Prof. Dr. med. Diego Kyburz

Steimer, A., Götschi, A., Witte, T., Scherer, A., Brändli, J., Nissen, M. J., Möller, B., Grosswiler, S., Kyburz, D., Dan, D., Rubbert-Roth, A., Adler, S., Distler, O., Baraliakos, X., & Ciurea, A. (2025). Anti-CD74 autoantibodies in axial spondyloarthritis as biomarkers for activity and severity of disease but not for tumour necrosis factor inhibitor retention: data from the Swiss Clinical Quality Management in rheumatic diseases cohort. Clinical Rheumatology, 44(4), 1589–1596. https://doi.org/10.1007/s10067-025-07393-0

Kurth, S., Hanser, E., Haener Massimi, S., Giaglis, S., Geier, F., Burri, D., Buczak, K., Heider, U., Wild, S., Tiaden, A. N., & Kyburz, D. (2025). Identification and proteomic profiling of CD90+ small EVs using a refined immunocapture separation approach targeting stromal-derived EV subpopulations in synovial fluid of arthritis patients [Posted-content]. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2025.03.12.640750

Lehmann, Anouk, Vosbeck, Juerg, Kyburz, Diego, Hruz, Petr, & Niess, Jan Hendrik. (2024). Risankizumab and Certolizumab Pegol Dual-Targeted Therapy for Crohn’s Disease and Axial Spondyloarthritis: A Case Report. Case Reports in Gastroenterology, 19(1), 22–30. https://doi.org/10.1159/000542759

Lehmann, Julia, Giaglis, Stavros, Kyburz, Diego, Daoudlarian, Douglas, & Walker, Ulrich A. (2024). Plasma mtDNA as a possible contributor to and biomarker of inflammation in rheumatoid arthritis. Arthritis Research and Therapy, 26(1). https://doi.org/10.1186/s13075-024-03329-2

Poller, M., Schulz, M. M. P., Schulze-Koops, H., Kyburz, D., von Kempis, J., & Mueller, R. B. (2024). Does the Change of Weather Influence Disease Activity in Rheumatoid Arthritis Patients: Patients’ Self-Assessment via WebApp. Journal of Clinical Medicine, 13(17). https://doi.org/10.3390/jcm13175336

Hemmig AK, Aschwanden M, Berger CT, Kyburz D, Mensch N, Staub D, Stegert M, Imfeld S, & Daikeler T. (2024). Prior polymyalgia rheumatica is associated with sonographic vasculitic changes in newly diagnosed patients with giant cell arteritis. Rheumatology (United Kingdom), 63(6), 1523–1527. https://doi.org/10.1093/rheumatology/kead450

Hemmig, Andrea K., Rottenburger, Christof, Baruti, Luan, Mensch, Noemi, Aschwanden, Markus, Kyburz, Diego, Pradella, Maurice, Staub, Daniel, Stegert, Mihaela, Berger, Christoph T., Imfeld, Stephan, Sommer, Gregor, & Daikeler, Thomas. (2024). Imaging to predict early relapses after treatment discontinuation in patients with large vessel giant cell arteritis – A cohort study. Seminars in Arthritis and Rheumatism, 66. https://doi.org/10.1016/j.semarthrit.2024.152425

Trottet, C., Allam, A., Horvath, A. N., Finckh, A., Hügle, T., Adler, S., Kyburz, D., Micheroli, R., Krauthammer, M., & Ospelt, C. (2024). Explainable deep learning for disease activity prediction in chronic inflammatory joint diseases. PLOS Digital Health, 3(6). https://doi.org/10.1371/journal.pdig.0000422

Welsh, Joshua A., Goberdhan, Deborah C. I., O’Driscoll, Lorraine, Buzas, Edit I., Blenkiron, Cherie, Bussolati, Benedetta, Cai, Houjian, Di Vizio, Dolores, Driedonks, Tom A. P., Erdbrügger, Uta, Falcon-Perez, Juan M., Fu, Qing-Ling, Hill, Andrew F., Lenassi, Metka, Lim, Sai Kiang, Mahoney, M.ỹ.G., Mohanty, Sujata, Möller, Andreas, Nieuwland, Rienk, et al. (2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles, 13(2). https://doi.org/10.1002/jev2.12404

Ciurea, Adrian, Götschi, Andrea, Bräm, René, Bürki, Kristina, Exer, Pascale, Andor, Michael, Nissen, Michael J., Möller, Burkhard, Hügle, Thomas, Rubbert-Roth, Andrea, Kyburz, Diego, Distler, Oliver, Scherer, Almut, & Micheroli, Raphael. (2023). Early axial spondyloarthritis according to the ASAS consensus definition: characterisation of patients and effectiveness of a first TNF inhibitor in a large observational registry. RMD Open, 9(4). https://doi.org/10.1136/rmdopen-2023-003455

Hemmig, Andrea K., Rottenburger, Christof, Aschwanden, Markus, Berger, Christoph T., Kyburz, Diego, Pradella, Maurice, Staub, Daniel, Imfeld, Stephan, Sommer, Gregor, & Daikeler, Thomas. (2023). Magnetic Resonance Imaging Findings Corresponding to Vasculitis as Defined via [18F]FDG Positron Emission Tomography or Ultrasound. Diagnostics, 13(23). https://doi.org/10.3390/diagnostics13233559

Riek, Myriam, Scherer, Almut, Möller, Burkhard, Ciurea, Adrian, von Mühlenen, Ines, Gabay, Cem, Kyburz, Diego, Brulhart, Laure, von Kempis, Johannes, Mueller, Ruediger B., Hasler, Paul, Strahm, Tanja, von Känel, Sabine, Zufferey, Pascal, Dudler, Jean, & Finckh, Axel. (2023). Serious infection risk of tofacitinib compared to biologics in patients with rheumatoid arthritis treated in routine clinical care. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-44841-w

Micheroli, Raphael, Kissling, Seraphina, Bürki, Kristina, Möller, Burkhard, Finckh, Axel, Nissen, Michael J., Exer, Pascale, Bräm, René, Kyburz, Diego, Rubbert-Roth, Andrea, Andor, Michael, Baraliakos, Xenofon, de Hooge, Manouk, Distler, Oliver, Scherer, Almut, & Ciurea, Adrian. (2023). Anaemia is associated with higher disease activity in axial spondyloarthritis but is not an independent predictor of spinal radiographic progression: data from the Swiss Clinical Quality Management Registry. Clinical Rheumatology, 42(9), 2377–2385. https://doi.org/10.1007/s10067-023-06662-0

Giaglis, Stavros, Daoudlarian, Douglas, Thiel, Jens, Rizzi, Marta, Kyburz, Diego, Venhoff, Nils, & Walker, Ulrich A. (2023). Mitochondrial DNA: A novel indicator of active inflammation in ANCA-Associated vasculitides. Rheumatology (United Kingdom), 62(8), 2930–2937. https://doi.org/10.1093/rheumatology/kead015

Mensch, Noemi, Hemmig, Andrea Katharina, Aschwanden, Markus, Imfeld, Stephan, Stegert, Mihaela, Recher, Mike, Staub, Daniel, Kyburz, Diego, Berger, Christoph T, & Daikeler, Thomas. (2023). Rapid glucocorticoid tapering regimen in patients with giant cell arteritis: a single centre cohort study. RMD Open, 9(3). https://doi.org/10.1136/rmdopen-2023-003301

Hawtin, Stuart, André, Cédric, Collignon-Zipfel, Géraldine, Appenzeller, Simone, Bannert, Bettina, Baumgartner, Lea, Beck, Damian, Betschart, Claudia, Boulay, Thomas, Brunner, Hermine I., Ceci, Melanie, Deane, Jonathan, Feifel, Roland, Ferrero, Enrico, Kyburz, Diego, Lafossas, Frederique, Loetscher, Pius, Merz-Stoeckle, Christina, Michellys, Pierre, et al. (2023). Preclinical characterization of the Toll-like receptor 7/8 antagonist MHV370 for lupus therapy. Cell Reports Medicine, 4(5). https://doi.org/10.1016/j.xcrm.2023.101036

Fröhlich, Fabienne, Micheroli, Raphael, Hebeisen, Monika, Kissling, Seraphina, Bürki, Kristina, Exer, Pascale, Bräm, René, Niedermann, Karin, Möller, Burkhard, Nissen, Michael J., Kyburz, Diego, Andor, Michael, Distler, Oliver, Scherer, Almut, & Ciurea, Adrian. (2023). HLA-B27 as a predictor of effectiveness of treatment with TNF inhibitors in axial spondyloarthritis: data from the Swiss Clinical Quality Management Registry. Clinical Rheumatology, 42(5), 1267–1274. https://doi.org/10.1007/s10067-022-06490-8

Amstad A, Papagiannoulis E, Scherer A, Rubbert-Roth A, Finckh A, Mueller R, Dudler J, Möller B, Villiger PM, Schulz MMP, & Kyburz D. (2023). Comparison of drug retention of TNF inhibitors, other biologics and JAK inhibitors in RA patients who discontinued JAK inhibitor therapy. Rheumatology (United Kingdom), 62(1), 89–97. https://doi.org/10.1093/rheumatology/keac285

Hemmig, Andrea Katharina, Aschwanden, Markus, Seiler, Sabine, Berger, Christoph T., Köhn, Philipp, Kyburz, Diego, Mensch, Noemi, Staub, Daniel, Stegert, Mihaela, Imfeld, Stephan, & Daikeler, Thomas. (2023). Long delay from symptom onset to first consultation contributes to permanent vision loss in patients with giant cell arteritis: a cohort study. RMD Open, 9(1). https://doi.org/10.1136/rmdopen-2022-002866

Micheroli, Raphael, Bhatia, Sangeeta, Vallejo-Yagüe, Enriqueta, Burden, Andrea Michelle, Möller, Burkhard, Nissen, Michael J., Kyburz, Diego, Kissling, Seraphina, Distler, Oliver, Ospelt, Caroline, & Ciurea, Adrian. (2023). Obesity Represents a Persisting Health Issue in Axial Spondyloarthritis, Particularly Affecting Socially Disadvantaged Patients. Journal of Rheumatology, 50(12), 1587–1593. https://doi.org/10.3899/jrheum.2023-0137

Dräger, Sarah, Jahn, Kathleen, Vogt, Moritz, Hopfer, Helmut, Kyburz, Diego, & Osthoff, Michael. (2022). Reversed Halo Sign on Chest Computed Tomography in a 33-Year-Old Man Without Immunosuppression. American Journal of Medicine, 135(9), e318–e320. https://doi.org/10.1016/j.amjmed.2022.04.009

Van Hoovels L, Vander Cruyssen B, Sieghart D, Bonroy C, Nagy E, Pullerits R, Čučnik S, Dahle C, Heijnen I, Bernasconi L, Benkhadra F, Bogaert L, Van Den Bremt S, Van Liedekerke A, Vanheule G, Robbrecht J, Studholme L, Wirth C, Müller R, et al. (2022). IgA rheumatoid factor in rheumatoid arthritis. Clinical Chemistry and Laboratory Medicine, 60(10), 1617–1626. https://doi.org/10.1515/cclm-2022-0244

Ruocco A, Sirico A, Novelli R, Iannelli S, Van Breda SV, Kyburz D, Hasler P, Aramini A, & Amendola PG. (2022). The role of C5a-C5aR1 axis in bone pathophysiology: A mini-review. Frontiers in Cell and Developmental Biology, 10, 957800. https://doi.org/10.3389/fcell.2022.957800

Hemmig AK, Gozzoli D, Werlen L, Ewald H, Aschwanden M, Blockmans D, Brouwer E, Buchanan RRC, Camellino D, Campochiaro C, Cimmino MA, Corominas H, Gloy V, Henckaerts L, Kyburz D, Moya-Alvarado P, Owen CE, Stegert M, Tomelleri A, et al. (2022). Subclinical giant cell arteritis in new onset polymyalgia rheumatica A systematic review and meta-analysis of individual patient data. Seminars in Arthritis and Rheumatism, 55, 152017. https://doi.org/10.1016/j.semarthrit.2022.152017

Hoyler, Thomas, Bannert, Bettina, André, Cédric, Beck, Damian, Boulay, Thomas, Buffet, David, Caesar, Nadja, Calzascia, Thomas, Dawson, Janet, Kyburz, Diego, Hennze, Robert, Huppertz, Christine, Littlewood-Evans, Amanda, Loetscher, Pius, Mertz, Kirsten D., Niwa, Satoru, Robert, Gautier, Rush, James S., Ruzzante, Giulia, et al. (2022). Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants. JCI Insight, 7(13). https://doi.org/10.1172/jci.insight.149825

Du Fay De Lavallaz, Jeanne, Prepoudis, Alexandra, Wendebourg, Maria Janina, Kesenheimer, Eva, Kyburz, Diego, Daikeler, Thomas, Haaf, Philip, Wanschitz, Julia, Löscher, Wolfgang N., Schreiner, Bettina, Katan, Mira, Jung, Hans H., Maurer, Britta, Hammerer-Lercher, Angelika, Mayr, Agnes, Gualandro, Danielle M., Acket, Annemarie, Puelacher, Christian, Boeddinghaus, Jasper, et al. (2022). Skeletal Muscle Disorders: A Noncardiac Source of Cardiac Troponin T. Circulation, 145(24), 1764–1779. https://doi.org/10.1161/circulationaha.121.058489

Van Hoovels L, Studholme L, Vander Cruyssen B, Sieghart D, Bonroy C, Nagy E, Pullerits R, Čučnik S, Dahle C, Heijnen I, Bernasconi L, Benkhadra F, Bogaert L, Van Den Bremt S, Van Liedekerke A, Vanheule G, Robbrecht J, Wirth C, Müller R, et al. (2022). Standardisation of ACPA tests: evaluation of a new candidate reference preparation. Annals of the Rheumatic Diseases, 81(10), 1379–1384. https://doi.org/10.1136/annrheumdis-2021-221849

Van Hoovels L, Vander Cruyssen B, Sieghart D, Bonroy C, Nagy E, Pullerits R, Čučnik S, Dahle C, Heijnen I, Bernasconi L, Benkhadra F, Bogaert L, Van Den Bremt S, Van Liedekerke A, Vanheule G, Robbrecht J, Studholme L, Wirth C, Müller R, et al. (2022). Multicentre study to improve clinical interpretation of rheumatoid factor and anti-citrullinated protein/peptide antibodies test results. RMD Open, 8(1). https://doi.org/10.1136/rmdopen-2021-002099

Ciurea A, Kissling S, Bürki K, Baraliakos X, de Hooge M, Hebeisen M, Papagiannoulis E, Exer P, Bräm R, Nissen MJ, Möller B, Kyburz D, Andor M, Distler O, Scherer A, & Micheroli R. (2022). Current differentiation between radiographic and non-radiographic axial spondyloarthritis is of limited benefit for prediction of important clinical outcomes: Data from a large, prospective, observational cohort. RMD Open, 8(1). https://doi.org/10.1136/rmdopen-2021-002067

Kyburz, D. (2022). The painful joint Das schmerzhafte Gelenk. Therapeutische Umschau, 80(1). https://doi.org/10.1024/0040-5930/a001399

Arnold S., Jaeger V.K., Scherer A., Ciurea A, Walker U.A., & Kyburz D. (2022). Discontinuation of biologic DMARDs in a real-world population of patients with rheumatoid arthritis in remission: outcome and risk factors. Rheumatology (United Kingdom), 61(1), 131–138. https://doi.org/10.1093/rheumatology/keab343

Lehmann, Julia, & Kyburz, Diego. (2022). Rheumatoid Arthritis. Therapeutische Umschau, 80, 27–33. https://doi.org/10.1024/0040-5930/a001403

Giaglis S, Daoudlarian D, Voll RE, Kyburz D, Venhoff N, & Walker UA. (2021). Circulating mitochondrial DNA copy numbers represent a sensitive marker for diagnosis and monitoring of disease activity in systemic lupus erythematosus. RMD Open, 7(3). https://doi.org/10.1136/rmdopen-2021-002010

Frei N, Caobelli F, & Kyburz D. (2021). Bilateral proximal hamstring muscle avulsion after treatment with immune checkpoint inhibitors and corticosteroids. Swiss Medical Weekly, 151(35). https://doi.org/10.4414/smw.2021.w30011

Gilbert BTP, Lamacchia C, Mongin D, Lauper K, Trunk E, Studer O, Courvoisier DS, Rubbert-Roth A, Kyburz D, Moeller B, & Finckh A. (2021). Cohort profile: SCREEN-RA: design, methods and perspectives of a Swiss cohort study of first-degree relatives of patients with rheumatoid arthritis. BMJ Open, 11(7), e048409. https://doi.org/10.1136/bmjopen-2020-048409

Ciurea A, Papagiannoulis E, Bürki K, von Loga I, Micheroli R, Möller B, Rubbert-Roth A, Andor M, Bräm R, Müller A, Dan D, Kyburz D, Distler O, Scherer A, & Finckh A. (2021). Impact of the COVID-19 pandemic on the disease course of patients with inflammatory rheumatic diseases: results from the Swiss Clinical Quality Management cohort. Annals of the Rheumatic Diseases, 80(2), 238–241. https://doi.org/10.1136/annrheumdis-2020-218705

Burkard T, Williams RD, Vallejo-Yagüe E, Hügle T, Finckh A, Kyburz D, & Burden AM. (2021). Prediction of sustained biologic and targeted synthetic DMARD-free remission in rheumatoid arthritis patients. Rheumatology Advances in Practice, 5(3), rkab087. https://doi.org/10.1093/rap/rkab087

Tamborrini G, Kyburz D, & Studler U. (2021). [CME Rheumatology 24: DISH of the Hand and Undifferentiated Polyarthritis]. Praxis, 110(14), 778–784. https://doi.org/10.1024/1661-8157/a003767

Tamborrini G, Kyburz D, & Studler U. (2021). [CME Rheumatology 24/Answers: DISH of the Hand and Undifferentiated Polyarthritis]. Praxis, 110(16), 958–960. https://doi.org/10.1024/1661-8157/a003768

Khan, A.W., Deiseroth, A., Hussain, S., Tiaden, A., & Kyburz, D. (2020). Erratum: Exercise-induced improvement of microvascular phenotype and reprogramming of p66ShcDNA methylation (European Heart Journal (2019) 40 (3948-3949) DOI: 10.1093/eurheartj/ehz830). European Heart Journal, 41(46). https://doi.org/10.1093/eurheartj/ehaa009

Fallet B, Kyburz D, & Walker U.A. (2020). Mild Course of COVID-19 and Spontaneous Virus Clearance in a Patient With Depleted Peripheral Blood B Cells Due to Rituximab Treatment. Arthritis and Rheumatology, 72(9), 1581–1582. https://doi.org/10.1002/art.41380

Micheroli R, Tellenbach C, Scherer A, Bürki K, Niederman K, Nissen MJ, Zufferey P, Exer P, Möller B, Kyburz D, & Ciurea A. (2020). Effectiveness of secukinumab versus an alternative TNF inhibitor in patients with axial spondyloarthritis previously exposed to TNF inhibitors in the Swiss Clinical Quality Management cohort. Annals of the Rheumatic Diseases, 79(9), 1203–1209. https://doi.org/10.1136/annrheumdis-2019-215934

Finckh A, Tellenbach C, Herzog L, Scherer A, Moeller B, Ciurea A, von Muehlenen I, Gabay C, Kyburz D, Brulhart L, Müller R, Hasler P, Zufferey P, & physicians and patients of the SCQM. (2020). Comparative effectiveness of antitumour necrosis factor agents, biologics with an alternative mode of action and tofacitinib in an observational cohort of patients with rheumatoid arthritis in Switzerland. RMD Open, 6(1). https://doi.org/10.1136/rmdopen-2020-001174

Fisher B.A., Szanto A., Ng W.-F., Bombardieri M., Posch M.G., Papas A.S., Farag A.M., Daikeler T., Bannert B., Kyburz D., Kivitz A.J., Carsons S.E., Isenberg D.A., Barone F., Bowman S.J., Espie P., Floch D., Dupuy C., Ren X., et al. (2020). Assessment of the anti-CD40 antibody iscalimab in patients with primary Sjögren’s syndrome: a multicentre, randomised, double-blind, placebo-controlled, proof-of-concept study. The Lancet Rheumatology, 2(3), e142–e152. https://doi.org/10.1016/s2665-9913(19)30135-3

Fasler DA, Ingrisch M, Nanz D, Weckbach S, Kyburz D, Fischer DR, Guggenberger R, & Andreisek G. (2020). Rheumatoid cervical pannus: feasibility of volume and perfusion quantification using dynamic contrast enhanced time resolved MRI. Acta Radiologica, 61(2), 227–235. https://doi.org/10.1177/0284185119854200

Quero, Lilian, Tiaden, André N., Hanser, Edveena, Roux, Julien, Laski, Artur, Hall, Jonathan, & Kyburz, Diego. (2020). miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.03087

Quero, Lilian, Tiaden, André N., Hanser, Edveena, Roux, Julien, Laski, Artur, Hall, Jonathan, & Kyburz, Diego. (2020). miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation [Journal-article]. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.03087

Streese, Lukas, Khan, Abdul Waheed, Deiseroth, Arne, Hussain, Shafaat, Suades, Rosa, Tiaden, Andre, Kyburz, Diego, Cosentino, Francesco, & Hanssen, Henner. (2020). High-intensity interval training modulates retinal microvascular phenotype and DNA methylation of p66Shc gene: a randomized controlled trial (EXAMIN AGE). European Heart Journal, 41(15), 1514–1519. https://doi.org/10.1093/eurheartj/ehz196

Streese, Lukas, Khan, Abdul W., Deiseroth, Arne, Hussain, Shafaat, Suades, Rosa, Tiaden, Andre, Kyburz, Diego, Hanssen, Henner, & Cosentino, Francesco. (2020). Physical activity may drive healthy microvascular ageing via downregulation of p66 Shc. European Journal of Preventive Cardiology, 27(2), 168–176. https://doi.org/10.1177/2047487319880367

Ankli B, Berger CT, Haeni N, Kyburz D, Hügle T, So AK, & Daikeler T. (2019). The target uric acid level in multimorbid patients with gout is difficult to achieve: Data from a longitudinal Swiss single-centre cohort. Swiss Medical Weekly, 149(35-36), w20121. https://doi.org/10.4414/smw.2019.20121

Hargreaves P, Daoudlarian D, Theron M, Kolb FA, Manchester Young M, Reis B, Tiaden A, Bannert B, Kyburz D, & Manigold T. (2019). Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome. Arthritis Research & Therapy, 21(1), 175. https://doi.org/10.1186/s13075-019-1955-2

Scholz GA, Leichtle AB, Scherer A, Arndt U, Fiedler M, Aeberli D, Finckh A, Gabay C, Kyburz D, Villiger PM, & Möller B. (2019). The links of hepcidin and erythropoietin in the interplay of inflammation and iron deficiency in a large observational study of rheumatoid arthritis. British Journal of Haematology, 186(1), 101–112. https://doi.org/10.1111/bjh.15895

Bühler, Silja, Jaeger, Veronika Katharina, Adler, Sabine, Bannert, Bettina, Brümmerhoff, Carolin, Ciurea, Adrian, Distler, Oliver, Franz, Juliane, Gabay, Cem, Hagenbuch, Niels, Herzog, Christian, Hasler, Paul, Kling, Kerstin, Kyburz, Diego, Müller, Rüdiger, Nissen, Michael John, Siegrist, Claire-Anne, Villiger, Peter Matthias, Walker, Ulrich A., & Hatz, Christoph. (2019). Safety and immunogenicity of tetanus/diphtheria vaccination in patients with rheumatic diseases-a prospective multi-centre cohort study. Rheumatology, 58(9), 1585–1596. https://doi.org/10.1093/rheumatology/kez045

Lechtenboehmer CA, Jaeger VK, Kyburz D, Walker UA, & Hügle T. (2019). Brief Report: Influence of Disease Activity in Rheumatoid Arthritis on Radiographic Progression of Concomitant Interphalangeal Joint Osteoarthritis. Arthritis and Rheumatology, 71(1), 43–49. https://doi.org/10.1002/art.40684

Buttgereit F, DGRh, Brabant T, DGG, Dinges H, DGOOC, Hiemer I, Rheuma-Liga, Kaplani M, DGIM, Kiltz U, Kyburz D, SGR, Reißhauer A, DGPMR, Schneider M, Weseloh C, Dejaco C, & ÖGR. (2018). [S3 guidelines on treatment of polymyalgia rheumatica : Evidence-based guidelines of the German Society of Rheumatology (DGRh), the Austrian Society of Rheumatology and Rehabilitation (ÖGR) and the Swiss Society of Rheumatology (SGT) and participating medical scientific specialist societies and other organizations]. Zeitschrift fur Rheumatologie, 77(5), 429–441. https://doi.org/10.1007/s00393-018-0476-8

Deiseroth A, Marcin T, Berger C, Infanger D, Schäfer J, Bannert B, Schmidt-Trucksäss A, Voll RE, Kyburz D, & Hanssen H. (2018). Retinal vessel diameters and physical activity in patients with mild to moderate rheumatic disease without cardiovascular comorbidities. Frontiers in Psychiatry, 9(MAR), 176. https://doi.org/10.3389/fphys.2018.00176

Ankli B, Kyburz D, Hirschmann A, Hügle T, Manigold T, Berger CT, & Daikeler T. (2018). Calcium pyrophosphate deposition disease: a frequent finding in patients with long-standing erosive gout. Scandinavian Journal of Rheumatology, 47(2), 127–130. https://doi.org/10.1080/03009742.2017.1332239

Quero L, Hanser E, Manigold T, Tiaden AN, & Kyburz D. (2017). TLR2 stimulation impairs anti-inflammatory activity of M2-like macrophages, generating a chimeric M1/M2 phenotype. Arthritis Research and Therapy, 19(1), 245. https://doi.org/10.1186/s13075-017-1447-1

Quero, Lilian, Hanser, Edveena, Manigold, Tobias, Tiaden, André N., & Kyburz, Diego. (2017). TLR2 stimulation impairs anti-inflammatory activity of M2-like macrophages, generating a chimeric M1/M2 phenotype [Journal-article]. Arthritis Research and Therapy, 19(1). https://doi.org/10.1186/s13075-017-1447-1

Tamborrini G, & Kyburz D. (2017). [CME Rheumatology 13/Solution: Shoulder Pain, Muscle Weakness and Skin Rash]. Praxis, 106(24), 1360. https://doi.org/10.1024/1661-8157/a002858

Tamborrini G, & Kyburz D. (2017). [CME Rheumatology 13: Shoulder Pain, Muscle Weakness and Skin Rash]. Praxis, 106(23), 1271–1272. https://doi.org/10.1024/1661-8157/a002857

Walker UA, Mueller RB, Jaeger VK, Theiler R, Forster A, Dufner P, Ganz F, & Kyburz D. (2017). Disease activity dynamics in rheumatoid arthritis: Patients’ self-assessment of disease activity via WebApp. Rheumatology (United Kingdom), 56(10), 1707–1712. https://doi.org/10.1093/rheumatology/kex229

Alpizar-Rodriguez D, Mueller RB, Möller B, Dudler J, Ciurea A, Zufferey P, Kyburz D, Walker UA, von Mühlenen I, Roux-Lombard P, Mahler M, Lamacchia C, Courvoisier DS, Gabay C, & Finckh A. (2017). Female hormonal factors and the development of anti-citrullinated protein antibodies in women at risk of rheumatoid arthritis. Rheumatology (United Kingdom), 56(9), 1579–1585. https://doi.org/10.1093/rheumatology/kex239

Alpizar-Rodriguez D, Brulhart L, Mueller RB, Möller B, Dudler J, Ciurea A, Walker UA, Von Mühlenen I, Kyburz D, Zufferey P, Mahler M, Bas S, Gascon D, Lamacchia C, Roux-Lombard P, Lauper K, Nissen MJ, Courvoisier DS, Gabay C, & Finckh A. (2017). The prevalence of anticitrullinated protein antibodies increases with age in healthy individuals at risk for rheumatoid arthritis. Clinical Rheumatology, 36(3), 677–682. https://doi.org/10.1007/s10067-017-3547-3

Rizzi M, Lorenzetti R, Fischer K, Staniek J, Janowska I, Troilo A, Strohmeier V, Erlacher M, Kunze M, Bannert B, Kyburz D, Voll RE, Venhoff N, & Thiel J. (2017). Impact of tofacitinib treatment on human B-cells in vitro and in vivo. Journal of Autoimmunity, 77, 55–66. https://doi.org/10.1016/j.jaut.2016.10.005

Imfeld, Stefan, Rottenburger, Christoph, Schegk, Elke, Aschwanden, Markus, Juengling, Freimut, Staub, Daniel, Recher, Mike, Kyburz, Diego, Berger, Christoph T., & Daikeler, Thomas. (2017). [18F]FDG positron emission tomography in patients presenting with suspicion of giant cell arteritis-lessons from a vasculitis clinic. Eur Heart J Cardiovasc Imaging, 19(8), 933–940. https://doi.org/10.1093/ehjci/jex259

Manigold,Tobias, Hirschmann,Anna, Kybur,Diego, Daikeler,Thomas, Ankli,Barbara, & Büttner,Franz. (2016). Gouty Arthritis of the Atlantodental Joint. Arthritis and Rheumatology, 68(6), 1539. https://doi.org/10.1002/art.39645

Franzen, Daniel, Ciurea, Adrian, Bratton, Daniel J., Clarenbach, Christian F., Latshang, Tsogyal D., Russi, Erich W., Kyburz, Diego, & Kohler, Malcolm. (2016). Effect of rituximab on pulmonary function in patients with rheumatoid arthritis. Pulmonary Pharmacology & Therapeutics, 37, 9–24. https://doi.org/10.1016/j.pupt.2016.02.002

Boehncke, Wolf-Henning, Anliker, Mark David, Conrad, Curdin, Dudler, Jean, Hasler, Fritz, Hasler, Paul, Hausermann, Peter, Kyburz, Diego, Laffitte, Emmanuel, Michel, Beat A., Moller, Burkhard, Navarini, Alexander A., Villiger, Peter M., Yawalkar, Nikhil, & Gabay, Cem. (2015). The dermatologists’ role in managing psoriatic arthritis: results of a Swiss Delphi exercise intended to improve collaboration with rheumatologists. Dermatology, 230(1), 75–81. https://doi.org/10.1159/000367688

Bühler, Silja, Eperon, Gilles, Ribi, Camillo, Kyburz, Diego, van Gompel, Fons, Visser, Leo G., Siegrist, Claire-Anne, & Hatz, Christoph. (2015). Vaccination recommendations for adult patients with autoimmune inflammatory rheumatic diseases. Swiss Medical Weekly, 145, w14159. https://doi.org/10.4414/smw.2015.14159

Hruska-Plochan, Marian, Li, Bei, Kyburz, Diego, Krutzfeld, Jan, Landmesser, Ulf, Aguzzi, Adriano, & Polymenidou, Magdalini. (2015). New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases. Swiss Medical Weekly, 145, w14192. https://doi.org/10.4414/smw.2015.14192

Micheroli, Raphael, Kyburz, Diego, Ciurea, Adrian, Dubs, Beat, Toniolo, Martin, Bisig, Samuel Pascal, & Tamborrini, Giorgio. (2015). Correlation of findings in clinical and high resolution ultrasonography examinations of the painful shoulder. Journal of Ultrasonography, 15(60), 29–44. https://doi.org/10.15557/jou.2015.0003

Engler A, Niederer F, Klein K, Gay RE, Kyburz D, Camici GG, Gay S, & Ospelt C. (2014). SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts. Journal of Molecular Medicine, 92(7), 757–767. https://doi.org/10.1007/s00109-014-1139-0

Finckh, Axel, Mc Carthy, Geraldine M., Madigan, Anne, Van Linthoudt, Daniel, Weber, Marcel, Neto, David, Rappoport, Georges, Blumhardt, Sandra, Kyburz, Diego, & Guerne, Pierre-Andre. (2014). Methotrexate in chronic-recurrent calcium pyrophosphate deposition disease: No significant effect in a randomized crossover trial. Arthritis Research and Therapy, 16(1). https://doi.org/10.1186/s13075-014-0458-4

Gabay, Cem, Hasler, Paul, Kyburz, Diego, Soukas, Alexander, Villiger, Peter M., von Kempis, Johannes, & Walker, Ulrich A. (2014). Biological agents in monotherapy for the treatment of rheumatoid arthritis. Swiss Medical Weekly, 144, w13950. https://doi.org/10.4414/smw.2014.13950

Kyburz, Diego, Karouzakis, Emmanuel, & Ospelt, Caroline. (2014). Epigenetic changes: the missing link. Best Pract Res Clin Rheumatol, 28(4), 87–577. https://doi.org/10.1016/j.berh.2014.10.014

Zufferey P, Tamborrini G, Gabay C, Krebs A, Kyburz D, Michel B, Moser U, Villiger PM, So A, & Ziswiler HR. (2013). Recommendations for the use of ultrasound in rheumatoid arthritis: Literature review and SONAR score experience. Swiss Medical Weekly, 143, w13861. https://doi.org/10.4414/smw.2013.13861

Scherrer CB, Mannion AF, Kyburz D, Vogt M, & Kramers-de Quervain IA. (2013). Infection risk after orthopedic surgery in patients with inflammatory rheumatic diseases treated with immunosuppressive drugs. Arthritis Care and Research, 65(12), 2032–2040. https://doi.org/10.1002/acr.22077

Présumey J, Courties G, Louis-Plence P, Escriou V, Scherman D, Pers YM, Yssel H, Pène J, Kyburz D, Gay S, Jorgensen C, & Apparailly F. (2013). Nicotinamide phosphoribosyltransferase/visfatin expression by inflammatory monocytes mediates arthritis pathogenesis. Annals of the Rheumatic Diseases, 72(10), 1717–1724. https://doi.org/10.1136/annrheumdis-2012-202403

Schöni M, Drerup S, Angst F, Kyburz D, Simmen BR, & Goldhahn J. (2013). Long-term survival of GSB III elbow prostheses and risk factors for revisions. Archives of Orthopaedic and Trauma Surgery, 133(10), 1415–1424. https://doi.org/10.1007/s00402-013-1815-5

Kyburz, Diego, & Finckh, Axel. (2013). The importance of early treatment for the prognosis of rheumatoid arthritis. Swiss Medical Weekly, 143. https://doi.org/10.4414/smw.2013.13865

Niederer, F., Scherer, A., Kyburz, D., Gay, R. E., Gay, S., Michel, B. A., & Ciurea, A. (2013). Serum levels of BAFF in patients with ankylosing spondylitis and treated with anti-TNF Taux sériques de BAFF chez les patients atteints de spondylarthrite ankylosante et traités par anti-TNF. Revue Du Rhumatisme (Edition Francaise), 80(4), 417–419. https://doi.org/10.1016/j.rhum.2013.01.009

Niederer F, Scherer A, Kyburz D, Gay RE, Gay S, Michel BA, & Ciurea A. (2013). BAFF levels in patients with ankylosing spondylitis and response to anti-tumor necrosis factor treatment. Joint Bone Spine, 80(4), 433–434. https://doi.org/10.1016/j.jbspin.2012.10.004

Kyburz, D., & Niederer, F. (2013). The role of sirtuins in arthritis. In Studies on Arthritis and Joint Disorders (pp. 333–348). Springer New York. https://doi.org/10.1007/978-1-4614-6166-1_18

Finckh,Axel, Möller,Burkhard, Dudler,Jean, Walker,Ulrich A, Walker,Ulrich A, Kyburz,Diego, Gabay,Cem, physicians of the Swiss Clinical Quality Management for Rheumatoid Arthritis, & physicians of SCQM-RA. (2012). Evolution of radiographic joint damage in rituximab-treated versus TNF-treated rheumatoid arthritis cases with inadequate response to TNF antagonists. Annals of the Rheumatic Diseases, 71(10), 1680–1685. https://doi.org/10.1136/annrheumdis-2011-201016

Meier FM, Frommer KW, Peters MA, Brentano F, Lefèvre S, Schröder D, Kyburz D, Steinmeyer J, Rehart S, Gay S, Müller-Ladner U, & Neumann E. (2012). Visfatin/pre-B-cell colony-enhancing factor (PBEF), a proinflammatory and cell motility-changing factor in rheumatoid arthritis. Journal of Biological Chemistry, 287(34), 28378–28385. https://doi.org/10.1074/jbc.m111.312884

Niederer F, Trenkmann M, Ospelt C, Karouzakis E, Neidhart M, Stanczyk J, Kolling C, Gay RE, Detmar M, Gay S, Jüngel A, & Kyburz D. (2012). Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. Arthritis and Rheumatism, 64(6), 1771–1779. https://doi.org/10.1002/art.34334

von Kempis J, Dudler J, Hasler P, Kyburz D., Tyndall A, Zufferey P, & Villiger PM. (2012). Use of abatacept in rheumatoid arthritis: Recommendations based on current evidence. Swiss Medical Weekly, 142(MAY). https://doi.org/10.4414/smw.2012.13581

Bombardieri M, Kam NW, Brentano F, Choi K, Filer A, Kyburz D, McInnes IB, Gay S, Buckley C, & Pitzalis C. (2011). A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells. Annals of the Rheumatic Diseases, 70(10), 1857–1865. https://doi.org/10.1136/ard.2011.150219

Niederer F, Ospelt C, Brentano F, Hottiger MO, Gay RE, Gay S, Detmar M, & Kyburz D. (2011). SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Annals of the Rheumatic Diseases, 70(10), 1866–1873. https://doi.org/10.1136/ard.2010.148957

Raza,Karim, Stack,Rebecca, Kumar,Kanta, Filer,Andrew, Detert,Jacqueline, Bastian,Hans, Burmester,Gerd R, Sidiropoulos,Prodromos, Kteniadaki,Eleni, Repa,Argyro, Saxne,Tore, Turesson,Carl, Mann,Herman, Vencovsky,Jiri, Catrina,Anca, Chatzidionysiou,Aikaterini, Hensvold,Aase, Rantapää-Dahlqvist,Solbritt, Binder,Alexa, et al. (2011). Delays in assessment of patients with rheumatoid arthritis: Variations across Europe. Annals of the Rheumatic Diseases, 70(10), 1822–1825. https://doi.org/10.1136/ard.2011.151902

Micheroli R, Kyburz D, Ciurea A, & Tamborrini G. (2011). [The rheumatic hand - diagnostics in practice]. Praxis, 100(18), 106–1097. https://doi.org/10.1024/1661-8157/a000655

Kyburz D, & Corr M. (2011). Th17 cells generated in the absence of TGF-β induce experimental allergic encephalitis upon adoptive transfer. Expert Review of Clinical Immunology, 7(3), 283–285. https://doi.org/10.1586/eci.11.7

Stanczyk J, Ospelt C, Karouzakis E, Filer A, Raza K, Kolling C, Gay R, Buckley CD, Tak PP, Gay S, & Kyburz D. (2011). Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis and Rheumatism, 63(2), 373–381. https://doi.org/10.1002/art.30115

Duroux-Richard I, Presumey J, Courties G, Gay S, Gordeladze J, Jorgensen C, Kyburz D, & Apparailly F. (2011). MicroRNAs as new player in rheumatoid arthritis. Joint Bone Spine, 78(1), 17–22. https://doi.org/10.1016/j.jbspin.2010.06.003

Duroux-Richard, I., Presumey, J., Courties, G., Gay, S., Gordeladze, J., Jorgensen, C., Kyburz, D., & Apparailly, F. (2011). MicroRNAs: New players in rheumatoid arthritis Les microARN: De nouveaux acteurs de la polyarthrite rhumatoïde. Revue Du Rhumatisme (Edition Francaise), 78(2), 109–115. https://doi.org/10.1016/j.rhum.2010.06.004

Kyburz D, Gabay C, Michel BA, Finckh A, & physicians of SCQM-RA. (2011). The long-term impact of early treatment of rheumatoid arthritis on radiographic progression: a population-based cohort study. Rheumatology (Oxford, England), 50(6), 1106–1110. https://doi.org/10.1093/rheumatology/keq424

Finckh, A., Dudler, J., Wermelinger, F., Ciurea, A., Kyburz, D., Gabay, C., & Bas, S. (2010). Effect of anti-infliximab antibodies and the residual concentrations of infliximab on the development of acquired resistance to infliximab among patients with rheumatoid arthritis Influence des anticorps anti-infliximab et des concentrations résiduelles d’infliximab sur l’apparition d’une résistance acquise à l’infliximab chez les patients atteints de polyarthrite rhumatoïde. Revue Du Rhumatisme (Edition Francaise), 77(6), 602–608. https://doi.org/10.1016/j.rhum.2010.07.007

Strobel,Klaus, Fischer,Dorothee R, Tamborrini,Giorgio, Kyburz,Diego, Stumpe,Katrin D M, Hesselmann,Rolf G X, Johayem,A, von Schulthess,Gustav K, Michel,Beat A, & Ciurea,Adrian. (2010). 18F-Fluoride PET/CT for detection of sacroiliitis in ankylosing spondylitis. European Journal of Nuclear Medicine and Molecular Imaging, 37(9), 1760–1765. https://doi.org/10.1007/s00259-010-1464-7

Finckh A, Dudler J, Wermelinger F, Ciurea A, Kyburz D, Gabay C, Bas S, & physicians of SCQM. (2010). Influence of anti-infliximab antibodies and residual infliximab concentrations on the occurrence of acquired drug resistance to infliximab in rheumatoid arthritis patients. Joint Bone Spine, 77(4), 313–318. https://doi.org/10.1016/j.jbspin.2010.02.021