Gorlanova, O., Rüttimann, C., Soti, A., de Hoogh, K., Vienneau, D., Künstle, N., Da Silva Sena, C. R., Steinberg, R., Bovermann, X., Schulzke, S., Latzin, P., Röösli, M., Frey, U., & Müller, L. (2024). TOLLIP and MUC5B modulate the effect of ambient NO2 on respiratory symptoms in infancy. Chemosphere, 363. https://doi.org/10.1016/j.chemosphere.2024.142837

Künstle, Noëmi, Gorlanova, Olga, Marten, Andrea, Müller, Loretta, Sharma, Pawan, Röösli, Martin, Sinues, Pablo, Schär, Primo, Schürmann, David, Rüttimann, Céline, Da Silva Sena, Carla Rebeca, Nahum, Uri, Usemann, Jakob, Steinberg, Ruth, Yammine, Sophie, Schulzke, Sven, Latzin, Philipp, Frey, Urs, & , on behalf of the BILD study group. (2024). Differences in autophagy marker levels at birth in preterm vs. term infants [Journal-article]. Pediatric Research. https://doi.org/10.1038/s41390-024-03273-6

Salem, Y., Jakob, J., Steinberg, R., Gorlanova, O., Fuchs, O., Müller, L., Usemann, J., Frey, U., Latzin, P., & Yammine, S. (2024). Cohort Profile Update: The Bern Basel Infant Lung Development Cohort. International Journal of Epidemiology, 53(1). https://doi.org/10.1093/ije/dyad164

Awchi, Mo, Singh, Kapil Dev, Brenner, Sara Bachmann, Burckhardt, Marie-Anne, Hess, Melanie, Zeng, Jiafa, Datta, Alexandre N., Frey, Urs, Zumsteg, Urs, Szinnai, Gabor, & Sinues, Pablo. (2024). Metabolic trajectories of diabetic ketoacidosis onset described by breath analysis. Frontiers in Endocrinology, 15. https://doi.org/10.3389/fendo.2024.1360989

Sola-Martínez, R. A., Zeng, J., Awchi, M., Gisler, A., Arnold, K., Singh, K. D., Frey, U., Díaz, M. C., de Diego Puente, T., & Sinues, P. (2024). Preservation of exhaled breath samples for analysis by off-line SESI-HRMS: proof-of-concept study [Journal-article]. Journal of Breath Research, 18(1). https://doi.org/10.1088/1752-7163/ad10e1

Wyler, F., Manogaran, T., Monney, N., Salem, Y., Steinberg, R., Kentgens, A.-C., Jacobs, C., Chaya, S., Sena, C. R. d. S., Künstle, N., Gorlanova, O., Yammine, S., Gray, D. M., Frey, U., Oestreich, M.-A., & Latzin, P. (2024). Optimized algorithm for speed-of-sound-based infant sulfur hexafluoride multiple-breath washout measurements. Pediatric Pulmonology. https://doi.org/10.1002/ppul.27180

Abdel-Aziz, M. I., Thorsen, J., Hashimoto, S., Vijverberg, S. J. H., Neerincx, A. H., Brinkman, P., Van Aalderen, W., Stokholm, J., Rasmussen, M. A., Roggenbuck-Wedemeye, M., Vissing, N. H., Mortensen, M. S., Brejnrod, A. D., Fleming, L. J., Murray, C. S., Fowler, S. J., Frey, U., Bush, A., Singer, F., et al. (2023). Oropharyngeal Microbiota Clusters in Children with Asthma or Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways, and Exacerbation Risk. American Journal of Respiratory and Critical Care Medicine, 208(2), 142–154. https://doi.org/10.1164/rccm.202211-2107oc

Khaleva E, Rattu A, Brightling C, Bush A, Bossios A, Bourdin A, Chung KF, Chaudhuri R, Coleman C, Dahlén SE, Djukanovic R, Deschildre A, Fleming L, Fowler SJ, Gupta A, Hamelmann E, Hashimoto S, Hedlin G, Koppelman GH, et al. (2023). Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA). The European Respiratory Journal, 61(4). https://doi.org/10.1183/13993003.00606-2022

Awchi, M., Singh, K. D., Dill, P. E., Frey, U., Datta, A. N., & Sinues, P. (2023). Prediction of systemic free and total valproic acid by off-line analysis of exhaled breath in epileptic children and adolescents. Journal of Breath Research, 17. https://doi.org/10.1088/1752-7163/acf782

Rüttimann, C., Nissen-Kratzert, A., Mostacci, N., Künstle, N., Marten, A., Gisler, A., Bacher, K., Yammine, S., Steinberg, R., Schulzke, S., Röösli, M., Latzin, P., Hilty, M., Frey, U., & Gorlanova, O. (2023). Antibiotics in pregnancy influence nasal microbiome and respiratory morbidity in infancy. ERJ Open Research, 9. https://doi.org/10.1183/23120541.00225-2023

Gisler A., Singh K.D., Zeng J., Osswald M., Awchi M., Decrue F., Schmidt F., Sievi N.A., Chen X., Usemann J., Frey U., Kohler M., Li X., & Sinues P. (2022). An interoperability framework for multicentric breath metabolomic studies. iScience, 25(12). https://doi.org/10.1016/j.isci.2022.105557

Gisler, Amanda, Singh, Kapil Dev, Zeng, Jiafa, Osswald, Martin, Awchi, Mo, Decrue, Fabienne, Schmidt, Felix, Sievi, Noriane A., Chen, Xing, Usemann, Jakob, Frey, Urs, Kohler, Malcolm, Li, Xue, & Sinues, Pablo. (2022). An interoperability framework for multicentric breath metabolomic studies [Journal-article]. iScience, 25(12), 105557. https://doi.org/10.1016/j.isci.2022.105557

Thorsen J, Stokholm J, Rasmussen MA, Roggenbuck-Wedemeyer M, Vissing NH, Mortensen MS, Brejnrod AD, Fleming L, Bush A, Roberts G, Singer F, Frey U, Hedlin G, Nordlund B, Murray CS, Abdel-Aziz MI, Hashimoto S, van Aalderen W, Maitland-van der Zee AH, et al. (2022). Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents. Annals of the American Thoracic Society, 19(12), 2031–2043. https://doi.org/10.1513/annalsats.202110-1152oc

van Meel ER, Mensink-Bout SM, den Dekker HT, Ahluwalia TS, Annesi-Maesano I, Arshad SH, Baïz N, Barros H, von Berg A, Bisgaard H, Bønnelykke K, Carlsson CJ, Casas M, Chatzi L, Chevrier C, Dalmeijer G, Dezateux C, Duchen K, Eggesbø M, et al. (2022). Early-life respiratory tract infections and the risk of school-age lower lung function and asthma: a meta-analysis of 150 000 European children. The European Respiratory Journal, 60(4). https://doi.org/10.1183/13993003.02395-2021

Stolz D, Mkorombindo T., Schumann DM, Agusti A., Ash SY, Bafadhel M, Bai C, Chalmers JD, Criner GJ, Dharmage S.C., Franssen F.M.E., Frey U., Han M, Hansel NN, Hawkins NM, Kalhan R, Konigshoff M, Ko F.W., Parekh TM, et al. (2022). Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission. The Lancet, 400(10356), 921–972. https://doi.org/10.1016/s0140-6736(22)01273-9

Huvanandana J, Nguyen CD, Foster JM, Frey U, Reddel HK, & Thamrin C. (2022). Novel Methods of Measuring Adherence Patterns Reveal Adherence Phenotypes with Distinct Asthma Outcomes. Annals of the American Thoracic Society, 19(6), 933–942. https://doi.org/10.1513/annalsats.202106-653oc

Mariëlle W Pijnenburg, Urs Frey, Johan C De Jongste, & Sejal Saglani. (2022). Childhood asthma: pathogenesis and phenotypes. European Respiratory Journal, 59(6). https://doi.org/10.1183/13993003.00731-2021

Salem Y, Oestreich MA, Fuchs O, Usemann J, Frey U, Surbek D, Amylidi-Mohr S, Latzin P, Ramsey K, Yammine S, & Bern Basel Infant Lung Development Study Group. (2022). Are children born by cesarean delivery at higher risk for respiratory sequelae? American Journal of Obstetrics and Gynecology, 226(2), 257. https://doi.org/10.1016/j.ajog.2021.07.027

Badi Y.E., Pavel A.B., Pavlidis S., Riley J.H., Bates S., Kermani N.Z., Knowles R., Kolmert J., Wheelock C.E., Worsley S., Uddin M., Alving K., Bakke P.S., Behndig A., Caruso M., Chanez P., Fleming L.J., Fowler S.J., Frey U., et al. (2022). Mapping atopic dermatitis and anti–IL-22 response signatures to type 2–low severe neutrophilic asthma. Journal of Allergy and Clinical Immunology, 149(1), 89–101. https://doi.org/10.1016/j.jaci.2021.04.010

Decrue, F., Gorlanova, O., Salem, Y., Vienneau, D., de Hoogh, K., Gisler, A., Usemann, J., Korten, I., Nahum, U., Sinues, P., Schulzke, S., Fuchs, O., Latzin, P., Röösli, M., Frey, U., & Bild Study Group. (2022). Increased impact of air pollution on lung function in preterm versus term infants: the BILD study. Am J Respir Crit Care Med, 205(1), 99–107. https://doi.org/10.1164/rccm.202102-0272oc

Gisler, A., Eeftens, M., de Hoogh, K., Vienneau, D., Salem, Y., Yammine, S., Jakob, J., Gorlanova, O., Decrue, F., Gehrig, R., Frey, U., Latzin, P., Fuchs, O., Usemann, J., & Bild study group. (2022). Pollen exposure is associated with risk of respiratory symptoms during the first year of life. Allergy, 77(12), 3606–3616. https://doi.org/10.1111/all.15284

Gorlanova, O., Oller, H., Marten, A., Müller, L., Laine-Carmelli, J., Decrue, F., Salem, Y., Vienneau, D., de Hoogh, K., Gisler, A., Usemann, J., Korten, I., Yammine, S., Nahum, U., Künstle, N., Sinues, P., Schulzke, S., Latzin, P., Fuchs, O., et al. (2022). Ambient prenatal air pollution exposure is associated with low cord blood IL-17a in infants. Pediatric Allergy and Immunology, 34, e13902. https://doi.org/10.1111/pai.13902

Jaboyedoff M, Rakic M, Bachmann S, Berger C, Diezi M, Fuchs O, Frey U, Gervaix A, Glücksberg AS, Grotzer M, Heininger U, Kahlert CR, Kaiser D, Kopp MV, Lauener R, Neuhaus TJ, Paioni P, Posfay-Barbe K, Ramelli GP, et al. (2021). SwissPedData: Standardising hospital records for the benefit of paediatric research. Swiss Medical Weekly, 151, w30069. https://doi.org/10.4414/smw.2021.w30069

Decrue, Fabienne, Singh, Kapil Dev, Gisler, Amanda, Awchi, Mo, Zeng, Jiafa, Usemann, Jakob, Frey, Urs, & Sinues, Pablo. (2021). Combination of Exhaled Breath Analysis with Parallel Lung Function and FeNO Measurements in Infants [Doi: 10.1021/acs.analchem.1c02036]. Analytical Chemistry, 47, 15579. https://doi.org/10.1021/acs.analchem.1c02036

Decrue F, Singh KD, Gisler A, Awchi M, Zeng J., Usemann J, Frey U., & Sinues P. (2021). Combination of Exhaled Breath Analysis with Parallel Lung Function and FeNO Measurements in Infants. Analytical Chemistry, 93(47), 15579–15583. https://doi.org/10.1021/acs.analchem.1c02036

Korten I, Oestreich MA, Frey U., Moeller A, Jung A, Spinas R, Mueller-Suter D., Trachsel D, Rochat I, Spycher B, Latzin P., Casaulta C, & Ramsey K. (2021). Respiratory symptoms do not reflect functional impairment in early CF lung disease. Journal of Cystic Fibrosis, 20(6), 957–964. https://doi.org/10.1016/j.jcf.2021.04.006

de Gouveia Belinelo P, Collison AM, Murphy VE, Robinson PD, Jesson K, Hardaker K, de Queiroz Andrade E, Oldmeadow C, Martins Costa Gomes G, Sly PD, Usemann J, Appenzeller R, Gorlanova O, Fuchs O, Latzin P, Gibson PG, Frey U, & Mattes J. (2021). Maternal asthma is associated with reduced lung function in male infants in a combined analysis of the BLT and BILD cohorts. Thorax, 76(10), 996–1001. https://doi.org/10.1136/thoraxjnl-2020-215526

Rakic M, Jaboyedoff M, Bachmann S, Berger C, Diezi M, do Canto P, Forrest CB, Frey U, Fuchs O, Gervaix A, Gluecksberg AS, Grotzer M, Heininger U, Kahlert CR, Kaiser D, Kopp MV, Lauener R, Neuhaus TJ, Paioni P, et al. (2021). Clinical data for paediatric research: the Swiss approach : Proceedings of the National Symposium in Bern, Switzerland, Dec 5-6, 2019. BMC Proceedings, 15(Suppl 13), 19. https://doi.org/10.1186/s12919-021-00226-3

Winkler T., & Frey U. (2021). Airway remodeling: Shifting the trigger point for exacerbations in asthma. Journal of Allergy and Clinical Immunology, 148(3), 710–712. https://doi.org/10.1016/j.jaci.2021.07.010

Lammers A., Brinkman P., te Nijenhuis L.H., de Vries R., Dagelet Y.W.F., Duijvelaar E., Xu B., Abdel-Aziz M.I., Vijverberg S.J., Neerincx A.H., Frey U., Lutter R., Maitland-van der Zee A.H., Sterk P.J., & Sinha A. (2021). Increased day-to-day fluctuations in exhaled breath profiles after a rhinovirus challenge in asthma. Allergy: European Journal of Allergy and Clinical Immunology, 76(8), 2488–2499. https://doi.org/10.1111/all.14811

Tischer C., Karvonen A.M., Kirjavainen P.V., Flexeder C., Roponen M., Hyvarinen A., Renz H., Frey U.P., Fuchs O., & Pekkanen J. (2021). Early age exposure to moisture and mould is related to FeNO at the age of 6 years. Pediatric Allergy and Immunology, 32(6), 1226–1237. https://doi.org/10.1111/pai.13526

Fahad H Alahmadi, Andrew J Simpson, Cristina Gomez, Magnus Ericsson, John-Olof Thörngren, Craig E Wheelock, Dominic E Shaw, Louise J Fleming, Graham Roberts, John Riley, Stewart Bates, Ana R Sousa, Richard Knowles, Aruna T Bansal, Julie Corfield, Ioannis Pandis, Kai Sun, Per S Bakke, Massimo Caruso, et al. (2021). Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort. Chest, 160(1), 53–64. https://doi.org/10.1016/j.chest.2021.02.023

Santos-Valente E., Buntrock-Dopke H., Abou Taam R., Arasi S., Bakirtas A., Lozano Blasco J., Bonnelykke K., Craiu M., Cutrera R., Deschildre A., Elnazir B., Fleming L., Frey U., Gappa M., Nieto Garcia A., Skamstrup Hansen K., Hanssens L., Jahnz-Rozyk K., Jesenak M., et al. (2021). Biologicals in childhood severe asthma: The european permeable survey on the status Quo. ERJ Open Research, 7(3). https://doi.org/10.1183/23120541.00143-2021

Jaboyedoff, M., Rakic, M., Bachmann, S., Berger, C., Diezi, M., Fuchs, O., Frey, U., Gervaix, A., Glücksberg, A. S., Grotzer, M., Heininger, U., Kahlert, C. R., Kaiser, D., Kopp, M. V., Lauener, R., Neuhaus, T. J., Paioni, P., Posfay-Barbe, K., Ramelli, G. P., et al. (2021, June 21). SwissPedData: Standardising hospital records for the benefit of paediatric research [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2021.06.16.21258848

Decrue, Fabienne, Gorlanova, Olga, Salem, Yasmin, Vienneau, Danielle, de Hoogh, Kees, Gisler, Amanda, Usemann, Jakob, Korten, Insa, Nahum, Uri, Sinues, Pablo, Schulzke, Sven, Fuchs, Oliver, Latzin, Philipp, Röösli, Martin, & Frey, Urs. (2021). Increased Impact of Air Pollution on Lung Function in Preterm vs. Term Infants: The BILD Study. American Journal of Respiratory and Critical Care Medicine, not given.

de Gouveia Belinelo, Patricia, Collison, Adam M, Murphy, Vanessa E, Robinson, Paul D, Jesson, Kathryn, Hardaker, Kate, de Queiroz Andrade, Ediane, Oldmeadow, Christopher, Martins Costa Gomes, Gabriela, Sly, Peter D, Usemann, Jakob, Appenzeller, Rhea, Gorlanova, Olga, Fuchs, Oliver, Latzin, Philipp, Gibson, Peter G, Frey, Urs, & Mattes, Joerg. (2021). Maternal asthma is associated with reduced lung function in male infants in a combined analysis of the BLT and BILD cohorts. Thorax, 76.

Delgado-Eckert, Edgar, James, Anna, Meier-Girard, Delphine, Kupczyk, Maciej, Andersson, Lars I., Bossios, Apostolos, Mikus, Maria, Junya, Ono, Kenji, Izuhara, Middelveld, Roelinde, Dahlén, Barbro, Gaga, Mina, Siafakas, Nikos M., Papi, Alberto, Beghe, Bianca, Joos, Guy, Rabe, Klaus F., Sterk, Peter J., Bel, Elisabeth H., et al. (2021). Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation. The Journal of Allergy & Clinical Immunology, 148(2), 407–419. https://doi.org/10.1016/j.jaci.2020.12.652

Gisler, Amanda, Korten, Insa, de Hoogh, Kees, Vienneau, Danielle, Frey, Urs, Decrue, Fabienne, Gorlanova, Olga, Soti, Andras, Hilty, Markus, Latzin, Philipp, & Usemann, Jakob. (2021). Associations of air pollution and greenness with the nasal microbiota of healthy infants: A longitudinal study. Environmental Research, 111633.

Gisler, Amanda, Korten, Insa, de Hoogh, Kees, Vienneau, Danielle, Frey, Urs, Decrue, Fabienne, Gorlanova, Olga, Soti, Andras, Hilty, Markus, Latzin, Philipp, Usemann, Jakob, & Bild study group. (2021). Associations of air pollution and greenness with the nasal microbiota of healthy infants: A longitudinal study. Environmental Research, 202, 111633. https://doi.org/10.1016/j.envres.2021.111633

Gorlanova, Olga, Tischhauser, Eveline, Adcock, Ian M., Chung, Kian Fan, Fleming, Louise, Meier, Delphine, Sterk, Peter J., Roberts, Graham, Roberts, Amanda, Singer, Florian, Sousa, Ana R., Uddin, Mohib, Frey, Urs, & U-Biopred Study Group. (2021). Discordant use of short-acting β; 2; agonists in children and adults with severe, uncontrolled asthma from the U-BIOPRED cohort. Pediatric Pulmonology, 56(2), 338–340. https://doi.org/10.1002/ppul.25171

Jochmann A, Artusio L., Usemann J, Jamalzadeh A., Bush A., Frey U., & Fleming L.J. (2021). A 3-month period of electronic monitoring can provide important information to the healthcare team to assess adherence and improve asthma control. ERJ Open Research, 7(3). https://doi.org/10.1183/23120541.00726-2020

Korten, Insa, Oestreich, Marc-Alexander, Frey, Urs, Moeller, Alexander, Jung, Andreas, Spinas, Renate, Müller-Suter, Dominik, Trachsel, Daniel, Rochat, Isabelle, Spycher, Ben, Latzin, Philipp, Casaulta, Carmen, & Ramsey, Kathryn. (2021). Respiratory symptoms do not reflect functional impairment in early CF lung disease. Journal of Cystic Fibrosis, 1569.

Pijnenburg, Mariëlle W, Frey, Urs, De Jongste, Johan C, & Saglani, Sejal. (2021). Childhood asthma pathogenesis and phenotypes. ERj, 2100731.

Salem, Yasmin, Oestreich, Marc-Alexander, Fuchs, Oliver, Usemann, Jakob, Frey, Urs, Surbek, Daniel, Amylidi-Mohr, Sofia, Latzin, Philipp, Ramsey, Kathryn, & Yammine, Sophie. (2021). Are children born by cesarean delivery at higher risk for respiratory sequelae? American Journal of Obstetrics and Gynacology, not known.

Singh KD, Osswald M, Ziesenitz VC, Awchi M, Usemann J, Imbach LL, Kohler M, García-Gómez D, van den Anker J, Frey U, Datta AN, & Sinues P. (2021). Personalised therapeutic management of epileptic patients guided by pathway-driven breath metabolomics. Communications Medicine, 1, 21. https://doi.org/10.1038/s43856-021-00021-3

Soti, A. L., Usemann, J., Schaub, B., Frey, U., Latzin, P., Fuchs, O., & Bild Study Group. (2021). Can biomarkers in umbilical cord blood predict atopic disease at school age? Pediatr Res, 89(2), 389–392. https://doi.org/10.1038/s41390-019-0686-z

Lawrence AK, Selter L, & Frey U. (2020). SPHN - The Swiss personalized health network initiative. Studies in Health Technology and Informatics, 270, 1156–1160. https://doi.org/10.3233/SHTI200344

Decrue F, Gorlanova O, Usemann J, & Frey U. (2020). Correction to: Lung functional development and asthma trajectories. Seminars in Immunopathology, 42(2), 227. https://doi.org/10.1007/s00281-020-00795-z

Abdel-Aziz, Mahmoud I., Brinkman, Paul, Vijverberg, Susanne J. H., Neerincx, Anne H., de Vries, Rianne, Dagelet, Yennece W. F., Riley, John H., Hashimoto, Simone, Montuschi, Paolo, Chung, Kian Fan, Djukanovic, Ratko, Fleming, Louise J., Murray, Clare S., Frey, Urs, Bush, Andrew, Singer, Florian, Hedlin, Gunilla, Roberts, Graham, Dahlén, Sven-Erik, et al. (2020). eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy. Journal of Allergy and Clinical Immunology, 146(5), 1045–1055. https://doi.org/10.1016/j.jaci.2020.05.038

Abdel-Aziz, Mahmoud I., de Vries, Rianne, Lammers, Ariana, Xu, Binbin, Neerincx, Anne H., Vijverberg, Susanne J. H., Dagelet, Yennece W. F., Kraneveld, Aletta D., Frey, Urs, Lutter, René, Sterk, Peter J., Maitland-van der Zee, Anke H., & Sinha, Anirban. (2020). Cross-sectional biomarker comparisons in asthma monitoring using a longitudinal design: The eNose premise. Allergy, 75(10), 2690–2693. https://doi.org/10.1111/all.14354

Cruz AA, Riley JH, Bansal AT, Ponte EV, Souza-Machado A, Almeida PCA, Biao-Lima V, Davis M, Bates S, Adcock IM, Sterk PJ, Chung KF, ProAR Study Group., & U-BIOPRED Study Groups. (2020). Asthma similarities across ProAR (Brazil) and U-BIOPRED (Europe) adult cohorts of contrasting locations, ethnicity and socioeconomic status. Respiratory Medicine, 161, 105817. https://doi.org/10.1016/j.rmed.2019.105817

Decrue, Fabienne, Gorlanova, Olga, Usemann, Jakob, & Frey, Urs. (2020). Lung functional development and asthma trajectories. Seminars in Immunopathology, 42(1), 17–27. https://doi.org/10.1007/s00281-020-00784-2

Decrue, Fabienne, Gorlanova, Olga, Usemann, Jakob, & Frey, Urs. (2020). Correction to: Lung functional development and asthma trajectories. Seminars in Immunopathology, 42(2), 227. https://doi.org/10.1007/s00281-020-00795-z

Decrue, Fabienne, Gorlanova, Olga, Usemann, Jakob, & Frey, Urs. (2020). Lung functional development and asthma trajectories. Seminars in Immunopathology, 42.

Gisler, Amanda, Lan, Jiayi, Singh, Kapil Dev, Usemann, Jakob, Frey, Urs, Zenobi, Renato, & Sinues, Pablo (. (2020). 01.10.2020), Real-time breath analysis of exhaled compounds upon peppermint oil ingestion by secondary electrospray ionization-high resolution mass spectrometry: technical aspects,. In Journal of Breath Research, , 14(4), 046001.

Gisler, Amanda, Lan, Jiayi, Singh, Kapil Dev, Usemann, Jakob, Frey, Urs, Zenobi, Renato, & Sinues, Pablo. (2020). Real-time breath analysis of exhaled compounds upon peppermint oil ingestion by secondary electrospray ionization-high resolution mass spectrometry: technical aspects. Journal of Breath Research, 14(4), 46001. https://doi.org/10.1088/1752-7163/ab9f8b

Gorlanova, Olga, Appenzeller, Rhea, Mahmoud, Yasmin S., Ramsey, Kathryn A., Usemann, Jakob, Decrue, Fabienne, Kuehni, Claudia E., Röösli, Martin, Latzin, Philipp, Fuchs, Oliver, Soti, Andras, Frey, Urs, & On behalf of the BILD Study Group. (2020). Effect of breastfeeding duration on lung function, respiratory symptoms and allergic diseases in school‐age children. Paed Pulm, 55.

Gorlanova, Olga, Appenzeller, Rhea, Mahmoud, Yasmin S., Ramsey, Kathryn A., Usemann, Jakob, Decrue, Fabienne, Kuehni, Claudia E., Röösli, Martin, Latzin, Philipp, Fuchs, Oliver, Soti, Andras, Frey, Urs, & On Behalf Of The Bild Study Group. (2020). Effect of breastfeeding duration on lung function, respiratory symptoms and allergic diseases in school-age children. Pediatric Pulmonology, 55(6), 1448–1455. https://doi.org/10.1002/ppul.24733

Holguin, Fernando, Cardet, Juan Carlos, Chung, Kian Fan, Diver, Sarah, Ferreira, Diogenes S., Fitzpatrick, Anne, Gaga, Mina, Kellermeyer, Liz, Khurana, Sandhya, Knight, Shandra, McDonald, Vanessa M., Morgan, Rebecca L., Ortega, Victor E., Rigau, David, Subbarao, Padmaja, Tonia, Thomy, Adcock, Ian M., Bleecker, Eugene R., Brightling, Chris, et al. (2020). Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline. European Respiratory Journal, 55(1), 1900588. https://doi.org/10.1183/13993003.00588-2019

Jochmann, Anja, Artusio, Luca, Sharifian, Hoda, Jamalzadeh, Angela, Fleming, Louise J., Bush, Andrew, Frey, Urs, & Delgado-Eckert, Edgar. (2020). Fluctuation-based clustering reveals phenotypes of patients with different asthma severity. ERJ Open Research, 6(2), 00007–02019. https://doi.org/10.1183/23120541.00007-2019

Roberts, Graham, Fontanella, Sara, Selby, Anna, Howard, Rebecca, Filippi, Sarah, Hedlin, Gunilla, Nordlund, Bjorn, Howarth, Peter, Hashimoto, Simone, Brinkman, Peter, Fleming, Louise J., Murray, Clare, Bush, Andrew, Frey, Urs, Singer, Florian, Schoos, Ann-Marie Malby, van Aalderen, Wim, Djukanovic, Ratko, Chung, K. Fan, et al. (2020). Connectivity patterns between multiple allergen specific IgE antibodies and their association with severe asthma. The Journal of Allergy & Clinical Immunology, 146(4), 821–830. https://doi.org/10.1016/j.jaci.2020.02.031

Sinha, Anirban, Lutter, René, Dekker, Tamara, Dierdorp, Barbara, Sterk, Peter J., Delgado-Eckert, Edgar, & Frey, Urs. (2020). Can Measurements of Inflammatory Biomarkers be Used to Spot Respiratory Viral Infections? Viruses, 12(10), 1175. https://doi.org/10.3390/v12101175

Brick T, Hose A, Wawretzka K, von Mutius E, Roduit C, Lauener R, Riedler J, Karvonen AM, Pekkanen J, Divaret-Chauveau A, Dalphin JC, Ege MJ, & PASTURE study group. (2019). Parents know it best: Prediction of asthma and lung function by parental perception of early wheezing episodes. Pediatric Allergy and Immunology, 30(8), 795–802. https://doi.org/10.1111/pai.13118

Östling J, van Geest M, Schofield JPR, Jevnikar Z, Wilson S, Ward J, Lutter R, Shaw DE, Bakke PS, Caruso M, Dahlen SE, Fowler SJ, Horváth I, Krug N, Montuschi P, Sanak M, Sandström T, Sun K, Pandis I, et al. (2019). IL-17–high asthma with features of a psoriasis immunophenotype. Journal of Allergy and Clinical Immunology, 144(5), 1198–1213. https://doi.org/10.1016/j.jaci.2019.03.027

Jost K, Datta AN, Frey UP, Suki B, & Schulzke SM. (2019). Heart rate fluctuation after birth predicts subsequent cardiorespiratory stability in preterm infants. Pediatric Research, 86(3), 348–354. https://doi.org/10.1038/s41390-019-0424-6

Atto B., Eapen M.S., Sharma P., Frey U., Ammit A.J., Markos J., Chia C., Larby J., Haug G., Weber H.C., Mabeza G., Tristram S., Myers S., Geraghty D.P., Flanagan K.L., Hansbro P.M., & Sohal S.S. (2019). New therapeutic targets for the prevention of infectious acute exacerbations of COPD: Role of epithelial adhesion molecules and inflammatory pathways. Clinical Science, 133(14), 1663–1703. https://doi.org/10.1042/cs20181009

Perotin JM, Schofield JPR, Wilson SJ, Ward J, Brandsma J, Strazzeri F, Bansal A, Yang X, Rowe A, Corfield J, Lutter R, Shaw DE, Bakke PS, Caruso M, Dahlén B, Fowler SJ, Horváth I, Howarth P, Krug N, et al. (2019). Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux (Patent No. 6). 53(6), Article 6. https://doi.org/10.1183/13993003.00453-2019

Korten I, Ramsey K, Mika M, Usemann J, Frey U, Hilty M, & Latzin P. (2019). Nasal microbiota and respiratory tract infections: The role of viral detection (Patent No. 7). 199(7), Article 7. https://doi.org/10.1164/rccm.201710-2020le

Jevnikar Z, Östling J, Ax E, Calvén J, Thörn K, Israelsson E, Öberg L, Singhania A, Lau LCK, Wilson SJ, Ward JA, Chauhan A, Sousa AR, De Meulder B, Loza MJ, Baribaud F, Sterk PJ, Chung KF, Sun K, et al. (2019). Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation. Journal of Allergy and Clinical Immunology, 143(2), 577–590. https://doi.org/10.1016/j.jaci.2018.05.026

Simpson AJ, Hekking PP, Shaw DE, Fleming LJ, Roberts G, Riley JH, Bates S, Sousa AR, Bansal AT, Pandis I, Sun K, Bakke PS, Caruso M, Dahlén B, Dahlén SE, Horvath I, Krug N, Montuschi P, Sandstrom T, et al. (2019). Treatable traits in the European U-BIOPRED adult asthma cohorts (Patent No. 2). 74(2), Article 2. https://doi.org/10.1111/all.13629

Frey, Urs, & Usemann, Jakob. (2019). Addressing the complexity of prenatal and postnatal environmental exposures affecting childhood lung function. The Lancet Planetary Health, 3(2), e51–e52. https://doi.org/10.1016/s2542-5196(19)30011-7

Frey, Urs, & Usemann, Jakob (01.02. (2019). Addressing the complexity of prenatal and postnatal environmental exposures affecting childhood lung function,. The Lancet, 3.

Köchli, Sabrina, Endes, Katharina, Bartenstein, Tim, Usemann, Jakob, Schmidt-Trucksäss, Arno, Frey, Urs, Zahner, Lukas, & Hanssen, Henner. (2019). Lung function, obesity and physical fitness in young children: The EXAMIN YOUTH study. Respiratory Medicine, 159, 105813. https://doi.org/10.1016/j.rmed.2019.105813

Korten I, Kieninger E, Yammine S, Cangiano G, Nyilas S, Anagnostopoulou P, Singer F, Kuehni CE, Regamey N, Frey U, Casaulta C, Spycher BD, Latzin P, SCILD, & BILD study group. (2019). Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth. Journal of Cystic Fibrosis, 18(1), 118–126. https://doi.org/10.1016/j.jcf.2018.07.002

Korten, Insa, Kieninger, Elisabeth, Yammine, Sophie, Cangiano, Giulia, Nyilas, Sylvia, Anagnostopoulou, Pinelopi, Singer, Florian, Kuehni, Claudia E., Regamey, Nicolas, Frey, Urs, Casaulta, Carmen, Spycher, Ben D., & Latzin, Philipp. (2019). Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth,. In Journal of Cystic Fibrosis, 18.

Korten, Insa, Ramsey, Kathryn, Mika, Moana, Usemann, Jakob, Frey, Urs, Hilty, Markus, & Latzin, Philipp. (2019). Nasal Microbiota and Respiratory Tract Infections: The Role of Viral Detection,. American Journal of Respiratory and Critical Care Medicine, 199.

Meier-Girard, Delphine, Delgado-Eckert, Edgar, Schaffner, Emmanuel, Schindler, Christian, Künzli, Nino, Adam, Martin, Pichot, Vincent, Kronenberg, Florian, Imboden, Medea, Frey, Urs, & Probst-Hensch, Nicole. (2019). Association of long-term exposure to traffic-related PM; 10; with heart rate variability and heart rate dynamics in healthy subjects. Environment international, 125, 107–116. https://doi.org/10.1016/j.envint.2019.01.031

Singh, Kapil Dev, Tancev, Georgi, Decrue, Fabienne, Usemann, Jakob, Appenzeller, Rhea, Barreiro, Pedro, Jaumà, Gabriel, Macia Santiago, Miriam, Vidal de Miguel, Guillermo, Frey, Urs, & Sinues, Pablo. (2019). Standardization procedures for real-time breath analysis by secondary electrospray ionization high-resolution mass spectrometry. Analytical and Bioanalytical Chemistry, 411.

Singh, Kapil Dev, Tancev, Georgi, Decrue, Fabienne, Usemann, Jakob, Appenzeller, Rhea, Barreiro, Pedro, Jaumà, Gabriel, Macia Santiago, Miriam, Vidal de Miguel, Guillermo, Frey, Urs, & Sinues, Pablo. (2019). Standardization procedures for real-time breath analysis by secondary electrospray ionization high-resolution mass spectrometry. Analytical and Bioanalytical Chemistry, 411(19), 4883–4898. https://doi.org/10.1007/s00216-019-01764-8

Sinha, Anirban, Lutter, René, Xu, Binbin, Dekker, Tamara, Dierdorp, Barbara, Sterk, Peter J., Frey, Urs, & Eckert, Edgar Delgado. (2019). Loss of adaptive capacity in asthmatic patients revealed by biomarker fluctuation dynamics after rhinovirus challenge. eLife, 8, e47969. https://doi.org/10.7554/elife.47969

Usemann, Jakob, Decrue, Fabienne, Korten, Insa, Proietti, Elena, Gorlanova, Olga, Vienneau, Danielle, Fuchs, Oliver, Latzin, Philipp, Röösli, Martin, & Frey, Urs. (2019). , Exposure to moderate air pollution and associations with lung function at school-age: A birth cohort study. Environment International, 126, 682–689.

Usemann, Jakob, Decrue, Fabienne, Korten, Insa, Proietti, Elena, Gorlanova, Olga, Vienneau, Danielle, Fuchs, Oliver, Latzin, Philipp, Röösli, Martin, Frey, Urs, & Bild study group. (2019). Exposure to moderate air pollution and associations with lung function at school-age: A birth cohort study. Environment International, 126, 682–689. https://doi.org/10.1016/j.envint.2018.12.019

Usemann, Jakob, Suter, Andrea, Zannin, Emanuela, Proietti, Elena, Fouzas, Sotirios, Schulzke, Sven, Latzin, Philipp, Frey, Urs, & Bild study group. (2019). Variability of Tidal Breathing Parameters in Preterm Infants and Associations with Respiratory Morbidity during Infancy: A Cohort Study. Journal of Pediatrics, 205, 61–69. https://doi.org/10.1016/j.jpeds.2018.10.002

Neumann RP, Hilty M, Xu B, Usemann J, Korten I, Mika M, Müller L, Latzin P, & Frey U. (2018). Nasal microbiota and symptom persistence in acute respiratory tract infections in infants. ERJ open research, 4(4). https://doi.org/10.1183/23120541.00066-2018

Hekking PP, Loza MJ, Pavlidis S, de Meulder B, Lefaudeux D, Baribaud F, Auffray C, Wagener AH, Brinkman P Ir, Lutter R Ir, Bansal AT, Sousa AR, Bates SA, Pandis Y, Fleming LJ, Shaw DE, Fowler SJ, Guo Y, Meiser A, et al. (2018). Pathway discovery using transcriptomic profiles in adult-onset severe asthma. The Journal of Allergy and Clinical Immunology, 141(4), 1280–1290. https://doi.org/10.1016/j.jaci.2017.06.037

Zimmermann K, Cignacco E, Engberg S, Ramelet AS, von der Weid N, Eskola K, Bergstraesser E, PELICAN Consortium, Ansari M, Aebi C, Baer R, Popovic MB, Bernet V, Brazzola P, Bucher HU, Buder R, Cagnazzo S, Dinten B, Dorsaz A, et al. (2018). Patterns of paediatric end-of-life care: a chart review across different care settings in Switzerland. BMC pediatrics, 18(1), 67. https://doi.org/10.1186/s12887-018-1021-2

Cantuaria, Manuella Lech, Usemann, Jakob, Proietti, Elena, Blanes-Vidal, Victoria, Dick, Bernhard, Flück, Christa E., Rüedi, Simone, Héritier, Harris, Wunderli, Jean-Marc, Latzin, Philipp, Frey, Urs, Röösli, Martin, & Vienneau, Danielle. (2018). Glucocorticoid metabolites in newborns: A marker for traffic noise related stress? Environment International, 117, 319–326.

Cantuaria, Manuella Lech, Usemann, Jakob, Proietti, Elena, Blanes-Vidal, Victoria, Dick, Bernhard, Flück, Christa E., Rüedi, Simone, Héritier, Harris, Wunderli, Jean-Marc, Latzin, Philipp, Frey, Urs, Röösli, Martin, Vienneau, Danielle, & Bild study group. (2018). Glucocorticoid metabolites in newborns : a marker for traffic noise related stress? Environment international, 117, 319–326. https://doi.org/10.1016/j.envint.2018.05.002

Delgado-Eckert, Edgar, Fuchs, Oliver, Kumar, Nitin, Pekkanen, Juha, Dalphin, Jean-Charles, Riedler, Josef, Lauener, Roger, Kabesch, Michael, Kupczyk, Maciej, Dahlen, Sven-Eric, Mutius, Erika von, Frey, Urs, Pasture Study Group, & Bioair Study groups. (2018). Functional phenotypes determined by fluctuation-based clustering of lung function measurements in healthy and asthmatic cohort participants. Thorax, 73(2), 107–115. https://doi.org/10.1136/thoraxjnl-2016-209919

Korten, Insa, Kieninger, Elisabeth, Klenja, Shkipe, Mack, Ines, Schläpfer, Njima, Barbani, Maria Teresa, Regamey, Nicolas, Kuehni, Claudia E, Hilty, Markus, Frey, Urs, Gorgievski, Meri, Casaulta, Carmen, & Latzin, Philipp. (2018). , Respiratory viruses in healthy infants and infants with cystic fibrosis: a prospective cohort study,. In Thorax, 73.

Korten, Insa, Kieninger, Elisabeth, Klenja, Shkipe, Mack, Ines, Schläpfer, Njima, Barbani, Maria Teresa, Regamey, Nicolas, Kuehni, Claudia E., Hilty, Markus, Frey, Urs, Gorgievski, Meri, Casaulta, Carmen, Latzin, Philipp, Scild, & Bild study groups. (2018). Respiratory viruses in healthy infants and infants with cystic fibrosis: a prospective cohort study. Thorax, 73(1), 13–20. https://doi.org/10.1136/thoraxjnl-2016-209553

Korten, Insa, Liechti, Margot, Singer, Florian, Hafen, Gaudenz, Rochat, Isabelle, Anagnostopoulou, Pinelopi, Müller-Suter, Dominik, Usemann, Jakob, Moeller, Alexander, Frey, Urs, Latzin, Philipp, & Casaulta, Carmen. (2018). Lower exhaled nitric oxide in infants with Cystic Fibrosis compared to healthy controls. Journal of Cystic Fibrosis, 17(1), 105–108. https://doi.org/10.1016/j.jcf.2017.05.005

Lupatsch JE, Kreis C, Korten I, Latzin P, Frey U, Kuehni CE, & Spycher BD. (2018). Neighbourhood child population density as a proxy measure for exposure to respiratory infections in the first year of life: A validation study. PloS One, 13(9), e0203743. https://doi.org/10.1371/journal.pone.0203743

Lupatsch, Judith E., Kreis, Christian, Korten, Insa, Latzin, Philipp, Frey, Urs, Kuehni, Claudia E., & Spycher, Ben D. (2018). Neighbourhood child population density as a proxy measure for exposure to respiratory infections in the first year of life: A validation study. Plos One, 13.

Lurà, Marco Patrick, Gorlanova, Olga, Müller, Loretta, Proietti, Elena, Vienneau, Danielle, Reppucci, Diana, Pavlovic, Rodoljub, Dahinden, Clemens, Röösli, Martin, Latzin, Philipp, & Frey, Urs. (2018). Response of cord blood cells to environmental, hereditary and perinatal factors : a prospective birth cohort study. PLoS ONE, 13(7), e0200236. https://doi.org/10.1371/journal.pone.0200236

Neumann, Roland P., Hilty, Markus, Xu, Binbin, Usemann, Jakob, Korten, Insa, Mika, Moana, Müller, Loretta, Latzin, Philipp, & Frey, Urs. (2018). Nasal microbiota and symptom persistence in acute respiratory tract infections in infants. ERJ Open Research, 4.

Pavord, Ian D., Beasley, Richard, Agusti, Alvar, Anderson, Gary P., Bel, Elisabeth, Brusselle, Guy, Cullinan, Paul, Custovic, Adnan, Ducharme, Francine M., Fahy, John V., Frey, Urs, Gibson, Peter, Heaney, Liam G., Holt, Patrick G., Humbert, Marc, Lloyd, Clare M., Marks, Guy, Martinez, Fernando D., Sly, Peter D., et al. (2018). After asthma: redefining airways diseases. The Lancet, 391(10118), 350–400. https://doi.org/10.1016/s0140-6736(17)30879-6

Pedersen, Eva S. L., de Jong, Carmen C. M., Ardura-Garcia, Cristina, Barben, Juerg, Casaulta, Carmen, Frey, Urs, Jochmann, Anja, Latzin, Philipp, Moeller, Alexander, Regamey, Nicolas, Singer, Florian, Spycher, Ben, Sutter, Oliver, Goutaki, Myrofora, & Kuehni, Claudia E. (2018). The Swiss Paediatric Airway Cohort (SPAC). ERJ Open Research, 4(4), 00050–02018. https://doi.org/10.1183/23120541.00050-2018

Singh, Kapil Dev, Del Miguel, Guillermo Vidal, Gaugg, Martin Thomas, Ibañez, Alfredo J., Zenobi, Renato, Kohler, Malcolm, Frey, Urs, & Sinues, Pablo M.-L. (2018). Translating secondary electrospray ionization-high-resolution mass spectrometry to the clinical environment. Journal of Breath Research, 12(2), 27113. https://doi.org/10.1088/1752-7163/aa9ee3