Dr. Thomas Braun

Rima, Luca, Berchtold, Christian, Arnold, Stefan, Fränkl, Andri, Sütterlin, Rosmarie, Dernick, Gregor, Schlotterbeck, Götz, & Braun, Thomas. (2024). Single and few cell analysis for correlative light microscopy, metabolomics, and targeted proteomics [Journal-article]. Lab on a Chip, 24(18), 4321–4332 . https://doi.org/10.1039/d4lc00269e

Rima, Luca, Zimmermann, Michael, Fränkl, Andri, Clairfeuille, Thomas, Lauer, Matthias, Engel, Andreas, Engel, Hans-Andreas, & Braun, Thomas. (2022). cryoWriter: a blotting free cryo-EM preparation system with a climate jet and cover-slip injector. Faraday Discussions, 240, 55–66. https://doi.org/10.1039/d2fd00066k

Mortelmans, Thomas, Kazazis, Dimitrios, Guzenko, Vitaliy A., Padeste, Celestino, Braun, Thomas, Stahlberg, Henning, Li, Xiaodan, & Ekinci, Yasin. (2020). Grayscale e-beam lithography: Effects of a delayed development for well-controlled 3D patterning. Microelectronic Engineering, 225, 111272. https://doi.org/10.1016/j.mee.2020.111272

Oliva, Paolo, Bircher, Benjamin Andreas, Schoenenberger, Cora-Ann, & Braun, Thomas. (2019). Array based real-time measurement of fluid viscosities and mass-densities to monitor biological filament formation. Lab on a Chip, 19(7), 1305–1314. https://doi.org/10.1039/c8lc01343h

Schmidli, Claudio, Albiez, Stefan, Rima, Luca, Righetto, Ricardo, Mohammed, Inayatulla, Oliva, Paolo, Kovacik, Lubomir, Stahlberg, Henning, & Braun, Thomas. (2019). Microfluidic protein isolation and sample preparation for high-resolution cryo-EM. Proceedings of the National Academy of Sciences of the United States of America, 116(30), 15007–15012. https://doi.org/10.1073/pnas.1907214116

Syntychaki, Anastasia, Rima, Luca, Schmidli, Claudio, Stohler, Thomas, Bieri, Andrej, Sütterlin, Rosmarie, Stahlberg, Henning, Castaño-Díez, Daniel, & Braun, Thomas. (2019). “Differential Visual Proteomics”: Enabling the Proteome-Wide Comparison of Protein Structures of Single-Cells. Journal of Proteome Research, 18(9), 3521–3531. https://doi.org/10.1021/acs.jproteome.9b00447

Arnold, Stefan A., Müller, Shirley A., Schmidli, Claudio, Syntychaki, Anastasia, Rima, Luca, Chami, Mohamed, Stahlberg, Henning, Goldie, Kenneth N., & Braun, Thomas. (2018). Miniaturizing EM Sample Preparation: Opportunities, Challenges, and “Visual Proteomics”. Proteomics, 18(5-6), 1700176. https://doi.org/10.1002/pmic.201700176

Schmidli, Claudio, Rima, Luca, Arnold, Stefan A., Stohler, Thomas, Syntychaki, Anastasia, Bieri, Andrej, Albiez, Stefan, Goldie, Kenneth N., Chami, Mohamed, Stahlberg, Henning, & Braun, Thomas. (2018). Miniaturized Sample Preparation for Transmission Electron Microscopy. Journal of Visualized Experiments, 137, e57310. https://doi.org/10.3791/57310

Arnold, Stefan A., Albiez, Stefan, Bieri, Andrej, Syntychaki, Anastasia, Adaixo, Ricardo, McLeod, Robert A., Goldie, Kenneth N., Stahlberg, Henning, & Braun, Thomas. (2017). Blotting-free and lossless cryo-electron microscopy grid preparation from nanoliter-sized protein samples and single-cell extracts. Journal of Structural Biology, 197(3), 220–226. https://doi.org/10.1016/j.jsb.2016.11.002

Opara, Nadia, Martiel, Isabelle, Arnold, Stefan A., Braun, Thomas, Stahlberg, Henning, Makita, Mikako, David, Christian, & Padeste, Celestino. (2017). Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers. Journal of Applied Crystallography, 50(3), 909–918. https://doi.org/10.1107/s1600576717005799

Arnold, Stefan A., Albiez, Stefan, Opara, Nadia, Chami, Mohamed, Schmidli, Claudio, Bieri, Andrej, Padeste, Celestino, Stahlberg, Henning, & Braun, Thomas. (2016). Total Sample Conditioning and Preparation of Nanoliter Volumes for Electron Microscopy. ACS Nano, 10(5), 4981–4988. https://doi.org/10.1021/acsnano.6b01328

Bircher, Benjamin A., Krenger, Roger, & Braun, Thomas. (2016). Automated high-throughput viscosity and density sensor using nanomechanical resonators. Sensors and Actuators B: Chemical, 223, 784–790. https://doi.org/10.1016/j.snb.2015.09.084

Escobedo, C., Bürgel, S. C., Kemmerling, S., Sauter, N., Braun, T., & Hierlemann, A. (2015). On-chip lysis of mammalian cells through a handheld corona device. Lab on a Chip, 15(14), 2990–2997. https://doi.org/10.1039/c5lc00552c

Bircher, Benjamin A., & Braun, Thomas. (2014, January 1). Microcantilever vibrations to characterize fluids with high temporal resolution.

Bircher, Benjamin A., Krenger, Roger, & Braun, Thomas. (2014). Influence of squeeze-film damping on higher-mode microcantilever vibrations in liquid. EPJ Techniques and Instrumentation, 1, 10. https://doi.org/10.1140/epjti/s40485-014-0010-6

Giss, Dominic, Kemmerling, Simon, Dandey, Venkata, Stahlberg, Henning, & Braun, Thomas. (2014). Exploring the interactome : microfluidic isolation of proteins and interacting partners for quantitative analysis by electron microscopy. Analytical Chemistry, 86(10), 4680–4687. https://doi.org/10.1021/ac4027803

Ramakrishnan, Chandrasekhar, Bieri, Andrej, Sauter, Nora, Roizard, Sophie, Ringler, Philippe, Müller, Shirley A., Goldie, Kenneth N., Enimanev, Kaloyan, Stahlberg, Henning, Rinn, Bernd, & Braun, Thomas. (2014). openBEB: open biological experiment browser for correlative measurements. BMC Bioinformatics, 15, 84. https://doi.org/10.1186/1471-2105-15-84

Bircher, Benjamin A., Dümpelmann, Luc, Renggli, Kasper, Lang, Hans Peter, Gerber, Christoph, Bruns, Nico, & Braun, Thomas. (2013). Real-Time Viscosity and Mass Density Sensors Requiring Microliter Sample Volume Based on Nanomechanical Resonators. Analytical Chemistry, 85(18), 8676–8683. https://doi.org/10.1021/ac4014918

Bircher, Benjamin Andreas, Duempelmann, Luc, Lang, Hans Peter, Gerber, Christoph, & Braun, Thomas. (2013). Photothermal excitation of microcantilevers in liquid: effect of the excitation laser position on temperature and vibrational amplitude. Micro and Nano Letters, 8(11), 770–774. https://doi.org/10.1049/mnl.2013.0352

Kemmerling, Simon, Arnold, Stefan A., Bircher, Benjamin A., Sauter, Nora, Escobedo, Carlos, Dernick, Gregor, Hierlemann, Andreas, Stahlberg, Henning, & Braun, Thomas. (2013). Single-cell lysis for visual analysis by electron microscopy. Journal of Structural Biology, 183(3), 467–473. https://doi.org/10.1016/j.jsb.2013.06.012

Kemmerling, Simon, Ziegler, Jörg, Schweighauser, Gabriel, Arnold, Stefan A., Giss, Dominic, Müller, Shirley A., Ringler, Philippe, Goldie, Kenneth N., Goedecke, Nils, Hierlemann, Andreas, Stahlberg, Henning, Engel, Andreas, & Braun, Thomas. (2012). Connecting μ-fluidics to electron microscopy. Journal of Structural Biology, 177(1), 128–134. https://doi.org/10.1016/j.jsb.2011.11.001

Weidmann, Simon, Kemmerling, Simon, Mädler, Stefanie, Stahlberg, Henning, Braun, Thomas, & Zenobi, Renato. (2012). Ionic liquids as matrices in microfluidic sample deposition for high-mass matrix-assisted laser desorption/ionization mass spectrometry. European Journal of Mass Spectrometry, 18(3), 279–286. https://doi.org/10.1255/ejms.1182

Backmann, Natalija, Kappeler, Natascha, Braun, Thomas, Huber, François, Lang, Hans-Peter, Gerber, Christoph, & Lim, Roderick Y. H. (2010). Sensing surface PEGylation with microcantilevers. Beilstein Journal of Nanotechnology, 1, 3–13. https://doi.org/10.3762/bjnano.1.2

Braun, Thomas, & Ghatkesar, Murali Krishna. (2009). Technologies at Hand: Measuring the intrinsic nanomechanics of molecular interactions with microcantilever sensors. European Journal of Nanomedicine, 2(1), 13–15. https://doi.org/10.1515/ejnm.2009.2.1.13

Braun, Thomas, Ghatkesar, Murali Krishna, Backmann, Natalija, Grange, Wilfried, Boulanger, Pascale, Letellier, Lucienne, Lang, Hans-Peter, Bietsch, Alex, Gerber, Christoph, & Hegner, Martin. (2009). Quantitative time-resolved measurement of membrane protein-ligand interactions using microcantilever array sensors. Nature Nanotechnology, 4(3), 179–185. https://doi.org/10.1038/nnano.2008.398

Ghatkesar, Murali Krishna, Braun, Thomas, Barwich, Viola, Ramseyer, Jean-Pierre, Gerber, Christoph, Hegner, Martin, & Lang, Hans Peter. (2008). Resonating modes of vibrating microcantilevers in liquid. Applied Physics Letters, 92(4), 43106. https://doi.org/10.1063/1.2838295

Ghatkesar, Murali Krishna, Lang, Hans-Peter, Gerber, Christoph, Hegner, Martin, & Braun, Thomas. (2008). Comprehensive characterization of molecular interactions based on nanomechanics. PLoS ONE, 3(11), e3610. https://doi.org/10.1371/journal.pone.0003610

Ghatkesar, Murali Krishna, Rakhmatullina, Ekaterina, Lang, Hans-Peter, Gerber, Christoph, Hegner, Martin, & Braun, Thomas. (2008). Multi-parameter microcantilever sensor for comprehensive characterization of Newtonian fluids. Sensors and Actuators B: Chemical, 135(1), 133–138. https://doi.org/10.1016/j.snb.2008.08.012

Braun, T., Ghatkesar, M. K., Barwich, V., Backmann, N., Huber, F., Grange, W., Nugaeva, N., Lang, H. P., Ramseyer, J. P., Gerber, Ch, & Hegner, M. (2007). Digital processing of multi-mode nano-mechanical cantilever data. Journal of Physics: Conference Series, 61. https://doi.org/10.1088/1742-6596/61/1/069

Braun, Thomas, Huber, François, Ghatkesar, Murali Krishna, Backmann, Natalija, Lang, Hans Peter, Gerber, Christoph, & Hegner, Martin. (2007). Processing of kinetic microarray signals. Sensors and Actuators. B, Chemical, 128(1), 75–82. https://doi.org/10.1016/j.snb.2007.05.031

Ghatkesar, Murali Krishna, Barwich, Viola, Braun, Thomas, Ramseyer, Jean-Pierre, Gerber, Christoph, Hegner, Martin, Lang, Hans Peter, Drechsler, Ute, & Despont, Michel. (2007). Higher modes of vibration increase mass sensitivity in nanomechanical microcantilevers. Nanotechnology, 18(44), 445502. https://doi.org/10.1088/0957-4484/18/44/445502

Khuri-Yakub, B. T., Park, K. K., Lee, H. J., Yaralioglu, G. G., Ergun, S., Oralkan, O., Kupnik, M., Quate, C. F., Braun, T., Lang, H. P., Hegner, Martin, Ramseyer, Jean-Pierre, Gerber, Christoph, & Gimzewski, J. (2007, January 1). The capacitive micromachined ultrasonic transducer (CMUT) as a chem/bio sensor. https://doi.org/10.1109/ultsym.2007.127

Park, K. K., Lee, H. J., Yaralioglu, G. G., Ergun, A. S., Oralkan, Ö., Kupnik, M., Quate, C. F., Khuri-Yakub, B. T., Braun, T., Ramseyer, J. -P., Lang, H. P., Hegner, M., Gerber, Ch., & Gimzewski, J. K. (2007). Capacitive micromachined ultrasonic transducers for chemical detection in nitrogen. Applied Physics Letters, 91(9), 94102. https://doi.org/10.1063/1.2776348

Rakhmatullina, Ekaterina, Braun, Thomas, Chami, Mohamed, Malinova, Violeta, & Meier, Wolfgang. (2007). Self-Organization Behavior of Methacrylate-Based Amphiphilic Di- and Triblock Copolymers. Langmuir, 23(24), 12371–12379. https://doi.org/10.1021/la7023132

Rakhmatullina, Ekaterina, Braun, Thomas, Kaufmann, Thomas, Spillmann, Hannes, Malinova, Violeta, & Meier, Wolfgang. (2007). Functionalization of Gold and Silicon Surfaces by Copolymer Brushes Using Surface-Initiated ATRP. Macromolecular Chemistry and Physics, 208(12), 1283–1293. https://doi.org/10.1002/macp.200700119

Braun, Thomas, Backmann, Natalija, Vogtli, Manuel, Bietsch, Alexander, Engel, Andreas, Lang, Hans-Peter, Gerber, Christoph, & Hegner, Martin. (2006). Conformational change of bacteriorhodopsin quantitatively monitored by microcantilever sensors. Biophysical Journal, 90(8), 2970–2977. https://doi.org/10.1529/biophysj.105.072934

Kukulski, Wanda, Schenk, Andreas, Braun, Thomas, Karlsson, Maria, Kjellbom, Peter, Fotiadis, Dimitrios, & Engel, Andreas. (2005). The 5 structure of heterologously expressed plant aquaporin PM28A. FEBS Journal, 272.

Braun, Thomas, & Engel, Andreas. (2005). Two-dimensional electron crystallography. In Encyclopedia of life sciences (pp. 1–7). Wiley. https://doi.org/10.1038/npg.els.0003044

Braun, Thomas, Kaufmann, Thomas C., Rémigy, Hervé-W., & Engel, Andreas. (2005). Two‐dimensional Crystallization of Membrane Proteins. In Ganten, Detlev; Ruckpaul, Klaus (Ed.), Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine: Vol. 2: M - Z (pp. 1936–1942). Springer. https://doi.org/10.1007/3-540-29623-9_5120

Ghatkesar, Murali K., Barwich, V., Braun, T., Bredekamp, A. H., Drechsler, U., Despont, M., Lang, H. P., Hegner, M., & Gerber, C. (2004). Real-time mass sensing by nanomechanical resonators in fluid (Rocha, Daniel; Sarro, Pasqualina M.; Vellekoop, Michiel Johannes, Ed.; Vol. 2). IEEE. https://doi.org/10.1109/icsens.2004.1426357

Stahlberg, Henning, Fotiadis, Dimitrios, Scheuring, Simon, Rémigy, Hervé, Braun, Thomas, Mitsuoka, Kaoru, Fujiyoshi, Yoshinori, & Engel, Andreas. (2001). Two-dimensional crystals : a powerful approach to assess structure, function and dynamics of membrane proteins. FEBS Letters, 504(3), 166–172. https://doi.org/10.1016/s0014-5793(01)02746-6

Braun, Thomas, McIlhinney, R. A. Jeffrey, & Vergères, Guy. (2000). Myristoylation-dependent N-terminal cleavage of the myristoylated alanine-rich C kinase substrate (MARCKS) by cellular extracts. Biochimie, 82(8), 705–715. https://doi.org/10.1016/s0300-9084(00)01154-8

Braun, Thomas, Philippsen, Ansgar, Wirtz, Sabine, Borgnia, Mario J., Agre, Peter, Kühlbrandt, Werner, Engel, Andreas, & Stahlberg, Henning. (2000). The 3.7 projection map of the glycerol facilitator GlpF: A variant of the aquaporin tetramer. EMBO Reports, 1(2), 183–189. https://doi.org/10.1093/embo-reports/kvd022

Stahlberg, Henning, Braun, Thomas, de Groot, Bert, Philippsen, Ansgar, Borgnia, Mario J., Agre, Peter, Kühlbrandt, Werner, & Engel, Andreas. (2000). The 6.9-A structure of GlpF : a basis for homology modeling of the glycerol channel from Escherichia coli. Journal of Structural Biology, 132(2), 133–141. https://doi.org/10.1006/jsbi.2000.4317

Ulrich, Andreas, Schmitz, Arndt A. P., Braun, Thomas, Yuan, Tao, Vogel, Hans J., & Vergères, Guy. (2000). Mapping the interface between calmodulin and MARCKS-related protein by fluorescence spectroscopy. Proceedings of the National Academy of Sciences of the United States of America, 97(10), 5191–5196. https://doi.org/10.1073/pnas.090500397

Braun, T., Philippsen, A., Wirtz, S., Borgnia, M., Agre, P., Kühlbrandt, W., Engel, A., & Stahlberg, H. (2000). GlpF : a structural variant of the aquaporin tetramer. In Molecular biology and physiology of water and solute transport (pp. 13–22). Kluwer Academic. https://doi.org/10.1007/978-1-4615-1203-5