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Prof. Dr. Dr. Matthias Briel

Department of Clinical Research
Profiles & Affiliations

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Peer-Reviewed Publication Types

Hirt, Julian, Ewald, Hannah, Briel, Matthias, & Schandelmaier, Stefan. (2024). Searching a methods topic: practical challenges and implications for search design. Journal of Clinical Epidemiology, 166. https://doi.org/10.1016/j.jclinepi.2023.10.017
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Puljak, Livia, Bala, Małgorzata M., Zając, Joanna, Meštrović, Tomislav, Buttigieg, Sandra, Yanakoulia, Mary, Briel, Matthias, Lunny, Carole, Lesniak, Wiktoria, Poklepović Peričić, Tina, Alonso-Coello, Pablo, Clarke, Mike, Djulbegovic, Benjamin, Gartlehner, Gerald, Giannakou, Konstantinos, Glenny, Anne-Marie, Glenton, Claire, Guyatt, Gordon, Hemkens, Lars G., et al. (2024). Methods proposed for monitoring the implementation of evidence-based research: a cross-sectional study [Journal-article]. Journal of Clinical Epidemiology, 168, 111247. https://doi.org/10.1016/j.jclinepi.2024.111247
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Wang, Y., Parpia, S., Couban, R., Wang, Q., Armijo-Olivo, S., Bassler, D., Briel, M., Brignardello-Petersen, R., Gluud, L. L., Keitz, S. A., Letelier, L. M., Ravaud, P., Schulz, K. F., Siemieniuk, R. A. C., Zeraatkar, D., & Guyatt, G. H. (2024). Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors. Journal of Clinical Epidemiology, 165. https://doi.org/10.1016/j.jclinepi.2023.11.001
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Klatte, K., Sluka, C., Gloy, V., Heravi, A. T., Schönenberger, C., Jones, N., Brunnschweiler, E., Pauli-Magnus, C., & Briel, M. (2023). Towards full clinical trial registration and results publication: longitudinal meta-research study in Northwestern and Central Switzerland. BMC Medical Research Methodology, 23(1). https://doi.org/10.1186/s12874-023-01840-9
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Troseid M., Arribas J.R., Assoumou L., Holten A.R., Poissy J., Terzic V., Mazzaferri F., Bano J.R., Eustace J., Hites M., Joannidis M., Paiva J.-A., Reuter J., Puntmann I., Patrick-Brown T.D.J.H., Westerheim E., Nezvalova-Henriksen K., Beniguel L., Dahl T.B., et al. (2023). Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial. Critical Care, 27(1). https://doi.org/10.1186/s13054-022-04205-8
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Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A, Amico, Patrizia, Stoeckle, Marcel P, Eichenberger, Anna L, Hasse, Barbara, Braun, Dominique L, Schuurmans, Macé M, Müller, Thomas F, Tamm, Michael, Audigé, Annette, Mueller, Nicolas J, Rauch, Andri, Günthard, Huldrych F, Koller, Michael T, Trkola, Alexandra, Epp, Selina, Amstutz, Alain, et al. (2023). Antibody Response After the Third SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients and People Living With HIV (COVERALL-2) [Journal-article]. Open Forum Infectious Diseases, 10(11). https://doi.org/10.1093/ofid/ofad536
Yao, M., Wang, Y., Busse, J. W., Briel, M., Mei, F., Li, G., Zou, K., Li, L., & Sun, X. (2023). Evaluating the impact of including non-randomised studies of interventions in meta-analysis of randomised controlled trials: A protocol for a meta-epidemiological study. BMJ Open, 13(7). https://doi.org/10.1136/bmjopen-2023-073232
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Amstutz, Alain, Speich, Benjamin, Mentré, France, Rueegg, Corina Silvia, Belhadi, Drifa, Assoumou, Lambert, Burdet, Charles, Murthy, Srinivas, Dodd, Lori Elizabeth, Wang, Yeming, Tikkinen, Kari A O, Ader, Florence, Hites, Maya, Bouscambert, Maude, Trabaud, Mary Anne, Fralick, Mike, Lee, Todd C, Pinto, Ruxandra, Barratt-Due, Andreas, et al. (2023). Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials. The Lancet Respiratory Medicine, 11(5), 453–464. https://doi.org/10.1016/s2213-2600(22)00528-8
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Blum, Claudine A., Roethlisberger, Eva A., Cesana-Nigro, Nicole, Winzeler, Bettina, Rodondi, Nicolas, Blum, Manuel R., Briel, Matthias, Mueller, Beat, Christ-Crain, Mirjam, & Schuetz, Philipp. (2023). Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial. BMC Pulmonary Medicine, 23. https://doi.org/10.1186/s12890-023-02794-w
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Ebrahimi, Fahim, Hirt, Julian, Schönenberger, Christof, Ewald, Hannah, Briel, Matthias, Janiaud, Perrine, & Hemkens, Lars G. (2023). Colchicine for the secondary prevention of cardiovascular events. Cochrane Database of Systematic Reviews, 2023(8). https://doi.org/10.1002/14651858.cd014808
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Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé M., Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas J., Rauch, Andri, Günthard, Huldrych F., Koller, Michael T., Trkola, Alexandra, Epp, Selina, Amstutz, Alain, et al. (2023). Antibody Response After Third Vaccination With mRNA-1273 or BNT162b2: Extension of a Randomized Controlled SARS-CoV-2 Noninferiority Vaccine Trial in Patients With Different Levels of Immunosuppression (COVERALL-2). Open Forum Infectious Diseases, 10. https://doi.org/10.1093/ofid/ofad150
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Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé M., Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas J., Rauch, Andri, Günthard, Huldrych F., Koller, Michael T., Trkola, Alexandra, Epp, Selina, Amstutz, Alain, et al. (2023). Antibody Response After the Third SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients and People Living With HIV (COVERALL-2). Open Forum Infectious Diseases, 10. https://doi.org/10.1093/ofid/ofad536
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Guyatt, Gordon, Zhao, Yunli, Mayer, Martin, Briel, Matthias, Mustafa, Reem, Izcovich, Ariel, Hultcrantz, Monica, Iorio, Alfonso, Alba, Ana Carolina, Foroutan, Farid, Sun, Xin, Schunemann, Holger, DeBeer, Hans, Akl, Elie A., Christensen, Robin, & Schandelmaier, Stefan. (2023). GRADE guidance 36: updates to GRADE’s approach to addressing inconsistency. Journal of Clinical Epidemiology, 158, 70–83. https://doi.org/10.1016/j.jclinepi.2023.03.003
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Hirt, J., Schönenberger, C. M., Ewald, H., Lawson, D. O., Papola, D., Rohner, R., Suter, K., Lin, S., Germini, F., Zeng, L., Shahabinezhad, A., Chowdhury, S. R., Gao, Y., Bhattacharjee, A., Lima, J. P., Marusic, A., Buljan, I., Agarwal, A., Guyatt, G. H., et al. (2023). Introducing the Library of Guidance for Health Scientists (LIGHTS): a living database for methods guidance. JAMA Netw Open, 6(2), e2253198. https://doi.org/10.1001/jamanetworkopen.2022.53198
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Klatte, Katharina, Subramaniam, Suvitha, Benkert, Pascal, Schulz, Alexandra, Ehrlich, Klaus, Rösler, Astrid, Deschodt, Mieke, Fabbro, Thomas, Pauli-Magnus, Christiane, & Briel, Matthias. (2023). Development of a risk-tailored approach and dashboard for efficient management and monitoring of investigator-initiated trials. BMC Medical Research Methodology, 23. https://doi.org/10.1186/s12874-023-01902-y
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McLennan, S., & Briel, M. (2023). A call for error management in academic clinical research. Journal of Clinical Epidemiology, 154, 208–211. https://doi.org/10.1016/j.jclinepi.2022.11.023
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Speich, Benjamin, Mann, Erika, Schönenberger, Christof M., Mellor, Katie, Griessbach, Alexandra N., Dhiman, Paula, Gandhi, Pooja, Lohner, Szimonetta, Agarwal, Arnav, Odutayo, Ayodele, Puebla, Iratxe, Clark, Alejandra, Chan, An-Wen, Schlussel, Michael M., Ravaud, Philippe, Moher, David, Briel, Matthias, Boutron, Isabelle, Schroter, Sara, & Hopewell, Sally. (2023). Reminding Peer Reviewers of Reporting Guideline Items to Improve Completeness in Published Articles: Primary Results of 2 Randomized Trials. JAMA Network Open, 6. https://doi.org/10.1001/jamanetworkopen.2023.17651
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Speich, Benjamin, Schroter, Sara, & Briel, Matthias. (2023). Guidance needed: where should randomized studies which do not assess a health outcome be registered? Journal of Clinical Epidemiology, 161, 183–184. https://doi.org/10.1016/j.jclinepi.2023.07.016
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Gloy, Viktoria, Speich, Benjamin, Griessbach, Alexandra, Taji Heravi, Ala, Schulz, Alexandra, Fabbro, Thomas, Magnus, Christiane Pauli, McLennan, Stuart, Bertram, Wendy, & Briel, Matthias. (2022). Scoping review and characteristics of publicly available checklists for assessing clinical trial feasibility [Journal-article]. BMC Medical Research Methodology, 22(1). https://doi.org/10.1186/s12874-022-01617-6
Kusejko, Katharina, Chammartin, Frédérique, Smith, Daniel, Odermatt, Marc, Schuhmacher, Julian, Koller, Michael, Günthard, Huldrych F., Briel, Matthias, Bucher, Heiner C., Speich, Benjamin, Abela, I., Aebi-Popp, K., Anagnostopoulos, A., Battegay, M., Bernasconi, E., Braun, D. L., Bucher, H. C., Calmy, A., Cavassini, M., et al. (2022). Developing and testing a Corona VaccinE tRiAL pLatform (COVERALL) to study Covid-19 vaccine response in immunocompromised patients [Journal-article]. BMC Infectious Diseases, 22(1). https://doi.org/10.1186/s12879-022-07621-x
Wang, Y., Ghadimi, M., Wang, Q., Hou, L., Zeraatkar, D., Iqbal, A., Ho, C., Yao, L., Hu, M., Ye, Z., Couban, R., Armijo-Olivo, S., Bassler, D., Briel, M., Gluud, L. L., Glasziou, P., Jackson, R., Keitz, S. A., Letelier, L. M., et al. (2022). Instruments assessing risk of bias of randomized trials frequently included items that are not addressing risk of bias issues. Journal of Clinical Epidemiology, 152, 218–225. https://doi.org/10.1016/j.jclinepi.2022.10.018
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Nørgaard B, Briel M, Chrysostomou S, Ristic Medic D, Buttigieg SC, Kiisk E, Puljak L, Bala M, Pericic TP, Lesniak W, Zając J, Lund H, & Pieper D. (2022). A systematic review of meta-research studies finds substantial methodological heterogeneity in citation analyses to monitor evidence-based research. Journal of Clinical Epidemiology, 150, 126–141. https://doi.org/10.1016/j.jclinepi.2022.06.021
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Hirt J, Ewald H, Lawson DO, Hemkens LG, Briel M, & Schandelmaier S. (2022). A systematic survey of methods guidance suggests areas for improvement regarding access, development, and transparency. Journal of Clinical Epidemiology, 149, 217–226. https://doi.org/10.1016/j.jclinepi.2022.05.005
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Schönenberger, Christof Manuel, Griessbach, Alexandra, Taji Heravi, Ala, Gryaznov, Dmitry, Gloy, Viktoria L., Lohner, Szimonetta, Klatte, Katharina, Ghosh, Nilabh, Lee, Hopin, Mansouri, Anita, Marian, Ioana R., Saccilotto, Ramon, Nury, Edris, Busse, Jason W., von Niederhäusern, Belinda, Mertz, Dominik, Blümle, Anette, Odutayo, Ayodele, Hopewell, Sally, et al. (2022). A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols [Journal-article]. Journal of Clinical Epidemiology, 149, 45–52. https://doi.org/10.1016/j.jclinepi.2022.05.014
Schönenberger CM, Griessbach A, Taji Heravi A, Gryaznov D, Gloy VL, Lohner S, Klatte K, Ghosh N, Lee H, Mansouri A, Marian IR, Saccilotto R, Nury E, Busse JW, von Niederhäusern B, Mertz D, Blümle A, Odutayo A, Hopewell S, et al. (2022). A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols. Journal of Clinical Epidemiology, 149, 45–52. https://doi.org/10.1016/j.jclinepi.2022.05.014
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Speich, Benjamin, Chammartin, Frédérique, Abela, Irene A, Amico, Patrizia, Stoeckle, Marcel P, Eichenberger, Anna L, Hasse, Barbara, Braun, Dominique L, Schuurmans, Macé M, Müller, Thomas F, Tamm, Michael, Audigé, Annette, Mueller, Nicolas J, Rauch, Andri, Günthard, Huldrych F, Koller, Michael T, Trkola, Alexandra, Briel, Matthias, Kusejko, Katharina, et al. (2022). Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial [Journal-article]. Clinical Infectious Diseases, 75(1), e585–e593. https://doi.org/10.1093/cid/ciac169
Chammartin F, Kusejko K, Pasin C, Trkola A, Briel M, Amico P, Stoekle MP, Eichenberger AL, Hasse B, Braun DL, Schuurmans MM, Müller TF, Tamm M, Mueller NJ, Rauch A, Koller MT, Günthard HF, Bucher HC, Speich B, et al. (2022). Determinants of antibody response to severe acute respiratory syndrome coronavirus 2 mRNA vaccines in people with HIV. AIDS (London, England), 36(10), 1465–1468. https://doi.org/10.1097/qad.0000000000003246
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Speich B, Odutayo A, Peckham N, Ooms A, Stokes JR, Saccilotto R, Gryaznov D, von Niederhäusern B, Copsey B, Altman DG, Briel M, & Hopewell S. (2022). A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study. Trials, 23(1), 601. https://doi.org/10.1186/s13063-022-06516-1
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Speich, Benjamin, Gryaznov, Dmitry, Busse, Jason W., Gloy, Viktoria L., Lohner, Szimonetta, Klatte, Katharina, Taji Heravi, Ala, Ghosh, Nilabh, Lee, Hopin, Mansouri, Anita, Marian, Ioana R., Saccilotto, Ramon, Nury, Edris, Kasenda, Benjamin, Ojeda–Ruiz, Elena, Schandelmaier, Stefan, Tomonaga, Yuki, Amstutz, Alain, Pauli–Magnus, Christiane, et al. (2022). Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis [Journal-article]. PLOS Medicine, 19(4), e1003980. https://doi.org/10.1371/journal.pmed.1003980
EU-Response investigators group, Diallo A, Trøseid M, Simensen VC, Boston A, Demotes J, Olsen IC, Chung F, Paiva JA, Hites M, Ader F, Arribas JR, Baratt-Due A, Melien Ø, Tacconelli E, Staub T, Greil R, Tsiodras S, Briel M, et al. (2022). Accelerating clinical trial implementation in the context of the COVID-19 pandemic: challenges, lessons learned and recommendations from DisCoVeRy and the EU-SolidAct EU response group. Clinical Microbiology and Infection : The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 28(1), 1–5. https://doi.org/10.1016/j.cmi.2021.10.011
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Kusejko, Katharina, Chammartin, Frédérique, Smith, Daniel, Odermatt, Marc, Schuhmacher, Julian, Koller, Michael, Günthard, Huldrych F., Briel, Matthias, Bucher, Heiner C., Speich, Benjamin, Abela, I., Aebi-Popp, K., Anagnostopoulos, A., Battegay, M., Bernasconi, E., Braun, D.L., Bucher, Heiner C., Calmy, A., Cavassini, M., et al. (2022). Developing and testing a Corona VaccinE tRiAL pLatform (COVERALL) to study Covid-19 vaccine response in immunocompromised patients. BMC Infectious Diseases, 22. https://doi.org/10.1186/s12879-022-07621-x
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Satalkar, Priya, McLennan, Stuart, Elger, Bernice S, von Elm, Erik, & Matthias, Briel. (2022). Investigators’ sense of failure thwarted transparency in clinical trials discontinued for poor recruitment. Journal of Clinical Epidemiology, 145, 136–143. https://doi.org/10.1016/j.jclinepi.2022.01.024
Satalkar, Priya, McLennan, Stuart, Elger, Bernice S, von Elm, Erik, & Matthias, Briel. (2022). Investigators’ sense of failure thwarted transparency in clinical trials discontinued for poor recruitment. Journal of Clinical Epidemiology, 145, 136–143. https://doi.org/10.1016/j.jclinepi.2022.01.024
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Speich, Benjamin, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé, Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas, Rauch, Andri, Günthard, Huldrych F., Koller, Michael, Trkola, Alexandra, Briel, Matthias, Kusejko, Katharina, et al. (2022). Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial. Clinical Infectious Diseases, 75, E585–E593. https://doi.org/10.1093/cid/ciac169
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Walter M.A., Nesti C, Spanjol M, Kollár A, Bütikofer L, Gloy VL, Dumont RA, Seiler CA, Christ E.R., Radojewski P, Briel M, & Kaderli RM. (2021). Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta-analysis. Cochrane Database of Systematic Reviews, 2021(11). https://doi.org/10.1002/14651858.cd013700.pub2
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Raess N., Schuetz P., Cesana-Nigro N., Winzeler B, Urwyler SA, Schaedelin S., Rodondi N, Blum M.R., Briel M., Mueller B, Christ-Crain M., & Blum CA. (2021). Influence of Prednisone on Inflammatory Biomarkers in Community-Acquired Pneumonia: Secondary Analysis of a Randomized Trial. Journal of Clinical Pharmacology, 61(11), 1406–1414. https://doi.org/10.1002/jcph.1914
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Speich B, Chammartin F, Smith D, Stoeckle MP, Amico P, Eichenberger AL, Hasse B, Schuurmans MM, Müller T, Tamm M, Dickenmann M, Abela IA, Trkola A, Hirsch HH, Manuel O, Cavassini M, Hemkens LG, Briel M, Mueller NJ, et al. (2021). A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®. Trials, 22(1), 724. https://doi.org/10.1186/s13063-021-05664-0
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Taji Heravi A, Gryaznov D, Schandelmaier S, Kasenda B, Briel M, & Adherence to SPIRIT Recommendations (ASPIRE) Study Group. (2021). Evaluation of Planned Subgroup Analysis in Protocols of Randomized Clinical Trials. JAMA Network Open, 4(10), e2131503. https://doi.org/10.1001/jamanetworkopen.2021.31503
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Heilmann E., Gregoriano C., Annane D., Reinhart K., Bouadma L., Wolff M., Chastre J., Luyt C.-E., Tubach F., Branche A.R., Briel M., Christ-Crain M., Welte T., Corti C., De Jong E., Nijsten M., De Lange D.W., Van Oers J.A.H., Beishuizen A., et al. (2021). Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients: A patient-level meta-analysis from randomized controlled trials. Age and Ageing, 50(5), 1546–1556. https://doi.org/10.1093/ageing/afab078
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Neto A.S., Tomlinson G., Sahetya S.K., Ball L., Nichol A.D., Hodgson C., Cavalcanti A.B., Briel M., de Abreu M.G., Pelosi P., Schultz M.J., & Goligher E.C. (2021). Higher PEEP for acute respiratory distress syndrome: A Bayesian meta-analysis of randomised clinical trials. Critical Care and Resuscitation, 23(2), 171–182. https://doi.org/10.51893/2021.2.oa4
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Berg, Britt-Isabelle, Werz, Simon M, Pfeifle, Martin, Schrader, Felix, Jurgens, Philipp, & Briel, Matthias. (2021). Surgery for obstructive sleep apnoea in adults. Cochrane Database of Systematic Reviews, 2021. https://doi.org/10.1002/14651858.cd012770.pub2
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Hirt, Julian, Rasadurai, Abeelan, Briel, Matthias, Düblin, Pascal, Janiaud, Perrine, & Hemkens, Lars G. (2021). Clinical trial research on COVID-19 in Germany - a systematic analysis. F1000Research, 10, 913. https://doi.org/10.12688/f1000research.55541.1
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McLennan, Stuart, Griessbach, Alexandra, Briel, Matthias, & Making Randomized Trials Affordable (MARTA) Group. (2021). Practices and Attitudes of Swiss Stakeholders Regarding Investigator-Initiated Clinical Trial Funding Acquisition and Cost Management. JAMA Network Open, 4(6), e2111847–e2111847. https://doi.org/10.1001/jamanetworkopen.2021.11847
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McLennan, Stuart, Nussbaumer-Streit, Barbara, Hemkens, Lars G., & Briel, Matthias. (2021). Barriers and Facilitating Factors for Conducting Systematic Evidence Assessments in Academic Clinical Trials. JAMA Network Open, 4, E2136577. https://doi.org/10.1001/jamanetworkopen.2021.36577
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Yip, Olivia, Huber, Evelyn, Stenz, Samuel, Zullig, Leah L., Zeller, Andreas, De Geest, Sabina M., Deschodt, Mieke, Briel, Matthias, Schwenkglenks, Matthias, Schwenkglenks, Matthias, Zúñiga, Franziska, Vounatsou, Penelope, Quinto, Carlos, Blozik, Eva, Siqeca, Flaka, & Jara, Maria José Mendieta. (2021). A contextual analysis and logic model for integrated care for frail older adults living at home: The inspire project. International Journal of Integrated Care, 21. https://doi.org/10.5334/ijic.5607
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Lawson D.O., Puljak L., Pieper D, Schandelmaier S, Collins GS, Brignardello-Petersen R, Moher D., Tugwell P, Welch VA, Samaan Z., Thombs BD, Norskov A.K., Jakobsen J.C., Allison D.B., Mayo-Wilson E, Young T., Chan AW, Briel M., Guyatt G.H., et al. (2020). Reporting of methodological studies in health research: a protocol for the development of the MethodologIcal STudy reportIng Checklist (MISTIC). BMJ Open, 10(12), e040478. https://doi.org/10.1136/bmjopen-2020-040478
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Boulesteix A.-L., Groenwold R.H.H., Abrahamowicz M., Binder H., Briel M., Hornung R., Morris T.P., Rahnenfuhrer J., & Sauerbrei W. (2020). Introduction to statistical simulations in health research. BMJ Open, 10(12). https://doi.org/10.1136/bmjopen-2020-039921
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Schünemann HJ, Ventresca M, Crowther M, Briel M, Zhou Q, Noble S, Macbeth F, Griffiths G, Garcia D, Lyman GH, Di Nisio M, Iorio A, Mbuagbaw L, Neumann I, van Es N, Brouwers M, Guyatt G, Streiff MB, Marcucci M, et al. (2020). Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis. The Lancet. Haematology, 7(10), e746–e755. https://doi.org/10.1016/s2352-3026(20)30293-3
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Walter M.A., Spanjol M., Kollar A., Butikofer L., Gloy V.L., Dumont R.A., Seiler C.A., Christ E.R., Radojewski P., Briel M., & Kaderli R.M. (2020). Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta-analysis. Cochrane Database of Systematic Reviews, 2020(8). https://doi.org/10.1002/14651858.cd013700
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Gloy V, McLennan S, Rinderknecht M, Ley B, Meier B, Driessen S, Gervasoni P, Hirschel B, Benkert P, Gilles I, von Elm E, & Briel M. (2020). Uncertainties about the need for ethics approval in Switzerland: a mixed-methods study. Swiss Medical Weekly, 150, w20318. https://doi.org/10.4414/smw.2020.20318
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Schandelmaier S, Briel M, Varadhan R, Schmid CH, Devasenapathy N, Hayward RA, Gagnier J, Borenstein M, van der Heijden GJMG, Dahabreh IJ, Sun X, Sauerbrei W, Walsh M, Ioannidis JPA, Thabane L, & Guyatt GH. (2020). Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses. CMAJ : Canadian Medical Association Journal = Journal de l’Association Medicale Canadienne, 192(32), E901–E906. https://doi.org/10.1503/cmaj.200077
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van Es N, Ventresca M, Di Nisio M, Zhou Q, Noble S, Crowther M, Briel M, Garcia D, Lyman GH, Macbeth F, Griffiths G, Iorio A, Mbuagbaw L, Neumann I, Brozek J, Guyatt G, Streiff MB, Baldeh T, Florez ID, et al. (2020). The Khorana score for prediction of venous thromboembolism in cancer patients: An individual patient data meta-analysis. Journal of Thrombosis and Haemostasis : JTH, 18(8), 1940–1951. https://doi.org/10.1111/jth.14824
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Walter SD, Thabane L, & Briel M. (2020). The fragility of trial results involves more than statistical significance alone. Journal of Clinical Epidemiology, 124, 34–41. https://doi.org/10.1016/j.jclinepi.2020.02.011
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Odutayo A, Gryaznov D, Copsey B, Monk P, Speich B, Roberts C, Vadher K, Dutton P, Briel M, Hopewell S, Altman D.G., & ASPIRE study group . (2020). Design, analysis and reporting of multi-arm trials and strategies to address multiple testing. International Journal of Epidemiology, 49(3), 968–978. https://doi.org/10.1093/ije/dyaa026
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Ventresca M, Schünemann HJ, Macbeth F, Clarke M, Thabane L, Griffiths G, Noble S, Garcia D, Marcucci M, Iorio A, Zhou Q, Crowther M, Akl EA, Lyman GH, Gloy V, DiNisio M, & Briel M. (2020). Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide. BMC Medical Research Methodology, 20(1), 113. https://doi.org/10.1186/s12874-020-00964-6
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Speich B, Schroter S, Briel M, Moher D, Puebla I, Clark A, Maia Schlüssel M, Ravaud P, Boutron I, & Hopewell S. (2020). Impact of a short version of the CONSORT checklist for peer reviewers to improve the reporting of randomised controlled trials published in biomedical journals: study protocol for a randomised controlled trial. BMJ Open, 10(3), e035114. https://doi.org/10.1136/bmjopen-2019-035114
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Walter SD, Han H, Guyatt GH, Bassler D, Bhatnagar N, Gloy V, Schandelmaier S, & Briel M. (2020). A systematic survey of randomised trials that stopped early for reasons of futility. BMC Medical Research Methodology, 20(1), 10. https://doi.org/10.1186/s12874-020-0899-1
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Treweek S, Bevan S, Bower P, Briel M, Campbell M, Christie J, Collett C, Cotton S, Devane D, El Feky A, Galvin S, Gardner H, Gillies K, Hood K, Jansen J, Littleford R, Parker A, Ramsay C, Restrup L, et al. (2020). Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed. Trials, 21(1), 33. https://doi.org/10.1186/s13063-019-3980-5
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Briel M, Speich B, von Elm E, & Gloy V. (2019). Comparison of randomized controlled trials discontinued or revised for poor recruitment and completed trials with the same research question: a matched qualitative study. Trials, 20(1), 800. https://doi.org/10.1186/s13063-019-3957-4
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Kahale LA, Guyatt GH, Agoritsas T, Briel M, Busse JW, Carrasco-Labra A, Khamis AM, Zhang Y, Hooft L, Scholten RJPM, & Akl EA. (2019). A guidance was developed to identify participants with missing outcome data in randomized controlled trials. Journal of Clinical Epidemiology, 115, 55–63. https://doi.org/10.1016/j.jclinepi.2019.07.003
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Kernen P, Steveling-Klein EH, Saccilotto RT, Raatz H, Briel M, Koller MT, Westwood M, Bucher HC, Miedinger D, & Leuppi JD. (2019). The sensitivity and specificity of the mannitol bronchial challenge test to identify asthma in different populations: a systematic review. Swiss Medical Weekly, 149, w20100. https://doi.org/10.4414/smw.2019.20100
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Walter SD, Guyatt GH, Bassler D, Briel M, Ramsay T, & Han HD. (2019). Randomised trials with provision for early stopping for benefit (or harm): The impact on the estimated treatment effect. Statistics in Medicine, 38(14), 2524–2543. https://doi.org/10.1002/sim.8142
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Blum, Steffen, Meyre, Pascal, Aeschbacher, Stefanie, Berger, Sebastian, Auberson, Chloé, Briel, Matthias, Osswald, Stefan, & Conen, David. (2019). Incidence and predictors of atrial fibrillation progression: A systematic review and meta-analysis. Heart Rhythm, 16(4), 502–510. https://doi.org/10.1016/j.hrthm.2018.10.022
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Kaderli RM, Spanjol M, Kollár A, Bütikofer L, Gloy V, Dumont RA, Seiler CA, Christ ER, Radojewski P, Briel M, & Walter MA. (2019). Therapeutic Options for Neuroendocrine Tumors: A Systematic Review and Network Meta-analysis. JAMA Oncology, 5(4), 480–489. https://doi.org/10.1001/jamaoncol.2018.6720
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Klatte, Katharina, Pauli-Magnus, Christiane, Love, Sharon, Sydes, Matthew, Benkert, Pascal, Bruni, Nicole, Ewald, Hannah, Arnaiz Jimenez, Patricia, Bonde, Marie Mi, & Briel, Matthias. (2019). Monitoring strategies for clinical intervention studies. Cochrane Database of Systematic Reviews, 2019(12). https://doi.org/10.1002/14651858.mr000051
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Meyre, Pascal, Blum, Steffen, Berger, Sebastian, Aeschbacher, Stefanie, Schoepfer, Hadrien, Briel, Matthias, Osswald, Stefan, & Conen, David. (2019). Risk of Hospital Admissions in Patients With Atrial Fibrillation: A Systematic Review and Meta-analysis. Canadian Journal of Cardiology, 35(10), 1332–1343. https://doi.org/10.1016/j.cjca.2019.05.024
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Briel M, Spoorenberg SMC, Bos WJW, & Christ-Crain M. (2018). Reply to Stern et al. (Patent No. 9). 67(9), Article 9. https://doi.org/10.1093/cid/ciy337
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Lamontagne F, Rochwerg B, Lytvyn L, Guyatt GH, Møller MH, Annane D, Kho ME, Adhikari NKJ, Machado F, Vandvik PO, Dodek P, Leboeuf R, Briel M, Hashmi M, Camsooksai J, Shankar-Hari M, Baraki MK, Fugate K, Chua S, et al. (2018). Corticosteroid therapy for sepsis: a clinical practice guideline. 362, k3284. https://doi.org/10.1136/bmj.k3284
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Kahale L.A., Diab B., Brignardello-Petersen R., Agarwal A., Mustafa R.A., Kwong J., Neumann I., Li L., Lopes L.C., Briel M., Busse J.W., Iorio A., Vandvik P.O., Alexander P.E., Guyatt G., & Akl E.A. (2018). Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey. Journal of Clinical Epidemiology, 99, 14–23. https://doi.org/10.1016/j.jclinepi.2018.02.016
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Schuetz P, Bolliger R, Merker M, Christ-Crain M, Stolz D, Tamm M, Luyt CE, Wolff M, Schroeder S, Nobre V, Reinhart K, Branche A, Damas P, Nijsten M, Deliberato RO, Verduri A, Beghé B, Cao B, Shehabi Y, et al. (2018). Procalcitonin-guided antibiotic therapy algorithms for different types of acute respiratory infections based on previous trials. Expert review of anti-infective therapy, 16(7), 555–564. https://doi.org/10.1080/14787210.2018.1496331
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von Niederhäusern B, Guyatt GH, Briel M, & Pauli-Magnus C. (2018). Academic response to improving value and reducing waste: A comprehensive framework for INcreasing QUality In patient-oriented academic clinical REsearch (INQUIRE). PLoS medicine, 15(6), e1002580. https://doi.org/10.1371/journal.pmed.1002580
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Briel M, Spoorenberg SMC, Snijders D, Torres A, Fernandez-Serrano S, Meduri GU, Gabarrús A, Blum CA, Confalonieri M, Kasenda B, Siemieniuk RAC, Boersma W, Bos WJW, Christ-Crain M, Ovidius Study Group, Capisce Study Group, & STEP Study Group. (2018). Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia: Systematic Review and Individual Patient Data Metaanalysis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 66(3), 346–354. https://doi.org/10.1093/cid/cix801
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Amstutz A, Schandelmaier S, Frei R, Surina J, Agarwal A, Alturki R, von Niederhäusern B, von Elm E, Briel M, & On Behalf Of The MAking Randomized Trials Affordable Marta Group. (2018). Funding characteristics of randomised clinical trials supported by the Swiss National Science Foundation: a retrospective cohort study. Swiss medical weekly, 148, w14587. https://doi.org/10.4414/smw.2018.14587
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Berger, Sebastian, Meyre, Pascal, Blum, Steffen, Aeschbacher, Stefanie, Ruegg, Marco, Briel, Matthias, & Conen, David. (2018). Bariatric surgery among patients with heart failure: A systematic review and meta-analysis. Open Heart, 5. https://doi.org/10.1136/openhrt-2018-000910
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Keller, Franziska, Dhaini, Suzanne, Briel, Matthias, Henrichs, Sina, Höchsmann, Christoph, Kalbermatten, Daniel, Künzli, Nino, Mollet, Annette, Puelacher, Christian, Schmidt-Trucksäss, Arno, von Niederhäusern, Belinda, & De Geest, Sabina. (2018). How to Conceptualize and Implement a PhD Program in Health Sciences—The Basel Approach [Journal-article]. Journal of Medical Education and Curricular Development, 5, 238212051877136. https://doi.org/10.1177/2382120518771364
Schuetz P, Wirz Y, Sager R, Christ-Crain M, Stolz D, Tamm M, Bouadma L, Luyt CE, Wolff M, Chastre J, Tubach F, Kristoffersen KB, Burkhardt O, Welte T, Schroeder S, Nobre V, Wei L, Bucher HC, Annane D, et al. (2018). Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis. The Lancet. Infectious diseases, 18(1), 95–107. https://doi.org/10.1016/s1473-3099(17)30592-3
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Schuetz P., Wirz Y., Sager R., Christ-Crain M., Stolz D., Tamm M., Bouadma L., Luyt C.E., Wolff M., Chastre J., Tubach F., Kristoffersen K.B., Burkhardt O., Welte T., Schroeder S., Nobre V., Wei L., Bucher HC, Bhatnagar N., et al. (2017). Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. Cochrane Database of Systematic Reviews, 2017(10). https://doi.org/10.1002/14651858.cd007498.pub3
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Akl EA, Welch V, Pottie K, Eslava-Schmalbach J, Darzi A, Sola I, Katikireddi SV, Singh J, Murad MH, Meerpohl J, Stanev R, Lang E, Matovinovic E, Shea B, Agoritsas T, Alexander PE, Snellman A, Brignardello-Petersen R, Gloss D, et al. (2017). GRADE equity guidelines 2: considering health equity in GRADE guideline development: equity extension of the guideline development checklist. Journal of clinical epidemiology, 90, 68–75. https://doi.org/10.1016/j.jclinepi.2017.01.017
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Pottie K, Welch V, Morton R, Akl EA, Eslava-Schmalbach JH, Katikireddi V, Singh J, Moja L, Lang E, Magrini N, Thabane L, Stanev R, Matovinovic E, Snellman A, Briel M, Shea B, Tugwell P, Schunemann H, Guyatt G, & Alonso-Coello P. (2017). GRADE equity guidelines 4: considering health equity in GRADE guideline development: evidence to decision process. Journal of clinical epidemiology, 90, 84–91. https://doi.org/10.1016/j.jclinepi.2017.08.001
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Welch VA, Akl EA, Guyatt G, Pottie K, Eslava-Schmalbach J, Ansari MT, de Beer H, Briel M, Dans T, Dans I, Hultcrantz M, Jull J, Katikireddi SV, Meerpohl J, Morton R, Mosdol A, Petkovic J, Schünemann HJ, Sharaf RN, et al. (2017). GRADE equity guidelines 1: considering health equity in GRADE guideline development: introduction and rationale. Journal of clinical epidemiology, 90, 59–67. https://doi.org/10.1016/j.jclinepi.2017.01.014
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Welch V.A., Akl E.A., Pottie K., Ansari M.T., Briel M., Christensen R., Dans A., Dans L., Eslava-Schmalbach J., Guyatt G., Hultcrantz M., Jull J., Katikireddi S.V., Lang E., Matovinovic E., Meerpohl J.J., Morton R.L., Mosdol A., Murad M.H., et al. (2017). GRADE equity guidelines 3: considering health equity in GRADE guideline development: rating the certainty of synthesized evidence. Journal of Clinical Epidemiology, 90, 76–83. https://doi.org/10.1016/j.jclinepi.2017.01.015
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Werz S.M., Pfeifle M., Schrader F., Jurgens P., Briel M., & Berg B.-I. (2017). Surgery for obstructive sleep apnoea in adults. Cochrane Database of Systematic Reviews, 2017(9). https://doi.org/10.1002/14651858.cd012770
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Bally M.R., Bounoure L., Gomes F., Blaser Yildirim P.Z., Gloy V.L., Briel M., & Schuetz P. (2017). Early nutritional therapy for malnourished or nutritionally at-risk adult medical inpatients. Cochrane Database of Systematic Reviews, 2017(9). https://doi.org/10.1002/14651858.cd011096.pub2
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Amstutz A, Schandelmaier S, Frei R, Surina J, Agarwal A, Olu KK, Alturki R, Von Niederhäusern B, Von Elm E, & Briel M. (2017). Discontinuation and non-publication of randomised clinical trials supported by the main public funding body in Switzerland: a retrospective cohort study. BMJ open, 7(7), e016216. https://doi.org/10.1136/bmjopen-2017-016216
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Odermatt J, Meili M, Hersberger L, Bolliger R, Christ-Crain M, Briel M, Bucher HC, Mueller B, & Schuetz P. (2017). Pro-Adrenomedullin predicts 10-year all-cause mortality in community-dwelling patients: a prospective cohort study. BMC cardiovascular disorders, 17(1), 178. https://doi.org/10.1186/s12872-017-0605-3
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Guyatt GH, Ebrahim S, Alonso-Coello P, Johnston BC, Mathioudakis AG, Briel M, Mustafa RA, Sun X, Walter SD, Heels-Ansdell D, Neumann I, Kahale LA, Iorio A, Meerpohl J, Schünemann HJ, & Akl EA. (2017). GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence. 87, 14–22. https://doi.org/10.1016/j.jclinepi.2017.05.005
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Schandelmaier, Stefan, Schandelmaier S., Briel, Matthias, Saccilotto, Ramon, Arpagaus, Armon, Arpagaus A, Hemkens L.G., & Nordmann, Alain J. (2017). Niacin for primary and secondary prevention of cardiovascular events. Cochrane Database of Systematic Reviews, 2017(6), CD009744. https://doi.org/10.1002/14651858.cd009744.pub2
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Walter SD, Han H, Briel M, & Guyatt GH. (2017). Quantifying the bias in the estimated treatment effect in randomized trials having interim analyses and a rule for early stopping for futility. Statistics in medicine, 36(9), 1506–1518. https://doi.org/10.1002/sim.7242
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Brunner, Philippe, Jörg, Ann-Catherine, Glatz, Katharina, Bubendorf, Lukas, Radojewski, Piotr, Umlauft, Maria, Marincek, Nicolas, Spanjol, Petar-Marko, Krause, Thomas, Dumont, Rebecca A, Maecke, Helmut R, Müller-Brand, Jan, Briel, Matthias, Schmitt, Anja, Perren, Aurel, & Walter, Martin A. (2017). The prognostic and predictive value of sstr(2)-immunohistochemistry and sstr(2)-targeted imaging in neuroendocrine tumors. European journal of nuclear medicine and molecular imaging, 44(3), 468–475. https://doi.org/10.1007/s00259-016-3486-2
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Murad MH, Guyatt GH, Domecq JP, Vernooij RWM, Erwin PJ, Meerpohl JJ, Prutsky GJ, Akl EA, Mueller K, Bassler D, Schandelmaier S, Walter SD, Busse JW, Kasenda B, Pagano G, Pardo-Hernandez H, Montori VM, Wang Z, & Briel M. (2017). Randomized trials addressing a similar question are commonly published after a trial stopped early for benefit. Journal of clinical epidemiology, 82, 12–19. https://doi.org/10.1016/j.jclinepi.2016.10.006
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Agarwal A, Johnston BC, Vernooij RW, Carrasco-Labra A, Brignardello-Petersen R, Neumann I, Akl EA, Sun X, Briel M, Busse JW, Ebrahim S, Granados CE, Iorio A, Irfan A, Martínez García L, Mustafa RA, Ramirez-Morera A, Selva A, Solà I, et al. (2017). Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review abstracts. Journal of clinical epidemiology, 81, 3–12. https://doi.org/10.1016/j.jclinepi.2016.08.004
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Alturki R, Schandelmaier S, Olu KK, von Niederhäusern B, Agarwal A, Frei R, Bhatnagar N, Hooft L, von Elm E, & Briel M. (2017). Premature trial discontinuation often not accurately reflected in registries: comparison of registry records with publications. Journal of clinical epidemiology, 81, 56–63. https://doi.org/10.1016/j.jclinepi.2016.08.011
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Ewald, Hannah, Santini-Oliveira, Marilia, Bühler, Julian-Emanuel, Vuichard, Danielle, Schandelmaier, Stefan, Stöckle, Marcel, Briel, Matthias, Bucher, Heiner C., & Hemkens, Lars G. (2017). Comparative effectiveness of tenofovir in HIV-infected treatment-experienced patients: systematic review and meta-analysis. HIV clinical trials, 18(1), 17–27. https://doi.org/10.1080/15284336.2016.1261073
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Odermatt J., Friedli N., Kutz A., Briel M., Bucher H.C., Christ-Crain M., Burkhardt O., Welte T., Mueller B., & Schuetz P. (2017). Effects of procalcitonin testing on antibiotic use and clinical outcomes in patients with upper respiratory tract infections. An individual patient data meta-analysis. Clinical Chemistry and Laboratory Medicine, 56, 170–177. https://doi.org/10.1515/cclm-2017-0252
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Schmucker CM, Blümle A, Schell LK, Schwarzer G, Oeller P, Cabrera L, von Elm E, Briel M, Meerpohl JJ, & OPEN consortium. (2017). Systematic review finds that study data not published in full text articles have unclear impact on meta-analyses results in medical research. PloS one, 12(4), e0176210. https://doi.org/10.1371/journal.pone.0176210
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von Niederhäusern B, Schandelmaier S, Mi Bonde M, Brunner N, Hemkens LG, Rutquist M, Bhatnagar N, Guyatt GH, Pauli-Magnus C, & Briel M. (2017). Towards the development of a comprehensive framework: Qualitative systematic survey of definitions of clinical research quality. PloS one, 12(7), e0180635. https://doi.org/10.1371/journal.pone.0180635
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Briel M, Olu KK, von Elm E, Kasenda B, Alturki R, Agarwal A, Bhatnagar N, & Schandelmaier S. (2016). A systematic review of discontinued trials suggested that most reasons for recruitment failure were preventable. Journal of Clinical Epidemiology, 80, 8–15. https://doi.org/10.1016/j.jclinepi.2016.07.016
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Mueller KF, Meerpohl JJ, Briel M, Antes G, von Elm E, Lang B, Motschall E, Schwarzer G, & Bassler D. (2016). Methods for detecting, quantifying, and adjusting for dissemination bias in meta-analysis are described. Journal of clinical epidemiology, 80, 25–33. https://doi.org/10.1016/j.jclinepi.2016.04.015
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Jakob, Tobias, Nordmann, Alain J, Schandelmaier, Stefan, Schandelmaier S, Ferreira-González, Ignacio, & Briel M. (2016). Fibrates for primary prevention of cardiovascular disease events. The Cochrane Database of Systematic Reviews, 11(11), CD009753. https://doi.org/10.1002/14651858.cd009753.pub2
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Hemkens LG, Benchimol EI, Langan SM, Briel M, Kasenda B, Januel JM, Herrett E, & von Elm E. (2016). The reporting of studies using routinely collected health data was often insufficient. Journal of Clinical Epidemiology, 79, 104–111. https://doi.org/10.1016/j.jclinepi.2016.06.005
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