Publications
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Verouti, S., Aeschlimann, G., Wang, Q., Del Olmo, D. A., Peyter, A. C., Menétrey, S., Winter, D. V., , Pearce, D., Hummler, E., & Vanderriele, P. E. (2024). Salt-sensitive hypertension in GR mutant rats is associated with altered plasma polyunsaturated fatty acid levels and aortic vascular reactivity [Journal-article]. Pflügers Archiv - European Journal of Physiology. https://doi.org/10.1007/s00424-024-03014-y
Verouti, S., Aeschlimann, G., Wang, Q., Del Olmo, D. A., Peyter, A. C., Menétrey, S., Winter, D. V., , Pearce, D., Hummler, E., & Vanderriele, P. E. (2024). Salt-sensitive hypertension in GR mutant rats is associated with altered plasma polyunsaturated fatty acid levels and aortic vascular reactivity [Journal-article]. Pflügers Archiv - European Journal of Physiology. https://doi.org/10.1007/s00424-024-03014-y
Gómez, C., Alimajstorovic, Z., Othonos, N., Winter, D. V., White, S., Lavery, G. G., Tomlinson, J. W., Sinclair, A. J., & Odermatt, A. (2024). Identification of a human blood biomarker of pharmacological 11β-hydroxysteroid dehydrogenase 1 inhibition. British Journal of Pharmacology, 181(5), 698–711. https://doi.org/10.1111/bph.16251
Gómez, C., Alimajstorovic, Z., Othonos, N., Winter, D. V., White, S., Lavery, G. G., Tomlinson, J. W., Sinclair, A. J., & Odermatt, A. (2024). Identification of a human blood biomarker of pharmacological 11β-hydroxysteroid dehydrogenase 1 inhibition. British Journal of Pharmacology, 181(5), 698–711. https://doi.org/10.1111/bph.16251
Kędzierski, Jacek, Jäger, Marie-Christin, Naeem, Sadaf, , & Smieško, Martin. (2024). In silico and in vitro assessment of drugs potentially causing adverse effects by inhibiting CYP17A1. Toxicology and Applied Pharmacology, 486. https://doi.org/10.1016/j.taap.2024.116945
Kędzierski, Jacek, Jäger, Marie-Christin, Naeem, Sadaf, , & Smieško, Martin. (2024). In silico and in vitro assessment of drugs potentially causing adverse effects by inhibiting CYP17A1. Toxicology and Applied Pharmacology, 486. https://doi.org/10.1016/j.taap.2024.116945
Kolesnyk, Serhii, Prodanchuk, Mykola, Zhminko, Petro, Kolianchuk, Yana, Bubalo, Nataliia, , & Smieško, Martin. (2023). A battery of in silico models application for pesticides exerting reproductive health effects: Assessment of performance and prioritization of mechanistic studies [Journal-article]. Toxicology in Vitro, 93, 105706. https://doi.org/10.1016/j.tiv.2023.105706
Kolesnyk, Serhii, Prodanchuk, Mykola, Zhminko, Petro, Kolianchuk, Yana, Bubalo, Nataliia, , & Smieško, Martin. (2023). A battery of in silico models application for pesticides exerting reproductive health effects: Assessment of performance and prioritization of mechanistic studies [Journal-article]. Toxicology in Vitro, 93, 105706. https://doi.org/10.1016/j.tiv.2023.105706
Jäger, Marie-Christin, Kędzierski, Jacek, Gell, Victoria, Wey, Tim, Kollár, Jakub, Winter, Denise V., Schuster, Daniela, Smieško, Martin, & . (2023). Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase [Journal-article]. Toxicology and Applied Pharmacology, 475, 116638. https://doi.org/10.1016/j.taap.2023.116638
Jäger, Marie-Christin, Kędzierski, Jacek, Gell, Victoria, Wey, Tim, Kollár, Jakub, Winter, Denise V., Schuster, Daniela, Smieško, Martin, & . (2023). Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase [Journal-article]. Toxicology and Applied Pharmacology, 475, 116638. https://doi.org/10.1016/j.taap.2023.116638
Szabo, Leonora, Cummins, Nadia, Paganetti, Paolo, , Papassotiropoulos, Andreas, Karch, Celeste, Götz, Jürgen, Eckert, Anne, & Grimm, Amandine. (2023). ER-mitochondria contacts and cholesterol metabolism are disrupted by disease-associated tau protein. EMBO Reports, 24(8). https://doi.org/10.15252/embr.202357499
Szabo, Leonora, Cummins, Nadia, Paganetti, Paolo, , Papassotiropoulos, Andreas, Karch, Celeste, Götz, Jürgen, Eckert, Anne, & Grimm, Amandine. (2023). ER-mitochondria contacts and cholesterol metabolism are disrupted by disease-associated tau protein. EMBO Reports, 24(8). https://doi.org/10.15252/embr.202357499
Kędzierski, Jacek, Allard, Julien A., , & Smieško, Martin. (2023). Assessment of the inhibitory potential of anabolic steroids towards human AKR1D1 by computational methods and in vitro evaluation [Journal-article]. Toxicology Letters, 384, 1–13. https://doi.org/10.1016/j.toxlet.2023.07.006
Kędzierski, Jacek, Allard, Julien A., , & Smieško, Martin. (2023). Assessment of the inhibitory potential of anabolic steroids towards human AKR1D1 by computational methods and in vitro evaluation [Journal-article]. Toxicology Letters, 384, 1–13. https://doi.org/10.1016/j.toxlet.2023.07.006
Jäger, Marie-Christin, Patt, Melanie, González-Ruiz, Víctor, Boccard, Julien, Wey, Tim, Winter, Denise V, Rudaz, Serge, & . (2023). Extended steroid profiling in H295R cells provides deeper insight into chemical-induced disturbances of steroidogenesis: Exemplified by prochloraz and anabolic steroids. Molecular and Cellular Endocrinology, 570, 111929. https://doi.org/10.1016/j.mce.2023.111929
Jäger, Marie-Christin, Patt, Melanie, González-Ruiz, Víctor, Boccard, Julien, Wey, Tim, Winter, Denise V, Rudaz, Serge, & . (2023). Extended steroid profiling in H295R cells provides deeper insight into chemical-induced disturbances of steroidogenesis: Exemplified by prochloraz and anabolic steroids. Molecular and Cellular Endocrinology, 570, 111929. https://doi.org/10.1016/j.mce.2023.111929
Bolten, Jan Stephan, Mancuso, Riccardo Vincenzo, Roos, Noëmi Johanna, Mayr, Aline, Puligilla, Ramya Deepthi, Kraus, Lisa, , Fricker, Gert, & Huwyler, Jörg. (2023). Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models. Toxicology and Applied Pharmacology, 466(446), 116493. https://doi.org/10.1016/j.taap.2023.116493
Bolten, Jan Stephan, Mancuso, Riccardo Vincenzo, Roos, Noëmi Johanna, Mayr, Aline, Puligilla, Ramya Deepthi, Kraus, Lisa, , Fricker, Gert, & Huwyler, Jörg. (2023). Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models. Toxicology and Applied Pharmacology, 466(446), 116493. https://doi.org/10.1016/j.taap.2023.116493
Bourqui, Laurent, Winter, Denise V, , Loffing-Cueni, Dominique, & Loffing, Johannes. (2023). A novel mouse model for an inducible gene modification in the renal thick ascending limb. American Journal of Physiology - Renal Physiology, 324(5), F446–F460. https://doi.org/10.1152/ajprenal.00250.2022
Bourqui, Laurent, Winter, Denise V, , Loffing-Cueni, Dominique, & Loffing, Johannes. (2023). A novel mouse model for an inducible gene modification in the renal thick ascending limb. American Journal of Physiology - Renal Physiology, 324(5), F446–F460. https://doi.org/10.1152/ajprenal.00250.2022
Ben Rhouma, Bochra, Kley, Manuel, Kallabi, Fakhri, Kacem, Faten Hadj, Kammoun, Thouraya, Safi, Wajdi, Keskes, Leila, Mnif, Mouna, , & Belguith, Neila. (2023). Molecular mechanisms underlying the defects of two novel mutations in the HSD17B3 gene found in the Tunisian population. Journal of Steroid Biochemistry and Molecular Biology, 227, 106235. https://doi.org/10.1016/j.jsbmb.2022.106235
Ben Rhouma, Bochra, Kley, Manuel, Kallabi, Fakhri, Kacem, Faten Hadj, Kammoun, Thouraya, Safi, Wajdi, Keskes, Leila, Mnif, Mouna, , & Belguith, Neila. (2023). Molecular mechanisms underlying the defects of two novel mutations in the HSD17B3 gene found in the Tunisian population. Journal of Steroid Biochemistry and Molecular Biology, 227, 106235. https://doi.org/10.1016/j.jsbmb.2022.106235
Berber, M., Leng, S., Wengi, A., Winter, D. V., Odermatt, A., Beuschlein, F., Loffing, J., Breault, D. T., & Penton, D. (2023). Calcineurin regulates aldosterone production via dephosphorylation of NFATC4. JCI Insight, 8(14). https://doi.org/10.1172/jci.insight.157027
Berber, M., Leng, S., Wengi, A., Winter, D. V., Odermatt, A., Beuschlein, F., Loffing, J., Breault, D. T., & Penton, D. (2023). Calcineurin regulates aldosterone production via dephosphorylation of NFATC4. JCI Insight, 8(14). https://doi.org/10.1172/jci.insight.157027
Geueke, Birgit, Groh, Ksenia J, Maffini, Maricel V, Martin, Olwenn V, Boucher, Justin M, Chiang, Yu-Ting, Gwosdz, Frank, Jieh, Phoenix, Kassotis, Christopher D, Łańska, Paulina, Myers, John Peterson, , Parkinson, Lindsey V, Schreier, Verena N, Srebny, Vanessa, Zimmermann, Lisa, Scheringer, Martin, & Muncke, Jane. (2023). Systematic evidence on migrating and extractable food contact chemicals: Most chemicals detected in food contact materials are not listed for use. Critical Reviews in Food Science and Nutrition, 63(28), 9425–9435. https://doi.org/10.1080/10408398.2022.2067828
Geueke, Birgit, Groh, Ksenia J, Maffini, Maricel V, Martin, Olwenn V, Boucher, Justin M, Chiang, Yu-Ting, Gwosdz, Frank, Jieh, Phoenix, Kassotis, Christopher D, Łańska, Paulina, Myers, John Peterson, , Parkinson, Lindsey V, Schreier, Verena N, Srebny, Vanessa, Zimmermann, Lisa, Scheringer, Martin, & Muncke, Jane. (2023). Systematic evidence on migrating and extractable food contact chemicals: Most chemicals detected in food contact materials are not listed for use. Critical Reviews in Food Science and Nutrition, 63(28), 9425–9435. https://doi.org/10.1080/10408398.2022.2067828
Jäger, M.-C., Joos, F. L., Winter, D. V., & Odermatt, A. (2023). Characterization of the interferences of systemic azole antifungal drugs with adrenal steroid biosynthesis using H295R cells and enzyme activity assays. Current Research in Toxicology, 5. https://doi.org/10.1016/j.crtox.2023.100119
Jäger, M.-C., Joos, F. L., Winter, D. V., & Odermatt, A. (2023). Characterization of the interferences of systemic azole antifungal drugs with adrenal steroid biosynthesis using H295R cells and enzyme activity assays. Current Research in Toxicology, 5. https://doi.org/10.1016/j.crtox.2023.100119
Schreier, Verena N., Çörek, Emre, Appenzeller-Herzog, Christian, Brüschweiler, Beat J., Geueke, Birgit, Wilks, Martin F., Schilter, Benoit, Muncke, Jane, Simat, Thomas J., Smie�ko, Martin, Roth, Nicolas, & . (2023). Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: A systematic evidence map. Environment international, 176, 107978. https://doi.org/10.1016/j.envint.2023.107978
Schreier, Verena N., Çörek, Emre, Appenzeller-Herzog, Christian, Brüschweiler, Beat J., Geueke, Birgit, Wilks, Martin F., Schilter, Benoit, Muncke, Jane, Simat, Thomas J., Smie�ko, Martin, Roth, Nicolas, & . (2023). Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: A systematic evidence map. Environment international, 176, 107978. https://doi.org/10.1016/j.envint.2023.107978
Schreier, V. N., Odermatt, A., & Welle, F. (2023). Migration Modeling as a Valuable Tool for Exposure Assessment and Risk Characterization of Polyethylene Terephthalate Oligomers. Molecules, 28(1). https://doi.org/10.3390/molecules28010173
Schreier, V. N., Odermatt, A., & Welle, F. (2023). Migration Modeling as a Valuable Tool for Exposure Assessment and Risk Characterization of Polyethylene Terephthalate Oligomers. Molecules, 28(1). https://doi.org/10.3390/molecules28010173
Meier DT, Rachid L, Wiedemann SJ, Traub S, Trimigliozzi K, Stawiski M, Sauteur L, Winter DV, Le Foll C, Brégère C, Guzman R, , Böni-Schnetzler M, & Donath MY. (2022). Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing. Nature Communications, 13(1), 4761. https://doi.org/10.1038/s41467-022-32509-4
Meier DT, Rachid L, Wiedemann SJ, Traub S, Trimigliozzi K, Stawiski M, Sauteur L, Winter DV, Le Foll C, Brégère C, Guzman R, , Böni-Schnetzler M, & Donath MY. (2022). Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing. Nature Communications, 13(1), 4761. https://doi.org/10.1038/s41467-022-32509-4
Stücheli S, Araya S, Ercan C, Moser SO, Gallon J, Jenö P, Piscuoglio S, Terracciano L, & . (2022). The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples. Cancers, 14(13). https://doi.org/10.3390/cancers14133074
Stücheli S, Araya S, Ercan C, Moser SO, Gallon J, Jenö P, Piscuoglio S, Terracciano L, & . (2022). The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples. Cancers, 14(13). https://doi.org/10.3390/cancers14133074
Stücheli, Simon, Araya, Selene, Ercan, Caner, Moser, Seraina O, Gallon, John, Jenö, Paul, Piscuoglio, Salvatore, Terracciano, Luigi, & . (2022). The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples. Cancers, 14(13), 3074. https://doi.org/10.3390/cancers14133074
Stücheli, Simon, Araya, Selene, Ercan, Caner, Moser, Seraina O, Gallon, John, Jenö, Paul, Piscuoglio, Salvatore, Terracciano, Luigi, & . (2022). The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples. Cancers, 14(13), 3074. https://doi.org/10.3390/cancers14133074
Stücheli, Simon, Araya, Selene, Ercan, Caner, Moser, Seraina O., Gallon, John, Jenö, Paul, Piscuoglio, Salvatore, Terracciano, Luigi, & . (2022). The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples [Journal-article]. Cancers, 14(13), 3074. https://doi.org/10.3390/cancers14133074
Stücheli, Simon, Araya, Selene, Ercan, Caner, Moser, Seraina O., Gallon, John, Jenö, Paul, Piscuoglio, Salvatore, Terracciano, Luigi, & . (2022). The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples [Journal-article]. Cancers, 14(13), 3074. https://doi.org/10.3390/cancers14133074
Inderbinen, Silvia G, Kley, Manuel, Zogg, Michael, Sellner, Manuel, Fischer, André, Kędzierski, Jacek, Boudon, Stéphanie, Jetten, Anton M, Smiesko, Martin, & . (2022). Activation of retinoic acid-related orphan receptor γ(t) by parabens and benzophenone UV-filters. Toxicology, 471, 153159. https://doi.org/10.1016/j.tox.2022.153159
Inderbinen, Silvia G, Kley, Manuel, Zogg, Michael, Sellner, Manuel, Fischer, André, Kędzierski, Jacek, Boudon, Stéphanie, Jetten, Anton M, Smiesko, Martin, & . (2022). Activation of retinoic acid-related orphan receptor γ(t) by parabens and benzophenone UV-filters. Toxicology, 471, 153159. https://doi.org/10.1016/j.tox.2022.153159
Leclercq, Gabrielle, Haegel, Hélène, Toso, Alberto, Zimmermann, Tina, Green, Luke, Steinhoff, Nathalie, Sam, Johannes, Pulko, Vesna, Schneider, Anneliese, Giusti, Anna Maria, Challier, John, Freimoser-Grundschober, Anne, Larivière, Laurent, , Stern, Martin, Umana, Pablo, Bacac, Marina, & Klein, Christian. (2022). JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy. Journal for ImmunoTherapy of Cancer, 10(1), e003766. https://doi.org/10.1136/jitc-2021-003766
Leclercq, Gabrielle, Haegel, Hélène, Toso, Alberto, Zimmermann, Tina, Green, Luke, Steinhoff, Nathalie, Sam, Johannes, Pulko, Vesna, Schneider, Anneliese, Giusti, Anna Maria, Challier, John, Freimoser-Grundschober, Anne, Larivière, Laurent, , Stern, Martin, Umana, Pablo, Bacac, Marina, & Klein, Christian. (2022). JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy. Journal for ImmunoTherapy of Cancer, 10(1), e003766. https://doi.org/10.1136/jitc-2021-003766
Gathercole, Laura L, Nikolaou, Nikolaos, Harris, Shelley E, Arvaniti, Anastasia, Poolman, Toryn M, Hazlehurst, Jonathan M, Kratschmar, Denise V, Todorčević, Marijana, Moolla, Ahmad, Dempster, Niall, Pink, Ryan C, Saikali, Michael F, Bentley, Liz, Penning, Trevor M, Ohlsson, Claes, Cummins, Carolyn L, Poutanen, Matti, , Cox, Roger D, & Tomlinson, Jeremy W. (2022). AKR1D1 knockout mice develop a sex-dependent metabolic phenotype. Journal of Endocrinology, 253(3), 97–113. https://doi.org/10.1530/JOE-21-0280
Gathercole, Laura L, Nikolaou, Nikolaos, Harris, Shelley E, Arvaniti, Anastasia, Poolman, Toryn M, Hazlehurst, Jonathan M, Kratschmar, Denise V, Todorčević, Marijana, Moolla, Ahmad, Dempster, Niall, Pink, Ryan C, Saikali, Michael F, Bentley, Liz, Penning, Trevor M, Ohlsson, Claes, Cummins, Carolyn L, Poutanen, Matti, , Cox, Roger D, & Tomlinson, Jeremy W. (2022). AKR1D1 knockout mice develop a sex-dependent metabolic phenotype. Journal of Endocrinology, 253(3), 97–113. https://doi.org/10.1530/JOE-21-0280
Keppner, Anna, Correia, Miguel, Santambrogio, Sara, Koay, Teng Wei, Maric, Darko, Osterhof, Carina, Winter, Denise V, Clerc, Angèle, Stumpe, Michael, Chalmel, Frédéric, Dewilde, Sylvia, , Kressler, Dieter, Hankeln, Thomas, Wenger, Roland H, & Hoogewijs, David. (2022). Androglobin, a chimeric mammalian globin, is required for male fertility. eLife, 11, 72374. https://doi.org/10.7554/eLife.72374
Keppner, Anna, Correia, Miguel, Santambrogio, Sara, Koay, Teng Wei, Maric, Darko, Osterhof, Carina, Winter, Denise V, Clerc, Angèle, Stumpe, Michael, Chalmel, Frédéric, Dewilde, Sylvia, , Kressler, Dieter, Hankeln, Thomas, Wenger, Roland H, & Hoogewijs, David. (2022). Androglobin, a chimeric mammalian globin, is required for male fertility. eLife, 11, 72374. https://doi.org/10.7554/eLife.72374
Leclercq, Gabrielle, Servera, Llucia Alberti, Danilin, Sabrina, Challier, John, Steinhoff, Nathalie, Bossen, Claudia, , Nicolini, Valeria, Umaña, Pablo, Klein, Christian, Bacac, Marina, Giusti, Anna-Maria, Schneider, Anneliese, & Haegel, Hélène. (2022). Dissecting the mechanism of cytokine release induced by T-cell engagers highlights the contribution of neutrophils. OncoImmunology, 11(1), 2039432. https://doi.org/10.1080/2162402X.2022.2039432
Leclercq, Gabrielle, Servera, Llucia Alberti, Danilin, Sabrina, Challier, John, Steinhoff, Nathalie, Bossen, Claudia, , Nicolini, Valeria, Umaña, Pablo, Klein, Christian, Bacac, Marina, Giusti, Anna-Maria, Schneider, Anneliese, & Haegel, Hélène. (2022). Dissecting the mechanism of cytokine release induced by T-cell engagers highlights the contribution of neutrophils. OncoImmunology, 11(1), 2039432. https://doi.org/10.1080/2162402X.2022.2039432
Meier, Daniel T, Rachid, Leila, Wiedemann, Sophia J, Traub, Shuyang, Trimigliozzi, Kelly, Stawiski, Marc, Sauteur, Loïc, Winter, Denise V, Le Foll, Christelle, Brégère, Catherine, Guzman, Raphael, , Böni-Schnetzler, Marianne, & Donath, Marc Y. (2022). Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing. Nature Communications, 13(1), 4761. https://doi.org/10.1038/s41467-022-32509-4
Meier, Daniel T, Rachid, Leila, Wiedemann, Sophia J, Traub, Shuyang, Trimigliozzi, Kelly, Stawiski, Marc, Sauteur, Loïc, Winter, Denise V, Le Foll, Christelle, Brégère, Catherine, Guzman, Raphael, , Böni-Schnetzler, Marianne, & Donath, Marc Y. (2022). Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing. Nature Communications, 13(1), 4761. https://doi.org/10.1038/s41467-022-32509-4
Schreier, Verena N., Appenzeller-Herzog, Christian, Brüschweiler, Beat J., Geueke, Birgit, Wilks, Martin F., Simat, Thomas J., Schilter, Benoit, Smiesko, Martin, Muncke, Jane, , & Roth, Nicolas. (2022). Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: Protocol for a systematic evidence map. Environment International, 167, 107387. https://doi.org/10.1016/j.envint.2022.107387
Schreier, Verena N., Appenzeller-Herzog, Christian, Brüschweiler, Beat J., Geueke, Birgit, Wilks, Martin F., Simat, Thomas J., Schilter, Benoit, Smiesko, Martin, Muncke, Jane, , & Roth, Nicolas. (2022). Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: Protocol for a systematic evidence map. Environment International, 167, 107387. https://doi.org/10.1016/j.envint.2022.107387
Weingartner, Michael, Stücheli, Simon, Jebbawi, Fadi, Gottstein, Bruno, Beldi, Guido, Lundström-Stadelmann, Britta, Wang, Junhua, & . (2022). Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection. PLoS Neglected Tropical Diseases, 16(1), e0009192. https://doi.org/10.1371/JOURNAL.PNTD.0009192
Weingartner, Michael, Stücheli, Simon, Jebbawi, Fadi, Gottstein, Bruno, Beldi, Guido, Lundström-Stadelmann, Britta, Wang, Junhua, & . (2022). Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection. PLoS Neglected Tropical Diseases, 16(1), e0009192. https://doi.org/10.1371/JOURNAL.PNTD.0009192
Lemmens, Myriam, Fischer, Benoit, Zogg, Michael, Rodrigues, Lindsey, Kerr, Grainne, Del Rio-Espinola, Alberto, Schaeffer, Fanny, Maddalo, Danilo, Dubost, Valerie, Piaia, Alessandro, Müller, Arne, Plappert-Helbig, Ulla, Naumann, Ulrike, Haegele, Jasmin, , Martus, Hans-Jörg, & Libertini, Silvana. (2021). Evaluation of two in vitro assays for tumorigenicity assessment of CRISPR-Cas9 genome-edited cells. Molecular Therapy Methods and Clinical Development, 23, 241–253. https://doi.org/10.1016/j.omtm.2021.09.004
Lemmens, Myriam, Fischer, Benoit, Zogg, Michael, Rodrigues, Lindsey, Kerr, Grainne, Del Rio-Espinola, Alberto, Schaeffer, Fanny, Maddalo, Danilo, Dubost, Valerie, Piaia, Alessandro, Müller, Arne, Plappert-Helbig, Ulla, Naumann, Ulrike, Haegele, Jasmin, , Martus, Hans-Jörg, & Libertini, Silvana. (2021). Evaluation of two in vitro assays for tumorigenicity assessment of CRISPR-Cas9 genome-edited cells. Molecular Therapy Methods and Clinical Development, 23, 241–253. https://doi.org/10.1016/j.omtm.2021.09.004
Vanderriele, Paul-Emmanuel, Wang, Qing, Mérillat, Anne-Marie, Ino, Frédérique, Aeschlimann, Gilles, Ehret, Xavier, Ancin Del Olmo, David, Ponce de León, Verónica, Scholl, Ute I, Winter, Denise V, , Hummler, Edith, & Verouti, Sophia N. (2021). Salt-sensitive hypertension in gr+/− rats is accompanied with dysregulation in adrenal soluble epoxide hydrolase and polyunsaturated fatty acid pathways. International Journal of Molecular Sciences, 22(24), 13218. https://doi.org/10.3390/ijms222413218
Vanderriele, Paul-Emmanuel, Wang, Qing, Mérillat, Anne-Marie, Ino, Frédérique, Aeschlimann, Gilles, Ehret, Xavier, Ancin Del Olmo, David, Ponce de León, Verónica, Scholl, Ute I, Winter, Denise V, , Hummler, Edith, & Verouti, Sophia N. (2021). Salt-sensitive hypertension in gr+/− rats is accompanied with dysregulation in adrenal soluble epoxide hydrolase and polyunsaturated fatty acid pathways. International Journal of Molecular Sciences, 22(24), 13218. https://doi.org/10.3390/ijms222413218
Morris, D. J., Brem, A. S., & Odermatt, A. (2021). Modulation of 11β-hydroxysteroid dehydrogenase functions by the cloud of endogenous metabolites in a local microenvironment: The glycyrrhetinic acid-like factor (GALF) hypothesis. Journal of Steroid Biochemistry and Molecular Biology, 214. https://doi.org/10.1016/j.jsbmb.2021.105988
Morris, D. J., Brem, A. S., & Odermatt, A. (2021). Modulation of 11β-hydroxysteroid dehydrogenase functions by the cloud of endogenous metabolites in a local microenvironment: The glycyrrhetinic acid-like factor (GALF) hypothesis. Journal of Steroid Biochemistry and Molecular Biology, 214. https://doi.org/10.1016/j.jsbmb.2021.105988
Banki, Eszter, Fisi, Viktoria, Moser, Sandra, Wengi, Agnieszka, Carrel, Monique, Loffing-Cueni, Dominique, Penton, David, Kratschmar, Denise V, Rizzo, Ludovica, Lienkamp, Soeren, , Rinschen, Markus M, & Loffing, Johannes. (2021). Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis. Kidney International, 100(4), 850–869. https://doi.org/10.1016/j.kint.2021.06.030
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Crane, Erika A., Heydenreuter, Wolfgang, Beck, Katharina R., Strajhar, Petra, Vomacka, Jan, Smiesko, Martin, Mons, Elma, Barth, Lydia, Neuburger, Markus, Vedani, Angelo, , Sieber, Stephan A., & Gademann, Karl. (2019). Profiling withanolide A for therapeutic targets in neurodegenerative diseases. Bioorganic & Medicinal Chemistry, 27(12), 2508–2520. https://doi.org/10.1016/j.bmc.2019.03.022
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Egli, Jerome, Schlothauer, Tilman, Spick, Christian, Seeber, Stefan, Singer, Thomas, , & Iglesias, Antonio. (2019). The Binding of Human IgG to Minipig FcγRs - Implications for Preclinical Assessment of Therapeutic Antibodies. Pharmaceutical Research, 36(3), 47. https://doi.org/10.1007/s11095-019-2574-y
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Egli, Jerome, Schmucki, Roland, Loos, Benjamin, Reichl, Stephan, Grabole, Nils, Roller, Andreas, Ebeling, Martin, , & Iglesias, Antonio. (2019). The genomic organization and expression pattern of the low-affinity Fc gamma receptors (FcγR) in the Göttingen minipig. Immunogenetics, 71(2), 123–136. https://doi.org/10.1007/s00251-018-01099-1
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Keppner, Anna, Maric, Darko, Sergi, Chloé, Ansermet, Camille, De Bellis, Damien, Kratschmar, Denise V., Canonica, Jérémie, Klusonova, Petra, Fenton, Robert A., , Crambert, Gilles, Hoogewijs, David, & Hummler, Edith. (2019). Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion. Scientific Reports, 9(1), 19540. https://doi.org/10.1038/s41598-019-55995-x
Keppner, Anna, Maric, Darko, Sergi, Chloé, Ansermet, Camille, De Bellis, Damien, Kratschmar, Denise V., Canonica, Jérémie, Klusonova, Petra, Fenton, Robert A., , Crambert, Gilles, Hoogewijs, David, & Hummler, Edith. (2019). Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion. Scientific Reports, 9(1), 19540. https://doi.org/10.1038/s41598-019-55995-x
Sandström, Jenny, Kratschmar, Denise V., Broyer, Alexandra, Poirot, Olivier, Marbet, Philippe, Chantong, Boonrat, Zufferey, Fanny, Dos Santos, Tania, Boccard, Julien, Chrast, Roman, , & Monnet-Tschudi, Florianne. (2019). In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice. Archives of Toxicology, 93, 1649–1664. https://doi.org/10.1007/s00204-019-02455-0
Sandström, Jenny, Kratschmar, Denise V., Broyer, Alexandra, Poirot, Olivier, Marbet, Philippe, Chantong, Boonrat, Zufferey, Fanny, Dos Santos, Tania, Boccard, Julien, Chrast, Roman, , & Monnet-Tschudi, Florianne. (2019). In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice. Archives of Toxicology, 93, 1649–1664. https://doi.org/10.1007/s00204-019-02455-0
Strajhar, Petra, Vizeli, Patrick, Patt, Melanie, Dolder, Patrick C., Kratschmar, Denise V., Liechti, Matthias E., & . (2019). Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study. Journal of Steroid Biochemistry and Molecular Biology, 186, 212–225. https://doi.org/10.1016/j.jsbmb.2018.10.016
Strajhar, Petra, Vizeli, Patrick, Patt, Melanie, Dolder, Patrick C., Kratschmar, Denise V., Liechti, Matthias E., & . (2019). Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study. Journal of Steroid Biochemistry and Molecular Biology, 186, 212–225. https://doi.org/10.1016/j.jsbmb.2018.10.016
Thompson, George R., Beck, Katharina R., Patt, Melanie, Kratschmar, Denise V., & . (2019). Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2. Journal of the Endocrine Society, 3(7), 1361–1366. https://doi.org/10.1210/js.2019-00189
Thompson, George R., Beck, Katharina R., Patt, Melanie, Kratschmar, Denise V., & . (2019). Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2. Journal of the Endocrine Society, 3(7), 1361–1366. https://doi.org/10.1210/js.2019-00189
Trinh, Beckey, Hepprich, Matthias, Betz, Matthias J., Burkard, Thilo, Cavelti-Weder, Claudia, Seelig, Eleonora, Meienberg, Fabian, Kratschmar, Denise V., Beuschlein, Felix, Reincke, Martin, , Hall, Michael N., Donath, Marc Y., & Swierczynska, Marta M. (2019). Treatment of Primary Aldosteronism with mTORC1 Inhibitors. The Journal of Clinical Endocrinology and Metabolism, 104(10), 4703–4714. https://doi.org/10.1210/jc.2019-00563
Trinh, Beckey, Hepprich, Matthias, Betz, Matthias J., Burkard, Thilo, Cavelti-Weder, Claudia, Seelig, Eleonora, Meienberg, Fabian, Kratschmar, Denise V., Beuschlein, Felix, Reincke, Martin, , Hall, Michael N., Donath, Marc Y., & Swierczynska, Marta M. (2019). Treatment of Primary Aldosteronism with mTORC1 Inhibitors. The Journal of Clinical Endocrinology and Metabolism, 104(10), 4703–4714. https://doi.org/10.1210/jc.2019-00563
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Emmerich, Juliette, van Koppen, Chris J., Burkhart, Jens L., Engeli, Roger T., Hu, Qingzhong, , & Hartmann, Rolf W. (2018). Accelerated skin wound healing by selective 11β²-Hydroxylase (CYP11B1) inhibitors. European Journal of Medicinal Chemistry, 143, 591–597. https://doi.org/10.1016/j.ejmech.2017.11.018
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Engeli, Roger T., Fürstenberger, Cornelia, Kratschmar, Denise V., & . (2018). Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis. Heliyon, 4(2), e00527. https://doi.org/10.1016/j.heliyon.2018.e00527
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Lister, Adam, Bourgeois, Soline, Imenez Silva, Pedro H., Rubio-Aliaga, Isabel, Marbet, Philippe, Walsh, Joanne, Shelton, Luke M., Keller, Bettina, Verrey, Francois, Devuyst, Olivier, Giesbertz, Pieter, Daniel, Hannelore, Goldring, Christopher E., Copple, Ian M., Wagner, Carsten A., & . (2018). NRF2 regulates the glutamine transporter Slc38a3 (SNAT3) in kidney in response to metabolic acidosis. Scientific reports, 8(1), 5629. https://doi.org/10.1038/s41598-018-24000-2
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Marbet, Philippe, Klusonova, Petra, Birk, Julia, Kratschmar, Denise V., & . (2018). Absence of hexose-6-phosphate dehydrogenase results in reduced overall glucose consumption but does not prevent 11β-hydroxysteroid dehydrogenase-1-dependent glucocorticoid activation. The FEBS journal, 285(21), 3993–4004. https://doi.org/10.1111/febs.14642
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Aghagolzadeh, Parisa, Radpour, Ramin, Bachtler, Matthias, van Goor, Harry, Smith, Edward R., Lister, Adam, , Feelisch, Martin, & Pasch, Andreas. (2017). Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation. Atherosclerosis, 265, 78–86. https://doi.org/10.1016/j.atherosclerosis.2017.08.012
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Alesutan, Ioana, Voelkl, Jakob, Feger, Martina, Kratschmar, Denise V., Castor, Tatsiana, Mia, Sobuj, Sacherer, Michael, Viereck, Robert, Borst, Oliver, Leibrock, Christina, Gawaz, Meinrad, Kuro-O, Makoto, Pilz, Stefan, Tomaschitz, Andreas, , Pieske, Burkert, Wagner, Carsten A., & Lang, Florian. (2017). Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells. Scientific Reports, 7(1), 2059. https://doi.org/10.1038/s41598-017-01882-2
Alesutan, Ioana, Voelkl, Jakob, Feger, Martina, Kratschmar, Denise V., Castor, Tatsiana, Mia, Sobuj, Sacherer, Michael, Viereck, Robert, Borst, Oliver, Leibrock, Christina, Gawaz, Meinrad, Kuro-O, Makoto, Pilz, Stefan, Tomaschitz, Andreas, , Pieske, Burkert, Wagner, Carsten A., & Lang, Florian. (2017). Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells. Scientific Reports, 7(1), 2059. https://doi.org/10.1038/s41598-017-01882-2
Araya, Selene, Kratschmar, Denise V., Tsachaki, Maria, Stücheli, Simon, Beck, Katharina R., & . (2017). DHRS7 (SDR34C1) - A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone? Journal of Steroid Biochemistry and Molecular Biology, 171, 288–295. https://doi.org/10.1016/j.jsbmb.2017.04.013
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Beck, Katharina R., Bächler, Murielle, Vuorinen, Anna, Wagner, Sandra, Akram, Muhammad, Griesser, Ulrich, Temml, Veronika, Klusonova, Petra, Yamaguchi, Hideaki, Schuster, Daniela, & . (2017). Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole. Biochemical Pharmacology, 130, 93–103. https://doi.org/10.1016/j.bcp.2017.01.010
Beck, Katharina R., Bächler, Murielle, Vuorinen, Anna, Wagner, Sandra, Akram, Muhammad, Griesser, Ulrich, Temml, Veronika, Klusonova, Petra, Yamaguchi, Hideaki, Schuster, Daniela, & . (2017). Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole. Biochemical Pharmacology, 130, 93–103. https://doi.org/10.1016/j.bcp.2017.01.010
Beck, Katharina R., Kaserer, Teresa, Schuster, Daniela, & . (2017). Virtual screening applications in short-chain dehydrogenase/reductase research. Journal of Steroid Biochemistry and Molecular Biology, 171, 157–177. https://doi.org/10.1016/j.jsbmb.2017.03.008
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Ben Rhouma, Bochra, Kallabi, Fakhri, Mahfoudh, Nadia, Ben Mahmoud, Afif, Engeli, Roger T., Kamoun, Hassen, Keskes, Leila, , & Belguith, Neila. (2017). Novel cases of Tunisian patients with mutations in the gene encoding 17β-hydroxysteroid dehydrogenase type 3 and a founder effect. Journal of Steroid Biochemistry and Molecular Biology, 165(Pt A), 86–94. https://doi.org/10.1016/j.jsbmb.2016.03.007
Ben Rhouma, Bochra, Kallabi, Fakhri, Mahfoudh, Nadia, Ben Mahmoud, Afif, Engeli, Roger T., Kamoun, Hassen, Keskes, Leila, , & Belguith, Neila. (2017). Novel cases of Tunisian patients with mutations in the gene encoding 17β-hydroxysteroid dehydrogenase type 3 and a founder effect. Journal of Steroid Biochemistry and Molecular Biology, 165(Pt A), 86–94. https://doi.org/10.1016/j.jsbmb.2016.03.007
Bonifacio, Annalisa, Sanvee, Gerda M., Brecht, Karin, Kratschmar, Denise V., , Bouitbir, Jamal, & Krähenbühl, Stephan. (2017). IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91(5), 2223–2234. https://doi.org/10.1007/s00204-016-1871-z
Bonifacio, Annalisa, Sanvee, Gerda M., Brecht, Karin, Kratschmar, Denise V., , Bouitbir, Jamal, & Krähenbühl, Stephan. (2017). IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91(5), 2223–2234. https://doi.org/10.1007/s00204-016-1871-z
Boudon, Stéphanie M., Vuorinen, Anna, Geotti-Bianchini, Piero, Wandeler, Eliane, Kratschmar, Denise V., Heidl, Marc, Campiche, Remo, Jackson, Eileen, & . (2017). Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UV. PLoS ONE, 12(2), e0171079. https://doi.org/10.1371/journal.pone.0171079
Boudon, Stéphanie M., Vuorinen, Anna, Geotti-Bianchini, Piero, Wandeler, Eliane, Kratschmar, Denise V., Heidl, Marc, Campiche, Remo, Jackson, Eileen, & . (2017). Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UV. PLoS ONE, 12(2), e0171079. https://doi.org/10.1371/journal.pone.0171079
Dolder, Patrick C., Strajhar, Petra, Vizeli, Patrick, Hammann, Felix, , & Liechti, Matthias E. (2017). Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects. Frontiers in Pharmacology, 8, 617. https://doi.org/10.3389/fphar.2017.00617
Dolder, Patrick C., Strajhar, Petra, Vizeli, Patrick, Hammann, Felix, , & Liechti, Matthias E. (2017). Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects. Frontiers in Pharmacology, 8, 617. https://doi.org/10.3389/fphar.2017.00617
Engeli, Roger T., Rohrer, Simona R., Vuorinen, Anna, Herdlinger, Sonja, Kaserer, Teresa, Leugger, Susanne, Schuster, Daniela, & . (2017). Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases. International Journal of Molecular Sciences, 18(9), 1–13. https://doi.org/10.3390/ijms18092007
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Engeli, Roger T., Tsachaki, Maria, Hassan, Heba A., Sager, Christoph P., Essawi, Mona L., Gad, Yehia Z., Kamel, Alaa K., Mazen, Inas, & . (2017). Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients. The Journal of Sexual Medicine, 14(9), 1165–1174. https://doi.org/10.1016/j.jsxm.2017.07.006
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Jiménez-Canino, Rubén, Lorenzo-Díaz, Fabián, , Bailey, Matthew A., Livingstone, Dawn E. W., Jaisser, Frederic, Farman, Nicolette, & Alvarez de la Rosa, Diego. (2017). 11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation. Endocrinology, 158(11), 4047–4063. https://doi.org/10.1210/en.2017-00440
Jiménez-Canino, Rubén, Lorenzo-Díaz, Fabián, , Bailey, Matthew A., Livingstone, Dawn E. W., Jaisser, Frederic, Farman, Nicolette, & Alvarez de la Rosa, Diego. (2017). 11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation. Endocrinology, 158(11), 4047–4063. https://doi.org/10.1210/en.2017-00440
Knöpfel, Thomas, Pastor-Arroyo, Eva M., Schnitzbauer, Udo, Kratschmar, Denise V., , Pellegrini, Giovanni, Hernando, Nati, & Wagner, Carsten A. (2017). The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction. Scientific Reports, 7(1), 11018. https://doi.org/10.1038/s41598-017-10390-2
Knöpfel, Thomas, Pastor-Arroyo, Eva M., Schnitzbauer, Udo, Kratschmar, Denise V., , Pellegrini, Giovanni, Hernando, Nati, & Wagner, Carsten A. (2017). The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction. Scientific Reports, 7(1), 11018. https://doi.org/10.1038/s41598-017-10390-2
Legeza, Balázs, Marcolongo, Paola, Gamberucci, Alessandra, Varga, Viola, Bánhegyi, Gábor, Benedetti, Angiolo, & . (2017). Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome. Nutrients, 9(5), E426. https://doi.org/10.3390/nu9050426
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Morgan, Ruth A., Beck, Katharina R., Nixon, Mark, Homer, Natalie Z. M., Crawford, Andrew A., Melchers, Diana, Houtman, René, Meijer, Onno C., Stomby, Andreas, Anderson, Anna J., Upreti, Rita, Stimson, Roland H., Olsson, Tommy, Michoel, Tom, Cohain, Ariella, Ruusalepp, Arno, Schadt, Eric E., Björkegren, Johan L. M., Andrew, Ruth, et al. (2017). Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity. Scientific Reports, 7(1), 10633. https://doi.org/10.1038/s41598-017-10410-1
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