Prof. Dr. med. Tobias Johannes Derfuss

Maceski, Aleksandra Maleska, Benkert, Pascal, Einsiedler, Maximilian, Schaedelin, Sabine, Oechtering, Johanna, Melie-Garcia, Lester, Cagol, Alessandro, Galbusera, Riccardo, Galli, Edoardo, Mueller, Jannis, Finkener, Sebastian, Lalive, Patrice H, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, Mathias, Amandine, Du Pasquier, Renaud, Hoepner, Robert, Chan, Andrew, et al. (2025). GFAP and NfL as predictors of disease progression and relapse activity in fingolimod-treated multiple sclerosis [Journal-article]. Brain. https://doi.org/10.1093/brain/awaf433

Einsiedler, Maximilian, Maceski, Aleksandra Maleska, Sandgren, Sofia, Oechtering, Johanna, Schaedelin, Sabine, Hofer, Lisa, Zadic, Amar, Gomez, Juan Francisco Vilchez, Melie-Garcia, Lester, Cagol, Alessandro, Galbusera, Riccardo, Finkener, Sebastian, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, Mathias, Amandine, Du Pasquier, Renaud, Hoepner, Robert, et al. (2025). Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age- and BMI-Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response. Annals of Clinical and Translational Neurology, 12, 2214–2225. https://doi.org/10.1002/acn3.70149

Sandgren, Sofia, Maceski, Aleksandra Maleska, Benkert, Pascal, Einsiedler, Maximilian, Schaedelin, Sabine, Oechtering, Johanna, Achtnichts, Lutz, Lalive, Patrice H, Müller, Stefanie, Pot, Caroline, Heslegrave, Amanda, Hunt, David, Lycke, Jan, Hoepner, Robert, Roth, Patrick, Gobbi, Claudio, Comabella, Manuel, Derfuss, Tobias, Kappos, Ludwig, et al. (2025). Biomarker discovery using NUcleic Acid-Linked Immuno-Sandwich Assay in multiple sclerosis patients experiencing progression independent of relapse activity. Multiple Sclerosis Journal, 31, 1531–1542. https://doi.org/10.1177/13524585251375780

Wiendl, Heinz, Barkhof, Frederik, Montalban, Xavier, Achiron, Anat, Derfuss, Tobias, Chan, Andrew, Hodgkinson, Suzanne, Prat, Alexandre, Leocani, Letizia, Schmierer, Klaus, Sellebjerg, Finn, Vermersch, Patrick, Jin, Hulin, Chudecka, Anita, Kloetgen, Andreas, Lin, Dongdong, Gardner, Lidia, & De Stefano, Nicola. (2025). Summary of Research: Blood Biomarker Dynamics in People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Results of the 2-Year MAGNIFY-MS Study. Neurology and Therapy, 14(5), 1743–1746. https://doi.org/10.1007/s40120-025-00782-2

Chen, Xinjie, Lu, Po-Jui, Ocampo-Pineda, Mario, Cagol, Alessandro, Schaedelin, Sabine Anna, Ruberte, Esther, Weigel, Matthias, Spagnolo, Federico, Benkert, Pascal, Lieb, Johanna Maria, Leppert, David, Yaldizli, Özgr, Oechtering, Johanna, D’Souza, Marcus, Fischer-Barnicol, Bettina, Derfuss, Tobias J., Ekerdt, Clara, Menks, Willeke M., Chan, Kwok-Shing, et al. (2025). Unraveling Microstructural and Macrostructural Brain Age Dynamics in Multiple Sclerosis. Neurology: Neuroimmunology and NeuroInflammation, 12(5). https://doi.org/10.1212/nxi.0000000000200459

Cagol, Alessandro, Schaedelin, Sabine, Ocampo-Pineda, Mario, Benkert, Pascal, Melie-Garcia, Lester, Luchetti, Ludovico, Yaldizli, Özgür, Oechtering, Johanna, D’Souza, Marcus, Fischer-Barnicol, Bettina, Müller, Stefanie, Finkener, Sebastian, Vehoff, Jochen, Disanto, Giulio, Chan, Andrew, Pot, Caroline, Zecca, Chiara, Derfuss, Tobias, Lieb, Johanna M., et al. (2025). Comparative effectiveness of teriflunomide and ocrelizumab on smoldering activity in multiple sclerosis: an observational study in the Swiss Multiple Sclerosis Cohort. Journal of Neurology, 272(8). https://doi.org/10.1007/s00415-025-13221-x

Einsiedler, Maximilian, Zecca, Chiara, Hofer, Lisa, Benkert, Pascal, Axfors, Cathrine, Bedussi, Francesca, Ceschi, Alessandro, Disanto, Giulio, Müller, Jannis, Oechtering, Johanna, Lorscheider, Johannes, Galli, Edoardo, Fischer-Barnicol, Bettina, D’Souza, Marcus, Schaedelin, Sabine Anna, Maleska Maceski, Aleksandra, Hoepner, Robert, Chan, Andrew, Granziera, Cristina, et al. (2025). Treatment Strategies and Disease Activity During Pregnancy and Postpartum. Neurology Clinical Practice, 15(4). https://doi.org/10.1212/cpj.0000000000200499

Yaldizli, Özgür, Benkert, Pascal, Achtnichts, Lutz, Bar-Or, Amit, Bohner-Lang, Viviane, Bridel, Claire, Comabella, Manuel, Findling, Oliver, Disanto, Giulio, Finkener, Sebastian, Gobbi, Claudio, Granziera, Cristina, Herwerth, Marina, Hoepner, Robert, Horakova, Dana, Kamber, Nicole, Khalil, Michael, Kunz, Philipp, Lalive, Patrice, et al. (2025). Personalized treatment decision algorithms for the clinical application of serum neurofilament light chain in multiple sclerosis: A modified Delphi Study. Multiple Sclerosis Journal, 31, 932–943. https://doi.org/10.1177/13524585251335466

Müller, Jannis, Sharmin, Sifat, Lorscheider, Johannes, Ozakbas, Serkan, Karabudak, Rana, Horakova, Dana, Weinstock-Guttman, Bianca, Shaygannejad, Vahid, Etemadifar, Masoud, Alroughani, Raed, Patti, Francesco, Eichau, Sara, Prat, Alexandre, Lugaresi, Alessandra, Tomassini, Valentina, Kermode, Allan G., Amato, Maria Pia, Turkoglu, Recai, Altintas, Ayse, et al. (2025). Standardized Definition of Progression Independent of Relapse Activity (PIRA) in Relapsing-Remitting Multiple Sclerosis. JAMA Neurology, 82(6), 614–625. https://doi.org/10.1001/jamaneurol.2025.0495

Androdias, Géraldine, Lünemann, Jan D, Maillart, Elisabeth, Amato, Maria Pia, Audoin, Bertrand, Bruijstens, Arlette L, Bsteh, Gabriel, Butzkueven, Helmut, Ciccarelli, Olga, Cobo-Calvo, Alvaro, Derfuss, Tobias, Di Pauli, Franziska, Edan, Gilles, Enzinger, Christian, Geraldes, Ruth, Granziera, Cristina, Hacohen, Yael, Hartung, Hans-Peter, Hynes, Sinéad, et al. (2025). De-escalating and discontinuing disease-modifying therapies in multiple sclerosis [Journal-article]. Brain, 148(5), 1459–1478. https://doi.org/10.1093/brain/awae409

Müller, Jannis, Sharmin, Sifat, Lorscheider, Johannes, Horakova, Dana, Kubala Havrdova, Eva, Eichau, Sara, Patti, Francesco, Grammond, Pierre, Buzzard, Katherine, Skibina, Olga, Prat, Alexandre, Girard, Marc, Grand’Maison, Francois, Alroughani, Raed, Lechner-Scott, Jeannette, Spitaleri, Daniele, Barnett, Michael, Cartechini, Elisabetta, Sa, Maria Jose, et al. (2025). Treatment De-escalation in Relapsing-Remitting Multiple Sclerosis: An Observational Study. CNS Drugs, 39(4), 403–416. https://doi.org/10.1007/s40263-025-01164-w

Muraro, Paolo A., Mariottini, Alice, Greco, Raffaella, Burman, Joachim, Iacobaeus, Ellen, Inglese, Matilde, Snowden, John A., Alexander, Tobias, Amato, Maria Pia, Bø, Lars, Boffa, Giacomo, Ciccarelli, Olga, Cohen, Jeffrey A., Derfuss, Tobias, Farge, Dominique, Freedman, Mark S., Gaughan, Maria, Heesen, Christoph, Kazmi, Majid, et al. (2025). Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis and neuromyelitis optica spectrum disorder — recommendations from ECTRIMS and the EBMT [Journal-article]. Nature Reviews Neurology, 21(3), 140–158. https://doi.org/10.1038/s41582-024-01050-x

Wiendl, Heinz, Barkhof, Frederik, Montalban, Xavier, Achiron, Anat, Derfuss, Tobias, Chan, Andrew, Hodgkinson, Suzanne, Prat, Alexandre, Leocani, Letizia, Schmierer, Klaus, Sellebjerg, Finn, Vermersch, Patrick, Jin, Hulin, Chudecka, Anita, Kloetgen, Andreas, Lin, Dongdong, Gardner, Lidia, & De Stefano, Nicola. (2025). Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study. Frontiers in Immunology, 16. https://doi.org/10.3389/fimmu.2025.1512189

Oechtering, Johanna, Schaedelin, Sabine Anna, Stein, Kerstin, Maceski, Aleksandra Maleska, Melie-Garcia, Lester, Benkert, Pascal, Cagol, Alessandro, Leber, Selina, Galbusera, Riccardo, Ruberte, Esther, Hu, Wayne, Qureshi, Ferhan, Orleth, Annette, Demuth, Lilian, Willemse, Eline, Heijnen, Ingmar, Regeniter, Axel, Derfuss, Tobias J., Fischer-Barnicol, Bettina, et al. (2025). Aberrant Complement Activation Is Associated With Structural Brain Damage in Multiple Sclerosis. Neurology: Neuroimmunology and NeuroInflammation, 12(2). https://doi.org/10.1212/nxi.0000000000200361

Ayroza Galvão Ribeiro Gomes, Ana Beatriz, Kim, Su-Hyun, Pretzsch, Roxanne, Kulsvehagen, Laila, Schaedelin, Sabine, Lerner, Jasmine, Wetzel, Nora Sandrine, Benkert, Pascal, Maceski, Aleksandra Maleska, Hyun, Jae-Won, Lecourt, Anne-Catherine, Lipps, Patrick, Schoeps, Vinicius Andreoli, De Moura Brasil Matos, Aline, Mendes, Natalia Trombini, Apóstolos-Pereira, Samira Luisa, Mehling, Matthias, Derfuss, Tobias, Kappos, Ludwig, et al. (2025). Neurofilament Light Chain as a Discriminator of Disease Activity Status in MOG Antibody-Associated Disease. Neurology: Neuroimmunology and NeuroInflammation, 12(1). https://doi.org/10.1212/nxi.0000000000200347

Benkert, Pascal, Maleska Maceski, Aleksandra, Schaedelin, Sabine, Oechtering, Johanna, Zadic, Amar, Vilchez Gomez, Juan Francisco, Melie‐Garcia, Lester, Cagol, Alessandro, Galbusera, Riccardo, Subramaniam, Suvitha, Lorscheider, Johannes, Galli, Edoardo, Mueller, Jannis, Fischer‐Barnicol, Bettina, Achtnichts, Lutz, Findling, Oliver, Lalive, Patrice H., Bridel, Claire, Uginet, Marjolaine, et al. (2025). Serum Glial Fibrillary Acidic Protein and Neurofilament Light Chain Levels Reflect Different Mechanisms of Disease Progression under B‐Cell Depleting Treatment in Multiple Sclerosis. Annals of Neurology, 97(1), 104–115. https://doi.org/10.1002/ana.27096

Disanto, Giulio, Schaedelin, Sabine, Oechtering, Johanna, Lorscheider, Johannes, Galbusera, Riccardo, Finkener, Sebastian, Achtnichts, Lutz, Lalive, Patrice, Müller, Stefanie, Pot, Caroline, Hoepner, Robert, Salmen, Anke, Zecca, Chiara, Hemkens, Lars G, D’Souza, Marcus, Fischer-Barnicol, Bettina, Du Pasquier, Renaud, Roth, Patrick, Yaldizli, Özgür, et al. (2025). Treatment persistence and clinical outcomes in patients starting B cell depleting therapies within the Swiss MS Cohort. Multiple Sclerosis Journal - Experimental, Translational and Clinical, 11. https://doi.org/10.1177/20552173251315457

Schmierer, Klaus, Wiendl, Heinz, Barkhof, Frederik, Montalban, Xavier, Achiron, Anat, Derfuss, Tobias, Chan, Andrew, Hodgkinson, Suzanne, Prat, Alexandre, Leocani, Letizia, Sellebjerg, Finn, Vermersch, Patrick, Jin, Hulin, Sponton, Laura, Chudecka, Anita, Gardner, Lidia, & De Stefano, Nicola. (2025). Clinical and mechanistic effects of cladribine in relapsing multiple sclerosis: 2-year results from the MAGNIFY-MS Study. Therapeutic Advances in Neurological Disorders, 18. https://doi.org/10.1177/17562864251351760

Janiaud, Perrine, Zecca, Chiara, Salmen, Anke, Benkert, Pascal, Schädelin, Sabine, Orleth, Annette, Demuth, Lilian, Maceski, Aleksandra Maleska, Granziera, Cristina, Oechtering, Johanna, Leppert, David, Derfuss, Tobias, Achtnichts, Lutz, Findling, Oliver, Roth, Patrick, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, et al. (2024). MultiSCRIPT-Cycle 1—a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial. Trials, 25(1). https://doi.org/10.1186/s13063-024-08454-6

Becher, Burkhard, Derfuss, Tobias, & Liblau, Roland. (2024). Targeting cytokine networks in neuroinflammatory diseases [Journal-article]. Nature Reviews Drug Discovery, 23(11), 862–879. https://doi.org/10.1038/s41573-024-01026-y

Greselin, Martina, Lu, Po-Jui, Melie-Garcia, Lester, Ocampo-Pineda, Mario, Galbusera, Riccardo, Cagol, Alessandro, Weigel, Matthias, de Oliveira Siebenborn, Nina, Ruberte, Esther, Benkert, Pascal, Müller, Stefanie, Finkener, Sebastian, Vehoff, Jochen, Disanto, Giulio, Findling, Oliver, Chan, Andrew, Salmen, Anke, Pot, Caroline, Bridel, Claire, et al. (2024). Contrast-Enhancing Lesion Segmentation in Multiple Sclerosis: A Deep Learning Approach Validated in a Multicentric Cohort. Bioengineering, 11. https://doi.org/10.3390/bioengineering11080858

Blant, Julie C., De Rossi, Nicola N., Gold, Ralf, Maurousset, Aude, Kraemer, Markus, Romero-Pinel, Lucía, Misu, Tatsuro, Ouallet, Jean-Christophe, Pallix Guyot, Maud, Gerevini, Simonetta, Bakirtzis, Christos, Piñar Morales, Raquel, Vlad, Benjamin, Karypidis, Panajotis, Moisset, Xavier, Derfuss, Tobias J., Jelcic, Ilijas, Martin-Blondel, Guillaume, Ayzenberg, Ilya, et al. (2024). Presentation and Outcome in S1P-RM and Natalizumab-Associated Progressive Multifocal Leukoencephalopathy: A Multicenter Cohort Study [Journal-article]. Neurology: Neuroimmunology and NeuroInflammation, 11(5). https://doi.org/10.1212/nxi.0000000000200281

Müller, Jannis, Roos, Izanne, Kalincik, Tomas, Lorscheider, Johannes, Galli, Edoardo, Benkert, Pascal, Schädelin, Sabine, Sharmin, Sifat, Einsiedler, Maximilian, Hänni, Peter, Schmid, Jürg, Kuhle, Jens, Derfuss, Tobias, Granziera, Cristina, Ziemssen, Tjalf, Siepmann, Timo, & Yaldizli, Özgür. (2024). Escalating to medium- versus high-efficacy disease modifying therapy after low-efficacy treatment in relapsing remitting multiple sclerosis. Brain and Behavior, 14(5). https://doi.org/10.1002/brb3.3498

Janiaud, Perrine, Zecca, Chiara, Salmen, Anke, Benkert, Pascal, Schädelin, Sabine, Orleth, Annette, Demuth, Lilian, Maceski, Aleksandra Maleska, Granziera, Cristina, Oechtering, Johanna, Leppert, David, Derfuss, Tobias, Achtnichts, Lutz, Findling, Oliver, Roth, Patrick, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, et al. (2024). MultiSCRIPT-Cycle 1- A Pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in Multiple Sclerosis: a study protocol for a randomized clinical trial [Posted-content]. In medRxiv (Cold Spring Harbor Laboratory). Cold Spring Harbor Laboratory. https://doi.org/10.1101/2024.03.22.24304720

Callegari, Ilaria, Oechtering, Johanna, Schneider, Mika, Perriot, Sylvain, Mathias, Amandine, Voortman, Margarete M., Cagol, Alessandro, Lanner, Ulrike, Diebold, Martin, Holdermann, Sebastian, Kreiner, Victor, Becher, Burkhard, Granziera, Cristina, Junker, Andreas, Pasquier, Renaud Du, Khalil, Michael, Kuhle, Jens, Kappos, Ludwig, Sanderson, Nicholas S.R., & Derfuss, Tobias. (2024). Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5. Brain, 147(3), 839–848. https://doi.org/10.1093/brain/awad424

Oechtering, Johanna, Stein, Kerstin, Schaedelin, Sabine A., Maceski, Aleksandra M., Orleth, Annette, Meier, Stephanie, Willemse, Eline, Qureshi, Ferhan, Heijnen, Ingmar, Regeniter, Axel, Derfuss, Tobias, Benkert, Pascal, D’Souza, Marcus, Limberg, Marguerite, Fischer-Barnicol, Bettina, Achtnichts, Lutz, Mueller, Stefanie, Salmen, Anke, Lalive, Patrice H., et al. (2024). Complement Activation Is Associated With Disease Severity in Multiple Sclerosis [Journal-article]. Neurology: Neuroimmunology and NeuroInflammation, 11(2). https://doi.org/10.1212/nxi.0000000000200212

Ulutekin, Can, Galli, Edoardo, Schreiner, Bettina, Khademi, Mohsen, Callegari, Ilaria, Piehl, Fredrik, Sanderson, Nicholas, Kirschenbaum, Daniel, Mundt, Sarah, Filippi, Massimo, Furlan, Roberto, Olsson, Tomas, Derfuss, Tobias, Ingelfinger, Florian, & Becher, Burkhard. (2024). B cell depletion attenuates CD27 signaling of T helper cells in multiple sclerosis. Cell Reports Medicine, 5. https://doi.org/10.1016/j.xcrm.2023.101351

Cagol, Alessandro, Benkert, Pascal, Melie-Garcia, Lester, Schaedelin, Sabine A., Leber, Selina, Tsagkas, Charidimos, Barakovic, Muhamed, Galbusera, Riccardo, Lu, Po-Jui, Weigel, Matthias, Ruberte, Esther, Radue, Ernst-Wilhelm, Yaldizli, Özgür, Oechtering, Johanna, Lorscheider, Johannes, D’Souza, Marcus, Fischer-Barnicol, Bettina, Muller, Stefanie, Achtnichts, Lutz, et al. (2024). Association of Spinal Cord Atrophy and Brain Paramagnetic Rim Lesions With Progression Independent of Relapse Activity in People With MS. Neurology, 102(1). https://doi.org/10.1212/wnl.0000000000207768

Derfuss, Tobias, Bermel, Robert, Lin, Chien-Ju, Hauser, Stephen L., Kappos, Ludwig, Vollmer, Timothy, Comi, Giancarlo, Giovannoni, Gavin, Hartung, Hans-Peter, Weber, Martin S., Wang, Jianmei, Jessop, Nikki, Chognot, Cathy, Craveiro, Licinio, & Bar-Or, Amit. (2024). Long-term analysis of infections and associated risk factors in patients with multiple sclerosis treated with ocrelizumab: pooled analysis of 13 interventional clinical trials [Journal-article]. Therapeutic Advances in Neurological Disorders, 17. https://doi.org/10.1177/17562864241277736

Kulsvehagen, Laila, Woelfle, Tim, Ayroza Galvão Ribeiro Gomes, Ana Beatriz, Lipps, Patrick, Neziraj, Tradite, Flammer, Julia, Leuzinger, Karoline, Derfuss, Tobias, Kuhle, Jens, Papadopoulou, Athina, & Pröbstel, Anne-Katrin. (2024). Case report: Concurrent MOG antibody-associated disease and latent infections in two patients. Frontiers in Immunology, 15. https://doi.org/10.3389/fimmu.2024.1455355

Abdelhak, Ahmed, Benkert, Pascal, Schaedelin, Sabine, Boscardin, W. John, Cordano, Christian, Oechtering, Johanna, Ananth, Kirtana, Granziera, Cristina, Melie-Garcia, Lester, Montes, Shivany Condor, Beaudry-Richard, Alexandra, Achtnichts, Lutz, Oertel, Frederike C., Lalive, Patrice H., Leppert, David, Müller, Stefanie, Henry, Roland G., Pot, Caroline, Matthias, Amandine, et al. (2023). Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis [Journal-article]. JAMA Neurology, 80(12), 1317–1325. https://doi.org/10.1001/jamaneurol.2023.3997

Müller, Jannis, Schädelin, Sabine, Lorscheider, Johannes, Benkert, Pascal, Hänni, Peter, Schmid, Jürg, Kuhle, Jens, Derfuss, Tobias, Granziera, Cristina, & Yaldizli, Özgür. (2023). Comparative analysis of dimethyl fumarate and teriflunomide in relapsing–remitting multiple sclerosis. European Journal of Neurology, 30(12), 3809–3818. https://doi.org/10.1111/ene.16044

Müller, Jannis, Cagol, Alessandro, Lorscheider, Johannes, Tsagkas, Charidimos, Benkert, Pascal, Yaldizli, Özgür, Kuhle, Jens, Derfuss, Tobias, Sormani, Maria Pia, Thompson, Alan, Granziera, Cristina, & Kappos, Ludwig. (2023). Harmonizing Definitions for Progression Independent of Relapse Activity inMultiple Sclerosis A Systematic Review. JAMA Neurology, 80(11), 1232–1245. https://doi.org/10.1001/jamaneurol.2023.3331

Cerdá-Fuertes, Nuria, Stoessel, Marc, Mickeliunas, Gintaras, Pless, Silvan, Cagol, Alessandro, Barakovic, Muhamed, Maceski, Aleksandra M., Álvarez González, Cesar, D’ Souza, Marcus, Schaedlin, Sabine, Benkert, Pascal, Calabrese, Pasquale, Gugleta, Konstantin, Derfuss, Tobias, Sprenger, Till, Granziera, Cristina, Naegelin, Yvonne, Kappos, Ludwig, Kuhle, Jens, & Papadopoulou, Athina. (2023). Optical coherence tomography versus other biomarkers: Associations with physical and cognitive disability in multiple sclerosis. Multiple Sclerosis Journal, 29(13), 1540–1550. https://doi.org/10.1177/13524585231198760

Ayroza Galvão Ribeiro Gomes, Ana Beatriz, Kulsvehagen, Laila, Lipps, Patrick, Cagol, Alessandro, Cerdá-Fuertes, Nuria, Neziraj, Tradite, Flammer, Julia, Lerner, Jasmine, Lecourt, Anne-Catherine, De Oliveira S. Siebenborn, Nina, Cortese, Rosa, Schaedelin, Sabine, Andreoli Schoeps, Vinicius, De Moura Brasil Matos, Aline, Trombini Mendes, Natalia, Dos Reis Pereira, Clarissa, Ribeiro Monteiro, Mario Luiz, Dos Apóstolos-Pereira, Samira Luisa, Schindler, Patrick, et al. (2023). Immunoglobulin A Antibodies Against Myelin Oligodendrocyte Glycoprotein in a Subgroup of Patients with Central Nervous System Demyelination. JAMA Neurology, 80, 989–995. https://doi.org/10.1001/jamaneurol.2023.2523

Todea, Alexandra Ramona, Melie-Garcia, Lester, Barakovic, Muhamed, Cagol, Alessandro, Rahmanzadeh, Reza, Galbusera, Riccardo, Lu, Po-Jui, Weigel, Matthias, Ruberte, Esther, Radue, Ernst-Wilhelm, Schaedelin, Sabine, Benkert, Pascal, Oezguer, Yaldizli, Sinnecker, Tim, Müller, Stefanie, Achtnichts, Lutz, Vehoff, Jochen, Disanto, Giulio, Findling, Oliver, et al. (2023). A Multicenter Longitudinal MRI Study Assessing LeMan-PV Software Accuracy in the Detection of White Matter Lesions in Multiple Sclerosis Patients. Journal of Magnetic Resonance Imaging, 58, 864–876. https://doi.org/10.1002/jmri.28618

Touil, Hanane, Roostaei, Tina, Calini, Daniela, Diaconu, Claudiu, Epstein, Samantha, Raposo, Catarina, Onomichi, Kaho, Thakur, Kiran T., Craveiro, Licinio, Callegari, Ilaria, Bryois, Julien, Riley, Claire S., Menon, Vilas, Derfuss, Tobias, De Jager, Philip L., & Malhotra, Dheeraj. (2023). A structured evaluation of cryopreservation in generating single-cell transcriptomes from cerebrospinal fluid. Cell Reports Methods, 3(7). https://doi.org/10.1016/j.crmeth.2023.100533

Filippidis, Paraskevas, Damas, Jose, Viala, Benjamin, Assal, Frederic, Nawej Tshikung, Olivier, Tarr, Philip, Derfuss, Tobias, Oberholzer, Michael, Jelcic, Ilijas, Hundsberger, Thomas, Sacco, Leonardo, Cavassini, Matthias, Du Pasquier, Renaud, & Darling, Katharine E.A. (2023). Cerebrospinal Fluid HIV-1 Escape in Patients with Neurocognitive Symptoms: Pooled Data from a Neuro-HIV Platform and the NAMACO Study. Journal of Acquired Immune Deficiency Syndromes, 93(3), 219–228. https://doi.org/10.1097/qai.0000000000003189

Meier, Stephanie, Willemse, Eline A.J., Schaedelin, Sabine, Oechtering, Johanna, Lorscheider, Johannes, Melie-Garcia, Lester, Cagol, Alessandro, Barakovic, Muhamed, Galbusera, Riccardo, Subramaniam, Suvitha, Barro, Christian, Abdelhak, Ahmed, Thebault, Simon, Achtnichts, Lutz, Lalive, Patrice, Müller, Stefanie, Pot, Caroline, Salmen, Anke, Disanto, Giulio, et al. (2023). Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis. JAMA Neurology, 80(3), 287–297. https://doi.org/10.1001/jamaneurol.2022.5250

Granziera, Cristina, Derfuss, Tobias, & Kappos, Ludwig. (2023). Time to Change the Current Clinical Classification of Multiple Sclerosis? JAMA Neurology, 80(2), 128–130. https://doi.org/10.1001/jamaneurol.2022.4156

Wiendl, Heinz, Schmierer, Klaus, Hodgkinson, Suzanne, Derfuss, Tobias, Chan, Andrew, Sellebjerg, Finn, Achiron, Anat, Montalban, Xavier, Prat, Alexandre, De Stefano, Nicola, Barkhof, Frederik, Leocani, Letizia, Vermersch, Patrick, Chudecka, Anita, Mwape, Claire, Holmberg, Kristina H., Boschert, Ursula, & Roy, Sanjeev. (2023). Specific Patterns of Immune Cell Dynamics May Explain the Early Onset and Prolonged Efficacy of Cladribine Tablets: A MAGNIFY-MS Substudy. Neurology: Neuroimmunology and NeuroInflammation, 10(1). https://doi.org/10.1212/nxi.0000000000200048

Cerdá-Fuertes, Nuria, Nagy, Sara, Schaedelin, Sabine, Sinnecker, Tim, Ruberte, Esther, Papadopoulou, Athina, Würfel, Jens, Kuhle, Jens, Yaldizli, Özgür, Kappos, Ludwig, Derfuss, Tobias, & Décard, Bernhard F. (2023). Evaluation of frequency, severity, and independent risk factors for recurrence of disease activity after fingolimod discontinuation in a large real-world cohort of patients with multiple sclerosis. Therapeutic Advances in Neurological Disorders, 16. https://doi.org/10.1177/17562864221150312

Friedli, Christoph, Salmen, Anke, Hoepner, Robert, Achtnichts, Lutz, Bigi, Sandra, Derfuss, Tobias, Gobbi, Claudio, Kamber, Nicole, Kamm, Christian P., Kuhle, Jens, Lalive, Patrice, Müller, Stefanie, Papadopoulou, Athina, Pot, Caroline, Zecca, Chiara, Chan, Andrew, & on behalf of the Scientific Advisory Board of the Swiss Multiple Sclerosis Society and the Swiss Neurological Society. (2023). Specific Aspects of Immunotherapy for Multiple Sclerosis in Switzerland—A Structured Commentary, Update 2022. Clinical and Translational Neuroscience, 7(1). https://doi.org/10.3390/ctn7010002

Borriello F, Pasquarelli N, Law L, Rand K, Raposo C, Wei W, Craveiro L, & Derfuss T. (2022). Normal B-cell ranges in infants: A systematic review and meta-analysis. Journal of Allergy and Clinical Immunology, 150(5), 1216–1224. https://doi.org/10.1016/j.jaci.2022.06.006

Rose, Natalie, Holdermann, Sebastian, Callegari, Ilaria, Kim, Hyein, Fruh, Isabelle, Kappos, Ludwig, Kuhle, Jens, Müller, Matthias, Sanderson, Nicholas S. R., & Derfuss, Tobias. (2022). Receptor clustering and pathogenic complement activation in myasthenia gravis depend on synergy between antibodies with multiple subunit specificities. Acta Neuropathologica, 144(5), 1005–1025. https://doi.org/10.1007/s00401-022-02493-6

Jakeman, Bernadette, Scherrer, Alexandra U., Darling, Katharine E.A., Damas, Jose, Bieler-Aeschlimann, Melanie, Hasse, Barbara, Schlosser, Ladina, Hachfeld, Anna, Gutbrod, Klemens, Tarr, Philip E., Calmy, Alexandra, Assal, Frederic, Kunze, Ursula, Stoeckle, Marcel, Schmid, Patrick, Toller, Gianina, Rossi, Stefania, di Benedetto, Caroline, du Pasquier, Renaud, et al. (2022). Anticholinergic and Sedative Medications Are Associated With Neurocognitive Performance of Well Treated People With Human Immunodeficiency Virus. Open Forum Infectious Diseases, 9(9). https://doi.org/10.1093/ofid/ofac457

Yaldizli Ö, & Derfuss T. (2022). All Bruton’s tyrosine kinase inhibitors have similar efficacy and risks: Commentary (Patent No. 10). Multiple Sclerosis Journal, 28(10), Article 10. https://doi.org/10.1177/13524585221097562

Diebold, Martin, Galli, Edoardo, Kopf, Andreas, Sanderson, Nicholas S.R., Callegari, Ilaria, Benkert, Pascal, Nuñez, Nicolas Gonzalo, Ingelfinger, Florian, Herms, Stefan, Cichon, Sven, Kappos, Ludwig, Kuhle, Jens, Becher, Burkhard, Claassen, Manfred, & Derfuss, Tobias. (2022). High-dimensional immune profiling identifies a biomarker to monitor dimethyl fumarate response in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America, 119(31). https://doi.org/10.1073/pnas.2205042119

Tur C, Dubessy AL, Otero-Romero S, Amato MP, Derfuss T, Di Pauli F, Iacobaeus E, Mycko M, Abboud H, Achiron A, Bellinvia A, Boyko A, Casanova JL, Clifford D, Dobson R, Farez MF, Filippi M, Fitzgerald KC, Fonderico M, et al. (2022). The risk of infections for multiple sclerosis and neuromyelitis optica spectrum disorder disease-modifying treatments: Eighth European Committee for Treatment and Research in Multiple Sclerosis Focused Workshop Review. April 2021. Multiple Sclerosis Journal, 28(9), 1424–1456. https://doi.org/10.1177/13524585211069068

de Stefano N, Barkhof F, Montalban X, Achiron A, Derfuss T, Chan A, Hodgkinson S, Prat A, Leocani L, Schmierer K, Sellebjerg F, Vermersch P, Wiendl H, Keller B, Roy S, & MAGNIFY-MS Study Group. (2022). Early Reduction of MRI Activity During 6 Months of Treatment With Cladribine Tablets for Highly Active Relapsing Multiple Sclerosis: MAGNIFY-MS. Neurology: Neuroimmunology and NeuroInflammation, 9(4). https://doi.org/10.1212/nxi.0000000000001187

Callegari, Ilaria, Schneider, Mika, Berloffa, Giuliano, Mühlethaler, Tobias, Holdermann, Sebastian, Galli, Edoardo, Roloff, Tim, Boss, Renate, Infanti, Laura, Khanna, Nina, Egli, Adrian, Buser, Andreas, Zimmer, Gert, Derfuss, Tobias, & Sanderson, Nicholas S R. (2022). Potent neutralization by monoclonal human IgM against SARS-CoV-2 is impaired by class switch. EMBO Reports, 23(7). https://doi.org/10.15252/embr.202153956

Cagol, Alessandro, Schaedelin, Sabine, Barakovic, Muhamed, Benkert, Pascal, Todea, Ramona-Alexandra, Rahmanzadeh, Reza, Galbusera, Riccardo, Lu, Po-Jui, Weigel, Matthias, Melie-Garcia, Lester, Ruberte, Esther, Siebenborn, Nina, Battaglini, Marco, Radue, Ernst-Wilhelm, Yaldizli, Özgür, Oechtering, Johanna, Sinnecker, Tim, Lorscheider, Johannes, Fischer-Barnicol, Bettina, et al. (2022). Association of Brain Atrophy with Disease Progression Independent of Relapse Activity in Patients with Relapsing Multiple Sclerosis. JAMA Neurology, 79, 682–692. https://doi.org/10.1001/jamaneurol.2022.1025

Oechtering, Johanna, Lincke, Therese, Schaedelin, Sabine, Décard, Bernhard F., Maceski, Aleksandra, Orleth, Annette, Meier, Stephanie, Willemse, Eline, Buchmann, Arabella, Khalil, Michael, Derfuss, Tobias, Benkert, Pascal, Heijnen, Ingmar, Regeniter, Axel, Müller, Stefanie, Achtnichts, Lutz, Lalive, Patrice, Salmen, Anke, Pot, Caroline, et al. (2022). Intrathecal IgM Synthesis Is Associated with Spinal Cord Manifestation and Neuronal Injury in Early MS. Annals of Neurology, 91(6), 814–820. https://doi.org/10.1002/ana.26348

Müller, Jannis, Sinnecker, Tim, Wendebourg, Maria Janina, Schläger, Regina, Kuhle, Jens, Schädelin, Sabine, Benkert, Pascal, Derfuss, Tobias, Cattin, Philippe, Jud, Christoph, Spiess, Florian, Amann, Michael, Lincke, Therese, Barakovic, Muhamed, Cagol, Alessandro, Tsagkas, Charidimos, Parmar, Katrin, Pröbstel, Anne-Katrin, Reimann, Sophia, et al. (2022). Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder: A Retrospective, Cross-sectional Analysis. Neurology: Neuroimmunology and NeuroInflammation, 9(3). https://doi.org/10.1212/nxi.0000000000001147

Diebold, Martin, Galli, Edoardo, Kopf, Andreas, Sanderson, Nicholas, Callegari, Ilaria, Ingelfinger, Florian, Núñez, Nicolás Gonzalo, Benkert, Pascal, Kappos, Ludwig, Kuhle, Jens, Becher, Burkhard, Claassen, Manfred, & Derfuss, Tobias. (2022). Immunological Predictors of Dimethyl Fumarate-Induced Lymphopenia. Annals of Neurology, 91(5), 676–681. https://doi.org/10.1002/ana.26328

Benkert, Pascal, Meier, Stephanie, Schaedelin, Sabine, Manouchehrinia, Ali, Yaldizli, Özgür, Maceski, Aleksandra, Oechtering, Johanna, Achtnichts, Lutz, Conen, David, Derfuss, Tobias, Lalive, Patrice H., Mueller, Christian, Müller, Stefanie, Naegelin, Yvonne, Oksenberg, Jorge R., Pot, Caroline, Salmen, Anke, Willemse, Eline, Kockum, Ingrid, et al. (2022). Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study. The Lancet Neurology, 21(3), 246–257. https://doi.org/10.1016/s1474-4422(22)00009-6

Filippi M., Danesi R., Derfuss T., Duddy M., Gallo P., Gold R., Havrdova E.K., Kornek B., Sacca F., Tintore M., Weber J., & Trojano M. (2022). Early and unrestricted access to high-efficacy disease-modifying therapies: a consensus to optimize benefits for people living with multiple sclerosis. Journal of Neurology, 269(3), 1670–1677. https://doi.org/10.1007/s00415-021-10836-8

Hartung HP, Derfuss T., Cree B.A.C., Sormani M.P., Selmaj K., Stutters J, Prados F, MacManus D., Schneble HM, Lambert E., Porchet H, Glanzman R., Warne D, Curtin F., Kornmann G., Buffet B, Kremer D, Kury P., Leppert D, et al. (2022). Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study. Multiple Sclerosis Journal, 28(3), 429–440. https://doi.org/10.1177/13524585211024997

Diebold, Martin, Meola, Marco, Purushothaman, Srinithi, Siewert, Lena K, Pössnecker, Elisabeth, Roloff, Tim, Lindberg, Raija LP, Kuhle, Jens, Kappos, Ludwig, Derfuss, Tobias, Egli, Adrian, & Pröbstel, Anne-Katrin. (2022). Gut microbiota composition as a candidate risk factor for dimethyl fumarate-induced lymphopenia in multiple sclerosis. Gut Microbes, 14(1). https://doi.org/10.1080/19490976.2022.2147055

Müller, J., Reimann, S., Sinnecker, T., Wendebourg, M.J., Schläger, R., Tsagkas, C., Parmar, K., Pröbstel, A.-K., Amann, M., Würfel, J., Hadjikhani, N., Lincke, T., Barakovic, M., Cagol, A., Melie-Garcia, L., Meier, S., Maceski, A., Willemse, E., Leppert, D., et al. (2022, January 1). On the association between the choroid plexus volume and disease characteristics in multiple sclerosis. In Multiple Sclerosis Journal. SAGE Publications.

Portaccio E., Fonderico M., Hemmer B., Derfuss T., Stankoff B., Selmaj K., Tintore M., & Amato M.P. (2022). Impact of COVID-19 on multiple sclerosis care and management: Results from the European Committee for Treatment and Research in Multiple Sclerosis survey. Multiple Sclerosis Journal, 28(1), 132–138. https://doi.org/10.1177/13524585211005339

Sinnecker, Tim, Schädelin, Sabine, Benkert, Pascal, Ruberte, Esther, Amann, Michael, Lieb, Johanna M., Naegelin, Yvonne, Müller, Jannis, Kuhle, Jens, Derfuss, Tobias, Kappos, Ludwig, Wuerfel, Jens, Granziera, Cristina, & Yaldizli, Özgür. (2022). Brain atrophy measurement over a MRI scanner change in multiple sclerosis. NeuroImage: Clinical, 36. https://doi.org/10.1016/j.nicl.2022.103148

Cagol, A., Schaedelin, S., Barakovic, M., Benkert, P., Todea, R. -A., Rahmanzadeh, R., Galbusera, R., Lu, P. -J., Weigel, M., Melie-Garcia, L., Ruberte, E., Radue, E. -W., Yaldizli, O., Oechtering, J., Sinnecker, T., Lorscheider, J., Mueller, S., Achtnichts, L., Vehoff, J., et al. (2021). Progression independent of relapse activity is associated with increased brain atrophy rates in patients with relapsing-remitting multiple sclerosis. Multiple Sclerosis Journal, 27(2), 98–99.

Liebmann M, Korn L, Janoschka C, Albrecht S, Lauks S, Herrmann AM, Schulte-Mecklenbeck A, Schwab N, Schneider-Hohendorf T, Eveslage M, Wildemann B, Luessi F, Schmidt S, Diebold M, Bittner S, Gross CC, Kovac S, Zipp F, Derfuss T, et al. (2021). Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity. Brain, 144(10), 3126–3141. https://doi.org/10.1093/brain/awab307

Marignier R., Hacohen Y, Cobo-Calvo A., Pröbstel AK, Aktas O., Alexopoulos H, Amato M.-P., Asgari N., Banwell B., Bennett J, Brilot F., Capobianco M., Chitnis T., Ciccarelli O., Deiva K., De Seze J., Fujihara K., Jacob A, Kim H.J., et al. (2021). Myelin-oligodendrocyte glycoprotein antibody-associated disease. The Lancet Neurology, 20(9), 762–772. https://doi.org/10.1016/s1474-4422(21)00218-0

Oechtering, Johanna, Schaedelin, Sabine, Benkert, Pascal, Müller, Stefanie, Achtnichts, Lutz, Vehoff, Jochen, Disanto, Giulio, Findling, Oliver, Fischer-Barnicol, Bettina, Orleth, Annette, Chan, Andrew, Pot, Caroline, Barakovic, Muhamed, Rahmanzadeh, Reza, Galbusera, Riccardo, Heijnen, Ingmar, Lalive, Patrice H., Wuerfel, Jens, Subramaniam, Suvitha, et al. (2021). Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis. Annals of Neurology, 90, 477–489. https://doi.org/10.1002/ana.26137

Wiendl H., Gold R, Berger T, Derfuss T., Linker R., Mäurer M, Stangel M., Aktas O., Baum K., Berghoff M., Bittner S., Chan A., Czaplinski A, Deisenhammer F., DiPauli F., DuPasquier R., Enzinger C, Fertl E., Gass A., et al. (2021). Multiple sclerosis treatment consensus group (MSTCG): position paper on disease-modifying treatment of multiple sclerosis 2021 (white paper) Multiple Sklerose Therapie Konsensus Gruppe (MSTKG): Positionspapier zur verlaufsmodifizierenden Therapie der Multiplen Sklerose 2021 (White Paper). Nervenarzt, 92(8), 773–801. https://doi.org/10.1007/s00115-021-01157-2

Santos, Galia, Locatelli, Isabella, Métral, Mélanie, Berney, Alexandre, Nadin, Isaure, Calmy, Alexandra, Tarr, Philip, Gutbrod, Klemens, Hauser, Christoph, Brugger, Peter, Kovari, Helen, Kunze, Ursi, Stoeckle, Marcel, Früh, Severin, Schmid, Patrick, Rossi, Stefania, Di Benedetto, Caroline, Du Pasquier, Renaud, Darling, Katharine, et al. (2021). The association between depressive symptoms and neurocognitive impairment in people with well-treated HIV in Switzerland. International Journal of STD and AIDS, 32(8), 729–739. https://doi.org/10.1177/0956462420987434

Allum, J.H.J., Rust, H.M., Lutz, N., Schouenborg, C., Fischer-Barnicol, B., Haller, V., Derfuss, T., Kuhle, J., & Yaldizli, Ö. (2021). Characteristics of improvements in balance control using vibro-tactile biofeedback of trunk sway for multiple sclerosis patients. Journal of the Neurological Sciences, 425. https://doi.org/10.1016/j.jns.2021.117432

Callegari, Ilaria, Derfuss, Tobias, & Galli, Edoardo. (2021). Update on treatment in multiple sclerosis. Presse Medicale, 50(2). https://doi.org/10.1016/j.lpm.2021.104068

Johansson, David, Rauld, Celine, Roux, Julien, Regairaz, Camille, Galli, Edoardo, Callegari, Ilaria, Raad, Layla, Waldt, Annick, Cuttat, Rachel, Roma, Guglielmo, Diebold, Martin, Becher, Burkhard, Kuhle, Jens, Derfuss, Tobias, Carballido, Jose M., & Sanderson, Nicholas S.R. (2021). Mass Cytometry of CSF Identifies an MS-Associated B-cell Population. Neurology: Neuroimmunology and NeuroInflammation, 8(2), e943. https://doi.org/10.1212/nxi.0000000000000943

Darling KEA, Locatelli I, Benghalem N., Nadin I, Calmy A., Gutbrod K, Hauser C., Brugger P, Hasse B, Kovari H., Kunze U., Stoeckle M, Fux C, Rossi S., Di Benedetto C., Fruh S., Schmid P., Tarr PE, Daeppen J.-B., et al. (2021). Alcohol consumption and neurocognitive deficits in people with well-treated HIV in Switzerland. PLoS ONE, 16(3 March). https://doi.org/10.1371/journal.pone.0246579

Lorscheider J, Benkert P, Lienert C, Hänni P, Derfuss T, Kuhle J, Kappos L., & Yaldizli Ö. (2021). Comparative analysis of dimethyl fumarate and fingolimod in relapsing–remitting multiple sclerosis. Journal of Neurology, 268(3), 941–949. https://doi.org/10.1007/s00415-020-10226-6

von Wyl V, Benkert P, Moser A, Lorscheider J, Décard B, Hänni P, Lienert C, Kuhle J, Derfuss T, Kappos L, & Yaldizli Ö. (2021). Disability progression in relapse-free multiple sclerosis patients on fingolimod versus interferon-beta/glatiramer acetate. Multiple Sclerosis Journal, 27(3), 439–448. https://doi.org/10.1177/1352458520918489

Fischer-Barnicol, Bettina, Oechtering, Johanna, Kuhle, Jens, Lorscheider, Johannes, Kappos, Ludwig, & Derfuss, Tobias. (2021). Combination of teriflunomide and interferon as follow-up therapy after fingolimod-associated PML. Neurology(R) Neuroimmunology & Neuroinflammation, 8(1). https://doi.org/10.1212/nxi.0000000000000927

Wiendl H., Gold R, Berger T, Derfuss T., Linker R., Mäurer M, Aktas O., Baum K, Berghoff M., Bittner S., Chan A., Czaplinski A, Deisenhammer F., Di Pauli F., Du Pasquier R, Enzinger C., Fertl E., Gass A., Gehring K., et al. (2021). Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper). Therapeutic Advances in Neurological Disorders, 14. https://doi.org/10.1177/17562864211039648

Cree BAC, Cutter G., Wolinsky JS, Freedman M., Comi G., Giovannoni G., Hartung HP, Arnold D., Kuhle J, Block V., Munschauer F.E., Sedel F., Lublin FD, Reingold S., Duquette P., Derfuss T., Fazekas F., Sormani M.P., Lisak R.P., et al. (2020). Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet Neurology, 19(12), 988–997. https://doi.org/10.1016/s1474-4422(20)30347-1

Nagy S, Kuhle J, & Derfuss T. (2020). Lymphocyte recovery after fingolimod discontinuation in patients with MS. Neurology(R) Neuroimmunology & Neuroinflammation, 7(6). https://doi.org/10.1212/nxi.0000000000000874

Hässler S, Bachelet D, Duhaze J, Szely N, Gleizes A, Hacein-Bey Abina S, Aktas O, Auer M, Avouac J, Birchler M, Bouhnik Y, Brocq O, Buck-Martin D, Cadiot G, Carbonnel F, Chowers Y, Comabella M, Derfuss T, De Vries N, et al. (2020). Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium. PLoS Medicine, 17(10), e1003348. https://doi.org/10.1371/journal.pmed.1003348

Aliu, Butrint, Demeestere, Delphine, Seydoux, Emilie, Boucraut, José, Delmont, Emilien, Brodovitch, Alexandre, Oberholzer, Thomas, Attarian, Shahram, Théaudin, Marie, Tsouni, Pinelopi, Kuntzer, Thierry, Derfuss, Tobias, Steck, Andreas J., Ernst, Beat, Herrendorff, Ruben, & Hänggi, Pascal. (2020). Selective inhibition of anti-MAG IgM autoantibody binding to myelin by an antigen-specific glycopolymer. Journal of Neurochemistry, 154(5), 486–501. https://doi.org/10.1111/jnc.15021

Arrambide G., Iacobaeus E., Amato M.P., Derfuss T, Vukusic S., Hemmer B., Brundin L., Tintore M, Berger J., Boyko A., Brinar V., Brownlee W., Ciccarelli O., Coles A., Correale J., Cutter G., Edan G., Evangelou N., Fernandez O., et al. (2020). Aggressive multiple sclerosis (2): Treatment. Multiple Sclerosis Journal, 26(9), 1045–1063. https://doi.org/10.1177/1352458520924595

Iacobaeus E, Arrambide G, Amato MP, Derfuss T, Vukusic S, Hemmer B, Tintore M, Brundin L, 2018 ECTRIMS Focused Workshop Group., Boyko A., Brinar V., Brownlee W., Ciccarelli O., Coles A., Correale J., Cutter G., Edan G., Evangelou N., Fernandez O., et al. (2020). Aggressive multiple sclerosis (1): Towards a definition of the phenotype. Multiple Sclerosis Journal, 26(9), 1031–1044. https://doi.org/10.1177/1352458520925369

von Wyl V, Décard BF, Benkert P, Lorscheider J, Hänni P, Lienert C, Kuhle J, Derfuss T, Kappos L, & Yaldizli Ö. (2020). Influence of age at disease onset on future relapses and disability progression in patients with multiple sclerosis on immunomodulatory treatment. European Journal of Neurology, 27(6), 1066–1075. https://doi.org/10.1111/ene.14191

Metral, M., Nadin, I., Locatelli, I., Tarr, P.E., Calmy, Alexandra, Kovari, H., Brugger, P., Cusini, A., Gutbrod, K., Schmid, P., Schwind, M., Kunze, U., Di Benedetto, C., Pignatti, R., Du Pasquier, R., Darling, K.E.A., Cavassini, M., Cavassini, Matthias, Pasquier, Renaud Du, et al. (2020). How helpful are the European AIDS Clinical Society cognitive screening questions in predicting cognitive impairment in an aging, well-treated HIV-positive population? HIV Medicine, 21(5), 342–348. https://doi.org/10.1111/hiv.12828

Wendebourg MJ, Nagy S, Derfuss T, Parmar K, & Schlaeger R. (2020). Magnetic resonance imaging in immune-mediated myelopathies. Journal of Neurology, 267(5), 1233–1244. https://doi.org/10.1007/s00415-019-09206-2

Derfuss T, Mehling M, Papadopoulou A, Bar-Or A, Cohen JA, & Kappos L. (2020). Advances in oral immunomodulating therapies in relapsing multiple sclerosis. The Lancet Neurology, 19(4), 336–347. https://doi.org/10.1016/s1474-4422(19)30391-6

Benkert, P., Schaedelin, S., Maceski, A., Disanto, G., Oechtering, J., Barakovic, M., Orleth, A., Rey, D., Sinnecker, T., Yaldizli, O., Rahmanzadeh, R., Zadic, S., Galbusera, R., Todea, R. -A., Cagol, A., Achtnichts, L., Aeschbacher, S., Chan, A., Conen, D., et al. (2020). Serum nfl z-scores derived from a large healthy control group reflect different levels of treatment effect in a real-world setting. Multiple Sclerosis Journal, 26(3, Supplement), 194–195.

Cagol, A., Barakovic, M., Benkert, P., Todea, R. -A., Rahmanzadeh, R., Galbusera, R., Schaedelin, S., Lu, P. -J., Weigel, M., Radue, E. -W., Yaldizli, O., Lorscheider, J., Sinnecker, T., Fartaria, M. J., Mueller, S., Achtnichts, L., Vehoff, J., Disanto, G., Findling, O., et al. (2020). Focal inflammatory activity and lesion repair are associated with brain atrophy rates in MS patients. Multiple Sclerosis Journal, 26(3, Supplement), 395.

Derfuss T, Sastre-Garriga J, Montalban X, Rodegher M, Wuerfel J, Gaetano L, Tomic D, Azmon A, Wolf C, & Kappos L. (2020). The ACROSS study: Long-term efficacy of fingolimod in patients with relapsing–remitting multiple sclerosis. Multiple Sclerosis Journal - Experimental, Translational and Clinical, 6(1), 2055217320907951. https://doi.org/10.1177/2055217320907951

Sinnecker, Tim, Ruberte, Esther, Schädelin, Sabine, Canova, Vera, Amann, Michael, Naegelin, Yvonne, Penner, Iris-Katharina, Müller, Jannis, Kuhle, Jens, Décard, Bernhard, Derfuss, Tobias, Kappos, Ludwig, Granziera, Cristina, Wuerfel, Jens, Magon, Stefano, & Yaldizli, Özgür. (2020). New and enlarging white matter lesions adjacent to the ventricle system and thalamic atrophy are independently associated with lateral ventricular enlargement in multiple sclerosis [Journal-article]. Journal of Neurology, 267(1), 192–202. https://doi.org/10.1007/s00415-019-09565-w

Sinnecker, T., Ruberte, E., Yaldizli, O., Rahmanzadeh, R., Galbusera, R., Todea, R. -A., Cagol, A., Subramaniam, S., Benkert, P., Mueller, S., Achtnichts, L., Vehoff, J., Disanto, G., Findling, O., Chan, A., Salmen, A., Pot, C., Lalive, P., Zecca, C., et al. (2020). Role of gadolinium-based contrast agents to detect subclinical disease activity in clinically stable patients in the swiss MS cohort study. Multiple Sclerosis Journal, 26(3, Supplement), 422–423.

Diebold, Martin, Altersberger, Valerian, Décard, Bernhard F, Kappos, Ludwig, Derfuss, Tobias, & Lorscheider, Johannes. (2019). A case of progressive multifocal leukoencephalopathy under dimethyl fumarate treatment without severe lymphopenia or immunosenescence. Multiple Sclerosis Journal, 25, 1682–1685. https://doi.org/10.1177/1352458519852100

Diebold, Martin, Altersberger, Valerian, Décard, Bernhard F, Kappos, Ludwig, Derfuss, Tobias, & Lorscheider, Johannes. (2019). PML with dimethyl fumarate—No convincing case against natalizumab. Multiple Sclerosis Journal, 25, 1687–1688. https://doi.org/10.1177/1352458519872894

Diebold, Martin, Fischer-Barnicol, Bettina, Tsagkas, Charidimos, Kuhle, Jens, Kappos, Ludwig, Derfuss, Tobias, & Décard, Bernhard F. (2019). Hepatitis e virus infections in patients with MS on oral disease-modifying treatment. Neurology: Neuroimmunology and NeuroInflammation, 6(5). https://doi.org/10.1212/nxi.0000000000000594

Galli, Edoardo, Hartmann, Felix J., Schreiner, Bettina, Ingelfinger, Florian, Arvaniti, Eirini, Diebold, Martin, Mrdjen, Dunja, van der Meer, Franziska, Krieg, Carsten, Nimer, Faiez Al, Sanderson, Nicholas, Stadelmann, Christine, Khademi, Mohsen, Piehl, Fredrik, Claassen, Manfred, Derfuss, Tobias, Olsson, Tomas, & Becher, Burkhard. (2019). GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis. Nature Medicine, 25(8), 1290–1300. https://doi.org/10.1038/s41591-019-0521-4

Diebold M, Müller S, Derfuss T, & Décard BF. (2019). A case of concomitant psoriasis and multiple sclerosis: Secukinumab and rituximab exert dichotomous effects in two autoimmune conditions. Multiple Sclerosis and Related Disorders, 31, 38–40. https://doi.org/10.1016/j.msard.2019.03.009

Pasquier, Baptiste, Borisow, Nadja, Rasche, Ludwig, Bellmann-Strobl, Judith, Ruprecht, Klemens, Niendorf, Thoralf, Derfuss, Tobias J., Wuerfel, Jens, Paul, Friedemann, & Sinnecker, Tim. (2019). Quantitative 7T MRI does not detect occult brain damage in neuromyelitis optica. Neurology Neuroimmunology and Neuroinflammation, 6. https://doi.org/10.1212/nxi.0000000000000541

Pröbstel AK, Thanei M, Erni B, Lecourt AC, Branco L, André R, Roux-Lombard P, Koenig KF, Huynh-Do U, Ribi C, Chizzolini C, Kappos L, Trendelenburg M, Derfuss T, & Swiss Systemic Lupus Erythematosus Cohort Study Group. (2019). Association of antibodies against myelin and neuronal antigens with neuroinflammation in systemic lupus erythematosus. Rheumatology (United Kingdom), 58(5), 908–913. https://doi.org/10.1093/rheumatology/key282

Diebold M, & Derfuss T. (2019). The monoclonal antibody GNbAC1: targeting human endogenous retroviruses in multiple sclerosis. Therapeutic Advances in Neurological Disorders, 12, 1756286419833574. https://doi.org/10.1177/1756286419833574

Naegelin Y, Naegelin P, von Felten S, Lorscheider J, Sonder J, Uitdehaag BMJ, Scotti B, Zecca C, Gobbi C, Kappos L, & Derfuss T. (2019). Association of Rituximab Treatment with Disability Progression among Patients with Secondary Progressive Multiple Sclerosis. JAMA Neurology, 76(3), 274–281. https://doi.org/10.1001/jamaneurol.2018.4239