Prof. Dr. Dr. Matthias Briel

Hirt, Julian, Ewald, Hannah, Briel, Matthias, & Schandelmaier, Stefan. (2024). Searching a methods topic: practical challenges and implications for search design. Journal of Clinical Epidemiology, 166. https://doi.org/10.1016/j.jclinepi.2023.10.017

Puljak, Livia, Bala, Małgorzata M., Zając, Joanna, Meštrović, Tomislav, Buttigieg, Sandra, Yanakoulia, Mary, Briel, Matthias, Lunny, Carole, Lesniak, Wiktoria, Poklepović Peričić, Tina, Alonso-Coello, Pablo, Clarke, Mike, Djulbegovic, Benjamin, Gartlehner, Gerald, Giannakou, Konstantinos, Glenny, Anne-Marie, Glenton, Claire, Guyatt, Gordon, Hemkens, Lars G., et al. (2024). Methods proposed for monitoring the implementation of evidence-based research: a cross-sectional study [Journal-article]. Journal of Clinical Epidemiology, 168, 111247. https://doi.org/10.1016/j.jclinepi.2024.111247

Wang, Y., Parpia, S., Couban, R., Wang, Q., Armijo-Olivo, S., Bassler, D., Briel, M., Brignardello-Petersen, R., Gluud, L. L., Keitz, S. A., Letelier, L. M., Ravaud, P., Schulz, K. F., Siemieniuk, R. A. C., Zeraatkar, D., & Guyatt, G. H. (2024). Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors. Journal of Clinical Epidemiology, 165. https://doi.org/10.1016/j.jclinepi.2023.11.001

Klatte, K., Sluka, C., Gloy, V., Heravi, A. T., Schönenberger, C., Jones, N., Brunnschweiler, E., Pauli-Magnus, C., & Briel, M. (2023). Towards full clinical trial registration and results publication: longitudinal meta-research study in Northwestern and Central Switzerland. BMC Medical Research Methodology, 23(1). https://doi.org/10.1186/s12874-023-01840-9

Troseid M., Arribas J.R., Assoumou L., Holten A.R., Poissy J., Terzic V., Mazzaferri F., Bano J.R., Eustace J., Hites M., Joannidis M., Paiva J.-A., Reuter J., Puntmann I., Patrick-Brown T.D.J.H., Westerheim E., Nezvalova-Henriksen K., Beniguel L., Dahl T.B., et al. (2023). Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial. Critical Care, 27(1). https://doi.org/10.1186/s13054-022-04205-8

Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A, Amico, Patrizia, Stoeckle, Marcel P, Eichenberger, Anna L, Hasse, Barbara, Braun, Dominique L, Schuurmans, Macé M, Müller, Thomas F, Tamm, Michael, Audigé, Annette, Mueller, Nicolas J, Rauch, Andri, Günthard, Huldrych F, Koller, Michael T, Trkola, Alexandra, Epp, Selina, Amstutz, Alain, et al. (2023). Antibody Response After the Third SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients and People Living With HIV (COVERALL-2) [Journal-article]. Open Forum Infectious Diseases, 10(11). https://doi.org/10.1093/ofid/ofad536

Yao, M., Wang, Y., Busse, J. W., Briel, M., Mei, F., Li, G., Zou, K., Li, L., & Sun, X. (2023). Evaluating the impact of including non-randomised studies of interventions in meta-analysis of randomised controlled trials: A protocol for a meta-epidemiological study. BMJ Open, 13(7). https://doi.org/10.1136/bmjopen-2023-073232

Amstutz, Alain, Speich, Benjamin, Mentré, France, Rueegg, Corina Silvia, Belhadi, Drifa, Assoumou, Lambert, Burdet, Charles, Murthy, Srinivas, Dodd, Lori Elizabeth, Wang, Yeming, Tikkinen, Kari A O, Ader, Florence, Hites, Maya, Bouscambert, Maude, Trabaud, Mary Anne, Fralick, Mike, Lee, Todd C, Pinto, Ruxandra, Barratt-Due, Andreas, et al. (2023). Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials. The Lancet Respiratory Medicine, 11(5), 453–464. https://doi.org/10.1016/s2213-2600(22)00528-8

Blum, Claudine A., Roethlisberger, Eva A., Cesana-Nigro, Nicole, Winzeler, Bettina, Rodondi, Nicolas, Blum, Manuel R., Briel, Matthias, Mueller, Beat, Christ-Crain, Mirjam, & Schuetz, Philipp. (2023). Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial. BMC Pulmonary Medicine, 23. https://doi.org/10.1186/s12890-023-02794-w

Ebrahimi, Fahim, Hirt, Julian, Schönenberger, Christof, Ewald, Hannah, Briel, Matthias, Janiaud, Perrine, & Hemkens, Lars G. (2023). Colchicine for the secondary prevention of cardiovascular events. Cochrane Database of Systematic Reviews, 2023(8). https://doi.org/10.1002/14651858.cd014808

Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé M., Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas J., Rauch, Andri, Günthard, Huldrych F., Koller, Michael T., Trkola, Alexandra, Epp, Selina, Amstutz, Alain, et al. (2023). Antibody Response After Third Vaccination With mRNA-1273 or BNT162b2: Extension of a Randomized Controlled SARS-CoV-2 Noninferiority Vaccine Trial in Patients With Different Levels of Immunosuppression (COVERALL-2). Open Forum Infectious Diseases, 10. https://doi.org/10.1093/ofid/ofad150

Griessbach, Alexandra, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé M., Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas J., Rauch, Andri, Günthard, Huldrych F., Koller, Michael T., Trkola, Alexandra, Epp, Selina, Amstutz, Alain, et al. (2023). Antibody Response After the Third SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients and People Living With HIV (COVERALL-2). Open Forum Infectious Diseases, 10. https://doi.org/10.1093/ofid/ofad536

Guyatt, Gordon, Zhao, Yunli, Mayer, Martin, Briel, Matthias, Mustafa, Reem, Izcovich, Ariel, Hultcrantz, Monica, Iorio, Alfonso, Alba, Ana Carolina, Foroutan, Farid, Sun, Xin, Schunemann, Holger, DeBeer, Hans, Akl, Elie A., Christensen, Robin, & Schandelmaier, Stefan. (2023). GRADE guidance 36: updates to GRADE’s approach to addressing inconsistency. Journal of Clinical Epidemiology, 158, 70–83. https://doi.org/10.1016/j.jclinepi.2023.03.003

Hirt, J., Schönenberger, C. M., Ewald, H., Lawson, D. O., Papola, D., Rohner, R., Suter, K., Lin, S., Germini, F., Zeng, L., Shahabinezhad, A., Chowdhury, S. R., Gao, Y., Bhattacharjee, A., Lima, J. P., Marusic, A., Buljan, I., Agarwal, A., Guyatt, G. H., et al. (2023). Introducing the Library of Guidance for Health Scientists (LIGHTS): a living database for methods guidance. JAMA Netw Open, 6(2), e2253198. https://doi.org/10.1001/jamanetworkopen.2022.53198

Klatte, Katharina, Subramaniam, Suvitha, Benkert, Pascal, Schulz, Alexandra, Ehrlich, Klaus, Rösler, Astrid, Deschodt, Mieke, Fabbro, Thomas, Pauli-Magnus, Christiane, & Briel, Matthias. (2023). Development of a risk-tailored approach and dashboard for efficient management and monitoring of investigator-initiated trials. BMC Medical Research Methodology, 23. https://doi.org/10.1186/s12874-023-01902-y

McLennan, S., & Briel, M. (2023). A call for error management in academic clinical research. Journal of Clinical Epidemiology, 154, 208–211. https://doi.org/10.1016/j.jclinepi.2022.11.023

Speich, Benjamin, Mann, Erika, Schönenberger, Christof M., Mellor, Katie, Griessbach, Alexandra N., Dhiman, Paula, Gandhi, Pooja, Lohner, Szimonetta, Agarwal, Arnav, Odutayo, Ayodele, Puebla, Iratxe, Clark, Alejandra, Chan, An-Wen, Schlussel, Michael M., Ravaud, Philippe, Moher, David, Briel, Matthias, Boutron, Isabelle, Schroter, Sara, & Hopewell, Sally. (2023). Reminding Peer Reviewers of Reporting Guideline Items to Improve Completeness in Published Articles: Primary Results of 2 Randomized Trials. JAMA Network Open, 6. https://doi.org/10.1001/jamanetworkopen.2023.17651

Speich, Benjamin, Schroter, Sara, & Briel, Matthias. (2023). Guidance needed: where should randomized studies which do not assess a health outcome be registered? Journal of Clinical Epidemiology, 161, 183–184. https://doi.org/10.1016/j.jclinepi.2023.07.016

Hirt, Julian, Ewald, Hannah, Briel, Matthias, & Schandelmaier, Stefan. (2022). Library of Guidance for Health Scientists (LIGHTS): Eine neue Datenbank für methodische Leitlinien in der klinischen Forschung. GMS Medizin - Bibliothek - Information, 22(2). https://doi.org/10.3205/mbi000546

Gloy, Viktoria, Speich, Benjamin, Griessbach, Alexandra, Taji Heravi, Ala, Schulz, Alexandra, Fabbro, Thomas, Magnus, Christiane Pauli, McLennan, Stuart, Bertram, Wendy, & Briel, Matthias. (2022). Scoping review and characteristics of publicly available checklists for assessing clinical trial feasibility [Journal-article]. BMC Medical Research Methodology, 22(1). https://doi.org/10.1186/s12874-022-01617-6

Kusejko, Katharina, Chammartin, Frédérique, Smith, Daniel, Odermatt, Marc, Schuhmacher, Julian, Koller, Michael, Günthard, Huldrych F., Briel, Matthias, Bucher, Heiner C., Speich, Benjamin, Abela, I., Aebi-Popp, K., Anagnostopoulos, A., Battegay, M., Bernasconi, E., Braun, D. L., Bucher, H. C., Calmy, A., Cavassini, M., et al. (2022). Developing and testing a Corona VaccinE tRiAL pLatform (COVERALL) to study Covid-19 vaccine response in immunocompromised patients [Journal-article]. BMC Infectious Diseases, 22(1). https://doi.org/10.1186/s12879-022-07621-x

Wang, Y., Ghadimi, M., Wang, Q., Hou, L., Zeraatkar, D., Iqbal, A., Ho, C., Yao, L., Hu, M., Ye, Z., Couban, R., Armijo-Olivo, S., Bassler, D., Briel, M., Gluud, L. L., Glasziou, P., Jackson, R., Keitz, S. A., Letelier, L. M., et al. (2022). Instruments assessing risk of bias of randomized trials frequently included items that are not addressing risk of bias issues. Journal of Clinical Epidemiology, 152, 218–225. https://doi.org/10.1016/j.jclinepi.2022.10.018

Klatte, K., Subramaniam, S., Benkert, P., Schulz, A., Ehrlich, K., Rösler, A., Deschodt, M., Fabbro, T., Pauli-Magnus, C., & Briel, M. (2022, November 18). Development of a Risk-tailored Approach and Dashboard for Efficient Management and Monitoring of Investigator-Initiated Trials [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.3.rs-2051504/v1

Nørgaard B, Briel M, Chrysostomou S, Ristic Medic D, Buttigieg SC, Kiisk E, Puljak L, Bala M, Pericic TP, Lesniak W, Zając J, Lund H, & Pieper D. (2022). A systematic review of meta-research studies finds substantial methodological heterogeneity in citation analyses to monitor evidence-based research. Journal of Clinical Epidemiology, 150, 126–141. https://doi.org/10.1016/j.jclinepi.2022.06.021

Hirt J, Ewald H, Lawson DO, Hemkens LG, Briel M, & Schandelmaier S. (2022). A systematic survey of methods guidance suggests areas for improvement regarding access, development, and transparency. Journal of Clinical Epidemiology, 149, 217–226. https://doi.org/10.1016/j.jclinepi.2022.05.005

Schönenberger, Christof Manuel, Griessbach, Alexandra, Taji Heravi, Ala, Gryaznov, Dmitry, Gloy, Viktoria L., Lohner, Szimonetta, Klatte, Katharina, Ghosh, Nilabh, Lee, Hopin, Mansouri, Anita, Marian, Ioana R., Saccilotto, Ramon, Nury, Edris, Busse, Jason W., von Niederhäusern, Belinda, Mertz, Dominik, Blümle, Anette, Odutayo, Ayodele, Hopewell, Sally, et al. (2022). A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols [Journal-article]. Journal of Clinical Epidemiology, 149, 45–52. https://doi.org/10.1016/j.jclinepi.2022.05.014

Schönenberger CM, Griessbach A, Taji Heravi A, Gryaznov D, Gloy VL, Lohner S, Klatte K, Ghosh N, Lee H, Mansouri A, Marian IR, Saccilotto R, Nury E, Busse JW, von Niederhäusern B, Mertz D, Blümle A, Odutayo A, Hopewell S, et al. (2022). A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols. Journal of Clinical Epidemiology, 149, 45–52. https://doi.org/10.1016/j.jclinepi.2022.05.014

Speich, Benjamin, Chammartin, Frédérique, Abela, Irene A, Amico, Patrizia, Stoeckle, Marcel P, Eichenberger, Anna L, Hasse, Barbara, Braun, Dominique L, Schuurmans, Macé M, Müller, Thomas F, Tamm, Michael, Audigé, Annette, Mueller, Nicolas J, Rauch, Andri, Günthard, Huldrych F, Koller, Michael T, Trkola, Alexandra, Briel, Matthias, Kusejko, Katharina, et al. (2022). Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial [Journal-article]. Clinical Infectious Diseases, 75(1), e585–e593. https://doi.org/10.1093/cid/ciac169

Chammartin F, Kusejko K, Pasin C, Trkola A, Briel M, Amico P, Stoekle MP, Eichenberger AL, Hasse B, Braun DL, Schuurmans MM, Müller TF, Tamm M, Mueller NJ, Rauch A, Koller MT, Günthard HF, Bucher HC, Speich B, et al. (2022). Determinants of antibody response to severe acute respiratory syndrome coronavirus 2 mRNA vaccines in people with HIV. AIDS (London, England), 36(10), 1465–1468. https://doi.org/10.1097/qad.0000000000003246

Speich B, Odutayo A, Peckham N, Ooms A, Stokes JR, Saccilotto R, Gryaznov D, von Niederhäusern B, Copsey B, Altman DG, Briel M, & Hopewell S. (2022). A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study. Trials, 23(1), 601. https://doi.org/10.1186/s13063-022-06516-1

Speich, Benjamin, Gryaznov, Dmitry, Busse, Jason W., Gloy, Viktoria L., Lohner, Szimonetta, Klatte, Katharina, Taji Heravi, Ala, Ghosh, Nilabh, Lee, Hopin, Mansouri, Anita, Marian, Ioana R., Saccilotto, Ramon, Nury, Edris, Kasenda, Benjamin, Ojeda–Ruiz, Elena, Schandelmaier, Stefan, Tomonaga, Yuki, Amstutz, Alain, Pauli–Magnus, Christiane, et al. (2022). Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis [Journal-article]. PLOS Medicine, 19(4), e1003980. https://doi.org/10.1371/journal.pmed.1003980

Amacher, Simon A., Blatter, René, Briel, Matthias, Appenzeller-Herzog, Christian, Bohren, Chantal, Becker, Christoph, Beck, Katharina, Gross, Sebastian, Tisljar, Kai, Sutter, Raoul, Marsch, Stephan, & Hunziker, Sabina. (2022). Predicting neurological outcome in adult patients with cardiac arrest: systematic review and meta-analysis of prediction model performance. Critical Care, 26(1), 382. https://doi.org/10.1186/s13054-022-04263-y

Trøseid, M., Arribas, J., Assoumou, L., Holten, A. R., Poissy, J., Terzić, V., Mazzaferri, F., Rodríguez-Baño, J., Eustace, J., Hites, M., Joannidis, M., Paiva, J.-A., Reuter, J., Püntmann, I., Patrick-Brown, T., Westerheim, E., Nezvalova-Henriksen, K., Beniguel, L., Dahl, T. B., et al. (2022). Efficacy and Safety of Baricitinib for the Treatment of Hospitalized Adults with Severe or Critical COVID-19 (Bari-SolidAct): A Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Trial [Journal-article]. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.4172086

Briel, Matthias, Elger, Bernice S., McLennan, Stuart, Schandelmaier, Stefan, von Elm, Erik, & Satalkar, Priya. (2022). Exploring reasons for recruitment failure in clinical trials: a qualitative study with clinical trial stakeholders in Switzerland, Germany, and Canada. Trials, 22(1), 844. https://doi.org/10.1186/s13063-021-05818-0

EU-Response investigators group, Diallo A, Trøseid M, Simensen VC, Boston A, Demotes J, Olsen IC, Chung F, Paiva JA, Hites M, Ader F, Arribas JR, Baratt-Due A, Melien Ø, Tacconelli E, Staub T, Greil R, Tsiodras S, Briel M, et al. (2022). Accelerating clinical trial implementation in the context of the COVID-19 pandemic: challenges, lessons learned and recommendations from DisCoVeRy and the EU-SolidAct EU response group. Clinical Microbiology and Infection : The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 28(1), 1–5. https://doi.org/10.1016/j.cmi.2021.10.011

Gloy, V., Speich, B., Griessbach, A., Taji Heravi, A., Schulz, A., Fabbro, T., Magnus, C. P., McLennan, S., Bertram, W., & Briel, M. (2022). Scoping review and characteristics of publicly available checklists for assessing clinical trial feasibility. BMC Med Res Methodol, 22(1), 142. https://doi.org/10.1186/s12874-022-01617-6

Gryaznov, D., von Niederhäusern, B., Speich, B., Kasenda, B., Ojeda-Ruiz, E., Blümle, A., Schandelmaier, S., Mertz, D., Odutayo, A., Tomonaga, Y., Amstutz, A., Pauli-Magnus, C., Gloy, V., Lohner, S., Bischoff, K., Wollmann, K., Rehner, L., Meerpohl, J. J., Nordmann, A., et al. (2022). Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE). BMJ Open, 12(5), e053417. https://doi.org/10.1136/bmjopen-2021-053417

Kusejko, Katharina, Chammartin, Frédérique, Smith, Daniel, Odermatt, Marc, Schuhmacher, Julian, Koller, Michael, Günthard, Huldrych F., Briel, Matthias, Bucher, Heiner C., Speich, Benjamin, Abela, I., Aebi-Popp, K., Anagnostopoulos, A., Battegay, M., Bernasconi, E., Braun, D.L., Bucher, Heiner C., Calmy, A., Cavassini, M., et al. (2022). Developing and testing a Corona VaccinE tRiAL pLatform (COVERALL) to study Covid-19 vaccine response in immunocompromised patients. BMC Infectious Diseases, 22. https://doi.org/10.1186/s12879-022-07621-x

Amstutz, A., Speich, B., Mentré, F., Rueegg, C. S., Belhadi, D., Assoumou, L., Burdet, C., Murthy, S., Dodd, L. E., Wang, Y., Tikkinen, K., Ader, F., Hites, M., Bouscambert-Duchamp, M., Trabaud, M.-A., Fralick, M., Lee, T. C., Pinto, R., Barratt-Due, A., et al. (2022). Effects of Remdesivir in Hospitalized Patients with COVID-19: Systematic Review and Individual Patient Data Meta-Analysis of Randomized Clinical Trials [Journal-article]. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.4244759

Satalkar, Priya, McLennan, Stuart, Elger, Bernice S, von Elm, Erik, & Matthias, Briel. (2022). Investigators’ sense of failure thwarted transparency in clinical trials discontinued for poor recruitment. Journal of Clinical Epidemiology, 145, 136–143. https://doi.org/10.1016/j.jclinepi.2022.01.024

Satalkar, Priya, McLennan, Stuart, Elger, Bernice S, von Elm, Erik, & Matthias, Briel. (2022). Investigators’ sense of failure thwarted transparency in clinical trials discontinued for poor recruitment. Journal of Clinical Epidemiology, 145, 136–143. https://doi.org/10.1016/j.jclinepi.2022.01.024

Siqeca, Flaka, Yip, Olivia, Mendieta, Maria José, Schwenkglenks, Matthias, Zeller, Andreas, De Geest, Sabina, Zúñiga, Franziska, Stenz, Samuel, Briel, Matthias, Quinto, Carlos, Blozik, Eva, Deschodt, Mieke, Obas, Katrina, & Dhaini, Suzanne. (2022). Factors associated with health-related quality of life among home-dwelling older adults aged 75 or older in Switzerland: a cross-sectional study. Health and Quality of Life Outcomes, 20(1), 166. https://doi.org/10.1186/s12955-022-02080-z

Speich, Benjamin, Chammartin, Frédérique, Abela, Irene A., Amico, Patrizia, Stoeckle, Marcel P., Eichenberger, Anna L., Hasse, Barbara, Braun, Dominique L., Schuurmans, Macé, Müller, Thomas F., Tamm, Michael, Audigé, Annette, Mueller, Nicolas, Rauch, Andri, Günthard, Huldrych F., Koller, Michael, Trkola, Alexandra, Briel, Matthias, Kusejko, Katharina, et al. (2022). Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial. Clinical Infectious Diseases, 75, E585–E593. https://doi.org/10.1093/cid/ciac169

Speich, B., Gryaznov, D., Busse, J. W., Gloy, V. L., Lohner, S., Klatte, K., Taji Heravi, A., Ghosh, N., Lee, H., Mansouri, A., Marian, I. R., Saccilotto, R., Nury, E., Kasenda, B., Ojeda-Ruiz, E., Schandelmaier, S., Tomonaga, Y., Amstutz, A., Pauli-Magnus, C., et al. (2022). Nonregistration, discontinuation, and nonpublication of randomized trials: a repeated metaresearch analysis. PLoS Med, 19(4), e1003980. https://doi.org/10.1371/journal.pmed.1003980

Taji Heravi, A., Henn, A., Deuster, S., McLennan, S., Gloy, V., Mitter, V. R., Briel, M., & Making Randomized Trials Affordable Group,. (2022). Investigational medicinal products, related costs and hospital pharmacy services for investigator-initiated trials: a mixed-methods study. PLoS One, 17(3), e0264427. https://doi.org/10.1371/journal.pone.0264427

Yip, Olivia, Mendieta, Maria Jose, Zullig, Leah L., Zeller, Andreas, De Geest, Sabina, Deschodt, Mieke, Siqeca, Flaka, Zúñiga, Franziska, Briel, Matthias, Schwenkglenks, Matthias, Quinto, Carlos, & Dhaini, Suzanne. (2022). Protocol for a mixed methods feasibility and implementation study of a community-based integrated care model for home-dwelling older adults: The INSPIRE project. PLoS ONE, 17(12), e0278767. https://doi.org/10.1371/journal.pone.0278767

Walter M.A., Nesti C, Spanjol M, Kollár A, Bütikofer L, Gloy VL, Dumont RA, Seiler CA, Christ E.R., Radojewski P, Briel M, & Kaderli RM. (2021). Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta-analysis. Cochrane Database of Systematic Reviews, 2021(11). https://doi.org/10.1002/14651858.cd013700.pub2

Raess N., Schuetz P., Cesana-Nigro N., Winzeler B, Urwyler SA, Schaedelin S., Rodondi N, Blum M.R., Briel M., Mueller B, Christ-Crain M., & Blum CA. (2021). Influence of Prednisone on Inflammatory Biomarkers in Community-Acquired Pneumonia: Secondary Analysis of a Randomized Trial. Journal of Clinical Pharmacology, 61(11), 1406–1414. https://doi.org/10.1002/jcph.1914

Speich B, Chammartin F, Smith D, Stoeckle MP, Amico P, Eichenberger AL, Hasse B, Schuurmans MM, Müller T, Tamm M, Dickenmann M, Abela IA, Trkola A, Hirsch HH, Manuel O, Cavassini M, Hemkens LG, Briel M, Mueller NJ, et al. (2021). A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®. Trials, 22(1), 724. https://doi.org/10.1186/s13063-021-05664-0

Taji Heravi A, Gryaznov D, Schandelmaier S, Kasenda B, Briel M, & Adherence to SPIRIT Recommendations (ASPIRE) Study Group. (2021). Evaluation of Planned Subgroup Analysis in Protocols of Randomized Clinical Trials. JAMA Network Open, 4(10), e2131503. https://doi.org/10.1001/jamanetworkopen.2021.31503

Heilmann E., Gregoriano C., Annane D., Reinhart K., Bouadma L., Wolff M., Chastre J., Luyt C.-E., Tubach F., Branche A.R., Briel M., Christ-Crain M., Welte T., Corti C., De Jong E., Nijsten M., De Lange D.W., Van Oers J.A.H., Beishuizen A., et al. (2021). Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients: A patient-level meta-analysis from randomized controlled trials. Age and Ageing, 50(5), 1546–1556. https://doi.org/10.1093/ageing/afab078

Neto A.S., Tomlinson G., Sahetya S.K., Ball L., Nichol A.D., Hodgson C., Cavalcanti A.B., Briel M., de Abreu M.G., Pelosi P., Schultz M.J., & Goligher E.C. (2021). Higher PEEP for acute respiratory distress syndrome: A Bayesian meta-analysis of randomised clinical trials. Critical Care and Resuscitation, 23(2), 171–182. https://doi.org/10.51893/2021.2.oa4

Berg, Britt-Isabelle, Werz, Simon M, Pfeifle, Martin, Schrader, Felix, Jurgens, Philipp, & Briel, Matthias. (2021). Surgery for obstructive sleep apnoea in adults. Cochrane Database of Systematic Reviews, 2021. https://doi.org/10.1002/14651858.cd012770.pub2

Herbrand, Amanda Katherina, Schmitt, Andreas M., Briel, Matthias, Ewald, Hannah, Goldkuhle, Marius, Diem, Stefan, Hoogkamer, Anouk, Joerger, Markus, Moffa, Giusi, Novak, Urban, Hemkens, Lars G., & Kasenda, Benjamin. (2021). Association of Supporting Trial Evidence and Reimbursement for Off-Label Use of Cancer Drugs. Jama Network Open, 4(3), e210380. https://doi.org/10.1001/jamanetworkopen.2021.0380

Hirt, Julian, Rasadurai, Abeelan, Briel, Matthias, Düblin, Pascal, Janiaud, Perrine, & Hemkens, Lars G. (2021). Clinical trial research on COVID-19 in Germany - a systematic analysis. F1000Research, 10, 913. https://doi.org/10.12688/f1000research.55541.1

Klatte, Katharina, Pauli-Magnus, Christiane, Love, Sharon B., Sydes, Matthew R., Benkert, Pascal, Bruni, Nicole, Ewald, Hannah, Arnaiz Jimenez, Patricia, Bonde, Marie Mi, & Briel, Matthias. (2021). Monitoring strategies for clinical intervention studies. Cochrane Database of Systematic Reviews, 12(12), MR000051. https://doi.org/10.1002/14651858.mr000051.pub2

Lohner, Szimonetta, Gryaznov, Dmitry, von Niederhäusern, Belinda, Speich, Benjamin, Kasenda, Benjamin, Ojeda-Ruiz, Elena, Schandelmaier, Stefan, Mertz, Dominik, Odutayo, Ayodele, Tomonaga, Yuki, Amstutz, Alain, Pauli-Magnus, Christiane, Gloy, Viktoria, Bischoff, Karin, Wollmann, Katharina, Rehner, Laura, Meerpohl, Joerg J., Nordmann, Alain, Klatte, Katharina, et al. (2021). Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: A repeated cross-sectional study. Journal of Clinical Epidemiology, 139, 340–349. https://doi.org/10.1016/j.jclinepi.2021.05.011

McLennan, Stuart, Griessbach, Alexandra, Briel, Matthias, & Making Randomized Trials Affordable (MARTA) Group. (2021). Practices and Attitudes of Swiss Stakeholders Regarding Investigator-Initiated Clinical Trial Funding Acquisition and Cost Management. JAMA Network Open, 4(6), e2111847–e2111847. https://doi.org/10.1001/jamanetworkopen.2021.11847

McLennan, Stuart, Nussbaumer-Streit, Barbara, Hemkens, Lars G., & Briel, Matthias. (2021). Barriers and Facilitating Factors for Conducting Systematic Evidence Assessments in Academic Clinical Trials. JAMA Network Open, 4, E2136577. https://doi.org/10.1001/jamanetworkopen.2021.36577

Siqeca, Flaka, Obas, Katrina, Yip, Olivia, Stenz, Samuel, Vounatsou, Penelope, Briel, Matthias, Schwenkglenks, Matthias, Quinto, Carlos, Blozik, Eva, Zeller, Andreas, Zullig, Leah L., De Geest, Sabina, & Deschodt, Mieke. (2021). The INSPIRE Population Survey: development, dissemination and respondent characteristics. BMC Medical Research Methodology, 21(1), 131. https://doi.org/10.1186/s12874-021-01329-3

Speich, B., Gloy, V. L., Klatte, K., Gryaznov, D., Taji Heravi, A., Ghosh, N., Marian, I. R., Lee, H., Mansouri, A., Lohner, S., Saccilotto, R., Nury, E., Chan, A. W., Blümle, A., Odutayo, A., Hopewell, S., & Briel, M. (2021). Reliability of trial information across registries for trials with multiple registrations: a systematic review. JAMA Netw Open, 4(11), e2128898. https://doi.org/10.1001/jamanetworkopen.2021.28898

Speich, B., Logullo, P., Deuster, S., Marian, I. R., Moschandreas, J., Taji Heravi, A., Gloy, V., Briel, M., Hopewell, S., & Making Randomized Trials Affordable Group. (2021). A meta-research study revealed several challenges in obtaining placebos for investigator-initiated drug trials. J Clin Epidemiol, 131, 70–78. https://doi.org/10.1016/j.jclinepi.2020.11.007

Yip, Olivia, Huber, Evelyn, Stenz, Samuel, Zullig, Leah L., Zeller, Andreas, De Geest, Sabina M., Deschodt, Mieke, Briel, Matthias, Schwenkglenks, Matthias, Schwenkglenks, Matthias, Zúñiga, Franziska, Vounatsou, Penelope, Quinto, Carlos, Blozik, Eva, Siqeca, Flaka, & Jara, Maria José Mendieta. (2021). A contextual analysis and logic model for integrated care for frail older adults living at home: The inspire project. International Journal of Integrated Care, 21. https://doi.org/10.5334/ijic.5607

Lawson D.O., Puljak L., Pieper D, Schandelmaier S, Collins GS, Brignardello-Petersen R, Moher D., Tugwell P, Welch VA, Samaan Z., Thombs BD, Norskov A.K., Jakobsen J.C., Allison D.B., Mayo-Wilson E, Young T., Chan AW, Briel M., Guyatt G.H., et al. (2020). Reporting of methodological studies in health research: a protocol for the development of the MethodologIcal STudy reportIng Checklist (MISTIC). BMJ Open, 10(12), e040478. https://doi.org/10.1136/bmjopen-2020-040478

Boulesteix A.-L., Groenwold R.H.H., Abrahamowicz M., Binder H., Briel M., Hornung R., Morris T.P., Rahnenfuhrer J., & Sauerbrei W. (2020). Introduction to statistical simulations in health research. BMJ Open, 10(12). https://doi.org/10.1136/bmjopen-2020-039921

Schünemann HJ, Ventresca M, Crowther M, Briel M, Zhou Q, Noble S, Macbeth F, Griffiths G, Garcia D, Lyman GH, Di Nisio M, Iorio A, Mbuagbaw L, Neumann I, van Es N, Brouwers M, Guyatt G, Streiff MB, Marcucci M, et al. (2020). Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis. The Lancet. Haematology, 7(10), e746–e755. https://doi.org/10.1016/s2352-3026(20)30293-3

Walter M.A., Spanjol M., Kollar A., Butikofer L., Gloy V.L., Dumont R.A., Seiler C.A., Christ E.R., Radojewski P., Briel M., & Kaderli R.M. (2020). Treatment for gastrointestinal and pancreatic neuroendocrine tumours: a network meta-analysis. Cochrane Database of Systematic Reviews, 2020(8). https://doi.org/10.1002/14651858.cd013700

Gloy V, McLennan S, Rinderknecht M, Ley B, Meier B, Driessen S, Gervasoni P, Hirschel B, Benkert P, Gilles I, von Elm E, & Briel M. (2020). Uncertainties about the need for ethics approval in Switzerland: a mixed-methods study. Swiss Medical Weekly, 150, w20318. https://doi.org/10.4414/smw.2020.20318

Schandelmaier S, Briel M, Varadhan R, Schmid CH, Devasenapathy N, Hayward RA, Gagnier J, Borenstein M, van der Heijden GJMG, Dahabreh IJ, Sun X, Sauerbrei W, Walsh M, Ioannidis JPA, Thabane L, & Guyatt GH. (2020). Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses. CMAJ : Canadian Medical Association Journal = Journal de l’Association Medicale Canadienne, 192(32), E901–E906. https://doi.org/10.1503/cmaj.200077

van Es N, Ventresca M, Di Nisio M, Zhou Q, Noble S, Crowther M, Briel M, Garcia D, Lyman GH, Macbeth F, Griffiths G, Iorio A, Mbuagbaw L, Neumann I, Brozek J, Guyatt G, Streiff MB, Baldeh T, Florez ID, et al. (2020). The Khorana score for prediction of venous thromboembolism in cancer patients: An individual patient data meta-analysis. Journal of Thrombosis and Haemostasis : JTH, 18(8), 1940–1951. https://doi.org/10.1111/jth.14824

Walter SD, Thabane L, & Briel M. (2020). The fragility of trial results involves more than statistical significance alone. Journal of Clinical Epidemiology, 124, 34–41. https://doi.org/10.1016/j.jclinepi.2020.02.011

Treweek S, & Briel M. (2020). Digital tools for trial recruitment and retention-plenty of tools but rigorous evaluation is in short supply. (Patent No. 1). 21(1), Article 1. https://doi.org/10.1186/s13063-020-04361-8

Odutayo A, Gryaznov D, Copsey B, Monk P, Speich B, Roberts C, Vadher K, Dutton P, Briel M, Hopewell S, Altman D.G., & ASPIRE study group . (2020). Design, analysis and reporting of multi-arm trials and strategies to address multiple testing. International Journal of Epidemiology, 49(3), 968–978. https://doi.org/10.1093/ije/dyaa026

Ventresca M, Schünemann HJ, Macbeth F, Clarke M, Thabane L, Griffiths G, Noble S, Garcia D, Marcucci M, Iorio A, Zhou Q, Crowther M, Akl EA, Lyman GH, Gloy V, DiNisio M, & Briel M. (2020). Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide. BMC Medical Research Methodology, 20(1), 113. https://doi.org/10.1186/s12874-020-00964-6

Treweek S, Jüni P, Li T, Collin J, Briel M, Chan AW, Hemming K, Meurer WJ, Sydes MR, & Grimshaw JM. (2020). COVID-19 randomised trial protocols: rapid publication without barriers. (Patent No. 1). 21(1), Article 1. https://doi.org/10.1186/s13063-020-04304-3

Speich B, Schroter S, Briel M, Moher D, Puebla I, Clark A, Maia Schlüssel M, Ravaud P, Boutron I, & Hopewell S. (2020). Impact of a short version of the CONSORT checklist for peer reviewers to improve the reporting of randomised controlled trials published in biomedical journals: study protocol for a randomised controlled trial. BMJ Open, 10(3), e035114. https://doi.org/10.1136/bmjopen-2019-035114

Walter SD, Han H, Guyatt GH, Bassler D, Bhatnagar N, Gloy V, Schandelmaier S, & Briel M. (2020). A systematic survey of randomised trials that stopped early for reasons of futility. BMC Medical Research Methodology, 20(1), 10. https://doi.org/10.1186/s12874-020-0899-1

Treweek S, Bevan S, Bower P, Briel M, Campbell M, Christie J, Collett C, Cotton S, Devane D, El Feky A, Galvin S, Gardner H, Gillies K, Hood K, Jansen J, Littleford R, Parker A, Ramsay C, Restrup L, et al. (2020). Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed. Trials, 21(1), 33. https://doi.org/10.1186/s13063-019-3980-5

Deschodt, Mieke, Laurent, Gwen, Cornelissen, Lonne, Yip, Olivia, Zúñiga, Franziska, Denhaerynck, Kris, Briel, Matthias, Karabegovic, Azra, De Geest, Sabina, & Inspire consortium. (2020). Core components and impact of nurse-led integrated care models for home-dwelling older people: A systematic review and meta-analysis. International Journal of Nursing Studies, 105, 103552. https://doi.org/10.1016/j.ijnurstu.2020.103552

Favaretto, Maddalena, De Clercq, Eva, Briel, Matthias, & Elger, Bernice Simone. (2020). Working Through Ethics Review of Big Data Research Projects: An Investigation into the Experiences of Swiss and American Researchers. Journal of Empirical Research on Human Research Ethics, 15(4), 339–354. https://doi.org/10.1177/1556264620935223

Gryaznov, D., Odutayo, A., von Niederhausern, B., Speich, B., Kasenda, B., Ojeda-Ruiz, E., Blumle, A., Schandelmaier, S., Mertz, D., Tomonaga, Y., Amstutz, A., Pauli-Magnus, C., Gloy, V., Bischoff, K., Wollmann, K., Rehner, L., Lohner, S., Meerpohl, J. J., Nordmann, A., et al. (2020). Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects. Trials, 21(1), 896. https://doi.org/10.1186/s13063-020-04808-y

Kasenda, Benjamin, Liu, Junhao, Jiang, Yu, Gajewski, Byron, Wu, Cen, von Elm, Erik, Schandelmaier, Stefan, Moffa, Giusi, Trelle, Sven, Schmitt, Andreas Michael, Herbrand, Amanda K., Gloy, Viktoria, Speich, Benjamin, Hopewell, Sally, Hemkens, Lars G., Sluka, Constantin, McGill, Kris, Meade, Maureen, Cook, Deborah, et al. (2020). Prediction of RECRUITment In Randomized Clinical Trials (RECRUIT-IT) - Rationale and Design for an International Collaborative Study. Trials, 21(1), 731. https://doi.org/10.1186/s13063-020-04666-8

Ladanie, Aviv, Schmitt, Andreas M., Speich, Benjamin, Naudet, Florian, Agarwal, Arnav, Pereira, Tiago V., Sclafani, Francesco, Herbrand, Amanda K., Briel, Matthias, Martin-Liberal, Juan, Schmid, Thomas, Ewald, Hannah, Ioannidis, John P. A., Bucher, Heiner C., Kasenda, Benjamin, & Hemkens, Lars G. (2020). Clinical trial evidence supporting US Food and Drug Administration approval of novel cancer therapies between 2000 and 2016. Jama Network Open, 3(11), e2024406. https://doi.org/10.1001/jamanetworkopen.2020.24406

Schandelmaier, Stefan, Chang, Yaping, Bala, Malgorzata M., Devasenapathy, Niveditha, Devji, Tahira, Kwong, Joey S. W., Colunga Lozano, Luis E., Lee, Yung, Agarwal, Arnav, Bhatnagar, Neera, Ewald, Hannah, Zhang, Ying, Sun, Xin, Thabane, Lehana, Walsh, Michael, Briel, Matthias, & Guyatt, Gordon H. (2020). Erratum to “A systematic survey identified 36 criteria for assessing effect modification claims in randomized trials or meta-analyses” [J Clin Epidemiol. 2019;113:159-67]. Journal of Clinical Epidemiology, 123, 189. https://doi.org/10.1016/j.jclinepi.2020.04.003

Schandelmaier, Stefan, Schmitt, Andreas M., Herbrand, Amanda K., Glinz, Dominik, Ewald, Hannah, Briel, Matthias, Guyatt, Gordon H., Hemkens, Lars G., & Kasenda, Benjamin. (2020). Characteristics and interpretation of subgroup analyses based on tumour characteristics in randomised trials testing target-specific anticancer drugs: design of a systematic survey. BMJ Open, 10(5), e034565. https://doi.org/10.1136/bmjopen-2019-034565

Speich, Benjamin, Gloy, Viktoria, Schur, Nadine, Ewald, Hannah, Hemkens, Lars G., Schwenkglenks, Matthias, Briel, Matthias, & MAking Randomized Trials Affordable Group. (2020). A scoping review shows that several nonvalidated budget planning tools for randomized trials are available. Journal of Clinical Epidemiology, 117, 9–19. https://doi.org/10.1016/j.jclinepi.2019.09.009

Schünemann HJ, Ventresca M, Crowther M, Briel M, Zhou Q, Noble S, Macbeth F, Griffiths G, Garcia D, Lyman G, DiNisio M, Iorio A, Beyene J, Mbuagbaw L, Neumann I, Van Es N, Brouwers M, Brozek J, Guyatt G, Moll S, et al. (2020). Individual participant data meta-analysis of 14 randomized trials evaluating prophylactic heparin in ambulatory cancer patients. Lancet Haematology , e746–e755.

Briel M, Speich B, von Elm E, & Gloy V. (2019). Comparison of randomized controlled trials discontinued or revised for poor recruitment and completed trials with the same research question: a matched qualitative study. Trials, 20(1), 800. https://doi.org/10.1186/s13063-019-3957-4

Kahale LA, Guyatt GH, Agoritsas T, Briel M, Busse JW, Carrasco-Labra A, Khamis AM, Zhang Y, Hooft L, Scholten RJPM, & Akl EA. (2019). A guidance was developed to identify participants with missing outcome data in randomized controlled trials. Journal of Clinical Epidemiology, 115, 55–63. https://doi.org/10.1016/j.jclinepi.2019.07.003

Ventresca, M., Schünemann, H. J., Macbeth, F., Clarke, M., Thabane, L., Griffiths, G., Noble, S., Garcia, D., Marcucci, M., Iorio, A., Zhou, Q., Crowther, M., Akl, E. A., Lyman, G. H., Gloy, V., Nisio, M. D., & Briel, M. (2019, October 22). Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.2.16277/v1

Treweek, S., Bevan, S., Bower, P., Briel, M., Campbell, M., Christie, J., Collett, C., Cotton, S., Devane, D., Feky, A. E., Galvin, S., Gardner, H., Gillies, K., Hood, K., Jansen, J., Littleford, R., Parker, A., Ramsay, C., Restrup, L., et al. (2019, October 9). Trial Forge Guidance 2: How to decide if a further Study Within A Trial (SWAT) is needed [Posted-content]. Research Square Platform LLC. https://doi.org/10.21203/rs.1.1/v2

Kernen P, Steveling-Klein EH, Saccilotto RT, Raatz H, Briel M, Koller MT, Westwood M, Bucher HC, Miedinger D, & Leuppi JD. (2019). The sensitivity and specificity of the mannitol bronchial challenge test to identify asthma in different populations: a systematic review. Swiss Medical Weekly, 149, w20100. https://doi.org/10.4414/smw.2019.20100

Walter SD, Guyatt GH, Bassler D, Briel M, Ramsay T, & Han HD. (2019). Randomised trials with provision for early stopping for benefit (or harm): The impact on the estimated treatment effect. Statistics in Medicine, 38(14), 2524–2543. https://doi.org/10.1002/sim.8142

Blum, Steffen, Meyre, Pascal, Aeschbacher, Stefanie, Berger, Sebastian, Auberson, Chloé, Briel, Matthias, Osswald, Stefan, & Conen, David. (2019). Incidence and predictors of atrial fibrillation progression: A systematic review and meta-analysis. Heart Rhythm, 16(4), 502–510. https://doi.org/10.1016/j.hrthm.2018.10.022

Kaderli RM, Spanjol M, Kollár A, Bütikofer L, Gloy V, Dumont RA, Seiler CA, Christ ER, Radojewski P, Briel M, & Walter MA. (2019). Therapeutic Options for Neuroendocrine Tumors: A Systematic Review and Network Meta-analysis. JAMA Oncology, 5(4), 480–489. https://doi.org/10.1001/jamaoncol.2018.6720

Blum, Claudine A., Schuetz, Philipp, Nigro, Nicole, Winzeler, Bettina, Arici, Birsen, Refardt, Julie, Urwyler, Sandrine A., Rodondi, Nicolas, Blum, Manuel R., Briel, Matthias, Müller, Beat, & Christ-Crain, Mirjam. (2019). Cosyntropin testing does not predict response to glucocorticoids in community-acquired pneumonia in a randomized controlled trial. Clinical Endocrinology, 91(3), 374–382. https://doi.org/10.1111/cen.13907

Herbrand, Amanda Katherina, Schmitt, Andreas Michael, Briel, Matthias, Diem, Stefan, Ewald, Hannah, Hoogkamer, Anouk, Joerger, Markus, Mc Cord, Kimberly Alba, Novak, Urban, Sricharoenchai, Sirintip, Hemkens, Lars G., & Kasenda, Benjamin. (2019). Contrasting evidence to reimbursement reality for off-label use (OLU) of drug treatments in cancer care: rationale and design of the CEIT-OLU project. ESMO Open, 4(6), e000596. https://doi.org/10.1136/esmoopen-2019-000596

Johnston B.C., Patrick D.L., Devji T., Maxwell L.J., Bingham C.O., Beaton D.E., Boers M., Briel M., Busse J.W., Carrasco-Labra A., Christensen R., Da Costa B.R., Dib R.E., Lyddiatt A., Ostelo R.W., Shea B., Singh J., Terwee C.B., Williamson P.R., et al. (2019). Patient-reported outcomes (pp. 479–492). wiley. https://doi.org/10.1002/9781119536604.ch18

Klatte, Katharina, Pauli-Magnus, Christiane, Love, Sharon, Sydes, Matthew, Benkert, Pascal, Bruni, Nicole, Ewald, Hannah, Arnaiz Jimenez, Patricia, Bonde, Marie Mi, & Briel, Matthias. (2019). Monitoring strategies for clinical intervention studies. Cochrane Database of Systematic Reviews, 2019(12). https://doi.org/10.1002/14651858.mr000051

Ladanie, Aviv, Speich, Benjamin, Briel, Matthias, Sclafani, Francesco, Bucher, Heiner C., Agarwal, Arnav, Ioannidis, John P. A., Pereira, Tiago V., Kasenda, Benjamin, & Hemkens, Lars G. (2019). Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies. Journal of Clinical Epidemiology, 114, 49–59. https://doi.org/10.1016/j.jclinepi.2019.05.033