Prof. Dr. Konrad Tiefenbacher

Syntrivanis, Leonidas‐Dimitrios, & Tiefenbacher, Konrad. (2024). Reaktivität in Molekularen Gefäßen: Beschleunigungsmodi und Arten der Erzielbaren Selektivität [Journal-article]. Angewandte Chemie, Online ahead of print. https://doi.org/10.1002/ange.202412622

Syntrivanis, Leonidas‐Dimitrios, & Tiefenbacher, Konrad. (2024). Reactivity Inside Molecular Flasks: Acceleration Modes and Types of Selectivity Obtainable [Journal-article]. Angewandte Chemie International Edition, Online ahead of print. https://doi.org/10.1002/anie.202412622

Persiani, Giacomo, Sokolova, Daria, Ivanov, Roman, Merget, Severin, Maintok, Tobias, Häussinger, Daniel, & Tiefenbacher, Konrad. (2024). Catalyzing the Enantioselective Tail‐to‐Head Terpene Cyclization Inside Optically Active Hexameric Resorcin[4]arene Capsules: A Surprising Odd‐Even Effect of the Catalyst [Journal-article]. European Journal of Organic Chemistry, Online ahead of print. https://doi.org/10.1002/ejoc.202400923

Lu, Yiheng, Knezevic, Melina, Prescimone, Alessandro, Goldfuss, Bernd, & Tiefenbacher, Konrad. (2024). Site-Selective C(sp3)–H Oxidation of Aliphatic Substrates Devoid of Functional Groups [Posted-content]. In Chemrxiv. Cambridge University Press. https://doi.org/10.26434/chemrxiv-2024-5gv6d

Strassberger, Alexander Felix, Zengaffinen, Michael David, Puigcerver, Julio, Trapp, Nils, & Tiefenbacher, Konrad. (2024). Quinoacridane[4]arenes─Very Large Conformationally Restricted Macrocycles [Journal-article]. Organic Letters, 26(31), 6720–6724. https://doi.org/10.1021/acs.orglett.4c02406

Li, T.-R., Das, C., Cornu, I., Prescimone, A., Piccini, G., & Tiefenbacher, K. (2024). Window[1]resorcin[3]arenes: A Novel Macrocycle Able to Self-Assemble to a Catalytically Active Hexameric Cage. JACS Au, 4(5), 1901–1910. https://doi.org/10.1021/jacsau.4c00097

Muthwill, Moritz S., Bina, Maryame, Paracini, Nicolò, Coats, John Peter, Merget, Severin, Yorulmaz Avsar, Saziye, Messmer, Daniel, Tiefenbacher, Konrad, & Palivan, Cornelia G. (2024). Planar Polymer Membranes Accommodate Functional Self-Assembly of Inserted Resorcinarene Nanocapsules. ACS Applied Materials and Interfaces, 16(10), 13291–13304. https://doi.org/10.1021/acsami.3c18687

Némethová, Ivana, Schmid, Dario, & Tiefenbacher, Konrad. (2023). Supramolekulare Kapselkatalyse ermöglicht die Erforschung des von der Natur unerschlossenen chemischen Raums der Terpenoide [Journal-article]. Angewandte Chemie, 135(14). https://doi.org/10.1002/ange.202218625

Cornu, Ivan, Syntrivanis, Leonidas-Dimitrios, & Tiefenbacher, Konrad. (2023). Biomimetic tail-to-head terpene cyclizations using the resorcin[4]arene capsule catalyst. Nature Protocols, null. https://doi.org/10.1038/s41596-023-00919-3

Némethová, Ivana, Schmid, Dario, & Tiefenbacher, Konrad. (2023). Supramolecular Capsule Catalysis Enables the Exploration of Terpenoid Chemical Space Untapped by Nature. Angewandte Chemie - International Edition, 62(14). https://doi.org/10.1002/anie.202218625

Schmid, Dario, Li, Tian-Ren, Goldfuss, Bernd, & Tiefenbacher, Konrad. (2023). Exploring the Glycosylation Reaction Inside the Resorcin[4]arene Capsule. Journal of Organic Chemistry, 88, 14515–14526. https://doi.org/10.1021/acs.joc.3c01547

Zenka, Mattias, Preinl, Joachim, Pertermann, Eric, Lützen, Arne, & Tiefenbacher, Konrad. (2023). A Water- and Base-Stable Iminopyridine-Based Cage That Can Bind Larger Organic Anions. European Journal of Inorganic Chemistry, 26. https://doi.org/10.1002/ejic.202300110

Pfeuffer‐Rooschüz, Jonathan, Heim, Salome, Prescimone, Alessandro, & Tiefenbacher, Konrad. (2022). Megalo‐Kavitanden: Synthese von Acridan[4]arenen und Bildung großer, tiefer Kavitanden für die selektive C 70 ‐Aufnahme [Journal-article]. Angewandte Chemie, 134(42). https://doi.org/10.1002/ange.202209885

Sokolova, Daria, Piccini, GiovanniMaria, & Tiefenbacher, Konrad. (2022). Enantioselektive Tail‐to‐Head‐Terpencyclisierungen durch optisch aktive hexamere Resorcin[4]aren‐Kapselderivate [Journal-article]. Angewandte Chemie, 134(25). https://doi.org/10.1002/ange.202203384

Chen, Hao, Li, Tian-Ren, Sakai, Naomi, Besnard, Celine, Guénée, Laure, Pupier, Marion, Viger-Gravel, Jasmine, Tiefenbacher, Konrad, & Matile, Stefan. (2022). Decoded fingerprints of hyperresponsive, expanding product space: polyether cascade cyclizations as tools to elucidate supramolecular catalysis. Chemical Science, 13(35), 10273–10280. https://doi.org/10.1039/d2sc03991e

Huck, Fabian, Catti, Lorenzo, Reber, Gian Lino, & Tiefenbacher, Konrad. (2022). Expanding the Protecting Group Scope for the Carbonyl Olefin Metathesis Approach to 2,5-Dihydropyrroles. Journal of Organic Chemistry, 87(1), 419–428. https://doi.org/10.1021/acs.joc.1c02447

Knezevic, Melina, & Tiefenbacher, Konrad. (2022). Tweezer-Based C-H Oxidation Catalysts Overriding the Intrinsic Reactivity of Aliphatic Ammonium Substrates. Chemistry - A European Journal, 29(13), e202203480. https://doi.org/10.1002/chem.202203480

Li, Tian-Ren, Huck, Fabian, Piccini, GiovanniMaria, & Tiefenbacher, Konrad. (2022). Mimicry of the proton wire mechanism of enzymes inside a supramolecular capsule enables beta-selective O-glycosylations. Nature Chemistry, 14(9), 985–994. https://doi.org/10.1038/s41557-022-00981-6

Li, Tian-Ren, Huck, Fabian, Piccini, GiovanniMaria, & Tiefenbacher, Konrad. (2022). Publisher Correction: Mimicry of the proton wire mechanism of enzymes inside a supramolecular capsule enables β-selective O-glycosylations (Nature Chemistry, (2022), 14, 9, (985-994), 10.1038/s41557-022-00981-6). Nature Chemistry, 14, 1086. https://doi.org/10.1038/s41557-022-01040-w

Li, Tian-Ren, Piccini, GiovanniMaria, & Tiefenbacher, Konrad. (2022). Supramolecular Capsule-Catalyzed Highly β-Selective Furanosylation Independent of the S<inf>N</inf>1/S<inf>N</inf>2 Reaction Pathway. Journal of the American Chemical Society, null. https://doi.org/10.1021/jacs.2c13641

Pfeuffer-Rooschüz, Jonathan, Heim, Salome, Prescimone, Alessandro, & Tiefenbacher, Konrad. (2022). Megalo-Cavitands: Synthesis of Acridane[4]arenes and Formation of Large, Deep Cavitands for Selective C70 Uptake. Angewandte Chemie International Edition, 61(42), e202209885. https://doi.org/10.1002/anie.202209885

Sokolova, Daria, Piccini, GiovanniMaria, & Tiefenbacher, Konrad. (2022). Enantioselective Tail-to-Head Terpene Cyclizations by Optically Active Hexameric Resorcin[4]arene Capsule Derivatives. Angewandte Chemie International Edition, 61(25), e202203384. https://doi.org/10.1002/anie.202203384

Li, Tian-Ren, Huck, Fabian, Piccini, GiovanniMaria, & Tiefenbacher, Konrad. (2021). Hydrogen Bond Synchronized Dual Activation Enables the Unified β-Selective O-Glycosylation Inside a Molecular Capsule [Posted-content]. In Chemrixv. Cambridge University Press. https://doi.org/10.26434/chemrxiv.14199443.v1

Hao, Xiaoyu, Li, Tian-Ren, Chen, Hao, Gini, Andrea, Zhang, Xiang, Rosset, Stéphane, Mazet, Clément, Tiefenbacher, Konrad, & Matile, Stefan. (2021). Bioinspired Ether Cyclizations within a π-Basic Capsule Compared to Autocatalysis on π-Acidic Surfaces and Pnictogen-Bonding Catalysts. Chemistry - A European Journal, 27(47), 12215–12223. https://doi.org/10.1002/chem.202101548

Heilmann, Michael, Knezevic, Melina, Piccini, GiovanniMaria, & Tiefenbacher, Konrad. (2021). Understanding the binding properties of phosphorylated glycoluril-derived molecular tweezers and selective nanomolar binding of natural polyamines in aqueous solution. Organic and Biomolecular Chemistry, 19(16), 3628–3633. https://doi.org/10.1039/d1ob00379h

Merget, Severin, Catti, Lorenzo, Zev, Shani, Major, Dan T., Trapp, Nils, & Tiefenbacher, Konrad. (2021). Concentration-Dependent Self-Assembly of an Unusually Large Hexameric Hydrogen-Bonded Molecular Cage. Chemistry - A European Journal, 27(13), 4447–4453. https://doi.org/10.1002/chem.202005046

Nemat, Suren J., Van Den Eynden, Dietger, Deblock, Loren, Heilmann, Michael, Köster, Jesper M., Parvizian, Mahsa, Tiefenbacher, Konrad, & De Roo, Jonathan. (2021). Resorcin[4]arene-based multidentate phosphate ligands with superior binding affinity for nanocrystal surfaces. Chemical Communications, 57, 4694–4697. https://doi.org/10.1039/d1cc00223f

Nemat, Suren, & Tiefenbacher, Konrad. (2021). Thioderivatives of Resorcin[4]arene and Pyrogallol[4]arene: Are Thiols Tolerated in the Self-Assembly Process? Organic Letters, 23(17), 6861–6865. https://doi.org/10.1021/acs.orglett.1c02426

Pfeuffer-Rooschüz, Jonathan, Schmid, Lucius, Prescimone, Alessandro, & Tiefenbacher, Konrad. (2021). Xanthene[n]arenes: Exceptionally Large, Bowl-Shaped Macrocyclic Building Blocks Suitable for Self-Assembly. JACS Au, 1(11), 1885–1891. https://doi.org/10.1021/jacsau.1c00343

Sokolova, Daria, & Tiefenbacher, Konrad. (2021). Optimized iminium-catalysed 1,4-reductions inside the resorcinarene capsule: achieving &gt;90% ee with proline as catalyst. RSC Advances, 11(40), 24607–24612. https://doi.org/10.1039/d1ra04333a

Syntrivanis, Leonidas-Dimitrios, & Tiefenbacher, Konrad. (2021). Catalysis Inside the Hexameric Resorcinarene Capsule: Toward Addressing Current Challenges in Synthetic Organic Chemistry: Vol. null (pp. 321–334). wiley. https://doi.org/10.1002/9783527832033.ch22

Knezevic, Melina, Heilmann, Michael, Piccini, Giovanni Maria, & Tiefenbacher, Konrad. (2020). Überwindung der intrinsischen Reaktivität bei aliphatischer C‐H‐Oxidation: Bevorzugte C3/C4‐Oxidation von aliphatischen Ammoniumsubstraten [Journal-article]. Angewandte Chemie, 132(30), 12486–12490. https://doi.org/10.1002/ange.202004242

Bissegger, Fabian R., Neuburger, Markus., & Tiefenbacher, Konrad. (2020). Scope of the direct trimerisation to C3-symmetric cyclotribenzylene derivatives. Supramolecular Chemistry, 32(5), 320–324. https://doi.org/10.1080/10610278.2020.1725514

Knezevic, Melina, Heilmann, Michael, Piccini, GiovanniMaria, & Tiefenbacher, Konrad. (2020). Overriding Intrinsic Reactivity in Aliphatic C-H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrate. Angewandte Chemie International Edition, 59(30), 12387–12391. https://doi.org/10.1002/anie.202004242

Merget, Severin, Catti, Lorenzo, Piccini, Giovanni-Maria, & Tiefenbacher, Konrad. (2020). Requirements for Terpene Cyclizations inside the Supramolecular Resorcinarene Capsule: Bound Water and its Protonation Determine the Catalytic Activit. Journal of the American Chemical Society, 142(9), 4400–4410. https://doi.org/10.1021/jacs.9b13239

Nemat, Suren, Jedrzejewska, H., Prescimone, Alessandro, Szumna, A., & Tiefenbacher, Konrad. (2020). Catechol[4]arene: The Missing Chiral Member of the Calix[4]arene Family. Organic Letters, 22(14), 5506–5510. https://doi.org/10.1021/acs.orglett.0c01864

Némethová, Ivana, Syntrivanis, Leonidas-Dimitrios, & Tiefenbacher, Konrad. (2020). Molecular Capsule Catalysis: Ready to Address Current Challenges in Synthetic Organic Chemistry? Chimia, 74(7), 561–568. https://doi.org/10.2533/chimia.2020.561

Syntrivanis, Leonidas-Dimitrios, Némethová, Ivana, Schmid, Dario, Levi, S., Prescimone, Alessandro, Bissegger, Fabian, Mayor, D. -T., & Tiefenbacher, Konrad. (2020). Four-Step Access to the Sesquiterpene Natural Product Presilphiperfolan-1β-ol and Unnatural Derivatives via Supramolecular Catalysis. Journal of the American Chemical Society, 142(12), 5894–5900. https://doi.org/10.1021/jacs.0c01464

Syntrivanis, Leonidas-Dimitrios, Levi, Shani, Prescimone, Alessandro, Major, Dan Thomas, & Tiefenbacher, Konrad. (2019). Four-Step Access to the Sesquiterpene Natural Product Presilphiperfolan-1β-ol and Unnatural Derivatives via Supramolecular Catalysis [Posted-content]. In Chemrxiv. Cambridge University Press. https://doi.org/10.26434/chemrxiv.9891341.v1

Heilmann, Michael, & Tiefenbacher, Konrad. (2019). A Modular Phosphorylated Glycoluril‐Derived Molecular Tweezer for Potent Binding of Aliphatic Diamines. Chemistry - A European Journal, 25(56), 12900–12904. https://doi.org/10.1002/chem.201902556

Köster, Jesper, Häussinger, Daniel, & Tiefenbacher, Konrad K. (2019). Activation of primary and secondary benzylic and tertiary alkyl (sp3)C-F bonds inside a self-assembled molecular container. Frontiers in Chemistry, 6, 639. https://doi.org/10.3389/fchem.2018.00639

Pahima, Efrat, Zhang, Qi, Tiefenbacher, Konrad K., & Major, Dan T. (2019). Discovering Monoterpene Catalysis Inside Nanocapsules with Multiscale Modeling and Experiments. Journal of the American Chemical Society, 141(15), 6234–6246. https://doi.org/10.1021/jacs.8b13411

Zhang, Qi, Catti, Lorenzo, Syntrivanis, Leonidas-Dimitrios, & Tiefenbacher, Konrad. (2019). En route to terpene natural products utilizing supramolecular cyclase mimetics. Natural Product Reports, Epub. https://doi.org/10.1039/c9np00003h

Zhang, Qi, & Tiefenbacher, Konrad. (2019). Sesquiterpene Cyclizations inside the Hexameric Resorcinarene Capsule: Total Synthesis of δ‐Selinene and Mechanistic Studies. Angewandte Chemie International Edition, 58(36), 12688–12695. https://doi.org/10.1002/anie.201906753

Catti, Lorenzo, & Tiefenbacher, Konrad. (2018). Brønsted‐Säure‐katalysierte Carbonyl‐Olefin‐Metathese in einer selbstorganisierten supramolekularen Wirtstruktur [Journal-article]. Angewandte Chemie, 130(44), 14797–14800. https://doi.org/10.1002/ange.201712141

Catti, Lorenzo, & Tiefenbacher, Konrad. (2018). Brønsted Acid-Catalyzed Carbonyl-Olefin Metathesis inside a Self-Assembled Supromolecular Host. Angewandte Chemie International Edition, 57, 14589–14592. https://doi.org/10.1002/anie.201712141

Köster, J., & Tiefenbacher, K. (2018). Elucidating the Importance of Hydrochloric Acid as a Cocatalyst for Resorcinarene-Capsule-Catalyzed reactions. ChemCatChem, 10, 2941. https://doi.org/10.1002/cctc.201800326

Thamm, Irene, Tiefenbacher, Konrad K., & Rychlik, Michael. (2018). Quantification of a-Thujone and its Metabolites in Human Urine after Consumption of a Sage Infusion Using Stable Isotope Dilution Assays. Toxins, 10(12), 1–10. https://doi.org/10.3390/toxins10120511

Zhang, Qi, Catti, Lorenzo, & Tiefenbacher, Konrad. (2018). Catalysis inside the Hexameric Resorcinarene Capsule. Accounts of Chemical Research, 51(9), 2107–2114. https://doi.org/10.1021/acs.accounts.8b00320

Zhang, Qi, Rinkel, Jan, Goldfuss, Bernd, Dickschat, Jeroen S., & Tiefenbacher, Konrad K. (2018). Sesquiterpene cyclizations catalysed inside the resorcinarene capsule and application in the short synthesis of isolongifolene and isolongifolenone. Nature Catalysis, 1(8), 609–615. https://doi.org/10.1038/s41929-018-0115-4

Bräuer, Thomas M., Zhang, Qi, & Tiefenbacher, Konrad. (2017). Iminium Catalysis inside a Self-Assembled Supramolecular Capsule: Scope and Mechanistic Studies. Journal of the American Chemical Society, 139(48), 17500–17507. https://doi.org/10.1021/jacs.7b08976

Catti, Lorenzo, Pöthig, Alexander, & Tiefenbacher, Konrad. (2017). Host-Catalyzed Cyclodehydration-Rearrangement Cascade Reaction of Unsaturated Tertiary Alcohols. Advanced Synthesis and Catalysis, 359(8), 1331–1338. https://doi.org/10.1002/adsc.201601363

Lou, Yu, Steib, Matthias, Zhang, Qi, Tiefenbacher, Konrad, Horváth, Anita, Jentys, Andreas, Liu, Yue, & Lercher, Johannes A. (2017). Design of stable Ni/ZrO2 catalysts for dry reforming of methane. Journal of Catalysis, 356, 147–156. https://doi.org/10.1016/j.jcat.2017.10.009

Pollok, Corina H., Zhang, Qi, Tiefenbacher, Konrad, & Merten, Christian. (2017). Chirality induction from a chiral guest to the hydrogen bonding network of its hexameric resorcinarene host capsule. ChemPhysChem, 18(15), 1987–1991. https://doi.org/10.1002/cphc.201700610

Richers, Johannes, Pöthig, Alexander, Herdtweck, Eberhardt, Sippel, Claudia, Hausch, Felix, & Tiefenbacher, Konrad. (2017). Synthesis and Neurotrophic Activity Studies of Illicium Sesquiterpene Natural Product Analogues. Chemistry - A European Journal, 23(13), 3178–3183. https://doi.org/10.1002/chem.201605362

Richers, Johannes, Pöthig, Alexander, Herdtweck, Eberhardt, Sippel, Claudia, Hausch, Felix, & Tiefenbacher, Konrad. (2017). Synthesis and Neurotrophic Activity Studies of Illicium Sesquiterpene Natural Product Analogues. Chemistry - A European Journal, 23(13), 3178–3183. https://doi.org/10.1002/chem.201605362

Zhang, Qi, Catti, Lorenzo, Kaila, Ville R. I., & Tiefenbacher, Konrad. (2017). To catalyze or not to catalyze: elucidation of the subtle differences between the hexameric capsules of pyrogallolarene and resorcinarene. Chemical Science, 8(2), 1653–1657. https://doi.org/10.1039/c6sc04565k

Zhang, Qi, Catti, Lorenzo, Pleiss, Jürgen, & Tiefenbacher, Konrad. (2017). Terpene Cyclizations inside a Supramolecular Catalyst: Leaving Group-Controlled Product Selectivity and Mechanistic Studies. Journal of the American Chemical Society, 139(33), 11482–11492. https://doi.org/10.1021/jacs.7b04480

Bräuer, Thomas M., Zhang, Qi, & Tiefenbacher, Konrad. (2016). Iminiumkatalyse in einer selbstorganisierten supramolekularen Kapsel: Modulation des Enantiomerenüberschusses [Journal-article]. Angewandte Chemie, 128(27), 7829–7832. https://doi.org/10.1002/ange.201602382

Braeuer, Thomas M., Zhang, Qi, & Tiefenbacher, Konrad. (2016). Iminium Catalysis inside a Self-Assembled Supramolecular Capsule: Modulation of Enantiomeric Excess. Angewandte Chemie International Edition, 55(27), 7698–7701. https://doi.org/10.1002/anie.201602382

Catti, Lorenzo, Bräuer, Thomas M., Zhang, Qi, & Tiefenbacher, Konrad. (2016). Exploring Catalysis inside Self-assembled Supramolecular Containers. Chimia, 70(11), 810–814. https://doi.org/10.2533/chimia.2016.810

Catti, Lorenzo, Zhang, Qi, & Tiefenbacher, Konrad. (2016). Advantages of Catalysis in Self-Assembled Molecular Capsules. Chemistry - A European Journal, 22(27), 9060–9066. https://doi.org/10.1002/chem.201600726

Catti, Lorenzo, Zhang, Qi, & Tiefenbacher, Konrad. (2016). Self-Assembled Supramolecular Structures as Catalysts for Reactions Involving Cationic Transition States [Review of Self-Assembled Supramolecular Structures as Catalysts for Reactions Involving Cationic Transition States]. Synthesis, 48, Article 3. https://doi.org/10.1055/s-0035-1560362

Richers, Johannes, Heilmann, Michael, Drees, Markus, & Tiefenbacher, Konrad. (2016). Synthesis of Lactones via C−H Functionalization of Nonactivated C(sp ³ )−H Bonds. Organic Letters, 18(24), 6472–6475. https://doi.org/10.1021/acs.orglett.6b03371

Thamm, Irene, Richers, Johannes, Rychlik, Michael, & Tiefenbacher, Konrad. (2016). A six-step total synthesis of α-thujone and d6-α-thujone, enabling facile access to isotopically labelled metabolites. Chemical Communications, 52(78), 11701–11703. https://doi.org/10.1039/c6cc05376a