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Prof. Dr. Catia Marzolini

Department of Clinical Research
Profiles & Affiliations

Publications

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Pham, Thao, Ghafoor, Mohamed, Grañana-Castillo, Sandra, Marzolini, Catia, Gibbons, Sara, Khoo, Saye, Chiong, Justin, Wang, Dennis, & Siccardi, Marco. (2024). DeepARV: ensemble deep learning to predict drug-drug interaction of clinical relevance with antiretroviral therapy [Journal-article]. npj Systems Biology and Applications, 10(1). https://doi.org/10.1038/s41540-024-00374-0

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Berton, Mattia, Stader, Felix, Bettonte, Sara, Battegay, Manuel, & Marzolini, Catia. (2024). Ideal Time to Conduct a Pharmacokinetic Investigation After Delivery to Fully Capture the Effect of Pregnancy on Drug Exposure [Journal-article]. Open Forum Infectious Diseases, 11(10), 11. https://doi.org/10.1093/ofid/ofae585

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Bettonte, Sara, Berton, Mattia, Stader, Felix, Battegay, Manuel, & Marzolini, Catia. (2024). Effect of Obesity on the Exposure of Long-acting Cabotegravir and Rilpivirine: A Modeling Study [Journal-article]. Clinical Infectious Diseases, 79(2), 477–486. https://doi.org/10.1093/cid/ciae060

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Bongiovanni, Marco, Thoueille, Paul, Barda, Beatrice, Mercier, Thomas, Marzolini, Catia, Ramponi, Niccolò, Choong, Eva, Cantù, Marco, Decosterd, Laurent A., & Bernasconi, Enos. (2024). Oritavancin use in patients with recurrent bone infections by methicillin-resistant Staphylococcus aureus with monitoring of concentrations [Journal-article]. European Journal of Clinical Microbiology and Infectious Diseases, 43(7), 1503–1504. https://doi.org/10.1007/s10096-024-04844-5

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Thoueille, Paul, Saldanha, Susana Alves, Schaller, Fabian, Choong, Eva, Veuve, François, Munting, Aline, Cavassini, Matthias, Braun, Dominique, Günthard, Huldrych F., Duran Ramirez, Jessy J., Surial, Bernard, Furrer, Hansjakob, Rauch, Andri, Ustero, Pilar, Calmy, Alexandra, Stöckle, Marcel, Di Benedetto, Caroline, Bernasconi, Enos, Schmid, Patrick, et al. (2024). Population Pharmacokinetics of Cabotegravir Following Oral Administration and Long-Acting Intramuscular Injection in Real-World People with HIV [Journal-article]. Clinical Pharmacology and Therapeutics, 115(6), 1450–1459. https://doi.org/10.1002/cpt.3240

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Bettonte, Sara, Berton, Mattia, Battegay, Manuel, Stader, Felix, & Marzolini, Catia. (2024). Development of a physiologically-based pharmacokinetic model to simulate the pharmacokinetics of intramuscular antiretroviral drugs [Journal-article]. CPT: Pharmacometrics and Systems Pharmacology, 13(5), 781–794. https://doi.org/10.1002/psp4.13118

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Bettonte, Sara, Berton, Mattia, Stader, Felix, Battegay, Manuel, & Marzolini, Catia. (2024). Drug Exposure of Long-Acting Cabotegravir and Rilpivirine in Older People With Human Immunodeficiency Virus: A Pharmacokinetic Modeling Study [Journal-article]. Open Forum Infectious Diseases, 11(4). https://doi.org/10.1093/ofid/ofae171

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Briki, M., Murisier, A., Guidi, M., Seydoux, C., Buclin, T., Marzolini, C., Girardin, F.R., Thoma, Y., Carrara, S., Choong, E., & Decosterd, L.A. (2024). Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) methods for the therapeutic drug monitoring of cytotoxic anticancer drugs: An update [Journal-article]. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1236, 124039. https://doi.org/10.1016/j.jchromb.2024.124039

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Thoueille, Paul, Delarive, Luc, Cavassini, Matthias, Buclin, Thierry, Decosterd, Laurent A., Marzolini, Catia, Girardin, François R., & Guidi, Monia. (2024). Population pharmacokinetic analysis of doravirine in real-world people with HIV. British Journal of Clinical Pharmacology, 90(4), 1058–1065. https://doi.org/10.1111/bcp.15975

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Ambrosioni, Juan, Díaz, Natalia Anahí, Marzolini, Catia, Dragovic, Gordana, Imaz, Arkaitz, Calcagno, Andrea, Luque, Sonia, Curran, Adrian, Troya, Jesus, Tuset, Montse, Khoo, Saye, Burger, David, Cortés, Claudia P., Naous, Nadia, & Molto, Jose. (2024). Outcomes of Drug Interactions Between Antiretrovirals and Co-Medications, Including Over-the-Counter Drugs: A Real-World Study. Infectious Diseases and Therapy, 13(3), 609–617. https://doi.org/10.1007/s40121-024-00935-0

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Thoueille, Paul, Cavassini, Matthias, Guidi, Monia, Buclin, Thierry, Girardin, François R., Decosterd, Laurent A., & Marzolini, Catia. (2024). Guidance for the Interpretation of Long-Acting Cabotegravir and Rilpivirine Concentrations Based on Real-World Therapeutic Drug Monitoring Data and Documented Failures. Open Forum Infectious Diseases, 11(2). https://doi.org/10.1093/ofid/ofae023

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Berton, Mattia, Bettonte, Sara, Stader, Felix, Decosterd, Laurent, Tarr, Philip E., Livio, Françoise, Cavassini, Matthias, Braun, Dominique L., Kusejko, Katharina, Hachfeld, Anna, Bernasconi, Enos, Calmy, Alexandra, Schmid, Patrick, Battegay, Manuel, & Marzolini, Catia. (2024). Antiretroviral Drug Exposure and Response in Obese and Morbidly Obese People With Human Immunodeficiency Virus (HIV): A Study Combining Modelling and Swiss HIV Cohort Data. Clinical Infectious Diseases, 78(1), 98–110. https://doi.org/10.1093/cid/ciad495

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Abela, Irene A, Chammartin, Frédérique, Amstutz, Alain, Surial, Bernard, Ballif, Marie, Marzolini, Catia, Aebi-Popp, Karoline, Notter, Julia, Segeral, Olivier, Stoeckle, Marcel, Cavassini, Matthias, Bernasconi, Enos, Günthard, Huldrych F, Kouyos, Roger D, & Pasin, Chloé. (2024). Gender Disparities in Statin Prescriptions in People With HIV With Low/Moderate to High Cardiovascular Risk. Open Forum Infectious Diseases, 11. https://doi.org/10.1093/ofid/ofae502

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Damas, José, Munting, Aline, Fellay, Jacques, Haerry, D., Marzolini, C., Tarr, Philip E., Steffen, Ana, Braun, Dominique L., Stoeckle, Marcel, Bernasconi, Enos, Nawej Tshikung, Olivier, Fux, C.A., Darling, Katharine E. A., Béguelin, Charles, Wandeler, G., Cavassini, Matthias, Surial, Bernard, Abela, I., Aebi-Popp, K., et al. (2024). Weight, Anthropometric and Metabolic Changes After Discontinuing Antiretroviral Therapy Containing Tenofovir Alafenamide in People With HIV [Journal-article]. Clinical Infectious Diseases, 79, 990–998. https://doi.org/10.1093/cid/ciae189

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Haefliger, David, Chehade, Hassib, Livio, Francoise, Rodrigues-Veiga, Viviane, Diezi, Léonore, & Marzolini, Catia. (2024). Vancomycin Dosing Strategy for the Treatment of Peritonitis in a Child on Automated Peritoneal Dialysis: A First Pediatric Case Report. Seminars in Dialysis. https://doi.org/10.1111/sdi.13224

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Marzolini, Catia, Gibbons, Sara, Seddon, Daniel, & Khoo, Saye. (2024). Drug-drug interactions potential with the HIV-1 capsid inhibitor lenacapavir. Expert Opinion on Drug Metabolism and Toxicology. https://doi.org/10.1080/17425255.2024.2415295

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Thoueille, Paul, Saldanha, Susana Alves, Schaller, Fabian, Choong, Eva, Munting, Aline, Cavassini, Matthias, Braun, Dominique, Günthard, Huldrych F., Kusejko, Katharina, Surial, Bernard, Furrer, Hansjakob, Rauch, Andri, Rougemont, Mathieu, Ustero, Pilar, Calmy, Alexandra, Stöckle, Marcel, Marzolini, Catia, Di Benedetto, Caroline, Bernasconi, Enos, et al. (2024). Real-world trough concentrations and effectiveness of long-acting cabotegravir and rilpivirine: a multicenter prospective observational study in Switzerland. The Lancet Regional Health - Europe, 36. https://doi.org/10.1016/j.lanepe.2023.100793

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Bettonte S, Berton M, Stader F, Battegay M, & Marzolini C. (2023). Intramuscular cabotegravir and rilpivirine concentrations after switching from efavirenz-containing regimen. British Journal of Clinical Pharmacology, 89(12), 3618–3628. https://doi.org/10.1111/bcp.15867

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Erba A, Marzolini C, Rentsch K, Stoeckle M, Battegay M, Mayr M, & Weisser M. (2023). Switch from a ritonavir to a cobicistat containing antiretroviral regimen and impact on tacrolimus levels in a kidney transplant recipient. Virology Journal, 20(1), 89. https://doi.org/10.1186/s12985-023-02058-3

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Ambrosioni, Juan, Levi, Laura, Alagaratnam, Jasmini, Van Bremen, Kathrin, Mastrangelo, Andrea, Waalewijn, Hylke, Molina, Jean-Michel, Guaraldi, Giovanni, Winston, Alan, Boesecke, Christoph, Cinque, Paola, Bamford, Alasdair, Calmy, Alexandra, Marzolini, Catia, Martínez, Esteban, Oprea, Cristiana, Welch, Steven, Koval, Anna, Mendao, Luis, & Rockstroh, Jürgen K. (2023). Major revision version 12.0 of the European AIDS Clinical Society guidelines 2023. HIV Medicine, 24(11), 1126–1136. https://doi.org/10.1111/hiv.13542

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Sebastiani G, Milic J, Tsochatzis EA, Marzolini C, Betel M, Bhagani S, Morse CG, Cinque F, Maurice JB, Ingiliz P, Price J, Lemoine M, Rockstroh JK, Guaraldi G, & Steatohepatitis in HIV Emerging Research (SHIVER) Network. (2023). Letter to the Editor: People living with HIV and NAFLD—A population left behind in the global effort for liver fibrosis screening? Hepatology, 78(5), E87–E88. https://doi.org/10.1097/HEP.0000000000000465

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Schwenke, Johannes M, Thorball, Christian W, Schoepf, Isabella C, Ryom, Lene, Hasse B., Lamy, Olivier, Calmy, Alexandra, Wandeler G., Marzolini C., Kahlert, Christian R, Bernasconi, Enos, Kouyos R.D., Günthard, Huldrych F, Ledergerber, Bruno, Fellay J., Burkhalter, Felix, Tarr, Philip E, Abela I., Aebi-Popp K., et al. (2023). Association of a Polygenic Risk Score With Osteoporosis in People Living With HIV: The Swiss HIV Cohort Study. Journal of Infectious Diseases, 228(6), 742–750. https://doi.org/10.1093/infdis/jiad179

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Marzolini C, Cavassini M, Braun DL, Hachfeld A, Bernasconi E, Calmy A, Schmid P, Battegay M, Elzi L, & Swiss HIV Cohort Study. (2023). Effect of SLCO1B1 c.521T> C polymorphism on the lipid response to statins in people living with HIV on a boosted protease inhibitor-containing regimen. British Journal of Clinical Pharmacology, 89(9), 2739–2746. https://doi.org/10.1111/bcp.15754

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Berton M, Bettonte S, Stader F, Battegay M, & Marzolini C. (2023). Impact of Obesity on the Drug-Drug Interaction Between Dolutegravir and Rifampicin or Any Other Strong Inducers. Open Forum Infectious Diseases, 10(7), ofad361. https://doi.org/10.1093/ofid/ofad361

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Bettonte S, Berton M, Stader F, Battegay M, & Marzolini C. (2023). Management of Drug Interactions with Inducers: Onset and Disappearance of Induction on Cytochrome P450 3A4 and Uridine Diphosphate Glucuronosyltransferase 1A1 Substrates. European Journal of Drug Metabolism and Pharmacokinetics, 48(4), 353–362. https://doi.org/10.1007/s13318-023-00833-9

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Haefliger D, Marzolini C, Lamoth F, Pabst T, Buclin T, & Livio F. (2023). Clinically relevant bidirectional drug-drug interaction between midostaurin and voriconazole (Patent No. 7). 89(7), Article 7. https://doi.org/10.1111/bcp.15743

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Avery Emma F, Kleynhans Julia N, Ledergerber Bruno, Schoepf Isabella C, Thorball Christian W, Kootstra Neeltje A, Reiss Peter, Ryom Lene, Braun Dominique L, Thurnheer Maria C, Marzolini Catia, Seneghini Marco, Bernasconi Enos, Cavassini Matthias, Buvelot Hélène, Kouyos Roger D, Fellay Jacques, Günthard Huldrych F, & Tarr Philip E. (2023). Leukocyte Count and Coronary Artery Disease Events in People with Human Immunodeficiency Virus: A Longitudinal Study. Clinical Infectious Diseases, 76(11), 1969–1979. https://doi.org/10.1093/cid/ciad033

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Avery, Emma F, Kleynhans, Julia N, Ledergerber, Bruno, Schoepf, Isabella C, Thorball, Christian W, Kootstra, Neeltje A, Reiss, Peter, Ryom, Lene, Braun, Dominique L, Thurnheer, Maria C, Marzolini, Catia, Seneghini, Marco, Bernasconi, Enos, Cavassini, Matthias, Buvelot, Hélène, Kouyos, Roger D, Fellay, Jacques, Günthard, Huldrych F, Tarr, Philip E, et al. (2023). Leukocyte Count and Coronary Artery Disease Events in People with Human Immunodeficiency Virus: A Longitudinal Study [Journal-article]. Clinical Infectious Diseases, 76(11), 1969–1979. https://doi.org/10.1093/cid/ciad033

Schoepf, Isabella C, Esteban-Cantos, Andrés, Thorball, Christian W, Rodés, Berta, Reiss, Peter, Rodríguez-Centeno, Javier, Riebensahm, Carlotta, Braun, Dominique L, Marzolini, Catia, Seneghini, Marco, Bernasconi, Enos, Cavassini, Matthias, Buvelot, Hélène, Thurnheer, Maria Christine, Kouyos, Roger D, Fellay, Jacques, Günthard, Huldrych F, Arribas, José R, Ledergerber, Bruno, & Tarr, Philip E. (2023). Epigenetic ageing accelerates before antiretroviral therapy and decelerates after viral suppression in people with HIV in Switzerland: a longitudinal study over 17 years. The Lancet Healthy Longevity, 4(5), e211–e218. https://doi.org/10.1016/S2666-7568(23)00037-5

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Schoepf, Isabella C, Esteban-Cantos, Andrés, Thorball, Christian W, Rodés, Berta, Reiss, Peter, Rodríguez-Centeno, Javier, Riebensahm, Carlotta, Braun, Dominique L, Marzolini, Catia, Seneghini, Marco, Bernasconi, Enos, Cavassini, Matthias, Buvelot, Hélène, Thurnheer, Maria Christine, Kouyos, Roger D, Fellay, Jacques, Günthard, Huldrych F, Arribas, José R, Ledergerber, Bruno, & Tarr, Philip E. (2023). Epigenetic ageing accelerates before antiretroviral therapy and decelerates after viral suppression in people with HIV in Switzerland: a longitudinal study over 17 years [Journal-article]. The Lancet Healthy Longevity, 4(5), e211–e218. https://doi.org/10.1016/s2666-7568(23)00037-5

Bettonte S, Berton M, Stader F, Battegay M, & Marzolini C. (2023). Management of Drug-Drug Interactions between Long-Acting Cabotegravir and Rilpivirine and Comedications with Inducing Properties: A Modeling Study. Clinical Infectious Diseases, 76(7), 1225–1236. https://doi.org/10.1093/cid/ciac901

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Marzolini C, & Khoo S. (2023). Response to “A Case Report of Safe Coadministration of Amioradone With Short-Term Treatment Nirmatrelvir-Ritonavir” (Patent No. 4). 113(4), Article 4. https://doi.org/10.1002/cpt.2809

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Berton M, Bettonte S, Stader F, Battegay M, & Marzolini C. (2023). Physiologically Based Pharmacokinetic Modelling to Identify Physiological and Drug Parameters Driving Pharmacokinetics in Obese Individuals. Clinical Pharmacokinetics, 62(2), 277–295. https://doi.org/10.1007/s40262-022-01194-3

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Hodge, Daryl, Hodel, Eva Maria, Hughes, Elen, Hazenberg, Phoebe, Grañana Castillo, Sandra, Gibbons, Sara, Wang, Duolao, Marra, Fiona, Marzolini, Catia, Back, David, & Khoo, Saye. (2023). Prevalence of Potentially Clinically Significant Drug-Drug Interactions with Antiretrovirals Against HIV over Three Decades: A Systematic Review of the Literature [Journal-article]. Journal of Acquired Immune Deficiency Syndromes, 92(2), 97–105. https://doi.org/10.1097/QAI.0000000000003122

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Bettonte S, Berton M, & Marzolini C. (2023). What is the significance of the pharmacokinetic profile and potential drug–drug interactions of long-acting intramuscular cabotegravir and rilpivirine? (Patent No. 5). 19(5), Article 5. https://doi.org/10.1080/17425255.2023.2223961

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Thoueille, P., Alves Saldanha, S., Schaller, F., Choong, E., Munting, A., Cavassini, M., Braun, D., Günthard, H. F., Kusejko, K., Surial, B., Furrer, H., Rauch, A., Rougemont, M., Ustero, P., Calmy, A., Stoeckle, M., Marzolini, C., Di Benedetto, C., Bernasconi, E., et al. (2023). Real-World Trough Concentrations and Effectiveness of Long-Acting Cabotegravir and Rilpivirine: A Multicenter Prospective Observational Study in Switzerland [Posted-content]. Elsevier BV. https://doi.org/10.2139/ssrn.4584084

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Aebi-Popp K, Kahlert CR, Crisinel PA, Decosterd L, Saldanha SA, Hoesli I, Martinez De Tejada B, Duppenthaler A, Rauch A, Marzolini C, & Swiss Mother and Child HIV Cohort Study (SHCS). (2022). Transfer of antiretroviral drugs into breastmilk: a prospective study from the Swiss Mother and Child HIV Cohort Study. Journal of Antimicrobial Chemotherapy, 77(12), 3436–3442. https://doi.org/10.1093/jac/dkac337

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Marzolini C, Kuritzkes DR, Marra F, Boyle A, Gibbons S, Flexner C, Pozniak A, Boffito M, Waters L, Burger D, Back DJ, & Khoo S. (2022). Recommendations for the Management of Drug–Drug Interactions Between the COVID-19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications. Clinical Pharmacology and Therapeutics, 112(6), 1191–1200. https://doi.org/10.1002/cpt.2646

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Berton M, Bettonte S, Stader F, Battegay M, & Marzolini C. (2022). Repository Describing the Anatomical, Physiological, and Biological Changes in an Obese Population to Inform Physiologically Based Pharmacokinetic Models. Clinical Pharmacokinetics, 61(9), 1251–1270. https://doi.org/10.1007/s40262-022-01132-3

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Franchini F, Kusejko K, Marzolini C, Tellenbach C, Rossi S, Stampf S, Koller M, Stoyanov J, Möller B, & Leichtle AB. (2022). Collaborative Challenges of Multi-Cohort Projects in Pharmacogenetics—Why Time Is Essential for Meaningful Collaborations. JMIR Formative Research, 6(9), e36759. https://doi.org/10.2196/36759

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Jakeman, Bernadette, Scherrer, Alexandra U., Darling, Katharine E.A., Damas, Jose, Bieler-Aeschlimann, Melanie, Hasse, Barbara, Schlosser, Ladina, Hachfeld, Anna, Gutbrod, Klemens, Tarr, Philip E., Calmy, Alexandra, Assal, Frederic, Kunze, Ursula, Stoeckle, Marcel, Schmid, Patrick, Toller, Gianina, Rossi, Stefania, di Benedetto, Caroline, du Pasquier, Renaud, et al. (2022). Anticholinergic and Sedative Medications Are Associated With Neurocognitive Performance of Well Treated People With Human Immunodeficiency Virus. Open Forum Infectious Diseases, 9(9). https://doi.org/10.1093/ofid/ofac457

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Ryom L, De Miguel R, Cotter AG, Podlekareva D, Beguelin C, Waalewijn H, Arribas JR, Mallon PWG, Marzolini C, Kirk O, Bamford A, Rauch A, Molina JM, Kowalska JD, Guaraldi G, Winston A, Boesecke C, Cinque P, Welch S, et al. (2022). Major revision version 11.0 of the European AIDS Clinical Society Guidelines 2021. HIV Medicine, 23(8), 849–858. https://doi.org/10.1111/hiv.13268

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Girardin F, Manuel O, Marzolini C, & Buclin T. (2022). Evaluating the risk of drug-drug interactions with pharmacokinetic boosters: the case of ritonavir-enhanced nirmatrelvir to prevent severe COVID-19. Clinical Microbiology and Infection, 28(8), 1044–1046. https://doi.org/10.1016/j.cmi.2022.03.030

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Thoueille P, Alves Saldanha S, Schaller F, Munting A, Cavassini M, Braun D, Günthard HF, Kusejko K, Surial B, Furrer H, Rauch A, Ustero P, Calmy A, Stoeckle M, Battegay M, Marzolini C, Andre P, Guidi M, Buclin T, et al. (2022). Real-Life Therapeutic Concentration Monitoring of Long-Acting Cabotegravir and Rilpivirine: Preliminary Results of an Ongoing Prospective Observational Study in Switzerland. Pharmaceutics, 14(8). https://doi.org/10.3390/pharmaceutics14081588

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Otten LS, Piet B, van den Heuvel MM, Marzolini C, van Geel RMJM, Gulikers JL, Burger DM, Leentjens J, & Ter Heine R. (2022). Practical recommendations to combine small-molecule inhibitors and direct oral anticoagulants in patients with nonsmall cell lung cancer. European Respiratory Review, 31(164). https://doi.org/10.1183/16000617.0004-2022

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Stader F, & Marzolini C. (2022). Sex-related pharmacokinetic differences with aging. European Geriatric Medicine, 13(3), 559–565. https://doi.org/10.1007/s41999-021-00587-0

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Marzolini C, Kuritzkes DR, Marra F, Boyle A, Gibbons S, Flexner C, Pozniak A, Boffito M, Waters L, Burger D, Back D, & Khoo S. (2022). Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions (Patent No. 5). 175(5), Article 5. https://doi.org/10.7326/M22-0281

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Schoepf, Isabella C., Thorball, Christian W., Ledergerber, Bruno, Kootstra, Neeltje A., Reiss, Peter, Raffenberg, Marieke, Engel, Tanja, Braun, Dominique L., Hasse, Barbara, Thurnheer, Christine, Marzolini, Catia, Seneghini, Marco, Bernasconi, Enos, Cavassini, Matthias, Buvelot, Hélène, Arribas, José R., Kouyos, Roger D., Fellay, Jacques, Günthard, Huldrych F., & Tarr, Philip E. (2022). Telomere Length Declines in Persons With Human Immunodeficiency Virus Before Antiretroviral Therapy Start but Not After Viral Suppression: A Longitudinal Study Over > 17 Years. Journal of Infectious Diseases, 225(9), 1581–1591. https://doi.org/10.1093/infdis/jiab603

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Zino L, Kingma JS, Marzolini C, Richel O, Burger DM, & Colbers A. (2022). Implications of Bariatric Surgery on the Pharmacokinetics of Antiretrovirals in People Living with HIV. Clinical Pharmacokinetics, 61(5), 619–635. https://doi.org/10.1007/s40262-022-01120-7

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Bettonte S, Berton M, & Marzolini C. (2022). Magnitude of Drug–Drug Interactions in Special Populations. Pharmaceutics, 14(4). https://doi.org/10.3390/pharmaceutics14040789

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Jacobs TG, Marzolini C, Back DJ, & Burger DM. (2022). Dexamethasone is a dose-dependent perpetrator of drug-drug interactions: Implications for use in people living with HIV. Journal of Antimicrobial Chemotherapy, 77(3), 568–573. https://doi.org/10.1093/jac/dkab412

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Marzolini C, Gibbons S, van Oosterhout JJ, & Khoo S. (2022). Drug–Drug Interaction Potential with Once-Weekly Isoniazid/Rifapentine (3HP) for the Treatment of Latent Tuberculosis Infection. Clinical Pharmacokinetics, 61(3), 339–346. https://doi.org/10.1007/s40262-021-01098-8

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Marzolini C, Marra F, Boyle A, Khoo S, & Back DJ. (2022). Fluvoxamine for the treatment of COVID-19 (Patent No. 3). 10(3), Article 3. https://doi.org/10.1016/S2214-109X(21)00592-1

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Stader F, Battegay M, Sendi P, & Marzolini C. (2022). Physiologically Based Pharmacokinetic Modelling to Investigate the Impact of the Cytokine Storm on CYP3A Drug Pharmacokinetics in COVID-19 Patients. Clinical Pharmacology and Therapeutics, 111(3), 579–584. https://doi.org/10.1002/cpt.2402

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Jakeman B, Scherrer A, Battegay M, Gunthard HF, Hachfeld A, Calmy A, Schmid P, Bernasconi E, Cavassini M, & Marzolini C. (2022). Anticholinergic medication use in elderly people living with HIV and self-reported neurocognitive impairment: A prospective cohort study. Journal of Antimicrobial Chemotherapy, 77(2), 492–499. https://doi.org/10.1093/jac/dkab386

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Scherrer AU, Traytel A, Braun DL, Calmy A, Battegay M, Cavassini M, Furrer H, Schmid P, Bernasconi E, Stoeckle M, Kahlert C, Trkola A, Kouyos RD, Tarr P, Marzolini C, Wandeler G, Fellay J, Bucher H, Yerly S, et al. (2022). Cohort Profile Update: The Swiss HIV Cohort Study (SHCS). International Journal of Epidemiology, 51(1), 33–34J. https://doi.org/10.1093/ije/dyab141

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Schoepf IC, Thorball CW, Ledergerber B, Engel T, Raffenberg M, Kootstra NA, Reiss P, Hasse B, Marzolini C, Thurnheer C, Seneghini M, Bernasconi E, Cavassini M, Buvelot H, Kouyos R, Günthard HF, Fellay J, Tarr PE, & Swiss HIV Cohort Study. (2021). Coronary artery disease-associated and longevity-associated polygenic risk scores for prediction of coronary artery disease events in persons living with human immunodeficiency virus: The swiss hiv cohort study. Clinical Infectious Diseases, 73(9), 1597–1604. https://doi.org/10.1093/cid/ciab521

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Stader F, Battegay M, & Marzolini C. (2021). Physiologically-Based Pharmacokinetic Modeling to Support the Clinical Management of Drug–Drug Interactions With Bictegravir. Clinical Pharmacology and Therapeutics, 110(5), 1231–1239. https://doi.org/10.1002/cpt.2221

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Allavena C, & Marzolini C. (2021). Polypharmacy and risk of admission to hospital in people ageing with HIV: what is the contribution of drug–drug interactions? (Patent No. 10). 2(10), Article 10. https://doi.org/10.1016/S2666-7568(21)00227-0

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Courlet P, Guidi M, Alves Saldanha S, Cavassini M, Stoeckle M, Buclin T, Marzolini C, Decosterd LA, & Csajka C. (2021). Population pharmacokinetic modelling to quantify the magnitude of drug-drug interactions between amlodipine and antiretroviral drugs. European Journal of Clinical Pharmacology, 77(7), 979–987. https://doi.org/10.1007/s00228-020-03060-2

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Hodge D, Back DJ, Gibbons S, Khoo SH, & Marzolini C. (2021). Pharmacokinetics and Drug–Drug Interactions of Long-Acting Intramuscular Cabotegravir and Rilpivirine. Clinical Pharmacokinetics, 60(7), 835–853. https://doi.org/10.1007/s40262-021-01005-1

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Stader F, Courlet P, Decosterd LA, Battegay M, & Marzolini C. (2021). Physiologically-Based Pharmacokinetic Modeling Combined with Swiss HIV Cohort Study Data Supports No Dose Adjustment of Bictegravir in Elderly Individuals Living With HIV. Clinical Pharmacology and Therapeutics, 109(4), 1025–1029. https://doi.org/10.1002/cpt.2178

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Courlet P, Guidi M, Alves Saldanha S, Stader F, Traytel A, Cavassini M, Stoeckle M, Buclin T, Marzolini C, Decosterd LA, Csajka C, & and the Swiss HIV Cohort Study. (2021). Pharmacokinetic/Pharmacodynamic Modelling to Describe the Cholesterol Lowering Effect of Rosuvastatin in People Living with HIV. Clinical Pharmacokinetics, 60(3), 379–390. https://doi.org/10.1007/s40262-020-00946-3

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Marra F, Smolders EJ, El-Sherif O, Boyle A, Davidson K, Sommerville AJ, Marzolini C, Siccardi M, Burger D, Gibbons S, Khoo S, & Back D. (2021). Recommendations for Dosing of Repurposed COVID-19 Medications in Patients with Renal and Hepatic Impairment. Drugs in R and D, 21(1), 9–27. https://doi.org/10.1007/s40268-020-00333-0

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Marzolini C, Stader F, Leuppi-Taegtmeyer A, Stoeckle M, Battegay M, & Sendi P. (2021). Sex Differences in Lopinavir Concentrations and Occurrence of Marked QTc Prolongation Episodes in Patients with COVID-19 (Patent No. 2). 44(2), Article 2. https://doi.org/10.1007/s40264-020-01025-z

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Back, David, Marzolini, Catia, Hodge, Catherine, Marra, Fiona, Boyle, Alison, Gibbons, Sara, Burger, David, & Khoo, Saye. (2021). COVID-19 treatment in patients with comorbidities: Awareness of drug-drug interactions. British Journal of Clinical Pharmacology, 87(1), 212–213. https://doi.org/10.1111/bcp.14358

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Deutschmann, Elisabeth, Bucher, Heiner C., Jaeckel, Steffen, Gibbons, Sara, McAllister, Katie, Scherrer, Alexandra U., Braun, Dominique L., Cavassini, Matthias, Hachfeld, Anna, Calmy, Alexandra, Battegay, Manuel, Cipriani, Michela, Elzi, Luigia, Young, James, Lopez-Centeno, Beatriz, Berenguer, Juan, Khoo, Saye, Moffa, Giusi, Marzolini, Catia, & Swiss HIV Cohort Study. (2021). Prevalence of Potential Drug-Drug Interactions in Patients of the Swiss HIV Cohort Study in the Era of HIV Integrase Inhibitors. Clinical Infectious Diseases, 73(7), e2145–e2152. https://doi.org/10.1093/cid/ciaa918

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Hollinger, Alexa, Cueni, Nadine, Marzolini, Catia, Dickenmann, Michael, Landmann, Emmanuelle, Battegay, Manuel, Martinez, Aurélien Emmanuel, Siegemund, Martin, & Leuppi-Taegtmeyer, Anne. (2021). Lactic acidosis and hyperlactatemia associated with lamivudine accumulation and sepsis in a kidney transplant recipient—a case report and review of the literature. AIDS Research and Therapy, 18. https://doi.org/10.1186/s12981-021-00382-8

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Istampoulouoglou I, Zimmermanns B, Grandinetti T, Marzolini C, Harings-Kaim A, Koechlin-Lemke S, Scholz I, Bassetti S, & Leuppi-Taegtmeyer AB. (2021). Cardiovascular adverse effects of lopinavir/ritonavir and hydroxychloroquine in COVID-19 patients: Cases from a single pharmacovigilance centre. Global Cardiology Science and Practice, 2021(2), e202111. https://doi.org/10.21542/GCSP.2021.11

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Kümmerle, A., Sikalengo, G., Vanobberghen, F., Ndege, R. C., Foe, G., Schlaeppi, C., Burri, C., Battegay, M., Paris, D. H., Glass, T. R., Weisser, M., Marzolini, C., & Kiularco Study Group. (2021). Recognition and management of clinically significant drug-drug interactions between antiretrovirals and co-medications in a cohort of people living with HIV in rural Tanzania: a prospective questionnaire-based study. J Antimicrob Chemother, 76(10), 2681–2689. https://doi.org/10.1093/jac/dkab254

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Mari, Alfredo, Roloff, Tim, Stange, Madlen, Søgaard, Kirstine K., Asllanaj, Erblin, Tauriello, Gerardo, Alexander, Leila Tamara, Schweitzer, Michael, Leuzinger, Karoline, Gensch, Alexander, Martinez, Aurélien E., Bielicki, Julia, Pargger, Hans, Siegemund, Martin, Nickel, Christian H., Bingisser, Roland, Osthoff, Michael, Bassetti, Stefano, Sendi, Parham, et al. (2021). Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance. Microorganisms, 9(5), 1094. https://doi.org/10.3390/microorganisms9051094

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Marzolini, Catia, Battegay, Manuel, Sendi, Parham, & Back, David J. (2021). Prescribing in COVID-19 patients: Should we take into account inflammation? British Journal of Clinical Pharmacology, 87(3), 719–721. https://doi.org/10.1111/bcp.14524

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Roth, Jan A., Radevski, Gorjan, Marzolini, Catia, Rauch, Andri, Günthard, Huldrych F., Kouyos, Roger D., Fux, Christoph A., Scherrer, Alexandra U., Calmy, Alexandra, Cavassini, Matthias, Kahlert, Christian R., Bernasconi, Enos, Bogojeska, Jasmina, & Battegay, Manuel. (2021). Cohort-derived machine learning models for individual prediction of chronic kidney disease in people living with Human Immunodeficiency Virus: a prospective multicentre cohort study. Journal of Infectious Diseases, 224(7), 1198–1208. https://doi.org/10.1093/infdis/jiaa236

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Stader, Felix, Courlet, Perrine, Kinvig, Hannah, Battegay, Manuel, Decosterd, Laurent A., Penny, Melissa A., Siccardi, Marco, & Marzolini, Catia. (2021). Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation. British Journal of Clinical Pharmacology, 87(2), 458–470. https://doi.org/10.1111/bcp.14402

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Stader, Felix, Courlet, Perrine, Kinvig, Hannah, Penny, Melissa A., Decosterd, Laurent A., Battegay, Manuel, Siccardi, Marco, & Marzolini, Catia. (2021). Clinical Data Combined With Modeling and Simulation Indicate Unchanged Drug-Drug Interaction Magnitudes in the Elderly. Clinical Pharmacology & Therapeutics, 109(2), 471–484. https://doi.org/10.1002/cpt.2017

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Allavena C, & Marzolini C. (2021). Polypharmacy and risk of admission to hospital in people ageing with HIV: what is the contribution of drug-drug interactions? Lancet Healthy Longev, 2.

Surial, Bernard, Ledergerber, Bruno, Calmy, Alexandra, Cavassini, Matthias, Günthard, Huldrych F., Kovari, Helen, Stöckle, Marcel, Bernasconi, Enos, Schmid, Patrick, Fux, Christoph A., Furrer, Hansjakob, Rauch, Andri, Wandeler, Gilles, Anagnostopoulos A., Battegay M., Boni J., Braun D.L., Bucher H.C., Ciuffi A., et al. (2020). Changes in renal function after switching from TDF to TAF in HIV-infected individuals: A prospective cohort study. Journal of Infectious Diseases, 222(4), 637–645. https://doi.org/10.1093/infdis/jiaa125

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Marzolini, C., Stader, F., Stoeckle, M., Franzeck, F., Egli, A., Bassetti, S., Hollinger, A., Osthoff, M., Weisser, M., Gebhard, C. E., Baettig, V., Geenen, J., Khanna, N., Tschudin-Sutter, S., Mueller, D., Hirsch, H. H., Battegay, M., & Sendi, P. (2020, July 7). Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2020.07.05.20146878

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Back, David, & Marzolini, Catia. (2020). The challenge of HIV treatment in an era of polypharmacy. Journal of the International AIDS Society, 23(2), e25449. https://doi.org/10.1002/jia2.25449

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Bukkems, Vera E., Colbers, Angela, Marzolini, Catia, Molto, Jose, & Burger, David M. (2020). Drug-Drug Interactions with Antiretroviral Drugs in Pregnant Women Living with HIV: Are They Different from Non-Pregnant Individuals? Clinical Pharmacokinetics, 59(10), 1217–1236. https://doi.org/10.1007/s40262-020-00914-x

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Burger, David M., Calmy, Alexandra, & Marzolini, Catia. (2020). Cobicistat: A case of mislabelled drug-drug interaction risk? British Journal of Clinical Pharmacology, 86(5), 834–836. https://doi.org/10.1111/bcp.14262

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Courlet, Perrine, Alves Saldanha, Susana, Cavassini, Matthias, Marzolini, Catia, Choong, Eva, Csajka, Chantal, Günthard, Huldrych F., André, Pascal, Buclin, Thierry, Desfontaine, Vincent, & Decosterd, Laurent Arthur. (2020). Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV. Journal of Mass Spectrometry, 55(6), e4506. https://doi.org/10.1002/jms.4506

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Courlet, Perrine, Decosterd, Laurent A., Alves Saldanha, Susana, Cavassini, Matthias, Stader, Felix, Stoeckle, Marcel, Buclin, Thierry, Marzolini, Catia, Csajka, Chantal, Guidi, Monia, & Swiss HIV Cohort Study. (2020). Influence of Drug-Drug Interactions on the Pharmacokinetics of Atorvastatin and Its Major Active Metabolite ortho-OH-Atorvastatin in Aging People Living with HIV. Clinical Pharmacokinetics, 59(8), 1037–1048. https://doi.org/10.1007/s40262-020-00876-0

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Courlet, Perrine, Livio, Françoise, Alves Saldanha, Susana, Scherrer, Alexandra, Battegay, Manuel, Cavassini, Matthias, Stoeckle, Marcel, Decosterd, Laurent Arthur, Marzolini, Catia, & Swiss HIV Cohort Study. (2020). Real-life management of drug-drug interactions between antiretrovirals and statins. The Journal of Antimicrobial Chemotherapy, 75(7), 1972–1980. https://doi.org/10.1093/jac/dkaa099

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Guaraldi, Giovanni, Maurice, James B., Marzolini, Catia, Monteith, Kenneth, Milic, Jovana, Tsochatzis, Emmanuel, Bhagani, Sanjay, Morse, Caryn G., Price, Jennifer C., Ingiliz, Patrick, Lemoine, Maud, Sebastiani, Giada, & Shiver Network. (2020). New Drugs for NASH and HIV Infection: Great Expectations for a Great Need. Hepatology, 71(5), 1831–1844. https://doi.org/10.1002/hep.31177

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Hodge, Catherine, Marra, Fiona, Marzolini, Catia, Boyle, Alison, Gibbons, Sara, Siccardi, Marco, Burger, David, Back, David, & Khoo, Saye. (2020). Drug interactions: a review of the unseen danger of experimental COVID-19 therapies. The Journal of Antimicrobial Chemotherapy, 75(12), 3417–3424. https://doi.org/10.1093/jac/dkaa340

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Livio, Françoise, Deutschmann, Elisabeth, Moffa, Giusi, Rrustemi, Flamur, Stader, Felix, Elzi, Luigia, Braun, Dominique L., Calmy, Alexandra, Hachfeld, Anna, Cavassini, Matthias, Tarr, Philip E., Wissel, Kerstin, Battegay, Manuel, Marzolini, Catia, & Swiss HIV Cohort Study. (2020). Analysis of inappropriate prescribing in elderly patients of the Swiss HIV Cohort Study reveals gender inequity. The Journal of Antimicrobial Chemotherapy, dkaa505. https://doi.org/10.1093/jac/dkaa505

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López-Centeno, Beatriz, Badenes-Olmedo, Carlos, Mataix-Sanjuan, Ángel, Bellón, José M., Pérez-Latorre, Leire, López, J. C., Benedí, Juana, Khoo, Saye, Marzolini, Catia, Calvo-Alcántara, María J., & Berenguer, Juan. (2020). Potentially inappropriate medications in older adults living with HIV. HIV Medicine, 21(8), 541–546. https://doi.org/10.1111/hiv.12883

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Marzolini, Catia, Stader, Felix, Stoeckle, Marcel, Franzeck, Fabian, Egli, Adrian, Bassetti, Stefano, Hollinger, Alexa, Osthoff, Michael, Weisser, Maja, Gebhard, Caroline E., Baettig, Veronika, Geenen, Julia, Khanna, Nina, Tschudin-Sutter, Sarah, Müller, Daniel, Hirsch, Hans H., Battegay, Manuel, & Sendi, Parham. (2020). Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations. Antimicrobial Agents and Chemotherapy, 64(9), e01177–20. https://doi.org/10.1128/aac.01177-20

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Ryom, L., Cotter, A., De Miguel, R., Béguelin, Charles, Podlekareva, D., Arribas, J. R., Marzolini, Catia, Mallon, Pgm, Rauch, A., Kirk, Ole, Molinari, Jesus M., Guaraldi, G., Winston, A., Bhagani, S., Cinque, Paola, Kowalska, Joanna D., Collins, S., Battegay, Manuel, & Eacs Governing Board. (2020). 2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0. HIV Medicine, 21(10), 617–624. https://doi.org/10.1111/hiv.12878

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Stader, Felix, Decosterd, Laurent, Stoeckle, Marcel, Cavassini, Matthias, Battegay, Manuel, Saldanha, Susana Alves, Marzolini, Catia, Courlet, Perrine, & The Swiss HIV Cohort Study. (2020). Aging does not impact drug--drug interaction magnitudes with antiretrovirals. Aids, 34(6), 949–952. https://doi.org/10.1097/qad.0000000000002489

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Stader, Felix, Khoo, Saye, Stoeckle, Marcel, Back, David, Hirsch, Hans H., Battegay, Manuel, & Marzolini, Catia. (2020). Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect. The Journal of Antimicrobial Chemotherapy, 75(10), 3084–3086. https://doi.org/10.1093/jac/dkaa253

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Courlet, Perrine, Livio, Françoise, Guidi, Monia, Cavassini, Matthias, Battegay, Manuel, Stoeckle, Marcel, Buclin, Thierry, Saldanha, Susana Alves, Csajka, Chantal, Marzolini, C., Decosterd, Laurent, Anagnostopoulos, A., Battegay, M., Bernasconi, E., Böni, J., Braun, D.L., Bucher, H.C., Calmy, A., Cavassini, M., et al. (2019). Polypharmacy, drug–drug interactions, and inappropriate drugs: New challenges in the aging population with HIV. Open Forum Infectious Diseases, 6(12). https://doi.org/10.1093/ofid/ofz531

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Barcelo C., Aouri M., Courlet P., Guidi M., Braun D.L., Gunthard H.F., Piso R.J., Cavassini M., Buclin T., Decosterd L.A., Csajka C., Anagnostopoulos A., Battegay M., Bernasconi E., Boni J., Braun D.L., Bucher H.C., Calmy A., Cavassini M., et al. (2019). Population pharmacokinetics of dolutegravir: Influence of drug-drug interactions in a real-life setting. Journal of Antimicrobial Chemotherapy, 74(9), 2690–2697. https://doi.org/10.1093/jac/dkz217

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Boyle, Alison, Moss, Catherine E., Marzolini, Catia, & Khoo, Saye. (2019). Clinical Pharmacodynamics, Pharmacokinetics, and Drug Interaction Profile of Doravirine. Clinical Pharmacokinetics, 58(12), 1553–1565. https://doi.org/10.1007/s40262-019-00806-9

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Brockhaus, Lisa, Goldblum, David, Eggenschwiler, Laura, Zimmerli, Stefan, & Marzolini, Catia. (2019). Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics. Clinical microbiology and infection, NA. https://doi.org/10.1016/j.cmi.2019.01.017

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Courlet, Perrine, Decosterd, Laurent Arthur, Brown, Jennifer Anne, Alves Saldanha, Susana, Marzolini, Catia, Cavassini, Matthias, Stoeckle, Marcel, Csajka, Chantal, Labhardt, Niklaus Daniel, Calmy, Alexandra, & Swiss HIV Cohort Study,. (2019). Emtricitabine and lamivudine concentrations in saliva : a simple suitable test for treatment adherence. Journal of Antimicrobial Chemotherapy, 74(8), 2468–2470. https://doi.org/10.1093/jac/dkz181

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Courlet, Perrine, Guidi, Monia, Glatard, Anaïs, Alves Saldanha, Susana, Cavassini, Matthias, Buclin, Thierry, Marzolini, Catia, Eap, Chin B., Decosterd, Laurent A., Csajka, Chantal, & Swiss HIV Cohort Study. (2019). Escitalopram population pharmacokinetics in people living with human immunodeficiency virus and in the psychiatric population: Drug-drug interactions and probability of target attainment. British Journal of Clinical Pharmacology, 85(9), 2022–2032. https://doi.org/10.1111/bcp.13994

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Courlet, Perrine, Livio, Françoise, Guidi, Monia, Cavassini, Matthias, Battegay, Manuel, Stoeckle, Marcel, Buclin, Thierry, Alves Saldanha, Susana, Csajka, Chantal, Marzolini, Catia, Decosterd, Laurent, & Swiss HIV Cohort Study. (2019). Polypharmacy, Drug-Drug Interactions, and Inappropriate Drugs: New Challenges in the Aging Population With HIV. Open Forum Infectious Diseases, 6(12), ofz531. https://doi.org/10.1093/ofid/ofz531

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Courlet, Perrine, Spaggiari, Dany, Desfontaine, Vincent, Cavassini, Matthias, Alves Saldanha, Susana, Buclin, Thierry, Marzolini, Catia, Csajka, Chantal, & Decosterd, Laurent-Arthur. (2019). UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV. Journal of Chromatography B, 1125, 121733. https://doi.org/10.1016/j.jchromb.2019.121733

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