Prof. Dr. Joachim Seelig

Seelig, Joachim, & Seelig, Anna. (2023). Protein Unfolding-Thermodynamic Perspectives and Unfolding Models. International journal of molecular sciences, 24(6), 5457. https://doi.org/10.3390/ijms24065457

Seelig, Joachim, & Seelig, Anna. (2023). Protein Stability─Analysis of Heat and Cold Denaturation without and with Unfolding Models. Journal of Physical Chemistry B, 127(15), 3352–3363. https://doi.org/10.1021/acs.jpcb.3c00882

Seelig, Joachim, & Seelig, Anna. (2023). Chemical Protein Unfolding - A Simple Cooperative Model. Journal of Physical Chemistry B, 127(39), 8296–8304. https://doi.org/10.1021/acs.jpcb.3c03558

Seelig, Joachim, & Seelig, Anna. (2022). Protein unfolding. Thermodynamic perspectives and unfolding models. bioRxiv. https://doi.org/10.1101/2022.11.08.515403

Seelig, Joachim, & Seelig, Anna. (2021). Molecular Understanding of Calorimetric Protein Unfolding Experiments. Biophysical Reports, 2(1), 100037. https://doi.org/10.1016/j.bpr.2021.100037

Garidel, Patrick, Eiperle, Andrea, Blech, Michaela, & Seelig, Joachim. (2020). Thermal and Chemical Unfolding of a Monoclonal IgG1 Antibody: Application of the Multistate Zimm-Bragg Theory. Biophysical Journal, 118(5), 1067–1075. https://doi.org/10.1016/j.bpj.2019.12.037

Li-Blatter, Xiaochun, & Seelig, Joachim. (2019). Thermal and Chemical Unfolding of Lysozyme. Multistate Zimm-Bragg Theory Versus Two-State Model. The Journal of Physical Chemistry. B, 123(48), 10181–10191. https://doi.org/10.1021/acs.jpcb.9b08816

Eckhardt, D., Li-Blatter, X., Schönfeld, H.-J., Heerklotz, H., & Seelig, J. (2018). Cooperative unfolding of apolipoprotein A-1 induced by chemical denaturation. Biophysical Chemistry, 240, 42–49. https://doi.org/10.1016/j.bpc.2018.05.005

Seelig, Joachim. (2018). Cooperative protein unfolding. A statistical-mechanical model for the action of denaturants. Biophysical Chemistry, 233, 19–25. https://doi.org/10.1016/j.bpc.2017.12.001

Seelig, Joachim. (2018). Titration Calorimetry and Differential Scanning Calorimetry of Lipid-Protein Interactions. In Wilhelm, Emmerich; Letcher, Trevor M. (Ed.), Enthalpy and Internal Energy. Liquids, Solutions and Vapours (pp. 299–314). Royal Society of Chemistry. https://doi.org/10.1039/9781788010214

Assmus, Frauke, Ross, Alfred, Fischer, Holger, Seelig, Joachim, & Seelig, Anna. (2017). (31)P and (1)H NMR Studies of the Molecular Organization of Lipids in the Parallel Artificial Membrane Permeability Assay. Molecular Pharmaceutics, 14(1), 284–295. https://doi.org/10.1021/acs.molpharmaceut.6b00889

Schönfeld, Hans-Joachim, Roessner, Dierk, & Seelig, Joachim. (2016). Self-Association of Apo A-1 Studied with Dynamic and Static Light Scattering. Journal of Physical Chemistry B, 120(7), 1228–1235. https://doi.org/10.1021/acs.jpcb.5b12397

Seelig, Joachim, & Schönfeld, Hans-Joachim. (2016). Thermal protein unfolding by differential scanning calorimetry and circular dichroism spectroscopy Two-state model versus sequential unfolding. Quarterly Reviews of Biophysics, 49, e9. https://doi.org/10.1017/s0033583516000044

Schulthess, Therese, Schönfeld, Hans-Joachim, & Seelig, Joachim. (2015). Thermal unfolding of apolipoprotein a-1 : evaluation of methods and models. Biochemistry, 54(19), 3063–3075. https://doi.org/10.1021/acs.biochem.5b00238

Voievoda, Nataliia, Schulthess, Therese, Bechinger, Burkhard, & Seelig, Joachim. (2015). Thermodynamic and Biophysical Analysis of the Membrane-Association of a Histidine-Rich Peptide with Efficient Antimicrobial and Transfection Activities. Journal of Physical Chemistry B, 119(30), 9678–9687. https://doi.org/10.1021/acs.jpcb.5b04543

Schmidt, Annika, Belaaouaj, Azzaq, Bissinger, Rosi, Koller, Garrit, Malleret, Laurette, D’Orazio, Ciro, Facchinelli, Martino, Schulte-Hubbert, Bernhard, Molinaro, Antonio, Holst, Otto, Hammermann, Jutta, Schniederjans, Monika, Meyer, Keith C., Damkiaer, Soeren, Piacentini, Giorgio, Assael, Baroukh, Bruce, Kenneth, Häußler, Susanne, LiPuma, John J., et al. (2014). Neutrophil elastase-mediated increase in airway temperature during inflammation. Journal of Cystic Fibrosis, 13(6), 623–631. https://doi.org/10.1016/j.jcf.2014.03.004

Domingues, Tatiana M., Mattei, Bruno, Seelig, Joachim, Perez, Katia R., Miranda, Antonio, & Riske, Karin A. (2013). Interaction of the antimicrobial Peptide gomesin with model membranes : a calorimetric study. Langmuir, 29(27), 8609–8618. https://doi.org/10.1021/la401596s

Perspicace, Samantha, Rufer, Arne C., Thoma, Ralf, Müller, Francis, Hennig, Michael, Ceccarelli, Simona, Schulz-Gasch, Tanja, & Seelig, Joachim. (2013). Isothermal titration calorimetry with micelles : thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein. FEBS Open Bio, 3, 204–211. https://doi.org/10.1016/j.fob.2013.04.003

Québatte, Gabriela, Kitas, Eric, & Seelig, Joachim. (2013). riDOM, a Cell-Penetrating Peptide : Interaction with DNA and Heparan Sulfate. Journal of Physical Chemistry B, 117(37), 10807–10817. https://doi.org/10.1021/jp404979y

Québatte, Gabriela, Kitas, Eric, & Seelig, Joachim. (2013). riDOM, a cell penetrating peptide : interaction with phospholipid bilayers. BBA - Biochimica et Biophysica Acta, 1838(3), 968–977. https://doi.org/10.1016/j.bbamem.2013.10.017

Zehender, F, Ziegler, A, Schönfeld, H-J, & Seelig, J. (2012). Thermodynamics of protein self-association and unfolding : the case of apolipoprotein a-I. Biochemistry, 51(6), 1269–1280. https://doi.org/10.1021/bi2013799

Loew, C., Riske, K. A., Lamy, M. T., & Seelig, J. (2011). Thermal Phase Behavior of DMPG as revealed by 2H- and 31P- NMR. Langmuir, 27(16), 10041–10049. https://doi.org/10.1021/la201027p

Sauder, Reto, Seelig, Joachim, & Ziegler, André. (2011). Thermodynamics of lipid interactions with cell-penetrating peptides. Methods in Molecular Biology, 683, 129–155. https://doi.org/10.1007/978-1-60761-919-2_10

Ziegler, Andre, & Seelig, Joachim. (2011). Contributions of Glycosaminoglycan Binding and Clustering to the Biological Uptake of the Nonamphipathic Cell-Penetrating Peptide WR(9). Biochemistry, 50(21), 4650–4664. https://doi.org/10.1021/bi1019429

Beck, A., Li-Blatter, X., Seelig, A., & Seelig, J. (2010). On the Interaction of Ionic Detergents with Lipid Membranes : Thermodynamic Comparison of n-Alkyl-+N(CH3)3 and n-Alkyl-SO4-. Journal of Physical Chemistry B, 114(48), 15862–15871. https://doi.org/10.1021/jp107088d

Meier, Matthias, & Seelig, Joachim. (2010). Lipid and peptide dynamics in membranes upon insertion of n-alkyl-beta-D-glucopyranosides. Biophysical Journal, 98(8), 1529–1538. https://doi.org/10.1016/j.bpj.2009.12.4286

Hayley, Michael, Perspicace, Samantha, Schulthess, Therese, & Seelig, Joachim. (2009). Calcium enhances the proteolytic activity of BACE1 : an in vitro biophysical and biochemical characterization of the BACE1-calcium interaction. Biochimica et Biophysica Acta, 1788(9), 1933–1938. https://doi.org/10.1016/j.bbamem.2009.05.015

Klocek, Gabriela, Schulthess, Therese, Shai, Yechiel, & Seelig, Joachim. (2009). Thermodynamics of melittin binding to lipid bilayers. Aggregation and pore formation. Biochemistry, 48(12), 2586–2596. https://doi.org/10.1021/bi802127h

Klocek, Gabriela, & Seelig, Joachim. (2008). Melittin interaction with sulfated cell surface sugars. Biochemistry, 47(9), 2841–2849. https://doi.org/10.1021/bi702258z

Meier, M., & Seelig, J. (2008). Length dependence of the coil beta-sheet transition in a membrane environment. Journal of the American Chemical Society, 130(3), 1017–1024. https://doi.org/10.1021/ja077231r

Ziegler, André, & Seelig, Joachim. (2008). Binding and clustering of glycosaminoglycans : a common property of mono- and multivalent cell-penetrating compounds. Biophysical Journal, 94(6), 2142–2149. https://doi.org/10.1529/biophysj.107.113472

Brockhaus, M., Ganz, P., Huber, W., Bohrmann, B., Loetscher, H. -R., & Seelig, J. (2007). Thermodynamic studies on the interaction of antibodies with beta-amyloid peptide. Journal of Physical Chemistry B, 111(5), 1238–1243. https://doi.org/10.1021/jp0664059

Heerklotz, H., & Seelig, J. (2007). Leakage and lysis of lipid membranes induced by the lipopeptide surfactin. European Biophysics Journal, 36(4-5), 305–314. https://doi.org/10.1007/s00249-006-0091-5

Kohler, G., Rost, F., & Seelig, J. (2007). Simultaneous separation of intracellular and extracellular lactate NMR signals of human erythrocytes. Magnetic Resonance in Medicine, 58(2), 213–217. https://doi.org/10.1002/mrm.21309

Meier, Matthias, & Seelig, Joachim. (2007). Thermodynamics of the coil beta-sheet transition in a membrane environment. Journal of Molecular Biology, 369(1), 277–289. https://doi.org/10.1016/j.jmb.2007.02.082

Ziegler, André, & Seelig, Joachim. (2007). High affinity of the cell-penetrating peptide HIV-1 Tat-PTD for DNA. Biochemistry, 46(27), 8138–8145. https://doi.org/10.1021/bi700416h

Gonçalves, Elisabete, Kitas, Eric, & Seelig, Joachim. (2006). Structural and thermodynamic aspects of the interaction between heparan sulfate and analogues of melittin. Biochemistry, 45(9), 3086–3094. https://doi.org/10.1021/bi052221t

Honnappa, Srinivas, Jahnke, Wolfgang, Seelig, Joachim, & Steinmetz, Michel O. (2006). Control of intrinsically disordered stathmin by multisite phosphorylation. Journal of Biological Chemistry, 281(23), 16078–16083. https://doi.org/10.1074/jbc.m513524200

Meier, M, Blatter, X Li, Seelig, A, & Seelig, J. (2006). Interaction of verapamil with lipid membranes and P-glycoprotein : connecting thermodynamics and membrane structure with functional activity. Biophysical Journal, 91(8), 2943–2955. https://doi.org/10.1529/biophysj.106.089581

Gonçalves, Elisabete, Kitas, Eric, & Seelig, Joachim. (2005). Binding of oligoarginine to membrane lipids and heparan sulfate : structural and thermodynamic characterization of a cell-penetrating peptide. Biochemistry, 44(7), 2692–2702. https://doi.org/10.1021/bi048046i

Ziegler, André, Nervi, Pierluigi, Dürrenberger, Markus, & Seelig, Joachim. (2005). The cationic cell-penetrating peptide CPP(TAT) derived from the HIV-1 protein TAT is rapidly transported into living fibroblast : optical, biophysical, and metabolic evidence. Biochemistry, 44(1), 138–148. https://doi.org/10.1021/bi0491604

Anderson, Thomas G, Tan, Anmin, Ganz, Peter, & Seelig, Joachim. (2004). Calorimetric measurement of phospholipid interaction with methyl-beta-cyclodextrin. Biochemistry, 43(8), 2251–2261. https://doi.org/10.1021/bi0358869

Heerklotz, Heiko, Wieprecht, Torsten, & Seelig, Joachim. (2004). Membrane perturbation by the lipopeptide surfactin and detergents as studied by deuterium NMR. Journal of Physical Chemistry B, 108(15), 4909–4915. https://doi.org/10.1021/jp0371938

Schwarz, R., Seelig, J., & Kunnecke, B. (2004). Structural properties of perfluorinated linear alkanes : a 19F and 13C NMR study of perfluorononane. Magnetic Resonance in Chemistry, 42(6), 512–517. https://doi.org/10.1002/mrc.1380

Seelig, J. (2004). Thermodynamics of lipid-peptide interactions. Biochimica et Biophysica Acta, 1666(1-2), 40–50. https://doi.org/10.1016/j.bbamem.2004.08.004

Ziegler, André, & Seelig, Joachim. (2004). Interaction of the protein transduction domain of HIV-1 TAT with heparan sulfate : binding mechanism and thermodynamic parameters. Biophysical Journal, 86(1 Pt 1), 254–263. https://doi.org/10.1016/s0006-3495(04)74101-6

Bilecen, D., Schulte, A. -C., Kaspar, A., Kustermann, E., Seelig, J., Elverfeldt, D., & Scheffler, K. (2003). Detection of the non-steroidal anti-inflammatory drug niflumic acid in humans : a combined 19F-MRS in vivo and in vitro study. NMR in Biomedicine, 16(3), 144–151. https://doi.org/10.1002/nbm.820

Heerklotz, Heiko, Szadkowska, Halina, Anderson, Thomas, & Seelig, Joachim. (2003). The sensitivity of lipid domains to small perturbations demonstrated by the effect of Triton. Journal of Molecular Biology, 329(4), 793–799. https://doi.org/10.1016/s0022-8236(03)00504-7

Honnappa, S, Cutting, B, Jahnke, W, Seelig, J, & Steinmetz, MO. (2003). Thermodynamics of the Op18/stathmin-tubulin interaction. Journal of Biological Chemistry, 278(40), 38926–38934. https://doi.org/10.1074/jbc.m305546200

Karelson, G., Ziegler, A., Kunnecke, B., & Seelig, J. (2003). Feeding versus infusion : a novel approach to study the NAA metabolism in rat brain. NMR in Biomedicine, 16(6-7), 413–423. https://doi.org/10.1002/nbm.845

Machaidze, Gia, & Seelig, Joachim. (2003). Specific binding of cinnamycin (Ro 09-0198) to phosphatidylethanolamine : Comparison between micellar and membrane environments. Biochemistry, 42(43), 12570–12576. https://doi.org/10.1021/bi035225b

Ziegler, André, Blatter, Xiaochun Li, Seelig, Anna, & Seelig, Joachim. (2003). Protein transduction domains of HIV-1 and SIV TAT interact with charged lipid vesicles : binding mechanism and thermodynamic analysis. Biochemistry, 42(30), 9185–9194. https://doi.org/10.1021/bi0346805

Haselhorst, R, Dursteler-MacFarland, KM, Scheffler, K, Ladewig, D, Muller-Spahn, F, Stohler, R, Seelig, J, & Seifritz, E. (2002). Frontocortical N-acetylaspartate reduction associated with long-term iv heroin use. Neurology, 58(2), 305–307. https://doi.org/10.1212/wnl.58.2.305

Heerklotz, Heiko, & Seelig, Joachim. (2002). Application of pressure perturbation calorimetry to lipid bilayers. Biophysical Journal, 82(3), 1445–1452. https://doi.org/10.1016/s0006-3495(02)75498-2

Machaidze, Gia, Ziegler, André, & Seelig, Joachim. (2002). Specific binding of Ro 09-0198 (cinnamycin) to phosphatidylethanolamine : a thermodynamic analysis. Biochemistry, 41(6), 1965–1971. https://doi.org/10.1021/bi015841c

Schote, Uwe, Ganz, Peter, Fahr, Alfred, & Seelig, Joachim. (2002). Interactions of cyclosporines with lipid membranes as studied by solid-state nuclear magnetic resonance spectroscopy and high-sensitivity titration calorimetry. Journal of Pharmaceutical Sciences, 91(3), 856–867. https://doi.org/10.1002/jps.10071

Schwarz, R., Kaspar, A., Seelig, J., & Kunnecke, B. (2002). Gastrointestinal transit times in mice and humans measured with 27Al and 19F nuclear magnetic resonance. Magnetic Resonance in Medicine, 48(2), 255–261. https://doi.org/10.1002/mrm.10207

Tan, Anmin, Ziegler, André, Steinbauer, Bernhard, & Seelig, Joachim. (2002). Thermodynamics of sodium dodecyl sulfate partitioning into lipid membranes. Biophysical Journal, 83(3), 1547–1556. https://doi.org/10.1016/s0006-3495(02)73924-6

Wieprecht, T., Beyermann, M., & Seelig, J. (2002). Thermodynamics of the coil-alpha-helix transition of amphipathic peptides in a membrane environment : the role of vesicle curvature. Biophysical Chemistry, 96(2-3), 191–201. https://doi.org/10.1016/s0301-4622(02)00025-x

Ziegler, A., Zaugg, C. E., Buser, P. T., Seelig, J., & Kunnecke, B. (2002). Non-invasive measurements of myocardial carbon metabolism using in vivo 13C NMR spectroscopy. NMR in Biomedicine, 15(3), 222–234. https://doi.org/10.1002/nbm.764

Seelig, A., & Seelig, J. (2002). Membrane structure. In R.A. Meyers, (Ed.), Encyclopedia of physical science and technology: Vol. Vol. 9 (p. S. 355–367). Academic Press.

Wieprecht, T., & Seelig, J. (2002). Isothermal titration calorimetry for studying interactions between peptides and lipid membranes. In S.A. Simon,; T.J. McIntosh, (Ed.), Peptide-lipid interactions (p. S. 31–56). Academic Press. https://doi.org/10.1016/s1063-5823(02)52004-4

Fahr, A., & Seelig, J. (2001). Liposomal formulations of Cyclosporin A : a biophysical approach to pharmacokinetics and pharmacodynamics. Critical Reviews in Therapeutic Drug Carrier Systems, 18(2), 141–172. https://doi.org/10.1023/a:1016220211925

Heerklotz, H, & Seelig, J. (2001). Detergent-like action of the antibiotic peptide surfactin on lipid membranes. Biophysical Journal, 81(3), 1547–1554. https://doi.org/10.1016/s0006-3495(01)75808-0

Breukink, E, Ganz, P, de Kruijff, B, & Seelig, J. (2000). Binding of Nisin Z to bilayer vesicles as determined with isothermal titration calorimetry. Biochemistry, 39(33), 10247–10254. https://doi.org/10.1021/bi000915q

Haselhorst, R., Kappos, L., Bilecen, D., Scheffler, K., Mori, D., Radu, E. W., & Seelig, J. (2000). Dynamic susceptibility contrast MR imaging of plaque development in multiple sclerosis : application of an extended blood-brain barrier leakage correction. Journal of Magnetic Resonance Imaging, 11(5), 495–505. https://doi.org/10.1002/(sici)1522-2586(200005)11:53.0.co;2-s

Heerklotz, H, & Seelig, J. (2000). Titration calorimetry of surfactant-membrane partitioning and membrane solubilization. Biochimica et Biophysica Acta, 1508(1-2), 69–85. https://doi.org/10.1016/s0304-4157(00)00009-5

Kunnecke, B., Kustermann, E., & Seelig, J. (2000). Simultaneous in vivo monitoring of hepatic glucose and glucose-6-phosphate by (13)C-NMR spectroscopy. Magnetic Resonance in Medicine, 44(4), 556–562. https://doi.org/10.1002/1522-2594(200010)44:43.0.co;2-3

Mader, I., Roser, W., Kappos, L., Hagberg, G., Seelig, J., Radue, E. W., & Steinbrich, W. (2000). Serial proton MR spectroscopy of contrast-enhancing multiple sclerosis plaques : absolute metabolic values over 2 years during a clinical pharmacological study. American Journal of Neuroradiology, 21(7), 1220–1227. http://www.ajnr.org/content/21/7/1220

Seelig, J. (2000). Correlation of membrane / water partition coefficients of detergents with the critical micelle concentration. Biophysical Journal, 78(5), 2435–2440. https://doi.org/10.1016/s0006-3495(00)76787-7

Seifritz, E, Bilecen, D, Hänggi, D, Haselhorst, R, Radü, E W, Wetzel, S, Seelig, J, & Scheffler, K. (2000). Effect of ethanol on BOLD response to acoustic stimulation : implications for neuropharmacological fMRI. Psychiatry Research, 99(1), 1–13. https://doi.org/10.1016/s0925-4927(00)00054-8

Wieprecht, T, Apostolov, O, Beyermann, M, & Seelig, J. (2000). Membrane binding and pore formation of the antibacterial peptide PGLa : thermodynamic and mechanistic aspects. Biochemistry, 39(2), 442–452. https://doi.org/10.1021/bi992146k

Wieprecht, T, Apostolov, O, Beyermann, M, & Seelig, J. (2000). Interaction of a mitochondrial presequence with lipid membranes : role of helix formation for membrane binding and perturbation. Biochemistry, 39(50), 15297–15305. https://doi.org/10.1021/bi001774v

Wieprecht, T., Apostolov, O., & Seelig, J. (2000). Binding of the antibacterial peptide magainin 2 amide to small and large unilamellar vesicles. Biophysical Chemistry, 85(2-3), 187–198. https://doi.org/10.1016/s0301-4622(00)00120-4

Fischer, H., Seelig, A., Beier, N., Raddatz, P., & Seelig, J. (1999). New drugs for the Na+/H+ exchanger : Influence of Na+ concentration and determination of inhibition constants with a microphysiometer. The Journal of Membrane Biology, 168(1), 39–45. https://doi.org/10.1007/s002329900496

Pellaud, J, Schote, U, Arvinte, T, & Seelig, J. (1999). Conformation and self-association of human recombinant transforming growth factor-beta3 in aqueous solutions. Journal of Biological Chemistry, 274(12), 7699–7704. https://doi.org/10.1074/jbc.274.12.7699

Roser, W., Bubl, R., Buergin, D., Seelig, J., Radue, E. W., & Rost, B. (1999). Metabolic changes in the brain of patients with anorexia and bulimia nervosa as detected by proton magnetic resonance spectroscopy. International Journal of Eating Disorders, 26(2), 119–136. https://doi.org/10.1002/(sici)1098-108x(199909)26:23.0.co;2-m

Schwarz, R., Schuurmans, M., Seelig, J., & Kunnecke, B. (1999). 19F-MRI of perfluorononane as a novel contrast modality for gastrointestinal imaging. Magnetic Resonance in Medicine, 41(1), 80–86. https://doi.org/10.1002/(sici)1522-2594(199901)41:13.0.co;2-6

Wieprecht, T, Apostolov, O, Beyermann, M, & Seelig, J. (1999). Thermodynamics of the alpha-helix-coil transition of amphipathic peptides in a membrane environment : implications for the peptide-membrane binding equilibrium. Journal of Molecular Biology, 294(3), 785–794. https://doi.org/10.1006/jmbi.1999.3268

Wieprecht, T, Beyermann, M, & Seelig, J. (1999). Binding of antibacterial magainin peptides to electrically neutral membranes : thermodynamics and structure. Biochemistry, 38(32), 10377–10387. https://doi.org/10.1021/bi990913+

Seelig, Joachim. (1999). Introduction into in vivo NMR spectroscopy. In Maraviglia, B. (Ed.), Magnetic resonance and brain function (Proceedings of the International School of Physics “Enrico Fermi”, Course 139) (p. S. 1–13). IOS Press.

Seelig, Joachim. (1999). In vivo 13C-, 15N-, and 19F-Magnetic resonance spectroscopy of the brain. In Maraviglia, B. (Ed.), Magnetic resonance and brain function (Proceedings of the International School of Physics “Enrico Fermi”, Course 139) (p. S. 31–43). IOS Press.

Seelig, J., & Scheffler, K. (1999). Introduction into magnetic resonance imaging. In B. Maraviglia, (Ed.), Magnetic resonance and brain function (Proceedings of the International School of Physics “Enrico Fermi”, Course 139) (p. S. 15–30). IOS Press.

Bilecen, D., Scheffler, K., Schmid, N., Tschopp, K., & Seelig, J. (1998). Tonotopic organization of the human auditory cortex as detected by BOLD-FMRI. Hearing Research, 126(1-2), 19–27. https://doi.org/10.1016/s0378-5955(98)00139-7

Haselhorst, R., Scheffler, K., Faletti, L., Kaspar, A., Prunte, C., & Seelig, J. (1998). 29Si imaging of silicone breast implants and intraocular silicone oil. Magnetic Resonance in Medicine, 40(1), 170–174. https://doi.org/10.1002/mrm.1910400123

Küstermann, E, Seelig, J, & Künnecke, B. (1998). Ascorbic acid, a vitamin, is observed by in vivo 13C nuclear magnetic resonance spectroscopy of rat liver. American Journal of Physiology. Endocrinology and Metabolism, 274(1 Pt 1), E65–71.

Scheffler, K., Bilecen, D., Schmid, N., Tschopp, K., & Seelig, J. (1998). Auditory cortical responses in hearing subjects and unilateral deaf patients as detected by functional magnetic resonance imaging. Cerebral Cortex, 8(2), 156–163. https://doi.org/10.1093/cercor/8.2.156

Schote, U, & Seelig, J. (1998). Interaction of the neuronal marker dye FM1-43 with lipid membranes : thermodynamics and lipid ordering. Biochimica et Biophysica Acta, 1415(1), 135–146. https://doi.org/10.1016/s0005-2736(98)00188-6

Wenk, M R, & Seelig, J. (1998). Magainin 2 amide interaction with lipid membranes : calorimetric detection of peptide binding and pore formation. Biochemistry, 37(11), 3909–3916. https://doi.org/10.1021/bi972615n

Wenk, M R, & Seelig, J. (1998). Proton induced vesicle fusion and the isothermal lalpha--. Biochimica et Biophysica Acta, 1372(2), 227–236. https://doi.org/10.1016/s0005-2736(98)00059-5

Hertel, C, Terzi, E, Hauser, N, Jakob-Rotne, R, Seelig, J, & Kemp, J A. (1997). Inhibition of the electrostatic interaction between beta-amyloid peptide and membranes prevents beta-amyloid-induced toxicity. Proceedings of the National Academy of Sciences of the United States of America, 94(17), 9412–9416. https://doi.org/10.1073/pnas.94.17.9412

Nebel, S, Ganz, P, & Seelig, J. (1997). Heat changes in lipid membranes under sudden osmotic stress. Biochemistry, 36(10), 2853–2859. https://doi.org/10.1021/bi961839n

Roser, W, Hagberg, G, Mader, I, Dellas, S, Seelig, J, Radue, E W, & Steinbrich, W. (1997). Assignment of glial brain tumors in humans by in vivo 1H-magnetic resonance spectroscopy and multidimensional metabolic classification. Magma, 5(3), 179–183. https://doi.org/10.1007/bf02594580

Seelig, J. (1997). Titration calorimetry of lipid-peptide interactions. Biochimica et Biophysica Acta, 1331(1), 103–116. https://doi.org/10.1016/s0304-4157(97)00002-6

Terzi, E, Hölzemann, G, & Seelig, J. (1997). Interaction of Alzheimer beta-amyloid peptide(1-40) with lipid membranes. Biochemistry, 36(48), 14845–14852. https://doi.org/10.1021/bi971843e

Wenk, Markus R., & Seelig, Joachim. (1997). Vesicle-micelle transformation of phosphatidylcholine / octyl-beta-D-glucopyranoside mixtures as detected with titration calorimetry. Journal of Physical Chemistry B, 101(26), 5224–5231. https://doi.org/10.1021/jp9707955

Wenk, M. R., Alt, T., Seelig, A., & Seelig, J. (1997). Octyl-beta-D-glucopyranoside partitioning into lipid bilayers: thermodynamics of binding and structural changes of the bilayer. Biophysical Journal, 72(4), 1719–1731. https://doi.org/10.1016/s0006-3495(97)78818-0

Wenk, M R, & Seelig, J. (1997). Interaction of octyl-beta-thioglucopyranoside with lipid membranes. Biophysical Journal, 73(5), 2565–2574. https://doi.org/10.1016/s0006-3495(97)78285-7

Fried, R, Beckmann, N, Keller, U, Ninnis, R, Stalder, G, & Seelig, J. (1996). Early glycogenolysis and late glycogenesis in human liver after intravenous administration of galactose. American Journal of Physiology. Gastrointestinal and Liver Physiology, 270(1 Pt 1), G14–9.

Kaspar, A., Bilecen, D., Scheffler, K., & Seelig, J. (1996). Aluminum-27 nuclear magnetic resonance spectroscopy and imaging of the human gastric lumen. Magnetic Resonance in Medicine, 36(2), 177–182. https://doi.org/10.1002/mrm.1910360202